{"text": "The goal \u00a7 Accessible (and inclusive) availability of the three runic inscriptions and their metadata according to the FAIR principles 1. The state of the art \u00a7 Damaged writing support \u00a7 Progressive difficulty in reading the inscriptions \u00a7 No ontological description of the texts and of the metadata available to date 3. The Method \u00a7 Texts: TEI- EpiDoc XML (v. 9.5) and CRMtex (2.0 model) \u00a7 Metadata: CRMtex (2.0 model) 4. Example: the inscription on the right shoulder vRunic texts: TEI-EpiDoc XML (v. 9.5) vMetadata: CRMtex (2.0 model) 5. Next Steps \u00d8RTI-Dome \u00d8Lemmatization \u00d8Linking ontological description to the 3D model Runes in Venice. Ontological description of the runic inscriptions on the Piraeus Lion (Venetian Arsenal) Paola Peratello Universit\u00e0 Ca\u2019 Foscari Venezia paola.peratello@unive.it DH Benelux 2024, Leuven: Breaking Silos, Connecting Data: Advancing Integration and Collaboration in Digital Humanities
TEI/EpiDoc XML Photos by Paola Peratello, 2023, on concession of the Comune di Venezia and of the Arsenale di Venezia. 1. N\u16cd\u16d8un\u16d0\u16b1\u16ed\u16b1\u16c1\u16cd\u16d0\u16c1\u2026-n\u16b1\u16a6\u16c1\u16cdN\u16b1\u16ed\u16a6N\u16c1\u16b1\u16ed\u16c1\u16cd\u16b4 2. \u2026\u16a6u\u16b1\u16da\u16c1\u16a0\u16b1----Nu\u16b4\u16ed-u/\u16b1\u2026-\u16ac-\u2026-----\u16d0-\u2026 3. \u2026u\u16a0\u16b1u\u16b4\u2026\u16b1\u2026\u16cb--\u2026--\u2026uNn\u16a0N\u16b1n\u16ed Check the bibliography here Transrunification from Sn\u00e6dal 2016 Ontological description according to CIDOC-CRM and CRMtext Check the project here", "label": "poster"}
{"text": "Figure 8. Crystal structure of both a type II inhibitor, ima7nib, and a type IV inhbitor, GNF-\u00ad\u20102, bound to the kinase domain of c-\u00ad\u2010 Abl (3K5V.pdb). GNF-\u00ad\u20102 is a fully allosteric inhibitor of WT Abl and rescues type I/II inhibitor e\ufb03cacy against T315I both in vitro and in vivo. Gly250 Tyr253 Glu255 Met351 Phe359 Thr315 In addi7on to playing an essen7al role in cellular energe7cs, kinases and their associated signaling pathways regulate a plethora of intracellular processes. When aberrantly expressed or controlled, kinases can cause cellular dysregula7on and contribute to the onset of several diseases, including cancer. Based on the fundamental understanding of kinase dysregula7on in cancer biology, the discovery of small organic molecules to alter kinase func7on has culminated in the development of targeted cancer therapy. However, limited selec7vity and the emergence of drug resistance remain fundamental challenges for current modern medicinal chemistry e\ufb00orts aimed at the development of kinase inhibitors that are both safe and e\ufb00ec7ve as long-\u00ad\u2010term treatments. Muta7ons resistant to classical ATP-\u00ad\u2010compe77ve (Type I/II) kinase inhibitors emerged at a rapid pace and oTen limit the success of newly available targeted cancer therapies. At present, there are more than 70 individual muta7ons at more than 50 muta7on sites conferring di\ufb00erent levels of ima7nib resistance found within CML pa7ents. Recently, a number of Type IV kinase inhibitors that func7on via a fully allosteric mechanism of ac7on have demonstrated promise toward addressing muta7on dependent drug resistance. BINDING STUDIES OF TYPE I, II, AND IV KINASE INHIBITORS AGAINST ABL KINASE USING BACK-\u00ad\u2010SCATTERING INTERFEROMETRY MOA FOR ALLOSTERIC INHIBITORS THAT OVERCOME DRUG RESISTANCE Fei Shen, Nathaniel Gilbert, Robert R. Lavieri, Richard J. Isaacs, Scot R. Weinberger Molecular Sensing, Inc. Back-\u00ad\u2010scaNering Interferometry The Back-\u00ad\u2010scaYering device is a micro-\u00ad\u2010scale interferometer (see \ufb01gure 4). The BSI device consists of a HeNe laser, a microchip, and a CCD camera. The microchip receives light from the laser and illuminates the sample containing channel. As light passes into the channel, interference fringe paYerns arise and a camera images the fringes (Figure 4). When molecules bind, the resultant complex causes a change in molecular mean polarizability that is measured as a fringe paYern shiT. Monitoring the change in fringe phase as a func7on of ligand concentra7on allows equilibrium dissocia7on constant (Kd) measurements to be performed. SeRng up the BSI assay BSI Kd determina7ons are performed in end-\u00ad\u2010point fashion, with target and ligand pre-\u00ad\u2010incubated to establish equilibrium. Target and ligand concentra7ons are chosen to ini7ate pseudo-\u00ad\u2010\ufb01rst order binding condi7ons, for which the target is typically held at a sparing concentra7on and the ligand is present in excess to avoid ligand deple7on during the binding process. Back-\u00ad\u2010scaNering Interferometry Kinase inhibitor binding analysis and BSI data validaTon References Materials and Methods www.molsense.com Sample Reference Figure 11. Prepara7on of kinase Inhibitors. Ima7nib, dasa7nib, nilo7nib and GNF-\u00ad\u20105 were prepared as 50 mM working stocks in 100% DMSO. Dose response series were created by dilu7ng each working stock with MOPS bu\ufb00er to establish the appropriate target concentra7on range for each binding system using a 12-\u00ad\u2010point doubling dilu7on (range: 50 pM \u2013 125 \u03bcM). DasaTnib (nM) NiloTnib (nM) ImaTnib (nM) c-\u00ad\u2010Abl Kinase IC50 KD IC50 KD IC50 KD Wild-\u00ad\u2010type 1.83 1.08 17.69 13.3 527 472 M351T 1.61 0.42 7.8 2.7 926 1086 Q252H 5.6 5.49 46.7 47.6 733 961 H396P 1.95 0.7 42.6 32.6 1280 1228 T315I 137 86.5 696 761 9221 4050 Figure 9. 9A. The Kd of ATP for both WT and T315I Abl is about 4-\u00ad\u20105 micromolar. 9B. The Kd values for GNF-\u00ad\u20105 vs. WT and T315I Abl are about 510 nM and 130 nM respec7vely. 9C. Interes7ngly, in the presence of a satura7ng amount of GNF-\u00ad\u20105 (50 \u03bcM) the binding curve for ATP is right-\u00ad\u2010shiTe", "label": "poster"}
{"text": "SUBUrB Software zur Unterst\u00fctzung von Bibliotheken bei urheberrechtlichen Bewertungen \u2022 Problem: Bestandsl\u00fccken bei Bibliotheken \u2022 Fehlende B\u00fccher m\u00fcssen beschafft werden \u2022 Pr\u00fcfung des Urheberrechts \u2022 Gemeinfreie B\u00fccher k\u00f6nnen ausgeliehen und kopiert werden \u2022 Gesch\u00fctzte B\u00fccher m\u00fcssen (wenn verf\u00fcgbar) gekauft werden \u2022 Pr\u00fcfungen sehr aufwendig \u2022 Bisher manuell erledigt Literatursoftware SUBUrB \u2022 Pr\u00fcfungen lassen sich automatisieren \u2022 Urheberrecht folgt klaren Regeln \u2022 Autoren seit \u00fcber 70 Jahren tot: Werk gemeinfrei \u2022 Sonst: Werk gesch\u00fctzt \u2022 Software recherchiert Todesdaten \u2022 Beurteilung je nach Informationsstand Idee \u2022 Nutzer k\u00f6nnen B\u00fccherlisten anlegen \u2022 Software sucht nach Daten in Katalogen \u2022 Deutsche Nationalbibliothek \u2022 Landesbibliotheken \u2022 \u2026 \u2022 Erg\u00e4nzung fehlender Daten \u2022 Urheberrechtliche Beurteilung wird erstellt \u2022 Triviale F\u00e4lle k\u00f6nnen auch bei fehlenden Daten abgehandelt werden \u2022 Buch \u00e4lter als 180 Jahre \u2022 Buch j\u00fcnger als 70 Jahre \u2022 Ergebnisse werden \u00fcbersichtlich dargestellt Funktionsumfang \u2022 Implementierung eines Prototypen \u2022 Vorstellung der Idee+Prototyp auf dem IRIS 2015 \u2022 2. Platz beim Best Paper Award Aktueller Stand \u2022 Kooperation mit der Europ\u00e4ischen EDV-Akademie des Rechts (EEAR) \u2022 Suche nach Partnern (Bibliotheken) \u2022 Anpassung an Bed\u00fcrfnisse der (sp\u00e4teren) Kunden \u2022 Erweiterungen f\u00fcr Digitalisierungsprojekte \u2022 Verwaiste und vergriffene Werke Entwicklung juris-Stiftungsprofessur f\u00fcr Rechtsinformatik Prof. Dr.-Ing. Christoph Sorge Cand. iur. Stefan Hessel Frederik M\u00f6llers, M.Sc. \u00dcbersicht \u00fcber verwaltete B\u00fccher (Screenshot des Prototypen). Verwaltung einzelner Werke (Screenshot des Prototypen). Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz.", "label": "poster"}
{"text": "Draft Simulation studies for the ATLAS track-counting luminosity measurement Giulia Ripellino on behalf of the ATLAS Collaboration Abstract A precise measurement of the luminosity is a key component of the ATLAS physics programme. ATLAS uses several detectors and algorithms to determine the luminosity. The absolute calibration of these algorithms is carried out in LHC runs with special beam conditions at low luminosity. The track-counting luminosity measurement is used to determine the calibration transfer from the low-luminosity regime to the high-luminosity conditions typical of standard physics data taking, and to monitor the long term stability of the default luminosity method. The track-counting method works by counting the number of reconstructed tracks from charged particles inside the Inner Detector. The average number of charged particles in randomly-triggered events is proportional to the average number of inelastic collisions per event and can therefore be used to compute the luminosity. This poster presents simulation studies for the ATLAS track-counting luminosity measurement. A toy simulation model is used to study the underlying distribution of the number of tracks and to illustrate the linearity between the average number of tracks and the luminosity. Full ATLAS MC simulation is used to assess effects related to the reconstruction of the tracks and their effect on the linearity. Method The LHC bunch luminosity is given by Lb = \u00b5fr \u03c3inel (1) where \u00b5 is the average number of inelastic pp collisions per event, fr the LHC revolution fre- quency, and \u03c3inel the pp inelastic cross-section. \u2022 The track-counting measurement uses the av- erage number of charged tracks of randomly triggered events to measure the luminosity. \u2022 The visible interaction rate is given by \u00b5vis = \u27e8Ntracks\u27e9= Nevents P i=1 N i tracks Nevents \u221d\u00b5. (2) \u2022 Two different track selections are explored Selection |\u03b7| N Pixel Holes |d0/\u03c3d0| pT 2016 < 2.5 0 < 7 > 0.9 GeV 2017 < 1.0 \u22641 Track selections for the track-counting measurement, based on the TightPrimary selection defined in Ref. [1]. Track-multiplicity pdf in MC Normalized track distributions in a Pythia8 A3 minimum bias MC sample with exactly one pp interaction per event. The distributions can be interpreted as the track-multiplicity probability density functions (pdfs) for each track selection. Linearity in toy simulation The linearity between \u00b5vis and \u00b5 illus- trated in a toy simulation model. For each event, the number of interactions is determined from a Poisson distribution with mean \u00b5. The number of tracks per interaction is then sam- pled from the track-multiplicity pdf. The result- ing track distribution is used to determine the mean number of tracks per event for the spe- cific value of \u00b5. The proportionality constant between \u00b5vis and \u00b5 corresponds to the mean of the track-multiplicity pdf. Linearity in full simulation Relation between \u00b5vis and \u00b5 in full simula- tion. A Z \u2192\u00b5\u00b5 MC sample with overlaid mini- mum bias events as pileup is used for the study. Tracks from the hard scatter interaction are ex- cluded in the number of reconstructed tracks. The \u00b5-dependence is parameterised by a first- order polynomial, fitted in the range \u00b5<40. The non-linearity results from the effects of track reconstruction efficiency and fake tracks. The higher non-linearity in the 2017 selection is likely due to the looser track-selection requirements. Track-multiplicity pdf in data The 2017 track selection MC pdf is compared to data in order to assess the modelling of the track multiplicity. The data track-multiplicity pdf is derived from the distribution of the number of tracks per event in data with \u27e8\u00b5\u27e9\u226a1 (left), selected for the purpose of eliminating events with more than one pp interaction. Events with zero tracks can arise either from bunch crossings where no pp interaction occurred (\u201cempty crossings\u201d), or from bunch crossings with one pp interaction in which no track satisfied the track-selection criter", "label": "poster"}
{"text": "NF Research Tools Database: An experimental resource database for the neurofibromatosis community 1 Sage Bionetworks , Seattle, WA, USA 2 Gilbert Family Foundation, Detroit, MI, USA Correspondence: nf-osi@sagebionetworks.org Brynn Zalmanek, MLIS1, Robert Allaway, PhD1, James Goss, PhD2, Ashley Clayton, MS1, James Eddy, PhD1, Kaitlin Throgmorton, MLIS1, Jineta Banerjee, PhD1, Kalyan Vinnakota, PhD2, Caroline Morin, BS2, YooRi Kim, MS2, Justin Guinney, PhD1 Approach Highlights \u25cfWe are developing a centralized resource database for NF1 research tools, including animal models, cell lines, antibodies, genetic reagents, and biobanks. \u25cfThe research community will be able to contribute feedback, usage notes, and other observations about these tools to the database. \u25cfWe are recruiting testers to participate in an upcoming evaluative design study to ensure that this resource is useful for the research community. Background & Introduction \u25cfWhen the Gilbert Family Foundation (GFF) started to fund investigators with little or no prior experience in NF1 research, it became evident that research progress was impacted by the challenge of identifying, evaluating, obtaining, and/or creating the tools required for their research. \u25cfWhile a variety of databases exist for investigators to find useful research tools these databases are usually: \u25cbSpecific to the type of resource, \u25cbToo broad in scope, and/or \u25cbDo not include newly developed or unpublished models \u25cfTo accelerate NF research, we are building the NF Research Tools Database, a database and companion web application to store and explore information about model resources specifically relevant to the NF community. \u25cfThe database will include key attributes for each resource and contributed observational data from publications and the research community. \u25cfThe database development consists of three phases (Figure 1): \u25cbDesign (current phase): Generation of a prototype database website. \u25cbPilot: Visitors can search and explore the contents of the database through the website. \u25cbLong-term Development: Members of the NF community will be able to submit resource attributes or observations through a user friendly submission process. Acknowledgements The project team would like to thank Ljubomir Bradic, Stockard Simon, Bruce Hoff, Jay Hodgson, Kevin Boske, and Ryan Luce for helpful discussions regarding the design and development of this application. Icons made by Eucalyp from www.flaticon.com. This work is supported by the Gilbert Family Foundation. Conclusions & Future Directions \u25cfGFF and Sage Bionetworks have made significant progress in developing a prototype tools database and companion web application for NF1 research resources. This resource could be a one-stop-shop for learning about the various experimental tools that have been generated by the NF1 research community \u25cfAfter the prototype phase, we plan to expand the scope of this database to include NF2 and schwannomatosis-related resources \u25cfWe encourage feedback from the research community, particularly: \u25cbWhat NF1-relevant animal models, cell lines, antibodies, genetic reagents, and biobanks you would like to see listed in the database. \u25cbWhat types of research resource attributes you consider when, for example, selecting a cell line for an experiment. \u25cbWhether you would be likely to contribute observational information about a research resource to a database like this. \u25cfWe are recruiting testers to participate in an upcoming evaluative design study. Please contact nf-osi@sagebionetworks.org if you are interested in participating in this study (Q4 2021) or contributing information about an NF1 research resource! Evaluating External Data Sources & Prior Work Designing a Data Model Identifying Use-Cases Prototype Design & Evaluation \u25cfGFF developed an alpha version of the database, incorporating tools utilized within GFF research programs and soliciting feedback from their awardees on how to best classify and characterize each tool. \u25cfSage then condu", "label": "poster"}
{"text": "In Situ Origins of Hot Jupiter Isolation Brandon Radzom1, Songhu Wang1, Bonan Pu2 1Indiana University, 2Cornell University \u2022 Outstanding issue: Hot Jupiters are more observed to be more isolated than warm Jupiters \u2022 Context: \u2022 Widespread prevalence of super-Earths in compact multiple-planet systems \u2022 Super-Earth pairs packed near the boundary of Hill instability (Pu & Wu 2015) \u2022 Most exhibit \u201cpeas in a pod\u201d structure (Weiss et al. 2018) \u2022 Many are sufficiently massive to trigger runaway accretion (Lee et al. 2014; Batygin et al. 2016) \u2022 Our work: Use N-body simulations of mass-boosted super-Earths to demonstrate that in situ formation naturally produces observationally isolated hot Jupiters and warm Jupiters with nearby low-mass companions Introduction N-body Simulation Set-up References: Batygin, K., Bodenheimer, P. H., & Laughlin, G. P. 2016, ApJ, 829, 114; Lee, E. J., Chiang, E., & Ormel, C. W. 2014, ApJ, 797, 95; Millholland, S. C., He, M. Y., & Zink, J. K. 2022, arXiv e-prints, arXiv:2207.10068.; Pu, B., & Wu, Y. 2015, ApJ, 807, 44; Weiss, L. M., Marcy, G.W., Petigura, E. A., et al. 2018, AJ, 155, 48, Main Results Our final systems exhibit three key properties (Figure 1): 1. Hot Jupiter Isolation. Period ratios of our hottest Jupiters (\ud835\udc43< 5 days) relative to their nearest companions are typically larger than those of warm Jupiters (by a factor of ~2). Thus, a large fraction of hot Jupiters' companions would not yet be detectable through transit timing variations or transit searches. 2. Dynamical Sweet Spot. Inner companions rarely survive for the hottest Jupiters but are seldom destroyed for hot Jupiters in the dynamical \u201csweet spot\u201d (5 < \ud835\udc43< 7 days). This sweet spot marks a dramatic drop in the average period ratio and a transition to inner companion configurations. 3. Mirrored Architectures. Our hot and warm Jupiter systems mirror each other\u2014 inner companion period ratios steadily increase with giant period while outer ratios tend to decrease. Step 1: Generate Stable Peas-in-a-Pod Systems We generate 200 peas-in-a pod systems, each with eight super-Earths orbiting a solar mass star. We then boost the mass of one planet per system to 1 Jupiter mass (MJ), driving instability, and integrate to \ud835\udc61= 10 Myr. Step 2: Provide Mass Boost Dynamics: The giant\u2019s position chiefly determines the final configuration since companion-companion collisions dominate (Figure 2). Hot Jupiter Isolation Dynamical Sweet Spot Mirrored Architectures Figure 2. Fraction of companions that avoid collisions & ejections (black squares; left axes) and average timescale for such events (blue shading; right axes) as a function of planet position, stacked for each giant\u2019s position. Giant positions are shown schematically at the top of each panel (large black circles). Figure 1. Final giant period ratios with their nearest neighbor as a function of giant period, with orientations indicated (red rightward and blue leftward triangles). The mirror effect between our red and blue triangles may be astrophysical so long as peas-in-a-pod systems become truncated (see Millholland et al. 2022). A long planet chain exists outside the hot Jupiter, resulting in collisional cascade once two adjacent planets reach \ud835\udc52\u2248\ud835\udc52\ud835\udc50/2. The hot Jupiter also merges with its nearest inner companion, leaving it isolated. The hot Jupiter has two inner companions which quickly merge and are then Hill stable for all time, since the Jupiter will \u201cfilter\u201d \ud835\udc52excitation. The number of companions on either side of the giant dictates the system\u2019s fate, causing a mirrored effect for hot and warm Jupiter configurations. Sweet spot Innermost period @ 3-day pile- up Orbital eccentricities are bound by orbit-crossing value \ud835\udc52\ud835\udc50 25 simulations run for each planet boosting position (25 \u00d7 8 = 200) Spacing based on the Equal Mutual Separation scheme\u2014 pairs initially Hill stable but pushed near \ud835\udc3e= 3.5 threshold after mass-boosting \ud835\udc43~6 d \ud835\udc43~4 d \ud835\udc43~30 d", "label": "poster"}
{"text": "sdfsafdsa Using digital tools and methods for a systematic literature review Representing social media interactions and meanings as knowledge graphs Creating a curation-enabled social media research archive The Connective project A three-year EU-funded research project (2020-2023) aiming to: \uf076Reveal how memory practices on social network sites inside and outside Lithuania, mediated by contested heritage, enable the construction of multiple collective identities. \uf076Advance digital curation approaches to social media data and its future preservation and access for research. 2. Based on the ontology, we established a property graph schema using the Cypher query language to design and implement a Neo4j database of social media conversations on Lithuanian heritage, memory and identity. We adopted Open Archives Information System (OAIS) definitions of Submission, Archival, and Dissemination Information Packages, to ensure integrity and authenticity of research data collected from social media platforms, while also ensuring their intelligibility in the research process. Digital resources, methods and tools in the research lifecycle The Connective Digital Memory in the Borderlands project We used the Publish or Perish reference collection software to conduct 20 faceted queries on Google Scholar, based on combinations of Boolean query expressions for difficult heritage and social media platforms. The queries yielded 1,201 documents. Costis Dallas, Ingrida Kelp\u0161ien\u0117, Rimvydas Lau\u017eikas Connective Research Group, Faculty of Communication, Vilnius University This poster reports on research conducted as part of \u201cConnective digital memory in borderlands: a mixed-methods study of cultural identity, heritage communication and digital curation on social networks\u201d. The Connective project was funded by the European Social Fund under grant agreement 09.3.3-LMT-K-712-17-0027 with the Research Council of Lithuania (LMT-LT). \uf0a711 researchers \uf0a79 themes \uf0a772 topics \uf0a74 languages \uf0a725,455 Facebook threads \uf0a7264,954 messages \uf0a793,551 users \uf0a775 interviews Investigating the semiotic circulation of agency through knowledge graphs \uf076Extending nexus theory to show how attitudes on Soviet heritage move across social media, users and references to the dissonant past \uf076Investigating propagation across Neo4j person and message nodes Analyzing digital memories and perceptions of the past through qualitative content analysis \uf076Examining how Lithuanian everyday life and culture during the 1990s is represented on social media through identifications and memes \uf076Using MaxQDA and Neo4j for content and critical discourse analysis Comparing discourse constructs in actual and ChatGPT-produced social media content \uf076Investigating the use of ChatGPT to analyze and produce speculative SNS conversations on Lithuanian contested heritage Kelp\u0161ien\u0117, Ingrida, Donata Armakauskait\u0117, Viktor Denisenko, K\u0119stas Kirtiklis, Rimvydas Lau\u017eikas, Renata Stonyt\u0117, Lina Murinien\u0117, and Costis Dallas. 2023. \u2018Difficult Heritage on Social Network Sites: An Integrative Review\u2019. New Media & Society 25 (11): 3137\u201364. https://doi.org/10.1177/14614448221122186. Kirtiklis, K\u0119stas, Rimvydas Lau\u017eikas, Ingrida Kelp\u0161ien\u0117, and Costis Dallas. 2023. \u2018An Ontology of Semiotic Activity and Epistemic Figuration of Heritage, Memory and Identity Practices on Social Network Sites\u2019. SAGE Open 13 (3): 1\u201325. https://doi.org/10.1177/21582440231187367. Lau\u017eikas, Rimvydas, and Costis Dallas. 2024. \u2018The Message Is the Agent: Nexus and Semiosphere in Social Media Communication\u2019. In Semiotics and Visual Communication IV: Myths of Today, edited by Evripides Zantides and Sonia Andreou. Cambridge: Cambridge Scholars Publishing. Publications https://doi.org/10.5281/zenodo.10886535 Entities Relationships Deposit Thread Message Agent Topic PART_OF SHARED_FROM RESPONDED_TO FOLLOWED_BY REACTED_TO POSTED DISPLAYS CONNECTED_AS IN_CONTEXT REFERS_TO 1. We built a theory-laden CIDOC CRM-compatible ontology to represent how social media users belonging", "label": "poster"}
{"text": "An Analysis of Disabled Accessibility Transportation in the City of Chicago Manuel Luna Jr, Industrial Design, University of Illinois Chicago Dr. Joseph Hoereth, UIC \u2014 Institute for Policy & Civic Engagement (IPCE) According to the Regional Transportation Authority (RTA), all CTA and Pace buses are 100 percent accessible (RTA, 2023). The Americans with Disabilities Act holds these transportation systems to provide accessible features such as wheelchair securement areas, ramps, priority seating, and visual displays. In reality, 76% of stations are actually functional. The city of Chicago is constantly expanding their stations, not focusing this effort on the already established stations. Funding is going towards new station projects when some of the funding should be used for fixing the old stations that need it. Chicago Accessibility Compliance Program (CACP): The CACP focuses on ensuring that public spaces, transportation systems, and municipal buildings comply with accessibility standards outlined in the Americans with Disabilities Act (ADA). This initiative involves conducting audits, implementing necessary renovations, and providing resources to enhance accessibility for individuals with disabilities throughout the city. Chicago Business Leadership Network (CBLN): The CBLN collaborates with local businesses to promote inclusive hiring practices and provide support to employees with disabilities. Through education, training, and advocacy, the CBLN aims to increase workforce diversity and create employment opportunities for individuals with disabilities. Home Accessibility Program: This program provides financial assistance and incentives to property owners for retrofitting existing housing units to meet accessibility standards. By offering grants and resources, the city encourages the creation of accessible living environments for individuals with disabilities, thereby enhancing housing options and accommodation. These policies and initiatives reflect the City of Chicago's commitment to promoting inclusivity, accessibility, and empowerment for individuals with disabilities. By addressing various aspects such as infrastructure, employment, housing, and community support, Chicago strives to create a more inclusive and equitable environment for all its residents. BACKGROUND POLICY INITATIVES RECOMMENDATIONS RESEARCH OBJECTIVE METHODOLOGY FINDINGS \u2022 Increased funding for advocacy efforts from disability rights groups would significantly enhance their capacity to promote accessibility and inclusivity for individuals with disabilities. This funding could support initiatives such as grassroots organizing, public awareness campaigns, legal advocacy, and lobbying efforts aimed at influencing policymakers and stakeholders. \u2022 Implementing and upholding inclusive design standards and infrastructure would greatly bolster advocacy efforts for accessibility from disability rights groups. By ensuring that public spaces, buildings, transportation systems, and digital platforms are universally accessible, these standards not only remove physical barriers but also validate the rights and dignity of individuals with disabilities. This research seeks to examine the way the City of Chicago addresses issues of accessibility when it comes to people with disabilities and means of transportation. By analyzing existing policies, infrastructure improvements, and community engagement initiatives, this study aims to shed light on the effectiveness of current strategies in enhancing mobility and inclusivity for individuals with disabilities within the city's transportation network. Additionally, it seeks to identify potential areas for improvement and recommendations for fostering a more accessible and equitable transportation system for all residents of Chicago, regardless of ability. Introduction: The rights and well-being of individuals with disabilities have increasingly gained attention in policy circles and societal discourse. In urban environments", "label": "poster"}
{"text": "www.postersession.com g Remote sensing has been used in many environmental studies because of its capacity to provide information rapidly on large and hard-to-reach areas. Recently, many programmes such as ASTER, Landsat and Copernicus Sentinels have provided satellite imagery of both high temporal and spatial resolutions free of charge. These data, combined with fieldworks and geophysical measurement , can lead to the finding of solutions for modern challenges such as climate change, natural hazards and increasing population growth. We used these technologies in a region which is both sensitive to and vulnerable to these phenomena, the karst environment of the Tabular Middle Atlas (TMA) of Morocco, in order to study the vulnerability of its natural water reserves . The TMA of Morocco contains an important water reservoir, located in Liassic carbonate rocks (dolomite and limestone), and used for everyday activities in cities such as Agourai, Fez, El Hajeb, Ifrane and Meknes. Because of its importance and the value it holds in the economy of the region it has been described as ch\u00e2teau d\u2019eau. The most recent studies conducted in this region show that water quality is deteriorating due to anthropologic activities and natural processes. The present study proposes the use of earth observation, geophysical methods and free available data to map various forms of karst (avens, dolines, poljes...) and fault systems; these are the most fragile hotspots where the water reservoir can be easily penetrated in this karst system, with pollutants infiltrating and reaching groundwater and eventually identify most vulnerable areas. We intend to answer the question related to the part played by each fracture system, in order to find out which one is responsible for the infiltration of surface water and consequently is contributing to the development of sinkholes, and also to find out which system is draining water from the Causse to the basin. The aim of this study is to enhance the understanding of the hydrogeological system of the TMA, to improve the fracture database, to explore the profitability of new methodology combining space technology, applied geophysics and ground-based field work, and to establish a complete picture of vulnerable areas where sinkholes and human activities are degrading the quality of groundwater. There are three priority questions to be answered: -What is the direction of the fault systems involved in water infiltration, and probably led to the development of different karst landforms? -What is the predominant location of the sinkholes responsible for the turbidity and chemicals observed in water springs? -Where are water-soluble substances such as fertilizers, pesticides and herbicides accelerating carbonate dissolution due to human activities? Methods and materials Conclusions A.Muzirafuti1, M. Boualoul 1, G.Randazzo 2 , A. Allaoui1, S. Lanza 2, H. El Ouardi3, H. Habibi3, H. Ouhaddach3 1 Team of applied geophysics, Nat Ress. and Heritage, Dept. of Geology, Fac. of Sciences, University of Moualy Ismail, BP. 11201 Zitoune, Meknes, Morocco 2 Section of Earth Sciences, Dept. of Math and Computer Science, Physical Sciences and Earth Sciences, Univ. of Messina. Via F. Stagno d'Alcontres, 31 98166 - Sant'Agata di Messina, Messina, Italy \u2013 3 Team of tec mapping, Dept. of Geology, Fac. of Sciences, University of Moualy Ismail, BP. 11201 Zitoune, Meknes, Morocco - Synthetic map of various karst landform location Fieldworks conducted in numerous locations around major faults, water springs and on different karst landforms helped us validate remote sensing results. We noticed that a big number of sinkholes are located in fractured carbonate rocks in low laying areas, some of them were identified in agricultural areas filled with basalts or clay sediments. Structural study conducted on carbonate fractures revealed that 37 % represent NE-SW fault system while 22% and 30 % represent Sub-meridian and NW-SE Fault faults systems resp", "label": "poster"}
{"text": "SST CCI Phase-II Requirements for Sea Surface Temperature data sets for Climate Research and Services Nick Rayner, Met Office Hadley Centre, UK SST information is needed by almost all applications in climate research and by many climate service activities. The needs of these diverse fields are varied and can seem confusing without undertaking a systematic user requirements gathering exercise. The ESA Climate Change Initiative SST project has recently reviewed requirements for climate SST data sets from a wide range of applications in climate science and services; this updates its assessment undertaken over five years ago. Responses were received from scientists in 20 countries in North and South America, Europe, Asia, Africa and Australasia. A selected, preliminary analysis of responses is presented here; the final analysis will be presented in the updated User Requirements Document (see http://www.esa-sst-cci.org/ over the coming months). On what kind of grid would you like the data? Other here included: cubed sphere; ORCA (NEMO) grid; and equal area. Please classify this application into one or more of the following applications/interests. Other here included: climate feedbacks; Combined historical, near real-time, and seasonal applications; air quality modelling; comparison with in-situ; interpretation and analysis of hydrographic data; fisheries; for assessing processes; atmospheric chemistry; analysis of relationship between SST and crop productivity and drought; responses of marine top predators to climate change; global numerical weather prediction and high-resolution numerical weather prediction; climate impact model evaluation; ocean heat content comparison; and calibration of proxy data. On what data level does the application require observations? For your application, is it more useful to have all SSTs for the same local time or the same universal time? What spatial coverage is required? What is the temporal coverage needed for your application? How quickly you need data: Is the concept of an interim climate record important to your application? Here respondents gave responses between less than one day and 30 days. SST depth. Providers of satellite SST products variously aim to report temperatures for either the radiometric skin depth they observe or for sub-suface depths. For your application, which type(s) of SST is (are) most relevant? Other included SST1m. The SST CCI project will make Level 2 and Level 3C products available in a flexible format containing information enabling users to derive the SST and its uncertainty adjusted to different depths and times appropriate to their needs. We also propose to make available a standard product file which provides information in a simpler-to-use form. This standard file would contain SSTskin at the observation time, plus one other adjusted SST If you would use this, which combination of adjustments is most relevant to your application? Other here gave no specific alternatives Is your application sensitive to locally-correlated errors (correlated within synoptic scales and uncorrelated beyond)? If SST uncertainty information were to be provided as a parametrised covariance matrix, would you use this? If SST uncertainty information were to be represented by an ensemble (a set of plausible realizations of each SST field which span the uncertainties in the data), what size of ensemble would you need for your application (how many members)? not applicable 3 to 10 10 to 50 50 to 100 100 need guidance How would you like quality/confidence information to be communicated? Other here included requests for uncertainty information or an ensemble only and not to include flags as well. What information would you like to be within the data files? Other here included: gap filled or no gap filled / how?; info on anomalously cold data; data points that may contain extreme upwelling; and information about difference w.r.t. adjacent pixels. What other ancillary data from external sources", "label": "poster"}
{"text": "www.rethinkaction.eu This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement No 101037104 A platform to support local land-use decision making. Objective The main objective of RethinkAction is to engage citizens and decision-makers to participate in the energy transition and actively support climate adaptation and mitigation. Six representative case studies form the backbone of the RethinkAction project, covering the main regional differences related to climate change. Together with our End-User-Community we create an Integrated Assessment Platform. The user-friendly platform will empower citizens, stakeholders, and decision-makers to analyse climate change and incorporate climate action into the decisions that will affect our lives in the coming decades. Analysis at EU / global level Analysis at local level Land use-based Adaptation and Mitigation Solutions (LAMS) catalogue High-resolution climate data and land use maps. Climate change impacts and risks in each case study Land use-based Adaptation and Mitigation Solutions catalogued at local, EU and global scales Multiscale evaluation framework: 1) Future scenarios consistent across scales 2) Local system dynamic mo- dels for the integrated assessment of solutions 3) An upscaling function for solutions to EU and global scales (WILIAM IAM). \u2022 \u2022 \u2022 1 Diagnosis 2 LAMS feasibility 3 Simulati on Interested? Engage! Help to make high-level information on land-use and climate change more accessible to people\u2019s lives. Join our End-User-Community: Help to shape the direction in which RethinkAction is to be further developed. Expand and internationalise your professional network. Receive exclusive invitations to work meetings, training sessions and conferences organised by the project consortium. \u2022 \u2022 \u2022 What would happen if the LAMS assessed at local level\u2026. \u2026would be applied at EU / global level in all feasible locations? Upscaling solutions Simulati on with system dynamics integrated assessment model [WILIAM] An impression of the platform", "label": "poster"}
{"text": "1 INTRODUCTION Depuis des d\u00e9cennies, la Station Biologique de Roscoff suit la diversit\u00e9 de s communaut\u00e9 s planctonique s a u larg e de Roscoff, avec des pr\u00e9l\u00e8vements bimensuels sur les si tes \"Estaca de\" et \"SOMLIT-Asta n\" , au Nord -Es t de l '\u00cel e de B atz. Plusi eurs m\u00e9t hodes sont utilis\u00e9es pour d\u00e9nombrer les cellules , d ont la micro scopie o ptiqu e po ur les e sp \u00e8c es > 20 \u00b5m , et la cyt om\u00e9 trie en fl ux p our les esp \u00e8ces <20 \u00b5m*. La cy tom \u00e9trie en flu x permet de distinguer les groupes fonctionnels suivants : (i) les cyanobact\u00e9ries du genre Synechococcus, (ii) les picoeucaryotes photosynth\u00e9tiques, (iii) les nanoeucaryotes photosynth\u00e9tiques (iv) les algues Cryptophytes (v) les bact\u00e9ries et (vi) les virus marins Les donn\u00e9es de diversit\u00e9 phytoplanctonique de Roscoff obtenues par microscopie optique on t d\u00e9j\u00e0 \u00e9t\u00e9 bien \u00e9tudi\u00e9es par le laboratoire et ont m is en \u00e9viden ce u ne dynamiq ue saisonni\u00e8 re t r\u00e8s marqu\u00e9e avec des successions d\u2019esp\u00e8ces au c ours de l\u2019ann\u00e9e (Caracciolo et al. 2022). Ce projet, focalis\u00e9 sur les donn\u00e9es obtenues par cytom\u00e9trie en flux avait pour objectif : (1) d e fair e u n inventair e de s donn\u00e9e s disponible s et d es protocol es utilis \u00e9s po ur l es collecte r, ( 2) de d\u00e9termi ner les dynamiq ues saisonni\u00e8 res des principaux groupes fonctionnels distingu\u00e9s po ur le site SOMLIT- Ast an e t ( 3) de d\u00e9ter min er si les blooms saiso nni ers de Synecho coccus avaient chang\u00e9 de date au cours des deux derni\u00e8res 20 ans de donn\u00e9es \u00c9chantillonnage et analyse de la mer \u00e0 la cellule Actuel Protocole 2 Anciens FACSCanto, FACSCan Flash frozen Sans Pluronic + Glutarald\u00e9hyde (fixateur) + Pluronic (surfactant) Echantillonnage (Neomysis) Cong\u00e9lation (-20\u00b0C) Cong\u00e9lation (-80\u00b0C) Conservation Niskin bottle Picoeucaryotes Analyse des abondance s des group es taxonomiques Cytogramme Fluorescence Side Scatter (SSC) Synechococcus Bact\u00e9ries Nanoeucaryotes + 5\u00b5l billes Polysciences fluoresbrite\u00ae Analyse (laboratoire) Microgouttelette charg\u00e9e contenan t 1 seule cellule FACSort D\u00e9tecteur et photomultiplicateur SSC : taille Fluorescence : naturelle ou fluorochrome Cytom\u00e9trie en flux : Dynamique saisonni\u00e8re au site SOMLIT-Astan 7 Trait de filet (eau de Roscoff) diatom\u00e9es Synechococcus ? nanoeucaryotes photosynth\u00e9tiques ? picoeucaryote photosynth\u00e9tique ? \u00a9 SBR 6 Cyanophage et Synechoccocus infect\u00e9e \u00a9 Sophie Le Panse, Plateforme MERIMAGE (SBR) 48\u00b046'40.1\"N 3\u00b056'15.0\"W 48\u00b043'55.9\"N 3\u00b058'58.0\"W 3 4 OUI Fig. 5. Variations saisonni\u00e8res des abondances des 5 groupes fonctionnels sur la p\u00e9riode d u 12/01/200 7 a u 18/12/201 9 (1 2 an s e t 1 1 mois ). Donn\u00e9 es issu es de la ba se PELAGO S, s ite SOMLIT-Astan surface. (d) Picoeucaryotes (e) Nanoeucaryotes (b) Bact\u00e9ries (c) Cryptophytes (a) Synechococcus Pico : 0.2-2 \u00b5m Nano : 2 \u2013 20 \u00b5m Micro : 20-200 \u00b5m *Phytoplancton \u2192 diversit\u00e9 de taille : 500 nm 5 8 Fig. 9. Variations saisonni\u00e8res des abondances de virus HNA (2013- 2020), site SOMLIT-Astan surface. Int\u00e9ractions virales Abondance virale (cellules/mL) Synechococcus est la cible de certains virus marins. Au site Astan, en surface, l'abondance des virus HNA (High Nucleic Acid content) qui ciblent Synechococcus, mais aussi des picoeucaryote s photosynth\u00e9tiqu es (communicati on personnel le de AC Baudo ux) va rie de f a\u00e7on saisonni \u00e8re, ave c un pi c en juin-juil let, p\u00e9r iod e de d\u00e9velopp ement des pico- et nanoeucaryotes. 500 nm 200 nm LIMITES & PERSPECTIVES \u2192 Biais potentiels dus au changement de protocole des donn\u00e9es PELAGOS \u2192 S\u00e9rie temporelle courte : description possible, mais conclusions limit\u00e9es \u2192 \u00c9chantillonnage tous les 15 jours insuffisant pour suivre les blooms d\u2019organismes unicellulaires \u00e0 cycle de vie court (de quelques heures \u00e0 quelque s jours) De nombreuses pistes sont possibles pour explorer davantage cette communaut\u00e9. Par exemple, des donn\u00e9es de fluorescence et de PA R (Rayonnemen t Photosynth\u00e9tiquemen t Actif ) son t disponible s su r l a ba se SOMLIT. Ces donn\u00e9es pourraient r\u00e9v\u00e9ler des changements physiologiques c hez", "label": "poster"}
{"text": "Resolving Surface Features on M Dwarfs that Host Transient Corotating Material Ben Tofflemire1,\u2020, Adam Kraus1, Andrew Mann2, Greg Mace1 1The University of Texas at Austin, 2UNC Chapel Hill \u202051 Pegasi b Fellow RIK 12 Toy Model Complex Periodic Variables Complex periodic variables (CPVs) exhibit narrow dimming events with variable morphologies and depths that are periodic with the stellar rotation. Dimming events emerge and disappear stochastically. CPVs are predominantly young (<~200 Myr), low- mass (M<0.4 M\u2a00), and rapidly rotating (P<1 d). The most likely explanation for this behavior is magnetically confined material orbiting in co-rotation with the star [1,2,3]. Monitoring with IGRINS We have monitored four CPVs in Upper Sco using the IGRINS spectrograph ([4,5], simultaneous H and K at R~45,000). Here, we showcase the results for RIK 12 ([6], M2.5 SpT, 5-10 Myr, Prot = 0.49 d, G mag = 13.8, K mag = 9.7) We reconstruct the stellar absorption profiles by computing spectral-line broadening functions using the saphires package [7]. We find: \u2022 Large rotational velocities (vsini>150 km/s), consistent with edge on viewing angles \u2022 Evidence for large and evolving spot features \u2022 No significant radial-velocity variability Modeling Surface Features The cadence and baseline of our observations do not allow for a full surface reconstruction. Still, we can use a toy model to investigate characteristics of surface features that are consistent with our observations. We find the amplitude of the line-profile deviations are challenging to reproduce with typical spot- photosphere surface brightness ratios in the NIR (~0.5). The depth and bread of the deviations are improved when incorporating polar spots. Our most extreme cases likely require obscuring dust. In summary, our spectra suggest the presence of: \u2022 Large, high-contrast (dark) spots near equator \u2022 Large polar spots \u2022 Potentially, obscuring dust Our sparsely sampled spectra highlight CPVs as prime candidates for future Doppler tomographic studies to fully reconstruct the stellar surface, and to measure the orientation and size of the transiting material. Resolution Element Rotational Phase Rotation Periods since K2 Signature of Dark Spots (or Obscuring Material) No evidence for RV variability Flux compared to a homogeneous surface Typical Residual Depth vsini Acknowledgements & References BMT acknowledges the Heising-Simons Foundation, and TESS Cycle 3 & 4 Guest Investigator Grants (80NSSC21K0780, 80NSSC22K0302) [1] \u2013 Bouma et al. 2024, AJ, 167, 38 [2] \u2013 Stauffer et al. 2017, AJ, 151,60 [3] \u2013 Zhan et al. 2019, ApJ 876, 127 [4] \u2013 Mace et al. 2016, SPIE, Vol. 9908 [5] \u2013 Mace et al. 2018, SPIE, Vol. 10702 [6] \u2013 Rizzuto et al. 2015 MNRAS,448, 2737 [7] \u2013 Tofflemire et al. 2019, AJ, 148, 245", "label": "poster"}
{"text": "1 2 3 4 5 6 7 8 BTSA** 1 et 2 Licence de biologie g\u00e9n\u00e9rale 2 et 3 Master 1 et 2 en Microbiologie Doctorat Nutrition animale, parasitisme et environnement BTSA** 1 et 2 Classe pr\u00e9paratoire ATS* \u00c9cole d\u2019ing\u00e9nieur Agroalimentaire- Agronomie Doctorat Nutrition animale et qualit\u00e9 des produits laitiers Doctorat Microbiologie et sant\u00e9 animale Doctorat Nutrition animale et qualit\u00e9 des produits laitiers \u00c9cole d\u2019ing\u00e9nieur en Agriculture avec classes pr\u00e9paratoires int\u00e9gr\u00e9es Master 1 et 2 en Sciences Animales Licence de biologie g\u00e9n\u00e9rale 1, 2 et 3 Master 1 et 2 en Microbiologie Doctorat S\u00e9lection g\u00e9n\u00e9tique et sant\u00e9 animale \u00c9cole d\u2019ing\u00e9nieur en Agriculture avec classes pr\u00e9paratoires int\u00e9gr\u00e9es Lucie Laurianne Valentin Blandine Des parcours vari\u00e9s vers le doctorat (bac+8), \u00e0 toi de cr\u00e9er le tien ! Bac *ATS : Adaptation de Technicien Sup\u00e9rieur **BTSA : Brevet de Technicien Sup\u00e9rieu r Agricole Cl\u00e9ment Centre Auvergne Rh\u00f4ne Alpes - Theix Route de Theix 63122 Saint-Gen\u00e8s-Champanelle, France Tel.: +33 (0)4 73 62 40 00", "label": "poster"}
{"text": "Tolerance of DNA Replication Stress Is Promoted by Fumarate Through Modulation of Histone Demethylation in Saccharomyces cerevisiae Faeze Saatchi1*, Ann L. Kirchmaier1 1 Department of Biochemistry and Purdue Center for Cancer Research , Purdue University, West Lafayette, IN 47907 *Current address: Department of Internal Medicine, Kidney Cancer Research Program, UT Southwestern Medical Center, Dallas, TX 75235 Abstract Conclusions Introduction me me Ku70/80 me me FH Ku70/80 H2A H2A H2A.Z H2A.ZH3K36H3K36 FH H2A H2A.Z H2A H2A.Z Malate Fumarate KDM2B Malate Fumarate Figure 1. Upon DNA damage, fumarase (FH) is recruited to sites of double stranded break (DSB) through interaction with the histone variant H2A.Z. Fumarate generated by DSB-associated FH acts as an inhibitor of \u03b1- ketoglutarate-dependent histone demethylase KDM2B causing an increase of H3 K36 methylation at DSBs. This, in turn, promotes binding of Ku70/80 to DSB ends and enhances DSB repair by NHEJ. Sensitivity of htz1\u0394 mutants to DNA replication stress caused by HU is suppressed by high cellular levels of the metabolite fumarate (achieved by addition of exogenous fumarate or deletion of Fumarase, Fum1p) Figure 3. Cells with genotypes as indicated were grown overnight in rich (YPD) medium, then 3 ul of 10-fold serial dilutions were spotted onto YPD medium containing the indicated concentrations of fumarate and/or HU, and incubated at 30\u00b0C for 2 days prior to imaging. Loss of JmjC domain-containing histone demethylase Jhd2p suppresses the sensitivity to DNA replication stress of htz1\u0394 mutants. Results Our study uncovers links between the metabolic enzyme fumarase plus the metabolite fumarate and chromatin modifications during DNA damage response in Saccharomyces cerevisiae. In mammalian cells, fumarase becomes enriched at sites of double stranded break (DSB) through interaction with the histone variant H2A.Z. At DSBs, fumarase promotes DNA repair by nonhomologous end joining (NHEJ) by local production of fumarate which in turn acts as an inhibitor of KDM2B, a H3 K36-specific histone demethylase. We have demonstrated that treatment with hydroxyurea (HU), which creates stalled replication forks by depletion of nucleotides, leads to upregulation as well as nuclear enrichment of Fum1p. We have also shown that increased cellular levels of fumarate (upon deletion of FUM1 or addition of exogenous fumarate) suppresses the sensitivity to HU in htz1\u0394 mutants in a manner that is independent of modulating nucleotide levels. In fact, fumarate confers resistance to HU in htz1\u0394 mutants by inhibition of the H3 K4-specific histone demethylase Jhd2p, and increasing H3 K4 methylation levels. Sensors and mediators of the DNA replication checkpoint were required for fumarate- dependent resistance to HU in htz1\u0394 whereas factors involved in processing of regressed replication forks were dispensable. Together, our findings imply that high cellular levels of fumarate support processing of replicative intermediates by regulation of histone methylation, thereby promoting genome integrity. Fumarase is induced and becomes enriched in the nuclear fraction upon exposure to hydroxyurea (HU) Fumarate modulates levels of JDH2-dependent H3 K4 methylation. Figure 4. Strains with indicated genotypes were analyzed in serial dilution growth assays as described in Figure 3 YKu70p is not required for suppression of sensitivity of htz1\u0394 mutants to DNA replication stress by fumarate. Figure 2. Yeast expressing Fum1-GFPp were incubated in the absence or presence of 200 mM HU at 30\u00b0C for 3 hr. Whole cell extracts (A), or nuclear fractions (B) were analyzed by immunoblotting using anti-GFP, and anti-PCNA antibodies. A representative immunoblot and fold enrichment of Fum1p from two independent experiments is shown. Levels of Fum1-GFPp were normalized to levels of PCNA (loading control), then expressed relative to signal that was observed in the absence of HU, which was set to 1. Figure 5. (A) Enhancing histone methyl", "label": "poster"}
{"text": "NuSTARConstrainstheOriginofGammaRays inRSOph Marina Orio1,2, G. Juan M. Luna3 1. U Wisconsin and INAF-Padova, 2. orio@astro.wisc.edu, 3. CONICET, Buenos Aires and Hurlingham Universities Introduction RS Oph is arguably the best known recurrent symbiotic nova. Classical and recurrent novae occur in white dwarf binaries. The outbursts are attributed to a thermonuclear runaway on the surface of the WD, that has accreted ma- terial from the binary companion. A radiation- driven wind follows, depleting the accreted enve- lope [1, 2]. The designation \u201crecurrent\u201d implies that the outburst is observed more than once over human life timescales, and in RS Oph case outbursts were recorded in 1898, 1933, 1958, 1967, 1985, and 2006. RS Oph is also a sym- biotic system, hosting a red giant M0-2 III mass donor companion [3, 4] in a binary with a 453.6 day orbital period [5]. The NuSTAR observation We obtained a Director Discretionary Time NuSTAR 40 ks exposure in the 3-79 keV range on 2021 August 17, day 10 of the outburst ( it was impossible to schedule the exposure earlier, when the source may have been harder). The X-ray \ufb02ux was expected from colliding winds, presumably the high velocity ejecta impacting the slow red giant wind. One of the most in- teresting facts of this phase is the gamma-ray \ufb02ux, measured with Fermi in the GeV range and with HESS up to tens of GeV [6]. During the NuSTAR observation, several short exposures were done with NICER. Most important, for the \ufb01rst time, a nova was observed at the same time also in gamma rays with Fermi and with Cherenkov telescopes [6]. References [1] S. Starr\ufb01eld, F. X. Timmes, C. Iliadis, W. R. Hix, W. D. Arnett, C. Meakin, and W. M. Sparks. Hy- drodynamic Studies of the Evolution of Recurrent, Symbiotic and Dwarf Novae: the White Dwarf Com- ponents are Growing in Mass. Baltic Astronomy, 21:76\u201387, January 2012. [2] William M. Wolf, Lars Bildsten, Jared Brooks, and Bill Paxton. Hydrogen Burning on Accreting White Dwarfs: Stability, Recurrent Novae, and the Post- nova Supersoft Phase. ApJ, 777(2):136, November 2013. [3] Danuta Dobrzycka, Scott J. Kenyon, Daniel Proga, Joanna Mikolajewska, and Richard A. Wade. The Hot Component of RS Ophiuchi. AJ, 111:2090, May 1996. [4] G. C. Anupama and J. Miko\u0142ajewska. Recurrent no- vae at quiescence: systems with giant secondaries. A&A, 344:177\u2013187, April 1999. [5] E. Brandi, C. Quiroga, J. Miko\u0142ajewska, O. E. Ferrer, and L. G. Garc\u00eda. Spectroscopic orbits and variations of RS Ophiuchi. A&A, 497(3):815\u2013825, April 2009. [6] H. E. S. S. Collaboration. Time-resolved hadronic particle acceleration in the recurrent nova RS Ophi- uchi. Science, 376(6588):77\u201380, April 2022. [7] Indrek Vurm and Brian D. Metzger. High-energy Emission from Nonrelativistic Radiative Shocks: Ap- plication to Gamma-Ray Novae. ApJ, 852(1):62, Jan- uary 2018. [8] Gary Wegner, Joseph P. Cassinelli, and George Wallerstein. Shockwave Models for the Outburst of the Repeating Nova, RS Ophiuchi. In Bulletin of the American Astronomical Society, volume 1, page 209, March 1969. [9] S. Orlando, J. J. Drake, and J. M. Laming. Three- dimensional modeling of the asymmetric blast wave from the 2006 outburst of RS Ophiuchi: Early X-ray emission. ApJ, 493(3):1049\u20131059, January 2009. Conclusions The low maximum temperature measured with NICER rules out that the site of the X-ray emission is the same as the site of the gamma-ray emission. In fact, the energetics of novae are such that the shock temperature may be in the hard X-ray range, but gamma rays due either to inverse Compton e\ufb00ect (leptonic mechanism) or to particle acceleration in the shock (causing pion decay; hadronic mechanism) are only associated with a very hard X-ray spectrum, with conspicuous \ufb02ux up to 80 keV. The site of the gamma-ray emission was thus optically thick even to very hard X-rays. In the 40-79 keV range, we have upper limits of 3 \u00d710\u22124 cts s\u22121 in NuSTAR. Assuming an initial X-ray \ufb02ux above 10\u22129 erg cm\u22122, consistent with Fermi ", "label": "poster"}
{"text": "RESEARCH POSTER PRESENTATION DESIGN \u00a9 2012 www.PosterPresentations.com In developing countries, Clinical Research is considered a luxurious interest with lower priority. Ongoing studies show considerable gap in responses between developed countries where most research is conducted and developing countries where most of needy population is located. Background and Significance Purpose This process proved effective and necessitated developing tools for providing more comprehensive treatment roadmaps and tracking patients\u2019 treatment milestones. Another advantage of applying the system is the improvement of medical team conduct knowing that their performance is being reviewed in what\u2019s known as Hawthorne Effect. With the establishment of first research informatics unit in the region Monitoring process became live web-based activity where performance and survival can be monitored instantaneously. Method Within five years we\u2019ve developed a model example for developing countries to improve clinical practice through integrating research methods and informatics. Dealing with all treatment regimens as research protocol with the integration of audit and feedback approach in the treatment process definitely improves treatment outcome most specifically at poorly established settings. Conclusion We demonstrate a case where practice was improved in a multi-disciplinary cancer center through setting the institution vision and objectives to be patient centered, research focused and outcome oriented. Research Clinical 2008 \u2022 Starting Protocol development and Monitoring Unit \u2022 Data collection using MS Excel 2008-2009 \u2022 Access databases (local) \u2022 Databases shared over network. 2009 \u2022 In-House development of Web-based application for electronic data capture. Each protocol is digitized. 2010 \u2022 Development of Web-based plug-in for mobile / handheld devices and real-time analysis. \u2022 Task manager \u2022 Cancer Registry 2011 \u2022 Violation Reporting / Patient safety 2012 \u2022 Joining RedCap open source Consortium \u2022 IRB submission and review online system \u2022 Research Online Training Management System. \u2022 Research and Clinical Pharmacy eLearning module 2007 \u2022 RIS: Radiology Information System. \u2022 PACS: Picture archiving and communicatio n system \u2022 LIS: Lab Information System 2007-2009 \u2022 Paper based patient charts. 2009 \u2022 Implementing Electronic medical Record System. Research Department, Children's Cancer Hospital 57357 - Egypt. Research Department, Children's Cancer Hospital 57357 - Egypt. A.S. Alfaar, M. Kamal, O. Hassanain, M. Sabry, S. Ezzat, S. Abouelnaga Advancing Clinical Oncology Practice in Developing Countries: Integrating Research Informatics for Continuous Process Improvement. Advancing Clinical Oncology Practice in Developing Countries: Integrating Research Informatics for Continuous Process Improvement. Since the development of the Protocol Monitoring unit and the Research Department, a monitoring process has been established which identified violations and deviations from the developed clinical protocols with a continuous feedback to the attending treatment and research teams i.e. treating each treatment regimen as a research protocol. 2008 Paper File 2011 Electronic research systems Pictures are graphically manipulated for protecting patients\u2019 privacy No Conflict Of Interest To Be Declared By Authors Telemedicine Live Stat\u2019s The customized treatment protocols were developed through identifying key evidence-based practices, integrating it with research questions and local clinical expertise. Cooperation with international centers like St. Jude Children\u2019s Research hospital and Dana Farber Cancer Institute as well as Children\u2019s Hospital-Boston has supported our transition into an international center through benchmarking and training. Acknowledgement This Poster is Supported by Travel Grant From ESMO Contact Us: mohamedkamalpharm@gmail.com asamir@57357research.com msabrybakry@gmail.com N.B. The team is all MDs and Pharmacists No IT members. Portal Dashboar", "label": "poster"}
{"text": "Eingangsformel Der Parlamentarische Rat hat am 23. Mai 1949 in Bonn am Rhein in \u00f6ffentlicher Sitzung festgestellt, da\u00df das am 8. Mai des Jahres 1949 vom Parlamentarischen Rat beschlossene Grundgesetz f\u00fcr die Bundesrepublik Deutschland in der Woche vom 16. bis 22. Mai 1949 durch die Volksvertretungen von mehr als Zweidritteln der beteiligten deutschen L\u00e4nder angenommen worden ist. Auf Grund dieser Feststellung hat der Parlamentarische Rat, vertreten durch seine Pr\u00e4sidenten, das Grundgesetz ausgefertigt und verk\u00fcndet. Das Grundgesetz wird hiermit gem\u00e4\u00df Artikel 145 Abs. 3 im Bundesgesetzblatt ver\u00f6ffentlicht: Pr\u00e4ambel Im Bewu\u00dftsein seiner Verantwortung vor Gott und den Menschen, von dem Willen beseelt, seine nationale und staatliche Einheit zu wahren und als gleichberechtigtes Glied in einem vereinten Europa dem Frieden der Welt zu dienen, hat sich das Deutsche Volk in den L\u00e4ndern Baden, Bayern, Bremen, Hamburg, Hessen, Niedersachsen, Nordrhein-Westfalen, Rheinland-Pfalz, Schleswig-Holstein, W\u00fcrttem- berg-Baden und W\u00fcrttemberg-Hohenzollern, um dem staatlichen Leben f\u00fcr eine \u00dcbergangs- zeit eine neue Ordnung zu geben, kraft seiner verfassungsgebenden Gewalt dieses Grund- gesetz der Bundesrepublik Deutschland beschlossen. gegeben. Es hat auch f\u00fcr jene Deutschen gehandelt, denen mitzuwirken versagt war. Das gesamte Deutsche Volk bleibt aufgefordert, Die Deutschen in den L\u00e4ndern Baden- W\u00fcrttemberg, Bayern, Berlin, Brandenburg, Bremen, Hamburg, Hessen, Mecklenburg- Vorpommern, Niedersachsen, Nordrhein- Westfalen, Rheinland-Pfalz, Saarland, Sachsen, Sachsen-Anhalt, Schleswig-Holstein und Th\u00fcringen haben in freier Selbstbestimmung die Einheit und Freiheit Deutschlands zu vollenden vollendet. Damit gilt dieses Grundgesetz f\u00fcr das gesamte Deutsche Volk. I. Die Grundrechte Artikel 1 (1) Die W\u00fcrde des Menschen ist unantastbar. Sie zu achten und zu sch\u00fctzen ist Verpflichtung aller staatlichen Gewalt. (2) Das Deutsche Volk bekennt sich darum zu unverletzlichen und unver\u00e4u\u00dferlichen Men- schenrechten als Grundlage jeder menschlichen Gemeinschaft, des Friedens und der Gerech- tigkeit in der Welt. (3) Die nachfolgenden Grundrechte binden Gesetzgebung, Verwaltung vollziehende Gewalt und Rechtsprechung als unmittelbar geltendes Recht. Artikel 2 (1) Jeder hat das Recht auf die freie Entfaltung seiner Pers\u00f6nlichkeit, soweit er nicht die Rechte anderer verletzt und nicht gegen die verfassungs- m\u00e4\u00dfige Ordnung oder das Sittengesetz verst\u00f6\u00dft. (2) Jeder hat das Recht auf Leben und k\u00f6rperliche Unversehrtheit. Die Freiheit der Person ist unverletzlich. In diese Rechte darf nur auf Grund eines Gesetzes eingegriffen werden. Artikel 3 (1) Alle Menschen sind vor dem Gesetz gleich. (2) M\u00e4nner und Frauen sind gleichberechtigt. Der Staat f\u00f6rdert die tats\u00e4chliche Durchsetzung der Gleichberechtigung von Frauen und M\u00e4n- nern und wirkt auf die Beseitigung bestehender Nachteile hin. (3) Niemand darf wegen seines Geschlechtes, seiner Abstammung, seiner Rasse, seiner Sprache, seiner Heimat und Herkunft, seines Glaubens, seiner religi\u00f6sen oder politischen An- schauungen benachteiligt oder bevorzugt wer- den. Niemand darf wegen seiner Behinderung benachteiligt werden. Artikel 4 (1) Die Freiheit des Glaubens, des Gewissens und die Freiheit des religi\u00f6sen und weltan- schaulichen Bekenntnisses sind unverletzlich. (2) Die ungest\u00f6rte Religionsaus\u00fcbung wird ge- w\u00e4hrleistet. (3) Niemand darf gegen sein Gewissen zum Kriegsdienst mit der Waffe gezwungen werden. Das N\u00e4here regelt ein Bundesgesetz. Artikel 5 (1) Jeder hat das Recht, seine Meinung in Wort, Schrift und Bild frei zu \u00e4u\u00dfern und zu verbreiten und sich aus allgemein zug\u00e4nglichen Quellen ungehindert zu unterrichten. Die Pressefreiheit und die Freiheit der Berichterstattung durch Rundfunk und Film werden gew\u00e4hrleistet. Eine Zensur findet nicht statt. (2) Diese Rechte finden ihre Schranken in den Vorschriften der allgemeinen Gesetze, den gesetzlichen Bestimmungen zum Schutze der Jugend und in dem Recht der pers\u00f6nlichen Ehre. (", "label": "poster"}
{"text": "DIE STORY IN DEN DATEN Robert K\u00f6pke IfL Leipzig Unser Use Case Im Projekt arbeitet das IfL an der Entwicklung von Visualisierungsformaten und der kritischen Analyse von Biodiversit\u00e4tsdatens\u00e4tzen. Das IfL entwickelt (raumbezogene) Visualisierungen sowie Methoden des visuellen Storytellings, um komplexe Datens\u00e4tze verst\u00e4ndlich darzustellen und unterschiedleiche Zielgruppen zu adressieren. Girlitz im Blick Seit vielen Jahren f\u00fchrt der DDA das Monitoring h\u00e4ufiger Brutv\u00f6gel durch, unterst\u00fctzt von zahlreichen geschulten Freiwilligen. Diese Story beleuchtet, wie die gesammelten Daten verarbeitet werden und welche Schl\u00fcsse daraus gezogen werden k\u00f6nnen, insbesondere im Hinblick auf den r\u00fcckl\u00e4ufigen Brutbestand des Girlitz. Sie erz\u00e4hlt von den langfristigen Erkenntnissen aus Jahrzehnten der Datenerhebung und zeigt, wie Technik die Arbeit erleichtert. Von Ruf und Realit\u00e4t Die S\u00fc\u00dfwasserfische Brachse und \u00c4sche, obwohl h\u00e4ufig vorkommend, erleben einen Bestandsr\u00fcckgang. Die l\u00e4nder\u00fcbergreifende Auswertung von Bestandsdaten, wie sie das Projekt NFDI4Biodiversity vornimmt, erm\u00f6glicht es, solche Entwicklungen fr\u00fchzeitig zu erkennen und Schutzma\u00dfnahmen einzuleiten. Diese Story zeigt am Beispiel dieser Fischarten das Potenzial der einheitlichen Datenverarbeitung f\u00fcr den Biodiversit\u00e4tsschutz. DATENGRUNDLAGE - \u0007Harmonisierter Fischmonitoring- Datensatz ZIELGRUPPE -\u0007 \u0007Wissenschaftler :innen - Fachpublikum FORSCHUNGSFRAGE Kartographische Methoden zur Visua- lisierung von Unsi- cherheiten in Vorkom- mensdaten und deren Einfluss auf Interpretation und Entscheidungsfindung. DATENGRUNDLAGE - \u0007Testfl\u00e4chen Monitoring h\u00e4ufiger Brutv\u00f6gel ZIELGRUPPE - \u0007Ausgebildete Helfer:innen - \u0007Breite \u00d6ffentlichkeit FORSCHUNGSFRAGE \u0007Wie k\u00f6nnen r\u00e4umliche Analysemethoden ein- gesetzt werden, um Muster und Trends zu identifizieren? Data Storys Die Verwendung von digitalem Storytelling, das Karten, Infografiken und Bilder einsetzt, ist eine effektive Methode, um Inhalte f\u00fcr verschiedene Zielgruppen ansprechend zu gestalten. M\u00f6glichkeiten Verbesserte Entscheidungsfindung: Erleichtern das Verst\u00e4ndnis komplexer Daten, unterst\u00fctzen so umweltpolitische und wissenschaftliche Entscheidungen. Interaktive Lernerfahrung: Multimedia-Elemente wie Videos, interaktiven Karten und Animationen k\u00f6nnen Nutzer die Daten erfahren lassen. Forschung und wissenschaftliche Analyse: Kann neue Muster und Zusammenh\u00e4nge in Biodiversit\u00e4tsdaten kommunizieren. Herausforderungen Zeitliche Dynamik: Darstellung von zeitlichen Ver\u00e4nderungen und Aktualit\u00e4t Interdisziplin\u00e4re Integration: Zusammenf\u00fchrung von Expertenwissen Darstellung von Unsicherheiten: Um Fehlinterpretationen zu vermeiden und ein realistisches Bild zu vermitteln. Dateninterpretation und -verf\u00fcgbarkeit: Sicherstellung der Genauigkeit, Aktualit\u00e4t und Vollst\u00e4ndigkeit der Daten.", "label": "poster"}
