Datasets:
ClarusC64
/
ABX-HT-005_neurotoxicity_threshold_shift-v0.1

Dataset card Data Studio Files
xet
Community
row_id
string
series_id
string
timepoint_h
int64
host_model
string
drug
string
plasma_conc_mg_L
float64
csf_conc_mg_L
float64
expected_csf_conc_mg_L
float64
csf_deviation
float64
bbb_penetration_ratio
float64
expected_bbb_ratio
float64
ratio_deviation
float64
neuro_marker_index
float64
neuro_coherence_index
float64
exposure_index
float64
stress_index
float64
later_severe_neuro_flag
int64
assay_method
string
source_type
string
neuro_threshold_shift_signal
int64
earliest_neuro_threshold_shift
int64
notes
string
ABXHT005-TR-0001
S1
0
human_sim
cefepime
10
0.5
0.5
0
0.05
0.05
0
0.1
0.9
0.1
0.1
0
pk_csf_neuro_panel
simulated
0
0
baseline
ABXHT005-TR-0002
S1
12
human_sim
cefepime
12
0.6
0.6
0
0.05
0.05
0
0.12
0.88
0.85
0.9
0
pk_csf_neuro_panel
simulated
0
0
tracks expected
ABXHT005-TR-0003
S1
24
human_sim
cefepime
12
1.1
0.6
0.5
0.092
0.05
0.042
0.55
0.35
0.9
0.9
0
pk_csf_neuro_panel
simulated
0
0
first shift
ABXHT005-TR-0004
S1
36
human_sim
cefepime
12
1.3
0.6
0.7
0.108
0.05
0.058
0.62
0.3
0.9
0.9
0
pk_csf_neuro_panel
simulated
1
1
confirmed onset
ABXHT005-TR-0005
S1
72
human_sim
cefepime
12
2.4
0.6
1.8
0.2
0.05
0.15
0.85
0.2
0.9
0.9
1
pk_csf_neuro_panel
simulated
1
0
severe later
ABXHT005-TR-0006
S2
0
human_sim
meropenem
15
0.3
0.3
0
0.02
0.02
0
0.1
0.9
0.1
0.1
0
pk_csf_neuro_panel
simulated
0
0
baseline
ABXHT005-TR-0007
S2
24
human_sim
meropenem
16
0.32
0.32
0
0.02
0.02
0
0.12
0.86
0.9
0.9
0
pk_csf_neuro_panel
simulated
0
0
stable
ABXHT005-TR-0008
S2
48
human_sim
meropenem
16
0.33
0.33
0
0.021
0.02
0.001
0.12
0.84
0.9
0.9
0
pk_csf_neuro_panel
simulated
0
0
stable
ABXHT005-TR-0009
S3
0
human_sim
cefepime
10
1.8
0.5
1.3
0.18
0.05
0.13
0.7
0.3
0.9
0.9
1
pk_csf_neuro_panel
simulated
0
0
baseline ratio high
ABXHT005-TR-0010
S4
0
human_sim
cefepime
12
1.3
0.6
0.7
0.108
0.05
0.058
0.62
0.3
0.9
0.3
1
pk_csf_neuro_panel
simulated
0
0
stress low