{"text": "Seminar f\u00fcr \u00c4gyptologie und Koptologie (Re-)Konstruktion der L\u00fcbecker Aegyptiaca \u2013 Didaktische Perspektiven auf gegenst\u00e4ndliche Quellen in der \u00c4gyptologie Nina Wagenknecht, M.A. E-Mail: nina.wagenknecht@stud.uni-goettingen.de Erstbetreuung: apl. Prof. Dr. Heike Sternberg-el Hotabi, Seminar f\u00fcr \u00c4gyptologie und Koptologie Zweitbetreuung: Prof. Dr. Michael Sauer, Seminar f\u00fcr Mittlere und Neuere Geschichte \u2022Thema und Zielgruppe festlegen \u2022Vermittlungsziele des Themas formulieren \u2022Objekte auf Basis des Themas ausw\u00e4hlen Thema und Zielgruppe der Ausstellung \u2022Kontextualisierung von Verwendungsweisen und Datierung der Objekte \u2022Rekonstruktion der Erwerbsumst\u00e4nde der Objekte Fachwissenschaftliche Sachanalyse \u2022Erarbeitung der Umsetzungsformate unter Einbezug von Medienwahl, - wechsel und Barrierefreiheit \u2022Ausarbeitung der digitalen Pr\u00e4sentation der Objekte in Microsoft Access Didaktische Analyse Methodisches Vorgehen Thema und Ziele der Arbeit Im Rahmen des Dissertationsvorhabens wird ein Online- Vermittlungskonzept f\u00fcr die nicht physisch ausgestellten Aegyptiaca der V\u00f6lkerkundesammlung der L\u00fcbecker Museen erarbeitet. Zentrale Ziele dabei sind: \u2022 Die \u00dcbertragung methodischer Schritte zur Vermittlung gegenst\u00e4ndlicher Quellen aus der Geschichtsdidaktik zur Erarbeitung zusammenh\u00e4ngender Lernmaterialien. \u2022 Erstellung eines Vermittlungskonzeptes thematisch ausgew\u00e4hlter Aegyptiaca unter Einbezug einer kritischen Reflexion der Sammlungsgeschichte. Materialbasis Inhalt der Sammlung: 338 Aegyptiaca (415 Objekte einschlie\u00dflich Verluste). Erwartete Ergebnisse 1. Inhaltliches Ergebnis: Ein Online-Konzept, das einen ausgew\u00e4hlten Teil des Bestandes der L\u00fcbecker Aegyptiaca der \u00d6ffentlichkeit thematisch aufbereitet zug\u00e4nglich macht und dabei die Verbindung der Objekte zur Sammlungsgeschichte der V\u00f6lkerkundesammlung kritisch einordnet. 2. Methodisches Ergebnis: Systematische Erschlie\u00dfung neuer Formate der Wissensvermittlung auf Basis der Struktur von Bestandskatalogen, die auf weitere Sammlungen \u00fcbertragen werden kann. Zeitphase Anzahl Beispiele f\u00fcr Objekte Pal\u00e4olithische Zeit 49 Flint- und Hornsteinobjekte Pr\u00e4dynastische Zeit 40 Tonkr\u00fcge, Haarnadel, Schminkpalette Fr\u00fchdynastische Zeit 9 Flintwerkzeuge Altes Reich 8 Modell-Opferteller Mittleres Reich 3 Ko\u1e25l-Gef\u00e4\u00df Neues Reich 11 Grabziegel, Umschlagtuch, Wandbruchst\u00fcck Sp\u00e4tzeit 96 Gewichtsteine, Kaurischnecken, Figur-Sockel Ptolem\u00e4ische Zeit 20 Amulette, \u00d6llampen, Ostrakon, Vogelmumie R\u00f6mische Zeit 61 W\u00fcrfel, Spinnwirtel, Schreibtafel, Brotstempel Fr\u00fchislamische Zeit 6 Koptische Textilien Unklare Datierung 12 Skarab\u00e4en, Torso einer K\u00f6nigs-Statuette 19./20./21. Jahrhundert 23 F\u00e4lschungen, Repliken Literatur Falck, Martin von. 2011. \u201eMuseologischer Anspruch und museums\u00e4gyptologische Wirklichkeit\u201c. In: Verbovsek, Alexandra, Burkhard Backes und Catherine Jones, Hrsgg. Methodik und Didaktik in der \u00c4gyptologie. Herausforderungen eines kulturwissenschaftlichen Paradigmenwechsels in den Altertumswissenschaften. \u00c4gyptologie und Kulturwissenschaft IV. M\u00fcnchen: Fink, 405\u2013422. Germer, Renate. 2018. Die alt\u00e4gyptischen Objekte der V\u00f6lkerkundesammlung der Hansestadt L\u00fcbeck: Ein Kurzkatalog zusammengestellt von Renate Germer, (Zugriff: Juli 2020). R\u00f6ttele, Hannah. 2020. \u201eObjektbegegnungen\u201c im historischen Museum: eine empirische Studie zum Wahrnehmungs- und Rezeptionsverhalten von Sch\u00fcler_innen. M\u00fcnchen: kopaed.", "label": "poster"}
{"text": "APPROACH The textile sector is undergoing a set of transformations to shift to a circular model. Within the framework of the TRICK project, an innovative approach to traceability and sustainability in textile supply chains has been developed. BACKGROUND OUTCOMES INDUSTRIAL PILOTS \u2013 CIRCULAR APPROACH The data model validation has been done through two pilots, one for the classical fashion segment and the other for the technical work-wear segment aiming to get the necessary data from a fragmented supply chain. The pilots began with the production of the goods made from virgin raw materials; the obtained garments, which usage was simulated, then were mechanically recycled. The obtained secondary raw materials include a percentage of the recycled goods; they were used to obtain garments of the same model whose characteristics were analyzed. The pilots started by an initial data gathering from the industrial users' internal system, a data validation and the mapping to the data model for its refinement. Then traceability reports were created by modeling data and reporting the product\u2019s history. The collected data was also used to perform a PEF study across the whole supply chain. CONCLUSIONS AND NEXT STEPS The holistic approach to data collection covering traceability and sustainability data allows to easily meet the requirements from new normative: it is the case of ESPR and Digital Product Passport (DPP) enforcing a sustainable approach to production and, in parallel, more efficacy of the market surveillance authorities. The next steps will be to validate TRICK efficacy in collecting faithful data to fuel the creation of digital product passport contents from the fragmented textile supply chains. On this purpose a CEN Workshop process will be launched to share and improve such contents and contribute with a public pre- standardization activity to the establishment of a framework for collecting faithful data to support the DPP statements of the fashion firms. A Traceability Report for the data collections on the events is the TRICK response to the requirements emerged from the pilot supply chains to overcome the barriers, criticalities and needs highlighted by industrial partners involved in the project. In respect of the EPCGlobal EPCIS and UNECE event models, its Enriched Event-based Model: - offers a plurality of product and lot identification methods and a more detailed process step description with a shared taxonomy of manufacturing operations - supports the collection of the events from a wide range of heterogeneous systems, covering the many tiers of the supply chain - enforces a triangle of synergies among usual daily operations, blockchain technology and business services of a traceability platform and its disclosure policies. Enhancing Traceability and Faithfulness of Sustainability Data in the Textile and Clothing Supply Chain through Blockchain and a Standard Based Enriched Event Model Gessica Ciaccio (1), Carla Fit\u00e9 Galan (2), Piero De Sabbata (1), Arianna Brutti (1) (1) Italian National Agency for New Technology, Energy and Sustainable Economic Development, ENEA, TERIN-SEN-CROSS Laboratory, via dei Mille 21, 40121, Bologna, Italy (2) Polytechnic University of Catalonia (UPC), Systems and Processes lab of the Textile Research Institute of Terrassa (INTEXTER), Carrer Colom 15, 08222, Terrassa, Spain This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 958352 Fig. 5 Representation of a circular approach of the textile pilots in the TRICK project CONTACTS Gessica Ciaccio, gessica.ciaccio@gmail.com Carla Fit\u00e9 Galan, Carla.fite@upc.edu Piero De Sabbata, piero.desabbata@gmail.com In parallel the Transparency and Sustainability Report is the core of the Transparency and Sustainability data collection. It collects all the available non- operational data about Product and Organization and shares the data groups related to sustainability with specific", "label": "poster"}
{"text": "Protect Bees, Save the Future I. Madaleno1, S. Branco1, students from 10th Grade Mechatronics1 1Externato Cooperativo da Benedita, Benedita, Portugal Abstract In this project students built a hive by adapting remote control systems for its internal environment (temperature and humidity) and external environment (door, fire, location). The solution was aimed at beekeepers, and anyone interested in getting started in the beekeeping industry. The main goals of the project were to facilitate the work of beekeepers and to improve the management, control and monitoring of hives. The solution created is feasible and satisfies the project's objectives. Keywords Automation; bees; electronics; robotics; sustainability.", "label": "poster"}
{"text": "Direct Dark Matter Search with the CRESST-III Experiment Michael Willers on behalf of the CRESST collaboration Physik-Department and Excellence Cluster Universe, Technische Universit\u00e4t M\u00fcnchen, 85748 Garching The CRESST-III Experiment The CRESST (Cryogenic Rare Event Search with Superconducting Thermometers) [1, 2] experiment aims for the direct detection of Dark Matter (DM) particles via elastic scattering off nuclei in CaWO4. CRESST-III, the current stage of the experiment, searches for low-mass (M \u227210 GeV/c2) DM particles and ultimately aims to probe the parameter space down to the neutrino \ufb02oor. The experiment is located in the Gran Sasso National Laboratory (LNGS), Italy, shielded against cosmic rays by \u223c3600 m.w.e. of rock overburden. CRESST uses a multi-element target: scintillating CaWO4 single crystals operated as cryogenic detectors. Requirements for probing low-mass DM particles: \u2022 sub-keV energy threshold due to low momentum transfer to target crystal. \u2022 Low background rate in region of interest and good background suppression capabilities. CaWO4 target crystal: \u2022 Block-shaped CaWO4 crystal (20 \u00d7 20 \u00d7 10) mm3, Mass 25g. \u2022 Sensitivity gain due to reduced heat capacity and adapted TES design. Silicon-On-Sapphire light detector: simultaneous measurement of phonon- and light-signal enables particle identi\ufb01cation and background suppression. plain CaWO4 stick holding light detector Copper housing with re\ufb02ective and scintillating inner surface (3M\u00ae Vikuiti foil [3]). Tungsten (W) TES Instrumented CaWO4 sticks (iStick) holding the CaWO4 target crystal: \u2022 events within the CaWO4 sticks are a potential back- ground for low-mass DM search. \u2022 instrumentation enables ef- \ufb01cient veto of these events. \u2022 3 iStick per module (1 read- out channel). Recent results from CRESST III phase 1 CRESST-III phase 1 started in summer of 2016 with an initial campaign to set-up and calibrate the detectors. The physics run of phase 1 started in September of 2016. \u2022 10 detector modules installed. \u2022 8 modules with TUM-grown crystals, 2 with commercial crystals. \u2022 5 modules reached / exceeded design goal of 100eV nu- clear recoil energy threshold. \u2022 Detector A has lowest threshold in CRESST-III phase 1. First analysis of detector A \u2022 Data taking period: Oct. 2016 - May 2017 \u2022 Gross exposure (before cuts): 2.39 kg days \u2022 Blind analysis with non-blind training set (20% randomly selected, excluded from DM data set). Training set data used to de\ufb01ne cuts. \u2022 Conservative analysis threshold of 100 eV. \u2022 Data quality (rate, stability, unphysical events) and coincidence (\u00b5- veto and iStick) cuts applied. 79.5% survival probability at 100eV. \u2022 Limit on DM-nucleon cross-section calculated using Yellin\u2019s optimal interval method [4] \u2192sensitivity extended to lower DM masses (lim- ited by non-\ufb02at background at low energies). The analysis of the full dataset as well as a low-threshold analysis are currently ongoing. Furthermore, the application of optimum \ufb01ltering to a stream of continuously acquired data is investigated with the goal of improving the trigger threshold of the detectors [5]. Data taken with detector A in the light yield - energy plane e\u2212/\u03b3-band recoils off oxygen recoils off tungsten dark matter acceptance region Low-energy spectrum of all events recorded with detector A CaWO4 crystal growth at TUM A high radio-purity of the CaWO4 crystals is es- sential for CRESST. In order to have full control of all crystal growth parameters, TUM has estab- lished a complete in-house CaWO4 crystal growth process [6]: \u2022 Powder production via solid state reaction or precipitation including chemical puri\ufb01cation (net reaction: CaCO3 + WO3 \u2192CaWO4 + CO2). \u2022 Crystal growth in dedicated Czochralski fur- nace. \u2022 Annealing of grown ingots in pure O2 atmo- sphere. \u2022 Cutting and polishing of target crystals. In addition, recrystallisation of grown crystals is investigated as a measure to further improve the radio-purity of the CaWO4 crystals [7, 8]. Czochralski Furnace & raw", "label": "poster"}
{"text": "Are You Catching Cosmic Rays or Just Checking Messages? Towards an Extremely Distributed Mobile Phone Cosmic Ray Observatory Carlyn Lee and Harvey Newman Division of Physics, Mathematics and Astronomy, California Institute of Technology, CA, USA Contact: Carlyn Lee Email: cblee@caltech.edu https://github.com/carlynlee/credo-api-tools/tree/playground/ References 1. Mart\u0131n Abadi, et al., TensorFlow: Large-scale machine learning on heterogeneous systems, 2015. Software available from tensorflow.org. 2. Piotr Homola, et al., Cosmic-ray extremely dis- tributed observatory. Symmetry, 2020. 3. Jennifer Ngadiuba, et al., Compressing deep neural networks on fpgas to binary and ternary precision with hls4ml. Machine Learning: Science and Technology, 2(1):015001, Dec 2020. 4. Daniel Whiteson, et al., Searching for ultra-high energy cosmic rays with smartphones, Astroparticle Physics, Volume 79, 2016, Pages 1-9, ISSN 0927-6505. This project aims to design an architecture for applying Federated Learning (FL) to the analysis of cosmic ray event data collected through the Cosmic Ray Extremely Distributed Observatory (CREDO) project. CREDO gathers data from a global network of smartphones, enabling a large-scale citizen science initiative to study cosmic rays. The traditional approach of centralizing this data raises concerns about privacy and data ownership. We explore as a potential solution, allowing decentralized training of machine learning models directly on participants\u2019 devices. We explore how FL can accommodate CREDO's requirements, such as handling heterogeneous data and robust model aggregation. We present our initial steps in designing an FL architecture tailored to the needs of the CREDO project, outline our architectural proposal, and discussing the potential benefits and the technical challenges. This sets the stage for future implementation and evaluation, aiming to enhance accountability and collaboration in scientific data analysis. Abstract Cluster Identification: Identified and visualized ten distinct clusters, each representing different events triggering the CREDO app. Device Comparison: Analysis reveals variance in detection patterns across devices, possibly indicating differences in device sensitivity or environmental conditions. Data Retrieval: Elasticsearch for query and image retrieval. Data stored as base64 encoded strings, corresponding to different devices and time frames. Image Processing: Decoded images from base64 format and resized to uniform dimensions for consistent analysis. Performed clustering based on extracted features using a pre-trained model, adapted to identify distinct patterns within the data. Cluster Visualization: Python scripts to compute and display the mean image for each cluster across multiple devices, enhancing interpretability of clustering results. Tools: Python (NumPy, Matplotlib, Pillow), ResNet50 deep learning model. q Visual analysis leveraged clustering and image processing techniques to dissect cosmic ray detection data. This approach highlighted variations across different devices and conditions, revealing possible patterns through visual data exploration. Such insights can be critical for refining detection strategies and enhancing the overall understanding of cosmic ray distributions. Future Work q Enhance Model Accuracy: Improve machine learning models and clustering precision. q Dataset Expansion: Enlarge dataset scope and integrate real-time data analysis for dynamic insights. q Federated Learning Implementation: q Local Model Training: Enable devices to train locally, sharing only model updates to minimize bandwidth use and enhance privacy. q Scalability: Use federated learning to keep data on local devices, addressing privacy concerns and managing large data volumes. q Collaborative Advancements: Combine insights across diverse devices, enhancing detection pattern accuracy and variety. q Managing asynchronous updates to models Discussion and Conclusions Objective: To analy", "label": "poster"}
{"text": "RESULTS REFERENCES Geiser, E., Walker, K. M., & Bendor, D. (2014). Global timing: a conceptual framework to investigate the neural basis of rhythm perception in humans and non-human species. Front Psychol, 5. Gorgolewski, K., Burns, C. D., Madison, C., Clark, D., Halchenko, Y. O., Waskom, M. L., & Ghosh, S. S. (2011). Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in python. Front Neuroinform, 5(3). Hanke, M., Halchenko, Y. O., Sederberg, P. B., Olivetti, E., Fr\u00fcnd, I., Rieger, J. W., ... & Pollmann, S. (2015). PyMVPA: a unifying approach to the analysis of neuroscientific data. Python in Neuroscience, 157. Kriegeskorte, N., Goebel, R., & Bandettini, P. (2006). Information-based functional brain mapping. Proc Natl Acad Sci USA, 103(10), 3863-3868. Stelzer, J., Chen, Y., & Turner, R. (2013). Statistical inference and multiple testing correction in classification-based multi-voxel pattern analysis (MVPA): random permutations and cluster size control. Neuroimage, 65, 69-82. INTRODUCTION \u2022 Humans are able to recognize a familiar rhythm, for example the rhythm of a song, independently of the tempo at which it is played. This is exemplary of the fact that auditory experiences comprise percepts of auditory Gestalt based on the rhythmic structure of sounds. \u2022 The pattern resulting from the relative temporal relationship between acoustic events is the basis for the perceptual emergence of temporal Gestalt. This Gestalt percept is invariant to the absolute temporal relationship between constituent acoustic events (Hulse et al. 1992). \u2022 It is unknown, where in the brain percepts of temporal Gestalt are generated. \u2022 A linear support vector machine (SVM) classifier was trained to differentiate activation patterns in functional Magnetic Resonance Imaging (fMRI) data to two different percepts, across different sensory constituents. \u2022 A searchlight analysis localized activation patterns specific to the temporal Gestalt. CONCLUSIONS \u2192Based on brain activation patterns, a linear SVM classifier identified which relative temporal pattern had been presented. The classifier was trained across absolute temporal patterns (tempi) of sequences. -> The classifier had identified the neural activation pattern associated with the Gestalt percept. \u2192Based on a searchlight analysis, activation patterns in the temporo-parietal junction (TPJ) (left and right hemisphere) and the inferior frontal gyrus (right hemisphere) discriminated between the two different temporally grouped percepts of temporal Gestalt. \u2192Our findings reveal for the first time that both sensory and higher cortical areas encode temporal Gestalt. \u2192The study provides an example of how we can tackle the neural basis of perceptual invariance using neuroimaging. METHODS EXPERIMENTAL SETUP \u2022 19 volunteers underwent functional neuroimaging (fMRI). Where the rhythm plays: Machine learning decodes rhythm-sensitive cortices Michael P. Notter1,2, Michael Hanke3, Micah M. Murray1,2,4,5, Eveline Geiser1,6 1The Laboratory for Investigative Neurophysiology (The LINE), Department of Radiology and Department of Clinical Neurosciences, Vaudois University Hospital Center and University of Lausanne, Lausanne, Switzerland 2Electroencephalography Brain Mapping Core, Center for Biomedical Imaging of Lausanne and Geneva, Switzerland 3Psychoinformatics lab, Institute of Psychology II, Otto-von-Guericke-University and the Center for Behavioral Brain Sciences, Magdeburg, Germany 4Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Lausanne, Switzerland 5Department of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN, USA 6McGovern Institute, Massachusetts Institute of Technology, Cambridge, MA, USA SCANNER SETUP \u2022 3T Siemens scanner; 64-channel head coil (coverage shown on the right) \u2022 TR of 2s; 365 volumes x 5 sessions; 33 slices (ascending order) PREPROCESSING \u2022 Pre-processing was done with Nipype (Gorgolewski et al., 2011): despiking (A", "label": "poster"}
{"text": "CONTACT: =ichaelOWagenpfeil IrlangenOHentreOforOUstroparticleO+hysics michaelTwagenpfeilBfauTde SEEgALSO: StudyOofO+hotonOtransportOandOSi+= inOexternalOelectricalOfieldOinOnIX; &rTO+inO\u00b0Vi)OidqOV2?6 CharacterizationgofgVUV@ sensitivegSiPMsgforgnEXO MichaelgWagenpfeilO0forOtheOnIX;Ocollaboration5 id:g#439 PhysicsgbeyondgStandardgModel? \u2022OTheOneutrinolessOdoubleObetaOdecayO 05opensOwindowOtoOphysicsObeyondOS= \u2022OUreOneutrinosO=ajoranaOparticlesN \u2022OHurrentO?\u03bd\u03b2\u03b2OsearchesOareOsensitiveO 05toOaOhalf\u2022lifeOofOaboutOv?-[OyearsO[v)O-] \u2022OnIX;OplansOtoOincreaseOsensitivityO[1] ThegnEXOgdetectorO[1)O2] \u2022OTime\u2022projection\u2022chamberO0T+H5OfilledOwithO~O6 tonsOOO 05ofOliquidOXenonO0\u00b0Xe5O\u2013OenrichedOtoO~? :OinOv1[Xe \u2022OHylindricObarrelOwithOaOdiameterOandOheightOofOvT1 m \u2022O&etectorOsetOupOinOundergroundOlabOtoOshieldOfromO 05cosmicOraysO0likelyOS/;\u00b0UG)O[??? mweT5 \u2022OSignalOdetectionOviaOchargeOreadoutOtilesO0endOcap5O 05andOVUV\u2022sensitiveOSi+=sO0innerOcylinderOsurface5 \u2022OHathodeOsetOtoO\u20226? kVOtoOproduceOaxialOdriftOfieldOO \u2022OIxtensiveOradiopurityOscreeningOtoOconstrainOG8 \u2022OQomogeneousOdetectorO#Omulti\u2022parameterOanalysis Lightgdetection \u2022OnIX;OsensitivityOdependsOonOphotonOtransportO 05efficiencyOandOphotonOdetectionOefficiency \u2022ORnsideOwallOcoveredOwithO2 m-OofOVUV\u2022sensitiveOSi+=s \u2022O&etectionOofOv]3 nmOscintillationOlightOinO\u00b0Xe \u2022O8oalqOv :OenergyOresolutionOatO\u00b5\u2022valueO0-263 keV5 \u2022OStrongOrequirementsOonOSi+=OparametersO SiPMgcharacterizationgtestgsetups \u2022OIHU+)OIrlangenO0&arkOnoise)O+&I)OVUVOreflectance5 \u2022ORQI+)OGeijingO0QVObehaviour)OVUVOreflectance5 \u2022OTzRU=7)OVancouverO0&arkOnoise)O+&I5 \u2022OUU)OUlabamaO0VUVOreflectance5 \u2022OStanfordO0+&I)OSi+=Otiles5 \u2022OU=assO0+&I)O\u00b0Xe5 VariousgSiPMs \u2022OQamamatsuOVUV1)OVUV2 \u2022O7GKO/UVO-?v[O\u00b07O#OST& 7romOleftOtoOrightq TestOsetupOatOIHU+)OtestOsetup atOStanford)OQVOsetupOatORQI+ \u2022OzecordOSi+=OdarkO 05pulsesOatO\u2022v??\u00b0H \u2022O7itOpulseOtemplateO 05toOwaveforms \u2022OUseOamplitude)O 05timestamp)OriseO#O 05fallOtimeOforOanalysis Afterpulsing \u2022O&elayedOavalanchesOcorre\u2022 05latedOtoOtheOprimaryOpulse \u2022ORmportantOnuisanceOchargeO 05contribution PDE \u2022OIfficiencyOtoOdetectOsingleO 05photons \u2022OUngle\u2022)Owavelength\u2022OandO 05biasOvoltage\u2022dependent \u2022OnIX;OrequirementsOmet nEXOgenergygresolution \u2022O&ependsOonO+&IO#OphotonO 05transportOefficiencyO0+TI5 \u2022O+lotOshowsOcaseOofO+TI%?T-OOOOO 050electronicOnoiseOneglected5 \u2022OzesolutionOgoalOachievable SiPMgHVgrobustness \u2022OSi+=sOwillObeOexposedOtoOexternalOelectricO 05fieldsOupOtoO-? kVjcmOinOnIX;OaccordingOtoO 05H;=S;\u00b0Osimulations \u2022O&etectorsOfoundOtoObeOoperationalOinOhighO 05electricOfieldsOatOcryogenicOtemperatures \u2022OGasicOparametersOunaffected\u2013O/oOdischarge \u2022O/oOdamageO\u2022OevenOonOaOmicroscopicOlevel Measuringgprocedureg@gECAP Measuringgprocedureg@gStanford \u2022OzecordO+=TOandOSi+=OpulsesOfromO-6-Hf \u2022OHalibrationOofOsingleOphotonOresponses \u2022OIxtractOchargeOratioOofOtheOdecayO 05spectrumOpeaks \u2022OTranslateOinto 05absoluteO+&I 05usingOtheO+=T 05referenceO\u00b5I \u2022OUccountOfor5cor\u2022 05relatedOnoise [v]OUgostiniOetTOalT)Ov]?6T?-~~[ [-]OIX;\u2022-??\u2022HollT)OarXivqv]?]T?3]?] [1]qOnIX;\u2022HollT)OarXivqv]v?T?6?]6 [-]qOnIX;\u2022HollT)OarXivqv3?6Tvvv2- Wb Wb e e ? 6 v? v6 -? -6 1? ? ?T- ?T2 ?T[ ?T3 v vT- +hoton detection e\ufb03ciency [:] Udditional avalanches within v\u00b5s \u00b07 Sv \u00b07 S- ST& S ?T] ?T3 ?T~ v vTv vT- vT1 vT2 ? v - 1 2 6 [ Inergy resolution [:] ;vervoltage [V] \u00b07 Sv \u00b07 S- ST& S ? v - 1 v?? v?v v?- v?1 v?2 prompt crosstalk prompt delayed crosstalk afterpulsesOand darkOnoise 0afterpulsesOand darkOnoise5Osuffering promptOcrosstalk afterpulsesOsuffering promptOcrosstalk afterpulses Hharge [pTeT] Time after trigger [ns] ? v - 1 v?? v?v v?- v?1 v?2 v?? v?v v?- /umber of events v?? v?v v?- v?1 v?2 v?6 v?[ v?] v?? v?v v?- v?1 v?2 v?6 v?[ v?] v?3 v?~ +ulse rate [Qz] Time to next pulse [ns] ]Tv V 2T[ V 1T[ V [kVjcm] I ? 6 v? v6 -? -6 1? 8ain \u03b7 ?T3 ?T36 ?T~ ?T~6 v vT?6 vTv vTv6 vT- 7GK\u2022z8G 7GK\u2022lowOfield QamamatsuOVUV1 relativeOSi+=O8ain [kVjcm] I ? 6 v? v6 -? -6 1? H/ + \u03b7 ?T3 ?T36 ?T~ ?T~6 v vT?6 vTv vTv6 vT- 7GK\u2022z8G 7GK\u2022lowOfield QamamatsuOVU", "label": "poster"}
{"text": "Materials and Methods Sarah K . Morris1\u2020*; Oscar A. P\u00e9rez-Escobar1,2\u2020*; Bente B. Klitg\u00e5rd1; Alexandre Antonelli1,2; Alejandro Zuluaga3; Monica Carlsen4; Eve J. Lucas1; Simon Mayo1; Anna Haigh1; Steven Dodsworth5; Olivier Maurin1; Grace Brewer1; Robyn Cowan1; Ilia J. Leitch1; Felix Forest1; William J. Baker1 The origin and diversification of the hyper-diverse flora in the Choc\u00f3 biogeographic region Objectives Anthurium obtusilobum Silica-gel dried leaf fragments 13 outgroup 27 Anthurium DNA extraction, shearing, library preparation, pooling, hybridization and sequencing as described in Johnson et al. (2018) with Angiosperm353 bait kit HybPiper v 1.3.1 (with Spathiphyllum kochii reference) skimmed plastid genome data (39 Anthurium) multiple sequence alignment use full genomic alignment to constrain combined alignment for Maximum Likelihood tree Secondary calibration age of Pothoideae13 Petrocardium cerrejonense (55.8 Myr)8 divergence time estimation with BEAST v2.0 geographic occurrence data from GBIF ancestral range estimation comparing biogeographical models with R-package BioGeoBEARS v0.2.1 1Royal Botanic Gardens, Kew. TW9 3AE, London, UK 2Gothenburg Global Biodiversity Centre, Sweden 3Universidad del Valle, Colombia 4Missouri Botanical Garden, USA 5University of Bedfordshire, Luton, UK \u2020these authors contributed equally to this study *corresponding authors: o.perez-escobar@kew.org, s.morris@kew.org Alwyn H. Gentry (Annals of the Missouri Botanical Garden, 1996) Geographic extension of the Choc\u00f3 biogeographical region in Central and South America12 and its compound geological origin14 Extract loci from genomic alignments that match Sanger sequences from Carlsen & Croat (2013) \uf0a7Angiosperm 353 kit successfully enriched 50-333 nuclear genes (& recovered 93 plastid genes) \uf0a7species-tree coalescence analyses revealed extensive incongruence near the MRCA of Anthurium \uf0e0the timing and origin of the MRCA of Anthurium remains unclear \uf0a7multiple migrations into Choc\u00f3: \uf0a73 at ~9 Mya from Central America \uf0a71 at ~5 Mya from Amazonia \uf0a7multiple recent migrations within 1 My from Central America and northern Andes Were Gentry\u2019s ideas about the mode and tempo of plant evolution into the Choc\u00f3 correct? \uf0a7Chocoan flora is likely older than Gentry assumed (perhaps late Miocene) \uf0a7migrations occurred after rapid mountain building had begun in the northern Andes \uf0e0allopatric speciation due to Andean uplift unlikely \uf0a7origin of Chocoan flora from Central America and northern Andes is supported \uf0a7migrations split between 9 Mya and < 1 Mya, suggesting a burst of migration after the closure of the CAS and again more recently Gentry believed the habit type, dispersal system and pollination syndrome of the Chocoan flora allowed for rapid speciation of endemics7: \uf0a7shorter generation time of shrubby and herbaceous groups \uf0a7bird and mammal (more localized) dispersal \uf0a7specific pollinator relationships \uf0a7To investigate these biotic factors, we are conducting similar genomic studies of other representative groups, including Blakea (Melastomataceae) and Neotropical orchids14 key geologic events in mid-late Miocene: 1. accretion of the Choc\u00f3 Block4 2. Northern Andean orogeny9 3. closure of the Central American Seaway (CAS)10 The Choc\u00f3 Introduction Gentry from available floristic, geological and palynological data in the 80s: Chocoan flora \uf0e0originated in the mid- Pleistocene from Amazonian lineages which migrated around the northern Andes, through southern Central America 6 \u201cthe historical accident of the Andean uplift, with the concomitant opportunity for explosive speciation among certain taxa \u2026 may largely explain the \u201cexcess\u201d plant species diversity of the Neotropics\u201d 5 Test Gentry\u2019s hypothesis with genomic data of Anthurium using phylogeny reconstruction, molecular dating and ancestral area estimation We expect to see: \uf0a7a MRCA for the Anthurium lineage in Amazonia \uf0a7a MRCA of Chocoan clades in the northern Andes and Central America \uf0a7migration into the Choc\u00f3 in the Pleis", "label": "poster"}
{"text": "State-independent wind Wind-related features Observing a black hole transient Javier S\u00e1nchez-Sierras E-mail: javisansie@gmail.com Instituto de Astrof\u00edsica de Canarias Wind-type outflows from the black hole X-ray binary MAXI J1820+070: the near infrared view SOFT HARD X-ray winds (expected) Optical winds Near-infrared winds MAXI J1820+070 is a low-mass X-ray binary (LMXB) with a black hole of ~8M\u2609located very nearby, at only 3kpc. It was discovered during a bright outburst of the source in 2018, which showed a standard evolution in the Hardness-Intensity Diagram (see image below), passing through the main accretion states: hard and soft. THE SPECTRA We obtained 8 spectra using VLT/X-shooter, a spectrograph with a wide spectral range from optical to near-infrared (3000 \u00c5 \u2013 24750 \u00c5). These observations cover the different accretion states (soft, red; intermediate, green; hard, blue). Optical winds have been observed during the bright-hard state, which is consistent with previous studies in other LMXBs, such as V404Cyg, V4641Sgr or GRS 1716-249. The optical winds discovered during the hard state were observed in some optical lines, such as Ha or HeI-5876\u00c5. The wind-related features observed include P-Cygni profiles and broad emission line wings, and they showed velocities of 1200-1800 km/s. NEAR-INFRARED SPECTRAL RANGE We analysed several near-infrared lines during the hard state and found wind-related features such as blue- shifted absorptions and broad emission line wings (see image above). These features showed similar kinetic properties to the optical ones. During the soft state, these wind features disappear in optical lines but remain visible in the near-infrared spectra. The presence of wind-related features in near-infrared lines during both hard and soft accretion states, with similar kinetic properties to the hard state optical ones, suggests that they are tracing the same wind. This state-independent wind changes its visibility depending on the conditions of the material (i.e. temperature, ionization level, ...). This idea can be seen in the sketch above, which shows the presence of the wind during the 2018 outburst of MAXI J1820+070. This represents one more step to complete the picture of winds in X-ray binary outbursts. S\u00e1nchez-Sierras J. 1,2, Mu\u00f1oz-Darias T. 1,2 1 Instituto de Astrof\u00edsica de Canarias (Tenerife, Spain), 2 Universidad de La Laguna (Tenerife, Spain) Based on paper: S\u00e1nchez-Sierras & Mu\u00f1oz-Darias, 2020, A&A 640 L3", "label": "poster"}
{"text": "SAW 2024 \u2013 Seeing and Ac\u019fng Workshop: Func\u019fonal and Neural Perspec\u019fves Poster Session 1 \u2014 September 27, Friday 1 \u2013 Visually guided ac\u019fons survive bilateral lesions of the occipitotemporal cortex: evidence from behavioural and tractography Authors: Ana C. Torres Cresto, Marine Keime, Alessandro Vinciarelli, Melvyn A Goodale, Jody C. Culham, Cassandra Sampaio-Bap\u019fsta, Monika Harvey 2 \u2013 Evolu\u019fonary approaches for audio-visual associa\u019fons Authors: Ana Rodrigues, Am\u00edlcar Cardoso, Penousal Machado 3 \u2013 Seeing speech: Probing the cerebral mechanisms of Cued Speech percep\u019fon Authors: Annahita Sarr\u00e9, Laurent Cohen 4 \u2013 Using ultra-high resolu\u019fon MRI to uncover the underlying microstructural mechanisms of structural plas\u019fcity in blind humans Authors: Anna-Lena Stroh, Daniel Haenelt, Luke J. Edwards, Fakhereh Movahedian A\u01a9ar, Kerrin J. Pine, Robert Trampel, Marcin Szwed, Nikolaus Weiskopf 5 \u2013 Di\ufb00eren\u019fal modula\u019fon of serial dependence by ac\u019fon percep\u019fon integra\u019fon in au\u019fsm spectrum traits in a dynamic VR task Authors: Antonella Pom\u00e8, Michael Wiesing, Rebecca S\u00fcther, Eckart Zimmermann 6 \u2013 Does Observing Bodily Movement Contribute to Developing Goal Comprehension? Authors: Ben-Ami Shlomit, Verma Dhun, Lall Naviya, Ganesh Suma Ralekar Chetan, Gilad- Gutnick Sharon, Sinha Pawan 7 \u2013 Touch localiza\u019fon a\u014cer nerve repair: Longitudinal measures reveal high individual variability Authors: Benjamin Govier, Mar\u019fn Weber, Andrew Marshall, Obi Onyekwelu, Louise Booth, Edwin Jesudason, Vivien Lees, Ken Valyear 8 \u2013 Func\u019fonal organisa\u019fon of sensorimotor regions in people with congenital facial paralysis (Moebius Syndrome) Authors: Ceren Ba\u01a9al, Emmanuelle Bellot, Benoit Herman, Iqra Shahzad, Moritz Wurm, Olivier Collignon, Gilles Vannuscorps 9 \u2013 Can the dimensionality crossing phenomenon partly explain the large sex di\ufb00erence in the mental rota\u019fon test? Authors: Daniela E. Aguilar Ramirez, Stephanie Chu, Claudia L. Gonzalez 10 \u2013 Reach adjustment and target selec\u019fon begin within 80ms Authors: David Y. Mekhaiel, Melvyn A. Goodale, Brian D. Corneil 11 \u2013 Comparing object topography in visual cortex and ar\u019f\ufb01cial neural networks Authors: Davide Cor\u019fnovis, Bracci Stefania 12 \u2013 Reward as a facet of word meaning Authors: Doina-Irina Giurgea, Penny M. Pexman, Richard J. Binney 13 \u2013 Distributed high-level processing supports the emo\u019fonal assessment of complex social scenes (human brain and AI) Authors: Elahe Yargholi, Laurent Mertens, Joost Vennekens, Jan Van den Stock, Hans Op de Beeck 14 \u2013 Changes in connec\u019fvity between \u2018higher order\u2019 perceptual areas in apraxia a\u014cer stroke Authors: Elisabeth Rounis Zuo Zhang, Ajay Halai, Gloria Pizzamiglio, Ma\u01a9 Lambon Ralph 15 \u2013 Localising touch on the hand: Revealing systema\u019fc varia\u019fons in performance and context-dependent direc\u019fonal biases. Authors: Elsie Harvey Pearce, Ronan Timircan, Mar\u019fn Weber, Kenneth Valyear 16 \u2013 Inves\u019fga\u019fng the func\u019fons underlying short-term memory conjunc\u019fve binding through the study of aphantasia Authors: Emma Delhaye, Pauline Fritz, Charlo\u01a9e Mar\u019fal, Chris\u019fne Bas\u019fn 17 \u2013 Tes\u019fng humans and machines on the animate-inanimate dis\u019fnc\u019fon for ambiguous visual objects Authors: Farzad Rostami-Ghahfarokhi, C\u00e9line Spriet, Hans Op De Beeck, Jean-Remy Hochmann, Liuba Papeo 18 \u2013 A\u01a9en\u019fon to Ac\u019fons Authors: Federica Danaj, Lena Gessele, Jens Schwarzbach, Paul Downing, Angelika Lingnau 19 \u2013 Connec\u019fng the dots: similar visual reading acquisi\u019fon for Braille or line junc\u019fons Authors: Filippo Cerpelloni, Olivier Collignon, Hans Op de Beeck 20 \u2013 Reweigh\u019fng of Visual Depth Cues through Dynamic Interac\u019fon with Con\ufb02ic\u019fng S\u019fmuli Authors: Francesca Peveri, Andrea Canessa, Silvio P. Saba\u019fni 21 \u2013 Does unisensory object categorisa\u019fon improve following mul\u019fsensory category training? Authors: Grace A. Gabriel, Fiona N. Newell 22 \u2013 Interac\u019fons of Visual and Motor Plas\u019fcity in Adults Authors: Izel D. Sari, Claudia Lunghi 23 \u2013 A specialized mental resource for intui\u019fve physics Authors: Jason Fischer, Alex Mitko 24 \u2013 Ultrafast RS fMRI unveils", "label": "poster"}
{"text": "Health-related quality of life of people attending screening for diabetic retinopathy within a trial setting CJ Sampson,1\u2020 M James,1 D Van Eker,2 D Szmyt,2 SP Harding3 \u2020chris.sampson@nottingham.ac.uk 1University of Nottingham | 2Royal Liverpool University Hospital | 3University of Liverpool Introduction Background \u2022 DR associated with lower health-related quality of life (HRQoL) \u2022 Economic evaluations tend to base outcomes on visual acuity. Aims \u2022 Estimate generic HRQoL for a cross-section of attenders within the UK screening programme \u2022 Inform calculation of quality-adjusted life years (QALYs) for model-based economic evaluation. Methods: the sample \u25b6874 people from 7 screening centres in Liverpool, UK \u25b6Baseline trial data from the ISDR study \u25b6Matched screening outcome data R0 No retinopathy R1 Background retinopathy (in at least one eye) Methods: outcome measures \u25b6Two widely-used generic descriptors of HRQoL. \u25b6Both can be used to calculate QALYs. \u25b6Together provide 5 ways to measure HRQoL. EQ-5D-5L Dimensions 5 dimensions reported from 1 (no problems) to 5 (extreme problems) Index score Weighted score based on health state preferences elicited from the UK general public, used to calculate QALYs EQ-VAS A visual analogue scale from 0 (\u201cThe worst health you can imagine\u201d) to 100 (\u201cThe best health you can imagine\u201d) HUI3 Dimensions 8 dimensions (including \u2018vision\u2019) scored from 1 (no problems) to 5 or 6 (severe functional limitations) Index score Multi-attribute utility function, to calculate QALYs Results: full sample \u25b6840 (96%) fully completed EQ-5D-5L \u25b6738 (84%) fully completed HUI3 \u25b6Mean EQ-5D-5L index score was 0.777 \u25b6Mean HUI3 index score was 0.707 Table: EQ-5D-5L: distribution of responses 1 2 3 4 5 Mobility 52% 15% 17% 15% 0% Self-care 76% 10% 10% 4% 1% Usual activities 57% 15% 15% 10% 3% Pain/discomfort 43% 20% 20% 14% 4% Anxiety/depression 67% 14% 12% 5% 1% Table: HUI3: distribution of responses 1 2 3 4 5 6 Vision 31% 63% 3% 2% 2% 1% Hearing 78% 11% 7% 3% 1% 0% Speech 93% 4% 2% 0% 0% \u2014 Ambulation 63% 18% 11% 5% 2% 0% Dexterity 81% 14% 2% 2% 1% 0% Emotion 66% 21% 9% 3% 1% \u2014 Cognition 68% 8% 18% 4% 2% 0% Pain 40% 26% 15% 12% 7% \u2014 \u25b6Dimensions with \u226520% of responses are highlighted Results: R1 vs R0 \u25b6R1 screening outcome associated with lower HRQoL on average than R0 EQ-5D-5L 0.762 vs 0.776 HUI3 0.660 vs 0.713 (p=0.03) EQ-VAS: How do EASDec delegates compare? \u25b6The left side of the scale shows the distribution in our sample. \u25b6Place a sticker on the right according to how good or bad your health is TODAY. The best health you can imagine 100 0 The worst health you can imagine Discussion \u25b6HUI3 recognised as being more sensitive to visual impairment, but may require trade-off with data quality \u2022 Lower mean HUI3 index score may reflect inclusion of sensory domains \u25b6Economic modelling studies that treat R1 and R0 as homogeneous may give biased results \u25b6We cannot determine whether the difference in HRQoL between R1 and R0 is because of retinopathy level Conclusions \u25b6DR screening attendees have an impaired HRQoL compared with the general population \u25b6People with background retinopathy have lower health-related quality of life than people with no retinopathy \u2022 Statistically significant difference of 0.053 in mean HUI3 index score \u25b6HUI3 is associated with poorer completion rates \u2022 Greatest missingness on \u2018vision\u2019 domain \u25b6www.isdrproject.co.uk \u25b6Twitter @ISDRstudy Download this poster DOI: 10.6084/m9.figshare.3443705 This poster presents independent research funded by the NIHR under the Programme Grants for Applied Research programme (RP-PG-1210-12016). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Heath.", "label": "poster"}
{"text": "Altered Physiological Conditions Lead To Antibiotic Persistence In Vibrio Cholerae. Shridhar Paranjape*, Shashidhar R. Bhabha Atomic Research Centre, Mumbai, India. shridharsonda@gmail.com Introduction The physiological heterogeneity of a bacterial population is a complex phenomenon. The asymmetric cell division and asynchronous metabolic activities result in the population with age gradients. The persister cells are the transiently dormant cells which survive prolonged exposure to bactericidal antibiotics. We hypothesized that the changes in nutrient levels, which are common in the environment, can cause significant changes in tolerance to antibiotics. Here, an attempt has been made to disturb the cell physiology using different strategies to alter the antibiotic persistence. Methods \u2022 Antibiotics used: Ciprofloxacin, Ampicillin, Carbinicillin, Kanamycin, Erythromycin, Gentamycin and Chloramphenicol. Data 1. Mulcahy LR, Burns JL, Lory S, Lewis K. 2010 Dec;192(23):6191\u20139. 2. Harms A, Maisonneuve E, Gerdes K. Science. 2016 Dec 16;354(6318). pii: aaf4268. 3. Sharma B, Brown AV, Matluck NE, Hu LT, Lewis K. 2015 May 26;AAC.00864-15. 4. Balaban NQ, Merrin J, Chait R, Kowalik L, Leibler S. 2004 Sep 10;305(5690):1622\u2013 5. 5. Fauvart, Maarten & De Groote, Valerie & Michiels, Jan. (2011). 60. 699-709. 10.1099/jmm.0.030932-0. Results 1. The V. cholerae forms persister subpopulations , when challenged with ampicillin and ciprofloxacin. (Fig. 1) 2. The persistence varies with the media type, in the order of decreasing persistence: TSB > LB > M9 > APW. (Table 1) 3. The reduced respiration is key to successful persistence. (Table 2) 4. The V. cholerae was sensitive to inhibition of protein synthesis with no persistence formation. (Table 3) \u2022 The present study reveals the complex responses of cell population under antibiotic treatment. \u2022 This research could be the beginning of phylogenic clad specific studies of persister cell formation with respect to cell physiology. \u2022 The persistence may represent a unique physiological state amongst the various physiological states in a bacterial population. \u2013 Single cell based studies may reveal more about the molecular mechanisms underlying persister physiological states. References Fig. 1.Effect of different antibiotics on exponential culture of V. cholerae Table 1. Persistence as a function of media type and nutrient. Table 2. Persistence as a function of respiration Table 3. Persistence as a function of protein synthesis Discussion Fauvart et al.(2011) 0 1 2 3 4 5 6 7 8 9 10 0 2 4 6 8 10 Log CFU ml-1 Time (hours) V. cholerae Ciprofloxacin Kanamycin Ampicillin Persister frequency Media V. Cholerae E. coli Luria Bertani broth 0.1 0.1 Tryptone soya broth 10 0.1 Alkaline peptone water 0.001 NA M9 minimal media 0.01 0.01 Antibiotic V. cholerae E. coli Aerobic An- aerobic ATP - uncoupler Aerobic An- aerobic ATP- uncoupler Ampicillin 1 10 10 0.01 100 100 Ciprofloxacin 0.1 100 10 0.01 10 100 Kanamycin 0 0.01 0 0.1 10 10 Antibiotic V. cholerae E. coli Kanamycin 0 0.1 Chloramphenicol 0 1.0 Erythromycin 0 0.1 Gentamycin 0 0.1", "label": "poster"}
{"text": "the problem methodology findings on the one hand 1st possible consequence To assess the evaluation process of professional doctorate proposals, three types of analysis were performed: Even though they were not clear before, CAPES had some expectations from proposals. From the evaluation reports of the 105 projects which were not approved, we see examples of such unful\ufb01lled expectations: According to CAPES, without previously establishing the criteria and indicators for the accreditation of professional doctorates, they expected: In spite of the lack of pre-established criteria and indicators for the accreditation process, this research showed that CAPES\u2019 evaluation was well conducted and that expectations for the approval of PrD courses are consistent throughout \ufb01elds. Expectations Reality on the other hand \u2022 Without criteria or indicators for PrD, proposals were: \u2022 Too conservative and did not innovate from this \u201cfreedom\u201d; \u2022 Inspired by academic doctorates (without the required professional nature) or professional master\u2019s (not advanced enough). \u2022 Without ground-breaking proposals at hand, the accreditation process could only focus on the viability of the proposed courses, resulting in low approval rates. \u2022 The lack of pre-established criteria and indicators did not mean a lack of expectations. Several proposals were weakened because of that. Andr\u00e9 Brasil a.l.brasil@cwts.leidenuniv.nl Centre for Science and Technology Studies Leiden University, The Netherlands September, 2019 Accreditation of Graduate Courses in Brazil Analysing the Evaluation of the First Proposals of Professional Doctorates in the Country http://bit.ly/2Z6KqJp Approval rates are strikingly different between academic and professional proposals, with fewer accredited courses in the second modality. Proposals Approved Not approved 43.9% 60.0% 77.8% 78.2% Academic Doctorate (PhD) Academic Master\u2019s Professional Doctorate (PrD) Professional Master\u2019s 56,1% 40.0% 22.2% 21.8% Graduate education is responsible for over 80% of S&T research in Brazil Professional Master\u2019s were authorised in 1998 and Doctorates in 2017/2018 135 professional doctorate (PrD) proposals were submitted in the \ufb01rst evaluation cycle There are over 6500 graduate courses in the country today Course accreditation is compulsory, conducted by a federal agency (CAPES) No criteria or indicators were stablished before submissions Could an evaluation process without previously defined criteria and indicators work? NOT WITHOUT CONSEQUENCES! http://bit.ly/2M9awpk Get the full paper, this poster, and more at: Regulations and guideline documents related to the accreditation of graduate courses were investigated. Documental The evaluation results of 1404 accreditation proposals were analysed across distinct \ufb01elds, levels and modalities. Statistical The reports on the assessment of the 135 professional doctorate proposals were individually analysed in order to identify the existence of coherent criteria and indicators. Qualitative 1 2 3 4 5 6 UNRESTRICTED Proponents would not be limited by pre-established concepts of what a professional doctorate should be. INNOVATION They would innovate, designing ground-breaking graduate programs, which could inspire evaluators. INSPIRATION Evaluation committees would build criteria and indicators based on proposals and previous experience. GUIDELINES The evaluation effort would lead to proper guideline documents to support future submissions. 1 2 3 4 INSTITUTIONAL SUPPORT Expected: projects should include evidence of integration with productive sector. Reality: most projects were successful in that, but some failed to show these partnerships. 73% positive PROPOSAL Expected: projects should have an applied science design at a doctoral level. Reality: most proposals were either too academic or were closer to a master\u2019s level. FACULTY (Profile) Expected: faculty could include experienced professionals from the productive sector. Reality: faculty pro\ufb01le was almost exclusively", "label": "poster"}
{"text": "Cuscuta campestris Cuscut\u0103 mare Familia Convolvulaceae, Clasa Magnoliopsida Plant\u0103 erbacee anual\u0103, parazit\u0103, lipsit\u0103 de cloro\ufb01l\u0103, f\u0103r\u0103 frunze, cu tulpini volubile, foarte rami\ufb01cate, galbene-portocalii, ce formeaz\u0103 prin \u00eempletire \u0219i r\u0103sucire plase laxe ce se \u00eentind ca o p\u00e2nz\u0103 pe suprafe\u021be de mai mul\u021bi metri p\u0103tra\u021bi. Florile sunt nemirositoare, dispuse c\u00e2te 10-30 \u00eentr-un glomerul. Corol\u0103 campanulat\u0103, cu lobii triunghiulari, acu\u021bi. Fructul este capsul\u0103 globuloas\u0103, u\u0219or turtit\u0103, cu 2-4 semin\u021be brune, ovoidale, cu suprafa\u021ba neregulat\u0103. Foto credit: https://www.invasive.org/search/action.cfm?q=cuscuta+campestris Flori Fruct 1 Semin\u021be", "label": "poster"}
{"text": "SITool (v1.0) An evaluation tool for large-scale sea ice model simulation Xia Lin, Fran\u00e7ois Massonnet, Thierry Fichefet, and Martin Vancoppenolle 1) Absolute errors at each grid cell (1980-2007) Mean: ->monthly mean over 12 months (Meandiff) Interannual variability/trend: monthly anomalies -> standard deviation (SDdiff)/linear regression (Trenddiff) 2) Average spatially weighted by grid cell areas 3) Scaled by typical errors (absolute difference between two observations) Meandiff = \u2211!\"# !\"#$ \u2211&\"# &\"' ()* !,& ,(#* !,& \u00d7.& \u2211&\"# &\"' .& \u00d7 #! \u2211!\"# !\"#$ #! (1) SDdiff = \u2211&\"# &\"' $%(')&(')* & )($%('#&('#* & ) \u00d7*& \u2211&\"# &\"' *& (2) Trenddiff = \u2211!\"# !\"$ \"#$%&((%!)(%& ! ))\"#$%&((#!)(#& ! ) \u00d7,! \u2211!\"# !\"$ ,! (3) \ud835\udc5b(months); \ud835\udc56(grid cells); \ud835\udc36/0, \ud835\udc3610/ \ud835\udc36/, \ud835\udc361(two monthly mean/monthly ice concentration); A (grid cell area); D (days in each month). Sea ice plays a fundamental role in the polar environment, by influencing air\u2013ice and ice\u2013sea exchange, atmospheric and oceanic processes, and climate change. Large inter-model spread exists in the performance of sea ice simulations. Systematic projections and evaluations on sea ice simulations are needed. Want to quantify the bias in sea ice simulations? Want to track performance across different model versions? Try SITool released on the GitHub (open-access): https://github.com/XiaLinUCL/Sea-Ice-Evaluation-Tool A performance metrics and diagnostics tool developed to evaluate the skill of Arctic and Antarctic model reconstructions of sea ice concentration, extent, edge location, drift, thickness, and snow depth. 1 The concept of the SITool 3 Application to CMIP6 OMIP 2 The methods in SITool Find more information on the sea ice edge location, drift, thickness and snow depth in Lin et al. (2021). Xia Lin, Fran\u00e7ois Massonnet, Thierry Fichefet and Martin Vancoppenolle, SITool (v1.0) \u2013 a new evaluation tool for large-scale sea ice simulations: application to CMIP6 OMIP. Geosci. Model Dev., 14, 1\u201324, 2021. SITool provides metrics and diagnostic maps 3.1 Sea ice concentration 3.2 Sea ice extent Any comments/questions? Get in touch! xia.lin@uclouvain.be Metrics: Lower values -> better skill 1) Model errors >> observational uncertainty 2) Improved simulations from OMIP1 (CORE-II) to OMIP2 (JRA55-do) 3) Lower skill on the ice concentration variability Ice extent: total area of grid cells with the ice concentration above 15% -negative ice extent biases in the summer reduced in OMIP2 Model mean ice extent monthly anomalies; -large bias reduced under OMIP2 Diagnostic maps: Reduced negative bias of summer Arctic ice concentration in OMIP2", "label": "poster"}
{"text": "1) Background \u2022 Many people struggle to manage indulgences in our current \u2018obesogenic\u2019 environment (Kruger et al. 2004) \u2022 Results of our previous qualitative study showed that one of the strategies to reduce intake of tempting foods is to plan meals in advance (Gatzemeier et al. under review) \u2022 Planned indulgences increase motivation to continue with goal pursuit (e.g. following a diet to lose weight) (Coelho do Vale et al. 2016) \u2022 High restrained eating is associated with lower food intake (Olea L\u00f3pez et al. 2016) Jennifer Gatzemeier, Menna Price, Laura Wilkinson, Michelle Lee Department of Psychology, Swansea University, UK. Rigid and flexible restraint moderates a relationship between a future eating prime and food intake Rigid and flexible restraint moderates a relationship between a future eating prime and food intake Coelho do Vale, R., et al. (2016). \"The benefits of behaving badly on occasion: Successful regulation by planned hedonic deviations.\" Journal of Consumer Psychology 26(1): 17-28. Gatzemeier, J., et al. (2018). \u201cUnderstanding everyday strategies used to manage indulgent food consumption: a mixed-methods design.\u201d Manuscript submitted for publication. Kruger, J., et al. (2004). \"Attempting to lose weight: Specific practices among U.S. adults.\" American Journal of Preventive Medicine 26(5): 402-406. Olea L\u00f3pez, A. L. and L. Johnson (2016). \"Associations between Restrained Eating and the Size and Frequency of Overall Intake, Meal, Snack and Drink Occasions in the UK Adult National Diet and Nutrition Survey.\" PLoS One 11(5): e0156320. Van Strien, T., et al. (1986). \"The Dutch Eating Behavior Questionnaire (DEBQ) for Assessment of Restrained Emotional, and External Eating Behavior.\" International Journal of Eating Disorders 5(2): 295-315. Westenhoefer, J., et al. (1999). \"Validation of the flexible and rigid control dimensions of dietary restraint.\" Int J Eat Disord 26(1): 53-64. 3) Methods 3) Methods \u2022 Procedure a) Priming: Intervention: writing down near future eating plans Control: writing down near future non-eating plans (e.g. going to the cinema) b) Presentation of taste test: c) Questionnaires: DEBQ (Van Strien, Frijters et al. 1986) Rigid and flexible restraint (Westenhoefer, Stunkard et al. 1999) Question about trait tendency to plan indulgences \u2022 Analysis: Moderation analysis with SPSS PROCESS macro \u2022 Registered at OSF (https://osf.io/pydvz) 5) Conclusions 5) Conclusions \u2022 Flexible and rigid restraint is indeed moderating the association between condition and intake: The intervention condition had a significantly higher consumption compared to the control condition, but only in low rigid and flexible restraint \u2022 For low restrained eaters thinking about future eating plans might have enhanced attention to the snacks and therefore increased wanting \u2022 High restraint eaters exert a high level of cognitive control to maintain restraint. This might have led to an insensitivity to the priming \u2022 Further research is needed to understand the underlying mechanism of the observed interactions and the difference between low and high restrained eaters 2) Research Questions 2) Research Questions \u2022 We hypothesis that the trait tendencies to plan indulgences moderate the association between a future eating prime and food intake. Participants with the trait tendencies to plan indulgences consume less after a future eating prime \u2022 We are interested if restraint is moderating the relationship between the priming and intake. Contact: Jennifer Gatzemeier jennifer.gatzemeier@swansea.ac.uk Department of Psychology, Swansea University, Singleton Park, Swansea, SA2 8PP, UK Tel: +44 (0) 1792 295279 Swansea Nutrition, Appetite and Cognition group a) Priming b) Taste test c) Questionnaires 1. Minstrels (Mars, UK) 2. Bitsa Wispa (Cadbury, Mondelez, Birmingham, UK) 3. Haribo Star Mix (HARIBO Dunhills, Pontefract, UK) 4. Pringles Original (Wimble Manufacturing Belgium, Mechelen, Belgium) 5. Salted Popcorn (Tesco Stores Ltd., Cheshunt, U", "label": "poster"}
{"text": "Reactor Neutrino Anomalies and Possible Solutions Yu-Feng Li* Institute of High Energy Physics, Beijing, China *corresponding author: liyufeng@ihep.ac.cn \uf0d8Reactor neutrinos (electron antineutrinos) are produced from beta decays of the neutron-rich fission products, and are detected via the inverse beta decay (IBD) process. \uf0d8Reactor experiments have shown anomalous results for both IBD rate (left plot) and spectrum (right plot) measurements \uf0d8Reactor rate anomaly: measured IBD yields are smaller than model predictions by around 6%. \uf0d8Reactor spectrum anomaly: there is a bump at around 5 MeV when comparing the measured and predicted spectra. \uf0d8How to solve these reactor anomalies is an intensively discussed topic in nuclear and particle physics community. 1. Reactor neutrino anomalies 3. Ab initial method \uf0d8Using the reactor rates data and fuel evolution data: 2. Data-driven method \uf0d8Reactor rates tend to favor equal suppression of the 235U and 239Pu fluxes (oscillation), while (DYB & RENO) fuel evolution data favor the suppression of 235U. \uf0d8Regarding all hybrid hypotheses: a) a deficit for the 235U flux is always obtained; b) oscillation-including hypothesis is favored over the oscillation-excluding one: moderately at 1-2\u03c3 5. Conversion method Giunti et al., JHEP 10 (2017) 143 4. Beta decay at KATRIN 6. Conclusion \uf0d8Reactor rate/spectrum anomalies are interesting topics in particle and nuclear physics, and awaiting satisfactory solutions. \uf0d8Data-driven method always favors a suppression of the 235U flux, while KATRIN can provide independent tests. \uf0d8Both the ab initial and conversion calculations need to be improved in many aspects (database, fission yield and single spectrum, etc.). \uf0d8Accurate reactor rate and spectrum predictions are important for future reactor experiments (i.e., JUNO). Giunti et al., Phys. Rev.D 99 (2019) 073005 \uf0d8Ab initial model for the reactor neutrino flux: summation of each beta decay branches using the nuclear database for the fission and decay information \uf0d8Possible problems: the nuclear database (e.g., pandemonium effect), fission yield, single beta decay spectrum, etc. \uf0d8We discuss the effects of the single beta decay spectrum by using a fully numerical calculation of lepton wave functions, compared to previous ones using the famous Fermi function. Fang, et al., arXiv: 2001.01689 \uf0d8ENDF VIII.0, for fission yield data, and ENSDF for the decay data. \uf0d82% and 4% deviations for the neutrino and electron spectra. \uf0d8Beta decay is a model-independent way to probe the absolute neutrino masses. \uf0d8KATRIN published its first data in 2019, with a limit on the effective neutrino mass as m\u03bd< 1.1 eV (95% C.L.). \uf0d8We test the reactor rate anomaly using the beta decay data at KATRIN by assuming the 3+1 active-sterile mixing. \uf0d8KATRIN improves the exclusion of the large-\u0394m2 41 solution of the Huber-Muller reactor rate anomaly. \uf0d8RSR: the reactor spectra ratio data test a large part of the small-\u0394m2 41 region. \uf0d8Tritium: KATRIN + Mainz + Troitsk \uf0d8RSR and Tritium limits are complementary, and rule out most of the parameter space. Giunti et al., JHEP 05 (2020) 061 \uf0d8Conversion model for the reactor neutrino flux: using dozens of virtual beta decay branches to fit the aggregate electron spectra of 235U, 239Pu, and 241Pu at ILL. \uf0d8We propose a new realization of the conversion calculation by including the contribution of forbidden decay branches. Using data of ILL U235 beta spectrum Li, et. al., Phys. Rev. D 100 (2019), 053005 7. Reference [1] G. Mention et al., Phys. Rev. D 83 (2011) 073006. [2] T.A. Mueller et al., Phys. Rev. C 832011) 054615. [3] P. Huber, Phys. Rev. C 84 (2011) 024617. [4] KATRIN, Phys. Rev. Lett. 123 (2019) 221802. [5] C. Giunti et al., Phys. Rev. D 99 (2019) 073005. [6] Y.F. Li, D. Zhang, Phys. Rev. D 100 (2019) 053005. [7] D.L. Fang et al., arXiv: 2001.01689. [8] C. Giunti et al., JHEP 05 (2020) 061.", "label": "poster"}
{"text": "LATEX TikZposter ANALYTICAL HALO MODEL OF GALACTIC CONFORMITY Isha Pahwa and Aseem Paranjape Inter-University Centre for Astronomy and Astrophysics, Pune University Campus-Ganeshkhind, Pune - 411007 ipahwa@iucaa.in ANALYTICAL HALO MODEL OF GALACTIC CONFORMITY Isha Pahwa and Aseem Paranjape Inter-University Centre for Astronomy and Astrophysics, Pune University Campus-Ganeshkhind, Pune - 411007 ipahwa@iucaa.in Galactic Conformity is the observation that satellite galaxies in groups whose central galaxy is quenched (or red) are preferentially quenched, even when the groups are restricted to reside in dark matter halos of the same mass. We develop a model to include the effects of \u2018Galactic conformity\u2019 within halo occupation distribution (HOD) framework. This effect has been modelled via the correlation of galaxy colors in a group with the concentration of the common parent dark matter halo. Standard HOD Framework \u2022 fcen(> L|m) - The fraction of m-halos (i.e., halos with masses in the range (m, m + dm)) that have a central galaxy brighter than the luminosity threshold L. \u2022 Nsat(> L|m) - The number of satellites brighter than L in each m-halo with a central brighter than L (assumed to be Poisson distributed with mean). fcen(> L|m) = 1 2 \u0014 1 + erf \u0012log(m/Mmin) \u03c3log m \u0013\u0015 , Nsat(> L|m) = \u0012m \u2212M0 M1 \u0013\u03b1 , [Zehavi et al 2011] with {Mmin, \u03c3log m, \u03b1, M1, M0} being functions of the threshold L. We de\ufb01ne the following quantities that are \ufb01xed by the HOD: Nsat(> L|m) \u2261fcen(> L|m)\u00afNsat(> L|m) ; fcen(L|m) \u2261\u2212\u2202fcen(> L|m)/\u2202L , Nsat(Lm) \u2261\u2212\u2202Nsat(> L|m)/\u2202L ; \u00afNsat(L|m) \u2261Nsat(L|m)/fcen(> L|m) . Color-selcted HOD \u2022Given p(red|Mr) = 0.423 \u22120.175 (Mr + 19.5) and [Paranjape et al 2015] p(red|sat, Mr) = 1.0 \u22120.33 \u0002 1 + tanh \u0000Mr+20.25 2.1 \u0001\u0003 , one can calculate p(red|cen) from equation p(red|L) = p(red|cen, L) \u00afp(cen|L) + p(red|sat, L) \u00afp(sat|L) , where \u00afp(sat|L) = R dm n(m) Nsat(L|m) R dm n(m) [fcen(L|m) + Nsat(L|m)] \u2022 The HOD split by galaxy colour - frcen(L|m) \u2261p(red|cen, L)fcen(L|m) , Nrsat(L|m) \u2261p(red|sat, L)Nsat(L|m) , \u00afNrsat(L|m) \u2261Nrsat(L|m)/fcen(> L|m) = p(red|sat, L)\u00afNsat(L|m) . frcen(L|m)dL is the differential fraction of m-halos with red L-centrals and \u00afNrsat(L|m)dL is the mean differential number of red L-satellites in m-halos with centrals (of any colour) brighter than L. Red fractions as a function of luminosity \u221222.0 \u221221.5 \u221221.0 \u221220.5 \u221220.0 \u221219.5 \u221219.0 Mr 0.0 0.2 0.4 0.6 0.8 1.0 red fraction satellites all centrals psat HOD with galactic conformity \u2022 We introduce conformity between the central and satellite colors in a group using the model of Paranjape et al 2015 which correlates the red fraction of a given galaxy type with the parent halo concentration, i.e., a concentration-dependence of the red fraction of satel- lites/centrals at \ufb01xed luminosity and halo mass by making galaxies in high (low) concentration halos preferentially red (blue). \u2022 Given the fact that distribution of halo concentration c at \ufb01xed halo mass is approximately Lognormal with mean \u00afc(m) \u2261e\u27e8ln c|m \u27e9and logarithmic scatter \u03c3ln c, we de\ufb01ne s \u2261ln(c/\u00afc)/\u03c3ln c . The distribution of s is approximately a standard Gaussian (zero mean and unit variance), independent of halo mass. The conditional red fraction now depends on the parent halo concentration and is given as p(red|sat/cen, s) = (1 \u2212\u03c1) p(red|sat/cen) + \u03c1 \u0398(s \u2212sr,sat/cen) , where sr,sat/cen gives the dividing line between high and low concentrations in each case as sr,sat/cen = \u221a 2 erfc\u22121 [2 p(red|sat/cen)] . \u2022 \u201cgroup quenching ef\ufb01ciency\", \u03c1 \u2208[0, 1]. \u2022 The color selected HOD with conformity - frcen(L|m, s) \u2261p(red|cen, s)fcen(L|m) , Nrsat(L|m, s) \u2261p(red|sat, s)Nsat(L|m) and \u00afNrsat(L|m, s) \u2261Nrsat(L|m, s)/fcen(> L|m) = p(red|sat, s)\u00afNsat(L|m) . 1-halo conformity \u2022 Difference in the red fractions of satellites with red and blue centrals of similar halo mass represented by red and blue colors. \u221222.0 \u221221.5 \u221221.0 \u221220.5 \u221220.0 \u221219.5 \u221219.0 Mr 0.0 0.2 0.4 0.6 0.8 1.0 satellite red fraction \u00bd =0:01 \u00bd =0:65 \u00bd =0:90 Correlation funct", "label": "poster"}
{"text": "A Key Actor in EMI METU English Proficiency Exam: Design, Implementation & Validation Aim The School of Foreign Languages (SFL) initiated a Program Evaluation and Renewal study to investigate the effectiveness of the English Language education curricula at its two departments based on a large scale needs analysis of all relevant stakeholders which involved the evaluation and validation of METU English Proficiency Exam, integral to EMI at METU. Design This research was designed as a mixed methods study. Our approach towards the qualitative / quantitative dilemma was pragmatic. Pragmatism views these two methods as compatible (Howe, 1988, in Teddlie & Tashakkori, 2009), and therefore finds it productive to combine these methods to study phenomena especially in social sciences. Hence, the pragmatic paradigm was the framework of this study. Needs Analysis Data Analysis English Proficiency Examination EPE Revisited- OPERATIONS Design Identifying Target Language Use tasks, task characteristics, theoretical constructs Operationalization Developing test task specifications & test blueprint Administration Alpha & Beta testing Piloting Field-testing Final revision First official version of new EPE Results: Communicative Needs of EMI students Benchmarking, Piloting & External Validity To validate EPE, an experimental pretest-posttest design (N=211) was used to compare EPE scores with an international standardized test, TOEFL IBT, a gatekeeper in many EMI universities. There was a significant positive correlation between EPE and the pretest (r = 0,89, n = 102, p = 0.070); between the two versions of the TOEFL IBT (r = 0,89, n = 102, p = 0.00); and between EPE and the posttest (r = 0.85, n = 115, p = 0.044). EPE cut scores were based on this study. Listening: Field, 2012 Reading: Urqhart & Weir, !998; Khalifa & Weir, 2009 Writing: Shaw & Weir, 2008 Reliability & Internal Validity Predictive Validity & Stakeholder Perception Stakeholders Qualitative / Quantitative Instr. 2612 DBE Ss Surveys / Focus- group interviews 2205 MLD Ss Surveys / Focus- group interviews 133 SFL Instructors Surveys / Interviews 66 Faculty Members Interviews 40 Graduates in 19 Firms Interviews 14 Employers in 12 Firms Interviews Document Analysis of student essays, exams, lab reports from all faculties Communicative Activity Required Skill Listening -listening in-class -assigned listening Very deep attention understanding instructions Medium to deep attention following lectures /discussions Reading -background reading -intensive reading search reading reading longer texts careful reading understanding instructions analytical/critical reading interpreting visuals Writing -writing in -class -assigned writing note-taking writing responses to exam projects, reports, papers fluency & coherence Speaking -spontaneous speech -planned speech communicating with instructors asking & answering Q\u2019s delivering presentations fluency in speech Grammar & Vocabulary basic structures - wide range academic lexis \u2022 For quantitative data, descriptive and inferential statistics were employed. Depending on the results of tests of normality, either ANOVA/ t-Test or Kruskall- Wallis and Mann-Whitney U tests were used. \u2022 As for qualitative data, the recordings of interviews were analyzed by MaxQDA 11. Miles and Hubermann Qualitative Data Analysis Framework was used (1994). Theoretical Framework of Test Design Sociocognitive Framework, Weir, 2005 The relationship between, TOEFL Pre-and Po EPEsttests Reliability: Cronbach\u2019s alpha, which measures the internal consistency of a group of items was found to be (\u03b1= .81). This alpha coefficient is high (\u226570 ) in terms of testing. Item Discrimination: The Rpbi mean for the MC items was found to be Rpbi .33, meaning that the exam discriminated well between higher and lower proficiency levels. Items with Rpbi in the .30 - .49 range are considered strong discriminators. Item difficulty: P values for the scored items show a desired distribution of the P (.4 ", "label": "poster"}
{"text": "Figura 1. Intervalos para la Varianza aditiva estimada, para los grupos de a\u00f1os. Figura 2. Intervalos para la Heredabilidad estimada, para los grupos de a\u00f1os. 0.0021 0.0060 0.0054 0.0113 0.0000 0.0050 0.0100 0.0150 0 1 2 3 Grupos Va Ln 0.09 0.25 0.16 0.31 0.00 0.10 0.20 0.30 0.40 0 1 2 3 Grupos Heredabilidad Ln Figura 3. Intervalos para la Varianza aditiva estimada, para los grupos de a\u00f1os. Datos en Ln. Figura 4. Intervalos para la Heredabilidad estimada, para los grupos de a\u00f1os. Datos en Ln. Cva Cva Ln Grupo 1 0.055 0.023 Grupo 2 0.080 0.036 Cuadro 1. Coeficientes de variaci\u00f3n aditivos para cada uno de los grupos de a\u00f1os, con datos originales y en LN. Evoluci\u00f3n de la Variabilidad Gen\u00e9tica para peso a edad comercial en una poblaci\u00f3n seleccionada de camar\u00f3n blanco del Pac\u00edfico [Penaeus (Litopenaeus) vannamei]. Cala N\u00b9*, Montaldo HH\u00b9, Castillo-Ju\u00e1rez H\u00b2, Campos-Montes GR\u00b2, Ruiz-L\u00f3pez FJ\u00b3. Universidad Nacional Aut\u00f3noma de M\u00e9xico\u00b9, Universidad Aut\u00f3noma Metropolitana- Xochimilco\u00b2, Centro Nacional de Investigaci\u00f3n en Fisiolog\u00eda y Mejoramiento Animal, INIFAP\u00b3. necamo4@comunidad.unam.mx Introducci\u00f3n En una poblaci\u00f3n de tama\u00f1o efectivo limitado bajo selecci\u00f3n, se pueden producir cambios en las varianzas gen\u00e9ticas y ambientales a trav\u00e9s de las generaciones, que pueden reflejarse en cambios en la variabilidad gen\u00e9tica. Estos cambios manifiestan una disminuci\u00f3n en la variaci\u00f3n gen\u00e9tica a trav\u00e9s de las generaciones para la poblaci\u00f3n en selecci\u00f3n. Objetivo Estimar cambios los componentes de variabilidad gen\u00e9tica y ambiental para P130 en 8 generaciones de una poblaci\u00f3n n\u00facleo de camar\u00f3n blanco del Pac\u00edfico bajo selecci\u00f3n. Material y M\u00e9todos Se usaron datos de ocho generaciones (2003-2010) de una poblaci\u00f3n Mexicana de camar\u00f3n blanco del Pacifico seleccionada para peso a los 130 d\u00edas, con su respectivo pedigr\u00ed. Se analizaron 123,561 registros, procedentes de la progenie de 1043 madres y 746 padres. La estructura es por familias, provenientes de apareamientos de un macho con dos hembras mediante inseminaci\u00f3n artificial. Se utiliz\u00f3 un modelo lineal mixto en ASReml. Los efectos fijos fueron a\u00f1o-estanque-sexo y los efectos lineal y cuadr\u00e1tico de la edad a la cosecha como covariables. Los efectos aleatorios, el efecto gen\u00e9tico aditivo, el efecto de ambiente com\u00fan de familia de hermanos y el error. En el modelo se consideraron varianzas heterog\u00e9neas por generaci\u00f3n (a\u00f1o). Resultados y Discusi\u00f3n Los par\u00e1metros usados para evaluar los cambios fueron la heredabilidad \u201c ( )\u201d, la varianza aditiva \u201c \u201d y el coeficiente de variaci\u00f3n aditivo \u201c (\u221a \u0302)\u201d. Se estimaron las tendencias con las ecuaciones de regresi\u00f3n lineal y polinomiales de segundo y tercer orden para , y . Los resultados para la regresi\u00f3n lineal muestran una tendencia negativa P < 0.05, sin embargo el coeficiente de variaci\u00f3n se\u00f1ala una tendencia positiva P < 0.05, lo que es contradictorio. Tambi\u00e9n se realizaron an\u00e1lisis similares usando el logaritmo natural de P130. Posteriormente se dividi\u00f3 la base en dos grupos de a\u00f1os, uno del 2003 al 2006 y otro del 2007 al 2010, intentando buscar una tendencia en los estimados, se analiz\u00f3 la , y graficando los intervalos para , (Figuras 1, 2), de igual forma se analizaron los datos transformados a logaritmo natural (Figuras 3, 4). Los coeficientes de variaci\u00f3n calculados para cada grupo se presentan en el cuadro 1. Conclusi\u00f3n Los resultados obtenidos de los an\u00e1lisis para y usando los datos originales y transformados a logaritmo natural de P130 no indican cambios significativos a trav\u00e9s del tiempo para ninguno de los dos par\u00e1metros, lo que coincide con los resultados de y sugiere que hay efectos importantes de escala que deben tomarse en cuenta para analizar este tipo de datos , por lo cual no podemos afirmar estad\u00edsticamente que para los datos utilizados en \u00e9ste estudio haya habido una p\u00e9rdida significativa de la variabilidad gen\u00e9tica aditiva en respuesta al proceso de selecci\u00f3n en el transcurso de los a\u00f1os posteriores al 2005. Todav\u00eda otra posibilidad es qu", "label": "poster"}
{"text": "Data from OSM has been automatically categorised in several accessibility classes, in accordance with the national and regional legislation. Two different types of maps have been produced: current status, with footways, crossings, kerbs and obstacles represented, and project status, with modi\ufb01ed elements included in the plan. 1000 kerbs mapped 400 crossings mapped 31% inaccessible kerbs 10000 images uploaded in Mapillary 60000 \u20ac/km costs estimated 155 buildings assessed 12 recurring situations 37 standard intervention typologies 10 meetings were organised in 10 different locations, corresponding to the 10 sub-departments of the city. The aim was to present the project and collaboratively decide the areas/paths to be mapped and where to assess accessibility during the following mappings events. 10 mapping events were organised with citizens and local organizations both as demonstration and training for the use of mapping tools (FieldPapers, Mapillary, OSMAnd), and for collection of local expertise on accessibility. Then expert mappers \ufb01nalized the collection in information and the upload on OpenStreetMap. Various open tools have been used: FieldPapers during mapping events; OsmAnd during technical mapping; Mapillary for collection of street-level pictures; JOSM for editing OpenStreetMap data; QGIS for the production of \ufb01nal cartographic maps of the of\ufb01cial plan. PARTICIPATORY MEETINGS MAPPING The \"PEBA - Piano per l'Eliminazione delle Barriere architettoniche\" (Plan for the elimination of architectural barriers) is a legislative tool aiming at ensuring full accessibility of urban paths, spaces and buildings for all the people. The local administration of Padua \ufb01nanced the creation of the PEBA of the city, with the brand \"Padova + Accessibile\" (Padua more accessible). More information at http://www.comune.padova.it/ peba. The two main criteria for the development of the plan have been a wide participatory vision and the use of open geospatial tools for analysis. OpenStreetMap has been selected as the core tool for mapping accessibility. elements. 10 meetings with citizens and associations 66 invited associations 40 km of footways/paths mapped 137 disabled designated parking spaces 370 geolocated +reports 229 obstacles observed 1.5 km of non-accessible sidewalks 17 km of sidewalks with limited accessibility OUTPUT MAPS CREDITS The local administration of Padua (Comune di Padova) funded the realization of the PEBA, including participatory meetings and mapping events and activities (contact person arch. Alberto Marescotti). Wikimedia Italia provided free patronage for mapping events; various Wikimedia Italia volunteers contributed to the mapping and editing activities. Image \u201cPadova+accessibile\u201d by arch. Alberto Marescotti. Font OpenDyslexic \u00ae. Background image \u00a9OpenStreetMap contributors. Project manager Elena De Toni. The PEBA (Plan for the elimination of architectural barriers) of the city of Padua has been the \ufb01rst example in Italy of the direct use of OpenStreetMap as main tool to collect information and derive decisions for the characterization of accessibility of public areas and paths. In the area of Padua, data in OSM have been improved in relation to information on accessibility of public areas and path, especially for disabled people; in addition to this, through the involvement of citizens and local organizations, the use of open source technology and the revision and application of a tagging scheme for OpenStreetMap, accessibility information will be easily updated and extended in the future. CONCLUSIONS TAGGING SCHEME PEBA IN NUMBERS PEBA During the activities of the PEBA, a short guide on how to map parkings for people with disabilities was produced and then shared and promoted to a few associations working on disabilities. In 4 months the number of these parking spaces increased from 0 to ~140, allowing the production of a dynamic map that is being continuosly updated. PARKING SPACES This work is available at http:/", "label": "poster"}
{"text": "Are Physicians Ready to Take up Leadership Roles in Planetary Health? Suraj Bhattarai1,2; Omary Chillo3; Biljana Gjoneska4; Dipendra Khatiwada5; Jaifred Christian F. Lopez6; Atiya Mosam7; Juan Carlos N\u00fa\u00f1ez Enr\u00edquez8; Duha Shellah9; Nora Grasselli10 1Global Health Research & Medical Interventions for Development, Nepal; 2London School of Hygiene & Tropical Medicine, UK; 3Muhimbili University of Health and Allied Sciences, Tanzania; 4Macedonian Academy of Sciences and Arts, North Macedonia; 5College of Medical Sciences, Nepal; 6Duke University, USA; 7Mayibuye Health and University of the Witwatersrand, South Africa; 8UMAE Hospital de Pediatr\u00eda CMN Siglo XXI, IMSS, Mexico; 9Palestine Academy for Science & Technology, Palestine; 10European School of Management and Technology, Germany. INTRODUCTION \u2022 Physicians\u2019 role is primarily thought to provide patient care. \u2022 They also contribute to improve healthcare systems & health indicators.a \u2022 However, their role in planetary health has not been established nor defined yet. \u2022 Young Physician Leaders Programme (YPL) is a flagship training programme of the InterAcademy Partnership (IAP) \u2013 the parent academy of 149 national science academies worldwide.b \u2022 IAP has a mission to \u201cfoster the next generation of research and science policy leaders\u201d by strengthening critical capacities for leadership.b REFERENCES aInstitute of Medicine (US) Division of Health Sciences Policy. Medical Education and Societal Needs: A Planning Report for the Health Professions. National Academies Press (US); 1983. Chapter 4, The Physicians\u2019 Role in a Changing Health Care System. bThe InterAcademy Partnership. www.interacademies.org cMyers SS, Potter T, Wagner J and Xie M. Clinicians for Planetary Health. One Earth; 2022. dMoser AM, Stigler FL and Haditsch B. Physicians\u2019 responsibility for planetary health. The Lancet Planetary Health; 2017. METHODS \u2022 A semi-structured questionnaire was developed based on literature review and distributed electronically to the 10-year YPL cohorts (2011- 2022), with assistance from the IAP Secretariat. \u2022 The 8-member YPL Alumni Steering Committee coordinated the study, in collaboration with the ESMT. \u2022 EMST ethics committee provided ethical clearance to the survey. \u2022 Descriptive statistics was used to analyse the data. RESULTS \u2022 Out of 235 physicians approached, 77 (33%) completed the survey. \u2022 51% were female. Majority (73%) represented LMICs. \u2022 52% of the respondents were engaged in clinical practice, 60% in research, 29% in strategic and policymaking roles, 14% in bureaucracy. CONCLUSIONS \u2022 Physicians are extending their work area beyond curative medicine, embracing upstream approaches to impact population health. \u2022 Therefore, it is important to acknowledge physicians as key stakeholders of planetary health and engage them in global initiatives. OBJECTIVE To explore the engagement of YPL alumni in health sector in the context of emerging global discourse on planetary health. Young Physician Leaders (YPL) at a glance \u2022 YPL programme is running since 2011. \u2022 It has 21 new members and 231 Alumni across 5 continents. \u2022 Each year, national academies send their nominations to IAP and its expert medical panel selects the new cohort (~20 members). \u2022 World Health Summit, M8 Alliance and European School of Management and Technology (ESMT) are main programme partners, among others. \u2022 While 30% of the respondents worked from central or federal level, the majority (58%) worked from local level (district or community facilities). DISCUSSION \u2022 Physicians\u2019 community represent highly educated and respected professionals and apt science communicators, so they could be the most suitable messengers/ debaters/ negotiators for planetary health.c \u2022 Next generation physicians should be educated to recognize planetary health as the foundation for any efforts to improve human health.d May 27-29, 2024 Geneva, Switzerland Contact: Dr. Suraj BHATTARAI Director and Investigator GLOHMED, Nepal E: surajbhattarai.m", "label": "poster"}
{"text": "X-ARAPUCA as photon detection system of SBND Ana Machado for SBND Collaboration NEUTRINO 2024 June 16-22, 2024 \u2013 Milan, Italy Three LArTPC detector to study short range neutrino oscillation \u2022 Neutrino-argon interactions at GeV energy scale. Millions of n\u00b5 and thousands of ne from two neutrino beams \u2022 Verify the \u201clow-energy excess\u201d anomaly Investigate the excess of ne observed by MiniBooNE experiments \u2022 Search for sterile neutrino Discover or exclusion of 1 eV-scale sterile neutrino mass region \u2022 Beyond Standard Model Physics 192 X-ARAPUCA 176 ARARA readout SensL - 3x3m2 SiPM. (C-series 30050-A1) 88 VUV OPTO 400nm PTP coating EJ286 88 Visible OPTO 450nm EJ280 16 APSAIA readout Hamamatsu - 6x6m2 SiPM. (S13360-6050 VE & HS) 8 VUV OPTO 400nm PTP coating Glass to Power 8 Visible OPTO 450nm Glass to Power FILTER (400nm cutoff) PTP (emission 350nm) SiPM WLS plate LAr scintillation light FILTER (450nm cutoff) SiPM WLS plate Visible light Photon Detection System Active elements: on the PD-BOX, behind the anode. \u2022 120 8\u201d Hamamatsu Cryogenic PMT\u2019s (96 TPB coated + 24 uncoated) \u2022 192 X-ARAPUCA (96 VIS + 96 VUV) Passive element: at the cathode. Wavelength-Shifting Reflective plates (TPB coated) 64 double-sided Short Baseline Near Detector TPC Cathode Plane at -100 kV divides the detector into 2 drift volumes. Drift distance is 2 m, drift time is 1.28ms Anode Plane on either side. Each consists of 3 planes of wires with 3 mm spacing and different angle per plane. Total of 11,260 wires Cold (89K) Electronics to pre-amplify and digitize signals Field Cage that wraps around the 2 LArTPCs to step down the voltage & ensure uniform electric field of 500 V/cm. Cosmic Ray Tagger (CRT) Scintillator strips with SiPM readout 142x32 channels X-TDB X-ASB All PCB boards were tested in cryogenic temperature 60 SiPMs was tested - 48 6050-VE (VBr = +53V @RT) - 12 6050-HS (VBr = +38V @RT) A total of 777 X-TDBs were tested at the LN2 temperatures and able to see light. 704 were required. Only 1 \u201cbad\u201d board was identified Digitized signal from the HS test \u2013 APSAIA \u2013 ARAPUCA POWER SUPPLY AND INPUT AMPLIFIER \u2013 ARARA \u2013 ARAPUCA ANALOG READOUT AMPLIFIER Readout Electronics The APSAIA will power the SiPMs and amplify their 32 output signals. It is hosted in the outer flange of SBND. Each board has 8 channels with input connectors. The power supplies are designed to meet the SiPMs' requirements, and the amplifiers process the SiPMs' output signals. Each channel has an MCX output connector. The power supply and serial port connector use a standard DB15 connector. The supply voltage for the SiPMs is remotely adjustable up to 60 V with a resolution of less than 100mV. The power supplies and amplifiers are controlled by a microcontroller connected to an RS232C port. RJ45 \u00e0 DB37, cold side view The preamplifier board conditions and biases the signal between the X-ARAPUCA light collection hardware and the signal capture hardware The bias voltage must be programmed remotely using an RS232c. The power supply is available via a cable with a DSUB9 connector. The 352 signals for flange are inputs for ARARA board. Into the ARARA board the signals are ganged by 4. RAVANA board convert signals from the ARARA to the CAEN 1740 digitizers Single-channel prototype of the pre-amplifier by AGE scientific These preamp modules are: - Double width 6U VME cards in custom crate. - Powered by externally provided 8V DC - 64 input channels for 16 output channels - Compliant with FNAL Electrical Design Standards for Electronics The amplifier characteristics are as follows: - Minimum gain of 20, adjustable via microcontroller if other gain values are needed. - Sufficient bandwidth for processing 30 ns rise-time signals, DC-coupled. - Output impedance of 50 \u03a9. ASSEMBLY & INSTALLATION 1o step: The assembly of the mechanical and optical parts (dichroic filters and light guide) was done at Unicamp 2 o step : The PCB board installation in each X- ARAPUCA was carried out at Fermilab. Finally, 4 VUV X-A", "label": "poster"}
{"text": "Comparison of fatty acid composition in grass-fed and grain-fed horse meat Aidyn Igenbayev, Shyngys Amirkhanov, Muhtarbek Kakimov, Alida Kanabekova S. Seifullin Kazakh Agrotechnical University, Astana, Kazakhstan Reference: Igenbayev, A., Amirkhanov, S., Ospankulova, G., Kardenov, S., Baytukenova, S., & Ali Shariati, M. (2022). Determination of the fatty acid composition and fatty acids trans-isomers in the horse, stall horse, mutton, beef and pork meat. Potravinarstvo Slovak Journal of Food Sciences, 16, 800\u2013809. https://doi.org/10.5219/1799 The objective of this research was to analyze the fatty acid composition of horse meat. The study involved the selection of two distinct groups of horses: 1) horses that were raised and fed in a pasture; 2) horses that were kept in stalls. For the analysis, pasture horse meat (Kazakh horse breed), and stall horse meat (Kazakh horse breed) were purchased from meat markets and supermarkets in Astana, Kazakhstan. Samples were obtained from four di\ufb00erent carcass muscles (back muscles, thigh muscles, rib muscles, neck muscles) of each animal, an average of 500 grams of sample. The samples obtained were stored at a temperature of - 18 \u00baC. Horse meat for pasture and stall keeping was supplied from farms engaged in horse breeding in an appropriate way of feeding. This analysis compares the fatty acid composition of grass-fed and grain-fed horse meat, speci\ufb01cally in the loin cut. The data shows that grain-fed horse meat has a higher percentage of saturated fatty acids (SFA) compared to grass-fed horse meat, with the content being 40.32% and 37.43% respectively. Conversely, grass-fed horse meat has a higher percentage of monounsaturated fatty acids (MUFA) compared to grain-fed horse meat, with the content being 48.12% and 40.36% r e s p e c t i v e l y. T h e p e r c e n t a g e o f polyunsaturated fatty acids (PUFA) is also higher in grain-fed horse meat compared to grass-fed horse meat, with the content being 19.31% and 14.44% respectively. Table 1. Fatty acid content in muscle lipid fraction of grass fed horse meat, % of total fatty acids Table 2. The fatty acid content in the muscle lipid fraction of grain-fed horse meat, % of total fatty acids This study reports the levels of trans fatty acids (TFAs) in di\ufb00erent cuts of grass-fed horsemeat, revealing that the TFA content varies across cuts with the highest level in loin (1.85%) and the lowest in round (1.66%). The levels of TFAs in rib (1.68%) and neck (1.70%) are similar to each other and fall in between the levels observed in loin and round. This study presents data on the levels of trans fatty acids (TFAs) in various cuts of grain-fed horsemeat, revealing that the TFA content is markedly higher in round (5.54%) and neck (5.52%) than in loin (2.75%) and rib (3.56%). These \ufb01ndings suggest that the TFA content in horsemeat can be in\ufb02uenced by the type of feed given to the animals. As high intake of TFAs has been linked to increased risk of cardiovascular disease, these results provide important information for assessing the potential health risks associated with the consumption of grain-fed horsemeat. This comparison suggests that the type of diet fed to horses can have a signi\ufb01cant impact on the fatty acid composition of their meat. The higher content of SFAs in grain-fed horse meat may increase the risk of cardiovascular disease, while the higher content of MUFAs in grass-fed horse meat may have potential health bene\ufb01ts. The higher content of PUFAs in grain-fed horse meat may also be bene\ufb01cial, as PUFAs are essential fatty acids that have been linked to a reduced risk of cardiovascular disease. However, the speci\ufb01c types of PUFAs present in grain-fed horse meat should be taken into consideration, as some types of PUFAs may be more bene\ufb01cial than others. Further studies are needed to explore the health implications of consuming grass-fed vs. grain- This research is funded by the Ministry of Agriculture of the Republic of Kazakhstan (BR1076499", "label": "poster"}
{"text": "Analysis \u5927\u8cea\u91cf\u661f Telescope Resolution Reference !\"CO(2 \u22121) ALMA 1.12\u201d (53 pc) Leroy et al. (2021) H\u03b1 VLT 0.92\u201d (44 pc) Emsellem et al. (2022) Giant molecular clouds and their Type classification in M74 Fumika Demachi 1, Yasuo Fukui 1, Kengo Tachihara 1, Rin Yamada 1, Kazuki Tokuda 2,3, Shinji Fujita 4, Masato Kobayashi 5 Kazuyuki Muraoka 6, Ayu Konishi 6, Tsuge Kisetsu 4, Toshikazu Onishi 6, Akiko Kawamura 3 (Nagoya university 1, Kyushu university 2, National Astronomical Observatory of Japan 3, University of Tokyo 4, University of Cologne5, Osaka Metropolitan university 6 ) 1. 3. Need to expand samples to establish a general picture of GMC evolution. [ The goal of this study ] Establish the method of Type classification based on \ud835\udc3f!\" Suitable for resolving GMCs without contamination in a line of sight Distance: 9.7 Mpc (Anand et al. 2021) Inclination: 8.9\u00b0 (Lang et al. 2020) \ud835\udc40()*+ = 10,-./0\ud835\udc40\u2299, \ud835\udc4023 = 104.5-\ud835\udc40\u2299 (Leroy et al. 2021) M74 Giant molecular clouds (GMCs) are the main star formation sites and their evolutions are important to understand galaxy evolution. In this poster, we discuss GMC evolution in nearby spiral galaxy M74 by using spatially resolved GMC samples. We classified GMCs into 3 types based on H\u03b1 luminosity (\ud835\udc3f67) of HII regions with GMCs, and Type I (without star formation) are 58, Type II (with \ud835\udc3f67 < 10/5.8 erg s9,) are 202, and Type III (\ud835\udc3f67 > 10/5.8 erg s9,) are 172, then obtained these results, (1) the young star clusters clearly associated with Type II and III GMCs, and \ud835\udc3f67 and cluster mass show tight correlation for Type III (2) massive Type I GMCs show the sign of embedded star formation and Type II GMCs are affected by extinction more than Type III, and (3) Type III are the most virialized state. For these results, we interpreted GMC Type classification as GMC evolutionary sequence from Type I to III with active star formation. In this study, Type classification are applied in grand design spiral galaxy out of the local group for the first time. 1. Identify GMC by PYCPROPS*1 and HII region by Astrodendro*2. 2. Determine the association between GMC and HII region if their boundaries are overlapped, and classify GMCs based on \ud835\udc3f2:. 3. Compare Type GMCs with clusters*3 obtained by HST and 21 \u00b5m emissions*4 obtained by JWST to check consistency with results of LMC and the effects of H\u03b1 extinction, respectively. \u2192 Classify GMCs based on H\u03b1 luminosity (\ud835\udc3f67) 10/5.8 erg s9, of associated HII regions because H\u03b1 is more uniformly surveyed Results 4. We identified 58 Type I, 202 Type II, 172 Type III (Fig.1). The median of GMC mass and radius increase Type I 10#$.&) HII region *1: Rosolowsky et al. 2021, *2: Rosolowsky et al. 2008, *3: Adamo et al. 2017, *4: Lee et al. 2023 Fig.3) Histogram of separation between nearest GMCs and clusters. The orange line indicates typical GMC-GMC separation. Fig.4) Scatter plot between total cluster mass and H\u03b1 luminosity associated common GMCs. The size of marker indicate the number of clusters with each GMC. The cluster mass increase with \ud835\udc3f2: especially for Type III (Fig. 4). 35% of Type I and more than 80% of Type II and III are associated with 21 \u00b5m emission. Correct H\u03b1 extinct lu", "label": "poster"}
{"text": "Ergebnisse \u2022 Diskriminanzf\u00e4higkeit zw. Bildern \u03b72T1 = .28, \u03b72T2 = .33 \u2022 Inter-Rater-Reliabilit\u00e4t ICCT1 = .81, ICCT2 = .84 \u2022 Test-Retest-Reliabilit\u00e4t r = .93 \u2022 Hauptkomponentenanalyse 8-Faktorenl\u00f6sung \u2022 Tucker-Korrelationskoeffizient rT1 = |0.82|, rT2 |1.00| Empirische Bildanalyse Validierung von RizbA an bildnerischen Arbeiten erwachsener Lai*innen Schoch K.1,2 & Ostermann T.1 1 Universit\u00e4t Witten/Herdecke, Fakult\u00e4t f\u00fcr Gesundheit, Department Psychologie und Psychotherapie 2 Hochschule f\u00fcr K\u00fcnste im Sozialen, Ottersberg, Institut f\u00fcr Kunsttherapie und Forschung Hintergrund Literatur Epstein, C. (2019, 22. M\u00e4rz). Bildlicher Ausdruck von Depression: Erprobung des Ratinginstruments RizbA an Bildstichproben aus dem klinischen Kunsttherapiesetting. Zenodo. https://doi.org/10.5281/zenodo.3365921 Jan\u00dfen, B. (2018, 31. August). Erprobung des Ratinginstruments f\u00fcr zweidimensionale bildnerische Arbeiten (RizbA): Ansatz zu einer m\u00f6glichen Untersuchung des bildnerischen Ausdrucks von Schmerz in gemalten Bildern von Menschen mit chronischer Schmerzsymptomatik. Zenodo. https://doi.org/10.5281/zenodo.3407808 Schoch, K., & Ostermann T. (under review). Psychometrics of art: Validation of RizbA, a quantitative rating instrument for pictorial expression. Psychology of Aesthetics, Creativity and the Arts. Schoch, K. (2018). Ratinginstrument f\u00fcr zweidimensionale bildnerische Arbeiten (RizbA): Fragebogen in deutscher Sprache. Zenodo. DOI:10.5281/zenodo.2530858 Schoch, K. (2018). Jenseits von gut und sch\u00f6n: Entwicklung eines quantitativen Ratinginstruments f\u00fcr zweidimensionale bildnerische Arbeiten (RizbA). Musik-, Tanz- und Kunsttherapie: Zeitschrift f\u00fcr K\u00fcnstlerische Therapien im Bildungs-, Sozial- und Gesundheitswesen. 28(2), 131-138. https://doi.org/10.5281/zenodo.1479716 Schoch. K., Gruber. H., & Ostermann, T. (2017). Measuring art: Methodical development of a quantitative rating instrument measuring pictorial expression. The Arts in Psychotherapy, 55, 73-79. https://doi.org/10.5281/zenodo.1479694 Diskussion \u2022 Reliabel und generalisierbar auf Bildmaterial von Lai*innen \u2022 Praxisdokumentation, Grundlagen- und Anwendungsforschung Dokumentation und Analyse von Bildern und Prozessen Korrelationen mit anderen Konstrukten Gruppenvergleiche \u2022 Abgeschlossen Dritte Validierungsstudie an Gegenwartskunst \u2022 Durchgef\u00fchrt Pilotstudien zu spezifischen Populationen Chronische Schmerzsymptomatik (Jan\u00dfen, 2018) Rezidivierende Depression (Epstein, 2019) \u2022 In Entwicklung Manual \u2022 In Planung Machine Learning-Ans\u00e4tze kerstin.schoch@hks-\u00adottersberg.de www.kunsthochzwei.com/forschung Tab.1. Antwortformat: Sechsstufige Likert-\u00adSkala trifft \u00fcberhaupt nicht zu trifft nicht zu trifft eher nicht zu trifft eher zu trifft zu trifft voll- kommen zu \u2718 Limitierung Weitere Validierung Faktorenstruktur CFA, SEM Weitere Populationen Bildmaterial und Rater*innen Tab.2. Fragebogen: Items und deren G\u00fctekriterien (T1) Nr. Itembeschreibung pi si2 \ud835\udec82 ICC 1 Das Bild enth\u00e4lt zeichnerische Elemente .58 1.31 .52 .96 2 Das Bild enth\u00e4lt malerische Elemente .61 0.92 .41 .93 3 Die Darstellungsweise ist gegenst\u00e4ndlich .43 1.67 .63 .97 4 Die Darstellungsweise ist abstrakt .61 1.19 .52 .96 5 Der Farbauftrag ist pastos .33 0.63 .31 .90 6 Die vorherrschende Farbgebung ist leuchtend .58 1.08 .52 .96 7 Im Bild befinden sich vorwiegend reine Farben .47 0.52 .28 .88 8 Im Bild befinden sich vorwiegend Mischfarben (Sekund\u00e4rfarben) .50 0.72 .36 .92 9 Im Bild sind Komplement\u00e4rkontraste vorhanden .51 1.34 .51 .96 10 Im Bild enthaltene Formen sind vorwiegend organisch .52 0.65 .34 .92 11 Im Bild enthaltene Formen sind vorwiegend geometrisch .39 0.98 .46 .94 12 Die Linienf\u00fchrung verl\u00e4uft vorwiegend gebogen .55 1.07 .50 .95 13 Die Linienf\u00fchrung verl\u00e4uft vorwiegend eckig .30 0.90 .49 .95 14 Das Bild enth\u00e4lt unbearbeitete Fl\u00e4chen .53 1.72 .51 .96 15 Das Bild wirkt tief .32 0.44 .29 .88 16 Das Bild ist perspektivisch .33 0.62 .34 .91 17 Das Bild ist frei von Perspektive (aperspektivisch) .60 0.71 .31 .90 18 Das Bil", "label": "poster"}
{"text": "El riesgo CV , se define como la probabilidad de un individuo de tener un evento cardiovascular en un per\u00edodo de tiempo determinado (por ejemplo, en los pr\u00f3ximos 5 o 10 a\u00f1os). La ecuaci\u00f3n de riesgo de Framinghan define como un primer evento CV al IAM, angina de pecho, ataque cerebral isqu\u00e9mico, enfermedad vascular perif\u00e9rica, insuficiencia card\u00edaca congestiva o una muerte cardiovascular. El objetivo de hacer una evaluaci\u00f3n del riesgo CV es identificar los factores de riesgo, estimar el riesgo de hacer un evento CV y utilizar este c\u00e1lculo para hacer un manejo terap\u00e9utico apropiado de aquellos factores. El presente estudio se llevo a efecto en los CS. San Lorenzo , Pile , El Aromo , Manantiales , San Mateo , con una poblaci\u00f3n de 32 personas , de las cuales se evidencia que 27/32 presenta un RCV bajo , 2/32 presenta un riesgo MUY ALTO , por ser diab\u00e9ticos , y de riesgo moderado 3/32. Lo que llamo la atenci\u00f3n fue que de los 32 evaluados 22 presentan SOBREPESO y 4 con OBESIDAD , adem\u00e1s que el 100% del grupo es SEDENTARIO . Al momento no se encuentra implementado un programa de salud preventiva en nuestro distrito de salud , cosa alarmante , por eso la pregunta \u00bf Se preocupa la salud por nuestra salud?? Quien se preocupa por que los funcionarios tengan SALUD \u00bf?.Los m\u00faltiples requerimientos no solo en el trabajo cl\u00ednico si no administrativo absorbe de forma casi total el tiempo de los trabajadores , dando lugar al desarrollo de patolog\u00edas que silenciosamente evolucionan tanto en la salud cardiovascular como HTA, DM , DLP , OBESIDAD , Problemas de salud mental como trastornos ansiosos , depresi\u00f3n etc . Es necesario la implementaci\u00f3n de medidas que nos protejan , asegurando bienestar SALUD a los trabajadores del \u00e1rea de la salud , en aras de mejor atenci\u00f3n a nuestros usuarios y al mejoramiento de el sistema de salud del pa\u00eds. RIESGO CARDIOVASCULAR EN EL PERSONAL DEL DISTRITO DE SALUD NUMERO DOS SECTOR RURAL SCORE DE FRAMINGHAN UNIVERSIDAD DE PIURA MAESTRIA EN SALUD OCUPACIONAL \u00bf Hay salud en la salud? Distribuci\u00f3n del Personal de salud del \u00e1rea rural , distrito 2 BAJO 5% MODERADO 5-9% ALTO 10-19% MUY ALTO 20 o > 0 2 4 6 8 10 Serie1 0 5 10 15 20 25 SOBREPESO BIBLIOGRAFIA . 1.Programa de Salud Cardiovascular. Reorientaci\u00f3n de los Programas de Hipertensi\u00f3n y Diabetes. Ministerio de Salud de Chile. 2002 . Prevenci\u00f3n Primaria de Enfermedad Coronaria. Tablas de Framingham para la estimaci\u00f3n de riesgo coronario a 10 a\u00f1os adaptadas a la poblaci\u00f3n chilena. Programa de Investigaci\u00f3n de Factores de Riesgo de Enfermedad Cardiovascular. 2007. Universidad de Talca. http://pifrecv.utalca.cl . Determinaci\u00f3n y Prevalencia de Factores de Riesgo Cardiovascular en el Personal de la Brigada de Caballer\u00eda Blindada No 11 Gal\u00e1pagos, Riobamba ELABORADO POR: DRA SUSANA JASMIN CABRERA MERO MANTA OCTUBRE 2014 RIESGO CARDIOVASCULAR 22 PCTES CON SOBREPESO 4 CON OBESIDAD", "label": "poster"}
{"text": "We wish to thank the Allen Institute founders, Paul G. Allen and Jody Allen, for their vision, encouragement, and support. An integrated imaging and staining platform for cubic millimeter scale array tomography Forrest Collman, Robert Sera\ufb01n, Sarah Davis, Olga Gliko, Tom M Keenan, Kristy Parker, Linnaea E Ostro\ufb00, Stephen J Smith Synapse Biology Department, Allen Institute for Brain Science, Seattle WA 98103 Array tomography (AT) involves reconstruction of images acquired from arrays of serial ultrathin sections, which can be imaged by fluorescence microscopy (FM-AT) for proteometric analysis, or by scanning electron microscopy (EM-AT) for higher resolution. Axial resolution is defined by the thickness of physical sections (50-200 nm); the lateral resolution of FM imaging is optimal given the direct adhesion of sections to an optical coverslip. However, the throughput of data acquisition is slowed by the image acquisition time, and the need for human intervention to stain and set up samples on the microscope. The first AT systems acquired data at a throughput of ~16 seconds per 4 channel image (Micheva 2007). Recent work incorporated a hardware-based autofocus technology that improved throughput to 5-12 sec per 4 channel image (Rah 2013), achieving 0.1 mm3 in 878 imaging hours with 200 nm-thick sections. Data acquisition throughput is further impaired by the overhead involved in staining and setting the sample up for imaging. As part of the Open Synaptome Project (http://opensynapto.me) effort to improve all aspects of ATomo based synaptic analysis, we are developing a next-generation system to achieve imaging throughput on the order of 0.2mm3 per day per microscope. We will describe the design of the imaging system, which include hardware-based autofocus, large format sCMOS sensors, motionless high intensity wide-field laser illumination, and a custom open-source software solution. We will also describe our efforts to construct a robofluidic staining solution fully integrated with the microscope. Our goal is to enable continual staining and imaging without human intervention, thus increasing both throughput and consistency of results ultrathin section onto coverglass IF stain IF imaging poststain FESEM elution ABSTRACT ARRAY TOMOGRAPHY IMAGING brain-map.org alleninstitute.org y (mm) 0 ul 50 ul 100 ul 150 ul 200 ul 250 ul 300ul Fluorescein Intensity (AU) 0 500 100 200 300 400 Wash In x (mm) y (mm) Wash Out 0 ul 50 ul 100 ul 150 ul 200 ul 250 ul 300ul Fluorescein Intensity (AU) 0 500 100 200 300 400 x (mm) 300ul 0 10 x (mm) >95% washin with 200-250ul >99% washout with 300 ul Non-saturating/quenching concentration of fluoroscein 10x air objective, median intensity of field, 50\u03bcl increments Fully automated pipetting and image acquisition across x,y grid Pipette In Pipette Out 1.5 mm 3.25 mm pipetting robot inverted microscope 96-well chiller tips 45 mm 3D printed mold PDMS (Sylgard) poured mold Passive pumping design allows simple unpowered flow-cell compatible with vertical pipetting robot (Walker 2002) PASSIVE PUMPING FLOW CELL PROTOTYPE MOSAIC PLANNER - OPEN SOURCE ARRAY TOMOGRAPHY SOFTWARE REFERENCES AND GRANT SUPPORT COVERSLIP FLATNESS LASER ILLUMINATION time per 4 channel frame (sec) auto-focus filter-change exposure stage move Standard Upright Automated Microscope Zeiss Observer Z.1, 4 filter cubes, x-cite mercury halide liquid light guide IMAGING SPEED IMPROVEMENTS Improvement 16.1 sec per 4 images 892 images/hour hardware auto-focus (Rah et al. 2015) 100-400ms focus time ~2000 images/hour Estimated Speed Increase ~10-50 ms change time ~4000 images/hour quad band dichroic illumination switching sCMOS field size 4.2 vs 1.4 megapixels effectively 2.9x faster laser illumination ~5x power density ~12,000 images/hour NET IMPROVEMENT ~40x faster net imaging 500 nm X Y XY PSF 500 nm Z Y YZ PSF 50 100 1 nm/\u03bcm across 200 \u03bcm 500\u03bcm \u03bcmanager Core API hardware agnostic microscope commands images/status Camera Illumination Stage Microsc", "label": "poster"}
{"text": "ZENTRUM F\u00fcr nachhaltiges Forschungsdatenmanagement Literatur Huschka, Denis et al. (Hg.) (2013): Forschungsinfrastrukturen f\u00fcr die qualitative Sozialforschung. Berlin: Scivero. RatSWD (Hg.) (2018): Archivierung und Zugang zu qualitativen Daten. RatSWD Working Paper 267/2018. Berlin: Rat f\u00fcr Sozial- und Wirtschaftsdaten (RatSWD). https://doi.org/10.17620/02671.35 Steinhardt, Isabel et al. (2020): Das \u00d6ffnen und Teilen von Daten qualitativer Forschung. Ergebnisse eines Workshops der Forschungsgruppe \u201eDigitalisierung der Wissenschaft\u201c. Weizenbaum Series 6. Berlin: Weizenbaum Institute for the Networked Society. https://doi.org/10.34669/wi.ws/6 POSTER M\u00f6llenkamp, Andreas (2020): \u00d6ffnen und Teilen von Interviews. Ein Leitfaden. Zenodo. DOI: https://doi.org/10.5281/zenodo.3925304 Lizenz Dieses Werk ist lizensiert unter der Lizenz Creative Commons Attribution 4.0 International (CC BY 4.0): https://creativecommons.org/licenses/by/4.0/ PROJEKT Das Poster ist entstanden im Rahmen des Projekts Open Interviews. Auf dem Weg zur \u00d6ffnung qualitativer Interviewforschung. Weitere Informationen: https://w.wiki/Vkp Das Projekt wurde das 2018/2019 im Rahmen des Fellow-Programm Freies Wissen von Wikimedia Deutschland, dem Stifterverband f\u00fcr die Deutsche Wissenschaft und der VolkswagenStiftung gef\u00f6rdert. KONTAKT Andreas M\u00f6llenkamp Universit\u00e4t Hamburg Zentrum f\u00fcr nachhaltiges Forschungsdatenmanagement Monetastr. 4 20146 Hamburg Tel.: +49 40 42838-7231 andreas.moellenkamp@uni-hamburg.de www.fdm.uni-hamburg.de https://orcid.org/0000-0002-5750-0220 https://twitter.com/andreasmoellen21 Vorbereitung und Planung \uf0a7Bei Qualifikationsarbeiten: Sprechen Sie mit Ihren Betreuer*innen \u00fcber das Archivieren, \u00d6ffnen und Teilen von Interviews. Einen \u00dcberblick \u00fcber das \u00d6ffnen und Teilen von Daten qualitativer Forschung bietet Steinhardt et al. (2020). \uf0a7Reflektieren Sie, ob in Ihrem Projekt durch das \u00d6ffnen und Teilen ein Eingriff in den Forschungsprozess entstehen w\u00fcrde. Eine Beeinflussung der Interviewsituation k\u00f6nnen Sie umgehen, indem Sie Fragen der Archivierung und Zug\u00e4nglichmachung erst nach dem Interview besprechen, beispielsweise auf Grundlage des Interviewtranskripts.3 \u00d6FFNEN und Teilen von Interviews Ein Leitfaden \uf0a7Informieren Sie sich \u00fcber geeignete Forschungsdaten-Repositorien. Der Rat f\u00fcr Sozial- und Wirtschaftsdaten akkreditiert Forschungsdatenzentren: www.ratswd.de/forschungsdaten/fdz/ qualitativ \uf0a7Das Forschungsdatenzentrum Qualiservice hat sich auf die Archivierung und Bereitstellung von Interviews und anderen qualitativen Daten aus der Sozialforschung spezialisiert. Lassen Sie sich dort beraten und planen Sie Zeit und Kosten f\u00fcr die Archivierung ggf. in Ihrem F\u00f6rderantrag mit ein. www.qualiservice.org/ Illustrationen: digitalbevaring.dk (CC-BY 2.5 DK) Durchf\u00fchrung \uf0a7Dokumentation und Kontextualisierung: F\u00fcr eine gute Nachvollziehbarkeit und Nachnutzbarkeit ist eine m\u00f6glichst umfassende und prozessbegleitende Dokumentation und Kontextualisierung Ihrer Interviews wichtig. Dazu geh\u00f6ren die Mitglieder Ihres Forschungsteams, die Erl\u00e4uterung der Auswahl Ihrer Interviewpartner*innen, die Kommunikation vor dem Interview, der Kontext der Interviewsituation sowie die weiteren Bearbeitungs- und Auswertungsschritte. \uf0a7Datenschutz: Als Forscher*in sind Sie verpflichtet, verantwortungsvoll mit den personenbezogenen Daten Ihrer Interviewpartner*innen umzugehen. Nach der Datenschutz-Grundverordnung (DSGVO) d\u00fcrfen personenbezogene Daten nur f\u00fcr festgelegte, eindeutige und legitime Zwecke erhoben und verarbeitet werden. Dar\u00fcber hinaus sind die Landesdatenschutzgesetze f\u00fcr \u00f6ffentliche Hochschulen in Deutschland einschl\u00e4gig. Die Erhebung, Verarbeitung und Archivierung von personenbezogenen Daten bedarf daher der informierten Einwilligung Ihrer Interviewpartner*innen. \uf0a7Informierte Einwilligung: Die Einwilligungserkl\u00e4rung einer Interviewpartner*in setzt voraus, dass Sie sie \u00fcber Ihre Forschungsabsicht, das Vorgehen, die konkrete Nutzung der Daten und die Rechte der beforscht", "label": "poster"}
{"text": "Collaborative Research: Elements: ROCCI: Integrated Cyberinfrastructure for In Situ Lossy Compression Optimization Based on Post Hoc Analysis Requirements PIs: Sheng Di1,2, Franck Cappello1,2, Dingwen Tao3 1University of Chicago, 2Argonne National Laboratory 3 Indiana University Motivation Libpressio Z-Checker/QCAT Objectives This project aims to develop a Requirement-Oriented Compression Cyber-Infrastructure (ROCCI) for data-intensive domains such as astrophysics and materials science. The core purpose is practicality, enabling scientists to efficiently assess and/or optimize the lossy compression quality based on their post hoc analysis requirements. This project advances knowledge with three key thrusts: \u2022 It builds an efficient layer to interoperate with different lossy compressors and diverse post hoc analysis requirements on data fidelity by leveraging our developed compression adaptor library (LibPressio) and compression assessment library (Z-checker). \u2022 It develops an efficient engine to determine the best compressor with automatically tuned optimized settings. \u2022 It develops a user-friendly infrastructure integrating compression optimization and execution via HDF5 dynamic filter mechanism. Acknowledgement Z-checker is a parallel framework for assessing lossy compression of scientific data efficiently. QCAT is the corresponding lightweight utility library and toolkit. This research is supported by NSF OAC # 2104023 and 2104024. We acknowledge the computing resources provided on Bebop (operated by Argonne Laboratory Computing Resource Center and on Theta and JLSE (operated by Argonne Leadership Computing Facility). Publications Estimation error and cost of SECRE for SZx: When using a large sampling stride such as 40 (sampling rate would be 1/41\u22482.43%), the estimation error is still very low less than 1% in the worst case). System Architecture of ROCCI with improved & innovative modules. We are towards the end of the second year of the project. In the first two years, we have 20+ papers published in top conference/journal papers, including SC, ICDCS, ICDE, IPDPS, HPDC, ICS, VLDB, EuroSys, IJHPCA, HiPC, etc.. Major Accomplishments First year: We improved Libpressio to support 30+ compressors (both lossy and lossless, both CPU and GPU) and Z-checker/QCAT to support 40+ compression assessment metrics (including ratio, speed, max error, PSNR, SSIM, derivatives, distribution of errors, auto- correlation of errors, visualization, etc.) Second Year: We explored a series compression quality estimation methods, by leveraging machine learning (ML), statistical analysis, compression-principle analysis (surrogate), sampling method, etc. We also improved the performance for Libpressio, Z-checker/QCAT, SZ3, SZx, and developed new capabilities such as QoZ, FAZ. Libpressio-Predict Compression Ratio Estimation Evaluation using 4 real-world science datasets including climate simulation, cosmology research, large-eddy simulation, etc. LibPressio provides a productive interface for integrating compression. It eases experiment with new compressors with less code and complexity. Compression developers benefit from using a common implementation for a parallel compression; a CLI; Python, Rust, Julia, C, C++ bindings; and HDF5, ADIOS2, and other integrations that are complete and consistent with just 1 C++ class. 1 API 32+ compressors Builtin Provenance Support Optional Automatic Configuration and Optimization CPU Parallel and GPU Parallel Compressors Non-measurable overhead CLI, Python, Rust, Julia, C, and C++ bindings LibPressio addresses all these issues by providing a unifying interface with advanced engines for provenance and configuration optimization. LibPressio-predict integrates quite a few compression ratio and metric estimation algorithms for error-bounded lossy compression, including FXRZ, SECRE, Stats-based compresibility estimation method, etc. We have developed multiple efficient compression quality estimation methods and error-con", "label": "poster"}
{"text": "Innovative Research for a Sustainable Future www.epa.gov/research Keith Houck | houck.keith@epa.gov | 919-541-5519 Predicting Toxic and Therapeutic Mechanisms of the ToxCast Chemical Library by Phenotypic Screening Houck K1, Kleinstreuer N2, Yang J3, Berg E3, Knudsen T1, Richard A1, Martin M1, Reif D4, Judson R1, Polokoff M3 1 National Center for Computational Toxicology, Office of Research and Development, US EPA, Research Triangle Park, NC; 2ILS, Inc., Research Triangle Park, NC; 3BioSeek, a Division of DiscoveRx, South San Francisco, CA; 4NCSU, Raleigh, NC Abstract Summary Results \uf076The ToxCast Phase II library was screened in 8 complex cell culture systems measuring endpoints relevant to inflammatory signaling and vascular biology. \uf076Assays showed strong reproducibility across technical replicates and built-in test compounds. \uf076The BioMAP system identified potential targets, modes of action, and clinical side effects for compounds based on the reference database. \uf076Assays provided coverage of mechanisms/targets not directly represented in assay endpoints, e.g. AhR \uf076Phenotypic screening and computational analysis provides a unique opportunity to survey environmental chemicals for potential human bioactivity Methods Addressing safety aspects of drugs and environmental chemicals relies extensively on animal testing. However the quantity of chemicals needing assessment and challenges of species extrapolation require development of alternative approaches. Using 8 primary human cell systems (BioMAP), we screened in concentration-response format 776 chemicals from the ToxCast Phase II library (http://epa.gov/ncct/toxcast/chemicals.html) for perturbation of physiologically important pathways. Cell systems consisted of combinations of endothelial, peripheral blood mononuclear, bronchial epithelial and coronary artery smooth muscle cells; fibroblasts and keratinocytes. Chemical-response signatures from 87 endpoints covering molecular functions relevant to toxic and therapeutic pathways were generated. Assessment of profiling data by unsupervised clustering using Self Organizing Maps and supervised analysis using Support Vector Machine algorithms grouped chemical/concentration by potential mechanism class providing insight into polypharmacology and potential off-target effects of drugs. Clusters contained diverse mechanistic activity including kinase, TNF\u03b1, phosphodiesterase and Hsp90 inhibitors; Ah, estrogen and glucocorticoid receptor modulators; disruptors of mitochondrial and tubulin function; histamine antagonists; and statins. Novel associations identified included induction of tissue factor in endothelial cells by ER antagonists, AhR agonists and mTOR inhibitors, all chemical classes with susceptibility to venous thrombosis. Further, structure-based analysis demonstrated associations between chemical categories and mechanism class predictions. Our results yielded an extensive list of potential toxicological targets and biological pathways that we are incorporating into a chemical prioritization strategy for chemicals of concern to the Agency. Objective Use primary human cell phenotypic responses to classify and predict compound mechanisms of action and potential toxicities Primary Cell Systems Used SVM Models and Top Scoring Compounds \u2022 Compounds were tested at 4 (or 8) concentrations in duplicate, 200 mM high concentration with half-log dilutions. \u2022 Cells treated with compounds followed at one hr by stimulation of signaling pathways \u2022 Cells harvested at 24 hr and endpoints measured by ELISA or staining (SRB) \u2022 Data normalized to log10 Fold Change over DMSO controls \u2022 AC50 values calculated using 4-parameter Hill model \u2022 Compounds tested in blinded fashion and included internal replicates \u2022 Predictive models for 28 mechanism classes were built using a two class approach with SVM using R SVM package e1071 (Berg et al., JBS 18:1260, 2013). \u2022 Unsupervised clustering of all compounds at the individual concentration level was conducted", "label": "poster"}
{"text": "Key partners: Sewer Mining (SM) technology is a mobile wastewater treatment system in containers able to extract wastewater from local sewers, treat it directly and reuse at the point of demand in dense urban environments. The unit consists of a membrane bioreactor unit (MBR) and a UV disinfection component and produces high quality reclaimed water for irrigation and for aquifer recharge during the winter. The SM unit has an annual capacity of about 9.000 m3 of reclaimed water Treatment residuals are collected, treated locally in the site and are transformed to an eco-friendly fertilizer (compost), when merged with green waste from pruning. Implemented technology The technology has been tested for over 1.5 year. Sampling and analysis activities have been implemented at a weekly basis and the main results that are illustrated in the table and the diagrams are summarized below: \u2022 SM produces water of a quality that meets all national and international criteria for unrestricted irrigation and urban use \u2022 Achieves complete elimination of organic carbon and pathogenic content \u2022 Provides reduction of pathogens due to MBR filtration process (without addition of chemicals avoiding production of secondary pollutants) \u2022 UV disinfection unit showed great performance \u2022 System works automatically and is remotely monitored in terms of operation and quality performance. Parameters Influent Effluent after UV disinfection Legislation Limits TSS 253\u00b1 97 \u2264 2 for 80% of samples \u22642 for 80% of samples \u226410 for 80% of samples BOD5 216 \u00b1 64 8,6 \u00b1 2,4 3 \u226410 for 87% of samples \u226410 for 80% of samples COD 695 \u00b1 97 24,2 \u00b1 4,1 3 - TN 81 (average) 5,5 \u00b1 1,4 3 \u2264 15 NH4-N 5 \u00b1 3 0,2 \u00b1 0,19 3 \u2264 2 TP 10 \u00b1 1.4 1,57 (average) - Turbidity - 2 (median) \u2264 2 (median) Conductivity 1,109 \u00b1 75 1,067 \u00b1 0 - pH 7.1 \u00b1 0,2 7.5 \u00b1 0,3 - TC >10 2 for 80% of samples 9 for 95% of samples \u22642 for 80% of samples \u226420 for 95% of samples FC >10 \u22643 - EC >10 \u2264 3 for 95% of samples \u22645 for 80% of samples \u226450 for 95% of samples Sewer Mining (SM) technology as a Distributed Intervention for Water-Energy-Materials in the Circular Economy: A Real World Demonstration in the Athens Plant Nursery Klio Monokrousou1, Christos Makropoulos1, Konstantinos Tsimnadis2, Georgios Katsouras3, Nikolaos Tsalas3 1. Department of Water Resources and Environmental Engineering, School of Civil Engineering, National Technical University of Athens, Heroon Polytechneiou 5, Zografou, 15780, Greece, kmonokrousou@gmail.com; cmakro@mail.ntua.gr 2. City of Athens, Department of Greenery and Urban Fauna, 5 Panag. Kanellopoulou, 11525 Athens, Greece, tsimnad@yahoo.gr 3. Athens Water Supply and Sewerage Company S. A (E.YD.A.P.) \u2013 Research and Development \u2013 156 Oropou 11 str., 11146, Galatsi, Athens, Greece, gekats@eydap.gr; ntsal@eydap.gr Methodology Results The sewerage is extracted through two pumps that work alternately, from about four meters below the surface to fill in a buffer tank. The process starts when filtered wastewater enters a denitrification tank, where anaerobic microorganisms turn nitrates to nitrogen gas which naturally leaves the system. The denitrification tank communicates with a nitrification or aeration tank, where aerobic microorganisms turn reduced nitrogen compounds to nitrates. Subsequently, the biologically treated wastewater is transferred to the membrane tank and then the permeate passes through the UV disinfection unit and the final disinfected product flows naturally toward a storage tank to be reused mainly for irrigation purposes. The whole process is fully monitored through sensors and is automated using pneumatic actuated valves controlled by a PLC unit. The excess sludge produced from the SM unit along with the green and wood waste of the urban green spaces that end up in the Nursery, goes through a rapid composting process to produce on-site fertiliser. A heat exchanger and heat pump system recovers thermal energy from the wastewater to be reused for the technological processes of the c", "label": "poster"}
{"text": "Ruta alternativa Barranco Jabal\u00ed Ruta alternativa Trincheras Sendero Acequias de Paulo y El Coto Usted est\u00e1 aqu\u00ed Mapa propiedad del Instituto Geogr\u00e1fico Nacional El municipio alpujarre\u00f1o de P\u00f3rtugos, ubicado en el macizo granadino de Sierra Nevada, destaca por sus diversas fuentes y manantiales que abastecen de agua una importante red de acequias hist\u00f3ricas. Estos nacimientos de agua se enriquecen con los aportes nivales y permiten dotar al municipio de abundante agua. Estos sistemas de riego existen, al menos, desde \u00e9poca andalus\u00ed y han generado numerosos espacios de cultivo, pastos y han modelado el paisaje, haciendo de este, un espacio singular. En En el caso del sendero Acequias de Paulo y El Coto, podremos apreciar, transitando por el camino de servidumbre de paso de la acequia, parte de un sistema ancestral de manejo de agua. Estas acequias, toman las aguas del r\u00edo Jabal\u00ed y recorren zonas de alta monta\u00f1a, gui\u00e1ndola hasta puntos muy concretos donde se \u201ccarea\u201d. Esto, signi\u00f6ca la in\u00f6ltraci\u00f3n del agua en la tierra de manera arti\u00f6cial, para recogerla, en zonas m\u00e1s bajas, un tiempo despu\u00e9s. A trav\u00e9s de diferentes puntos de inter\u00e9s, podremos aprender sobre estos regad\u00edos de alta monta\u00f1a: la gesti\u00f3n y mantenimiento por parte de las comunidades de regantes, sus bene\u00f6cios ambientales, infraestructuras asociadas a estas y otros elementos con los que nos encontraremos a lo largo del recorrido (m\u00e1s informaci\u00f3n en el c\u00f3digo QR). Visitaremos un espacio alterado por el ser humano tradicionalmente, pero que respeta de manera equilibrada y e\u00f6ciente el medio en el que se encuentra. RECUERDE: Mant\u00e9ngase Evite hacer ruido Respete los bienes y Mantenga limpio No se permite No se permite la No se permite la No se permite la en los caminos propiedades privadas este entorno encender fuego recolecci\u00f3n de plantas captura de animales recolecci\u00f3n de f\u00f3siles 2 2 2 3 DATOS T\u00c9CNICOS: Tipo de sendero: Semi-circular Distancia del recorrido: 7,3 km Desnivel acumulado de subida: 503 m Desnivel acumulado de bajada: 503 m Tiempo estimado del recorrido: 3 h y 10 min. Se\u00f1alizaci\u00f3n de Sendero Local (SL) Acequia El Coto I Acequia de Paulo Panor\u00e1mica de P\u00f3rtugos Sendero ACEQUIAS DE PAULO Y EL COTO (P\u00d3RTUGOS) SL-A 386 Ayuntamiento de P\u00f3rtugos https://regadiohistorico.es", "label": "poster"}
{"text": "U.S. Environmental Protection Agency Office of Research and Development EPA www.epa.gov \u25baComparison of the HT-H295R screening data analyzed by ANOVA with the summary results available from the OECD validation study suggests that the HT-H295R assay predicted T and E2 effects well. \u25baThe maxmMd is a reproducible and quantitative metric to determine the magnitude of chemical perturbation of steroidogenesis in HT-H295R, representing a data-driven option for evaluating lists of chemicals. \u25baThe number of steroid hormone significantly perturbed in the HT-H295R assay does not indicate the magnitude of effect on steroidogenesis, whereas the maxmMd can differentiate strong and weak modulators of steroidogenesis. \u25baSelectivity scoring is a useful method to filter HT-H295R pathway positives for additional screening. \u25baFuture work will include more comprehensive benchmarking of the maxmMd metric, and further adapting the HT- H295R kinetic model based on time-course experiments. We use Mahalanobis distance to quantify disruption of steroidogenesis across 11 steroid hormone measurements. Mahalanobis distance incorporates the effect size for each steroid hormone measure after adjusting for covariance between the steroid hormone measures. Evaluating Perturbation of In Vitro Steroidogenesis Using a High-throughput H295R Assay Derik E. Haggard1,2, Agnes L. Karmaus1,2,3, Matt T. Martin2,4, Richard S. Judson2, R. Woodrow Setzer2, Katie Paul Friedman2 1ORISE Postdoctoral Research Participant 2National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency 3Currently at Integrated Laboratory Systems, Inc 4Currently at Drug Safety Research and Development, Global Investigative Toxicology, Pfizer Derik E. Haggard l haggard.derik@epa.gov l 919-541-0745 Background: Endocrine disruption is a toxicity of both physiological and regulatory importance; as steroid hormones regulate reproduction, development, and other biological processes, it is a priority to identify chemicals that may interact with production of these hormones. A high-throughput H295R assay (HT-H295R) was developed as part of the U.S. EPA\u2019s ToxCast program that includes measurement of 11 hormones across the steroid hormone biosynthesis pathway expressed in H295R cells, including progestagens, corticosteroids, androgens, and estrogens. HT-H295R Screening: 2012 chemicals in single concentration screening, 656 in concentration-response. Objectives: \u25baDemonstrate that the HT-H295R assay may be used to predict testosterone (T) and estradiol (E2) production via comparison of the 25 reference chemicals in the OECD-validated H295R assay. \u25baDevelop a statistical analysis that integrates data from 11 steroid hormones into a single numeric value that indicates the magnitude of effect on steroidogenesis in the HT-H295R assay. \u25baBegin development of a pathway-based kinetic model of steroidogenesis in HT-H295R. This poster does not reflect US EPA policy. D.E.H. was supported by appointment to the Research Participation Program of the U.S. Environmental Protection Agency, Office of Research and Development, administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and the U.S. EPA. \u25baA total of 107 chemicals were replicated across multiple blocks; of these, 94 chemicals (87.9%) had concordant maxmMd pathway responses. \u25bamaxmMd values were compared to the sum of steroid hormone hit counts, as measured by ANOVA. \u25baThe maxmMd provides a quantitative indicator of activity that can distinguish chemicals that exert different magnitudes of effect on steroidogenesis but have the same hit count. Effect Sensitivity Specificity Accuracy Testosterone up 1.00 0.89 0.90 Testosterone dn 0.67 0.92 0.83 Estradiol up 0.75 0.83 0.80 Estradiol dn 0.80 1.00 0.95 Left: The residual covariances of many hormone measures in HT-H295R are highly correlated. Middle: Example of Euclidean distance for correlated", "label": "poster"}
{"text": "Towards cell-inspired particle-based microrobots: Optimisation of the encapsulation of microparticles in lipid membranes Eugenia De Remigis1, Gaia Petrucci1, Elisa Roberti1, Dario Cecchi1, Hilda Gomez Bernal1, Elisa L. Petrocelli2, Jyoti Sharma1 , Francesco Bianciardi1 and Stefano Palagi1 1) The Biorobotics Institute, Scuola Superiore Sant\u2019Anna, Pontedera (Pisa), Italy 2) Sapienza University of Rome (Rome), Italy Confinement of active matter can lead to the emergence of peculiar collective behaviour and interaction with the confining structure1,2. Encapsulating microscale active particles in flexible vesicles can be the basis for artificial active systems to study or emulate complex biological phenomena. ERC project CELLOIDS aims to employ this concept to fabricate soft, deformable and intelligent microrobots for medical applications, inspired by the amoeboid migration strategy of human leukocytes. Particle density has been shown to be crucial for the emergence of collective behaviour3,4. 1. Song, S. et al., J. Am. Chem. Soc. 144, 2022. 2. Vutukuri, H. R. et al., Nature 586, 2020. 3. Bricard, A. et al., Nature 503, 2013. 4. Buttinoni, I. et al., Phys. Rev. Lett. 110, 2013. 5. Pautot, S. et al., Langmuir 19, 2003. 6. Moga, A. et al., ChemBioChem 20, 2019. 7. Ghellab, S. E. et al., Biophys Chem 253, 2019. 8. NIST/SEMATECH e-Handbook of Statistical Methods, http://www.itl.nist.gov/div898/handbook/, accessed April 11, 2023. 9. Sakamoto, R. et al., Proceedings of the National Academy of Sciences 119, 2022. Icons from: Bioicons - high quality science illustrations Data analysis: ImageJ, Rstudio References Acknowledgements This work has been supported by the European Research Council under Grant Agreement No. 948590, project \u201cCELLOIDS\u201d. Further information Do not hesitate to contact us! eugenia.deremigis@santannapisa.it PI: stefano.palagi@santannapisa.it @MicroRobotLab @microrobot.lab Microscale Robotics Laboratory Optimization of microparticle encapsulation Objective 1: obtain controllable particle density Goal: design a bioinspired strategy to employ active microparticles as a propulsion system for ultra-deformable, autonomous microrobots. flexible membrane active core gives ultra- deformability and responsiveness allows for self- propulsion Fabrication of particle-loaded, phospholipid-based giant unilamellar vesicles (GUVs) by inverted emulsion method5,6 Critical process parameters \u2022 particle concentration in inner suspension \u2022 centrifugation acceleration and time Major issue: polydispersity in vesicle size and particle density Future directions Analysis: response surfaces7,8 Phase-contrast microscopy Motility of amoeboid model systems derives from the interaction with a confining environment9. Fabrication of GUVs encapsulating PS@Pt Janus microparticles A B Infiltration of empty/full GUVs in restrictive chambers Particle-loaded GUVs in confinement Objective 2: verify activity and stability GUVs + PS@Pt Janus microparticles in unconfined environment GUVs in hypertonic solution form protrusions, where active particles can move. Confinement of the GUV in an asymmetric restrictive environment Functionalisation of membrane phospholipids and Janus microparticles to induce contraction-based propulsion How to obtain directional movement of the GUV by exploiting the spontaneous behaviour of Janus microparticles? Activity Stability & Deformability contraction-based extension-based Response parameters \u2022 vesicle size \u2022 particle density combined Conclusions Objective 1: Results suggest that high particle concentration in the inner suspension helps obtain bigger and fuller GUVs. Long centrifugation time and high acceleration seem necessary to maximise GUV dimension; on the other hand, very high acceleration values could prove counterproductive for an efficient encapsulation. The optimal trade-off point is likely still outside the tested domain. hypertonic glucose solution 3% H2O2 in hypertonic glucose solution GUV suspension 1 2 3 no confineme", "label": "poster"}
{"text": "\u2022 Internationale Konferenzen zu historischer Datenkritik \u2022 Blog \"Historical method under digital conditions\" \u2022 Epochenspezifische Lehrpl\u00e4ne \u2022 Buch \"Historical Data Criticism and Sustainable RDM\" \u2022 Rechtliche Empfehlungen \u2022 Informationsdienst zu technischen Trends und Normen in anderen L\u00e4ndern \u2022 Empfehlungen zu Datenkritik und FDM \u2022 White Paper zu ethischen Dimensionen in den Area Histories im digitalen Raum The Future of the Past Task Area \"Data Literacy\" \u2022 Data Literacy Bedarfserhebung \u2022 Regional Training Centers \u2022 Virtueller Beratungsservice \u2022 Virtuelle Trainingskurse \u2022 Data Literacy Schulungskata\u00adlog \u2022 Modell Curriculum \u2022 Lernmodule & Schulungsmaterialien \u2022 Pilotprogramm f\u00fcr Multiplikator:innen \u2022 Governance-Modell f\u00fcr Data Literacy Material-Akkreditierung Unsere Arbeitsfelder Data Literacy Bedarfserhebung Start \"von B\u00fcchern zu Bytes\" Publikation Fragebogendesign Internationale Konferenz \"Epistemic Virtues in Digital History and Humanities\" Start der Blogreihe \"Was Historiker:innen und historisch Arbeitende ihrem j\u00fcngeren Ich raten w\u00fcrden\" Publikation \u201eDigital Monolingualism, Archives at Risk, and Global Views on Open Access\u201c Bereitstellung Data Literacy Bibliographie Gr\u00fcndung AG \"Regional Training Centers\" Kooperationsworkshop zu OER Sammlung von Data Literacy Lern- und Lehrmaterialien Mitwirkung Konzeption NFDI-Workinggroup \"Helpdesks\" Publikation Umfragebericht Data Literacy Bedarfe Ver\u00f6ffentlichung Data Literacy Trainingskatalog Publikation Whitepaper Data Literacy Kompetenzprofil Gr\u00fcndung AG \"Data Literacy in der Lehre\" Roundtable auf der CrossArea-Tagung zum Thema \"The Future of the Archive(s)\" 4memory.de | @NFDI4memory | 4memory@ieg-mainz.de gef\u00f6rdert durch Projektnummer 501609550 Mailingliste: E-Mail: contact@4memory-dataliteracy.de Wir sind eng vernetzt Auf dem Laufenden bleiben Ver\u00f6ffentlichungen auf Zenodo \"Von B\u00fcchern zu Bytes\" Veranstaltungsreihe auf YouTube Data Literacy Data Literacy Ausbildung Ausbildung Historische Historische Quellenkritik Quellenkritik & FDM & FDM Digitale Area Digitale Area Histories Histories 2023 2024 Dienste f\u00fcr Dienste f\u00fcr digitale digitale Forschung Forschung Workshop & Publikation \"Area Histories und die NFDI4Memory: Zur Rolle der FID\"", "label": "poster"}
{"text": "1 Online supplement for integrated production-transportation planning for supply chain with perishable food and shared returnable transport items APPENDIX A: THE FRAMEWORK OF THE DIFFERENTIAL EVOLUTIONARY ALGORITHM The framework of the differential evolutionary algorithm (DEA) is shown in Fig 1. The basic iteration process of the DEA is similar to other evolutionary algorithms, such as genetic algorithms. It starts with a randomly generated population of candidate solutions and iteratively improves these solutions through mutation, crossover, and selection operations, aiming to converge toward the global optimal solution. The main steps of the DEA are as follows: first, we randomly generate enough individuals as an initial population; second, in mutation operation, two individuals are randomly selected from the current population. A weighted difference vector is calculated between these individuals and added to a third individual to create a new individual; third, the crossover operation crosses the original individual and the mutated individual to generate a new individual; then, in the selection operation, individuals with better fitness values are selected for the next-generation population. For more details on the DEA, please refer to Kumar et al. [1]. Population initialization Stopping condition is satisfied No Mutation Crossover Selection Output the best optimal solution Yes Fig. 1. The framework of differential evolutionary algorithm. APPENDIX B: THE FRAMEWORK OF THE COLUMN GENERATION The framework of the column generation (CG) algorithm is represented in Fig 2. To apply the CG to our problem P1, we reformulate it appropriately into a set partitioning model (master problem MP) and |M| subproblems. At the initial iteration of the CG, we solve a smaller-scale restricted master problem RMP (i.e., with fewer variables than the original problem MP). Then, we solve the relaxation of RMP, calculate the dual value (i.e., shadow price) for each constraint, and input dual values into subproblems. Subsequently, subproblems are solved to check the variables that are not currently considered in the RMP to see if there are any variables that can reduce the total cost (i.e., their reduced cost, denoted as RC, is less than zero). If such variables are found, we add them to the RMP and return to solve RMP. This process is repeated until no new variables can enter the RMP to reduce the total cost (i.e., the RC is non-negative). For more details on the CG, please refer to Tempelmeier [2].", "label": "poster"}
{"text": "AN\u00c1LISE GEOESPACIAL E TEMPORAL DOS INDICADORES DE ALTA COMPLEXIDADE EM SA\u00daDE NO ESTADO DE S\u00c3O PAULO Breno Bologna, Laura Lopes Amaral, Ana Paula Romani, Larissa Mayumi Yokoi, Tiago Ribeiro de Oliveira, Harki Tanaka, Priscyla Waleska Sim\u00f5es Curso de Engenharia Biom\u00e9dica, Programa de P\u00f3s-Gradua\u00e7\u00e3o em Engenharia Biom\u00e9dica Centro de Engenharia, Modelagem e Ci\u00eancias Sociais Aplicadas Universidade Federal do ABC / Santo Andr\u00e9, Brazil 1. INTRODU\u00c7\u00c3O Procedimentos de alta complexidade s\u00e3o destinados a situa\u00e7\u00f5es espec\u00edficas e mais raras, entretanto o impacto financeiro desse tipo de procedimento \u00e9 alto. Assim, essa pesquisa visa apresentar a taxa de interna\u00e7\u00f5es de alta complexidade no Estado de S\u00e3o Paulo de forma a prover informa\u00e7\u00f5es importantes para a gest\u00e3o de sa\u00fade p\u00fablica. 2. METODOLOGIA Estudo descritivo que utilizou dados secund\u00e1rios do Sistema de Informa\u00e7\u00f5es Hospitalares (SIH/SUS), extra\u00eddos do TabNet/DATASUS distinguindo entre as macrorregi\u00f5es e microrregi\u00f5es do Estado de S\u00e3o Paulo, e entre os munic\u00edpios da microrregi\u00e3o de S\u00e3o Paulo. Foram obtidas as interna\u00e7\u00f5es de alta complexidade de 2008 a 2016, por local de resid\u00eancia e por grupos de procedimentos. Al\u00e9m disso a popula\u00e7\u00e3o de cada uma dessas regi\u00f5es foi extra\u00edda do IBGE. Determinou-se assim a taxa bruta de interna\u00e7\u00f5es de alta complexidade a cada mil habitantes para cada regi\u00e3o. A partir deste indicador foi estimada a m\u00e9dia, o desvio padr\u00e3o e foram realizadas an\u00e1lises da evolu\u00e7\u00e3o hist\u00f3rica. Al\u00e9m disso foram realizados c\u00e1lculos de regress\u00e3o linear, e estimados o coeficiente angular, o n\u00edvel de signific\u00e2ncia e o coeficiente de determina\u00e7\u00e3o. Em todas as an\u00e1lises, considerou-se como estatisticamente significativo p<0,05. 3. RESULTADOS A s\u00e9rie hist\u00f3rica evidencia que a m\u00e9dia do Estado de SP aumentou nesses \u00faltimos anos, e ao observar as microrregi\u00f5es com maiores e menores taxas, Barretos e Franco da Rocha, nota-se que o aumento foi distribu\u00eddo entre as regi\u00f5es (Figura 1 e Figura 2). O procedimento que resultou em maiores taxas de interna\u00e7\u00e3o de alta complexidade foi a Cirurgia, com taxa m\u00e9dia bruta de 2,8 e aumento ao longo dos anos. Os procedimentos cl\u00ednicos, transplantes e procedimentos com finalidade diagn\u00f3stica revelaram taxas de 0,6; 0,4 e 0,1 interna\u00e7\u00f5es a cada 1.000 habitantes, respectivamente, com poucas oscila\u00e7\u00f5es no per\u00edodo. 4. CONCLUS\u00c3O O presente estudo resultou em indicadores que servem de insumo para decis\u00f5es dentro da gest\u00e3o p\u00fablica baseada em evid\u00eancias principalmente quanto \u00e0 distribui\u00e7\u00e3o espacial de quem usa esse tipo de servi\u00e7o. Futuras pesquisas devem investigar os indicadores e estat\u00edsticas associadas. Figura 1. Evolu\u00e7\u00e3o Temporal das Taxas de Interna\u00e7\u00e3o por Microrregi\u00e3o/SP No per\u00edodo entre 2008 a 2016, foram realizadas 1.537.476 interna\u00e7\u00f5es de alta complexidade no Estado de SP, o que equivale a uma taxa bruta m\u00e9dia de 4,0 interna\u00e7\u00f5es a cada 1.000 habitantes CONTATO Profa Dra Priscyla Waleska Sim\u00f5es - pritsimoes@gmail.com Curso de Engenharia Biom\u00e9dica / Programa de P\u00f3s-Gradua\u00e7\u00e3o em Engenharia Biom\u00e9dica / Centro de Engenharia, Modelagem e Ci\u00eancias Sociais Aplicadas/ Universidade Federal do ABC / S\u00e3o Bernardo do Campo (SP) / Brasil Figura 2. Distribui\u00e7\u00e3o Geogr\u00e1fica das Taxas de Interna\u00e7\u00e3o (p/ 1.000 hab) por Microrregi\u00e3o/SP (a) e Macrorregi\u00e3o/SP (b)", "label": "poster"}
{"text": "RESEARCH POSTER PRESENTATION DESIGN \u00a9 2015 www.PosterPresentations.com Studied areas in coastal zone for SST and the preparation of the TRISHNA mission: The Mediterranean sea along the coast from the Bay of Banyuls/Mer up to Marseille : \u2192 Submesoscale processes (~ 1-10km) (link with the SWOT mission) up to the scale of mixing/dissipation (100 m-1km): \u2192 Diurnal cycle, mixing after a wind event, river discharge and plumes, groundwater discharges especially around the in situ observations for the SST: moorings (LF/HF) examples: in the Bay of Banyuls/Mer (this poster), lagoons \u2022 C\u00f4te Sud-Nord avec un canyon \u2192 difference (Airborne SST/Landsat SST \u2013 HF in situ SST) = - 0.5\u00b0C (POEM Station) And = -1\u00b0C (SOLA Station) \u2192 Difference (satellite SST at 9:20am \u2013 Airborne SST at 10am) = - 0.1\u00b0C Laboratoire d\u2019Etudes en G\u00e9ophysique et Oc\u00e9anographie Spatiales \u2013 Toulouse \u2013 F - France I. Dadou, B. Pagli, M. Kaouah (LEGOS, Toulouse, F)M. Irvine (INRAE, Bordeaux, F) B. Coudert, V. Rivalland (CESBIO, Toulouse, F) R. Villemain, L. Zudaire (LOMIC/OOB, Banyuls/Mer, F) F. Bourrin (CEFREM, Perpignan, F) Sea surface temperature (SST) in coastal ocean with different data: application for the TRISHNA mission Scientific context Scientific context Study thermal infrared signals (TIR) for the determination of sea surface temperature (SST) in the coastal environment (Mediterranean Sea) by different data (airborne, satellite, in situ data, model outputs) and methods, complementary in their spatio-temporal resolutions and coverage in order to prepare the TRISHNA mission (CNES/ISRO - 2025) (algorithm, products and expectations in coastal environment) Main scientific question Main scientific question Studied Area: Mediterranean Sea Studied Area: Mediterranean Sea SST data and models used with different spatial resolution SST data and models used with different spatial resolution Conclusion & perspectives Conclusion & perspectives References References Results Results Berk, A. et al. MODTRAN 5: a reformulated atmospheric band model with auxiliary species and practical multiple scattering options: update. In Proceedings of the Algorithms and Technologies for Multispectral, Hyperspectral, and Ultraspectral Imagery XI ; International Society for Optics and Photonics, 2005; Vol. 5806, pp. 662\u2013667.Estournel, C., Marsaleix, P., & Ulses, C. (2021). A new assessment of the circulation of Atlantic and Intermediate Waters in the Eastern Mediterranean. Progress in Oceanography, 198, 102673. Estournel, C., X. Durrieu de Madron, P. Marsaleix, F. Auclair, C. Julliand, and R. Vehil (2003) Observation and modeling of the winter coastal oceanic circulation in the Gulf of Lion under wind conditions influenced by the continental orography, (FETCH experiment), J. Geophys. Res., 108(C3), 8059, doi:10.1029/2001JC000825, 2003 Feuilloley G. , Fromentin J-M, Stemmann L., Demarcq H, Estournel C, Saraux C. (2006), Concomitant changes in the environment and small pelagic fish community of the Gulf of Lions, Progress in Oceanography, Volume 186, 2020 Gatti, J., Petrenko, A., Devenon, J. L., Leredde, Y., & Ulses, C. (2006). The Rhone river dilution zone present in the northeastern shelf of the Gulf of Lion in December 2003. Continental Shelf Research, 26(15), 1794-1805. Lagouarde, J.-P., M. Bach, J.A. Sobrino, G. Boulet, X. Briottet, S. Cherchali, B. Coudert, I. Dadou, G. Dedieu, P. Gamet, O. Hagolle, F. Jacob, F. Nerry, A. Olioso, C. Ottl\u00e9, (2013). The MISTIGRI thermal infrared project: scientific objectives and mission specifications. International Journal of Remote Sensing. Volume 34, Issue 9-10, pages 3437-3466 O\u2019Carroll, A. G., Armstrong, E. M., Beggs, H. M., Bouali, M., Casey, K. S., Corlett, G. K., ... & Wimmer, W. (2019). Observational needs of sea surface temperature. Frontiers in Marine Science, 6, 420. Schaeffer, A., Garreau, P., Molcard, A., Frauni\u00e9, P., & Seity, Y. (2011). Influence of high-resolution wind forcing on hydrodynamic modeling of the Gulf of Lions. Ocean Dynamics, 61(11)", "label": "poster"}
{"text": "Introduction Chronic hepatitis B infection (CHB) has diverse disease phenotypes, ranging from minimal hepatic fibrosis, to cirrhosis and hepatocellular carcinoma (HCC)1. Serum viral markers are currently measured to inform clinical management, however none directly detect the covalently closed circular DNA (cccDNA) hepatocyte reservoir. Serum hepatitis B core related antigen (HBcrAg) has been correlated with cccDNA levels, and may predict HCC development2,3, but most studies are from Asia where genotypes B and C predominate4-6, so wider utility of HBcrAg is unknown. Serum Hepatitis B core-related antigen in a diverse UK cohort of patients with Chronic Hepatitis B infection Louise O Downs1,2, Tingyan Wang1,3, Marion Delphin4, Elizabeth Waddilove4, Monique Andersson2, Geoffrey Dusheiko5, Kosh Agarwal5, Eleanor Barnes1,2 Ivana Carey5, and Philippa C Matthews1,4,6,7 1 Nuffield Department of Medicine, University of Oxford, UK, 2 Department of Infectious Diseases and Microbiology, John Radcliffe Hospital, Oxford, UK, 3 NIHR Oxford Biomedical Research Centre, University of Oxford, UK, 4 The Francis Crick Institute, London, UK, 5 Institute of Liver Studies, King\u2019s College Hospital, London, UK, 6 Division of Infection and Immunity, University College London, UK, 7 Department of Infectious Diseases, University College London Hospital, London, UK Contact Informations: Louise Downs: louise.downs@exeter.ox.ac.uk @lou_downs Philippa Matthews: philippa.matthews@crick.ac.uk @pippa_matt References 1 GBD 2019 Hepatitis B Collaborators, 2022 (PMID: 35738290) 2 Testoni et al, 2019 (PMID:30529504) 3 Carey et al, 2020 (PMID: 31701544) 4 Tada et al, 2018 (PMID: 28914957) 5 Tada et al, 2016 (PMID: 27034253) 6 Shimakawa et al, 2020 (PMID: 31102406) Aims We measured HBcrAg in a cross-sectional cohort of 143 ethnically diverse adults with CHB from a UK teaching hospital to understand how HBcrAg varies or is associated with: Patient demographics. Liver disease. Treatment Its use as a surrogate HBV DNA marker will also be investigated and whether this applies in all subgroups. Methods Clinical Metadata Patient data were collected in outpatient clinics and from Oxford University Hospitals Electronic Patient Records (EPR). 143 patients infected with HBV enrolled in the Oxford University Hospitals NHS Foundation with broad Viral Loads (VL). Participants provided written informed consent. Serum samples Liver Biomarkers (Alanine Transferase - ALT) HBV Biomarkers (HBeAg, HBsAg, VL) HBcrAg: chemiluminescent assay (Lumipulse G HBcrAg assay, Fujirebo) Statistical analysis was conducted in R (version 4.1.1) using the \u2018ggplot2\u2019 package (version 3.3.6). Correlations were all done using Pearson\u2019s coefficient. Acknowledgments: Oxford University Hospitals laboratories NIHR Health Informatics Collaborative Kinga A V\u00e1rnai and Oliver Freeman Results Figure 1: HBcrAg correlation with patients metadata HBcrAg was significantly correlated with HBsAg (A-B) and HBV DNA levels (D-E), however this was lost with HBeAg negativity (C,F). HBcrAg was still detected in those with undetectable HBV DNA. HBcrAg did not correlate with ethnicity (A), biological sex (B) or treatment (C) but is positively correlated with serum ALT (D) and decline significantly with age (E). 2 4 6 8 0 100 200 300 ALT (IU/L) HBcrAg (U/mL) 2 4 6 8 20 40 60 Age (years) HBcrAg (U/mL) E D 2 4 6 8 Arab Asian Black African Chinese European Other Asian Unknown HBcrAg (U/ml) A Ethnic group 2 4 6 8 Female Male HBcrAg (U/ml) B Biological Sex Figure 2: HBcrAg correlation with viral parameters in patients 4 6 8 0 2000 4000 HBsAg (IU/ml) HBeAg positive patients B 2 3 4 5 0 2000 4000 6000 HBeAg negative patients C A 2 4 6 8 0.0 2.5 5.0 7.5 HBcrAg (U/mL) All Patients D 4 6 8 0.0 2.5 5.0 7.5 HBV DNA (log IU/mL) HBeAg positive patients E 2 3 4 5 0 2 4 HBeAg negative patients F HBcrAg (U/mL) All Patients 2 4 6 8 No Yes HBcrAg (U/ml) Treatment status C 0.0 2.5 5.0 7.5 0 2000 4000 6000 R = - 0.19 p = 0.023 R = - 0.42 p = 0.047 R =", "label": "poster"}
{"text": "hhu.de Cyanobacteria as platform organisms for biotechnology Cyanobacteria are photoautotrophic bacteria capable of photosynthesis and high rates of CO2 fixation. Their metabolic potential makes them promising candidates for biotechnological production of industrially relevant compounds such as plant secondary metabolites. Valencene - an important aroma and more Valencene is a sesquiterpene that can be found in many citrus fruits. While it can be used in various applications in industry, including cosmetics and flavor, it also serves as a precursor for nootkatone, which has been shown to act as a powerful insect repellant, but can also inhibit growth of cancer cells. ValenCell: Large-scale production of sesquiterpenes from microalgae Anna Behle1, Ilka Axmann1, Lars B\u00e4hr2, Arne W\u00fcstenberg2 CO2BioTech Kick-Off Meeting Lars B\u00e4hr (CellDEG) Anna Behle (HHU) Heinrich-Heine-Universit\u00e4t D\u00fcsseldorf Institute for Synthetic Microbiology 1 Institute for Synthetic Microbiology, HHU D\u00fcsseldorf; 2 CellDEG GmbH Berlin synmikrobiologie.hhu.de CO2 CO2 CO2 NADPH Valencene A WP1: Engineering the bacterial metabolism We previously showed that increasing metabolic flux through the terpenoid biosynthesis pathway had positive effects on strain productivity. Since sesquiterpene production competes with pigment biosynthesis, it is important to supply the cell with sufficient precursor molecules, as well as cofactors. We were able to achieve, rerouting carbon supply from pigment biosynthesis towards product formation with inducible systems1. We aim to build a stable production strain without costly inducers using the following strategies. Titration of expression strength by testing multiple genetic cassettes Testing different sesquiterpene synthases Variation of cultivation conditions Reinforcement of carbon and cofactor supply by rerouting the metabolism (Fig. 1) WP3: Scaling up with CellDEG One main challenge when scaling up the cultivation volume of cyanobacterial strains is ensuring a sufficient availability of nutrients such as light and CO2. The CellDEG technology is specifically designed to enable fast growth of photoautotrophic organisms to a high cell density (Fig. 2B). To identify strains that perform best in such reactors, promising strains will be screened in HD10 reactors early on. Upscaling of the best production strains will take place in the HD1500 production platform (Fig. 2A). The final aim of this project is to achieve a strain with a growth rate of 2.5 g DCW/L/day while maintaining a production rate of 200 mg valencene / g DCW. WP2: Alternative extraction methods Valencene, along with many sesqui- and monoterpenes, is a volatile compound. This is especially advantageous for downstream processing, as it eliminates the need for expensive and time- consuming extraction from the biomass. The current state-of-the-art for quantification of valencene production makes use of a thin layer of dodecane on top of the culture, which captures the volatile product (Fig. 2C). This is favorable for analysis, as dodecane can be analyzed via GC/MS directly. In terms of cost, scalability and sustainability it is of high interest to find alternative extraction- or capturing methods for valencene. A B C Figure 1: Relevant metabolic pathways in the cyanobacterium Synechocystis sp. PCC 6803. Relevant genes for overexpression or deletion are boxed. Involvement of ATP and NADPH is shown in red and blue, respectively. Figure 2 A. From left to right: HD10, HD100, HD1500 reactor setup. B. Growth curves of Synechocystis sp. PCC 6803 WT in the three different reactors. C. Schematic setup for growth of production strains to high cell densities using the HD10 screening platform (image modified from2 Scientific reports, 10(1), 5932 https://doi.org/10.1038/s41598-020-62681-w) 1 OD\u2087\u2085\u2080 = 0,322 gDW L\u207b\u00b9 \u0001 \u0001 \u0001 \u0001 1Dietsch, Behle et al.: Metabolic engineering of Synechocystis sp. PCC 6803 for the photoproduction of the sesquiterpene valencene. Metab. Eng. Commun. 2021 Aug 13", "label": "poster"}
{"text": "U.S. Environmental Protection Agency Office of Research and Development Building an Adverse Outcome Pathway Framework through HTS Data and Literature Mining Integration Nancy C. Baker1, Nisha S. Sipes2, M. Shane Hutson3, Thomas B. Knudsen2 1Lockheed Martin, RTP, NC, 2U.S. EPA, ORD, National Center for Computational Toxicology, 3Departments of Physics and Biological Sciences, Vanderbilt University, Nashville, TN Footnotes Go Here Footnotes Go Here Footnotes Go Here Footnotes Go Here Footnotes Go Here Footnotes Go Here Footnotes Go Here Footnotes Go Here Footnotes Go Here Footnotes Go Here Footnotes Go Here Overview Literature Data Nancy Baker l baker.nancy@epa.gov l 919-541-2680 Interpreting EPA\u2019s ToxCast in vitro assay data in the context of Adverse Outcome Pathway (AOP) development is a significant challenge. While chemical activation in these assays may shed light on the molecular initiating event, it can be difficult to identify the downstream effect of these activities at higher levels of biological organization (e.g., cellular, tissue, organ) that could potentially lead to a toxicity endpoint. In this research, we explore applications of literature mining techniques that can be readily used to build and evaluate an AOP framework from in vitro data. We use cleft palate as a prototype and focus on the ToxCast assay targets that were found to have a significant univariate association with cleft palate / cleft lip (CLP) in ToxRefDB and the literature. DISCLAIMER: does not reflect EPA policy Proteins Chemicals Effects 51 million annotations 24 million annotations 18 million annotations >22 million articles A connection Analyze the EPA\u2019s ToxCast HTS dataset containing > 1,000 unique chemicals tested across >500 in vitro assays to identify the assays with the most significant univariate association with chemicals that cause cleft palate or cleft lip. Find the literature connections between ToxCast targets and cell-level activity/entities and tissue-level activity and entities. Connections are defined as an article co-annotation between a target protein and the cell/tissue entity. Strategy Target Tissue Level CLP Organ Cell Level Option 1. Binary relationships Option 2. Expand relationships Option 3. Bidirectional relationships Results Target Tissue Level CLP Organ Cell Level ToxCast: 56 chemicals in the ToxCast libraries were identified as CLP actives by reviewing data in ToxRefDB and the biomedical literature. A statistical analysis of the assay data identified 29 assays that correlated significantly with the CLP endpoints. (Student\u2019s T-test (p<=0.05)) A subset of those assays with the corresponding Medical Subject Heading (MeSH) term for the target protein is found in Table 1. These statistical correlations represent potential molecular targets that have been assayed in the ToxCast portfolio and serve as a potential entry point for AOPs leading to a cleft palate/cleft lip phenotype in pregnant rats and/or rabbits. Literature: The search of EPA\u2019s biomedical literature database using the term Cleft Palate retrieved 36 unique tissue MeSH terms, 37 cell types, 34 cellular processes, and 54 non-cellular processes. Co-annotations of these tissue or cell types and any of the MeSH terms for the ToxCast targets (Table 1) were also retrieved. The articles were counted and the results output to the database and extracted (with hyperlinks) into the spreadsheets show below. Observations deduced from the subject categories serve as a starting point to fill in the biological space between the assays and the endpoint based on what is known in the literature. Target Cell Level Tissue Level Tissue Level Tissue Level Tissue Level CLP Organ CLP Organ CLP Organ Organ CLP Organ CLP Organ Organ AOP Framework: Table 1. Selected assays with significant univariate association with cleft lip / cleft palate; Blue: nuclear receptors; Gray: GPCRs; Green: other ToxCast Assay Target - selected MeSH term NVS_ENZ_oCOX1 Cyclooxygenase 1 NVS_ENZ_hElastase Leukoc", "label": "poster"}
{"text": "There is increasing recognition of the scope of cultural change needed to realize the European vision for Open Science policy. Key challenges include contemporary modes of recognition and reward that are out of step with principles of open science[1] and identi@ication of numerous disincentives, at the individual level, regarding adoption of new openness practices[2]. These obstacles raise questions about implementation of top-down policy in general, and the European Commission's open science policy in particular. (mock-up) x-xxxx-xxxx-xxxx Contributor Contributions, Open Scholarship \u2022\u2014\u2014\u2014\u2014\u2014 \u2022\u2014\u2014- \u2022\u2014\u2014\u2014\u2014\u2014 \u2022\u2014\u2014\u2014\u2014 \u2022\u2014\u2014\u2014\u2014\u2014 \u2022\u2014\u2014\u2014\u2014\u2014 Openness Pro\ufb01le (individual) Openness Pro\ufb01le (group) Contributor x-xxxx-xxxx-xxxx Repository, (e.g. Zenodo or RAiD) individual group Research and Innovation \u2013 a vision for Europe Open Innovation Open Science Open to the World In what ways is open science policy informed by the science of science? Although evaluation of open science is gaining traction as an important dimension for implementation of open science policy, there is not yet much in the way of empirical analysis. To address this question, we begin with a targeted search in the Web of Science bibliographic database (WoS), which yields three citation networks associated with: open access, open data, and open science[3]. With a combined total of approximately @ive-thousand publication records, published between 1958 and 2018, we then use VOSviewer for analysis and visualization of keyword terms at an aggregate level. Keyword mapping illustrates the relatedness of research topics on the bases of keyword co-occurrence. \u2014> economics of academic publishing \u2014> transparency and accountability \u2014> a\ufb00ordances of digital media and computa8onal resources \u2014> technical integrity of scien8\ufb01c processes and outputs \u2014> rapid dissemina8on of medically relevant knowledge In our analysis of the combined keyword datasets, the three queried topics largely retain their individual structures with some interlinking across networks. The keyword map also identi@ies sub-networks that reveal motivating factors associated with the broader openness movement, such as: economics of academic publishing, transparency and accountability, affordances of digital media and computational resources, technical integrity of scienti@ic processes and outputs, and rapid dissemination of medically relevant knowledge. While we identify some common ground between the European notion of open science and the keyword networks, the research topics identi@ied shed light on a more complex relationship between research practice and increased openness. In other words, the European notion of open science appears to draw on particular understandings of the sciences system, characterized by close alignment with economic activity and a clear, albeit linear, view of how science bene;its society. Open science is seen as a natural extension of existing research practices. Missing from this vision is attention to research practices that do not align so easily with economic activity and research @ields that hold a more indirect relationship with society. Within the community of policy makers and advocates of open Science, there is increasing consensus that (a) better recognition and reward of openness practices is a necessary condition for broad adoption of open scholarship, (b) top-down guidance, which is aimed at a wide range of disciplinary practices, will require substantial cultural change to shift the priority of research evaluation toward principles of open scholarship and (c) bottom-up openness initiatives and practices must emerge from local contexts to enable relevant, sustainable change [1, 2]. The Knowledge Exchange working group addressing this issue[4], proposes an Openness Pro\ufb01le for making visible and being recognized for one\u2019s contribu?ons to open scholarship. The aim in this endeavor is to provide complementary, boFom-up resources linked to contemporary Research Informa8on infrastructure. There are", "label": "poster"}
{"text": "LA CIENCIA ABIERTA EN LA UNIVERSIDAD DE PUERTO RICO OBJETIVO DE LA INVESTIGACI\u00d3N Explorar la apertura y el intercambio de los procesos, herramientas y resultados de investigaci\u00f3n en la Universidad de Puerto Rico (UPR), en cuatro dimensiones de la Ciencia Abierta: (I) Acceso abierto (Open Access) (II) Revisi\u00f3n por pares abierta (Open Peer review) (III) Recursos educativos abiertos (Open Educational Resources) (IV) C\u00f3digo Abierto (Open Source) METODOLOG\u00cdA \u2022 Estudio inicial de car\u00e1cter exploratorio y fundamentalmente descriptivo \u2022 Fuentes para la recogida de la informaci\u00f3n: - Pol\u00edtica de Acceso Abierto a los resultados de la labor creativa e investigaciones producidas en la Universidad de Puerto Rico (Certificaci\u00f3n 113, 2019-2020) - Portal de Revistas Acad\u00e9micas de la Universidad de Puerto Rico - Estad\u00edsticas de acceso y uso de los repositorios institucionales de la UPR - Scopus\u00ae (Elsevier's abstract and citation database) CONCLUSIONES Los resultados preliminares de este trabajo reflejan que, indudablemente, el movimiento de la ciencia abierta viene impactando notable en las pol\u00edticas institucionales de la Universidad de Puerto Rico, que en los \u00faltimos a\u00f1os ha puesto en marcha distintas iniciativas para favorecer el proceso de apertura e intercambio de sus resultados de investigaci\u00f3n. RESULTADOS PRELIMINARES: acceso abierto Dra. Cl\u00e1udia De Souza claudia.souza@upr.edu Profesora Catedr\u00e1tica Auxiliar Dr. Carlos A. Su\u00e1rez Balseiro carlos.suarez5@upr.edu Profesor Catedr\u00e1tico Universidad de Puerto Rico, Recinto de R\u00edo Piedras (UPRRP) Facultad de Comunicaci\u00f3n e Informaci\u00f3n (FaCI) https://faci.uprrp.edu/ Programa Graduado en Ciencias de la Informaci\u00f3n 443 436 490 643 592 714 902 906 969 986 1070 974 1001 944 1017 1032 1048 1091 1071 1010 1084 13,32 60,42 0,00 5,00 10,00 15,00 20,00 25,00 30,00 35,00 40,00 45,00 50,00 55,00 60,00 65,00 70,00 75,00 80,00 85,00 90,00 95,00 100,00 0 100 200 300 400 500 600 700 800 900 1000 1100 N. docs UPR % All Open Access 28 revistas editadas o coeditadas en 5 recintos de la UPR M\u00e1s de 9000 documentos disponibles a texto completo", "label": "poster"}
{"text": "Summarized findings \uf076Two candidate effectors, PM02_g378 and PM02_g2610, localize to the cell periphery while the remaining putative effectors localize to both the nucleus and cell periphery \uf076PM02_g1115, PM02_g7882 and PM02_g8240 consistently suppress chitin-dependent ROS production when transiently expressed in N. benthamiana \uf076PM02_g1115 suppresses Pseudomonas syringae DC3000-mediated cell death in maize \\ Acknowledgments and Funding We thank Dr. Tesfaye Mengiste (Purdue University) for access to the microplate reader for ROS suppression assays, Dr. Rachel Hiles and Dr. Terri Cameron for their technical assistance, and the Purdue University Imaging Facility for access to the Zeiss LSM880 Axio Examiner upright confocal microscope. This research was funded by the USDA-ARS research project 5020-21220-014-00D. USDA is an equal opportunity provider and employer. Candidate effector proteins from from the maize tar spot pathogen Phyllachora maydis suppress immune responses Abigail Rogers1\u2020,Namrata Jaiswal2 \u2020, Emily Roggenkamp3, Hye-Seon Kim4, Joshua S. MacCready3, Martin Chilvers3, Steven R. Scofield2, Anjali Iyer-Pascuzzi1, and Matthew Helm2 * \u2020 these authors contributed equally to this work 1 Department of Botany and Plant Pathology, Purdue University West Lafayette, IN 47907, U.S.A. 2 Crop Production and Pest Control Research Unit, U.S. Department of Agriculture-Agricultural Research Service (USDA-ARS), West Lafayette, IN 47907, U.S.A., 3 Department of Plant, Soil, and Microbial Sciences, Michigan State University, East Lansing, MI, 48824 4 Mycotoxin Prevention and Applied Microbiology Research Unit, USDA-ARS, Peoria, IL, U.S.A. * Corresponding author: M. Helm; Email: Matthew.Helm@usda.gov Significance @LabAbbie27 To better understand the molecular mechanisms underlying the P. maydis \u2013 maize interaction, we investigated how P. maydis utilizes effectors to induce disease. Leveraging the most recent genome annotation, we identified eighteen candidate virulence (effector) proteins that are expressed during disease development and assessed whether these putative effectors suppress immune responses using heterologous expression systems, including Nicotiana benthamiana and the bacterial type III secretion system from Pseudomonas syringae DC3000. Three P. maydis effector candidates suppress chitin-mediated ROS production in N. benthamiana Figure 5. Protein structures were predicted with ColabFold v1.5.2: AlphaFold2 and visualized using the ChimeraX-1.5 modeler package. Here we present the predicted structures of three PmECs which have cell surface-triggered immune suppression activities. The coloring of the models depicts the predicted local distance different test (pLDDT) which indicates the per-residue confidence score. Higher confidence scores are depicted in cool colors while low confidence scores are depicted in warmer colors. Figure 2. Transient expression assays were performed at 48 hours post infiltration. The sub-cellular localizations of PmEC-sYFP fusions were determined by laser scanning confocal microscopy (A). Expression of full-length PmEC-sYFP fusions in N. benthamiana leaves was confirmed by western blot analysis (B). Figure 3. Transient expression of candidate effector- fluorescent protein fusions suppress reactive oxygen species (ROS) burst triggered by chitin in N. benthamiana. The indicated constructs were expressed in N. benthamiana. Forty-eight hours post-agroinfiltration, N. benthamiana leaf disks were collected, challenged with chitin, and relative luminescence was monitored for 40 minutes using a luminol-based assay. Free sYFP (3xHA:sYFP) was used as a reference control P. maydis effector candidates localize primarily to the nucleus and cell periphery Predicted protein structures of the candidate effectors as determined by AlphaFold2 An introduction to Phyllachora maydis The fungal phytopathogen Phyllachora maydis is an obligate pathogen of maize and is the causal agent of tar spot disease. It was first identifie", "label": "poster"}
{"text": "1. Inhibition and processing speed impaired in MCI and AD groups \u2022 Standardised tests detect cognitive changes in impaired groups, and more so in inhibition than processing speed 2. WM fibre density (FD) in SLF differed between groups, but not FC, and little for FDC \u2022 Density, rather than volume of the fibre, steadily decreased between groups \u2022 While C and SCD groups had similar cognitive performance, the SLF FD differed. The C group had greater SLF FD, while the SCD group\u2019s SLF FD was more similar to the MCI and AD groups 3. Inhibition, and not processing speed significantly correlated with FD in the left SLF 2 and 3 \u2022 The SLF plays a critical role in inhibition processes in AD risk cohorts Funding from Brain Research New Zealand (BRNZ) We thank the participants and DPRC staff for giving their time for this study. SCD n = 60 C n = 35 mMCI n = 52 AD n = 27 aMCI n = 55 Lenore T Tahara-Eckl1,2, Reece Roberts1,2, Catherine Morgan1,2, Flavio Dell\u2019Acqua3, Ian Kirk1,2, Tracy R Melzer4,6, John C Dalrymple-Alford4,5, Tim J Anderson4,6, Nicholas J Cutfield7, Lynette Tippett1,2 1School of Psychology, University of Auckland, New Zealand; 2Centre for Brain Research, University of Auckland, New Zealand; 3Forensic and Neurodevelopmental Sciences, King\u2019s College, London, England; 4NZ Brain Research Institute, Christchurch, New Zealand; 5School of Psychology, Speech and Hearing, University of Canterbury, Christchurch, New Zealand; 6Department of Medicine, University of Otago, Christchurch, New Zealand; 7Department of Medicine, University of Otago, Dunedin, New Zealand Participants. n = 229 (122 F, 69.75 \u00b1 8.25 years), recruited from the Dementia Prevention Research Clinic (DPRC) over three sites: Auckland, Christchurch, Dunedin Neuropsychological assessment. Normal Fibre Bundle Reduced FD Reduced FC Reduced FDC Fixel-based analysis (FBA) for FD, FC, and FDC5 1. Rabin, L. A., Smart, C. M., and Amariglio, R. E. 2017. Annual Review of Clinical Psychology, 13(1), 369\u2013396. 2. Lockhart, S. N., & DeCarli, C. 2014. Neuropsychology Review, 24(3), 271\u2013289. 3. Perry, R. J., & Hodges, J. R. 1999. Brain, 122(3), 383\u2013404. 4. Bennett, I. J., & Madden, D. J. 2014. Neuroscience, 12(276), 187\u2013205. 5. Sasson, E., Doniger, G. M., Pasternak, O., Tarrasch, R., and Assaf, Y. 2013. Frontiers in Neuroscience, 7(7 MAR), 1\u201313. 6. Cremers, L. G. M., de Groot, M., Hofman, A., Krestin, G. P., van der Lugt, A., Niessen, W. J., Vernooij, M. W., and Ikram, M. A. 2016. Neurobiology of Aging, 39, 108\u2013117. 7. Raffelt, D. A., Tournier, J. D., Smith, R. E., Vaughan, D. N., Jackson, G., Ridgway, G. R., and Connelly, A. 2017. NeuroImage, 144, 58\u201373. 8. Tournier, J. D., Smith, R., Raffelt, D., Tabbara, R., Dhollander, T., Pietsch, M., Christiaens, D., Jeurissen, B., Yeh, C. H., and Connelly, A. 2019. NeuroImage, 202(August), 116137. Five participant groups (total n = 229) Poorer executive function is associated with lower white matter fibre density in the superior longitudinal fasciculus in groups at risk of Alzheimer\u2019s disease Diffusion FOD Image acquisition and preprocessing. Diffusion-weighted MRI (100 directions, b = 1000, 2000 s/mm2). FOD estimation with multi-tissue constrained spherical deconvolution and FBA processed with MRtrix38 Six SLF tracts of interest. Left: SLF tracts coloured by direction (red = right-left, blue = superior-inferior, green = anterior- posterior). Right: SLF tracts segmented by number (SLF1, SLF2, SLF3) In groups at different levels of risk of AD\u2026 1. Do measures of processing speed and inhibition differ? 2. Do SLF fibre properties differ? 3. Do the SLF tracts correlate with processing speed and inhibition measures? Research Questions Background Methods Processing Speed Hayling\u2019s Congruent Sentence Set 1 Stroop Colour Naming Stroop Word Reading Trail Making Test A Inhibition Hayling\u2019s Incongruent Sentence Set 2 Hayling Category A Error Hayling Category B Error Stroop Inhibition Category Switching Trail Making Test B Our findings suggest that specific mi", "label": "poster"}
{"text": "Commissariat \u00e0 l\u2019\u00e9nergie atomique et aux \u00e9nergies alternatives INES | 50 avenue du lac L\u00e9man | 73375 Le Bourget-du-Lac www-liten.cea.fr / www.ines-solaire.org DEVELOPMENT AND IMPROVEMENT OF METHODS FOR REDUCING CONTAMINATION OF SILICON-KERF FROM WAFER SLICING Roland RIVA, Margot LANDA-PLIQUET, Fabrice COUSTIER UNIVERSIT\u00c9 GRENOBLE ALPES, CEA, LITEN, CAMPUS INES, 73375 LE BOURGET DU LAC, FRANCE CONTACT : Roland RIVA, roland.riva@cea.fr This project has received funding from the European Union\u2019s Horizon 2020 research and innovation program under grant agreement No 958365 CONTEXT \uf07e35% silicon-kerf loss during wafer slicing (diamond wire) \uf0derecycling desirable Silicon contamination from cutting liquid (water + additives), brick holder (beam) and diamond wire CONTAMINATION REDUCTION OF SILICON-KERF 1) DURING WAFER SLICING \uf0d8Low concentration (Carbon Oxygen Demand) coolant \uf0dedecrease of carbon \uf0d8Beam composition (silicon-based filler) \uf0dealuminum reduction 2) ON DRY RECOVERED SILICON-KERF \uf0d8Soft chemical treatment (HCl) followed by thermal treatment (2 hours @ 500\u00b0C) \uf0deMain residual contaminant = nickel (from cutting wire coating) CONCLUSION \u2022 Raw silicon-kerf purity can be enhanced to 3N (99.9%, excluding light elements) without industrial cutting process modification thanks to cutting liquid and beam composition change \u2022 Additional soft chemical treatment, followed by thermal treatment can drastically reduce carbon concentration and increase silicon-kerf purity to 4N (99.99%) References \u2022 H. Hajjaji, F. Coustier, V. Briz\u00e9, A. Benayad, M. Benmansour, A. Chabli, \u201cRecycling of Kerf-Loss Silicon Powder from Diamond-Wire Cutting Without Chemical Treatment\u201d, EU PVSEC 33, 2017. \u2022 M. Vazquez-Pufleau, T.S. Chadha, G. Yablonsky, P. Biswas, \u201c Carbon elimination from silicon kerf: Thermogravimetric analysis and mechanistic considerations\u201d, Scientific Reports, Volume 7, 2017. \u2022 F. Coustier, V. Briz\u00e9, H. Hajjaji, \u201cWire cutting support for bonded abrasives comprising an assembly of different materials, system comprising such a support and wire cutting methods\u201d, European Patent EP 3 424 663 A1, 2017. \u2022 X. Li, G. Lv, W. Ma, T. Li, R. Zhang, J. Zhang, S. Li, Y. Lei, \u201cReview of resource and recycling of silicon powder from diamond-wire sawing silicon waste\u201d, Journal of Hazardous Materials, Volume 424, Part A, 2022. \u2022 Z. Hu, G. Wang, J. Li, Y. Tan, Y. liu, P. Li, \u201cRecycling of diamond-wire sawing silicon powder by direct current assisted directional solidification\u201d, Waste Management, Volume 157, 2023. \uf0deMetals divided by 3 and carbon by 6 from raw Si-kerf 1BV.5.5", "label": "poster"}
{"text": "Hochschule f\u00fcr Gesundheit \u00b7 University of Applied Sciences \u00b7 Gesundheitscampus 8 \u00b7 44801 Bochum Raising awareness for RDM: The importance of multipliers within the institution anke.osterhoff@hs-gesundheit.de Osterhoff, Anke & Koch, Katharina Hochschule f\u00fcr Gesundheit, Bochum, Germany State of RDM at UAS Professional research data management (RDM) is becoming increasingly important not only at universities but also at universities of applied sciences (UAS). This is partly due to DFG and other authorities\u2019 regulations regarding RDM, which means that more and more third-party funding bodies require RDM for funding. Additionally, research at UAS is often practical and application-oriented, which means that the findings and results can quickly flow into different areas of society, the economy, and culture to create innovation and transformation. Research data at UAS therefore has yet rather underutilized scientific, cultural, and economic potential, especially in terms of its subsequent applied use. Professional RDM is essential for realizing these opportunities. Researchers and institutions are becoming increasingly sensitive to its potential. Yet, UAS are burdened with high teaching loads and relatively little funds for research, while RDM is often not funded at all. Starting points Bringing RDM into practice at the institutional level and raising awareness among researchers, administrative and infrastructural stakeholders is challenging. Thus, we placed special focus on the role of voluntary multipliers within the institution. These voluntary multipliers are also referred to as \u201cdata champions\u201d [1] and can be considered key actors for raising awareness for RDM among researchers as their peers and can serve to complement the work of professional RDM staff (such as data stewards). In our example, RDM as a concept was initially introduced by the Research and Transfer Office with the support of university leadership, which recognized RDM as strategically important. The initial situation was as follows: \u2022 no professional RDM staff \u2022 all efforts to establish RDM took place on a voluntary basis \u2022 consultation with RDM-initiatives \u2022 contacting associated working groups for guidance Strategies for increased institutional RDM awareness Our first goal was to create a trickle-down effect by making RDM a topic of discussion in several institutional committees, starting with UAS leadership. This includes regular reporting about RDM and linking RDM with other current topics, e.g. the institution's digitization strategy or establishing a local repository. Furthermore, specific measures have been initiated to establish services related to RDM, e.g. by acquiring third-party funding for RDM- related research. Thanks to said funding, a data steward (0,5 FTE) is currently developing subject-specific RDM services and providing practical support for researchers. Another important step to make RDM visible in the institution was to appoint a professorial, voluntary RDM representative. Said professor serves as an important multiplier due to their RDM-related expertise and research interests. They can be considered a sort of data champion due to their specific RDM-knowledge [2]. We selected them since they have a comprehensive understanding of the importance of well-planned research data management practice and are passionate about sharing discipline-specific expertise and advancing FAIR principles and good scientific/RDM practice [1]. In doing so, the RDM representative is one of our institution\u2019s key actors in promoting changes in research culture towards RDM and Open Science. They work in close collaboration with the Research and Transfer Office and data steward. Additionally, their feedback and assessment have been crucial to improving our RDM services. As a long-standing professor, they are experienced, trusted, and well known at the institution. The role benefits greatly from selecting a low-threshold contact person for academic peers to ask about R", "label": "poster"}
{"text": "Barriers & Enablers of Intercropping and Enhanced Crop Diversification in the UK Trivett E.E\u00b9 Bates L\u00b9 Drummond C.J\u00b9 \u00b9 LEAF (Linking Environment And Farming) CV8 2LG, UK ABSTRACT Increasingly volatile weather conditions and extreme weather events have increased challenges in pest management in single variety cropping. A need to enhance Integrated Pest Management (IPM) has led to the use of plant species mixtures or \u2018plant teams\u2019 to optimise performance, improve yield stability, reduce pest and disease damage and enhance stress resilience in agricultural systems. Combined with supporting Integrated Farm Management (IFM) practices, intercropping, in field crop mixtures and other examples of enhanced crop diversification have gained attention in recent years due to the beneficial effects of soil fertility, nutrient recycling and pest, weed and disease management. However, uptake remains limited in the UK. Barriers to and opportunities presented by enhanced crop diversification are illustrated through a series of case studies from across three projects LEAF collaborated on between 2017 and 2020. Enablers and barriers to adoption of enhanced crop diversification are illustrated, concluding that a range of approaches will be necessary to support upscaling of these practices in the UK. We are grateful to of received the support and funding from the following projects to make this study possible. The project DiverIMPACTS - \"Diversification through Rotation, Intercropping, Multiple Cropping, Promoted with Actors and value-Chains towards Sustainability\" is supported by the European Union's HORIZON 2020 research and innovation programme under Grant Agreement no 727482 and by the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number 17.00092. The DIVERSify project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under agreement No. 727284. The SEAMS project Funded by the Esm\u00e9e Fairbairn Foundation, and coordinated by the James Hutton Institute. Enablers Barriers \u2022 Soil health and fertility \u2022 Integrated Pest Management \u2022 Mixed farming systems lend themselves well to enhanced crop diversification \u2022 Investment and availability of machinery \u2022 Seed separation \u2022 Establishment \u2022 Lack of knowledge exchange Outcomes Through H2020 projects DIVERSify , DiverIMPACTS and Esmee Fairbairn Foundation project SEAMS, LEAF has been working with a range of UK farmers and stakeholders since 2017 on enhanced crop diversification projects. A farmer engagement workshop \u2018Experiences, barriers and opportunities in plant teams\u2019 was carried out at West Gilson Mains, Fife as part of the SEAMS project. The outcome of this event was a summary of plenary discussions between farmers, agronomists and industry representatives. Two farmer led case studies were delivered as part of LEAF\u2019s contribution to the H2020 project cluster \u2018Crop Diversification\u2019 which includes the DIVERSify and DiverIMPACTS projects. Enablers of barriers to the uptake of enhanced crop diversification approaches such as intercropping , companion cropping and rotation extension were the focus of all three outputs. Enablers were classified as site specific farm business approaches which improved access, incentive or motivation to employ enhanced crop diversification strategies. Barriers were categorised as unresolved challenges or perceived risks in the adoption of such approaches. Companion, cover and intercropping and extended rotations all have potential to enhance sustainability in UK cropping. An increase in effective knowledge exchange to highlight opportunities, and advice and support to help overcome barriers will be required. Where the balance between risks against benefits is seen to pay off, an increase in the adoption of enhanced crop diversification is more likely. Farming 300ha\u2019s of arable ground, intercropping trials have been a particular interest in the farms diverse 9 crop wide rotation. Seed separation i", "label": "poster"}
{"text": "Diameters Star Sp Type (mas) 1 Diameter ( )2 NR Vul K3 I (L05) 3.04 0.1 4.12 BD+354077 M2.5 I (L05) 3.18 0.13 5.45 BI Cyg M3-M4 I (L05) 5.16 0.34 9.21 RW Cyg M3 I (L05) 5.09 0.36 11.8 AZ Cyg M3 Iab (M19) 3.74 0.18 8.41 V424 Lac M0 I (L05) 3.77 0.08 12.6 V 336 And M2Ib (KM89) 2.46 0.05 3.08 AD Per M2.5 Iab (M19) 2.39 0.15 8.39 BU Per M3 I (L05) 2.27 0.29 21.0 FZ Per M1.5 (M19) 1.8 0.24 13.7 KK Per M2 Iab-Ib (M19) 2.27 0.10 2.17 SU Per M3-M4 I (L 05) 3.20 0.21 10.9 RS Per M4 I (L 05) 2.96 0.13 5.13 S Per M4.5 I (L 05) 4.08 0.36 6.91 W Per M4.5 I (L05) 2.93 0.12 6.14 XX Per M4 Ib (M19) 2.77 0.16 5.90 6 Gem M1-M2 Ia-Iab (KM89) 4.11 0.48 49.3 TV Gem M1 I (L 05) 3.41 0.53 37.5 WY Gem M2 Iabep+ (M19) 2.68 0.03 3.96 An Interferometric Imaging Survey of Red Supergiant Stars Ryan P. Norris (New Mexico Tech) Abstract Red supergiant stars (RSGs) are an end stage of massive star evolution. Among the notable behaviors of stars during this stage are their irregular and semi- regular variability and mass-loss. In order to better understand the sources of these phenomena, we collected high resolution optical interferometric observations of 17 RSGs using the Center for High Angular Resolution Astronomy (CHARA) Array at Mount Wilson between 2015 and 2016. Here, we present stellar diameters derived from these data. We comment on evidence of surface asymmetries on those stars for which we were able to obtain closure phases and present an example image for one of these objects. In addition, we have obtained near-contemporaneous spectroscopy of these stars using SpeX on the NASA InfraRed Telescope Facility (IRTF). We have developed libraries of synthetic spectra derived from spherical MARCS, PHOENIX, and SATLAS stellar atmospheres, and are currently working to derive fundamental stellar parameters with these data. Diameter Fitting We used the OITOOLS.jl1 package to run a grid search for fitting model limb-darkened disks to the squared visibilities. Future efforts will resistrict the fit to the first two lobes of the visibility curve in order to avoid effects from large surface features. 1:https://github.com/fabienbaron/OITOOLS.jl Figure 1: Example \u03c72 surface for the linearally limb-darkened disk of RS Per. 1: Linear limb-darkening coefficent. 2: Using Gaia parallaxes as reported in Bailer-Jones et al. 2018 References 1)Bailer-Jones, C. A. L., Rybizki, J., Fouesneau, M.,Mantelet, G., & Andrae, R. 2018, AJ, 156, 58 2)Keenan P. C., McNeil R. C., 1989,ApJS, 71, 245 (KM89) 3)Levesque, E. M., Massey, P., Olsen, K. A. G., et al. 2005,ApJ,628, 973 (L05) 4) Norris et al. 2021. Submitted.. 5)Messineo, M., & Brown, A. G. A. 2019,AJ,158, 20 (M19) Example Imaging Image Reconstruction Of the 17 stars observed 10 have enough (u, v) coverage for image reconstruction and have closure phases suggesting surface assymetries. In Figure 2, we present an example image for RS Per. Details of the reconstruction process can be found in Norris et al. 2021. We used SQUEEZE1 and the OITOOLS.jl package to reconstruct images. 1:https://github.com/fabienbaron/squeeze Figure 2: Image reconstruction of RS Per (top) and corresponding uv coverage (bottom). Beam size is depicted in the lower right corner of the image. Image was reconstructed using SQUEEZE and total variation and Laplacian regularizers.", "label": "poster"}
{"text": "using the QR-Code and: your training. gaps or needs for further training and your training. Get your training if you meet at least 80% of the principles recommended by the research community. your badged training to the OS Learning Gate. reach out: buchheit@paedagogik.uni-kiel.de alavi@zke-kiel.de Help us to create an intersection of high-quality and reliable OS training in line with principles of Research Integrity, Research Ethics and Ethics of AI operating with OS tailored according to the needs of various OS learning groups. Join us in the OPEN SCIENCE LEARNING GATE 3 2 1 4 SCREEN IDENTIFY & COMMUNICATE BADGED CONNECT AMEND QUESTIONNAIRE Starting at the beginning of June 2024 ENTER NERQ_OS QUESTIONNAIRE for Julia Priess-Buchheit, Joeri K. Tijdink, Katharina Miller, Sean Lacey, Peter Eduard, Marie Alavi (and more from NERQ_OS Group)Julia Priess-Buchheit, Joeri K. Tijdink, Katharina Miller, Sean Lacey, Peter Eduard, Marie Alavi (and more from NERQ_OS Group) OPEN SCIENCE Learning Gate tailored capacity building for OS training Authors: Julia Priess-Buchheit, Marie Alavi With contribution of: Joeri K. Tijdink, Katharina Miller, Ruth Moran, Varga Orsolya, Maruxa Martinez, Ulf T\u00f6lch, Sean Lacey , Peter Eduard, Anita Luni\u0107 (and more from NERQ_OS Group)With contribution of: Joeri K. Tijdink, Katharina Miller, Ruth Moran, Varga Orsolya, Maruxa Martinez, Ulf T\u00f6lch, Sean Lacey, Peter Eduard, Anita Luni\u0107 (and more from NERQ_OS Group) SIG_OS", "label": "poster"}
{"text": "A Model for Interpretable High Dimensional Interactions Bhatnagar SR1,2, Yang Y3, Blanchette M4, Greenwood CMT1,2 1Department of Epidemiology, Biostatistics and Occupational Health, McGill University 2Lady Davis Institute, Jewish General Hospital, Montreal, QC 3Department of Mathematics and Statistics, McGill University, QC 4School of Computer Science, McGill University Summary \u2022 Environmental exposures may induce subtle system-wide changes in high- dimensional genomic data such as gene expression or epigenetic measures \u2013 Can such situations be exploited to improve prediction models? \u2022 Large system-wide changes are observed in many environments and hence this assumption can possibly be exploited to aid analysis of high dimensional data \u2022 We develop and implement a multivariate penalization procedure for predict- ing a continuous or binary disease outcome while detecting interactions between high dimensional data (p >> n) and an environmental factor. R software: http://sahirbhatnagar.com/eclust/ \u2013 Dimension reduction is achieved through leveraging the environmental-class- conditional correlations \u2013 Also, we develop and implement a strong heredity framework within the penal- ized model Motivation Figure 1: Microarray study of COPD. Top: Heatmap of Pearson correlations. Bottom: Heatmap of gene expression data (2,900 genes) rows are genes and columns are subjects. There are 7 subjects in each group, matched on COPD case status, gender and age. Methods Figure 3: Method overview. First step involves measuring gene similarity in both exposure groups. We then cluster these and create a cluster representation. The last step involves entering these terms in a penalization model that follows the strong heredity principle [1] Figure 4: Clustering based on Fisher\u2019s Z transformation of exposure dependent correla- tions. Let \u03c1ijk be the correlation between genes i and j in class k. Transform the corre- lations into z values: zijk = 0.5log|(1 + \u03c1ijk)/(1 \u2212\u03c1ijk)|. The Z-test statistic is given by |zij0 \u2212zij1|/ p 1/(n0 \u22123) + 1/(n1 \u22123) \u223cN(0, 1) \u2022 Model: g(\u00b5) = \u03b20 + \u03b21X1 + \u00b7 \u00b7 \u00b7 + \u03b2pXp + \u03b2EE | {z } main e\ufb00ects + \u03b11E(X1E) + \u00b7 \u00b7 \u00b7 + \u03b1pE(XpE) | {z } interactions \u2022 Strong Hierarchy Principle [1]: \u02c6\u03b1jE \u0338= 0 \u21d2 \u02c6\u03b2j \u0338= 0 and \u02c6\u03b2E \u0338= 0 \u2022 Reparametrization [2]: \u03b1jE = \u03b3jE\u03b2j\u03b2E. \u2022 Variable Selection: arg min\u03b20,\u03b2,\u03b3 1 2 \u2225Y \u2212g(\u00b5)\u22252 + \u03bb\u03b2 \u0000w1\u03b21 + \u00b7 \u00b7 \u00b7 + wq\u03b2q + wE\u03b2E \u0001 + \u03bb\u03b3 \u0000w1E\u03b31E + \u00b7 \u00b7 \u00b7 + wqE\u03b3qE \u0001 \u2022 Adaptive weights: wj = 1 \u02c6\u03b2j , wjE = \u02c6\u03b2j \u02c6\u03b2E \u02c6\u03b1jE \u2022 Why strong heredity? \u2013 Statistical Power: large main e\ufb00ects are more likely to lead to detectable interactions than small ones \u2013 Interpretability: Assuming a model with interaction only is generally not biologically plausible \u2013 Practical Sparsity: X1, E, X1 \u00b7 E (2 variables to measure) vs. X1, E, X2 \u00b7 E (3 variables to measure). Simulation Study Results Figure 5: Stability of results: Average Jaccard distance from 10-fold cross validation. A Jaccard distance of 1 indicates perfect agreement between two sets while no agreement will result in a distance of 0. Figure 6: Prediction accuracy: Test set mean squared error This work was supported by the Ludmer Centre for Neuroinformatics and Mental Health. Software available at http://sahirbhatnagar.com/eclust/. References [1] Hugh Chipman. Bayesian variable selection with related predictors. Canadian Journal of Statis- tics, 24(1):17\u201336, 1996. [2] Nam Hee Choi, William Li, and Ji Zhu. Variable selection with the strong heredity constraint and its oracle property. Journal of the American Statistical Association, 105(489):354\u2013364, 2010.", "label": "poster"}
{"text": "INCIPIT-CSIC Monte Gaias s/n, Edificio Font\u00e1n, bloque 4, 15707, Santiago de Compostela, Galicia, Spain leticia.tobalina-pulido@incipit.csic.es A thorough recording and collection of archaeological finds allows the detection of errors in the field and later on. FROM FIELD TO GIS Intensive archaeological pedestrian survey in the characterisation of Roman rural settlements BIBLIOGRAF\u00cdA Leticia TOBALINA-PULIDO (Institute of Heritage Sciences, CSIC) The use of archaeological survey for the characterisation of Roman sites and their surroundings is not a new topic. We present here the theoretical proposal that we have carried out in recent months, emphasising an exhaustive record that allows us to assess the quality of the archaeological survey. SURVEY APPROACH It is also significant that some imported materials were found, such as a fragment of an amphora made of paste from the Lower Guadalquivir. It is curious that neither Terra Sigillata nor other fine pottery is recorded. Many loom weights were recovered too. Only common pottery and dolia were recorded. The concentration of material, moreover, shows the three concentration patches, possibly corresponding to those indicated in the literature as three archaeological sites. The distribution of archaeological material extends over almost 2ha, making it a settlement of significant size. Considering the classification of L.G. P\u00e9rez-Aguilar (2018) for the southwest of Spain, we can consider that we are dealing with a large farm-type site. Perhaps, in the event that future interventions extend the area of distribution of materials, we may be looking at a small settlement. There is very limited datable artefacts, although a fragment of a highly eroded amphora dates to the 1st century AD. The use of intensive archaeological prospection with the systematic collection of archaeological material has allowed us to characterise archaeological sites from the Roman period of lesser importance and with a complicated materiality (a lot of constructive material and little datable material). PERSPECTIVES CONTACT @dynatinc @dynatinc Firstly, we opted for an intensive archaeological survey with a spacing between surveyors of 5 metres. The intensity changes depending on the terrain. In our case, the two types of land we prospect are pasture and vineyard. In cases of poor visibility in dehesa, we choose to reduce the intensity to 3 metres. Secondly, all archaeological finds are geo-referenced in the field. In addition, all non-constructive archaeological material is collected (also from other chronologies), with the aim of being able to detect identification errors in the field due to poor visibility, for example. In the case of doubts or significant constructive material, it is also collected. Thridly, for each surveyed plot, each prospector has to fill in a sheet indicating issues such as GPS used, visibility, GPS error or field experience. Each of these factors must be indicated on the sheet with a number according to the criteria specified in the sheet's instructions. This allows for a better homogenisation of the data afterwards. APPLICATION EXAMPLE The sheet allows us to know which areas each prospector has surveyed, the previous experience he/she has in the field and the characteristics of the area he/she surveyed. A case study of an application in the municipality of Fronteira, Portugal, is presented here. It is an area previously extensively surveyed and recorded on the archaeological chart as 3 settlements. In addition, one of the problems archaeologists encountered when prospecting it was the difficulty of characterising it. The aim was to characterise the area and determine whether there are three areas of the same site or three separate sites and to characterise it LOCATION OF THE SURVEYED AREA SURVEYED AREA DISPERSION OF ARCHAEOLOGICAL FINDS During the survey we located a large amount of laterite building material. There was also a significant concentration of scoria and dolia. The collecti", "label": "poster"}
{"text": "In order to assess the relationship between \ufb02owering time control and roots, \ufb02owering time mutants and mu- tants isolated from the reverse genetic approach presented above were characterized for root architecture (\ufb01g. 3a). Unexpectedly, we observed that the late \ufb02owering constans (co) mutant had a striking root phenotype (\ufb01g. 3b) although we did not detect expression of the CO gene in the root (data not shown). By contrast, the svp mutant did not display any root phenotype albeit the gene was highly expressed throughout the roots (\ufb01g. 2c). The dormancy asso- ciated2 mutant had a signi\ufb01cant phenotype, including longer primary and secondary roots and an increased lateral root density. The same observations stand for the ipt3;5;7 triple mutant but not for the ipt3 single mutant. Because many \ufb02owering time genes were found to be expressed in the roots, we analyzed the changes in gene expression occurring in the roots during the induction of \ufb02owering. To do so, 7-week old vegetative plants grown in short days (SD) were induced to \ufb02ower by exposure to a single 22-h long day (LD). Roots were harvested during the photoperiod extension for transcriptomic analysis. We found that hundreds of genes were di\ufb00erentially expressed in the roots in LD vs SD (\ufb01g. 2a). The biological signi\ufb01cance of these changes was addressed by recording whether loss of function mutants had a \ufb02owering phenotype. Interestingly the cytokinin-biosynthesis genes IPT3, 5 & 7 (IPT; ISOPENTENYL TRANSFERASE) were all up-regulated in the roots during the during the induction of \ufb02owering (\ufb01g. 2b). According to the root map published by Brady et al. (2007), the expression of IPT3 and IPT5 is restricted to some tissues of the roots (\ufb01g. 2c). We also looked at the expression pattern of well-characterized \ufb02owering time genes detected in roots (\ufb01g. 1b,c). Among them, we ob- served that SHORT VEGETATIVE PHASE (SVP) is expressed throughout the roots (\ufb01g. 2c). FLORAL INDUCTION IMPACTS THE ROOT TRANSCRIPTOME FLOWERING TIME GENES ARE EXPRESSED IN ROOTS Plant Physiology ULg FLOWERING GOES UNDERGROUND F. Bouch\u00e9, G. Lobet, M. D\u2019Aloia, N. Detry, P. Tocquin, C. P\u00e9rilleux. Laboratory of Plant Physiology, University of Li\u00e8ge, B22, Sart Tilman, B-4000 Li\u00e8ge, Belgium Corresponding author: f.bouche@ulg.ac.be In conclusion, complementary approaches based on published expression data, transcriptomic experiments and genetic analyses indicate that genes involved in \ufb02owering time control are expressed in the roots and/or a\ufb00ect root architecture. Further experiments are on the way to downregulate \ufb02owering time genes in the roots by overexpressing arti\ufb01cial microRNAs in an organ-targeted manner. Acknowledgements : FB is grateful to the F.R.S.-FNRS for the award of a PhD fellowship. We thank Pr. Tatsuo Kakimoto (Osaka University, Japan) who kindly provided us with ipt3 and ipt3;5;7 seeds. This research is funded by the Interuniversity Attraction Poles Programme P7/29 initiated by the Belgian Science Policy O\ufb03ce. The genetic control of \ufb02owering is complex : deepest knowledge has been accumulated on Arabidopsis where we identi\ufb01ed 278 \ufb02owering time genes from a littera- ture survey. We then crossed the list with transcriptomic data obtained from roots and found that 98 \ufb02owering time genes were expressed in the roots of Arabidopsis plants grown in hydroponics, on soil, or in vitro (\ufb01g. 1a,b). Among them, genes involved in photoperiodism or light perception were well represented whereas others \u2013 e.g. genes involved in \ufb02ower development - were not (\ufb01g. 1c). References : Brady, S.M. et al., 2007. A high-resolution root spatiotemporal map reveals dominant expression patterns. Science, 318 ( 5851), 801-6. Lobet, G. et al., 2011. Novel Image Analysis Toolbox Enabling Quantitative Analysis of Root System Architecture. Plant Physiology,157, 29-39. AT5G18840 Figure 1. Genes controlling \ufb02owering time in Arabidopsis are expressed in the roots. (a) Root transcriptomic data were obtained from plants grown in hydropo", "label": "poster"}
{"text": "PhD Library Course Topics I\u00b4m a virtual librarian, ready to assist you with your PhD Library Course questions! Available 24/7 to assist PhD candidates with their coursework and research. Provides personalized feedback and real-time support. Helps students brainstorm keywords and formulate effective search queries. Guides users through citation styles and reference management using tools like Zotero. Facilitates understanding and implementation of Open Science practices. Enhances the overall research and learning experience for PhD candidates. Promotes engagement and active learning through interactive assistance. Demonstrates the potential of AI in transforming academic support services. 0% 10% 20% 30% 40% 50% I don't have access to full version of ChatGPT Consult dates and conditions of course Consult for deeper understanding of subject I don't like vi\u0336tual assistance Consult the assignments Archie Bookworm: Virtual Librarian for Advancing PhD Education PhD Library Course in Nutshell Blended learning format combining webinars, in-person workshops, e-learning, and practical assignments. Provides a platform for networking among PhD from different fields (over 90 participants attended this year). Focuses on developing core research competencies and practical skills. Encourages interdisciplinary collaboration and knowledge sharing. Regular feedback and personalized guidance enhance the learning experience (real-time support from the AI virtual librarian). Meet Archie Bookworm Feedback Highlights: How Archie Transformed Learning \u201cArchie helped me formulate effective search queries, making my research process much smoother and more efficient.\u201d \u201cI found the use of AI in teaching through Archie inspiring. I'll be incorporating similar AI tools in my own teaching methods.\" \u201cI'm not a fan of virtual assistants; I prefer human interaction. However, I can see the potential benefits for those who like using AI\u201d Tereza \u0160\u00edmov\u00e1 Czech University of Life Sciences Prague www.terezasimova.com, simovat@lib.czu.cz", "label": "poster"}
{"text": "A Mixed-Mode Simulation Framework to Investigate Neuronal Signal Transduction and Sensing at Nanoelectrodes Federico Leva1*, Pierpaolo Palestri2, Luca Selmi1 1Dipartimento di Ingegneria \u2018\u2018Enzo Ferrari\u2019\u2019, Universit\u00e0 di Modena e Reggio Emilia, Modena, Italy 2Polytechnic department of Engineering and Architecture University of Udine, Udine, Italy *Corresponding author: federico.leva@unimore.it Overview Figure 1: Schematic representation of an intracellular (a) and extracellular (b) FET-based nanoelectrode integrated in CMOS technology, interfaced with a neuron and connected to a transimpedance readout circuit. Accurate physics-based numerical models of coupled neuron-sensor-readout CMOS-based systems are useful to: \u2022 design and optimize the sensing device and the readout, \u2022 interpret the measurements, \u2022 derive lumped-element descriptions of the recording systems related to geometrical and physical properties. A semiconductor-TCAD-based mixed-mode modeling environment is suited for such purposes. We exemplify its capabilities by analyzing relevant figures of merit (including SNR) for an active FET-based nanoelectrode envisioned for intra- and extracellular coupling to neurons (Fig. 1). This work has been financially supported by the European Union\u2019s Horizon 2020 project \u201cIN-FET\u201d (Grant Agreement n. 862882) via the IUNET consortium. Methods The modelling framework consists of a FEM TCAD for semiconductors [1], which supports: \u2022 Mixed device-circuit simulations with user-defined physics and lumped-elements via PMI and CMI, respectively [1]. \u2022 Drift-diffusion transport in the intra- and extracellular electrolyte regions, implemented by mimicking anions and cations with electrons and holes, and suitably adjusting the semiconductor properties [2,3,4]. \u2022 Combined DC steady state, transient, AC small signal, and noise analysis. \u2022 Cellular membrane compartment description as (i) lossless insulator in TCAD (with parameters consistent to [5]), or (ii) lumped capacitor in the circuit portion. \u2022 Action potentials (APs) incorporation onto each membrane\u2019s compartment as either: (i) voltage generator (Fig. 2.b), (ii) current generator (Fig. 2.c), or (iii) Hodgkin- Huxley (HH) [5] circuit model (Fig. 2.a), implemented via custom multi-port memristors described by CMIs. The CMIs set the (de)activation state-variables for the non- linear conductances of the K+ and Na+ ion-channels [5]. Results \u2022 Fig. 3 shows that our mixed-mode approach predicts the expected monophasic (a) and biphasic (b) waveforms of lumped-element circuit models (not shown) derived from state-of-art results [6] for intra- and extracellular contact. \u2022 Fig. 4 reports the neuron-to-readout transfer function (TF1) computed with AC small signal analysis. A band-pass behavior is observed for intracellular contact, whereas a derivative behavior for the extracellular case on the frequency range of the AP spectrum. The TF shapes are consistent with the time-domain profiles of Fig. 3. \u2022 Fig. 5 shows that the active FET-sensor SNR2 is not affected by the presence of the readout noise and only slightly affected by the coupling condition with the neuron, overall achieving adequately large values. \u2022 Extended results can be found in [7]. Figure 2: Different equivalent circuits to include the generation of action potentials across the passive neuron membrane: (a) Hodgkin-Huxley model; (b) external voltage boundary; (c) external current boundary. Figure 3: AP waveform comparison for TCAD and full L.E. Circuit descriptions of an active nanoelectrode in (a) intracellular and (b) extracellular contact (Fig. 1). Vm is the intracellular neuron signal, Vout is the output signal of the readout. Figure 4: Modulus of the system transfer function of the active intracellular and extracellular sensing systems (Fig. 1). Figure 5: SNR for the different access types, and in presence or absence of the readout noise. The readout gain has been set to provide recorded signals with 1 Vpp. References [1] Synopsys, I", "label": "poster"}
{"text": "Henrietta Swan Leavitt (7/4/1868 \u2013 12/12/1921) 1 2 5 6 8 9 10 3 4 7 11 1) Henrietta Leavitt working at HCO, circa 1900. Measuring Variable Stars 2) Plate a2969. Leavitt studied changes in variable stars by inspecting photos of the same section of sky taken on different dates. Photos were imaged through tele\u00ad scopes onto glass plate negatives coated in light-sensitive chemicals. (The bright\u00ad er a star, the more photons reached the plate and the larger its dark dot.) She labeled each star, measuring diameters through a loupe (magnifying glass). 3) Leavitt kept her analyses in handwrit\u00ad ten notebooks. For each plate, she would draw a detailed chart of the stars she was exam- ining as they appeared in the sky. (Mirror image to her markings on the back of the plate. See circled \u201cu\u201d and \u201cv\u201d.) 4) List of magnitudes for each labeled star on plate a2969. Stars were sometimes recalibrated. See 8. Comparing Plates 5) Detail from Plate b20650, exposed for 4 hours on October 20, 1897. Henrietta Swan Leavitt, a deaf American astronomer and graduate of Radcliffe College, worked at the Harvard College Observatory (HCO) as a \u201ccomputer\u201d, examining glass photographic plates in order to measure and catalog the bright- ness of stars. This work led her to discover the relation between the luminosity and the period of Cepheid variables. Though she received little recognition in her lifetime, Leavitt\u2019s discovery later provided astronomers with the first \u201cstand- ard candle\u201d with which to measure the distance to faraway galaxies. 1 2 Williamina Fleming (5/15/1857 \u2013 5/21/1911) c e a d f 4 5 6 8 9 7 new variable 10 11a 11b 1) Portrait, circa 1890s. Fleming orga\u00ad nized the Draper Catalogue, classifying 10,498 stars, based on 28,266 spectra on 633 plates. By 1910, she had examined ~200,000 HCO photographic plates. 2) Orion Nebula in Glass Plate b10250 (de\u00ad tail), September 8, 1893 with markings by Fleming. 3) b10250 (detail), in which Fleming dis\u00ad covered the Horsehead Nebula. Fleming discovered 10 novae, 59 gaseous nebulae, ~ 300 variable stars, and was the first to recog\u00ad nize the existence of white dwarfs. 4) Photo of Horsehead Nebula; Ken Craw\u00ad ford, Rancho Del Sol Observatory. Note nebula color and position are reversed from negative in 3). Work With Variable Stars 5) Fleming\u2019s notes. She would draw a chart with the new variable, as well as stars near it (red box), then document positions & known magni\u00ad tudes (green). 6) Determining magnitude of new star (Plate i10491) using the \u201cPickering-Fleming Method\u201d (cyan box): Compare variable star \u201cv\u201d with a known, slightly dimmer star. Note how many Williamina Patton Fleming was the most famous woman astronomer in America during her lifetime. She helped develop a common designation system for stars and showed that variable stars and novae could be identified by their spectra, discovering many. A founding member of the Harvard Computers, a group of female astronomers and analysts at Har\u00ad vard College Observatory (HCO), she supervised other women astronomers and managed publications issued during her time there. A charter member of the Astronomical and Astrophysical Society, she advocated for women in astronomy. Read more about Williamina Fleming at https://library.cfa.harvard.edu/phaedra/fleming 3 The Project PHaEDRA Collection: An Anchor to Connect Modern Science With Historical Data Poster by: Peggy Wargelin, Project PHaEDRA, Wolbach Library, Center for Astrophysics | Harvard & Smithsonian Presented by: Edward Los, Harvard College Observatory, AAVSO Member ABSTRACT Project PHaEDRA (Preserving Harvard's Early Data and Research in Astronomy) is an initiative by the Wolbach Library, in collaboration with many partners, to catalog, digitize, transcribe, and enrich the metadata of over 2500 logbooks and notebooks produced by the Harvard Computers and early Harvard astronomers. Our goal is to ensure that this remarkable set of items, created by a remarkable group of people, is as accessible and useful as possi\u00ad bl", "label": "poster"}
{"text": "On behalf of PID Network Germany Felix Burger (TIB), Andreas Czerniak (UB Bielefeld), Barbara Fischer (DNB), Stephanie Glagla-Dietz (DNB), Lena Messerschmidt (Helmholtz Open Science Office), Heinz Pampel (Helmholtz Open Science Office / Humboldt-Universit\u00e4t zu Berlin, IBI), Jochen Schirrwagen (UB Bielefeld), Antonia C. Schrader (Helmholtz Open Science Office), Paul Vierkant (DataCite), Frauke Ziedorn (TIB) This work, excluding logos, is licensed under a Creative Commons Attribution 4.0 International. Funder: Authors & license: Project partners: 10 PID use cases in the project\u2019s focus About the project The goal of the project \u201cPID Network Germany\u201d is to build a network of existing and currently forming actors around Persistent Identifiers (short PIDs) in science and culture. The aim is to promote the application, implementation, standardization and interoperability of PID systems on a local, national and international level. The findings from the project will lead to recommendations in a national PID roadmap for Germany. The project started on March 01, 2023, and is funded by the German Research Foundation (DFG) scheduled to run for 36 months. The project website provides further insight into the goals of the project. Support & Contact \u2022 Website: www.pid-network.de \u2022 Contact: info.pidnetwork@listserv.dfn.de \u2022 Mailing list: PID Dialog Follow us on Social Media: \u2022 Mastodon: @PIDNetworkDE@openbiblio.social \u2022 Twitter: @PIDNetworkDE e. g. DataCite DOI, URN, Archival Resource Key (ARK) e. g. DataCite DOI, based on the metadata schema by the RDA WG PIDINST e. g. GND Why do we need PIDs? PIDs... \u2022 offer unique, universal, and permanent references to potentially any type of digital or non-digital entities in the research process. \u2022 enable linkage between entities. \u2022 contribute to the integrity of scholarly communication, its reusability and their reproducibility. \u2022 play a crucial role to make data FAIR. \u2022 provide a comprehensive overview of all entities in the research process. Netzwerk f\u00fcr die F\u00f6rderung von persistenten Identifikatoren in Wissenschaft und Kultur e. g. ROR ID, ISNI, GND, or for funding information (Gepris or Crossref Funder Registry), and for projects RAiD e. g. ORCID iD and Integrated Authority File (GND) e. g. Research Resource Identifier (RRID) for biological and the International Generic Sample Number (IGSN) for samples from all scientific fields e. g. DOI using the Citation File Format (CFF) e. g. DOI and URN service of the German National Library e. g. DataCite DOI, as suggested by ConfIDent (DFG-funded project in Germany) Logos by Julian K\u00fccklich (https://doi.org/10.5281/zenodo.5608845), licensed under CC 0 So far only few initiatives, such as re3data and FAIRsharing, are providing DOIs for research data repositories.", "label": "poster"}
{"text": "Lotte Wilms, Andreas Degkwitz, Caleb Derven, Marian Lefferts, Kirsty Lingstadt, Liam O\u2019Dwyer, Demmy Verbeke & Digital Humanities and Digital Cultural Heritage WG Participants 56 participants - 54 institiutions - 20 countries Full report available at doi.org/10.5281/zenodo.3247286 3. Select youractivitieswisely Libraries are most active in data capture, creation and storage. Build on your (collection) strengths to decide what works best for you. 1. Createa goal or visionforyourlibrary A defined framework clarifies your goal and manages expectations of partners. Set up your organisation with enough resources to make sure you can also reach this goal. 2. Measureyourimpact Identify early on how you will measure your achievements and impact. This will help you define what works well and what needs to be re-evaluated. 4. Reflectthefull breadthof yourcollections By broadening your scope to the full width of your collection your DH offering can be strengthened. Work from your strenghts and make access as easy as possible. 5. Have confidencein yourexpertise As the creator of your digital collections, you are the expert. Your are therefore the ideal partner, as you know what has been digitised, how it\u2019s been digitised, what licenses apply, what works well and what probably wouldn\u2019t. Strengthening the position of libraries as partner in DH will be a a core theme for the WG for the next two years. 6. Involveallyourcolleagues, notjusttheobviousones DH activities are most succesful if they are supported by a large number of library staff. Work together to build your skills and ideas. 7. Collaborate, collaborate, collaborate! Building your network in DH is crucial, as collaboration is key. Once you have defined your goals and activities go out and disseminate your data, your team and you ideas. Special thanks to Friedel Grant for the design of all graphs, tables and the word cloud. We also wish to thank all contributors and our WG\u2019s members for their input.", "label": "poster"}
{"text": "Genome Annotation using Nanopublications: An Approach to Interoperability of Genetic Data Rajaram Kaliyaperumal1, Peter A.C. \u2018t Hoen1, Zuotian Tatum1, Mark Thompson1, Erik Schultes1, Andrew Gibson1, Ivo F.A. C. Fokkema1, Johan T. den Dunnen1, Jeroen F.J. Laros1, Jos\u00e9 Luis Oliveira2, Pedro Lopes2, Pedro Sernadela2, Marco Roos1 1 Department of Human and Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands, 2 DETI/IEETA, University of Aveiro, Aveiro, Portugal Nucleotide change Substitutions Deletions Duplications Indels Single 22 2 - - Multiple - 6 4 1 Variant DB-ID gChange No.of TSS deleted SGCB_00043 g. 52886872_52904485del 1 DYSF_00176 g.71707370_71838047del 9 LMNA_00209 g.156052975_156100408del 12 promoter TSS exon inton CAGE cluster peaks", "label": "poster"}
{"text": "HELSINGIN YLIOPISTO HELSINGFORS UNIVERSITET UNIVERSITY OF HELSINKI DMP PROCESS AT THE UNIVERSITY OF HELSINKI HELSINKI UNIVERSITY LIBRARY In 2020, the Research Council of Finland changed its DMP submission process: 1) The DMP has to be submitted only by those applicants who receive a positive funding decision. 2) The RPO is responsible for ensuring that the DMP can be implemented and that the measures taken are in line with good data management practice. The UH receives approximately 100-130 positive funding decisions in relation to the largest funding call of the year - how do we manage the DMP review process at the university level? Tuija Korhonen tuija.korhonen@helsinki.fi Soile Manninen soile.manninen@helsinki.fi HULib Data Team/UH Data Support 25 86 216 165 0 50 100 150 200 250 2016 2017 2018 2019 Year of the call Number of DMPs, RCF\u2019s September call 2016\u2013 2019 (DMPs in the application phase) 137 112 103 0 50 100 150 200 250 2020 2021 2022 Year of the call Number of DMPs, RCF\u2019s September call 2020\u20132022 (DMPs after pos. funding decision)", "label": "poster"}
{"text": "Comparing two ways of generating 328 nm laser light for high-resolution spectroscopy of the S1/2 P3/2 transition in Ag Julius Wessolek1,2, Mitzi Urquiza3, Bram van den Borne4, Ruben de Groote4, Katerina Chrysalidis5, Kieran Flanagan1 and the CRIS Collaboration5 1) University of Manchester, 2) M Squared Lasers, 3) H\u00dcBNER Photonics GmbH, 4) KU Leuven, 5) CERN Spectra of the 532 nm, 856 nm and 656 nm pulses were taken with a scanning FPI (Toptica FPI-100) and the linewidths extracted. The linewidths of the 328 nm beams can be calculated as quadratic sums of the components: \u2206\ud835\udf08328\ud835\udc5b\ud835\udc5a \ud835\udc60\ud835\udc62\ud835\udc5a \ud835\udc53\ud835\udc5f\ud835\udc52\ud835\udc5e\ud835\udc62\ud835\udc52\ud835\udc5b\ud835\udc50\ud835\udc66= 177 \ud835\udc40\ud835\udc3b\ud835\udc67 \u2206\ud835\udf08328\ud835\udc5b\ud835\udc5a \ud835\udc51\ud835\udc5c\ud835\udc62\ud835\udc4f\ud835\udc59\ud835\udc52\ud835\udc51 \ud835\udc43\ud835\udc37\ud835\udc34= 387 \ud835\udc40\ud835\udc3b\ud835\udc67 High resolution spectroscopy of Ag has been conducted at the Collinear Resonance Ionization Spectroscopy (CRIS) experiment at CERN ISOLDE to measure nuclear properties of the ground- and isomeric states. For spectroscopy of the S1/2 -> P3/2 transition in Ag, nano-second pulsed narrow-band 328 nm laser light has been produced in two different ways: Fig. 1: Sum frequency generation of narrow-band Ti:sapphire light with pulsed 532 nm light to generate 328 nm. Fig. 2: Second harmonic generation of pulsed amplified light from a cw OPO to generate 328 nm. Fig. 3: Ionisation scheme of Ag. The measured pulse lengths show that the pulses are in no case Fourier limited. This is expected for the 532 nm laser which is only actively temperature stabilized against drifts down to minute timescales. The PDA was pumped by that same laser and showed a shorter pulse length. The pulses from an injection-locked Ti:sapphire laser are usually broadened by cavity mode pulling and refractive index variation of the active medium. This leads to an instantaneous frequency shift and chirp and the pulse is not Fourier limited. \u2206\ud835\udf08\ud835\udc5a\ud835\udc56\ud835\udc5b= 90\ud835\udc40\ud835\udc3b\ud835\udc67\u226a274\ud835\udc40\ud835\udc3b\ud835\udc67 \u2206\ud835\udf08\ud835\udc5a\ud835\udc56\ud835\udc5b= 51\ud835\udc40\ud835\udc3b\ud835\udc67\u226a176\ud835\udc40\ud835\udc3b\ud835\udc67 \u2206\ud835\udf08\ud835\udc5a\ud835\udc56\ud835\udc5b= 9.7\ud835\udc40\ud835\udc3b\ud835\udc67\u226a17.2\ud835\udc40\ud835\udc3b\ud835\udc67 Fig. 5: Pulse lengths measured with a biased Si photodetector. The minimum spectral linewidths were calculated assuming Gaussian pulses and are all significantly smaller than the measured linewidths. Fig. 7: Spectra of the S1/2 -> P3/2 transition in 109Ag with 328 nm laser light produced in two different ways. The linewidths extracted from the spectra are ~ 250 MHz in both cases, contrary to the linewidths measured with the FPI. Figure from private communication with B. v. d. Borne. Spectra of stable 109Ag were taken with with both versions of the 328nm laser light at 6\u00b5W to minimize power broadening effects. The FWHM of the peaks is in the order of 250 MHz for both cases. This is contrary to the linewidth extracted from the FPI scans. For the summed light, small side peaks started to occur, suggesting not fully single mode operation. This could be caused by the implemented stabilization but it has to be investigated further. 109Ag with doubled PDA 109Ag with sum frequency generation Fig. 6: Scan of 109Ag with the 328 nm light from sum frequency generation. The regular side peaks are possibly from multimode operation. Fig. 4: Spectra of the different pulses, taken with a scanning FPI. The linewidth was extracted by fitting a Voigt profile to the peaks.", "label": "poster"}
{"text": "Drones above, Currents below: Using unmanned aerial systems for aerial systems to observe ocean surface current Take a closer look! Find supplementary details inside and a full copy of the poster on the back! The ocean surface measurement technique: UAS wave-based current mapping CONTACT INFO Vivek Bheeroo | Vbheeroo09@tamu.edu (603) 866-9406 A Mavic 2 Pro is deployed over the ocean surface. The drone is stabilized at an altitude of 120 m. The camera mounted to the drone records with a field of view of 55o. The resulting spatial dimensions of the acquired image sequence have approximate dimensions of 100 m x 75m. The image stack is divided into sub-windows of about 6 x 6 m. This procedure is shown in Fig. 1. A 3-dimensional Fast Fourier Transform (3D-FFT) is applied to the raw pixel intensities of the image stack in each sub-window. The 3D-FFT procedure is given by (1). Where I(x,y,t) is the intensity value at the point (x,y,t) in the spatio-temporal domain, F(kx,ky,\u03c9) is the complex value at the point (kx,ky,\u03c9) in the frequency-wavenumber domain, Nx, Ny, Nt are the dimensions of the 3D image data, kx and ky are the wavenumber vectors and \u03c9 is the angular wave frequency. The dispersion relation of a surface gravity wave describes the relationship between the wavenumber vector, k, and the angular wave frequency. This is shown in (2). For water waves that are influenced by an underlying current, U, the dispersion relation is expressed by (3). Fig. 1: Image acquisition and workflow breakdown Where h is the water depth and g is the acceleration due to gravity constant. For a wave field that does not experience interactions with an underlying current, (2) will form the dominant signal observed in the 3D FFT output in each sub- window. Typically, surface currents are present and influence the wave propagation. In these instances, (3) will manifest as the dominant signal in the 3D FFT output. To recover the ambient current in each sub-window, a fitting procedure is performed by applying a spectral energy-based maximization technique in the wavenumber-frequency domain. This is shown with a signal to noise ratio (SNR) optimization procedure in (4). Where Pw is the power related to surface waves, Pn is the power related to background noise, nw is the number of bins belonging to waves and nn is the number of bins belonging to noise. (1) \ud835\udc39\u0d6b\ud835\udc58\ud835\udc65, \ud835\udc58\ud835\udc66, \u03c9\u0d6f= \u0dcd\u0dcd\u0dcd\ud835\udc3c(\ud835\udc65, \ud835\udc66, \ud835\udc61) \u22c5e \u22122\u03c0i(\ud835\udc58\ud835\udc65\ud835\udc65 \ud835\udc41\ud835\udc65+\ud835\udc58\ud835\udc66\ud835\udc66 \ud835\udc41\ud835\udc66+\ud835\udf14\ud835\udc61 \ud835\udc41\ud835\udc61) \ud835\udc41\ud835\udc61\u22121 \ud835\udc61=0 \ud835\udc41\ud835\udc66\u22121 \ud835\udc66=0 \ud835\udc41\ud835\udc65\u22121 \ud835\udc65=0 (2) \ud835\udf14= \u0da5\ud835\udc54\ud835\udc8c\ud835\udc61\ud835\udc4e\ud835\udc5b\u210e(\ud835\udc8c\u210e) (3) \ud835\udf14= \u0da5\ud835\udc54\ud835\udc8c\ud835\udc61\ud835\udc4e\ud835\udc5b\u210e(\ud835\udc8c\u210e) + \ud835\udc8c\u22c5\ud835\udc14 (4) \ud835\udc46\ud835\udc41\ud835\udc45\u0d6b\ud835\udc48\ud835\udc65, \ud835\udc48\ud835\udc66\u0d6f= \u2211\ud835\udc43\u0d6b\ud835\udc58\ud835\udc65, \ud835\udc58\ud835\udc66, \ud835\udf14\u0d6f\ud835\udc64 \u2211\ud835\udc43\u0d6b\ud835\udc58\ud835\udc65, \ud835\udc58\ud835\udc66, \ud835\udf14\u0d6f\ud835\udc5b \ud835\udc5b\ud835\udc5b \ud835\udc5b\ud835\udc64", "label": "poster"}
{"text": "KARMAN-HOWARTH-MONIN EQUATION FOR COMPRESSIBLE HALL MHD TURBULENCE VICTOR MONTAGUD-CAMPS1, PETR HELLINGER1, ANDREA VERDINI2, SIMONE LANDI2, LUCA FRANCI3, EMANUELE PAPINI2, LORENZO MATTEINI4 1Astronomical Institute , CAS, Prague, Czech Republic, 2Universit\u00e0 di Firenze, Italy, 3Queen Mary University of London, UK, 4Imperial College, London, UK Contact e-mail: victor.montagud-camps@asu.cas.cz INTRODUCTION \u2022 The rate at which solar wind protons temperature decreases with heliospheric distance (Tp \u221d R\u22120.9[1]) is slower than the prediction for an ideal gas that expands adiabatically (Tp \u221dR\u22124/3). \u2022 The energy from large scale \ufb02uctuations driven by plasma turbulence towards smaller scales is one of the proposed mechanisms that could have a heating rate adequate to explain this difference. \u2022 The heating rate associated to turbulence is computed as the energy cascade rate, Q, that is, the net energy transfer rate between the scales at which turbulent non-linear interactions take place. \u2022 The K\u00e1rm\u00e1n-Howarth-Monin (KHM) equation is an accurate estimation of the energy cascade rate that can be directly derived from the compressible MHD equations using structure functions. \u2022 Our objective is to extend the estimation of the energy cascade rate given by the KHM equations to scales below the proton inertial length, di and assess the effect of turbulence anisotropy on the energy cascade rate estimation. VERIFICATION OF KHM FOR 2D COMPRESSIBLE HALL-MHD 10-1 100 101 102 -1.0 -0.5 0.0 0.5 1.0 l/di O = \u2212\u2202S/\u2202t/4+KMHD+KHall+\u03a8\u2212D [Q] \u2022 Initial simulation set-up: Simulation box of size 2562d2 i , and 20482 grid-points resolution. B0 along z. Alfv\u00e9nic \ufb02uctuations \u03b4Brms/B0 = 0.17 for kdi < 0.2. Zero cross-helicity, turbulent Mach M = 0.26 and \u03b7 = \u00b5 = 10\u22123. \u2022 KHM equations terms are normalized to Hall- MHD heating rate Q \u2261\u27e8\u03b7\u2207B : \u2207B + \u03c4 : \u2207u\u27e9. \u2022 KHM equation holds, but non-linear terms do not show a clear inertial range, i.e., they are not con- stant over an extended range of scales. KHM ANISOTROPY ON 3D COMPRESSIBLE HALL-MHD \u2022 Initial simulations set-up: two simulation boxes of size 323d3 i , and 5123 grid-points resolution. B0 along x. One demagnetized |B0| = 0 (3D Iso) and the other one magnetized (3D ani) with B0 along z and Alfv\u00e9nic \ufb02uctuations \u03b4Brms/B0 = 0.2. Zero cross-helicity, turbulent Mach M = 0.1 and \u03b7 = \u00b5 = 6 10\u22124. \u2022 Top row: averaging over all increments (top row), demagnetized case is qualitatively similar to the 2D magnetized one. Non constant contribution from non-linear terms. \u2022 Bottom row: KMHD and KHall gyrotropized about B0 axis and 1D cuts \u03b8 = 0o, 30o, 60o and 90o with respect to B0. Anisotropic behaviour of both terms for |B0| \u0338= 0 run. REFERENCES [1] M. et al. Maksimovic. Anticorrelation between the Bulk Speed and the Electron Temperature in the Pristine Solar Wind: First Results from the Parker Solar Probe and Comparison with Helios. ApJS, 246(2):62, February 2020. [2] Petr Hellinger, Andrea Verdini, Simone Landi, Luca Franci, and Lorenzo Matteini. von K\u00e1rm\u00e1n-Howarth Equation for Hall Magnetohydrodynamics: Hybrid Simulations. ApJL, 857(2):L19, April 2018. [3] R. Ferrand, S. Galtier, F. Sahraoui, R. Meyrand, N. Andr\u00e9s, and S. Banerjee. On Exact Laws in Incompressible Hall Magnetohydrodynamic Turbulence. ApJ, 881(1):50, August 2019. DISCUSSION AND CONCLUSIONS \u2022 KHM equation for compressible Hall-MHD holds true for 2D and 3D simulations. \u2022 Magnetized plasma and 3D non-linear interactions were necessary to develop clear range for constant KMHD. For the same case, B0-aligned KHall contribution is observed above di. Box size effect or inverse cascade? \u2022 Higher resolution and smaller dissipation are still needed to show signi\ufb01cant Hall contributions below di KHM EQUATION FOR COMPRESSIBLE HALL-MHD Derivation of KHM equation[2,3]: evaluate Hall-MHD equations at two different points x\u2032 = x + l and x separated by an increment l. Subtract them and average over all possible increments. Hence, \u22121 4 \u2202S \u2202t + KMHD + KH + C + \u03a8 \u2212D = 0 Second order st", "label": "poster"}
{"text": "Control of clathrin-mediated endocytosis by NIMA family kinases Braveen B. Joseph*, Yu Wang+, Phil Edeen*, Vladimir La\u017eeti\u0107*, Barth D. Grant+ and David S. Fay* *Department of Molecular Biology, College of Agriculture and Natural Resources, University of Wyoming, Laramie, WY 82071 +Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854 Abstract Suppressor screen NEKL kinases are highly conserved members of the NIMA-kinase family, which have been predominantly implicated in cell division and ciliogenesis. We previously reported, that NEKL-2/NEK8/9 and NEKL-3/NEK6/7 are required within the C. elegans epidermis, and that their knockdown causes molting defects that results in larval lethality. In addition, we discovered a conserved set of ankyrin repeat proteins, MLT-2/ANKS6, MLT-3/ANKS3, and MLT-4/INVS, that partner with the NEKLs to regulate their intracellular localization. To better understand the mechanistic functions of NEKL-MLTs we obtained genetic suppressors of molting defects in nekl-2; nekl-3 double mutants. Strikingly, our screen identified several mutations that directly affect the activity of AP2, a conserved heterotetrametric adaptor complex required for clathrin mediated endocytosis. Knockdown of individual AP2 subunits, or an allosteric activator of AP2, FCHO-1, strongly suppress molting defects in nekl mutants. Conversely, mutations that increase the levels of active AP2 strongly enhance nekl molting defects. In addition, inhibition of nekls suppress morphological defects associated with reduced AP2 function, attesting to the tight functional connection between the NEKLs and AP2. To determine the functions of NEKLs in endocytosis, while avoiding potential confounding effects caused by nekl- mutant larval arrest, we used auxin inducible degradation methods to deplete NEKLs specifically at the adult stage. Loss of NEKLs led to greatly elevated levels of clathrin at the epidermal apical membrane and to a profound reduction in apical clathrin mobility. Adult NEKL depletion also adversely affected uptake of LRP-1, an epidermal cargo critical for molting. These results are consistent with depletion of NEKLs leading to a defect in the ability of vesicles to release clathrin after scission and suggest that NEKLs promote clathrin uncoating. Notably, both defects were largely alleviated by a reduction in AP2 or FCHO-1 activities. These findings suggest that reduced AP2 activity may facilitate clathrin uncoating and indicate that reduced AP2 activity suppresses nekl molting defects through the restoration of normal trafficking. Lastly, we show that human NEK6 and NEK7, orthologs of NEKL-3, can rescue both molting and trafficking defects in NEKL-3 depleted strains, suggesting that the control of intracellular trafficking is an evolutionarily conserved function of NEK family kinases. Individual knock down of \u00b5, a, and d subunits Model that NEKLs may promote closed AP2 Loss of NEKL changes epidermal clathrin localization Cargo trafficking is disrupted in NEKL-depleted adults \u237a-Flag \u237a-actin + + \u2013 \u2013 NEKL-2 ::AID NEKL-3 ::AID Auxin (20h) Auxin- Inducible Degron NEKL Auxin NEKL NEKL Ub Poly- ubiquitin TIR1 SCF Ub Ub Several suppressors connected to clathrin mediated endocytosis Dynamin Closed AP2 Open AP2 Cargo Clathrin Actin Auxilin Hsc70 Uncoating Plasma Membrane FCHO-1 FCHO-1 \u03c3 nekl-2; nekl-3; fcho-1(fd131) nekl-2; nekl-3; dpy-23(fd155) nekl-2(fd81); nekl-3(gk894345); Ex nekl-3+, GFP+ Allele nekl-2(fd81) nekl-2(fd90) nekl-2(fd91) nekl-2(gk839) nekl-3(gk894345) nekl-3(sv3) nekl-3(gk506) mlt-3(fd72) mlt-4(sv9) Change Y84L G88A Y84L G87A G88A Y84L G87A Deletion D228N P194L Deletion Deletion Splice Loss of function Weak Strong Moderate Null Weak Moderate Null Null Moderate MLT-4 Larval Molting MLT-3 NEKL-3 NEKL-2 MLT-2 Old Cuticle New Cuticle Shed Cuticle Synthesis \u03b1 \u03b2 \u03c3 \u03bc NEKL-3 NEKL-2 NEKL-3 NEKL-2 \u03bc \u03b1 \u03c3 nekl molting defects are suppressed by decreased function of the AP2 clathrin-adapter comple", "label": "poster"}
{"text": "6th International Conference on Recent Trends in Bioengineering (ICRTB 2023), 20th January 2023 MIT School of Bioengineering Science and Research Molecular Docking and Dynamics Studies of CDK1 against Epithelial Ovarian Cancer Drugs Asmita Jagadale, Shama Mujawar and K. Venkateswara Swamy* *Corresponding author : venkateswara.swamy@mituniversity.edu.in Epithelial ovarian cancer has been researched to be the most common and an aggressive form of cancer. Owing to its ability to evade detection until stage 3, when the cancer has metastasized extensively, it is important and crucial to find an effective treatment. Keeping this concept in mind, we implemented in silico analyses in the form of molecular docking and dynamics. The gene CDK1, the encoder of the protein that is a member if the Ser/Thr protein kinase family, is a catalytic subunit of the M-phase promoting factor (MPF), and a key player in the eukaryotic cell cycle. The protein encoded by CDK1 was chosen as a target for molecular docking, due to its existence as a significant hub gene from literature reviews. The ligands chosen were imipramine, trazodone, propafenone, resveratrol, alpha estradiol, levonorgestrel, apigenine, doxazosin, rottlerin, nortriptyline, prochlorprazine, noretynodrel, chlomipramine, fluphenazine, amiodarone, medrysone, piperlongumine, daunorubicin, vironostat, methotrexate and scriptaid, based on their potential evaluated by drug databases. The active sites of the protein were analysed using PDBSUM, and their neighboring amino acids were evaluated. The amino acids were observed to be Tyrosine 15A, Glutamine 81, Isoleucine 10A and Leucine 83A. The grid was calculated based on the coordinates of isoleucine, glutamine and tyrosine residues. Grid formation was done based on this location of the active site, and molecular docking was carried out using AutoDock Vina. The highest docking score observed was the protein against Doxazosin, showing a binding affinity of -10.4 kcal/mol. The interactions within the complex were observed using ProteinsPlus and Discovery Studio, and the interactions seen were among The results will be analysed and the best docked complexes were chosen to carry out molecular dynamics simulations using DESMOND. Molecular Dynamics CDK1 Retrieval of protein structure Retrieval of receptor structure Molecular Docking and analysis Result and analysis Virtual Screening Abstract Methodology Result: M o l e c u l a r D o c k i n g Molecular Dynamics Doxazosin Fluphenazine Medrysone Background Conclusion: Acknowledgement: We would like to thank to our honorable director Prof. Vinayak Ghaisas and our HOD Dr. Renu Vyas for their guidance and infrastructure support. \u2022 Ovarian cancer caused by stromal or germ cell tumors have high survival rates as compared to epithelial ovarian cancer. \u2022 Ovarian cancer rates are highest in woman aged 55-64. 3,13,000 New cases per year 2,00,000 Deaths per year 2D view of the docked complex 3D view of the docked complex The molecular docking and dynamics studies of CDK1 and FDA approved 21 drugs reveals that doxazosin against ovarian cancer is more effective. The present research work supports doxazosin usage is more effective as compared to other 20 drugs as it has lowest binding energy with -10.4 kcal/mol against CDK1. The C-alpha backbone of CDK is more stable through out 100ns within range of RMSD 1.6 to 2.2 A0 in additional doxazosin ranging from 1.62 to 2.0 A0 also stable at TIP3P water model constructed with cubic box 10 A0 at NPT conditions with 300K with Desmond, Schrodinger software.", "label": "poster"}
{"text": "Liu-Liu Shen, Gui-Rong Zhang, Wei Li, Markus Biesalski, Bastian J.M. Etzold 50. Jahrestreffen Deutscher Katalytiker, 15th \u2013 17th Mar. 2017, Weimar, Germany References: [1] P. Lodeiro, J. Barriada, R. Herrero, M.S. De Vicente, Environ. Pollut. 2006, 142, 264. [2] P. Apostoli, J. Chromatogr. B 2002, 778, 63. [3] Table of regulated drinking water contaminants. https://www.epa.gov/ [4] Guidelines for drinking water quality, 4th ed. World Health Organization: Geneva, 2011. [5] L. Shen, G. Zhang, W. Li, M. Biesalsiki, B. J. M. Etzold, ACS Omega in submission. Device fabrication: Modifier-Free Microfluidic Electrochemical Sensor for Heavy Metal Detection Heavy metals are hazard pollutants to the environment and impose severe risks to human health. Therefore, heavy metal detection is playing important role in environmental and clinical analysis. In this work, a simple, cost- effective and portable miniaturized electrochemical carbon-based sensor (\u00b5CS) is designed and proved to be highly sensitive towards Cd2+ and Pb2+ detection in aqueous solution. The \u00b5CS possess a novel 3D structure with working and reference electrodes directly facing each other but separated by the microfluidic paper channel. The electrodes in \u00b5CS are inexpensive graphite foil without any additional surface modifier such as mercury or bismuth. It is found that impressive low detection limits of 1.2 \u00b5g/L for Cd2+ and 1.8 \u00b5g/L for Pb2+ can be achieved on the \u00b5CS. The \u00b5CS also exhibits stable sensing performance up to 10 repetitive measurements, demonstrating the robustness of a sensing device for heavy metal detections. We believe that a proper design in the device configuration can completely eliminate the necessity to modify the working electrode by using additional surface modifier, which could provide new ideas for portable electroanalytical/sensing systems. Electrolyte: 0.1 M acetate buffer, pH=4.6 Individual detection of Cd2+ and Pb2+ \u00a7 Deposition condition: Cd2+: -1.2 V, 60 s Pb2+: -1.1 V, 180 s \u00a7 The limit of detection (LOD) are below the allowable limits in drinking water proposed by US Environmental Protection Agency (Cd: 5 \u00b5g/L, Pb: 15 \u00b5g/L) and World Health Organization (Cd: 3 \u00b5g/L, Pb: 10 \u00b5g/L). Stability and reproducibility of the \u00b5CS \u00a7 The deposition condition for simultaneous detection is (-1.2 V, 180 s). \u00a7 The detection limit is 6 \u00b5g/L for both Cd2+ and Pb2+. Conclusions: \u00a7 A modifier-free, low cost, reusable, electrochemical microfluidic carbon-based sensor was developed for heavy metal detection. \u00a7 High sensitivity and low detection limit at short detection time are obtained on the sensor during individual detection for Cd2+ and Pb2+. \u00a7 The high sensitivity may originate from the combined microfluidic configuration and novel 3D electrode layout, which may provide some new ideas for other portable electroanalytical/sensing systems. Structure analysis of the graphite foil Simultaneous detection of Cd2+ and Pb2+ \u00a7 Very good electrocatalytic stability was observed on \u00b5CS. Prof. Bastian J.M. Etzold (etzold@tc1.tu-darmstadt.de) Ernst-Berl-Institut f\u00fcr Technische und Makromolekulare Chemie Technische Universit\u00e4t Darmstadt 64287 Darmstadt Correspondence: This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement n\u00b0 681719) Electrochemical measurements 1. Metal deposition; 2. Square wave voltammetry Experimental Section Cd2+ Pb2+ LOD = 1.2 \u00b5g/L LOD = 1.8 \u00b5g/L \u00a7 The electrodeposited Cd species are selectively located at the edge positions of graphite flakes. WE, CE & RE: graphite foil Paper channel: filter paper, pore size 15 \u00b5m", "label": "poster"}
{"text": "The Library Treasure Hunt \u2013 Reach for the Stars! Introducing first-year students to the landscape of scientific information Eva Jurlander, Lund Observatory and Carina Enestarre, Physics and Astronomy Library Cajsa Andersson, Library of Chemistry and Chemical Engineering, Kristina Holmin Verdozzi, Physics and Astronomy Library, Nina Reistad, Department of Physics The students gather in the library and meet the library staff. The librarians give a quick presentation of the library and an introduction to the treasure hunt. The students receive a stamp on the treasure map from the librarian. They get their next assignment and continue on with their quest. Mission accomplished! Each student evaluates the hunt via a short poll and receives a treasure. The librarians thank the students and hope to see them soon again in the library. The students are divided into smaller groups and given their first assignment and a treasure map. OBJECTIVE \u2022 To make the first encounter with the library useful, fun and memorable for the students \u2022 To provide all students with a minimum level of information literacy CHALLENGES \u2022 The library competes with many other introductory activities for the first-year student. \u2022 To find an amusing way to introduce the library. METHOD \u2022 Learning by doing \u2022 Hands-on excercises \u2022 On the spot assessment and evaluation \u2022 Reward system OUTCOME \u2022 All students receive a positive first encounter with the library. \u2022 They get to know essential aspects of the library resources. \u2022 It opens up for further development of the student\u2019s information literacy. \u2022 The librarians get immediate input from the students. SUCCESS FACTORS \u2022 Close collaboration between librarians and teachers supported by the management \u2022 Making the library introduction an integrated and compulsory part of the course programme ADDED VALUE \u2022 Students practice team work \u2022 Interlibrary staff cooperation \u2022 Subject library profiling DEVELOPMENTS \u2022 Present new technology for example Ipads and e-readers to enhance the use of the digital collection. \u2022 The library should be an integrated part of all teachers\u2019 planning at all levels. The students carry out the missions together in groups and discover the physical and digital library collections and services. The students communicate their findings directly to the librarian who gives instant feedback. . 1 Photo: Francois Polito CC BY-SA 3.0 4 4 4 3 2 5 6 Highlight of the hunt! A view from top of the Observatory tower Sweden www.fysik.lu.se/english/library/treasure", "label": "poster"}
{"text": "MIT Open Access Articles FEDERATED LEARNING FRAMEWORK FOR NLP IN HEALTHCARE: ASSESSING HOSPITAL READMISSION USING ELECTRONIC HEALTH RECORDS The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Citation: Nalawade, Sahil, Samineni, Soujanya, Chowdhury, Alex, Feng, Ling, Umeton, Renato et al. 2023. \"FEDERATED LEARNING FRAMEWORK FOR NLP IN HEALTHCARE: ASSESSING HOSPITAL READMISSION USING ELECTRONIC HEALTH RECORDS.\" Conference Poster at Bio-IT World, Boston, 2023 (May). As Published: https://www.bio-itworldexpo.com/poster-presentations Persistent URL: https://hdl.handle.net/1721.1/151725 Version: Author's final manuscript: final author's manuscript post peer review, without publisher's formatting or copy editing Terms of Use: Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.", "label": "poster"}
{"text": "Enabling open research practices - connecting Octopus with research repositories Dr Agustina Mart\u00ednez Garc\u00eda, John Kaye, Dr Alexandra Freeman Open practices \u00a7 The research landscape is evolving rapidly, with a wide range of tools and platforms being developed to enable open research practices, and increased expectations from funders to openly share research outputs. \u00a7 Repositories play a critical role to ensure discoverability, access and long-term preservation of research outputs Using open and well-adopted standards, this collaborative project aims to increase interoperability between innovative research publishing tools like Octopus and remove barriers to depositing research outputs into research repositories. The project uses the DSpace platform as the case study. Octopus overview \u00a7 Octopus is a new scholarly publishing platform designed to incentivise best practices in research \u00a7 Open and free to use: all publications and the source code itself are available under open access licenses \u00a7 Its unit of publication is not a traditional \u2018paper\u2019 but instead one of eight constituent units supporting the research lifecycle stages \u00a7 Open, post-publication peer review, with red- flagging capabilities, to assess quality and integrity What we will do \u00a7 The project will produce an implementation case study using Apollo repository (DSpace) \u00a7 Develop deposit mechanisms into repositories via Jisc Publications Router native API \u00a7 Align with COAR guidelines by implementing a Resourcesync endpoint - Users will be able to view Octopus outputs via repositories or content aggregators Key benefits \u00a7 Reassure researchers of their outputs being available and preserved for the long-term \u00a7 Facilitate tracking of research impact through linking outputs together \u00a7 Support institutions with funder compliance and reporting CRIS integrations via Jisc Publications Router Apollo (DSpace), Cambridge\u2019s trustworthy repository Figure placeholder References 1) Octopus, https://www.octopus.ac/ 2) JISC Publications Router, https://pubrouter.jisc.ac.uk/ 3) DSpace Repository Platform, https://dspace.lyrasis.org/ 4) UK Reproducibility Network, https://www.ukrn.org/ Octopus Apollo Scan the QR code to download the poster Dr. Agustina Mart\u00ednez Garc\u00eda am857@cam.ac.uk John Kaye John.kaye@jisc.ac.uk Dr. Alexandra Freeman Alex.freeman@maths.cam.ac.uk", "label": "poster"}
{"text": "334 G077 European consumers\u2019 purchase intentions towards plant-based meat products: the mediation effect of social media involvement. Listia Rini1, Simoun Bayudan1, Ilona Faber2, Michael Bom Fr\u00f8st2, Federico J. A. Perez-Cueto3, Joachim Schouteten1, Hans De Steur1 1Ghent University, Belgium. 2University of Copenhagen, Denmark. 3Ume\u00e5 University, Sweden Abstract The OECD projects that by 2031, meat supplies will elevate to almost 400 MT to meet global demands, correspondingly increasing total greenhouse gas (GHG) emissions by 9%. Meat consumption has been associated with many health adversities, such as diabetes and cardiovascular disease. The environmental and health challenges related to meat production and consumption have thus contributed to the rise of new plant-based food (PBF) products. In Europe, the market growth of PBF products is encouraging, with a total sales value of around EUR 3.6 billion in 2020. Plant-based meats (PBM) are some of the most popularly developed PBF products, with countries such as France, Germany, the Netherlands and Sweden already producing and marketing their own PBM products to European consumers. However, European consumers\u2019 acceptance of PBM products is generally lower than conventional meat. One of the barriers to PBF consumption is related to consumers\u2019 information needs, but social media (SM) can nowadays help alleviate these needs through information dissemination. Therefore, the objective of this study is to investigate whether consumers\u2019 SM involvement mediates the relationship between consumers\u2019 pro-meat-reduction attitudes and their PBM purchase intention. Data were collected from European countries (AT, DK, FR, DE, IT, NL, PL, RO, ES, UK), with a total of 4589 omnivore respondents. Linear regression with mediation analyses was conducted via SPSS PROCESS v4.2 with pro-meat reduction attitudes as the independent variable and PBM purchase intention as the dependent variable. Two SM-related variables, namely likelihood to use SM to find PBF information and trust towards PBF information from SM were utilized as the mediators. Preliminary analyses showed that SM-related variables partially mediated the pro-meat reduction attitudes towards PBM purchase intention. The result suggests SM can be a driver to satisfy consumers\u2019 need of information regarding PBF products and increase their purchase intentions. Keywords Social media, Plant-based meat, Meat reduction, Purchase intention", "label": "poster"}
{"text": "Copyright 2019. The Trustees of Columbia University in the City of New York. This work is licensed under a Creative Commons Attribution 4.0 International License. Meeting the Challenges of the TRUST Principles for Digital Repositories Robert R. Downs 1 NASA Socioeconomic Data and Applications Center (SEDAC) Center for International Earth Science Information Network (CIESIN), Columbia University, 1 rdowns@ciesin.columbia.edu Prepared for Presentation to the 2020 ESIP Summer Meeting July 14-24, 2020, Virtual Event July 17, 2020 Poster Session The work reported here has been supported by the National Aeronautics and Space Administration under Contract 80GSFC18C0111 for the Socioeconomic Data and Applications Distributed Active Archive Center (DAAC). Endorsement of the TRUST Principles for Digital Repositories TRUST Principles for Digital Repositories* References Certification Programs CoreTrustSeal (2020) Nestor (2013) Audit and Certification of Trustworthy Digital Repositories. ISO 16363/CCSDS 652.0-M-1, https://public.ccsds.org/Pubs/652x0m1.pdf (2011). CoreTrustSeal Trustworthy Data Repositories Requirements. 2020. https://www.coretrustseal.org/why-certification/requirements/ ESIP Data Management Training Clearinghouse. 2020. https://dmtclearinghouse.esipfed.org/ Lehnert et al. 2019. Building Resilience by Sharing Infrastructure Among Data Facilities: An Initiative of the EarthCube Council of Data Facilities. https://agu2019fallmeeting-agu.ipostersessions.com/default.aspx?s=A6-0C-96-FA-24-07-F6-36-77-00-78-35-E6-7C-AC-51 Lin, D., et al. The TRUST Principles for digital repositories. Sci Data 7, 144 (2020). https://doi.org/10.1038/s41597-020-0486-7 Harmsen, H. et al. Explanatory notes on the Nestor seal for trustworthy digital archives. Nestor Certification Working Group, http://nbn- resolving.de/urn:nbn:de:0008-2013100901 (2013). Wilkinson, MD. et al. The FAIR Guiding Principles for scientific data management and stewardship. Sci. Data 3, 160018 (2016). https://doi.org/10.1038%2Fsdata.2016.18 Transparency To be transparent about specific repository services and data holdings that are verifiable by publicly accessible evidence. Responsibility To be responsible for ensuring the authenticity and integrity of data holdings and for the reliability and persistence of its service. User Focus To ensure that the data management norms and expectations of target user communities are met. Sustainability To sustain services and preserve data holdings for the long-term. Technology To provide infrastructure and capabilities to support secure, persistent, and reliable services. *Reproduced from Lin, et al., 2020. The TRUST Principles for Digital Repositories. Digital repositories, including scientific data centers, archives, and other data facilities must provide stewardship for the resources that they have been entrusted to manage and disseminate for their user communities. The tenets of transparency, responsibility, user focus, sustainability, and technology that are described in the TRUST Principles for Digital Repositories offer guidance for meeting the needs of users who can use research data, today, as well as succeeding generations of users (Lin, et al., 2020). Developed by several stakeholders from across the digital preservation and research data stewardship community, the TRUST Principles for Digital Repositories can be built upon by the broader community of data stewards to ensure that the data that are being collected now and in the future will be treated as valuable intellectual assets so that they are findable, accessible, interoperable, and reusable, as articulated in the FAIR Principles (Wilkinson, et al., 2016). Diligent digital curation and stewardship efforts will help to ensure that research data products and services can be used to continue scientific progress and achieve the societal benefits that such research can provide. Along with future stewards of research data and related resources, the digital repository professio", "label": "poster"}
{"text": "Continuing Large-Scale Global Trade and Illegal Trade of Highly Hazardous Chemicals Zhanyun Wang1,2, Hongyan Zou3, Tao Wang3, Zhong-Liang Wang3 1. EMPA \u2013 Swiss Federal Laboratories for Materials Science and Technology, 9014 St. Gallen, Switzerland, zhanyun.wang@empa.ch 2. Chair of Ecological Systems Design, Institute of Environmental Engineering, ETH Z\u00fcrich, 8093 Z\u00fcrich, Swtizerland 3. Tianjin Key Laboratory of Water Resources and Environment, Tianjin Normal University, Tianjin, P.R. China Methods Introduction \u00fc Chemical pollution, along with climate change and biodiversity loss, is causing in the triple planetary crisis. \u00fc To complement national/regional frameworks on chemicals, the Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade has been established. \u00fc For each listed chemical, all parties are required to make a decision as to whether they will allow future import of the chemical. Then, it is illegal to export the chemicals to a party that has decided not to further import them. However, the Convention does not have a formal mechanism to evaluate its effectiveness. \u00fc This study aims to capture an up-to-date, accurate, comprehensive overview of the global trade of highly hazardous chemicals listed under the Convention from 2004, when it entered into force, to 2019, to shed light on the Convention\u2019s impacts on the global trade of hazardous chemicals and provide insights on areas for improvement. Acknowledgements H.Z. acknowledges funding from the National Natural Science Foundation of China (NSFC grant no. 21906118), and Z.W. acknowledges funding from the European Union under the Horizon 2020 Research and Innovation Programme (project ZeroPM; grant agreement no. 101036756). View full article Continuing large-scale global trade of hazardous chemicals \u00fc The cumulative global trade of the 46 listed chemicals among all countries reached 64.5 megatonnes in 2004\u20132019. The highly hazardous pesticides and formulations had lower trade volumes (2.4 megatonnes), dominated by pentachlorophenol and its salts and esters (see Fig. 1, left). \u00fc It is an especially pressing problem for developing countries and countries with economies in transition (see Fig. 1, right). Main Findings \u00fc We develop and use a novel workflow of analysing trade records from the UN Comtrade database (79,194 entries), providing a minimum scenario of the global trade and illegal trade of 46 highly hazardous chemicals listed under the Convention. The workflow included: \u00fc an outlier analysis using clustering and statistical methods to identify erroneous trade records, and \u00fc a subsequent mirror analysis to reconcile asymmetric bilateral transactions. Complex geographical distributions of the global trade (see Figure 2) \u00fc Most of Asia were the major importers of pesticides chemicals, while U.S. and Middle East were the major exporters. Central and Western Europe were not only major importers but also big exporters of industrial chemicals. Prevalent illegal trade of hazardous chemicals (see Figure 3) \u00fc Defaulting was prevalent all over the world, especially in Central, Western and Southern Europe, South and Southeast Asia, and the Middle East. \u00fc In total, they accounted for 40% of the total trade volume (25.7 of 64.5 megatonnes), underlining insufficient effectiveness of the Convention. \u00fc The defaulting counts are seemingly on the rise over time. Tackling the global trade of highly hazardous chemicals \u00fc expanding the Convention\u2019s geographical coverage \u00fc enabling swifter listing of chemicals under the Convention \u00fc enhancing data availability, quality and accessibility \u00fc Understanding and addressing the \u201clock-in\u201d of hazardous chemicals Fig. 1 Trade volumes by chemical (a) and net imports by geographic region (b) of highly hazardous chemicals Fig. 2 Global transfer of the listed highly hazardous chemicals Fig. 3 Defaulting counts of the trade for exporting parties (countries) and counts of being ", "label": "poster"}
{"text": "Energy Reconstruction with Autoencoders for Dual-Phase Time Projection Chambers Ivy Li, Aar\u00f3n Higuera, Shixiao Liang, Christopher Tunnell | CHEP 2023 Energy Reconstruction for XENONnT References Weight Layer ELU(\ud835\udefc=1) x Weight Layer F(x) F(x) + x x identity Residual Block (ResBlock) ELU(\ud835\udefc=1) Input Hit Pattern (494,) Reconstructed Hit Pattern (494,) Latent Space Representation (50,) 5 ResBlocks (494,494) 1 LinBlock (494,50) 1 LinBlock (50,494) 1 LinBlock (494,494) ENCODER DECODER 5 ResBlocks (494,494) Inferring Number of Electrons in the Gas Gap Example Reconstruction of Top Array Hit Pattern , , Input Hit Pattern (494,) Reconstructed Hit Pattern (494,) Inferred ne True ne Loss = (1 - \ud835\udefd) MSE + \ud835\udefd MSE Loss Function with Cyclic Annealing Inferred ne True ne ENCODER: encodes input into a lower dimensional latent space\u2191 LATENT SPACE REPRESENTATION: constrains one value as the number of electrons in the gas gap but allows the others to evolve freely \u2197 DECODER: decodes input from latent space representation \u2191 LOSS FUNCTION: weighted sum of the mean squared error (MSE) losses below \u2193 CYCLIC ANNEALING: \ud835\udefd evolves from \ud835\udefd=0 (prioritize reconstruction) to \ud835\udefd=1 (prioritize latent space constraint) Weight Layer Linear Block (LinBlock) x ELECTRIC FIELD DRIFTS ELECTRONS TO GAS GAP: not all of the freed electrons from the interaction point reach the gas gap SCINTILLATION SIGNAL (S1): incoming particle interacts with xenon and causes a scintillation signal with energy which is proportional to the initial signal\u2019s number of photons IONIZATION SIGNAL (S2): electrons which reach the gas gap cause a brighter ionization signal with energy which is proportional to the number of electrons at the interaction point XENONnT has a detector target of 6 tonnes of ultra-pure liquid xenon [1] \u2197 HIT PATTERNS: Photosensors above and below measure signals \u2192 Future Work TOTAL ENERGY 6163194 trainable parameters Adam optimizer, starting learning rate 5e-4 Reduce learning rate by factor of 0.1 if loss does not decrease after 5 epochs Semi-Supervised Autoencoder DATASET: simulated hit patterns from a given [0, 2000] ne INPUT SIZE: 494 photosensors total TRAIN/VALIDATION/TEST SPLIT: 447500/447500/100000 hit patterns NUMBER OF ELECTRONS IN GAS GAP Inference Difference Normalized Difference DYNAMIC RANGE: autoencoder can reconstruct hit patterns well without normalizing or log-scaling hit patterns due to skip connections [3] ENERGY RESOLUTION: precise reconstruction is critical for rare event searches such as the search for dark matter evidence [2] INTERPRETABILITY: constraining the latent space to be physically meaningful e.g. a variational autoencoder constrains latent parameters as probability distributions \u2192 meaningful parameter uncertainties COMPUTATIONAL EFFICIENCY: simulating data through Monte Carlo methods is computationally expensive and time-consuming \u2192 ongoing efforts to create more ef\ufb01cient machine-learning algorithms for fast simulation [0] Check out our experiment! xenonexperiment.org [1] Aprile, E., et al. \"Search for new physics in electronic recoil data from XENONnT.\" Physical Review Letters 129.16 (2022): 161805. [2] Billard, Julien, et al. \"Direct detection of dark matter\u2014APPEC committee report.\" Reports on Progress in Physics 85.5 (2022): 056201. [3] Dieng, Adji B., et al. \"Avoiding latent variable collapse with generative skip models.\" The 22nd International Conference on Arti\ufb01cial Intelligence and Statistics. PMLR, (2019). GOAL TO IMPROVE RESOLUTION: the spread of the inferred number of electrons in the gas gap decreases as the inverse square root for increasing number of electrons \u2190 UNDERPREDICTION: WHY? currently the autoencoder underpredicts the number of electrons in the gas gap \u2191 Ground Truth Gas Gap Reconstructed True ne Inferred ne True ne (X) Inferred ne (Y) Counts", "label": "poster"}
{"text": "Spectral Model Components \u203a KERRBB [4]: The thermal spectrum of the accretion disc around a Kerr (rotating) black hole. \u203a SIMPL [5]: Converts soft disc photons to hard X-ray photons with a power-law spectrum expected for the disc corona. \u203a RelXill [6]: The ionised disc reflection, with relativistic effects. \u203a ISMabs [7]: Galactic absorption. Observations We use observations from March & September 2019: \u203a 3 from XMM-Newton (blue): \u203a rev3531, rev3533, rev3623 \u203a 8.5 ks, 11.3 ks, 56.3 ks exposure times. \u203a 2 from NuSTAR (orange): \u203a Simultaneous with rev3533, rev3623 \u203a 57.3 ks and 94.9 ks exposure times. rev3531 rev3533 rev3623 Fig 3. The Swift/BAT & XRT light curve of MAXI J1820+070. Fig 6. Mass posterior (grey) and prior (red). The Current Debate Different groups have reached very different conclusions, sometimes from the same data. These often correspond to the extreme cases: Model 1: \u203a Zero or low spin and/or \u203a A truncated disc (Rin \u2265 6 rg) Model 2: \u203a High (near maximal) spin (a > 0.9) \u203a Rin ~ 1 rg Fig 2. An overview of the two different, but extreme XRB models. Models like these are common in the literature, they all make implicit assumptions. Black hole Black hole Disc Disc Rin \u2265 6 rg Rin ~ 1 rg Where is the Inner Edge of the Accretion Disc? The location of the inner edge of the disc effects the spectrum in various ways: \u203a The luminosity and temperature profile of the thermal emission from the disc. \u203a The relativistic distortion on discrete features in the X-ray reflection spectrum, especially the Fe-K\uf061line. It is theoretically possible to use the detailed shape of the spectrum to infer the location of the inner edge of the accretion disc. These spectral effects are subtle and modelling them is subject to several assumptions. A Bayesian analysis of X-ray spectra from the black hole LMXB MAXI J1820+070 using XMM-Newton and NuSTAR. Abstract We adopt a fully Bayesian approach with the best available prior information, making use of the latest spectral models and the most accurate models of ISM absorption, using XMM-Newton RGS data. Our test case is the recently confirmed black hole LMXB MAXI J1820+070. We fit data over the 0.8 \u2013 70 keV range using XMM-Newton and NuSTAR observations. Fig 1. Structure of a low-mass X-ray Binary [1]. Sachin Dias, Simon Vaughan sdd9@leicester.ac.uk System Parameters Our modelling of MAXI J1820+070 includes proper priors on system parameters based on the best available radio through UV observations. System parameters are typically frozen or left entirely free, permitting other parameters to find unphysical values. \u203a Distance: A gamma prior based on VLBI measurements [2]. \u203a Inclination: A Gaussian prior from proper motion of ejecta [2] [3]. \u203a Mass: The mass function (\ud835\udc53(\ud835\udc40)), mass ratio (\ud835\udc5e) and inclination (\ud835\udc56) combine to give a shifted log-normal prior on the mass. \ud835\udc74\ud835\udc69\ud835\udc6f= \ud835\udc87\ud835\udc74 \ud835\udfcf+ \ud835\udc92\ud835\udfd0 \ud835\udc94\ud835\udc8a\ud835\udc8f\ud835\udfd1(\ud835\udc8a) \u203a Mass Accretion Rate: A Jeffreys prior between 10\u22126 \u1e40Edd and \u1e40Edd, calculated based on the 10th and 90th percentile masses respectively, assuming a standard accretion disc. References: 1. Image Credit: NASA/R. Hynes 2. Atri et al., 2020, MNRAS, 493, 81 Fig 4. Distance posterior (black) and prior (red). Priors are broader due to effects of unknown errors. Additional Priors We adopt additional priors for the parameters: \u203a Disc Colour Correction Factor (fcol): fcol is typically fixed at 1.7 [8]. Others argue the range could be broader [9] [10]. We assigned a gamma prior over the range [1, 10] with the highest density over [1.4, 2] [9]. \u203a Reflection Emissivity Indices: A gamma prior over the range [0, 10] with a mode at 3 (near Euclidean case) and 10-6 lower density at 10. Ne K-edge Fe L2-edge Oi K-edge Fe L3-edge Fig 10. XMM-Newton RGS spectrum for rev3531 (black) and rev3533 (red). \u203a ISM Column Densities: We fit XMM-Newton RGS spectra using ISMabs. H, O, Ne and Fe column densities were free parameters (having the largest effect in the 11 \u2013 24 \u00c5 range) with other column densities fixed (relative to H) to the values given in", "label": "poster"}
{"text": "Introduction Permaculture is an agricultural system, intended to be sustainable and self- sufficient, that uses natural ecosystems as a model. Permaculture is relevant on a global stage as the world\u2019s population is expected to grow to 10.5 billion people by 2050 (Reid 2017), creating an urgency for effective and sustainable agriculture. Beyond investigating how The Island School produces its food, this Permaculture study concentrates on food insecurity in the immediate vicinity of the Island School campus. At present, The Island School imports about 89% of the food. Permaculture practices seek to address the economic, environmental, and social issues prevalent in South Eleuthera and Small Island Developing States (SIDS). By finding possible solutions to Food insecurity and instability within The Island School\u2019s campus, Permaculture feeds into the larger global conversation regarding the negative environmental impacts of the global food system, the widespread food insecurity and instability, and the future of food in society. Permaculture: Planting Seeds of Sustainability on The Island School Campus Susanna Cabot, Isabel Cullen, Maeve Goodrich, Kelvin Monje, Kate Pausic, Ezra Stern, Nora Verdier Research Advisors: Joseph Plant, Leigh Schmitt Citations Garnett, T. 2013. Food Sustainability: problems perspectives and solutions. Proceedings of the nutrition society. 72,29- 39. Reid, J. 2017. Carbon Narrative. Waterfield Farms. Robards, C. 2017. Survey outlines food insecurity on Eleuthera. The Nassau Guardian. Tilman, D & Balzer, C & Hill, J & Befort, B. 2011. Global food demand and the sustainable intensification of agriculture. Proceedings of the National Academy of Sciences. 108; 50. Viviano, F. 2017. \u201cThis Tiny Country Feeds the World.\u201d National Geographic. http://www.nationalgeographic.com/magazine/2017/09/ho lland-agriculture-sustainable-farming.html. Methods The semester\u2019s research is focused around campus design and planning. The Permaculture Research Cohort cultivated and planted crops, added soil amendments, conducted animal husbandry, and informed the outside community through social media and a research blog. The Permaculture Team also collaborated with the dining hall and the Aquaponics team to prepare and serve a local meal for Parent\u2019s Weekend. Data and Results Throughout the semester, the Permaculture research cohort studied how to best communicate their scientific findings through social outreach. In addition, the group has been working on harvesting crops on the Island School farm that was then a part of the \u201clocavore\u201d Parent\u2019s Weekend meal. Campus Planning: Local Meal: Social Media and Outreach: Acknowledgements: We would like to acknowledge all those who have assisted us in our research, mainly the Permaculture research advisors: Leigh Schmitt and Joseph Plant, as well as the Farm Team, the Kitchen Team, and the Communications Team. We would also like to acknowledge the Aquaponics Research Group. Figure 8: A map of the United States shows the frequency of visits from each state to the Permaculture blog. Figure 4: Permaculture students clear a plot of land for agricultural use. Figure 6: The aquaponics system on campus produces leafy greens throughout the year for The Island School dinning services. Figure 1: The Island School has a model farm on campus designed with permaculture principles. Figure 3: The orchard near the CSD will be split up into sectors for a crop rotation. Figure 5: Radishes collected from Permaculture Research farm plots harvested in preparation for the Parents Weekend local meal. Figure 7: This graph shows the daily views of the Permaculture Research blog throughout the course of a week. Figure 2: Students filet tilapia from the Aquaponics system in preparation for the local meal. Permaculture Essential Questions \u2022 How do we feed ourselves? \u2022 What are the true costs (economic, social, environmental) to successfully growing food on campus? \u2022 For the long-term, what are the best and most logi", "label": "poster"}
{"text": "Last Year Before Death: Observations of SN 2020fqv by TESS and Friends Kaew Samaporn Tinyanont (UCSC), Ryan Ridden-Harper (JHU), Ryan Foley (UCSC), Viktoriya Morozova (PSU), Charlie Kilpatrick (Northwestern) Georgios Dimitriadis (Trinity), Armin Rest (STScI), Qinan Wang (JHU) on behalf of the Young Supernova Experiment (YSE) Collaboration. Early observations are key to understanding what happened in the last year prior to the star\u2019s death. SN 2020fqv was discovered within a day and we obtained the first spectrum 26 hr post-explosion. SN 2020fqv shows signs of interaction and is within an active TESS sector prompting us to trigger the first ultra-rapid HST program ever to obtain early-time UV-optical spectra with STIS and COS. The earliest STIS spectrum was obtained only 79 hr post-explosion. TESS captures the rise of this SN, allowing us to model it to constrain the explosion time and other properties of the explosion. SN 2020fqv comes from a red supergiant with a dense circumstellar environment. From the light curve fitting, pre- explosion image from HST (non-detection, F606W, shown on left), and late-time nebular spectroscopy (see different ranges of mass below), we are able to constrain that SN 2020fqv is an explosion of a red supergiant (RSG) with a zero-age main sequence mass (ZAMS) of 13.5-15 M\u2299. Further, the fast rise time and the early-time excess flux of SN 2020fqv, along with narrow emission lines in the spectra, point to a dense circumstellar medium (CSM) immediately outside of the progenitor star of SN 2020fqv. Circumstellar Medium of SN 2020fqv We find 0.23 M\u2299of CSM within 1450 R\u2299from the star. Modelling our observations shows that the density profile of the RSG progenitor of SN 2020fqv does not just drop off like normal at about 1000 R\u2299, but has a CSM component extending out to ~1450 R\u2299, containing ~0.23 M\u2299of material. The density and optical depth is so large that the SN shock only breaks out at the edge of this CSM, marked with a red cross in the bottom left figure. These CSM properties are not unusual among the population of SNe II (Morozova+ 2018). Our models show that the CSM is a result of an energy injection of 5x1046 erg into the envelope about 300 days before the explosion, which may be related to instability in late-stage nuclear burning (e.g., Quataert & Shiode 2012, Fuller 2017, Wu & Fuller 2021). The inner part of the CSM leaves an imprint on the SN\u2019s early light curve. Middle right figure compares the light curve models with and without the CSM. The data points are binned TESS light curve with uncertainty. The solid line model shows the light curve expected with the CSM component; it matches the data best. Bare RSG models (dashed and dotted-dash lines) cannot explain the entire light curve. This light curve is affected most by the bulk of the CSM inward of the shock breakout point. The outer part of the CSM forms narrow emission lines. Lower right figure shows the early-time spectra of SN 2020fqv both from the ground and from HST/STIS. They show the emission features around 4600 \u212bfrom high-ionization metal species like N III and C III. They originate from the outer CSM getting radiatively ionized by the shock breakout. These features have been observed in a growing number of CCSNe with early-time spectra, e.g. SN 2013cu shown here (Gal-Yam+ 2014). Select References: Morozova+ 2015, 2018, 2020; Vallely+ 2021; Jerkstrand+ 2014, 2018; Gal-Yam+ 2014, Wu&Fuller 2021, Fuller 2017, Quataert&Shiode 2012, Bowen 1935. SN shock breaks out from here Inner, optically thick, CSM Outer, optically thin, CSM", "label": "poster"}
{"text": "\u201cTHE SPINE\u201d \u201cTHE TORSO\u201d \u201cTHE ARMS\u201d \u201cTHE LEGS\" THE ANATOMY BEHIND TASK DESIGN WITHIN HIGHER EDUCATION Within the fundamentals of lesson planning in Higher Education, task design is vital to support student learning. The aim of the infographic is to provide \"THE SKELETON\" to assist the task design process for new academics. Claire Farquharson & Sarah Sandford, Hartpury University How does the task link to the lesson plan? Communicate this to the group. What Learning Outcomes does the task map too? Which transferable skills are embedded in the task? Think about how you can develop a range of skills across different tasks! For example working with others, presentation skills, team work. Do you need to \"scaffold skills\" for task success? For example if they are required to present information to a full group, have previous tasks assist them in presenting to to each other in pairs, then smaller groups first Identify any pre-task activities or previous learning that will assist students in completion of the task Do you need a ice breaker to help group dynamics? What are the clears aims of the task and it\u2019s duration? Is the task emphasising the level of study and expected skills? What\u2019s your exit task - take home messages! What type of task do you want to do? Is it a closed, structured task to identify key concepts? If it is a larger task, can this be split into smaller tasks first Is it more open, unstructured for students to apply their understanding of the concept in a wider environment and to create discussion? Through the group or individual task: How can we reinforce the concept? How can we get students to verify their understanding of the concept? How can we consolidate the concept, with context and relevance, to the group? How can you assist the student engagement? Can you get students to think individually, discuss in pairs and then share with a wider group. THINK - PAIR- SHARE. How can you assist group dynamics? Do you allocate groups? Choose groups? How do you identify roles within the tasks? How can they work with each other for a common goal? Consider the environment you are delivering the session in. Is it online or face to face? How does the environment work for you and them? Don\u2019t feel that you need to provide a variety of activities. Focus on the aim of the task and how it assists the lesson/module/unit more widely. What resources can you use to facilitate the task? Can this resource be collated for all the group to share and access after completion? Can you direct students for further resources and reading to support the task? \u201cTHE FINGERS & TOES\" Be innovative! Try different approaches! How did it go? Reflect on; Did the task achieve what you wanted? Were students engaged? Did you achieve the session aims? Did students improve their understanding? How did the task work within the session? What would you change or do differently next time?", "label": "poster"}
{"text": "Improved enhancer discovery in Drosophila and other insects Hasiba Asma1, Chad M. Jaenke2, Michael L. Weinstein2, Thomas M. Williams2 and Marc S. Halfon1 Introduction Transcriptional enhancers, or more broadly, cis- regulatory modules (CRMs), are essential building blocks of gene regulatory networks. We previously developed the SCRMshaw method for computational CRM discovery[1,2,3]. SCRMshaw uses the wealth of known D. melanogaster CRMs as training data to facilitate CRM discovery in not just Drosophila but in diverse holometabolous insects including mosquitoes, beetles, and bees. Here we present three approaches for increasing SCRMshaw\u2019s effectiveness. SCRMshaw: predicting CRMs (a) SCRMshaw takes a training set of similar CRMs and a set of similarly-sized non- CRMs as a background (BKG) set, (b) builds up kmer profiles of the sequence sets, (c) generates scores using statistical models , and (d) searches the genome for high scoring windows (predicted CRMs). 1. pCRM_eval: A comprehensive pipeline for in silico evaluation of CRM prediction approaches[4] 3. Iterative searching can serve to augment weak training sets to improve true-positive : false-positive ratios We used SCRMshaw on a small training set of 7 CRMs to identify CRMs within a gene regulatory network for Drosophila abdominal pigmentation. 1. Kantorovitz, Miriam R., et al.. Developmental cell 17.4 (2009): 568-79. 1. 2. Kazemian, M., et al. Nucleic Acids Res 39.22 (2011): 9463-72. 2. 3. Kazemian M, Halfon MS: CRM Discovery Beyond Model Insects.: Insect Genomics: Methods and Protocols; 2019: 117 3. 4. Asma H, Halfon MS:. BMC Bioinformatics 2019, 20(1):174. 4. 5. Suryamohan K, Halfon MS:. Wiley interdisciplinary reviews Developmental biology 2015, 4(2):59-84 1University at Buffalo-State University of New York, Buffalo, NY 2University of Dayton, Dayton, OH ~24000 CRMs pCRMeval compares prediction results with the existing extensive corpus of validated Drosophila CRMs to calculate recovery of true CRMs and estimate the specificity of a given method. pCRMeval can also assess the performance of a specific training set in terms of both sensitivity and specificity. 0 20 40 60 80 100 Training set sensistivity REDfly recovery Expression pattern specificity Percent Percent Percent Percent Training Set Sensitivity REDfly recovery Expression Pattern Specificity True Expectation True Expectation True Random Random Random Expectation Expectation Expectation True True A B C D 0 25 0 20 40 60 0 20 40 60 50 75 100 True Expectation Three measures of Assessment pCRM_eval demonstrates that SCRMshaw performs better than random expectations (A) Aggregate performance for 29 true training sets, 62 random training sets, and random expectation. Comparison of training set sensitivity (B), REDfly recovery (C), and expression pattern specificity (D) for true versus random expectations for each of the 29 training sets. 2. Toward individual prediction confidence scores A true CRM might be predicted in multiple related species. We are developing a \u201cweighted comparative confidence\u201d score to identify such conserved CRMs, even in the absence of sequence alignment. SCRMshaw Prediction SCRMshaw Prediction < 10kb SCRMshaw Prediction < 10kb Reference Species Genome Target Species 1 Genome Target Species 2 Genome [5] Assessment measures These 10 new validated CRMs were combined with the original 7 and the 2.5-fold expanded training set used for a new round of SCRMshaw prediction. Following is the summary of the results after getting predictions from updated training set. *Notably prediction results from updated training set contain all the previous true positives and only one false positive demonstrating a marked improvement in prediction specificity using the updated training data. Empirical testing of 18 SCRMshaw predictions revealed 10 true (e.g. Kr-h1) and 8 false positive (e.g. Pdp1) prediction results. Assessment measures In vivo validation Total No. of CRMs No. of CRMs predicted by original Training s", "label": "poster"}
{"text": "Planet gap opening across stellar masses Cat Sinclair (Cambridge), Giovanni Rosotti (Leiden), Cathie Clarke (Cambridge) Motivation and questions Many discs have rings and they may be due to planets. \u2022 How massive must a planet be to create a ring? \u2022 How does this vary with the distance from the star? \u2022 How does this vary with the host stellar mass? Theoretical expectation Depends on disc aspect ratio, i.e. temper- ature. Therefore varies with distance from the star and stellar luminosity Methods To verify the prediction, we do: \u2022 Dust and gas hydro simulations \u2022 Radiative transfer \u2022 CASA simulations to include ALMA observational effects Results Possible to use stellar mass with average luminosity, but keep in mind there is large spread in luminosities for any stellar mass. Luminosity spread in Lupus Theoretical expectations matched. Gap opening more difficult far from the star and for high stellar luminosities Conclusions \u2022 Gap opening more difficult far from the star and for high stellar lu- minosities. Quantitative expressions in the paper (QR code on the right) \u2022 Stellar luminosity crucial parameter for gap opening mass", "label": "poster"}
{"text": "Practice Abstracts Series BRANCHES #28 28 Monte Holiday Ecoturismo+Bosque - Regenerative tourism to prevent forest fires The company Monte Holiday Ecotourism has developed a set of coordinated actions in the tourist complex located in a privately owned holm oak forest in the mountainous area Sierra de Madrid, whose objective is to establish an adaptive forest management that allows both the prevention of forest fires and the energy recovery of the biomass obtained by means of the heating network of the campsite. In this way a double benefit is achieved, on the one hand the preservation and protection of the surrounding forest and people and on the other hand it contributes to achieve a neutral carbon footprint. The proposed forest management focuses on the selection and conservation of the trees that present best condition, including silvicultural treatments such as pruning and cutting to reduce the trees\u2019 density and the introduction of extensive livestock. The biomass obtained is used to produce renewable thermal energy for the comfort of visitors staying at the campsite. The \"MHE+Forest\" project aimed at energy self-sufficiency started 10 years ago with a hybrid solar/biomass heat network. Now, the installation has been expanded with a 99 kW photovoltaic plant and a 500 kW high-efficiency ETA boiler, which enables the recovery of biomass from forest management and ensures virtually zero emissions of particulate matter. In 2023, the first silvicultural intervention was carried out in the holm oak forest, obtaining 200 tonnes of green biomass. In the coming years, the adaptive management work will continue in accordance with the provisions of the forest management plan and higher volumes will be obtained. Part of the biomass will also come from nearby woodlands identified as being at high risk of fire spread by the campsite's self-protection plan. Monte Holiday Ecotourism aims to serve as an example of adaptive forest management that contributes to increase the resilience of the forest to climate change and forest fires while enabling the development of the local and circular bioeconomy and the production of renewable energy in the tourism sector, which also leads to savings in the campsite's energy bill (in 2022 over 30,000 \u20ac for an average consumption of 500 MWh of thermal energy per year, which implies a saving of over 50%). KEY WORDS Bioenergy, sustainable forest management, biomass, ecotourism COUNTRY Spain DISCLAIMER This Practice Abstract reflects only the author\u2019s view and the Branches project is not responsible for any use that may be made of the information it contains. LINKS www.intercambiom.org www.branchesproject.eu AUTHORS Maider G\u00f3mez Daniel Garc\u00eda Pablo Rodero Alicia Mira", "label": "poster"}
{"text": "Adapted from the Design made by pikisuperstar / Freepik \u201c \u201d A gateway to the European Open Science Cloud OpenAIRE Content Provider Dashboard: enabling trust and value within the EOSC repositories Authors: Andr\u00e9 Vieira, andre.vieira@usdb.uminho.pt Pedro Pr\u00edncipe, pedro.principe@usdb.uminho.pt OpenAIRE has received funding from the European Union's Horizon Europe Research and Innova\u019fon programme under Grant Agreements No. 101017452, 101017536. What is PROVIDE? Is the scholarly gateway that receives content registra\u019fon requests and provides guidance for content providers by viewing a personalised, user-friendly dashboard that shows the necessary steps and status of the services to complete the process. Bene\ufb01ts Extending repository metadata models to Open Science practices. Keeping the collections up-to-date: alerts, enrichments, additions. Fostering noti\ufb01cation-based and federated dissemination of knowledge. Improve Repository interoperability, collections and content visibility. Advance Institution memory & research assessment. Support Features Validator service and data source registration. Collection monitor to track the aggregation history. OA Broker service offers metadata enrichments. Usage Counts provides metrics (downloads and views) of data sources. h\u01a9ps://provide.openaire.eu Validate and register your data source using OpenAIRE authoritative registries Role in the EOSC onboarding Interoperability compliance via the OpenAIRE Guidelines. Every data source validated in OpenAIRE is EOSC compliant (Guidelines: v3.0, v4.0, data, CRIS) Integration of the data sources registration work\ufb02ow within the EOSC Research Product Catalogue OpenAIRE Graph becomes a key asset for discovery and monitoring within the EOSC: https://graph.openaire.eu/ OpenAIRE Support Learn more: www.openaire.eu/guides Ask a question: www.openaire.eu/helpdesk EOSC Providers Hub: https://eosc-portal.eu/eosc-provid ers-hub Instructions to EOSC onboarding: https://eosc-portal.eu/eosc-providers- hub/how-become-eosc-provider", "label": "poster"}
{"text": "THE DELIVERY STATUS OF JUNO 20\" PMTS AND THEIR PERFORMANCE Rong Zhao 1 (on behalf of JUNO collaboration) 1Sun Yat-Sen University zhaor25@mail2.sysu.edu.cn Abstract The Jiangmen Underground Neutrino Observatory (JUNO) [1] is a multi-purposed neutrino experiment currently under construction in South China. Due to its unprecedented requirement on the photocathode coverage rate in order to reach enough energy res- olution, totally 20k 20-inch photomultipliers (PMTs) will be de- ployed in the detector system, including 5k conventional Hama- matsu dynode PMTs(R12860) and 15k newly developed PMTs us- ing micro-channel plates (MCP-PMT) by North Night Vision Tech- nology (NNVT). The JUNO collaboration has developed a PMT mass testing system to characterize these PMTs and selected the qualified ones for the final installation. Up to now, we have re- ceived and completed the characterization of 5k Hamamatsu PMTs and 13.1k MCP-PMTs. In this poster, we will present the latest de- livery details and the performance results including the typical sin- gle photon-electron (SPE) waveform, SPE spectra of two types of PMTs, SPE resolution, photon detection efficiency(PDE) and dark count rate(DCR) etc. Introduction of JUNO Detector The JUNO central detector will be filled with liquid scintillator, about 15k 20\"MCP-PMTs and 5k 20\"Hamamatsu PMTs will be used to collect scintillation light and Cherenkov light; the geometry of JUNO detector and PMTs are shown in Figure 1. Figure 1:JUNO detector and geometry of Hamamatsu PMT and MCP-PMT PMT Delivery and Test Status By May 2020, 18k of the total 20k PMTs have been delivered to JUNO PMT storage site, the acceptance test of 15k PMTs have been finished and 5k MCP-PMTs have been potted, as illustrated in figure below. 13.1k delivered 10k tested 15k total 5k tested 5.3k potted HAMAMATSU DYNODE PMT NNVT MCP-PMT All of the delivered PMTs will experience a detailed visual check and electronic performance test before they are potted and finally installed into JUNO detector. PMT Testing System Two container PMT testing systems with electromagnetic shield- ing are currently used for mass acceptance tests[4]. Each of them consists of 36 individual drawers (see Figure 2). The PMT inside each drawer can be illuminated with a self-stabilized LED or a pico- second laser, both with 420 nm wavelength. Two PMT scanning stations [2][3] were built for characterization of whole PMT photo- cathode. It allows for the testing of individual PMTs in all relevant aspects by scanning the photocathode and identifying any poten- tial problems. Figure 2:The container PMT mass test system and PMT scanning station JUNO PMT Performance of tested PMTs The typical single photon electron waveform of Hamamatsu PMT and MCP-PMT is shown in Figure 3: 100 150 200 250 300 350 400 t[ns] 0 2 4 6 8 10 12 14 U[mV] 100 150 200 250 300 350 400 t[ns] 6 8 10 12 14 16 18 20 U[mV] Figure 3:typical SPE waveform and 2D waveforms of Hamamatsu and MCP-PMTs. left: wave- form of Hamamatsu PMT EA0419; right: waveform of MCP-PMT PA1707-1090 SPE charge spectrum of PMTs obtained by LED with low illumina- tion(average photon number \u00b5 \u22641 ) are shown in Figure 4: Figure 4:charge spectrum of PMTs. left: Hamatsu PMT EA0419 with gain=9.9E6 and \u00b5 = 0.16, 0.79; right: MCP-PMT PA1707-1090 with gain=1.04E7 and \u00b5 = 0.14, 0.84. Performance parameters of PMTs can be derive from the charge spectrum and other dedicated measurements. Table 1:peformance parameters of JUNO accepted PMTs PMT PDE(%) DCR(kHz) FWHM(ns) TTS(ns) resolution risetime(ns) falltime(ns) p/V Hamamatsu 28.17 15.38 11.56 1.42 0.28 6.94 10.20 3.83 MCP 27.20 48.94 8.18 6.35 0.32 4.01 17.97 4.28 MCP(HQE) 30.14 49.73 7.83 6.35 0.33 4.95 17.10 3.93 PDE and DCR Distributions The PDE and DCR(the methodology and the exact definition can be found in [4]) distributions of PMTs are shown in Figure 5, for MCP-PMT the high quantum efficiency version has higher detec- tion efficiency benefiting from the new photocathode technol", "label": "poster"}
{"text": "Characterising the detector response of the SuperFGD as part of the T2K near detector upgrade Tristan Doyle (on behalf of the T2K collaboration) tristan.doyle@stonybrook.edu 1. The T2K Experiment The Tokai-to-Kamioka (T2K) experiment is a long-baseline neutrino experiment based in Japan \u03bd\u00b5 (\u00af\u03bd\u00b5) beam produced at J-PARC, characterised by near detectors and detected at Super-Kamiokande Measures \u03bd\u00b5 (\u00af\u03bd\u00b5) disappearance and \u03bde (\u00af\u03bde) appearance 2. Near Detector (ND280) Upgrade Replace \u03c00 detector with three new sub-detectors: \u2192Super Fine-Grained Detector (SuperFGD): Highly segmented target material with ability to reconstruct neutrons and lower momentum protons \u2192High-Angle Time Projection Chambers (HATPCs): measure momentum, charge and particle ID with better angular acceptance than before See posters by Matteo Feltre and Ulysse Virginet \u2192Time-of-Flight (ToF): Precise timing information to reject backgrounds and improve reconstruction See physics capabilities in posters by Liz Kneale, Katharina Lachner and Weijun Li 3. SuperFGD Concept and Construction 2 million optically isolated 1 cm3 plastic scintillator cubes [1] 56,000 wavelength shifting (WLS) fibers \u2192Each coupled to a multi-pixel photon counter (MPPC) \u2192Three orthogonal fibers per cube Concept proven in charged particle [2] and neutron [3] beam tests Detector assembly at J-PARC October 2022 - April 2023: \u2192Cube layers installed with fishing lines \u2192Vertical alignment using metallic rods \u2192Fishing lines replaced with WLS fibers \u2192MPPCs and LED calibration system installed SuperFGD installed in October 2023 Find description of the electronics in poster by Viet Nguyen 4. Light Yield Measure ADC counts from electronics Can convert ADC counts to photoelectrons (p.e.) See poster on calibration by Daniel Ferlewicz For each hit there is a high gain (HG) ADC and a low gain (LG) ADC Linear relationship between HG and LG provides larger dynamic range Also measure time over threshold (ToT) for each hit Can convert ToT to HG using exponential relationship Provides even larger dynamic range than LG 5. Attenuation Length Having three fibers per cube allows construction of attenuation length plot \u2192More reliable characterisation of response and calibration For a given distance from the MPPCs, plot observed light from hits in cosmic events Fit distribution as a function of distance with an exponential function to extract attenuation length \u2192Measured attenuation length consistent with specification of WLS fibers 6. Time Resolution Select hits > 40 p.e. matched in all three dimensions Compare mean time of hit to mean time for event Gives \u223c1.2 ns time resolution \u2192Can be improved by electronics firmware update! 7. Neutrino Interactions in the SuperFGD Some of the first neutrino interaction candidates in the SuperFGD. Possible proton (left) and pion (right) candidates are highlighted. 7. Next Steps Continue tuning Monte Carlo simulation using measurements of light yield and attenuation length Measure dE/dx in the SuperFGD and make selection of proton candidates using Bragg peak Head towards first physics analyses with the SuperFGD! References [1] Y. Abreu et al 2017 JINST 12 P04024 [2] A. Blondel et al 2020 JINST 15 P12003 [3] A. Agarwal et al 2023 Phys. Lett. B 840 137843", "label": "poster"}
{"text": "MYRIAD-EU has received funding from the European Union\u2019s Horizon 2020 Research and Innovation Programme under Grant agreement ID: 101003276 Introduction MYRIAD-EU: Multi-hazard and sYstemic framework for enhancing Risk- Informed mAnagement and Decision-making in the EU Philip J. Ward, Marleen C. de Ruiter, Timothy Tiggeloven, Judith N. Claassen, Ruoying Dai While the last decade saw huge scientific advances in the understanding of natural hazard risk, most research and policy still address risk from a single-hazard, single-sector perspective not taking into account the interconnected reality of these events. MYRIAD-EU\u2019s vision is to catalyse the paradigm shift required to move towards a multi-risk, multi-sector, systemic approach to risk assessment and management. To achieve this vision, the overall aim is that by the end of MYRIAD-EU policy-makers, decision-makers, and practitioners will be able to develop forward-looking disaster risk management pathways that assess trade-offs and synergies across sectors, hazards, and scales. The project will focus on five multi-scale Pilot regions, in which we aim to better understand indirect, interregional, and cross-sectoral risk within Europe. Through this project we aim to reduce risks together: please contact us if you are interested in collaboration. Work Packages The MYRIAD-EU project is centred around eight Work Packages (WP\u2019s) summarized in Figure 1. Hazard Classes Geological Hydrological Climatological Biological Meteorological The following hazard classes are included in the project Pilots and Sectors The Pilots (see Fig.2) are selected to provide: a spread of different spatial scales, geographical locations, institutional settings across the EU; hazard ranges and hazard interrelation types (triggering, amplifying, consecutive, and compound). The key sectors that will be covered in MYRIAD- EU are: 1. infrastructure & transport 2. food & agriculture 3. ecosystems & forestry 4. energy 5. finance 6. tourism Partners Figure 1: Overview of MYRIAD-EU Work Packages (WPs) Figure 2: Overview of MYRIAD-EU Pilots #MYRIAD-EU Prof. Dr. Philip Ward philip.ward@vu.nl", "label": "poster"}
{"text": "\uf071Process \uf071Microstructural analysis after sintering at 1500\u00b0C \uf071Mechanical properties \u2022 Cold Crushing Strength determination (CCS): \u2022 Resonant Frequency Damping Analysis (RFDA): Beneficiaries Use of Metallurgical Residues as potential Raw materials for High Performance Refractory Castables Mathilda Derensy1, Thorsten Tonnesen1, Jong-Won Shin2, Jesus Gonzalez-Julian1 1. Institute of Mineral Engineering, RWTH Aachen University, Forckenbeckestra\u00dfe 33, 52074 Aachen, Germany 2. Calderys Deutschland GmbH, In der Sohl 122, 56564 Neuwied, Germany CESAREF PhD 04 : Industrial and Academic supervisors: Acknowledgements: Mathilda DERENSY MSCA Doctoral candidate mail: derensy@ghi.rwth-aachen.de This project has received funding from the European Union's Horizon Europe research and innovation program under grant agreement no.101072625 Goals: Results and Discussion: \uf0fcDevelopment of mineral processing route of aggregates and study of the behavior in refractory castables. \uf0fcFurther thermo-mechanical tests with castables containing vanadium slag as the bonding phase. \uf0fcDifferent trials to extract the vanadium in a sustainable way \uf0fcContact different slag suppliers for further comparison with current slag composition Ongoing work: \u2022 Strength decreases significantly when adding slag to the formulation but the reference is based on high alumina castables, rarely employed in industries \u2022 E and G modulus data do not display considerable deviation with the different amounts of slag \u2022 Vanadium reacts preferably with Mg, Al and Ca towards a stable phase after sintering and does not attack the alumina grains. Conclusion: Context: The steelmaking industry generates several by-products during the different stages of steel production. As a by-product, vanadium slag account for more than 60% of the world\u2019s overall production. However, it is tough to find vanadium in its pure state as it occurs in combination with various minerals. Using secondary resources for refractory castables solves the issue of natural raw materials, reduces costs related to their extraction and processing, and is friendly to the environment. Figure 1. Towards a new steel production route. Figure 2. Microstructure analysis of a castable with 0% slag; 2.5 wt.% slag and 2.5 wt.% cement and 5 wt.% slag after sintering at 1500\u00b0C for 6h and corresponding EDS scans of the different points on the graph. 1 2 3 4 5 6 7 O 56.28 57.09 57.56 55.28 57.02 56.68 57.55 Na 0.06 0.15 0.30 1.84 Mg 0.59 0.20 0.82 1.48 Al 39.54 39.40 42.44 41.16 42.98 38.88 37.55 Cl 0.19 Ca 3.25 3.16 3.07 3.27 1.37 V 0.28 0.35 0.21 Figure 3. Cold crushing strength experiment (Top) and resonant frequency damping analysis (Bottom) on castables after sintering at 1500\u00b0C/6h. 2.5 wt.% slag ; 2.5 wt.% cement 1 2 3 20 \u00b5m 5 wt.% slag 5 wt.% slag 6 7 100 \u00b5m 20 \u00b5m 0% slag (5 wt.% cement) 0% slag (5 wt.% cement) 4 5 20 \u00b5m 100 \u00b5m Advanced metal extraction of vanadium 2 min Dry mixing 5 min mixing Wet chamber 24h Demolding 1500\u00b0C 6h Dryer 24h Coarse Aggregate Fine Aggregate Porosity Matrix (ultra-fine) As coarse aggregates As bonding phase Castable Microstructure Raw Materials H2O + Deflocculant Mold Use Vanadium slag in castables composition Good properties to withstand harsh conditions Reducing emissions and costs related to extraction Reducing waste by recycling", "label": "poster"}
{"text": "SPHERE quality control and dataflow operations The first observing period Wolfgang Hummel, ESO, Data Management and Operations Division (DMO) SPHERE calibration plan Science templates One peculiarity of the SPHERE calibration plan are the science templates that generate in advance of the science data also calibration data valid for the particular pointing only. These include an optional image of the waffle pattern to reconstruct the source center behind the coronograph (called CENTER) , an optional source offset image for the flux calibration (called FLUX) and optional sky frames. Introduction Since April 2015 ESO operates the new planet finder instrument SPHERE (Fig. 1). SPHERE is one of the most complex instruments at the VLT. It consists of the common path and infrastructure (CPI) for AO and coronography and of three arms: IRDIS, IFS and ZIMPOL. A total of eight different observing modes is supported, each one with its own independent calibration plan and data association scheme. The modes include NIR differential beam imaging, integral field spectroscopy and differential polarimetric imaging with 30msec time resolution in the visual. [1] The first observing period of an instrument is usually the most critical phase in its life time, in particular in the context of quality control (QC) which is a task shared between science operations on site and the QC group in Garching. Here we report on the data flow design challenges, the QC system and operational highlights of the first six months of SPHERE operations. Operational Highlights: IFS light leakage We found a light leakage in the IFS-arm detector. As a consequence the dark calibrations show: \uf0a7 The dark current is linear function of DIT (Fig. 4, Box 4). \uf0a7 The dark current depends on the temperature at the optical bench (Fig. 4, Box 6). \uf0a7 The statistical noise measured is dominated by the shot noise introduced by the light leakage (and not by the readout noise ~3 ADU) \uf0a7 The statistical noise scales as square root with DIT (Fig.5, Box 4) ACKNOWLEDGEMENTS/REFERENCES Narrow band - broad band filter match The time to acquire day-time calibrations scales with the number of different instrument setups the observations use in one night, but the time window for taking day-time calibrations is confined due to operational reasons. Since it is justified for IRDIS and ZIMPOL to calibrate narrow band filter science observations with broad band filter day- time calibrations (covering the narrow band), this filter association was implemented for reasons to make use of these synergies. Insert other logos (optional) Fig.2: Left: Waffle pattern with the four cross points marked to find the center of the star behind the coronographic mask. CENTER calibration. Middle: Star at offset position, FLUX calibration. Right: Star behind the coronographic mask, science frame. Fig. 4: Sphere Health Check Plot to monitor QC parameters retrieved from DARK calibrations of the IFS-arm. The upper three boxes show the dark levels in ADU for three different DIT values. The lower middle plot shows the optical bench temperature with nearly the same pattern. The lower left box shows the linear dependence of the dark level with exposure time. (Cyan circles mark last entries.) The lower right box show the temperature dependence for the three mentioned exposure times (2sec, 8sec and 30sec). CONTACT Wolfgang Hummel Astronomical Data Quality Control Scientist ESO, Karl-Schwarzschild Str. 2, D-85748 Garching whummel@eso.org Live versions of the presented health check plots can be found here: Insert other logos (optional) Fig. 5: Sphere Health Check Plot to monitor QC parameters retrieved from DARK calibrations of the IFS-arm. The upper three boxes show the readout noise in ADU for three different DIT values. The lower middle plot shows the optical bench temperature with nearly the same pattern. The lower left box shows the square root dependence of the readout noise with exposure time. (Cyan circles mark last entries.) T", "label": "poster"}
{"text": "Elliott C. Shuppy University of Wisconsin-Madison School of Library and Information Studies Developing an Ecology-specific Research Data Management Workshop Acknowledgments: Thanks to Erin Carrillo, Brianna Marshall, and Ryan Schryver of University of Wisconsin-Madison Research Data Services References: Borer, E.T., Seabloom, E.W., Jones, M.B., & Schildhauer, M. (2009). Some simple guidelines for effective data management. Bulletin of the Ecological Society of America. 90: 2, 205-214. Michener, W. K. (2000). Ecological data: design, management, and processing. Oxford: Blackwell Science. Key Campus Unit Stakeholders \u2022 Research Data Services (RDS): Interdisciplinary organization committed to advancing research data management practice on the UW-Madison campus. \u2022 University of Wisconsin-Madison Center for Limnology (CFL): Research center dedicated to the study of fresh-water ecosystems and ecology programs, houses graduate students from zoology, ecology, and engineering. Problem: Research Data Literacy Graduate students from the University of Wisconsin Center for Limnology were awarded a grant funding from Integrative Graduate Education and Research Traineeship (IGERT) to host a research data management education workshop for graduate colleagues. Although data are used frequently by the graduate student group, sound data management practices and a thorough understanding of the importance of data stewardship are still challenges. Implication Facilitation Organization Conception \uf071 Proposal Initial development of the workshop was proposed to RDS by graduate student leaders from CFL in late spring 2014. RDS subsequently identified four of its own members to lead and plan the workshop. \uf071 Focus on ecology Data management practices in limnology share a considerable number of similarities with ecology. The planning stage of the workshop focused on collecting information about discipline and data workflow characteristics of ecology from published resources, conversations about the importance of teaching certain topics, and the graduate students\u2019 own personal beliefs and values associated with data management which were collected by survey prior to the proposal. \uf071 Needs One meeting with CFL graduate student leaders allowed RDS leads to gather support and input about attendee needs. Subsequent regular emails were sent to CFL leaders and audience members to gather more information about data management barriers and challenges. \uf071 Objectives RDS leads identified three objectives for the audience: 1) Increase awareness about RDS services 2) Expand data management proficiency with module content 3) Build understanding of complete data management workflow \uf071 Module topics and organization Based on models of ecological data workflows, topics selected and organized into a two-day workshop format. Day One (10am-4pm): Intro to RDS, spreadsheets, metadata, storage, file organization, and sharing Day Two (10am-12:30pm): Preservation and data management plans Hands-on work time was initially built into each module \uf071 Instructor selection The planning team chose several instructors from departments affiliated with Research Data Services who are likely to train future researchers on campus. Also chosen were instructors from ecology-associated departments who are likely to influence data management education for ecologists. \uf071 Realized module workflow Due to instructor schedules, and content overlap workshop modules were reorganized thusly: Day One (10am-2pm), November 10, 2014: Intro to RDS, spreadsheets, file organization & collaboration, and time allotted at end for collaborative work time Day Two (9am-12:30pm), November 11, 2014: Storage & preservation, data management plans, scholar presentation on ecology data management research \uf071 Activities Since hands-on activities were not practical for modules on the second day, time was allotted at the end of Day One to allow audience members to work with each other and instructors to garner feedback about data ma", "label": "poster"}
{"text": "Statistics of annotated validation dataset. Statistics of annotated validation dataset. The preliminary results of using Point Transformer trained on a public 3DEP point cloud classification dataset are promising. BACKGROUND: The USGS 3D Elevation Program (3DEP) is collecting lidar point data for the entire continental U.S. Minimum classification is following for current 3DEP. Accurately classified point clouds can support many down-stream applications such as in hydrologic analysis, urban planning, and forest management. This project will employ proven Deep Learning (DL) technologies in the development of a user-friendly open-source toolkit that will automate point cloud classification to refine and enrich the attributes of existing and future 3DEP data. MATERIALS and METHODS 1. 3DEP lidar data: National Map Download Client site (https://apps.nationalmap.gov/downloader/) 2. Training data: 2019 IEEE GRSS Data Fusion Contest (https://ieee-dataport.org/open- access/data-fusion-contest-2019-dfc2019) 3. DL model: Point Transformer 4. Validation RESULTS 1. Buildings and vegetation are now in different classes 2. Most of noisy points are re- classified/removed 3. Point Transformer had good performance in major classes (bare earth, vegetation, building) 4. The performance of the classes with fewer points (\u201cwater\u201d and \u201cbridge deck\u201d) was poor NEXT A deep learning-based point cloud classification tool on 3DEP PRESENTER: Jung kuan Liu (jliu@usgs.gov) Automated Deep Learning-based point cloud classification on USGS 3DEP LiDAR Data Using a Transformer Jung kuan Liu1, Rongjun Qin2 1 U.S. Geological Survey, Center of Excellence for Geospatial Information Science 2 Department of Civil, Environmental, and Geodetic Engineering, The Ohio State UniversityU.S. Department of the InteriorU.S. Geological Survey Alameda County, CA IoU Accuracy Num. of Points Bare earth 0.97 0.98 24.6 M Vegetation 0.86 0.89 3.6 M Building 0.84 0.98 3.2 M Water 0.19 0.26 254.9 K Bridge deck 0.44 0.47 88.5K Average 0.69 0.73 / Class # of points (original) # of points (re-labeled) % of points (re-labeled) Unclassified 12,911,236 405,179 1.26 Bare earth 18,317,594 24,580,630 76.47 Vegetation 0 3,601,862 11.20 Building 0 3,210,429 9.98 Water 194,817 254,956 0.79 Bridge deck 12,831 88,502 0.27 Noise 32,487 0 0 Others 672,593 0 0 Statistics of annotated validation dataset. Quantitative evaluation", "label": "poster"}
{"text": "(1) Xi\u2019An Jiaotong-Liverpool University ; (2) Leiden university; (3) Chinese Academy of Sciences; (4) Kavli Institute for Astronomy and Astrophysics at Peking University; (5) Zentrum f\u00fcr Astronomie der Universit\u00e4t Heidelberg Abstract Most stars in the Galaxy form in stellar groupings that either dissolve within several tens of millions of years, or evolve into open clusters. It is important to study the dynamics of planetary systems in such structures to explain the properties of observed exoplanets. Here, we numerically evolve open star clusters with planetary systems by combining the star cluster code NBODY6++GPU code with the planetary system code REBOUND. We use different sets of initial conditions, such as the virial ratio and stellar density, and evolve the system for 50 Myr. We find that stellar encounter properties, the star cluster density, and the planetary system architecture are the main factors that affect the evolution of the planetary systems. Although most planetary systems remain intact, others lose most of their outer planets, while some are stripped of all planets. Finally, we find that the presence of the planet Jupiter plays a prominent role in the survival chances of terrestrial planets. References [1] Lada 2003, A&A, 03011540 [2]Rein and Liu 2012, A&A 537, A128 [3] Wang, Spurzem et al,2015, MNRAS 450, 4070\u20134080 [4] Cai et al 2015, ApJ, 1506.0759 [5] hdfgroup.org [6] Cai et al 2017, 1706.03789 [7]Flammini Dotti et al 2020a [8]Flammini Dotti et al,2019 [9] Fujii et al 2019, A&A, 624, A110 [10]Flammini Dotti et al 2020b Initial Conditions Star Clusters: N= 500, 5000, 10000 stars; Q = 0.4,0.5,0.6; Rcluster = 1 pc; IMF Kroupa (2001), Plummer sphere, Standard Galactic Tidal Field Planetary Systems: ~1 MSun Host,: 6 planets (Earth, Mars and four gas giants), no protoplanetary disk, number of planetary system per star cluster, respectively, 25, 125, 200 Conclusions and Discussion We have carried out a set of N-body simulation in order to understand the influence of the star cluster on a Solar system-like planetary system. Most planetary system remain stable during the whole simulation, while most of the unstable one have ejected the outermost planets. The terrestrial planets are ejected mostly if Jupiter orbits gets perturbed, and it is completely destroyed with a impulsive encounter[8] . In the presence of a encounter, Jupiter acts both as dynamical barrier for weak encounters and as a perturber for the terrestrial planet for stronger encounters-. The final architecture of planets can be seen in the table, where the 1 and 2 planetary system are always, for all simulation and initial conditions, Jupiter for the 1 planet Solar system and Jupiter and Saturn for the 2 planet Solar system. The three planets scenario is unlikely for the empirical consequence of the Saturn presence in the 2-planets system. Black holes have also shown to impact the ejection of planets from their stellar systems[10]. Methodology We use REBOUND[2 ] as integrator for planetary systems and NBODY6++GPU [3] for the star cluster in order to model the gravitational dynamics, via N-Body codes, of both. The latter is using a C code environment, also working along with Python, optimised for few-body integrations, while the last is optimised for highly accurate and fast calculation and also supports MPI and GPU implementations, built for many-body integrations. We used 50 Myr as an evolutionary time, while 1000 years is the time-step for the star cluster output. The planetary output time-step is adaptive, and reproduces the previous 1000 years time-steps in the data storage, while it warns the user if the planets either escape or merge during this period (in short block time storage[4] ). We use the HDF5 format, which allows us to store data with high temporal resolution.[5] Finally the simulation can be resumed in 3 principal steps: star cluster and planetary system initial conditions, stars gravitational evolution with the nearby stars and plane", "label": "poster"}
{"text": "They have SCLC that has progressed or relapsed after at least two previous lines of therapy, including at least one platinum-based treatment They have a tumor tissue sample available They do not have unresolved side effects from previous treatments They have epNEC or LCNEC of the lung that progressed or relapsed, after at least one platinum-based treatment The cancer has spread to the brain and is growing uncontrollably They received a previous anti-cancer treatment that targets DLL3 They have interstitial lung disease, which refers to a group of diseases that causes inflammation and scarring of the lungs They have a weak immune system that struggles to fight off diseases. Also referred to as immunodeficient What is the percentage of patients whose tumors shrunk by at least 30% This is referred to as the ORR How long patients remain on treatment before the treatment stops working or the cancer progresses? This are referred to as DOR and PFS What are the side effects related to the treatment? These are referred to as TRAEs How long do patients live after the start of treatment? This is referred to as OS How often do the side effects occur? What are the effects of the treatment on the patients\u2019 quality of life? Disclosures This study was funded by Boehringer Ingelheim. This summary is based on a poster presentation at AACR-NCI-EORTC 2023, Boston, MA, USA, October 11\u201315, 2023. The authors were fully responsible for all content and editorial decisions of the associated infographic Congress presentation authors Valentina Gambardella, Alastair Greystoke, Martin Reck, Meiruo Liu, Martha Mueller, Ulrich Duenzinger, Emily B Bergsland, Taofeek Owonikoko Disclaimer: BI 764532 is an investigational agent and has not been approved by any regulatory authority Reference 1. Wermke M, et al. J Clin Oncol 2023;41(suppl 16):abstr 8502 Acknowledgments The authors thank the patients and their caregivers for making the study possible. Medical writing support for the development of this infographic summary was provided by Frans Everson (PhD) of Ashfield MedComms, an Inizio Company, and funded by Boehringer Ingelheim Abbreviations CD3, cluster of differentiation 3; DLL3, delta-like 3; DOR, duration of objective response; IgG, immunoglobulin G; ORR, objective response rate; OS, overall survival; PFS, progression- free survival; TRAEs, treatment related adverse events What is the study design? Where is the trial taking place? What is BI 764532 and why is it important? How does BI 764532 work? The DareonTM-5 study will test how safe and effective BI 764532 is in patients with SCLC, epNEC, or LCNEC of the lung at two dose levels that were selected during Phase I CD3 is present on immune cells called T-cells that are key to initiating immune responses. DLL3 is present on the surface of many SCLC, epNEC, and LCNEC of the lung tumors BI 764532 acts as a bridge between tumor cells and T-cells. When it binds to T-cells they become activated. Activated T cells release toxins and cytokines - substances that attract other immune cells - leading to tumor cell death DareonTM-5: An open-label Phase II trial of BI 764532, a DLL3-targeting T-cell engager, in patients with relapsed/refractory small cell lung cancer or other neuroendocrine carcinomas Who can take part in the study? What are the key questions that the trial will answer? Inactive T-cell CD3 DLL3 Cancer cell Human IgG- like structure BI 764532 anti-DLL3 anti-CD3 Given the promising activity of BI 764532 in patients with DLL3-positive SCLC, epNEC, and LCNEC of the lung (NCT04429087), researchers have designed a Phase II clinical trial called DareonTM-5 (NCT05882058). BI 764532 is an IgG-like \u2018T-cell engager\u2019 investigational compound. It binds to immune system cells and to cancer cells that express DLL3 Many tumors can grow unchecked by evading the immune system DLL3 is a protein found on the surface of some cancer cells but not on healthy cells Cancers that express DLL3 and could be targeted with BI 764532", "label": "poster"}
{"text": "UNIVERSITY OF LEEDS Results III The basic Microscale Model has been extended to include moist dynamics - including the contribution from latent heat exchange Exploring a cut-cell representation of terrain in a microscale model Abstract Moves to increasingly high-resolution models give rise to more variations in the underlying orography being captured by the model grid. Consequently, high-resolution models must overcome instabilities associated with terrain-following (see Fig. 1a) approaches. This work further explores the capabilities of a cut-cell representation of orography for idealised orographically-forced and moist microscale flows. The model is based on terrain-intersecting coordinates (see Fig. 1b) and solves flow in the resulting cut-cells using a finite-volume approximation. The model has been designed for the purposes of very high-resolution simulations. Comparisons with benchmark orographic and moist test cases demonstrate very good results. Further tests show the potential for the cut-cell approach for stably resolving flows over very steep orography. Institute for Climate & Atmospheric Science SCHOOL OF EARTH AND ENVIRONMENT, UNIVERSITY OF LEEDS S. Lock, A. Coals, A. Gadian, S. Mobbs Microscale Model is a research model for very high-resolution studies - of grid-resolutions \uf044x ~ \uf044z < 100m. The project has focussed particularly on flows over steep and complex terrain. The model is 3- dimensional, nonhydrostatic and fully compressible, with prognostic variables u,v,w,\uf050\u2019,\uf071\u2019. Integration is computed with a time-splitting approach (based on Klemp & Wilhelmson, 1978) using 2nd-order leapfrog for the long timestep and a 1st-order forward-backward scheme for the short step. A 2nd-order centred scheme is used for spatial differencing on a staggered grid (Arakawa-C in the horizontal, Charney-Phillips in the vertical). The orographic surface is represented by a piecewise bilinear function, and a finite-volume approach is used to solve flows through the resulting cut-cells. Background Cut-cells were first explored in environmental modelling by Marshall et al. (1997) for representing ocean-bottom topography. Results showed a piecewise linear representation of the surface compared favourably with step representations, particularly for surfaces that show large variation at the grid-resolution. The cut-cell work was extended to a compressible atmospheric model by Bonaventura (2000) and results were seen to compare well with a traditional terrain-following model. Steppeler et al. (2002, 2006) further extended the work, implementing a 3D piecewise bilinear representation of orography in a full atmospheric model (COSMO-DE). Tests showed good comparison with the equivalent terrain-following model, and studies of real cases showed evidence of improved precipitation forecasts from the cut-cell approach. Model equations describe a 3D, nonhydrostatic, fully compressible system. Written in time-split form, with fast modes (acoustic and gravity) on the LHS and slow modes on the RHS, the equations take the form: Cut-cell approach is based on the method discussed in Steppeler et al. (2002, 2006). The orographic surface is represented by continuous piecewise bilinear surfaces, that intersect the model grid \u2013 Fig. 2. The orographic surface results in some cells that are cut \u2013 partially beneath the surface; partially above. Flow through the cut-cells is solved by Fig. 1: Vertical levels in (a) a terrain-following, and (b) a terrain-intersecting grid a) b) Fig. 2: Example orographic surface intersecting a grid- column, from Steppeler et al. (2006) using a finite-volume method to compute the divergence term in the pressure equation, using Gauss\u2019s theorem over a volume V, bounded by surface area A: Applied to a cut grid-cell, the method requires the fluxes of the wind-field across the cell surfaces. For surfaces that coincide with the grid, the wind components are conveniently located (staggered grid), and there is zero flux across the orographic", "label": "poster"}
{"text": "The sage2 Project has received funding from the European Union\u2019s Horizon 2020 research and innovation program under grant agreement 800999 Sage2 \u2013 Percipient StorAGe for Exascale Data Centric Computing Consortium: 9 partners led by Seagate (UK) Ltd. covering technology providers, computing centres and application providers and users Objective: Design an exascale ready architecture based on hierarchical storage layers and object storage (MERO), adaptable to novel storage media . Justification: I/O can represent a bottleneck in many applications . This bottleneck can be addressed by facilitating use of fast but expensive storage media in an hierarchical architecture. The use of storage-class memory additionally to spinning disks blurs the line between byte addressable and block data store Unique Features: \u2022 Containers for treating many objects the same \u2022 Distributed Transaction Management \u2022 Supports global memory abstraction \u2022 Integrated AI framework \u2022 Function shipping to move processing to the data \u2022 Data Aware Scheduling based on SLURM \u2022 QoS based Architecture Global Memory Abstraction: applications, tools and programming models access data on the SAGE system either directly by mapping objects to memory in the tier nodes, or, by accessing them as a storage system through the Clovis API. Three scenarios envisaged: \u2022 Make NVRAM-C (NVRAM within compute nodea) appear as a single addressable space \u2022 For larger objects, make use of external NVRAM (NVRAM-E), directly accessing using RDMA \u2022 Using standard MERO APIs to access data in any tier Under Development: \u2022 Differential checkpointing of objects to back them up to lower level storage \u2022 Data Reshaping to allow restart with different numbers of nodes Co-Design: SAGE architecture has been co-designed with application developers and users. Applications cover \u2022 Space weather (IPIC3D) \u2022 Satellite Data Processing (J\u00dcRASSIC) \u2022 Finite Element Modelling (paraFEM) \u2022 CFD (BOUT++) \u2022 Neural Simulation Tool (NEST) \u2022 CAT (Savu) Application Support and Programming Models ARM have developed extensions to their Allinea Forge toolkit and are supporting integration of MERO onto ARM processors. Kitware are adapting their visualization tools to optimize user experience when analysing results on SAGE. Current and Future Status: \u2022 Prototype system installed and operational at J\u00fclich Supercomputing Centre \u2022 MERO object store under consideration for Open Sourcing S. de Witt1, D. Samaddar1, A.Davis1, S. Narasimhamurthy2, G. Umanesan2, D. Pleiter3, M. Salem El Sayed3 1 United Kingdom Atomic Energy Authority 2 Seagate (UK) Ltd 3 J\u00fclich Supercomputing Centre", "label": "poster"}
{"text": "Optofluidic Force Induction Scheme for the Characterization of Nanoparticle Ensembles Marko \u0160imi\u0107,a,b Gerhard Prossliner,b,c Ruth Prassl,c Christian Hill,b,c Ulrich Hohenestera a Institute of Physics, University of Graz, Austria; b Brave Analytics GmbH, Austria; c Gottfried Schatz Research Center, Division of Biophysics, Medical University of Graz, Austria Abstract Momentum transfer from light to matter provides the basic principle of optical tweezers. Most studies have hitherto employed this principle for trapping and manipulation of single nanoparticles. However, in a microfluidic channel one can also monitor the effect of optical forces exerted on ensembles of dielectric nanoparticles, to acquire knowledge about various nanoparticle parameters, such as size, shape or material distributions. Here, we present an optofluidic force induction scheme (OF2i) for real-time, on-line optical characterization of nanoparticles. Our experimental setup builds on precisely controlled fluidics as well as optical elements, in combination with a focused laser beam with orbital angular momentum. By monitoring the single particle light scattering and trajectories in presence of optical and fluidic forces, we obtain detailed information about the properties of the individually tracked particles. We analyse the trajectories using a detailed simulation approach based on Maxwell\u2019s equations and Mie\u2019s theory, in combination with laser fields and fluidic forces. We discuss the basic physical principles underlying the OF2i scheme and demonstrate its applicability. Our results prove that OF2i provides a flexible work bench for numerous applications. Introduction Here we employ optofluidic forces on ensembles of nanoparticles using a laser tuned at 532 nm with precise micro-fluidic pumps. Both, optical and fluidic components generate forces acting on dielectric nanoparticles as shown in figure and . Under certain conditions, particles are constrained to a 2D-optical trap and travel along characteristic trajectories, see figure . Single-particle trajectories shown in are processed in real-time by recording single particle light scattering via an ultramicroscope setup and a CMOS camera. References [1] Ashkin A. A., PNAS 1997 , 94 , 4853 - 4860 [2] C. Hill. (2020). EU Patent No. 3422364B1. European Patent Office. [3] A. D. Kiselev and D. O. Plutenko, Phys. Rev. A 2014, 89, 043803. Institute of Physics Brave Analytics GmbH Gottfried Schatz Research Center Author Mail: marko.simic@uni-graz.at Methods In order to simulate particle motion within our capillary, we perform a multipole expansion of the incoming fields and solve for the scattered fields employing Mie\u2019s theory for Laguerre- Gaussian beams. The time-averaged optical forces are computed by where is Maxwell\u2019s Stress Tensor. The integration is performed using the total fields and a Gauss- Legendre quadrature for spherical particles with and being material constants. Results The experimental data for 400 nm Standard-Latex particles is compared to simulated velocities and depicted in figure . The resulting size distributions are shown in figure for mono- and polydisperse samples. We compare our results to those of Nanoparticle Tracking Analysis (NTA). Discussion The OF2i scheme is presented with its underlying physical principles together with a theoretical description based on Mie\u2019s theory and higher order Laguerre-Gaussian modes. Our results show very good agreement between experimental and theoretical data on the example of various standardized Latex particles. Furthermore, we prove the working principle of OF2i and demonstrate its applicability to various nanoparticles. Simulations We now combine Newton\u2019s equation of motion with Stokes\u2019 drag and obtain for the particle\u2019s velocity at any position within the capillary. Integrating particle velocity, we obtain the corresponding trajectory using a Runge-Kutta scheme. Figure shows selected trajectories for 200 nm, 400 nm, 600 nm and 900 nm using above\u2019s ", "label": "poster"}
{"text": "Figure t Introduction Methods References Cortical synchronization controls EEG Trough-max vs EEG Peak-max Funding / Conflicts of Interest Disclosure A B C D E F 50 -100 50 -100 Single PYdr Voltage Zoomed TC\u2192PY AMPA current Single TC Voltage Mean TC\u2192PY AMPA current [\u03bcA/cm2] [\u03bcA/cm2] [mV] [mV] 1.5 0 1.6 1.40 1 2 Time [sec] 0 0 0 2 2 2 \u03c0 -\u03c0 0 Alpha Amplitude (12 Hz) SWO Phase Bin (1.0 Hz) Un-normalized Modulation Index 30 5 G H I 50 -100 50 -100 Single PYdr Voltage Single PYso Voltage Mean PY\u2192PY AMPA current [\u03bcA/cm2] [mV] [mV] 0.03 00 0 0 2 2 2 1 Time [sec] J \u03c0 -\u03c0 0 Alpha Amplitude (12 Hz) SWO Phase Bin (1.0 Hz) PY\u2192PY Comodulogram 0.1 0.03 0 15 Time [sec] 7.5 K Coupling Map 0.5 1 Alpha Frequency 8 10 12 SWO Frequency 1.5 2 2.5 Un-normalized Modulation Index 0.2 0.8 EEG Trough-max Spike Rastergrams EEG Peak-max Spike Rastergrams Austin E. Soplata1,2,3(austin.soplata@gmail.com), Michelle M. McCarthy2,3, Erik Roberts1,2, Emery N. Brown2,4,5,6,7, Patrick L. Purdon2,4,5, Nancy Kopell2,3 Cortical UP/DOWN state synchrony drives propofol phase-amplitude coupling in slow waves 289.18 / D4 1Graduate Program for Neuroscience, 2Cognitive Rhythms Collaborative, and 3Department of Mathematics & Statistics, Boston University, Boston, MA, 4Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, 5Department of Brain and Cognitive Sciences, 6Division of Health Sciences and Technology, and 7Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA Download this poster at: asoplata.com/asoplata-poster.pdf Or scan QR code here: \u2022 The anesthetic propofol induces beta (12-20 Hz), alpha (8-12 Hz), and Slow Wave Oscillations (SWO, 0.1-1.5 Hz) on the EEG of human patients [1] \u2022 At low propofol, near Loss of Consciousness, alpha amplitude is maximal during the trough of the SWO phase, called \"Trough-max\" phase- amplitude coupling (PAC) [1] \u2022 At high propofol, in deep anesthesia, alpha amplitude is maximal during the peak of the SWO phase, called \"Peak-max\" PAC [1] \u2022 SWOs in natural sleep often begin in the cortex [2], while simulations suggest propofol alpha is generated by the thalamus [3] \u2022 Propofol \"directly\" affects properties of thalamic and cortical cells and synapses such as GABA-A conductance, GABA-A decay time, and H-current conductance [1,3] \u2022 Propofol \"indirectly\" affects thalamic and cortical cells via decreasing cortical acetylcholine (ACh) [4], which affects K(Na)-current conductance, corticocortical, and thalamocortical synaptic strengths [5] \u2022 We hypothesized that the direct effects of propofol would produce and control both trough-max and peak-max PAC in a full, thalamocortical model, primarily by modulating thalamic behavior. However, we found that indirect effects from propofol on ACh and changes to the thalamocortical feedback loop could control trough-max vs peak-max changes. \u2022Our simulations modeled 100 cortical dendrite compartments (PYdr), 100 cortical axo-somatic compartments (PYso), 20 cortical interneurons (IN), 20 thalamic reticular neurons (TRN), and 20 thalamocortical neurons (TC) using the biophysical Hodgkin-Huxley formalism [3,5]. Synapses are connected via a nearest-neighbor radius. \u2022Our artificial EEG signal was modeled from the combination of AMPAergic corticocortical (PY\u2192PY) and thalamocortical (TC\u2192PY) synaptic currents onto cortical dendrites \u2022Our PAC analysis was based on the standard Modulation Index coupling measure [6] EEG Trough-max Involves Synaptic Competition \u2022 We found that while direct effects were necessary for thalamic propofol alpha, indirect effects were also necessary for SWO expression \u2022 EEG signal had two components: thalamocortical and corticocortical synapses onto cortical dendrites \u2022 In the thalamocortical synapse case: \u2022 Thalamic cells exhibit a persistent alpha oscillation, while target cortical cells exhibit a SWO rhythm \u2022 The TC\u2192PY synaptic current produces a Trough-max PAC signal since the alpha amplitude ", "label": "poster"}
{"text": "Pragmatic service development and customisation with the CEDA OGC Web Services framework (COWS) Stephen Pascoe, Ag Stephens, and Dominic Lowe British Atmospheric Data Centre, Rutherford Appleton Laboratory, UK (Stephen.Pascoe@stfc.ac.uk) Application: UK Climate Projections '09 User Interface http://ukclimateprojections-ui.defra.gov.uk COWS Architecture The CEDA OGC Web Services framework (COWS) emphasises rapid service development by providing a lightweight layer of OGC web service logic on top of Pylons, a mature web application framework for the Python language. This approach gives developers a flexible web service development environment without compromising access to the full range of web application tools and patterns: Model-View-Controller paradigm, XML templating, Object-Relational-Mapper integration and authentication/authorization. Application: QESDI Data Portal http://phobos.badc.rl.ac.uk/qesdi/ The QUEST Earth System Data Initiative (QESDI) facilitates exchange of data within the QUEST thematic programme. It provides access to a diverse range of data products produced within QUEST and complementary external datasets. The QESDI portal's data visualisation interface is driven by COWS WMS server and client components. Data download is available through WCS. Features: \u25cfOverlay WMS layers from internal and external WMS servers \u25cfBrowse arbitrary WMS dimensions \u25cfIntegrates with COWS Server to provide extended capabilities \u25cfStyling Options: contouring, colourmap configuration \u25cfData download via WCS KVP request \u25cfPublication quality plot generation \u25cfIntuitive display of Climatology dimensions QESDI map view showing WMS layer selection and styling options discovered from WMS GetCapabilities extensions. The contour plotting feature of COWS server facilitates overlay of overlapping layers. Geoserver (Java) Geoserver (Java) UI (PHP) UI (PHP) COWS-WPS (Python) COWS-WPS (Python) COWS-WMS (Python) COWS-WMS (Python) UKCP Data lib UKCP Data lib geoplot geoplot chartplot chartplot Weather Generator Weather Generator Threshold Detector Threshold Detector Sun Grid Engine Sun Grid Engine cdat_lite, matplotlib, rpy, nappy cdat_lite, matplotlib, rpy, nappy User Interface Layer Application Layer Library Layer Processing Layer ddp-ps1 ddp-ps2 ddp-ps3 ddp-ui1 UI (php) geoserver (tomcat) spatialdb (postgres) ddp-app1 WMS (python) WPS (python) ddp-store1 SGE execd archive ddp-u2i UI (php) geoserver (tomcat) spatialdb (postgres) ddp-app2 WMS (python) WPS (python) ddp-store2 SGE execd archive ddp-ui3 UI (php) geoserver (tomcat) spatialdb (postgres) ddp-app3 WMS (python) WPS (python) ddp-store3 SGE execd archive acache 1 acache 2 acache 3 Master server and backup Physical servers Virtual Machines ddp-ps5 ddp-admin1 haproxy SGE master userdb (postgres) cache ddp-ps4 ddp-adminbak1 mirror state cachebak haproxy The UK Climate Projections 2009 are a set of probabilistic data products for the UK climate over the 21st century. The UKCP09 UI provides a rich, interactive user experience including map-based selections and outputs. The implementation integrates and extends Open Source GIS technologies including GeoServer, PostGIS, OpenLayers and Tilecache. Where necessary new components have been developed using the COWS framework. The UKCP-UI graphics page allows geospatial and probabilistic plots to be customised by the user. Requests for publication quality plots or the underlying data can then be sent to the WPS for processing before arriving in the user's download area. The UKCP09 UI was designed from the outset to be highly scalable and fault tolerant. The system is deployed as a cluster of XEN Virtual Machines, dividing the system into a set of functional VM types. These VMs are spread over multiple physical servers to provide both physical and virtual system failover. Load-balanced VM types are deployed in parallel allowing the system to scale up and down according to load, whereas the VMs managing state employ a separate hot-backup failover strategy", "label": "poster"}
{"text": "fBLS is a novel technique for detecting transiting planets, based fBLS is a novel technique for detecting transiting planets, based on the fast-folding algorithm [1], extensively used in pulsar on the fast-folding algorithm [1], extensively used in pulsar astronomy [2]. astronomy [2]. fBLS is efficient and scalable. It can substantially reduce the fBLS is efficient and scalable. It can substantially reduce the computation time required to search for transiting planets. For computation time required to search for transiting planets. For example, when applied example, when applied to the to the Kepler Kepler data, fBLS reduces the data, fBLS reduces the computation time by a factor of up to ~3000. computation time by a factor of up to ~3000. fBLS is well suited to the analysis of PLATO lightcurves. We fBLS is well suited to the analysis of PLATO lightcurves. We currently adapt fBLS and extend its operation to efficiently detect currently adapt fBLS and extend its operation to efficiently detect planets with varying transit duration and timing [4]. planets with varying transit duration and timing [4]. We used fBLS We used fBLS to detect small rocky transiting planets with to detect small rocky transiting planets with periods shorter than one day, a period range for which the periods shorter than one day, a period range for which the computation is extensive [3]. We have discovered five new planet computation is extensive [3]. We have discovered five new planet candidates (Shahaf et al., in prep.) candidates (Shahaf et al., in prep.) For a given lightcurve of measurements, fBLS simultaneously produces binned and phase-folded lightcurves for an array of \u2018sufficiently different\u2019 trial periods, with arithmetic operations. This procedure is conceptually similar to FFT. For comparison, a standard BLS implementation requires operations. For each folded lightcurve we compute the BLS statistic [5], producing a standard BLS periodogram. Demonstration: Kepler-78b Figure 1: fBLS periodogram of Kepler-78. The left panel is a grayscale diagram demonstrating the fast-folding algorithm output for a narrow frequency range centered around the periodogram peak. The fBLS periodogram appears on the Right panel, where the BLS scores were calculated for each of the fast-folded profiles. The central peak is highlighted in yellow. The required single-core computation time for the settings used in this example is ~10 sec. Ultra-short period (USP) planets are exoplanets with orbital periods shorter than one day, which tend to be terrestrial. Studies of these extreme systems can shed light on planet formation, star-planet and planet-planet interaction, and orbital evolution. A fast folding algorithm to produce BLS A fast folding algorithm to produce BLS periodograms in search for transiting planets periodograms in search for transiting planets R E L A T E D L I T E R A T U R E [1] Staelin D. H., 1969, Proceedings of the IEEE, 57, 724 [2] Morello V., et al., 2020,MNRAS, 497, 4654 [3] Winn J. N., Sanchis-Ojeda R., Rappaport S., 2018, New Astron. Rev., 83, 37 [4] Shahaf S., Mazeh T., Zucker S., Fabrycky D., 2021, MNRAS, 505, 1293 [5] Kov\u00e1cs G., Zucker S., Mazeh T., 2002, A&A, 391, 369 Sahar Shahaf (1, 11), Barak Zackay (1), Pascal Guterman (111), Tsevi Mazeh (11), Shay Zucker (1v) and Simchon Faigler (11). A F F I L I A T I O N S (1) Department of Particle Physics and Astrophysics, Weizmann Institute of Science, Rehovot 7610001, Israel. (11) School of Physics and Astronomy, Tel Aviv University, Tel Aviv, 6997801, Israel. (111) Aix Marseille University, CNRS, CNES, LAM, Marseille, France. (1v) Porter School of the Environment and Earth Sciences, Tel Aviv University, Tel Aviv, 6997801, Israel. C O N T A C T : sahar.shahaf@weizmann.ac.il Figure 2: Two examples of phase folded USP planet lightcurves with the same number of bins. Top\u2014a new USP candidate, detected by fBLS. Bottom\u2014 Kepler-78b, plotted for reference. Vertical axis range is identical. Despite the shall", "label": "poster"}
{"text": "Markers of Evolution in Rich Galaxy Clusters Elena Panko (panko.elena@gmail.com) and Sviatoslav Yemelianov, Anton Sirginava Department of Theoretical Physics and Astronomy, I. I. Mechnikov Odessa National University, Odessa, Ukraine Elena Panko The idea, formulation of the problem, input data, lgorithm, etc Sviatoslav Yemelianov soft, ~200 rich galaxy clusters data analysis, discussion Anton Sirginava Input data, ~200 rich galaxy clusters data analysis, discussion Abstract We detected statistically significant regular substructures in 2D distribution of galaxies in rich clusters with redshifts till to 0.15. Input data were extracted from \u201cThe Catalogue of Galaxy Clusters and Groups\u201d (Panko & Flin, 2006). Main type of substructures is linear elongated overdence regions in the cluster field. The direction of the linear substructure points usually to the nearest neighbor. In additional we found X- or Y- type regular substructures as well as short and/or compact chains. Bright galaxies in clusters are located in the regular substructures mainly and galaxies in the chains also show significant alignment along the chain. Founded peculiarities can be considered as a result of the formation of galaxy cluster at the intersection of DM filaments or filament-wall interaction. Input data format: The real 4200\"\uf0b44200\" field of PF 0381-1789 cluster from DSS-R (upper panel) and the CC map 4000\"\uf0b44000\". The background stars are present on the real frame. Weak galaxies on the frame are not visible. The reasons for present study: According to \uf04cCDM model computer simulations the distribution of galaxies in the clusters is the point index of the hot gas and DM distribution: Gas density tracing the cosmic web in a subvolume (12.5 Mpch-1 comoving horizontally, stacked over 25 Mpch-1 comoving along the line of sight) of the HORIZON- AGN simulation (Codis, Gavazzi, et al.,2015) Projected density map, nodes in filaments. GADGET-4 code (Wang et al., 2020) We supposed the ways of evolution in 2D distribution of galaxies are reflected as: O \uf05b I \uf05b C \uf05b cD (Struble & Rood,1982) or O \uf05b OL \uf05b IL \uf05b CL \uf05b C \uf05b cD (Panko, 2019) or O \uf05b O (X, Y, c) \uf05b I(X,Y, c) \uf05b IL \uf05b CL \uf05b C \uf05b cD (present study), were types of galaxy clusters: O \uf02d Open, I \uf02d Intermediate, C \uf02d Concentrated, cD \uf02d having cD galaxy, L \uf02d linear substructure, X,Y, c \uf02d other regular peculiarities (Panko, 2013, Panko et al., in prep.) Input Data: MRSS, the list of galaxies and PF Catalogue of galaxy clusters and groups The Muenster Red Sky Survey. It covers an area of about 5000 deg2 on the southern hemisphere. The catalogue includes 5.5 million galaxies and is complete till to rF=18m.3 (Ungruhe et al., 2003). It's a result of scanning of 217 plates of Southern Sky Atlas R (ESO) by PDS 2020GMplus and automated recognition of galaxies with careful control. White spot is the region around the SMC. PF Galaxy clusters (based in the MRSS (Panko & Flin, 2006). Our data set contains 460 rich galaxy clusters contain 100 and more members. MRSS Cluster data 0016-5711 0.1670739 -57.107367 940 2130600 88 31 48 907 617 0.32 117.4 13.02 13.72 15.05 97.4 0.41 22.8 Galaxies data 149-40043 59 2.75 5.30 3.85 0.31 24.0 16.56 16.53 0.136070 -57.054264 149-39501 21 2.15 4.26 2.51 0.49 178.0 17.98 17.95 0.139043 -57.081429 111-51504 394 6.14 12.73 7.33 0.51 16.5 14.81 14.77 0.140979 -57.240734 111-50854 111 4.09 7.88 4.37 0.54 19.1 16.35 16.32 0.143299 -57.250084 149-38602 36 3.27 7.23 2.99 0.72 34.9 17.53 17.50 0.143872 -56.993507 Cluster Cartography (CC) set allows to visualize the input data and to analyze the distribution of galaxies as well as to study the orientations of cluster members. CC allows automatically: to determine the level of the concentration to the cluster center; to detect linear substructures and other types of regular substructures, namely crosses, semicrosses. Curved chains and compact short dense stripes are need visual control. The shape of symbol corresponds to MRSS data, the size of symbols corresponds to ", "label": "poster"}
{"text": "Research Data Management Service Sustainability Tina Griffin, MLIS. Asst. Professor. University of Illinois Chicago. Chicago, IL 60612 Margaret Janz. Interpreter II. Great Parks of Hamilton County. Cincinnati, OH 54231 Introduction Libraries at high-level research and other academic institutions have been involved in research data management service (RDMS) for more than ten years. As the demand for these services has increased, libraries have adapted their service models. There have been several studies that have reviewed the \u201cstate of RDM services,\u201d but these have only provided a snapshot of activities at a given time. Research Data Management activities require support through infrastructure, personnel, time, and money. Previous studies address these topics individually, but there is little connection between RDMS data collected over time and are few longitudinal studies. These studies also do not address the necessary decisions and changes that must have been made to make RDMS sustainable over time. This study will attempt to fill that gap by updating the RDMS status to describe the current baseline, broadening the facets addressed so that details about sustainability can be highlighted, and presenting the data by cohort to help other institutions identify parallels to their RDMS. Methodology \u2022 A 62-question survey was distributed in the fall of 2020 for 6 weeks through data listservs and message boards (DataCure Google Group, Research Data Access and Preservation discussion forum, International Association for Social Science Information Service and Technology listserv, Digital Library Federation listserv, Research Data Alliance forums). Two reminders were sent, one at 3 weeks and one the day before close. \u2022 Questions asked about changes in service model, staffing and funding, accountability, and planning for research data management services since service inception. \u2022 The survey was reviewed by eight data librarians currently in the field, and edited for bias, errors, and clarity. A copy of he survey instrument can be downloaded here: https://go.library.uic.edu/RDMSUSurveyInstrument. \u2022 IRB at both authors\u2019 institutions reviewed the protocol and it was determined to be exempt. \u2022 The survey data was collected via Qualtrics Survey Software (Qualtrics, LLC. Provo, UT, USA. https://www.qualtrics.com/). \u2022 Received 118 responses. 70 responses were analyzed, including 32 which were partially complete. \u2022 Responses were excluded if: \u2022 did not contain any data (21) \u2022 only answered the question regarding service duration (9) \u2022 services were offered less than one year (16) \u2022 did not consent (2) \u2022 Personally identifying and some institutional demographic information was deleted before analysis, as per the informed consent agreement. Selected Results \u2013 Respondent Characteristics 13 14 31 12 1-3Y 3-5Y 5-10Y 10+Y Number of Respondents by Years offering RDMS 12 10 5 34 >7M 8-25M 25-50M unsure Respondents Library budget (Millions) Selected Results \u2013 Service profile Almost all respondents indicated that they have increased both technical and advisory services over time. Among all groups, the number of services offered ranged from two to fifteen. The average number of services offered from 1-3Y was 6.5, from 3- 5Y was about 10, cohort 5-10Y or 10+Y offered just under 8 each. Cohorts differ as to which services they offer. Number of Respondents offering RDS by Service level and cohort. Technical Only Advisory Only Both 1 1 3 2 2 1 2 1 3 2 4 6 5 4 4 1 1 1 2 2 2 1 1 2 1 3 4 5 Deidentification Analysis Offer resources Visualization Metadata Purchase Documentation Curation Preservation Citation Storage Finding Data Sharing Education/trai\u2026 Planning 1-3Y 2 1 1 1 4 2 6 8 6 4 8 2 9 8 3 2 1 1 1 1 3 3 3 2 2 3 5 2 6 2 3 9 Deidentification Analysis Offer resources Visualization Metadata Purchase Documentation Curation Preservation Citation Storage Finding Data Sharing Education/traini\u2026 Planning 3-5Y 1 4 4 6 7 7 4 10 11 6 14 13 13 11 11 2 1 1 5 2 4 2 4 9 1 ", "label": "poster"}
{"text": "sentinel-3A SLSTR \u2013 Early results The main objective of the Sentinel-3 SLSTR instrument is to maintain continuity with the ENVISAT (A)ATSR series of instruments within the European Copernicus programme. SLSTR will retrieve global coverage sea surface skin temperature (SSTskin) with zero bias and an uncertainty of \u00b1 0.3 K (1\u03c3) for a 5 x 5 degree latitude longitude area, having a temporal stability of 0.1 K/decade in support of Copernicus climate monitoring and operational Numerical Ocean/Weather Prediction (NOP/NWP) applications. In addition, SLSTR using a suite of visible and infrared radiance measurements, monitoring, ice surface temperature, cloud imagery, atmospheric aerosol, land, forestry and hydrology products in support of Copernicus serviceswill provide land surface temperature, active \ufb01re. This poster presentation presents initial results from the Sentinel-3A SLSTR as of May 25th 2016. C. Donlon, D. Smith (RAL), B. Berruti, J. Nieke and J. Frerick. Contact: Craig.Donlon@esa.int and for dave.smith@stfc.ac.uk further information. \u00e8About sentinel-3 Sea and Land Surface Temperature Radiometer \u00e8 A BIGGER PICTURE FOR COPERNICUS SLSTR Band L Centre [\u00b5m] \u0394L [\u00b5m] SNR [-] / Ne\u0394T [mK] Spatial Sampling Distance (SSD) [km] Function S1 0.555 0.02 20 0.5 Cloud screening, vegetation monitoring, aerosol S2 0.659 0.02 20 0.5 NDVI, vegetation monitoring, aerosol S3 0.865 0.02 20 0.5 NDVI, Cloud flagging, Pixel co- registration S4 1.375 0.015 20 0.5 Cirrus detection over land S5 1.61 0.06 20 0.5 Cloud clearing, Ice and snow, vegetation monitoring, S6 2.25 0.05 20 0.5 Vegetation State and Cloud Clearing S7 3.74 0.38 80 mK 1.0 SST, LST, Active Fire S8 10.95 0.9 50 mK 1.0 SST, LST, Active Fire S9 12 1.0 50 mK 1.0 SST, LST F1 3.74 0.38 < 1 K 1.0 Active Fire F2 10.95 0.9 < 0.5 K 1.0 Active Fire \u00e8Spectral channels \u00e8SLSTR Optical design \u00e7 The complete suite of AATSR and ATSR-2 spectral channels (0.55, 0.66, 0.85, 1.6, 3.7, 10.8 and 12 \u00b5m) is included in the SLSTR design in order to maintain continuity. Additional channels at 1.378 \u00b5m and 2.25 \u00b5m are included to enhance thin cirrus cloud detection. SLSTR has an additional capability to derive active \ufb01re measurements using an extended dynamic range of the 3.7 \u00b5m channel and dedicated optimized detectors at 10.8 \u00b5m that are capable of detecting \ufb01res at ~450 K without saturation. \u00e8 SLSTR uses two independent scan chains each including a separate scan mirror (scanning at a constant velocity of 180 rpm), an off-axis paraboloid mirror, and a fold mirror to focus measured radiance into the instrument Detector Assembly (DA). An innovative recombination \u201c\ufb02ip\u201d mirror alternately relays each of the scanned optical beams into a common \ufb01eld plane at the entrance of the DA where there is a cold baf\ufb02e. \u00e7 While more complex than the single scan system employed by the (A)ATSR instrument series, the SLSTR 3-mirror scan con\ufb01guration increases the instrument oblique view swath to ~750 km (centred at the SLSTR nadir point) and the nadir swath to~1400 km (offset in a westerly direction). The nadir swath is asymmetrical with respect to the nadir point to provide identical and contemporaneous coverage with OLCI ocean/land colour measurements. Visible and short-wave infrared detectors have a spatial resolution of 0.5 km on ground. Thermal infrared detectors have a spatial resolution of 1 km on ground. 05/04/2016 10:02 am. The first image from the Sentinel-3A SLSTR thermal-infrared channels at 1km spatial resolution reveals thermal signatures over a part of western Namibia and the South Atlantic Ocean. Cold water is seen along the Namibian coast upwelling from deeper waters. The Benguela current flows north along the west coast of South Africa driven by southeasterly winds, creating coastal upwelling. Many eddies and meanders are generated in this complex system and these small-scale features are captured beautifully. Over land, the distinct folds of desert dunes can be seen. In fact, further north, Gobabeb is the locati", "label": "poster"}
{"text": "25-27 June 2008 Madrid, Spain Knowledge production in evaluating rehabilitation of buildings \u2013 Areas of interest and biases Anandasivakumar Ekambaram 1, Andreas \u00d8kland 2 1SINTEF, 7031 Trondheim, Norway, siva@sintef.no 2SINTEF, 7031 Trondheim; Norway, Andreas.Okland@sintef.no Background \u2013 A structured literature review on evaluating rehabilitation of buildings Journals that are considered: \u2022 Building and environment \u2022 Cleaner Production \u2022 Construction Innovation \u2022 Construction Management and Economics \u2022 Energy and Buildings \u2022 Facility \u2022 International Journal of Project Management \u2022 Sustainability Selected period of publication: 2016-2018 Number of relevant articles (selected after the final round of study): 58 Preliminary results \u2013 Areas of interest Areas of interest that were found after the first round of categorization of the results: \u2022 Support for decision making: o Evaluation of potential improvement scenarios / options o Improving decision making \u2022 Simulation \u2022 User behavior \u2022 Life cycle approach: o Life Cycle assessment o Life Cycle Cost \u2022 Payback time \u2022 Policy These are key areas of interest. This categorization is based on the number of articles that focus on the areas of interest. At the early stage of the study, as each of the articles was read, all areas of interest (that is, what areas that each article focuses on) were noted. Biases \u2022 Number of citations of the articles can play a role in determining the areas of interest \u2022 Average number of citations per area of interest could lead to a dilemma / bias: \u2022 Articles published in 2016 could probably have more citations than the articles published in 2018 \u2022 Areas of interest could overlap each other \u2022 Choosing what area(s) of interest that an article focuses on could be subjective REZBUILD This study is connected to research project: The REZBUILD project (REfurbishment decision making platform through advanced technologies for near Zero energy BUILDing renovation) grows with the main aim of defining a collaborative refurbishment ecosystem focused on the existing residential building stock. \u2022 Awarded by the European Commission with a H2020 Programme Grant of \u20ac 6,996,128.25 \u2022 Total budget: \u20ac 9,038,208.75 \u2022 Duration: 4 years (Started in October 2017) REZBUILD will base its refurbishment ecosystem on the integration of cost-effective technologies, business models and life-cycles interaction. https://rezbuildproject.eu/ 20th European Conference on Knowledge Management | Portugal, 2019 An area of interest that was described in one article, and that article has larger number of citations An area of interest that was described in many articles, but those articles have lesser number of citations Versus", "label": "poster"}
{"text": "The public codes ASOHF and VORTEX for the post-processing of cosmological simulations David Vall\u00e9s-P\u00e9rez 1,\u2020 Susana Planelles 1,2 Vicent Quilis 1,2 1Departament d'Astronomia i Astrof\u00edsica, Universitat de Val\u00e8ncia 2Observatori Astron\u00f2mic, Universitat de Val\u00e8ncia \u2020david.valles-perez@uv.es ASOHF (Vall\u00e9s-P\u00e9rez, Planelles & Quilis, 2022) ASOHF is an adaptive spherical overdensity DM halo finder and galaxy finder. Among its main features, we can count: Haloes are detected from density peaks in configuration space. Dynamical information is subsequently used through several complementary unbinding processes. Physically motivated, self-consistent definition of substructures (see below). Possibility to look for galaxies within DM haloes (see below). Complete merger trees, robust to the loss of haloes in a number of snapshots. Outputs include lists of haloes with several (\u223c50) properties and, optionally, complete member particle lists. Python packages provided. Optimal scaling properties, \u2206twall \u223cNpart/ncores in shared-memory platforms (OMP) and low memory footprint. Does not require external, special libraries to be installed. Parallelisation (beyond OMP) Large (\u227350 Mpc) simulations with many (\u2273109) particles can benefit from the domain decompo- sition strategy, which is performed externally to the code. Different subdomains can be run con- currently or sequentially, and the different domain outputs are seamlessly merged afterwards. Substructure Substructures are delimited by their Jacobi radius, RJ, encompassing the region more bound to the satellite than to the host halo. This is usually a more restrictive definition than others based on the density profile alone. Galaxy finder Galaxies are looked for within DM (sub)haloes us- ing a variation of the SO method, and are finally characterised as fully independent objects (with different centre, bulk velocity, etc.). Galaxy ex- tents are delimited by density and density gradi- ent, in addition to phase space arguments. Learn more The paper The code The docs A&A 664 A42 github.com/dvallesp/ASOHF ASOHF.github.io 100 101 102 103 104 105 N( > M) 25 particles 100 particles ASOHF AHF ROCKSTAR SUBFIND Tinker+08 All haloes Subhaloes 101 102 103 104 105 106 Npart 109 1010 1011 1012 1013 1014 M (M ) 0.25 0.50 0.75 1.00 1.25 1.50 1.75 2.00 N( > M) / N( > M) vortex (Vall\u00e9s-P\u00e9rez, Planelles & Quilis, 2021a,b; Vall\u00e9s-P\u00e9rez et al. 2024) vortex is a post-processing code for performing several computationally-intensive analyses on the velocity fields of hydrodynamical simulations. While it was originally designed for block-based AMR simulations, it is now a general tool. Helmholtz-Hodge decomposition v(x) = vsol(x) | {z } Solenoidal part \u2207\u00b7vsol=0 + vcomp(x) | {z } Compressive part \u2207\u00d7vcomp=0 + vharm(x) | {z } Harmonic part (mostly irrelevant) The decomposition is straightforward for uniform grids, but much more complex for multi-resolution data, especially if O(N2) is to be avoided. We solve for a vector and a scalar potentials, such that: vcomp = \u2212\u2207\u03c6 vsol = \u2207\u00d7 A \u22072\u03c6 = \u2212\u2207\u00b7 v \u22072A = \u2212\u2207\u00d7 v Elliptic PDEs can be addressed by a combination of FFT techniques (base grid) and iterative solvers (e.g., SOR), so that overall the cost is \u2272O(N4/3). Multi-scale Reynolds decomposition v(x) = \u27e8v\u27e9L(x)(x) | {z } Bulk velocity field + \u03b4v(x) | {z } Turbulent velocity field The bulk velocity is obtained by performing a top- hat filtering with position-dependent width, \u27e8v\u27e9L(x)(x) = RRR |x\u2032\u2212x| mLEL); \u2018EQUIVOCAL\u2019 (dLEL> 200 but <1000); and \u2018NO\u2019 (dLEL>1000) in rat and/or rabbit study; (c) TP (true positive), FP (false positive), FN (false negative), TN (true negative); SENS, sensitivity [TP/(TP+FN)]; SPEC, specificity [TN/(TN+FP)]; ACC, accuracy [(TP+FN)/(TP+FP+FN+TN)]. Anatomical development Overview Computational synthesis and integration This poster does not represent EPA Policy i) assess qualitative performance of the predictive model; ii) set an exposure-based prediction of teratogenicity; iii) characterize sensitive response pathways; and iv) virtually reconstruct quantitative phenotypic response. Chemicals ranked by enumerated response Toxicity Prioritization index (ToxPi): \u2022 chart maps 753 ToxCast chemicals tested across 6 in vitro platforms; \u2022 slices indicate response (1) or no response (0) for each platform: blue - zebrafish platforms (2) yellow - ToxCast pathways (multiple) red - hESC (pluripotent H9 cells) green - mESC (differentiating J1 cells). Pyridaben (strong evidence) Captan (moderate evidence) Hexaconazole (weak evidence) 2,4-Dichlorophenoxy- acetic acid (false negative) Specific aims examples Human palatal closure (left) simulated in a virtual embryo (right). Running the simulation with ToxCast data for \u2018Captan\u2019 predicts a tipping point at 4 \u00b5M. Captan (+) EGF (-) TGF-beta Human HTTK model predicts exposure of a pregnant woman to Captan at 2.39 mg/kg/day would achieve a steady state of 4 \u00b5M in fetal plasma. example", "label": "poster"}
{"text": "De novo genome sequencing of Skeletonema marinoi and Surirella brebissonii Mats T\u00f6pel\u00b9*, Magnus Alm Rosenblad\u00b9, Ulrika Lind\u00b9, Susanna Gross\u00b2, Sandra Karlsten\u00b9, Jens Persson\u00b9, Mattias Backman\u00b9, Anna Godhe\u00b2, Anders Blomberg\u00b9 1. Department of Chemistry and Molecular Biology, University of Gothenburg 2. Department of Biology and Environmental Sciences, University of Gothenburg *mats@topel.se Introduction De novo whole genome sequencing of the two diatom species Suri- rella brebissonii (CCMP2919) and Skeletonema marinoi (GUMACC St54) are currently conducted as part of the Linnaeus Centre for Marine Evolutionary Biology (CeMEB) initiative at the University of Gothenburg. This work is part of the Infrastructure for Marine Genetic model Organisms (IMAGO) project, aimed at developing new marine model systems and provide genomic and genetic tools to study vital phenomena and components of coastal marine ecosystems. Protein translocation in diatoms A chloroplast\u2019s genome only encodes ~100 proteins, but the organ- elle requires many more proteins in order to perform its functions in the cell. Translocons at the Outer and Inner Chloroplast enve- lope membranes (TOC and TIC, respectively) are the two multi- protein complexes in plants, red- and green algae that enable chlo- roplasts to import these essential nuclear-encoded proteins. Diatom plastids, on the other hand, are surrounded by four mem- branes where the outermost is continuous with the endoplasmic reticulum (ER) [8]. The second membrane (known as the periplas- tid membrane [PPM]) is the remnant of the secondary endosymbiont\u2019s plasma membrane (proposed to be of red algal origin) [9]. The two innermost membranes are homologous to the outer and inner envelope membranes in plant plastids and are de- rived from the membranes surrounding the cyanobiont of primary plastids [10]. The identity of the TOC and TIC translocons in diatoms and most other chromalveolate organism groups (e.g brown algae, dinofla- gellates and apicomplexan parasites) is mainly unknown. How- ever, bioinformatics analyses of whole genome sequences from dia- toms has shown that these systems are also present in diatoms. Bullman et al. [11] reported the discovery of an Omp85 protein that is localized in the third outermost plastid membrane (homologous to the outer envelope membrane in plants) of the diatom Phaeodactylum tricornutum. To date, this Omp85 protein is the only reported putative member of the TOC complex in diatoms. Our phylogenetic analyses (including bacterial, plant and diatom sequences) reveals that the diatom sequences are of red algal origin and more specifically belongs to the Toc75 gene family. Unexpectedly long branches in the diatom part of the tree indicates a rapid, albeit even, evolu- tionary rate. This phenomenon has been reported on previously, but the significance of the phenomenon has not yet been thor- oughly investigated. Assembly statistics DNA libraries (insert size 150 and 3000 bp), of which one were gen- erated from an axenic culture, and one RNA library (300 bp) from Surirella brebissonii has been sequenced. One axenic 300 bp library from Skeletonema marinoi has been generated. Both genomes have been assembled using the CLC de novo assembler software package. Sequence reads where preprocessed using cutadapt [1] and the fastx toolkit [2] (for details see http://matstopel.se/notebook). Skeletonema Surirella Total nt sequenced (Gb) 33 46 Total input to assembly (Gb) 26 33 Assembly size (Mb) 49 136 Number of contigs (K) 53 244 Average coverage (x/cont) 443 207 N50 (bp) 1673 694 Average contig lenght (bp) 929 557 Longest contig (Kb) 506* 76 *Putative bacterial symbiont. Preliminary findings Organelles \u2212 The plastid of Surirella brebissonii contains a group II intron with an ORF, the first group II intron to be identified in dia- toms. Interestingly, the mitochondrial genome of S. brebissonii has lost the group II intron present in both Thalassiosira pseudonana and Phaeodactylum tricornutu", "label": "poster"}
{"text": "08-11 November 2021 Online Event Prediction of photoelectric effect log and facies classification in the Panoma gas field Felipe F. Melo CGG GeoSoftware (Formerly at PUC Rio) Contact: felipe146@hotmail.com 1) AIM Predict the photoelectric effect log on two wells and then perform facies classification. 2) Introduction Departing from seven wells in the training set, I impute missing values in the photoelectric effect log (PE) in one well and predict the PE log from two wells. Then, I aggregate these wells to the training data in order to perform facies classification. Distinct feature augmentation techniques are used in both log prediction and facies classification. I used the random forest algorithm for log prediction and the extreme gradient boosting for facies classification. Focusing on the generalization of the models, the hyperparameters were tuned with the nested and the leave two out cross validation, respectively. The well Churchman Bible is picked as test data, this well is chosen because it has all facies and a large number of samples related to facies of interest. 3) Dataset 4) Method 5) Prediction of photoelectric effect log 6) Facies Classification 7) Conclusions \u2022 The feature augmentation was successful in both prediction and classification. \u2022 The PE prediction score (72%) in the test well shows the good result of this approach. \u2022 The results for facies classification are acceptable because of the samples limitations, accuracy of 58%. \u2022 The accuracy of 86% on adjacent facies and 90% on BS, 57% on PS and 6% on D (critical facies) shows the effectiveness of the proposed approach. 9) References Dubois, M. K.; Bohling, G. C.; Chakrabarti, S. 2007. Comparison of four approaches to a rock facies classification problem. Computers & Geosciences, 33 (5), 599\u2013617. Hall, B. 2016a Facies classification using machine learning. The Leading Edge, 35, 906\u2013909. Hall, M.; Hall, B. 2017. Distributed collaborative prediction: Results of the machine learning contest. The Leading Edge, 36, 267\u2013269. 8) Acknowledgments I would like to acknowledge Brendon and Matt Hall, the participants of the SEG contest and the Swung community for push the knowledge and free software. This research has been benefited from knowledge and source codes shared by them. 10) Reproduce The codes used on this work are available at: https://github.com/ffigura/SBGf_ ML_gas/ Figure 1 \u2013 Distribution of facies for each well, the well names are shown over each plot. The last panel shows the distribution of all facies. Figure 2 \u2013 Cross-plots from the well logs colored with facies classification. Figure 3 \u2013 Well logs and facies from the well Nolan. Figure 4 \u2013 Feature augmentation for well Nolan. Figure 5 \u2013 Prediction results. a) Feature importance for the test set. b) True and predicted logs from the well Nolan, this well is part of the training set. c) True and predicted logs from the test set, well Churchman Bible. Figure 7 \u2013 Confusion matrix. The facies as BS, PS and D are more critical in this work. The well Churchman Bible is used as test dataset, i.e., the quality of the regressor and of the classifier will be evaluated on this well. All other nine wells are used as training dataset for facies classification. In the first part, the photoelectric effect (PE) log is imputed for the well Recruit F9 (12 missing samples) and computed for the wells Alexander D and Kimzey A using the Random Forest regressor. Before log prediction, I perform feature augmentation. In this case, it adds non-linearities computing quadratic expansion and by considering all second order interaction terms and applies a low pass filter with the 1D discrete wavelet transform in the logs. Therefore, the training set moves from six to twenty features before estimate the PE logs. The logs NM_N and RELPOS are not used in feature augmentation because it would make no geophysical sense. After prediction of the PE logs into the two missing wells, these wells are grouped with the seven wells used as trai", "label": "poster"}
{"text": "activity consulting / coordination / event Activities & Services A visual walk through 2019-05-05 | Andrea Scharnhorst - Femmy Admiraal - Dirk Roorda | DANS Austria (AT) Belgium (BE) Croatia (HR) Cyprus (CY) Denmark (DK) France (FR) Germany (DE) Greece (GR) Ireland (IE) Italy (IT) Luxembourg (LU) Netherlands (NL) Poland (PL) Portugal (PT) Serbia (RS) Slovenia (SI) activity resource creation / software development service access to resources / data hosting / processing / support uncert ain 15 a/cons ulting 17 a/event 52 a/resource creation 29 a/software development 21 s/access to resources 60 s/data hosting 15 s/processing service 25 s/support service 21 a/DARIAH coordination 34 DARIAH (in-kind) contributions", "label": "poster"}
{"text": "Simple tool quantifying sediment resuspension effects on marine organic carbon storage A rapid and efficient solution for integrating sediment heterogeneity in resuspension and C storage assessments. Global trawling CO2 footprint estimations3 lack \u2022 measurements of resuspension effect on org. C mineralization rates4 \u2022 accountancy for spatial variation of sediment types/ habitats5 Seafloor plays pivotal role for Earth\u2019s climate by storing organic carbon long-term.1 Resuspension enhances mineralisation of stored organic carbon to CO2.2 Ines Bartl Tegan Evans Jenny Hillman Simon Thrush Institute of Marine Science, The University of Auckland, Auckland 1142, New Zealand ines.bartl@auckland.ac.nz Acknowledgments: This research was funded by the University of Auckland, the George Mason Centre for the Environment, the Ministry of Business, Innovation and Employment (UOAX2307), and the Oceans of Change Project. We thank Stefano Schenone, Sam Ladewig, Simon Thomas, Alessandra Valim, Li Yeoh, Keshav Chandran, Gemma Cunnington, Eliana Ferreti, Caitlin Grosvenor, Paul Caiger, Andrew Reid, Sophie Thomson, and Alanta Loucks for their assistance during the field campaigns, with special thanks to Brady Doak for both his professional support and his hospitality during the cruise. References: 1 Bianchi, T. S., Cui, X., Blair, et al. (2018). Organic Geochemistry, 115, 138\u2013155. https://doi.org/10.1016/J.ORGGEOCHEM.2017.09.008 2 St\u00e5hlberg, C., Bastviken, D., Svensson, B. H., & Rahm, L. (2006). Estuarine, Coastal and Shelf Science, 70(1\u20132), 317\u2013325. https://doi.org/10.1016/J.ECSS.2006.06.0224 3 Sala, E., Mayorga, J., Bradley, D., et al. (2021). Nature, 592. https://doi.org/10.1038/s41586-021-03371-z 4 Hiddink, J. G., van de Velde, S. J., McConnaughey, R. A., et al. (2023). Nature 2023 617:7960, 617(7960), E1\u2013E2. https://doi.org/10.1038/s41586-023-06014-7 5 Epstein, G., Middelburg, J. J., Hawkins, J. P., et al. (2022). In Global Change Biology (Vol. 28, Issue 9, pp. 2875\u20132894). https://doi.org/10.1111/gcb.161056 6 J\u00f8rgensen, B. B., Wenzh\u00f6fer, F., Egger, M., & Glud, R. N. (2022).. Earth-Science Reviews, 228, 103987. https://doi.org/10.1016/J.EARSCIREV.2022.103987 7 Sawyer, C. N., McCarty, P. L., & Parkin, G. F. (2003). Chemistry for Environmental Engineering and Science. 5th (edn) McGraw-Hill Inc. New York, 1\u2013752. The Resuspension Assay What\u2019s next? Identifying vulnerability of Hauraki Gulf sediments to demersal fishing. Simple \uf0e0 based on BOD method7 Rapid \uf0e0 short incubations of 3-5 hrs Efficient \uf0e0 7-8 sites per day in 50 km radius Affordable \uf0e0 inexpensive equipment https://www.usgs.gov/media/images/conceptual-drawing-ocean-trawling", "label": "poster"}
{"text": "Characterizing pathways of exposure for risk-based chemical prioritization Data streams Large public inventories, reporting chemical use and/or occurrence: \u2022 ACToR USEdb [3]: manually-curated pathways database (2015) \u2022 CompTox Chemicals Dashboard (CCD) chemical lists [4] (https://comptox.epa.gov/dashboard/chemical-lists) \u2022 Chemical Data Reporting 2016-2020 [5] \u2022 CPDat (Chemical & Products Database) [6-11] via ChemExpo (see poster P284/abstract 3795) \u2022 Chemical-Product Composition data \u2022 Functional Use categories \u2022 Chemical List Presence (curated tags) Data streams include 62,692 unique DSSTox Substance IDs Figure 2. Data streams for food-only chemicals. Left panels: Specific CCD lists. Upper/lower panels: Chemicals with multiple/single data streams. Many chemicals have info only from CCD lists of food volatiles or food contact substances. https://comptox.epa.gov /dashboard/chemical- lists Case Study: Food-Only Chemicals For references or copy of poster: Scan QR code or https://github.com/carolinering/pathwaysSOT2023 Contact: ring.caroline@epa.gov Caroline L. Ring1; Paul M. Kruse1,2; John F. Wambaugh1; Kristin K. Isaacs1 1 US EPA Center for Computational Toxicology and Exposure (Research Triangle Park, NC, USA) 2 Oak Ridge Institute for Science and Education (Oak Ridge, TN, USA) Pathway classifications Figure 1. Heatmap of pathway classifications (left panel) and data stream sources (right panel) for 62,692 unique DTXSIDs. Overview Manual mapping of chemical exposure data to broad exposure pathway categories to categorize 62,692 chemicals by exposure pathway Methods Scientific Impact & Potential Applications \u2022 Pathways can be used to inform rapid exposure models for use in risk-based chemical prioritization [1], e.g.: \u2022 as a training set for automated read-across of exposure pathways based on chemical structure \u2022 as features (predictor variables) for machine-learning models of exposure [2] \uf0d8Consumer o Fragrance o Personal care o Cosmetic \uf0d8Pesticide o active o inert \uf0d8Industrial \uf0d8Pharmaceutical \uf0d8Food/Dietary \uf0d8Other o Flame retardant o Tobacco o Colorant o Commercial o Agricultural \uf0a7 Fertilizer o Biocide \uf0a7 Herbicide \uf0a7 Antimicrobial Chemical may be positive, negative, or unclassified (no data, NA) for each pathway. Negative = ChemExpo Chemical List Presence tags \"prohibited\", \"restricted\", \"not used\", \"non_food_use\", \"nondetect\" Classifications from each data stream may disagree. Here: \u2022 Any positive = positive overall. \u2022 No positive & any negative = negative overall. \u2022 All NA = NA overall. 6583 chemicals positive for the Food pathway and negative or NA for all other pathways Case Study Summary \u2022 Transparent, granular sourcing for pathway categorization \u2022 Majority of food-only chemicals rely on data from 1-2 lists \u2022 Food-only chemical classes are consistent with source lists (e.g. flavors) Figure 3. ClassyFire classifications for food-only chemicals. Colored rings: # of food-only chemicals in each superclass (inner ring) and class (outer ring, labels). Most frequent classes: Prenol lipids; Fatty acyls; Organooxygen compounds. Visualized using ClassyFire [12] & treecompareR package (see poster P160/abstract 3675). Fatty acyls Prenol lipids Organooxygen cpds.", "label": "poster"}
{"text": "Understanding Lithium Extraction Through Social Life Cycle Assessment in the American Context: A Critical Review Megan Jermak, Sarah Cribb, Joseph Bozeman III, PhD CEM Georgia Institute of Technology | Social Equity and Environmental Engineering Lab Beno\u00eet, C. et al. (2021). Guidelines for Social Life Cycle Assessment of Products and Organizations 2020. Life Cycle Initiative. United Nations Environmental Programme. www.lifecycleinitiative.org/wp-content/uploads/2021/01/Guidelines-for-Social-Life-Cycle-Assessment-of-Products-and- Organizations-2020-22.1.21sml.pdf. Beno\u00eet, C. et al. (2009). The Guidelines for Social Life Cycle Assessment of products: Just in time! The International Journal of Life Cycle Assessment, vol. 15, no. 2, 21 Jan. 2010, pp. 156\u201316., https://doi.org/10.1007/s11367-009-0147-8. Riofrancos, T. (2022). The Security\u2013Sustainability Nexus: Lithium Onshoring in the Global North. Global Environmental Politics, 23(1), 1\u201322. https://doi.org/10.1162/glep_a_00668 Jaskula, B. W. (2024). Lithium. In U.S. Geological Survey mineral commodity summaries 2024. U.S. Geological Survey. https://pubs.usgs.gov/periodicals/mcs2024/mcs2024-lithium.pdf Mancini, L., & Sala, S. (2018). Social impact assessment in the mining sector: Review and comparison of indicators frameworks. Resources Policy, 57(57), 98\u2013111. ScienceDirect. https://doi.org/10.1016/j.resourpol.2018.02.002 Chhipi-Shrestha, G. K., Hewage, K., & Sadiq, R. (2014). \u201cSocializing\u201d sustainability: a critical review on current development status of social life cycle impact assessment method. Clean Technologies and Environmental Policy, 17(3), 579\u2013596. https://doi.org/10.1007/s10098-014-0841-5 Grubert, E. (2016). Rigor in social life cycle assessment: improving the scientific grounding of SLCA. The International Journal of Life Cycle Assessment, 23(3), 481\u2013 491. https://doi.org/10.1007/s11367-016-1117-6 Ramirez, P. K. S., Petti, L., Haberland, N. T., & Ugaya, C. M. L. (2014). Subcategory assessment method for social life cycle assessment. Part 1: methodological framework. The International Journal of Life Cycle Assessment, 19(8), 1515\u20131523. https://doi.org/10.1007/s11367-014-0761-y Bozeman, J. et al. (2022). A path toward systemic equity in life cycle assessment and decision-making: Standardizing sociodemographic data practices. Environmental Engineering Science, vol. 39, no. 9, 1 pp. 759\u2013769. https://doi.org/10.1089/ees.2021.0375. Social Life Cycle Application Conclusion and Recommendations Acknowledgements In this critical review, lithium mining is examined under the context of its extraction phase, examining how social and environmental outcomes in foreign mining projects may be echoed in new American mining endeavors. Industrial ecology tools, such as Social Life Cycle Assessments (SLCAs), can be utilized to draw comparisons of unit operations across varying countries and contexts. As part of the guidelines established by the United Nations Environmental Programme (UNEP) for implementing SLCAs, two Life Cycle Inventories (LCI) were conducted analyzing the social impacts of lithium mining operations. One LCI addressed lithium mines currently operating within South America (SA), while the other LCI investigated data on a Thacker Pass, a proposed mine within the United States (US). Social Life Cycle Assessment (SLCA) is a tool developed by the United Nations Environment Programme/Society for Environmental Toxicology and Chemistry (UNEP/SETAC) for the analysis of social impacts associated with a product\u2019s life cycle from cradle to grave (UNEP, 2009). Although SLCA has evolved significantly in recent years, limited standardization of procedures has restricted its use in the US. Meanwhile, the U.S. is rapidly expanding its lithium mining industry to meet electric vehicle (EV) demand and stabilize lithium supply chains (Riofrancos, 2022). While US mining companies posit American mines as safer and more sustainable than those in the global South, storied negative social implicati", "label": "poster"}
{"text": "Capabilities, contents, and use cases of the Outer Planets Unified Search (OPUS) from the PDS RMS Node Megan R.K. Seritan, M.S. Tiscareno, R.S. French, M.R. Showalter, M.K. Gordon, Y.-J. Chang, D.J. Stopp, J.N. Spitale, M.J.T. Mace, E.R. Simpson | SETI Institute\u2014Mountain View, CA The Planetary Data System (PDS) is NASA\u2019s scientifically-guided archive for planetary science: The Ring-Moon Systems (RMS) Node is a PDS Discipline Node located at the SETI Institute in Mountain View, CA: The Outer Planets Unified Search (OPUS) is a cross- mission, cross-instrument data search tool: What is PDS? What is RMS? What is OPUS? OPUS Support of Cross-Discipline, Cross-Instrument Search What\u2019s New! \u2022 Users can now search using detailed geometric metadata for all Galileo SSI images Example 2 of RMS-generated metadata: Geometric metadata Galileo SSI metadata Cassini UVIS HDAC Cassini UVIS HSP Cassini UVIS EUV Cassini CIRS Cassini CIRS Cassini ISS Different Filters Cassini VIMS New Horizons MVIC OPUS provides rich, consistent metadata \u2022 OPUS now includes New Horizons LORRI and MVIC data through the end of 2020 New Horizons new data \u2022 New previews and diagrams are available for browsing and downloading \u2022 These provide at-a-glance identification info for these non-image observations \u2022 Four different Voyager instruments are supported: PPS, UVS, and RSS (occultation) & ISS (reflectance) Previews show the occultation profile itself\u2026 \u2026while diagrams show the source\u2019s path through the field of view. \u2022 OPUS now supports PDS4 datasets! \u2022 Metadata still consistent and accurate! Related concepts with different names, such as \u201cvolume\u201d (PDS3) and \u201cbundle\u201d (PDS4), are combined \u2022 Earth-based Uranus ring & atmosphere stellar occultations from 1977-2002 is the first PDS4-only data set in OPUS Support for PDS4 OPUS geometric search categories 0.5 0.6 0.7 0.8 Hubble WCF3 F689M Galileo SSI Red Voyager ISS Orange Cassini ISS Red 0.65-0.72 \u03bcm 0.62-0.73 \u03bcm 0.59-0.64 \u03bcm 0.57-0.72 \u03bcm wavelength (\u03bcm) Example 1 of RMS-generated metadata: Consistent wavelength information Example 3 of RMS-generated metadata: Information-rich search results \u2022 Archival datasets, especially in PDS3, were not designed with cross-discipline, cross- instrument search as a goal \u2022 Because of this, the metadata in these archival datasets that would make cross- discipline, cross-instrument search possible is usually incomplete or missing, at no fault of the data provider \u2022 The major benefit of OPUS is that RMS creates consistent supplemental metadata fields to facilitate cross-mission, cross-discipline search \u2022 See the following examples of RMS-generated metadata that allow cross-discipline, cross- instrument search: \u2022 OPUS makes wavelength into a standardized attribute \u2022 This feature addresses the issue of filters covering similar, but not identical, wavelength ranges and having various names \u2022 For example: \u2022 When wavelength is a standardized attribute, users can find related observations that may not have been found when looking at archived metadata alone \u2022 OPUS geometric metadata identifies every body and ring inside the field of view of an image \u2022 This metadata is derived by densely sampling the field of view and reporting the full range of values for each geometric parameter \u2022 These attributes are available in a consistent way for every supported dataset \u2022 RMS-generated thumbnails are a visual type of metadata to make cross-discipline, cross- instrument search easier \u2022 Some sets of thumbnails use color-coding to indicate wavelength/filter type: \u2022 A federated structure of six discipline-specific nodes and two support nodes \u2022 Run by scientists who bridge the data community and the research community \u2022 Provides expert curation and peer review of datasets \u2022 The Node\u2019s emphasis is on datasets in which rings, moons, and/or their primary bodies are viewed as a system \u2022 We focus on placing individual data products in context \u2022 In practice, this works out to: o Jupiter, Saturn, Uranus, Neptune, Pluto, &", "label": "poster"}
{"text": "Management and Uncertainties of Severe Accidents L.E. Herranz (CIEMAT), S. Paci (UNIPI) MUSA was founded in HORIZON 2020 EURATOM NFRP-2018 call on \u201cSafety assessments to improve Accident Management strategies for Generation II and III reactors\u201d On June 15th, 2018 MUSA obtains the NUGENIA label that recognizes the excellence of the project Numerical tools are widely used to assess the Nuclear Power Plants (NPP) behaviour during postulated Severe Accidents (SA). Considering the complexity of the processes taking place during a SA and the inherent nature of numerical codes (numerics, spatial discretization, etc.), it is mandatory to quantify their embedded uncertainties taking into account the latest developments in methods and algorithms as well as the availability of computing resources. Mathematical tools for quantification of code uncertainties and sensitivities have been under development for many years, with a huge accumulated experience in performing Uncertainty Quantifications (UQ) with Best Estimate (BE) system codes, partly because of new requirements in regulations of some countries as part of the NPPs licensing processes. This is so far not the case for SA codes and only a few investigations have been focused on SA and UQ. MUSA has an \u201cinnovative research agenda\u201d in order to move beyond the state-of-the-art regarding the predictive capability of SA analysis codes by combining them with the best available or improved UQ tools. By doing so, not only the prediction of timing for the failure of safety barriers and of radiological Source Term (ST) will be possible, but also the quantification of the uncertainty bands of selected analysis results, considering any relevant source of uncertainty, will be provided. Objective of the MUSA project Assess the capability of SA codes when modelling reactor/ SFP accident scenarios of GEN II, GEN III designs Identification of UQ methodologies to be employed, with emphasis on the effect of both existing and innovative SAM measures on the accident progression, particularly those related to the ST mitigation Determination of the state-of-the-art prediction capability of SA codes regarding the ST that potentially may be released to the external environment, and to the quantification of the associated code\u2019s uncertainties applied to SA sequences in NPPs and SFPs MUSA Work Packages WP WP MUSA COordination (MUCO), coordinated by CIEMAT WP2 Identification & Quantification of Uncertainty Sources (IQUS), coordinated by GRS WP3 Review of Uncertainty Quantification Methods (RUQM), coordinated by KIT WP4 Application of Uncertainty Quantification Methods against Integral Experiments (AUQMIE) by ENEA WP5 Uncertainty Quantification in the Analysis and Management of Reactor Accidents (UQAMRA) by JRC WP6 Uncertainty Quantification and Innovative Management of SFP Accidents (IMSFP) by IRSN WP7 COmmunication & REsults DISsemination (COREDIS) coordinated by UNIPI Dissemination of Knowledge Special attention for knowledge transfer towards young researchers and Masters/PhD students Production of public learning modules to be published in the MUSA open website. Mobility programme under which university students and young researchers go to internship programmes Production of a lecture on \u201cUncertainty Quantification in Severe Accident Analyses\u201d for the different international Courses that might be given on Severe Accidents and/or on \"uncertainties\" MUSA Education activities will be carried out in a close collaboration with the ENEN Network Perspectives MUSA will mean a better exploitation of research previously performed within the EU framework Over the years, reliable and experienced teams of modellers and analytical teams have been built-up, and MUSA is an unique opportunity to achieve real feedback among them In addition, MUSA encourages cooperation in research, innovation and young generation\u2019s formation Finally, MUSA will be an open results project for its importance on forthcoming SA analyses CONTACT: Pr", "label": "poster"}
{"text": "Urban Growth: Effects on urban green spaces and implications for planning and policy Marta Vallejo, MACS, Heriot-Watt University Supervisor: David W. Corne How to apply a Genetic Algorithm to a Sequential Planning Problem GREEN AREAS GENETIC ALGORITHM STATISTICAL DATA Metric: POPULATION SATISFACTION PROBLEM MODEL PROCEDURE RESULTS Agent-Based Modelling \u2013 Cellular Automata POLICIES & GUIDELINES Description: Cellular Automata model a city and its surroundings. Each cell has an ecological random value. The city growth has a negative effect on these values. The city is populated with a set of agents which represent families and are modelled by the use of an Agent-Based approach. E-mail: mv59@hw.ac.uk PGR Student Poster Day - 23rd August 2012 Objective: Distributing a set of green areas throughout the city and achieving the maximum satisfaction from the inhabitants of the city. An agent is satisficed if it lives close enough of one of these areas. GA should deal with future uncertainty: need the support of external tools (Statistical Data) Experiments still in progress. Preliminary data indicates a positive improvement in the satisfaction of the population using a GA-Statistical approach. Next steps: \u00b7 Include new metrics like preserve most valuable ecological areas \u00b7 Increase the complexity of the model to get closer to real-world scenarios \u00b7 Validate the strategy followed by the comparison with other approaches commonly used for sequential planning problems like Reinforcement Learning.", "label": "poster"}
{"text": "Innovative Research for a Sustainable Future www.epa.gov/research ORCID: 0000-0002-4024-534X John Wambaugh l wambaugh.john@epa.gov l 919-451-5400 Product Deformulation to Identify Exposure Pathways for ToxCast Chemicals John Wambaugh1, Alice Yau2, Katherine Phillips3,4, Kristin A. Favela2, Chantel Nicolas1,4, Derya Biryol3,4, Christopher Grulke1,5, Ann M. Richard1, Paul Price3, Antony Williams1, Kristin Isaacs3, Russell Thomas1 National Center for Computational Toxicology1 and National Exposure Research Laboratory3, U.S. Environmental Protection Agency, Office of Research and Development Southwest Research Institute2, Oak Ridge Institute for Science and Education4, Lockheed Martin5 Abstract Introduction Results Estrogen Actives and Flame Retardants Summary High throughput screening (HTS) data that characterize chemically induced biological activity have been generated for thousands of chemicals by the US interagency Tox21 and the US EPA ToxCast programs. In many cases there are no data available for comparing bioactivity from HTS with relevant human exposures. The EPA\u2019s ExpoCast program is developing high-throughput approaches to generate the needed exposure estimates using existing databases and new, high-throughput measurements. The exposure pathway (i.e., the route of chemical from manufacture to human intake) significantly impacts the level of exposure. The presence, concentration, and formulation of chemicals in consumer products and articles of commerce (e.g., clothing) can therefore provide critical information for estimating risk. We have found that there are only limited data available on the chemical constituents (e.g., flame retardants, plasticizers) within most articles of commerce. Furthermore, the presence of some chemicals in otherwise well characterized products may be due to product packaging. We are analyzing sample consumer products using 2D gas chromatograph (GC) x GC Time of Flight Mass Spectrometry (GCxGCTOF/MS), which is suited for forensic investigation of chemicals in complex matrices (including toys, cleaners, and food). In parallel, we are working to create a reference library of retention times and spectral information for the entire Tox21 chemical library. In an examination of five plastic children\u2019s toys, as many as 114 and as few as 56 chemicals were identified in each toy, with between 0 and 40 unidentified chemicals in each. Putative endocrine disrupter, Bisphenol A (BPA), was identified as present in a product marked \u201cBPA free\u201d. Information on chemical constituents of products, while only a prerequisite to actual exposure, provides heuristics for estimating likely human exposure pathways for thousands of chemicals. Methods Example: Chromatograms for Baby Toys [solvent tail] is is is is is s s s s s s s is [solvent tail] is is is is is s s s s s s s is [Column bleed] [solvent tail] [Column bleed] is is is is is is s s s s s s s [solvent tail] [Column bleed] is is is is is is s s s s s s s [solvent tail] [Column bleed] is is is is is is s s s s s s s [solvent tail] [Column bleed] is is is is is is s s s s s s s [solvent tail] [Column bleed] is is is is is is s s s s s s s [solvent tail] [Column bleed] is is is is is is s s s s s s s [solvent tail] [Column bleed] is is is is is is s s s s s s s [solvent tail] [Column bleed] is is is is is is s s s s s s s [solvent tail] [Column bleed] is is is is is is s s s s s s s [solvent tail] [Column bleed] is is is is is is s s s s s s s is = internal standard s = surrogate Product 1 Product 2 Product 3 Product 4 Product 5 Retention Time First Dimension (s) Retention Time Second Dimension (s) 100x 10x 1x DCM Dilution \u2022 Southwest Research Institute conducted analytical chemistry screening for large numbers of chemicals in consumer products and articles of commerce \u2022 Five sample products were arbitrarily selected from each of twenty different categories \u2022 Products were analyzed using two dimensional gas chromatograph (GC) x GC Time of Flight Mass Spectrometry", "label": "poster"}
{"text": "Kelle Cruz (CUNY, NY, USA), William J. Cooper (U. of Hertfordshire, UK), David R. Rodriguez (STScI, MD, USA), Sherelyn Alejandro (CUNY, NY, USA), Ella Hort (Pomona College, CA, USA), Cl\u00e9mence Fontanive (U. of Bern, Switz.), Niall Whiteford (American Museum of Natural History, NY, USA) The SIMPLE Archive project \u2014 the Substellar and IMaged PLanet Explorer Archive of Complex Objects \u2014 is an endeavor to create a collaboratively maintained database of low-mass stars, brown dwarfs, and directly-imaged planetary mass objects using GitHub, Python, and SQL. Contribute The vision for SIMPLE is that anyone can contribute data using a typical GitHub workflow. The chart below illustrates the workflow from inserting new data to a local database instance via Python, review of database modifications in GitHub, and then publishing them to the website. Please join the #simple-db-dev channel in the Astropy Slack workspace for data contribution and development discussion. Develop \u2022Work on local instance \u2022Export to JSON \u2022Commit to branch Review \u2022Issue pull request \u2022Run validation tests \u2022Merge changes Publish \u2022Run GitHub actions \u2022Load DB from JSON \u2022Deploy to website The SIMPLE Archive http://simple-bd-archive.org/ A collaboratively-curated database and website of low mass stars, brown dwarfs, and exoplanets Holdings The SIMPLE Archive currently contains over 3,000 sources, including directly imaged planets and UCDs with spectral types M7 and later. SIMPLE-AstroDB/SIMPLE-db/ SIMPLE-AstroDB/SIMPLE-web/ #simple-db-dev on astropy.slack.com/ http://joinslack.astropy.org/ Explore and Search \u2022 Website: search by object name, coordinates, or full text. \u2022 Python: SQL searches using astrodbkit2. This material is based upon work supported by the National Science Foundation under Grant No. AST-1909837. \u2022 DBBrowser: Browse data using a GUI and/or SQL. For these 3,000 sources, it contains: \u2022 11,638 photometry measurements \u2022 4,897 proper motion measurements \u2022 2,628 parallax measurements \u2022 1,404 spectra", "label": "poster"}
{"text": "https://zarr.dev zarr-developers @zarr_dev bioimaging distributed and cloud storage geospatial chunked storage allows parallelized access and computation data science built-in compression The Zarr specification and implementations are governed by an open process. Specification changes are suggested via Zarr enhancement proposals (ZEP). Those are reviewed and voted on by the Zarr Implementors Council (ZIC) and Zarr Steering Council (ZSC). https://zarr.dev/zeps Governance process Broad Compatibility, based on a Common Specification Funding provided by the Zarr is a Sponsored Project of Confocal imaging of mouse blastocysts Skin Layers Dermis and Epidermis Neuroglancer Napari webKnossos Atmospheric Conditions from the Coupled Model Intercomparison Project Phase 6 (CMIP6) Usage Examples Example of a Bioimaging Dataset Streamed with Zarr Chunking and Compression compatible with NEUROGLANCER INTERACTIVE NOTEBOOK https://bit.ly/3QsmI1M compatible with Chunked, Compressed N-Dimensional Arrays Josh Moore German BioImaging e.V. (NFDI4BIOIMAGE) @notjustmoore josh@openmicroscopy.org", "label": "poster"}
{"text": "a School of Civil, Environmental and Mining Engineering, University of Adelaide, SA, Australia b Hydrology and Atmospheric Sciences, University of Arizona, Arizona, USAFenner School of Environment, Australian National University, Canberra, SA, Australia d College of Science and Engineering, Flinders University, SA, Australia e Bren School of Environmental Science & Management, UC Santa Barbara, CA, USA Virtual Hydrological Laboratories: Developing the next generation of conceptual models to support decision-making under change Mark Thyer (a), Hoshin Gupta (b), Seth Westra(a), David McInerney(a), Holger Maier(a), Dmitri Kavetski(a), Tony Jakeman(c), Barry Croke(c), Craig Simmons(d), Margaret Shanafield(d) , Daniel Partington(d), Christina Tague(e) Lead Author Email: mark.thyer@adelaide.edu.au Presenting Author Email: Tony.Jakeman@anu.edu.au 1. Conceptual models commonly used in practice, but may provide poor predictions of future hydrological change J4. Hydrologic non-stationarity and extrapolating models to predict the future \u2022 Conceptual models (see Figure 1) are the most common type of surface hydrological model used for decision-making (Peel and McMahon, 2020) \u2022 Due to suitable predictive performance, ease of use and computational speed which facilitates scenario/sensitivity/uncertainty analysis \u2022 They have significant limitations in their ability to capture the wide range of hydrological changes (see Figure 2) (Partington et al, 2022, Fowler, et al, 2022) Figure 1: \u2018End-Member\u2019 types on the spectrum of hydrological models 2. Developing next generation of conceputal models: Hydrological Lines of Evidence (HLE) Figure 2: Range of Drivers of Hydrological Change Robustness in terms of (1) Predictive Ability: accurate predictions of observations (2) Hydrological Fidelity: Capture key processes under change 3. Emerging HLE: Virtual Hydrological Laboratory 4. Evaluation of hydrological lines of evidence to provide conceptual models robust to future change Key Question(s): Can the HLE evaluate for \u201crobustness\u201d for 1. Catchments of practically relevant size (100\u2019s to 10,000\u2019s km2) 2. Catchments with diverse range of different properties 3. Wide range of process/predictions (not just streamflow, but also ET, soil moisture etc) 4. Using real observed data 5. Robustness to \u201cSignificant\u201d Change \u2013 see Table 1 (below) for different approaches to evaluating change 5. Unique Strengths of Virtual Hydrological Laboratory to Accelerate Development of Conceptual Models 1. Conceptual model development informed by wide range of processes In a virtual catchment all hydrological components can be observed (albeit virtually), and conceptual models can be subjected to a higher level of scrutiny than current observational datasets allow. 2. Enables the use of controlled hydrological change experiments Ability to systematically change climate and land cover/use characteristics provides opportunity to undertake hydrological change experiments and pro-actively evaluate CMs on a wide range of future hydrological change scenarios that are outside the envelope of observations. 3. Integrate Multiple Hydrological Lines of Evidence A VHL provides the opportunity to integrate multiple lines of evidence (Figure 4) thereby overcoming their respective strengths and weaknesses to build the next generation of conceptual models 6. Call to Action Predictive skill in hydrology is confronted by rapid and multi-faceted change. Our current suite of conceptual models have limited ability to deal with change. New thinking will be needed as hydrological systems are being pushed outside the envelope of historical experience \u201cVirtual Hydrological Laboratories\u201d provide a unique opportunity to 1. Undertake \u201ccontrolled experiments\u201d to evaluate robustness to future change 2. Complement (and integrate) existing \u201cHydrological Lines of Evidence\u201d 3. Lead to new generation of conceptual models that are (i) Robust to change (ii) Embody best science (iii) Workhorse for practical decisio", "label": "poster"}
{"text": "Presenter: Dr Dawn C. Rose Parkinson\u2019s is an incurable brain condition that affects people\u2019s movement and mood. As the disease progresses, more care is required impacting on the caregivers quality of life. Research Question: Does participating in activities together improve quality of life for caregivers of people with Parkinson\u2019s? Mixed methods: focus group (n=4), interviews (n=8) and survey (n=75, 16 male). Results 63% Parkinson\u2019s caregivers jointly participated in a large variety of activities Impact seemed gendered: Male caregivers reported better levels of personal care, and less anxiety, depression and stress in general. Significantly higher levels of stress revealed for females not participating in activities with the person they care for. Type of activity did not seem to impact quality of life. Authors: Lia Prado (MSc.) Rebecca Hadley (PhD.) University of Hertfordshire, UK, Dawn C. Rose (PhD.) Lucerne University of Applied Sciences and Arts, Switzerland Acknowledgments: The Parkinson\u2019s Advisory Team (University of Hertfordshire), and caregivers of people with Parkinson\u2019s who took part in this study. Taking Time: Carer Participation and Quality of Life APA Ref: Prado, L., Hadley, R., & Rose, D. (2020). Taking time: a mixed methods study of Parkinson\u2019s disease caregiver participation in activities in relation to their wellbeing. Parkinson\u2019s Disease, 2020. https://doi.org/10.1155/2020/7370810 Reasons Against\u2026 Working Taking time for self Seeing other friends Prefers other activities Promoting independence (both) Reasons For\u2026 Exercise Socialising Together Time Not enough time Empathetic Safe Space Qualitative Evidence \u201cI just need to think about myself a bit and not always be worrying, so now when she goes out I feel that I can just relax\u2026 So to just have a morning that I don\u2019t have to think about that it is actually quite nice. It sounds very selfish.\u201d \u201cI think the interesting thing is that you lose a lot of friends, because actually they don\u2019t understand it at all.\u201d \u201cWe both go to Parkinson\u2019s UK. I also committed to the support group because we got Parkinson\u2019s. It is something that we both need to cope with and we need people who understand what we are going through\u201d 0 20 40 60 80 Physical Social Home-based entertainment Daily acitvities Types of Activities and % Participation Male Carers Female Carers 0 20 40 60 Personal and Social Activities Anxiety and Depression Self-care Stress Factors of Wellbeing and % Quality of Life Compromised Male Carers Female Carers", "label": "poster"}
{"text": "Latest Results of Reactor Antineutrino Flux and Spectrum at Daya Bay - Antineutrino detected by inverse beta reaction (IBD) in Gd-loaded liquid scintillator \u2022 Prompt e+ signal : 1-10 MeV, determined by antineutrino energy \u2022 Delayed neutron capture signal: 8 MeV @ Gd \u2022 Time correlation: capture time is about 28 \u03bcs in 0.1% Gd-LS XXVIII International Conference on Neutrino Physics and Astrophysics, Heidelberg, 4-9 June 2018 Liang Zhan, Institute of High Energy Physics, Beijing on behalf of the Daya Bay Collaboration Reactor Antineutrinos at Daya Bay \u2022 Six reactors with a total thermal power of 17.4 GW \u2022 Antineutrino flux produced by fissions of isotopes: 235U, 238U, 239Pu , and 241Pu \u2022 Reactor operator provides generated thermal power (Wth) and fission fraction (fi /F) \u2022 ei : Energy release per fission for isotope i \u2022 Si(E\uf06e): Antineutrino energy spectrum for each isotope \u2022 \u03b1i : fission fraction Abstract The latest measurement of the reactor antineutrino flux and energy spectrum by the Daya Bay reactor neutrino experiment is reported. The antineutrinos were generated by six 2.9 GWth nuclear reactors and detected by eight antineutrino detectors deployed in two near (500 m and 600 m flux-weighted baselines) and one far (1600 m flux-weighted baseline) underground experimental halls. An improvement on the neutron detection efficiency determination was performed using a new neutron calibration campaign and dedicated data-simulation comparison. With a 1230-day data set, the IBD yield was measured to be (5.91\u00b10.09)x10-43cm2/fission. The ratio between the measured to predicted reactor antineutrino yield is 0.952\u00b10.014(exp.)\u00b10.023(model). The comparison of the measured IBD positron energy spectrum with the predictions is also reported with a previous 621-day data set. A reactor antineutrino spectrum weighted by the IBD cross section is extracted for model-independent predictions. Reactor Antineutrino Detection S: antineutrino flux from reactors \u03c3: cross section of inverse beta decay. L: baseline, surveyed with a precision of 28 mm. Psur : antineutrino survival probability, including the fit parameter sin22\u03b813 Np: number of target protons, determined by target mass. \u0404: detection efficiency - Antineutrino spectrum of IBD reactions An improvement on the determination of the neutron detection efficiency was performed compared with previous publication Reactor Antineutrino Flux Measurement - Determination of the neutron detection efficiency was improved using a new neutron calibration campaign and dedicated data-simulation comparison. - An extensive neutron calibration campaign was carried out in Daya Bay at the end of 2016. Two types of neutron sources ( 241Am-13C and 241Am-9Be) were deployed vertically in three calibration axis and the data in 59 different combinations of sources and locations was collected. - A benchmark quantity was defined on the neutron capture energy spectrum. - Good agreement between calibration data and simulation on the energy spectrum and F. - The neutron detection efficiency was determined to be (81.48%\u00b10.60%) with a reduction in the uncertainty by 56%. - A new measurement on the reactor antineutrino yield was performed using the 1230-day data which has average fission fractions of (0.571, 0.076, 0.299, and 0.054) for (235U, 238U, 239Pu , and 241Pu) Reactor Antineutrino Spectrum Measurement - Measured IBD prompt energy spectrum vs. prediction after normalization - Obvious discrepancy between data and prediction, significance was evaluated. - 3 \u03c3 for the whole spectrum - 4.4 \u03c3 for a 2-MeV energy window around 5 MeV - Uncertainty of the prompt energy spectrum - An antineutrino spectrum of IBD reactions is provided as an input for reactor neutrino experiments after unfolding the IBD prompt energy spectrum to antineutrino energy. - Consistent results by two unfolding methods: singular value decomposition (SVD) and Bayesian iteration Reactors: D1, D2, L1, L2, L3, and L4 Detectors: AD1, AD2, \u2026, AD8 - A variety of simulati", "label": "poster"}
{"text": "I-RIM Conference 2019 October 18 - 20, Rome, Italy ISBN: 9788894580501 Adaptive admittance control for a safe and ef\ufb01cient human-robot interaction Federica Ferraguti, Chiara Talignani Landi, Lorenzo Sabattini, Marcello Bonf`e, Cesare Fantuzzi and Cristian Secchi Abstract\u2014 The possibility of adapting online the way a robot interacts with the environment is becoming more and more important. Nevertheless, stability problems arise when the environment (e.g. the human) the robot is interacting with gets too stiff. In this work, we present a strategy for handling the stability issues related to a change of stiffness of the human arm during the interaction with an admittance-controlled robot. I. INTRODUCTION One of the most revolutionary and challenging features of the new generation of robots is physical human-robot interaction (pHRI). In pHRI tasks, robots are designed to coexist and cooperate with humans in applications such as assisted industrial manipulation, collaborative assembly, domestic work, entertainment, rehabilitation or medical ap- plications. In these contexts, due to the desired coexistence of robotic systems and humans in the same workspace, main concerns are related to safety and dependability. A widely used approach consists in implementing interaction control strategies that guarantee a compliant behavior of the robot. In particular, admittance control is typically utilized for controlling industrial robots, that are generally characterized by a stiff and non-backdrivable mechanical structure [1]. For example, admittance control has been used to imple- ment robot manual guidance in [2] and [3], by means of the \u201cwalk-through programming\u201d where the human operator becomes the teacher that physically guides the robot through- out the desired trajectory. When using admittance-controlled robots, instability can arise when interacting with stiff envi- ronments. Since humans are dynamic systems characterized by a time-varying impedance, they can behave in a stiff way and, consequently, give rise to instability when interacting with admittance-controlled robot. Instability induces, among other undesired effects, a deviation of the robot from the desired admittance behavior. Furthermore, it produces high amplitude oscillations of the end-effector, undermining the user safety during the interaction. The deviations have to be \ufb01rst promptly detected and then canceled (or reduced) to restore the stability of the system. The adaptation of the parameters of the admittance control is a common strategy for recovering the stability of the interaction as shown, e.g., in [4], [5] and [6]. In this work we show a novel strategy F. Ferraguti, C. Talignani Landi, L. Sabattini, C. Fantuzzi and C. Secchi are with the Department of Sciences and Methods for Engineering (DISMI), University of Modena and Reggio Emilia, Italy {name.surname}@unimore.it M. Bonf`e is with the Engineering Department, University of Ferrara, Italy marcello.bonfe@unife.it for detecting the rise of oscillations during the interaction between a human and an admittance-controlled robot and a parametric adaptation of the admittance for restoring a stable behavior. The proposed adaptation allows to keep the adaptive dynamics similar to the nominal one in order to avoid unbalancing effects and to increase the usability of the system. Preliminary results have been presented in [7] and [8], while in [9] a method for automatically setting the detection threshold using a thorough statistical analysis has been introduced. Moreover, a weighted energy allocation strategy has been proposed in order to consider separately translations and rotations. In this work we present the overall framework and we show the experimental validation of the control architecture. II. ADAPTIVE ADMITTANCE CONTROL The goal of the admittance control is to force the robot to behave in a desired way when interacting with the en- vironment. In this paper, we address the case of a robotic manipulator manuall", "label": "poster"}
{"text": "GALAXY CLUSTERS IN THE CFHTLS SARRON F. MARTINET N. ADAMI C. DURRET F. INSTITUT D\u2019ASTROPHYSIQUE DE PARIS (IAP) ARGELANDER-INSTITUT F\u00dcR ASTRONOMIE, BONN LABORATOIRE D\u2019ASTROPHYSIQUE DE MARSEILLE (LAM) INSTITUT D\u2019ASTROPHYSIQUE DE PARIS (IAP) Florian Sarron PhD student IAP (Paris) GALAXY EVOLUTION ACROSS TIME 12-16 JUNE 2017 There is a degeneracy between mass and redshift : only most massive clusters are detected at high redshift. Figure 6 shows the ETGs and LTGs fraction as a function of redshift for different cluster masses. The evolution in redshift for the full mass range is dominated by low mass clusters - the size of our sample enables us to study dependence on both parameters simultaneously. Fraction of ETGs and LTGs 0 0.2 0.4 0.6 0.8 1 0.2 0.4 0.6 Galaxy type proportion mean cluster redshift all M200 0.2 0.4 0.6 mean cluster redshift 1013.5 < M200 < 1014 Msun 0.2 0.4 0.6 mean cluster redshift 1014 < M200 < 1014.5 Msun 0.2 0.4 0.6 mean cluster redshift M200 > 1014.5 Msun NEXT : BREAKING THE REDSHIFT-MASS DEGENERACY Figure 6 There is some disagreement in the literature concerning the evolution with redshift of the galaxy luminosity function (GLF) in galaxy clusters. It is unclear whether the red sequence (RS) is enriched by ef\ufb01cient quenching of blue late-type galaxies inside the cluster from z~1, or if this RS is built at higher redshift. To explore this issue, we apply our new version of the Adami and MAzure Cluster FInder (AMACFI) to the Canada France Hawaii Telescope Legacy Survey (CFHTLS) W1 \ufb01eld. Figure 3 Schechter \u0001t parameters evolution for ETGs -1 -0.5 0.3 0.6 \u03b1 zclus -23 -22.5 0.3 0.6 M* zclus passive evolution - BC03 -1 -0.5 13.5 14 14.5 15 \u03b1 log(M200/Msun) -23 -22.5 13.5 14 14.5 15 M* log(M200/Msun) RESULT : ETGs GLFs faint end shows a mild decrease with redshift at 4.8 - meaning galaxies in clusters are ef\ufb01ciently quenched from z ~ 0.7. From the mass dependance we can infer that quenching is more ef\ufb01cient in denser environments. \u03c3 1 10 100 1000 10000 \u221228 \u221226 \u221224 \u221222 \u221220 \u221218 \u221216 \u03b1early=\u22120.79 \u00b1 0.02 M*early=\u221222.64 \u00b1 0.07 Galaxies / deg2 Mabs(i) 142 clusters at = 0.22 1 10 100 1000 10000 \u221228 \u221226 \u221224 \u221222 \u221220 \u221218 \u221216 \u03b1early=\u22120.80 \u00b1 0.03 M*early=\u221222.82 \u00b1 0.06 Galaxies / deg2 Mabs(i) 264 clusters at = 0.30 1 10 100 1000 10000 \u221228 \u221226 \u221224 \u221222 \u221220 \u221218 \u221216 \u03b1early=\u22120.74 \u00b1 0.03 M*early=\u221222.78 \u00b1 0.05 Galaxies / deg2 Mabs(i) 327 clusters at = 0.40 1 10 100 1000 10000 \u221228 \u221226 \u221224 \u221222 \u221220 \u221218 \u221216 \u03b1early=\u22120.61 \u00b1 0.03 M*early=\u221222.63 \u00b1 0.05 Galaxies / deg2 Mabs(i) 366 clusters at = 0.49 1 10 100 1000 10000 \u221228 \u221226 \u221224 \u221222 \u221220 \u221218 \u221216 \u03b1early=\u22120.55 \u00b1 0.04 M*early=\u221222.60 \u00b1 0.05 Galaxies / deg2 Mabs(i) 370 clusters at = 0.60 1 10 100 1000 10000 \u221228 \u221226 \u221224 \u221222 \u221220 \u221218 \u221216 \u03b1early=\u22120.58 \u00b1 0.05 M*early=\u221222.69 \u00b1 0.06 Galaxies / deg2 Mabs(i) 344 clusters at = 0.68 Figure 5 - Same as Figure 4 for stacks in bins of redshift of cluster GLFs. 1 10 100 1000 10000 \u221228 \u221226 \u221224 \u221222 \u221220 \u221218 \u221216 \u03b1early=\u22120.62 \u00b1 0.06 M*early=\u221222.76 \u00b1 0.07 Galaxies / deg2 Mabs(i) 453 clusters at = 6.74E+13 1 10 100 1000 10000 \u221228 \u221226 \u221224 \u221222 \u221220 \u221218 \u221216 \u03b1early=\u22120.90 \u00b1 0.07 M*early=\u221222.79 \u00b1 0.10 Galaxies / deg2 Mabs(i) 91 clusters at = 4.50E+14 1 10 100 1000 10000 \u221228 \u221226 \u221224 \u221222 \u221220 \u221218 \u221216 \u03b1early=\u22120.87 \u00b1 0.03 M*early=\u221222.89 \u00b1 0.05 Galaxies / deg2 Mabs(i) 622 clusters at = 1.71E+14 Figure 4 - Stacks in bins of mass of cluster GLFs. Best fit of Schechter parameters of ETGs is indicated. Vertical line is the 90% completeness limit of the sample - corresponding to i=23 in apparent magnitude. Composite GLFs of cluster candidates 0 0.2 0.4 0.6 0.8 1 0.3 0.6 0.9 Completeness zhalo Completeness for M200 > 1014 Msun 0 0.2 0.4 0.6 0.8 1 1 2 3 4 5 6 Completeness M200,halo [1014 Msun] Completeness for M200 > 1014 Msun 0.6 0.8 1.0 0.3 0.6 0.9 Purity zphot Purity for M200 > 1013 Msun S/N > 3 S/N > 4 S/N > 5 13.0 13.5 14.0 14.5 15.0 0.3 0.6 0.9 log(M200/Msun) zphot SN > 4 13.0 13.5 14.0 14.5 15.0 0.3 0.6 0.9 0 0.2 0.4 0.6 0.8 1 We apply AMACFI to ", "label": "poster"}
{"text": "Databases and web-based software tools for HR-pyPopStar models and MEGASTAR library Moll\u00e1 Lorente, M. 1 ; Garc\u00eda-Vargas, M. 2; Carrasco Licea, E. 3; Mujica \u00c1lvarez, E. 2 & Mill\u00e1n-Irigoyen, I. 1 1CIEMAT (Madrid, Spain), 2FRACTAL S.L.N.E. (Madrid, Spain), 3INAOE (Puebla, Mexico) MEGASTAR is a stellar spectral atlas for MEGARA (Multi Espectr\u00f3grafo en GTC de Alta Resoluci\u00f3n para Astronom\u00eda). MEGARA is an optical (3650 \u2013 9750 \u212b), fiber- fed, medium-high spectral resolution (R = 6000, 12000, 20000) instrument in operation on the GTC 10.4m telescope. The scientific exploitation of MEGARA demanded a stellar-spectra library to interpret galaxy data and to estimate the contribution of the stellar populations. MEGASTAR atlas is focused on the highest resolution setups, HR-R and HR-I, and already has almost 1000 stars (twice spectra) thanks to the filler-type OpenTime obtained up to now in 7 semesters. We have developed a web- based tool and a database that allow working in the project (for MEGASTAR team) and making the observations and products available to the scientific community. MEGASTAR WebApp Functionalities: \u00a7 Visualization and search of the sources involved in the project (link to the SIMBAD database). \u00a7 Visualization, search, download and plot the data product files (by using a java tool) of the observations. \u00a7 Paint a graph of the stars grouped by three ranges of [Fe/H] as follows: all stars of the library, the observed stars of the library or the user stars uploaded by a file. \u00a7 Download the releases of the reduced star spectra. \u00a7 Download the statistics files: observations statistics by VPH and by stellar physical parameters. MEGASTAR WebApp Technologies: \u00a7 Web Servers: Apache and Tomcat \u00a7 Database: MySQL \u00a7 Languages: Java, Java Servlets, HTML and JavaScript \u00a7 Libraries: JFreeChart, Plotly and nom.tam FITS HR-pyPopStar WebApp Functionalities: \u00a7 Detailed description of the HR-pyPopStar models. \u00a7 Models Download. \u00a7 Plot spectra from the HR-pyPopStar Library. \u00a7 Plot synthetic properties resulting from SSP SEDs. \u00a7 Combine spectra from the HR-pyPopStar Library. HR-pyPopStar WebApp Technologies: \u00a7 Web Servers: Apache and Tomcat. \u00a7 Database: MySQL. \u00a7 Framework: Google Web Toolkit (GWT). \u00a7 Languages: Java, Java Servlets, HTML and JavaScript. \u00a7 Libraries: JFreeChart and nom.tam FITS. HR-pyPopStar model provides a complete set of high resolution (HR) Spectral Energy Distributions (SEDs) of Single Stellar Populations. The model uses the most recent high wavelength-resolution theoretical atmosphere libraries for main sequence, post-AGB/planetary nebulae and Wolf-Rayet stars. The SEDs are given for more than a hundred ages ranging from 0.1 Myr to 13.8 Gyr, four different values of the metallicity (Z = 0.004, 0.008, 0.02 and 0.05), and four different IMFs. We have developed a public web-based software tools and a database to manage HR-pyPopStar models and to make this available to the users community. References: Garc\u00eda-Vargas et al. , 2020, MNRAS, 493, 871. DOI: 10.1093/mnras/staa126; Carrasco et al., 2021, MNRAS, 501, 3568. DOI: 10.1093/mnras/staa3704; Moll\u00e1 et al. 2022, submitted. References: Mill\u00e1n-Irigoyen et al. (2021), MNRAS, 506, 4781. https://doi.org/10.1093/mnras/stab1969", "label": "poster"}
{"text": "SCHOOL OF ROCK 2016 UN\u2019INSEGNANTE ITALIANA SULLA JOIDES RESOLUTION Cicconi A. 1,2 1. Liceo Scientifico \u201cG. Marinelli\u201d, Udine; 2. School of Science and Technology, University of Camerino, Camerino COSA TROVERETE IN QUESTO POSTER Lo scopo di questo poster \u00e8 raccontare l\u2019esperienza della prima insegnante italiana a bordo della Joides Resolution per partecipare ad un corso di formazione per docenti di Scienze: School of Rock. Attivit\u00e0 sulla Joides Resolution LEZIONI IN AULA Ogni giorno sono state svolte diverse ore di lezione teorica al fine di costruire le basi per la comprensione di complicati articoli scientifici sulla paleoclimatologia delle carote di sedimento oceanico. A TU PER TU CON LE CAROTE Ricercatori esperti nel settore ci hanno mostrato come vengono analizzate le carote di sedimento raccolte dalla Joides Resolution. VETRINI\u2026VETRINI\u2026E ANCORA VETRINI \u2026 JOIDES RESOLUTION La Joides Resolution \u00e8 una nave oceanografica per carotaggi sul fondale marino. La nave \u00e8 propriet\u00e0 della societ\u00e0 Siem Offshore AS ma lavora per IODP (International Ocean Discovery Program). Gli scienziati che lavorano sulla JR vengono da tutto il mondo. In ogni spedizione, sulla nave, \u00e8 presente un docente di scienze che si occupa della divulgazione. \u2026 IODP L\u2019International Ocean Discovery Program \u00e8 un programma di ricerca che vede la collaborazione di 25 Nazioni. Lo scopo \u00e8 quello di studiare la storia e la dinamica della Terra a partire dallo studio dei fondali oceanici. Il piano scientifico 2013-2023 ha un titolo pi\u00f9 che significativo: \u00abIlluminating Earth\u2019s Past, Present and Future\u00bb Sponsor principali di questo programma sono: la National Science Foundation (USA), Il Ministero dell\u2019Educazione, Cultura, Sport, Scienza e Tecnologia (JAPAN) e l\u2019 ECORD (European Consortium for Ocean Research Drilling). \u2026 SCHOOL OF ROCK School of Rock \u00e8 un corso di formazione per docenti organizzato da IODP con lo scopo di divulgare, creando dei docenti esperti, le attivit\u00e0 di ricerca che si svolgono sulla JR. Nel 2016 sono stati selezionati 16 docenti di cui 14 Statunitensi, una docente Francese e per la prima volta una docente Italiana. \u2026 DOCENTI E RICERCATORI INSIEME! La caratteristica di School of Rock che ne fa un corso di aggiornamento per docenti di elevato valore formativo sia dal punto di vista didattico ma anche scientifico \u00e8 la presenza, come formatori, di ricercatori attivamente coinvolti nelle spedizioni di Joides Resolution. Gli insegnanti li hanno affiancati nell\u2019analisi delle carote di sedimento e nella lettura dei dati proprio come dei veri ricercatori. CONNESSI CON IL RESTO DEL MONDO Ogni giorno i docenti hanno gestito un Blog sulle attivit\u00e0 svolte sulla nave o all\u2019esterno nonch\u00e9 aggiornato la pagina Facebook e Twitter. Inoltre sono stati organizzati collegamenti con scuole dei propri Paesi. FACCIAMO LA CONOSCENZA CON\u2026 Nella foto a sinistra il ricercatore Larry Krissek della Ohio State University ed io che lo intervisto e trasmetto con un tablet ad una classe collegata dall\u2019Italia (foto a destra). SCHOOL OF ROCK 2016 DOVE All\u2019interno della Joides Resolution ancorata al porto di Cape Town (Sud Africa). QUANDO Dal 29 Maggio al 6 Giugno 2016. CHI 16 docenti di scienze di cui 14 Statunitensi, una docente Francese ed una docente Italiana. COSA Exploring Ocean Cores and Climate Connections: From Antarctica Across the Southern Ocean. \uf0d8L\u2019Antartide \u00e8 stato sempre coperto dai ghiacci? \uf0d8L\u2019estensione del ghiaccio marino \u00e8 stata sempre la stessa? \uf0d8Quali informazioni si ricavano dalle carote di sedimento oceaniche estratte nell\u2019Oceano Meridionale? \uf0d8Come si interpretano i dati relativi ai fossili presenti nelle carote? \uf0d8Come \u00e8 cambiato il clima nel passato della Terra? Questi sono stati alcuni degli interrogativi a cui si \u00e8 cercato di dare una risposta esclusivamente utilizzando i dati ricavati dalle carote (Data Driven Education) utilizzando quindi lo stesso procedimento di indagine usato dagli scienziati. Le escursioni sono state guidate da docenti dell\u2019Universit\u00e0 di ", "label": "poster"}
{"text": "2D Two-Temperature Model Numerical Study Of Formation Mechanisms Of Periodic Surface Structures Induced On Silicon Under Femtosecond Laser Irradiation T. JY. Derrien1, R. Torres1, T. Sarnet1, M. Sentis1, T. E. Itina2 1 Lasers, Plasmas and Photonic Processes Laboratory (LP3 UMR 6182 CNRS), 163 av. de Luminy, Case 917, 13288 Marseille, France 2 Hubert Curien laboratory, UMR CNRS 5516/Universit\u00e9 Jean Monnet, 18 rue du Professeur Benoit Lauras, 42000, Saint Etienne, France Contacts PhD std: thibault.derrien@lp3.univ-mrs.fr CNRS researcher: tatiana.itina@univ-st-etienne.fr Surface wave investigations Context Lifetime of a fs interference in Si Does melting occur under fs pulse on Si ? CINES computational center and French Ministry of Research PhD support are gratefully acknowledged. Additional thanks to D. Grojo, I. Bogatyrev, and A. Nikitin. \u00ab Spikes \u00bb Black silicon. \u00ab Agregation \u00bb Amplification Increasing number of 100 fs, 1 kHz shots \u00ab Ripples \u00bb LIPSS \u00ab Beads \u00bb Saturation Problem: Formation mechanisms are not well-known. -- Objective: Identify the mechanisms of : 1. Periodic modification of the electron-hole plasma created by femtosecond laser irradiation 2. Transmission of the pattern from electrons to lattice 3. Change of order and amplification of the nanostructures Interplay between Electron-lattice coupling and Diffusion of Electrons Conclusion Fusion Resolidification Recrystallisation References. - ~45 nm melted and resolidifcated depth (0.42 J/cm2, 130 fs) [J. Bonse, Applied Surface Science 221, 215 (2004)] - Melting occurs from 0.2-0.5 J/cm2 [NM Bulgakova, Physical Review B 69, 054102 (2004)], [DP Korfiatis, Journal of Physics D 40, 6803 (2007)] Bulk silicon Melting starts at ~0.4 J/cm\u00b2. ~115 nm melted at 0.5 J/cm\u00b2. Laser fluence (J/cm\u00b2) Electron temperature Free \u2013 carrier density Lattice temp. Melting Critical density Model includes: \u2022Electron and Lattice temperatures (heating, coupling, diffusion, cooling). \u2022Free-electron and hole density (1-2 photon ionization, electronic avalanche, convection, recombination) \u2022Fresnel formulas of reflectivity and inverse Bremmstrahlung absorption \u2022Drude model (EM behaviour) \u2022Electron-phonon and electron-electron collisions are considered. EM plasmonic interference is modeled and the possibility of printing the pattern from electrons to lattice is checked. Result is : for high fluence, convection-diffusion is dominant on electron-lattice coupling, for low-fluence, it is possible to observe a priodic modification in lattice temperature profile. On these figures, F=500 mJ/cm\u00b2. Calculated free-electron density, electron and lattice temperature are presented for a 500 mJ/cm\u00b2 laser fluence, 800 nm NIR wavelength, and 100 fs pulse duration (FWHM). It has been reported that c-Si (100) melts from 0.2 J/cm\u00b2 under ~100 fs laser irradiation. Our calculations based on a melting temperature criterium showed that, if melting occurs, resolidifcation front velocities are higher than maximum speed of recrystallisation, thus should be observed. However, calculations based on fusion enthalpy showed that no melting occurs. Our experimental measurements show that no melting/recrystallisation front is observable on Transverse Electron Microscopy pictures of the Si-protection layer interface. - Calculations showed that thermal processes (melting, evaporation, \u2026) are not the mechanisms responsible for pattern transmission from electron to the lattice. Ablation may occur, but an ultrafast mechanism of ablation (~200 fs at 500 mJ/cm\u00b2) is required to support the interference hypothesis. - Calculations confirm the possibility of the surface electromagnetic wave (plasmon) to be responsible for ripple formation under fs laser irradiation, through the modification of absorption provided by a seed (defects, roughness, nanoparticle) under our conditions. - Calculations and experiments show that no melting occurs during ripple formation. - Experiments show that mechanism of ripple-to-beads transition occurs in a crysta", "label": "poster"}
{"text": "Snip \u2013 User Centric Collaborative ELN Markus Osterhoff, Sebastian B. Mohr, Sarah K\u00f6ster Georg-August-Universit\u00e4t G\u00f6ttingen R\u00f6ntgenphysik | CIDAS | SFB 1456 internet server analysis catalogue sample DB CONTROL meta data raw data experiment discussion users discussing with colleagues mobile access \u2026! \u2026? \u2026!? \u2026? con\ufb01g positions, parameters images, links data decisions feedback User Centric Paradigm \u2013 Documenting Non-Linear Discussions and Experiments Examples Creative, Collaborative Collage \u25ba \u25bacomputer-generated contents (API) \u25ba \u25bahandcrafted annotations (pen entry) \u25ba \u25bareal-time communication (web based) Curated Lab Book \u25ba \u25baputting the experimental state into context \u25ba \u25bavia API: parameters, images, URLs \u25ba \u25bavia pen & text: highlights, thoughts, sketches \u25ba \u25babringing machine-readable snips into perspective Closing the Loop \u25ba \u25baExperiment \u21d2 Thoughts \u21d2 Decisions \u21d2 Experiment Acknowledgements We thank Jan Goeman for outstanding technical support. Funding by Deutsche Forschungsgemeinschaft (SFB 1456), DAPHNE4NFDI and the G\u00f6ttingen Campus Institute Data Science is gratefully acknowledged. API / Data Ingestion \u25ba \u25bainteroperable with other software: instruments send their state, users discuss and comment \u25ba \u25bapublic JSON-endpoint accepts standardised snips: API tokens per book for authentication \u25ba \u25bacustom snip types: hierarchical namepaces prevent conflicts between groups Single / dual page layout Upload / place new snips Doodle tool Hyperlinks Permission system Creative collage JSON snip sci.photos/ QR/FDM24 snip. roentgen. physik.uni- goettingen. de Current Status & Outlook Client/server architecture \u25ba \u25baReact in TypeScript, serviced by node.js \u25ba \u25baextensible and modular, custom snips and render functions In production @ GINIX X-ray microscope (DESY, Hamburg) \u25ba \u25bamacros send content to lab book \u25ba \u25baintegration into other beamlines under development In production @ IRP \u25ba \u25balab experiments, personal ELNs; shared experiments \u25ba \u25ba150 books, > 20k pages; ~ 30k snips, ~ 500k doodles Feature Status live update, working collaboratively yes free-form input; pen entry, sketches; images yes machine-readable data, data ingestion via API yes; namespaces and schemas permissions (r/w; API token; r/o token) yes; user-defined groups searching and filtering yes tagging system (table of contents, flags) under discussion hyperlinks to external systems yes federated login, SSO work in progress removing contents during grace period automatic creation of lab book could be implemented Snip types \u25ba \u25baBasic types: image, text, doodle URLs linking to SciCat, Sample DB, PID services etc. \u25ba \u25baArray: composite snips \u25ba \u25baUser defined types: timestamp, motor positions, macro, log, measurement, Jupyter analysis, \u2026 Book browser MariaDB page -, book -, user data, ... Render service Preview storage trigger server side rendering preview images signup pw reset Email service real time updates Websocket trigger updates static client \ufb01les API requests fetch data", "label": "poster"}
{"text": "The characterization of the water vapor vertical distribution on Mars is currently a very active research topic. Until this last decade, the water cycle has been studied mainly with the analysis of column density abundances. The recent possibility of solar occultation (SO) observations has opened a new path towards a better understanding of the Martian climate [1]. The Mars we observe today is a dry and cold planet although there are abundant evidences suggesting a warmer and wetter environment in the past [2]. Despite being a minor species in the current Martian atmosphere (~0.03%), water vapor has a large variability throughout the year, resulting in a very complex hydrological cycle involving sublimation and condensation processes affected by dust and atmospheric transport [1]. Global Dust Storm Data analysis Super\u00adsaturation and water ice Seasonal variation Contact: adrianbm@iaa.es WATER VAPOR VERTICAL DISTRIBUTION ON MARS DURING 5 YEARS OF EXOMARS\u00adTGO/NOMAD OBSERVATIONS A. Brines1, M. A. L\u00f3pez\u00adValverde1, A. Stolzenbach1, A. Modak1, B. Funke1, F. G. Galindo1, S. Aoki2,3, G. L. Villanueva4, G. Liuzzi4,5, I. R. Thomas2, J. T. Erwin2, U. Grabowski6, F. Forget7, J.J. Lopez\u00adMoreno1, J. Rodriguez\u00adGomez1, F. Daerden2, L. Trompet2, B. Ristic2, M. R. Patel8, G. Bellucci9 and A. C. Vandaele2 1Instituto de Astrof\u00edsica de Andaluc\u00eda (IAA/CSIC), Spain\u037e 2Royal Belgian Institute for Space Aeronomy, Belgium\u037e 3Department of Complexity Science and Engineering, University of Tokyo, Japan\u037e 4NASA Goddard Space Flight Center, USA 5American University, Washington DC, USA\u037e 6Karlsruhe Institute of Technology, Karlsruhe, Germany\u037e 7Laboratoire de M\u00e9t\u00e9orologie Dynamique, IPSL, Paris, France\u037e 8Open University, UK\u037e 9Istituto di Astrofisica e Planetologia, Italy VII Reuni\u00f3n de Ciencias Planetarias y Exploraci\u00f3n del Sistema Solar Valladolid 11, 12 y 13 de julio de 2023 Here we present a summary of results about the characterization of the water vapor in the Martian atmosphere. We study its seasonal variability during 3 Martian Years (MY) analyzing almost 5 years (April 2018 to December 2022) of NOMAD SO observations. We present a detailed insight of specific periods showing the effects of dust storms and detections of supersaturation. NOMAD is an infrared spectrometer covering the spectral range between 0.2 to 4.3 \u00b5m. Its SO uses an echelle grating with with an Acousto\u00adOptical Tunable Filter (AOTF) to select different diffraction orders to be used during the observations. The spectral resolution of the SO channel is \u03bb/\u2206\u03bb = 20,000. The sampling allows a vertical resolution of 1 km. Also, the AOTF permits probing the atmosphere at a given altitude through 6 different diffraction orders [7]. For this study, we use Level 1 SO calibrated transmittances [8] of diffraction orders 134 (3011\u00ad3035 cm\u00ad1), 136 (3056\u00ad3081 cm\u00ad1) for the lower atmosphere and 168 (3775\u00ad3806 cm\u00ad1), 169 (3798\u00ad3828 cm\u00ad1) for the upper atmosphere. We have developed pre\u00adprocessing tools to identify and eliminate residual artifacts in the spectra (bending, spectral shift) using the line\u00adby\u00adline radiative transfer algorithm KOPRA [9]. For the inversions, we use the latest calibration of the NOMAD AOTF and its instrumental line \u00ad shape (ILS) [10]. The retrievals are done combining the spectra of low altitude orders (134,136) with spectra of high altitude orders (168,169) up to 120 km for occultations where those orders where observed simultaneously. The bottom panels show two examples of typical NOMAD spectra (black) after its bending and spectral shift corrections for diffraction orders 136 (panel A) and 169 (panel B) at 30 and 100 km respectively. We also show the fitting after the retrieval (red). For optimization purposes, we only fit the data at certain spectral windows where the strongest H2O absorption lines are located. The panel on the right shows a typical retrieved H2O vertical profile (blue) and the GCM a priori used during its inversion. For this example, we are not fitting the data", "label": "poster"}
{"text": "References Ran E, et al. (2013) Alternative cleavage and polyadenylation: extent, regulation and function. Nature Reviews Genetics 14, 496-506. Simpson JT, et al. (2009) ABySS: a parallel assembler for short read sequence data. Genome Research 19, 1117-1123. Robertson G. et al. (2010) De novo assembly and analysis of RNA-seq data. Nature Methods 7, 909-912. Trapnell C, et al. (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nature Biotechnology 28, 511-515. Grabherr MG, et al. (2011) Full-length transcriptome assembly from RNA-Seq data without a reference genome. Nature Biotechnology 29, 644-652. Djebali S, et al. (2012) Landscape of transcription in human cells. Nature 489, 101-108. Abreviations 3\u2019-end \u2013 Downstream end 5\u2019-end \u2013 Upstream end ABySS \u2013 Assembly by short sequences APA \u2013 Alternative polyadenylation CDS \u2013 Coding DNA sequence CS \u2013 Cleavage site DNA \u2013 Deoxyribonucleic acid ENCODE \u2013 Encyclopedia of DNA elements EST \u2013 Expressed sequence tag FDR \u2013 False discovery rate PET \u2013 Paired-end tag Poly(A) \u2013 Polyadenylation PPV \u2013 Positive predictive value RNA \u2013 Ribonucleic acid RNA-Seq \u2013 Whole transcriptome shotgun sequencing ROC \u2013 Receiver operator characteristic SPAT \u2013 Searching for poly(A) tails TPR \u2013 True positive rate Trans-ABySS \u2013 Transcriptome ABySS UTR \u2013 Untranslated region WIG \u2013 Wiggle format 1. Overview Acknowledgements In cancers, alternative splicing and polyadenylation (APA) can affect transcript stability, transport and translation, and can change a transcript\u2019s translated sequence. APA can be characterized with short-read sequencing using specialized library construction methods. For large-scale disease studies, however, it is desirable to characterize splicing and APA from a single library construction and sequencing run. In the work reported here, we describe SPAT, an analysis tool that uses de novo assembly of RNA-Seq data to Search for Poly(A) Tails. SPAT is designed to accept contigs from a range of de novo transcriptome assemblers. When used with Trans- ABySS, the overall pipeline reports fusions and rearrangements, indels, alternative splicing, and a range of types of APA. SPAT: Searching for Poly(A) Tails in RNA-Seq de novo Assemblies Raymond AGJ, Robertson AG, Chiu R, Mungall K, Nip KM, Kreitzman M, Jackman SD, Karsan A and Birol I 2. RNA-Seq Assembly and Poly(A) Tail Detection RNA-PET Clusters Using data supplied by ENCODE for cell line A459, we first thresholded peaks in RNA-PET coverage tracks, then clustered peaks that occurred within 100bp of each other. We used the resulting clusters as \u2018true\u2019 events for validations and ROC-like curves. ROC-Like Curve true positive | An RNA-PET cluster with at least one CS call within 100bp. false positive | A CS call that is not within 100bp of an RNA-PET cluster. true negative | Cannot be defined. false negative | An RNA-PET cluster with no CS call within 100bp. 3. Comparing Cleavage Site Calls RNA-Seq Tools Trans-ABySS/SPAT | Assemble with Trans-ABySS and process with SPAT. Trinity/SPAT | Assemble with Trinity and process with SPAT. Cufflinks | Assemble with Cufflinks and call CSs at transcript ends. ROC-like curves, which were insensitive to thresholds for RNA-PET peak detection and clustering, show that SPAT works with other assemblers, and performs better than a method that uses annotations to determine ends of expressed 3\u2019 UTRs. SPAT has a PPV of 90% when we require an RNA-PET coverage of 3 and 2 bridging reads supporting a CS call. Validation Counts Venn diagrams were generated with the true positives from each tool set. Increasing RNA-PET stringency reduces the number of true positives by 6% for Trans-ABySS/SPAT and 27% for Cufflinks. We thank the ENCODE consortium for supplying the resources that made this analysis possible. We gratefully acknowledge funding from Genome BC, Genome Canada, and the BC Cancer Foundation. Trans-ABySS Assembly Assembly involves constructing", "label": "poster"}
{"text": "KNOW W HAT YOU EAT GET THE MOBILE APP Fish supply chain traceability at your \ufb01ngertips, for an informed and conscious choice. NOVAFOODIES GET THE APP SCAN QR CODE DISCOVER This project has received funding from the European Union under Grant Agreement N\u00b0 101084180. \u00a9 All registered trademarks and logos mentioned in this document are the property of their respective owners. Co-funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily re\ufb02ect those of the European Union. Neither the European Union nor the granting authority can be held responsible for them.", "label": "poster"}
{"text": "The ESCAPE project is working toward the implementation of FAIR principles for Astrophysics ESFRI by using IVOA standards in the context of connecting the Virtual Observatory framework to the European Open Science Cloud. The scientists, software engineers, and data experts from the different facilities are addressing the \u2018data stewardship\u2019 challenges for a wide range of different data products and services. The recent ESCAPE Technology Forum event identified a number of important topics in the different domains from Radio Astronomy to Solar Physics: Connecting to the European Open Science Cloud Data stewardship of next-generation data products and services related to ESFRI and other astrophysics infrastructures M. Allen1, S. Amodeo1, F. Bonnarel1, M. Molinaro2, F. Genova1, M. Romaniello3, H. Heinl1 , A. Schaaff1, S. Lesteven1 Application of IVOA standards for solar physics data: \u00a7 Metadata for the semantics of the content (Unified Content Descriptors \u2018UCD\u2019 standard) \u00a7 Table Access Protocol for finding and using tabular data Solar Physics Standards: \u00a7 Data Provenance implementations \u2013 \u201cAllowing users to access quality and reliability information.\u201d \u00a7 Application of IVOA Data Models \u00a7 Support for multi-messenger approach (VO events, schedules, alerts) High Energy Astrophysics First steps for neutrino data in VO : \u00a7 Publication of Tables \u00a7 Publication of Events \u00a7 Integration into multi-messenger astrophysics systems \u00a7 Data provenance standards \u00a7 Using VO tools (e.g. TOPCAT, Aladin) \u00a7 Complementarity with the services of the KM3NeT Open Data Center Neutrino Astrophysics Standards: \u00a7 Standards for discovery of interferometric data \u2013 \u201cMake the data easy to find!\u201d \u00a7 Data provenance \u2013 \u201cWhat happened to these data?\u201d \u00a7 Data models \u2013 \u201cWhat metadata is needed for discovery and interoperability?\u201d Accessing and using radio astronomy data: \u00a7 Zoomable interactive access to large simulations on the sky (HiPS standard) \u00a7 Access to VO services for radio data from python Radio and millimetre Astronomy \u00a7 Standards and tools for GW follow-ups: \u00a7 Sky coverage standards \u00a7 Indexing the sky in space and time (HIPS, MOC 2.0) \u00a7 See- A full presentation by G. Greco Gravitational Wave astronomy ACRONYMS ESCAPE: European Science Cluster of Astronomy & Particle Physics ESFRI Research Infrastructures ESFRI: European Strategy Forum on Research Infrastructures FAIR: Findable, Accessible, Interoperable, Reusable HiPS: Hierarchical Progressive Survey IVOA: International Virtual Observatory Alliance MOC: Multi-Order Coverage Deep learning for adding value to the ESO archive data \u2013 \u201dlet the data speak\u201d \u00a7 e.g. search for similar spectra \u00a7 See -- Sedaghat et al. 2021 Optical/UV/IR Astronomy VO standards in the ESO archive for: \u00a7 linking data (Datalink standard) \u00a7 image cutouts (SODA standard) \u00a7 Large-scale imaging (HiPS standard) See -- Romaniello et al. 2018 ESCAPE - The European Science Cluster of Astronomy & Particle Physics ESFRI Research Infrastructures has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under Grant Agreement no. 824064. 1 CNRS, Observatoire astronomique de Strasbourg, France 2 INAF, Osservatorio Astronomico di Trieste, Italy 3 ESO \u2013 European Southern Observatory", "label": "poster"}
{"text": "Accuracy assessment of MERRA-2 temperature and humidity profiles over the tropical ocean using AEROSE observations and ECMWF analysis Bingkun Luo1, Peter J Minnett1, Goshka Szczodrak1, Nicholas R. Nalli2 \u2022Reanalysis model output is extensively used in atmospheric research to complement the satellite and in situ data. NASA's Goddard Earth Sciences Modern-Era Retrospective analysis for Research and Applications v 2 (MERRA-2) assimilates measurements from different sources to minimize bias errors. The model data must be rigorously evaluated to assess their suitability to study a variety of questions. Here, Sea Surface Temperature (SST) and profiles of temperature and humidity through the marine atmosphere from MERRA-2 are compared to independent ship-based measurements of radiosondes, and retrievals from the ship-based Marine-Atmosphere Emitted Radiance Interferometer (M-AERI), and also the analyses fields of the European Center for Medium - Range Weather Forecasting (ECMWF). The ship measurements include those from Aerosol and Ocean Science Expedition (AEROSE) cruises of the NOAA Ship Ronald H. Brown in the tropical North Atlantic Ocean, focusing on the representation of the spatial and temporal variability. The results reveal that temperature and water vapor profiles from the MERRA-2 are in good agreement with the in situ measurements. For part of the cruises, the atmosphere included a mid-level dry layer emanating from North Africa, the Saharan Air Layer (SAL). With respect to difference, MERRA-2 humidity profiles shows a big difference (40%) with RAOBs at high altitude (pressure level < 300 hPa). These results support the use of MERRA-2 fields in a variety of research applications, including those directed at improving the accuracies of satellite-derived SSTskin retrievals. Abstract The MERRA-2 SST agrees well with M-AERI, and it has a mean bias of 0.125 K and have the potential to provide a satisfactory contribution to studies involving SST. The SST difference distribution between them shows there is negative bias near equatorial region, effort is still required to provide better data especially some water vapor-contaminated data. Table: Statistics of errors of MERRA-2 SST vs M-AERI 2. SST Validation \uf0d8MERRA-2 datasets: \uf0a7The NASA MERRA-2 reanalysis data were generated using the Goddard Earth Observing System data assimilation system by NASA's Global Modeling and Assimilation Office Data Assimilation System V5.12.4. \uf0a7Covering the earth observation data from 1980 to present. \uf0a7MERRA-2 analysis data are computed on a latitude\u2013 longitude-altitude cubed sphere grid at the same spatial resolution as the 3DVAR algorithm atmospheric model based on the Grid-point Statistical Interpolation. \uf0d8AEROSE: \u2022 A series of intensive field campaigns on the NOAA ship Ronald H. Brown in the Atlantic Ocean. \u2022 AEROSE data include complementary measurements to study the transport of aerosols from the African continent across the Atlantic Ocean, including: \u2013Microphysical evolution and regional impacts \u2013Regional atmospheric chemistry and marine meteorology AEROSE tracks, color indicates the days since departure. \uf0d8Independent Validation data: \u2022Radiosonde (RAOB): Balloon-based instrument to make direct in situ measurements of air temperature, humidity, and pressure to about 30 km height. \u2022 ECMWF: Contains a set of atmospheric variables on a spatial horizontal grid of 0.5ox 0.5 o at 60 vertical levels. The ECMWF analysis is produced daily for 00, 06, 12 and 18 UTC. The four analyses per day are obtained by four- dimensional variational analysis (4DVAR) schemes. \u2022 M-AERI: An accurate, self- calibrating, Fourier transform IR spectroradiometer that measures emission spectra from the sea and atmosphere. (Minnett et al. 2001). 1. Data 19th International GHRSST Science Team Meeting 4th-8th June 2018, EUMETSAT, Darmstadt, Germany Relative Humidity and temperature layer properties of RAOB, MERRA-2 and ECMWF during 2015 AEROSE cruise, color indicates RH and temperat", "label": "poster"}
{"text": "Holocene sea-level changes in Southeast Asia 1 2 3 4 5 1 M. Bender , T. Mann ,D. Kneer , P. Stocchi , J. Jompa , A. Rovere Sea Level & Coastal Changes SLCC Acknowedgments: This work is supported through the grant SEASchange from the Deutsche F\u00f6rderungsgemeinschaft (DFG) as part of the Special Priority Program (SPP) 1889 Regional Sea Level Change and Society\u201c (SeaLevel). The Sea Level and Coastal Changes group research is supported by the Institutional Strategy of the University of Bremen, funded by the German Excellence Initiative [ABPZuK-03/2014] and by ZMT, the Leibniz Centre for Tropical Marine Research 1: MARUM \u2013 Center for Marine Environmental Sciences, University of Bremen, Bremen, Germany 2: ZMT \u2013 Leibniz Centre for Tropical Marine Research, Bremen, Germany 3: Alfred-Wegener-Institut, Bremerhaven, Germany 4: NIOZ Royal Netherlands Institute for Sea Research, Den Burg, Texel, Netherlands 5: Universitas Hasanuddin - Department of Marine Science Indonesia - Makassar RSL results from fossil microatolls in the Spermonde Archipelago, Indonesia, SE Asia Affiliations References modern microatoll fossil microatoll In this study we surveyed fossil microatolls on \ufb01ve new islands and living microatolls and compared the relative sea level (RSL) estimates with previous data provided by Mann et al., 2016. Figure 1) the locations and close- ups of the surveyed islands. Panel a-b) provide overview of study areas, sorted by letters as indicated in b). The islands Panambungan (g) and Barrang Lompo (i) were surveyed by Mann et al., 2016. The red S. indicates a third island from Mann et al., 2016 where only living microatolls are found. This island is not shown here (see \ufb01gure 3 for LMA elevations). Figure 2) All related RSL curves derived from fossil microatolls and their modern counterparts. Panel a) the positions of the islands are indicated by letters and colors and correlate to RSL graphs. All islands show comparable RSL results except the data set from Barrang Lompo, which shows a noticeable low RSL curve. The two studies from De Klerk, 1982 and Tjia et al.1972 show RSL results up to 6 meter above the present sea level, whereas the new data and the data by Mann et al., 2016 show RSL results of less than one meter above today. One possible explanation is that the earlier RSL results re\ufb02ect extreme storm or tsunami events. Additionally, the GIA predictions mismatch the data and therefore,we propose to explore di\ufb00erent ice models e.g. ICE-6G by Peltier et al., 2015 or ANICE ( De Boer et al., 2014). Figure 4) RSL indicator points for the Spermonde Archipelago and the ICE-5G GIA model (Peltier, 2004) and \ufb01ve di\ufb00erent mantle viscosities for the same area. The gray band indicates the lowest and highest GIA prediction for this region. Shown are two marine limiting points from Tjia et al.,1972, 16 marine and two terrestrial limiting and one index point by De Klerk,1982, 21 sea-level index points from Mann et al.,2016 and the 24 newly surveyed data points. Comparison with data from literature -0.4 -1 -0.8 -0.6 -0.2 0 Elevation [m] Sanane -1 Sanrobengi Barrang Lompo Panambungan Tambakulu n=24 n=23 n=20 n=17 n=51 Our results for the living microatoll surveys show a clear geographic trend in the HLC. The highest HLC was measured on Sanrobengi. This island is placed only one km from the coast of Southwest Sulawesi. The HLC from Sanane, Panambungan and Barrang Lompo di\ufb00er slighty from each other but they are within a comparable range. These islands are located in the middle of the Archipelaho. On Tambakulu the HLC signal is the lowest. It is placed at the outer part of Spermonde ~70 km from the coast of the mainland. This trend might be based on di\ufb00erences in the local mean sea level or partial tides from the coast to open ocean due to a deepening bathymetry. Figure 3) a boxplot of the average HLC (Height of Living Coral) of living microatolls on all surveyed locations. n= the amount of surveyed individuals. Living Microatoll survey and HLC averages", "label": "poster"}
{"text": "FILM SERIES \u201cThe Human Dimensions of Climate Change\u201d Sponsored by: Fogler Library, the Climate Change Institute, Anthropology, Communication & Journalism & Political Science. The University of Maine does not discriminate on the grounds of race color, religion, sex, sexual orientation, including transgender status and gender expression, national origin, citizenship status, age, disability, genetic information or veteran\u2019s status in employment, education, and all other programs and activities. The following person has been designated to handle inquiries regarding nondiscrimination policies: Director, Office of Equal Opportunity, 101 North Stevens Hall, 207.581.1226. Discussant Dr. Robert Glover Assistant Professor of Political Science & Honors, Cooperating Faculty Margaret Chase Smith Policy Center This Changes Everything MARCH 29 @ 6PM Library Classroom, Fogler Library Merchants of Doubt MARCH 22 @ 6PM Library Classroom, Fogler Library Discussant Dr. Laura Rickard Assistant Professor of Communication and Journalism Discussant Dr. Daniel Dixon Research Assistant Professor, Climate Change Institute UMaine Sustainability In The Path of Resistance APRIL 5 @ 6PM Library Classroom, Fogler Library", "label": "poster"}
{"text": "CODATA-RDA Escuelas de Ciencia de Datos para la Investigaci\u00f3n Marcela Alfaro C\u00f3rdoba, Louise Bezuidenhout, Raphael C\u00f3be, Sara El jadid, Bianca Peterson, Rob Quick, Hugh Shanahan, Shanmugasun- daram Venkataraman Objetivos y Alcance \u2022 Crear una cultura dentro de las instituciones de investigaci\u00f3n de los pa\u00edses de ingresos bajos y medios, que se comprometa plenamente con la era de los Datos Digitales. \u2022 Escuelas regionales para ense\u00f1ar habilidades fundamentales de Ciencia de Datos, dise\u00f1adas para crear comunidades de personas investigadoras que inician su carrera en pa\u00edses de ingresos bajos y medios, que tienen inter\u00e9s en practicar la Ciencia Abierta. \u2022 Plan de estudios distribuido en dos semanas de clases. \u2022 Egresados incluyen m\u00e1s de 500 estudiantes de m\u00e1s 45 pa\u00edses. \u2022 Planes para futuras sesiones de formaci\u00f3n de formadores. Convocatoria abierta a ayudantes e instruc- tores para futuras escuelas regionales. Incorporaci\u00f3n de la Ciencia Abierta \u2022 Evitamos dar recetas. \u2022 Preparamos para la realidad en casa. \u2022 Promovemos el debate reflexivo. \u2022 Proveemos ejercicios \u00e9ticos integrados en cada sesi\u00f3n. \u2022 Mezclamos teor\u00eda con ejercicios pr\u00e1cticos. Curr\u00edculo Incorporamos la pr\u00e1ctica de la Ciencia Abierta en la formaci\u00f3n en CienciadeDatos. Tome una fotograf\u00eda para visitar nuestra p\u00e1gina web L\u00ednea de Tiempo \u2191 Julio 2016 \u2022 dataTrieste16 \u2022 ICTP Trieste, Italy Julio 2017 \u2022 dataTrieste17 \u2022 ICTP Trieste, Italy Diciembre 2017 \u2022 dataSaoPaulo17 \u2022 ICTP-SAIFR Sao Paulo, Brazil Julio 2018 \u2022 dataTrieste18 \u2022 ICTP Trieste, Italy Octubre 2018 \u2022 dataKigali18 \u2022 ICTP-EAIFR Kigali, Rwanda Diciembre 2018 \u2022 dataSaoPaulo18 \u2022 ICTP-SAIFR Sao Paulo, Brazil Junio 2019 \u2022 dataAddis19 \u2022 Addis Ababa University, Ethiopia Julio 2019 \u2022 dataTrieste19 and Data Stewards \u2022 ICTP Trieste, Italy Diciembre 2019 \u2022 dataSanJose19 \u2022 CeNAT San Jos\u00e9, Costa Rica Enero 2020 \u2022 dataPretoria20 \u2022 University of Pretoria South Africa Julio 2020 \u2022 dataTrieste20 \u2022 alumni meeting Online Enero 2021 \u2022 dataPretoria21 \u2022 University of Pretoria Online Septiembre 2021 \u2022 dataTrieste21 \u2022 ICTP, Trieste Online Mayo 2022 \u2022 dataPretoriaSaoPaulo22 \u2022 Pretoria and Sao Paulo Online Julio 2022 \u2022 dataTrieste22 \u2022 ICTP Trieste, Italy \u2022", "label": "poster"}
{"text": "The Heliocentric Model of Open Science Documentation Understanding Scientific Information Stewardship Top-Down and Bottom-Up v6 29NOV2024 Monica Gonzalez-Marquez, et al*, Open Science Advocate mg246@cornell.edu DOI: 10.5281/zenodo.14242541 1. Do away with a paper-centric model of documentation 2. Return to first principles and allow Scientific Questions and their constraints to guide documentation structure. 3. For optimal communication, allow the labor of the scientific process to determine: a. What needs to be documented b. How it should be documented Golden Rule: Documentation is for communication with humans The documentation tools we build are meant to serve the components of the scientific process, not exist independently: Data without its context is meaningless. Credit: T \u0160imko. METHODS METHODS *paper with collaborators forthcoming Scientific documentation should not be constrained by the limits of the out-of-date research article. Scientific information takes make shapes and model media should be used to accommodate it. The purpose of documentation is to Communicate our science to current and Future generations. Science is a verb, it is labor. RDM should be grounded in preserving Information about the labor that produced the data, as well as the data itself. Instead of allowing the paper and publishing constraints to dictate what information is documented for posterity and how, Helio positions the research question at the helm of record-keeping. It is in turn, constrained by the resources needed to ask the question. These two layers are constrained by the communicative drive: science that is not communicated in usable fashion, may as well not exist. It is also a complete waste of resources, and thus not sustainable. The methods satellite below shows some of the labor involved in completing the methods component of a human science study. These details are indispensable to understanding how to interpret and potentially reproduce a study. They are also indispensable to accurate peer review. Current documentation practices either grossly under-describe or completely omit these needed details. Helio provides needed structure to Open Science efforts by helping map tools, infrastructure and other resources directly to components of the scientific process, thus reframing them as being directly at the service of documenting complete research processes for posterity. Helio uses labor as the basic unit to breakdown scientific processes for documentation. These satellites are not mapped to sections in a paper but to components of scientific processes, as instantiations of the scientific method, and as the labor needed to complete them. This presupposes that scientific processes and their components will vary according to discipline. This model is an analogy of the original planetary model transition process. Just as it was an error to position the Earth at the center, it has been an error to place the paper at the helm of scientific documentation. It doesn\u2019t matter how sophisticated a machine learning algorithm might be or what A.I. can do, the ultimate interpreters of scientific information will always be people. Hence, we must document so that information is usable and understandable by people. \u00a9In\u00eas Silva for all figures unless otherwise noted The paper is demoted to become the narrative. In this way it assumes the role it has in practice which is to function as an extended abstract with links to detailed, usable descriptions of the labor and labor products of the scientific process.", "label": "poster"}
{"text": "Centro Universit\u00e1rio Euroamericano - UNIEURO / Curso de Medicina Humanidades M\u00e9dicas REDU\u00c7\u00c3O DE DANOS: USO DE PSICOESTIMULANTES POR ESTUDANTES DE MEDICINA 1Autores: MARIANA DIAS TEIXEIRA; NAT\u00c1LIA FERNANDES CAVALCANTI; NICOLE COSTA DE HOLANDA; VALENTINA DINIZ CATHOUD; PEDRO AUGUSTO M FERREIRA ; WESLEY RIBEIRO DE CASTRO 2 Orientadoras: VANESSA TEREZINHA ALVES TENTES; PROF\u00aa MS DIANA ARISTOTELIS ROCHA DE S\u00c1 INTRODU\u00c7\u00c3O O uso de psicoestimulantes, como o metilfenidato, tem se tornado comum entre estudantes de medicina, que recorrem a esses medicamentos para melhorar o desempenho acad\u00eamico, principalmente em situa\u00e7\u00f5es de alta press\u00e3o. No entanto, o uso indiscriminado sem prescri\u00e7\u00e3o m\u00e9dica levanta preocupa\u00e7\u00f5es s\u00e9rias sobre os efeitos colaterais e o risco de depend\u00eancia. Diante disso, a abordagem de redu\u00e7\u00e3o de danos emerge como uma estrat\u00e9gia fundamental para minimizar os impactos negativos dessa pr\u00e1tica, promovendo um uso mais seguro e informado dos medicamentos. OBJETIVO Este artigo busca discutir a aplica\u00e7\u00e3o de estrat\u00e9gias de redu\u00e7\u00e3o de danos relacionadas ao uso de metilfenidato por estudantes de medicina, com foco em minimizar os riscos \u00e0 sa\u00fade f\u00edsica e mental, al\u00e9m de fornecer suporte educacional e psicol\u00f3gico para esses indiv\u00edduos. M\u00c9TODO RESULTADOS A revis\u00e3o revelou que aproximadamente 23,3% dos estudantes de medicina recorrem a subst\u00e2ncias psicoestimulantes, como o Venvanse e o Ritalina, para superar a fadiga e melhorar o desempenho acad\u00eamico. Notavelmente, 57,1% desses indiv\u00edduos utilizam tais medicamentos sem prescri\u00e7\u00e3o m\u00e9dica ou diagn\u00f3stico formal, obtendo-os de forma il\u00edcita atrav\u00e9s de amigos, parentes ou receitas falsas. O uso de metilfenidato sem prescri\u00e7\u00e3o entre estudantes de medicina \u00e9 uma quest\u00e3o cr\u00edtica que exige interven\u00e7\u00e3o imediata. As estrat\u00e9gias de redu\u00e7\u00e3o de danos, quando aplicadas de forma eficaz, podem diminuir os riscos \u00e0 sa\u00fade e promover o bem-estar geral dos estudantes. \u00c9 essencial que as institui\u00e7\u00f5es de ensino m\u00e9dico implementem programas educacionais e de suporte que abordem as causas subjacentes ao uso desses medicamentos, proporcionando um ambiente acad\u00eamico mais saud\u00e1vel e seguro. REFER\u00caNCIAS Lopes, J. V. et al. (2024). Metilfenidato e Venvanse: o impacto na qualidade de vida dos estudantes de Medicina. Brazilian Journal of Implantology and Health Sciences, 6(8), 1891- 1906 Amaral, N. A. et al. (2022). Precisamos falar sobre uso de Metilfenidato por estudantes de medicina - revis\u00e3o da literatura. Revista Brasileira de Educa\u00e7\u00e3o M\u00e9dica, 46(2), e060 Santos, M. E. B. V. et al. (2022). Uso de metilfenidato e lisdexanfetamina por universit\u00e1rios da \u00e1rea da sa\u00fade: uma revis\u00e3o bibliogr\u00e1fica. Revista Corpus Hippocraticum, 2(1) CONSIDERA\u00c7\u00d5ES FINAIS Foi realizada uma revis\u00e3o de literatura em bases de dados como PubMed, Scielo e LILACS, com foco em estudos sobre o uso de metilfenidato entre estudantes de medicina sem diagn\u00f3stico de TDAH (Transtorno de D\u00e9ficit de Aten\u00e7\u00e3o e Hiperatividade). Foram analisadas pesquisas publicadas nos \u00faltimos cinco anos, que abordam tanto os efeitos do uso quanto as estrat\u00e9gias de mitiga\u00e7\u00e3o dos danos associados ao uso n\u00e3o supervisionado de psicoestimulantes A rotina dos estudantes de medicina \u00e9 marcada por alta carga de trabalho, longas horas de estudo, est\u00e1gios e prepara\u00e7\u00e3o para exames. Com isso, muitos estudantes recorrem a estimulantes como o Venvanse e a Ritalina, com a expectativa de melhorar a capacidade de concentra\u00e7\u00e3o, aumentar a produtividade e diminuir a fadiga mental e f\u00edsica.Esses psicoestimulantes agem inibindo a recepta\u00e7\u00e3o dos neurotransmissores, resultando em um aumento da concentra\u00e7\u00e3o extracelular de dopamina e norepinefrina. Contribuindo para a melhora dos sintomas associados ao TDAH, como a desaten\u00e7\u00e3o, hiperatividade e impulsividadeApesar dos benef\u00edcios percebidos, a efic\u00e1cia real desses medicamentos para indiv\u00edduos saud\u00e1veis, sem diagn\u00f3stico cl\u00ednico, \u00e9 questionada, com evid\u00eancias sugerindo que o efeito placebo pode desempenhar um papel significativo na percep\u00e7\u00e3o de mel", "label": "poster"}
{"text": "www.dtls.nl \u2022 https//www.helisacademy.com/en \u2022 A three year project targeting the Life Science & Health sector \u2022 Aim: Improve skills for both new staff and existing staff (lifelong learning) on identified gaps, by developing tailored training \u2022 Helis themes identified: Good manufacturing practices (GMP), Clinical testing, Business development, Product & process design, Data Analysis & Stewardship \u2022 Contact: celia.van.gelder@dtls.nl \u2022 https://zenodo.org/communities/nl-ds-pd-ls/ \u2022 Aim: professionalise the data steward function within the life-sciences domain, with a special focus on implementation of the FAIR principles and endorsed by all stakeholders in NL \u2022 First deliverable: Life Science Data Steward Function Matrix v1.1, for 2 levels of Data Stewards and 9 knowledge areas: https://zenodo.org/record/2561723 \u2022 Upcoming: defining competences and building training \u2022 Contact: celia.van.gelder@dtls.nl FAIR Data Training and Community Building activities in the Netherlands Mateusz Kuzak, Christine Staiger and Celia W. G. van Gelder (DTL/ELIXIR-NL) Interoperability, FAIR data stewardship and training researchers and data experts are themes that are core to the remit of DTL and ELIXIR Netherlands. In line with these focal points, a significant part of our DTL Learning/ELIXIR- NL training activities can be categorized as \u201cFAIR Data Training & Community Building\u201d. They are set up with and by the DTL and ELIXIR-NL Community in the Netherlands, and in close collaboration with the DTL Data and DTL Technologies programmes. A number of highlights are shown here, more information can be found at https://www.dtls.nl/fair-data/fair-data-training/. Community Building \u2013 The Data Stewards Interest Group Defining the Data Steward profession & Curriculum Building \u2022 https://ds-wizard.org/ \u2022 The Data Stewardship Wizard (DSW) is a web-based application for preparing smart Data Management Plans. It connects to additional learning resources and helps raise awareness about DS challenges. It can be customised by Data Stewards or Funders to meet more specific needs. \u2022 Contact: rob.hooft@dtls.nl Training in Data Analysis & Stewardship \u2022 https://www.dtls.nl/community/interest-groups/data- stewards-interest-group/ \u2022 A community hub for Data Stewardship that enables informal and inclusive knowledge and experience exchange. \u2022 Ca. 90 members (NL, BE, LU, UK, SE, FR, DE) \u2022 Mission: \u2022 Providing a platform for Data Stewards and like-minded in the Netherlands (and abroad) to share the experience \u2022 Fostering the national implementation of Data Stewardship \u2022 Joining efforts to produce hands-on solutions \u2022 Contact: Jasmin B\u00f6hmer (chair), j.k.bohmer@umcutrecht.nl Contact Celia van Gelder Programme Manager DTL Learning/ELIXIR-NL Training, celia.van.gelder@dtls.nl Mateusz Kuzak Scientific Community Manager DTL, mateusz.kuzak@dtls.nl Christine Staiger Data Steward DTL, christine.staiger@dtls.nl The ELIXIR Data Stewardship Wizard", "label": "poster"}
{"text": "ABSTRACT Hepatitis E virus (HEV) is a lesser-known hepatitis virus, but its worldwide spread is doubtless and has increased recent years. Zoonotic spread of HEV, mainly due to genotype (gt) 3, has emerged in developed countries in the past decade. The current study has shown for the first time that domestic pigs in Bulgaria are widely infected with HEV. There is a need for a method for the cost-effective detection of the HEV infection and production of HEV immunogenic proteins that can be used as diagnostic antigens for the serological tests. Also, in this study we have compared the results from a commercial ELISA and an in-house ELISA test based on HEV open reading frame (ORF) 2 protein produced in planta, the sensitivity and the specify of the tests were evaluated. The development of a HEV diagnostic kit based on plant-derived ORF2 capsid protein is our goal and this will help to reduce the cost of such a kit and to enable diagnoses of HEV in developing countries. Serological diagnostics of hepatitis E virus infection in pigs based on capsid protein (ORF2 genotype 3) expressed in planta \u2013 sensitivity and specificity Katerina Takova 1, Tsvetoslav Koynarski 2, Valentina Toneva 1, 3, Gergana Zahmanova 1, 4 Acknowledgements In total, 433 swine blood samples were collected from 19 different pig farms and 1 slaughterhouse, located in eleven districts across Bulgaria\u2014Pazardzhik, Plovdiv, Stara Zagora, Yambol, Ruse, Razgrad, Silistra, Shumen, Varna, Dobrich, and Burgas district. The samples were collected during 2017 (n = 75), 2018 (n = 158), and 2019 (n = 200). In 2018 samples were taken from two age-groups, 6- month-old pigs that weighed around 80\u2013100 kg (n = 78), and approximately 3- month-old pigs that weighed around 30 kg (n = 80). The samples taken in 2017 and 2019 are all from 6-month-old pigs. In addition, 32 meat chunks from wild boar were collected for meat juice extraction. The samples were collected from animals hunted in Stara Zagora, Vratsa, Montana, and Dobrich districts during the official hunting season. CONCLUSION: This study confirmed that plant-derived HEV diagnostic antigen could provide a cost-effective and scalable alternative of the commercially available coating protein. This research was funded by the Research Fund at the University of Plovdiv, competition \u201cYoung Scientists and Doctoral Students\u201d MU21-BF-02, the Bulgarian National Fund, Project DNTC/Russia 02-6, Project PlantaSYST. PlantaSYST has received funding from the European Union\u2019s Horizon 2020 research and innovation programme (SGA-CSA No 664621 and No 739582 under FPA No. 664620) Figure 1. The map of Bulgaria represents the districts of origin of the farming pigs tested in grey - Pazardzhik, Plovdiv, Stara Zagora, Yambol, Ruse, Razgrad, Silistra, Shumen, Varna, Dobrich, and Burgas district. The origins of the wild boar\u2019s testes are marked with red circles. Wild boar samples originated from Stara Zagora, Dobrich, Vratsa and Montana district. Figure 4. Determination of the optimal antigen concentration (recombinant capsid protein) for the developed ELISA. A two-fold dilution series of the recombinant capsid protein was performed to identify the optimum working concentration, and a titration experiment was performed using pig sera already with known serostatus. Results of the checkerboard titration analysis demonstrated that the most optimal and reliable results were obtained with coating protein concentration of 2 ng/ul. Figure 2. A A high HEV seroprevalence at all farms in 2019 \u2013 [98% (95% Cl 96.4 to 99.9)] compared to 2017 \u2013 [45.33% (95% CI 2.7 to 87.3)] and 2018 \u2013 [38.46% (95% CI 29.1 to 49.7) is observed. A significant year effect (2019) was found, p-value < 0.01 (Table 2). The chi-square statistic is 149.0211. The p-value is < 0.00001. The result is significant at p < 0.01. B Distribution of the observed within the farm seroprevalence of HEV among the slaughter-aged pigs (17 farms and 1 slaughterhouse with 30 % 2017- 2020, Bulgaria). The chart r", "label": "poster"}
{"text": "Potential Cost-saving for Liquid-to-Solid Medicines among Paediatric Patients Wei Chern Ang1,2, Mohamad Syafuan Fadzil2*, Chian Khie Lim2, Nur Inani Mohamad Nasir2, Muhammad Asyraf Amir2 1 Clinical Research Centre, Hospital Tuanku Fauziah, Ministry of Health Malaysia 2 Department of Pharmacy, Hospital Tuanku Fauziah, Ministry of Health Malaysia BR-08 NMRR-18-2790-44206 Introduction The World Health Organisation (WHO) recommends that children be treated with oral solid medicines for drugs, especially those require a precise dose titration.1 Problem statement: Factors that can affect a child\u2019s success in swallowing pills include developmental stage, fear, anxiety, intolerance of unpleasant flavors and failure to appreciate the risks associated with the non- compliance. Inadequate dosing flexibility without the need of tablet crushing explained the lack of usage of solid oral formulation in pediatrics.2 The current practices only based on preference of prescribers and patient\u2019s parent/care. Justification of Study: \u2022There are still lack of evidence regarding the solid oral formulation suitability in Malaysia \u2022 There is no published study in Malaysia that analyses the cost differences when oral liquid medications were changed to oral solid medications in a hospital outpatient setting. Objective: 1. To examine the association of demographic and solid dosage suitability. 2. To investigate factors affecting prescribing of solid oral dosage dorms. 3. To examine the potential cost savings if patient were prescribed with solid over liquid preparations. Methods This cross-sectional study conducted from October 2018 to March 2019 among patients visiting Paediatric Clinic, Hospital Tuanku Fauziah (HTF), Kangar, Malaysia. Discussions/Conclusions 1. WHO (2008). Report of the informal expert meeting on dosage forms of medicines for children. Geneva, Switzerland.15-6. 2. Patel A et al. (2014). J Pediatr. 135;183 3. EMA (2011) Guideline on Pharmaceutical Dev. of Medicines for Paediatric Use. 4. Lajoinie A et al. (2014). Br J Clin Pharmacol. 78(5); 1080-1089. 5. Jacobsen, L et al.(2016) Tablet/capsule size variation among the most commonly prescribed medication for children in the USA; 65-73. Variable Solid Dosage Suitability p-value Yes No Age (years) 2-5 6-11 >12 Weight (kg, adjusted by age) <13 >13.01 Race Malay Non-Malay Disease condition Acute Chronic Gender Male Female 107 (47.6) 50 (42.0) 10 (37.0) 97 (50.8) 70 (38.9) 162 (45) 5 (45.5) 153 (46.8) 14 (31.8) 96 (46.8) 71 (42.8) 118 (52.4) 69 (58.0) 17 (63.0) 94 (49.2) 110 (61.1) 198 (55) 6 (54.5) 174 (53.2) 30 (68.2) 109 (53.2) 95 (57.2) 0.425* 0.021* 0.976** 0.075** 0.463** References Variable Crude OR (95%CI) p-value Age (years) 2-5 6-11 >12 Weight (kg) Disease condition Acute Chronic Gender Male Female 1.00(ref.) 1.25(0.80,1.96) 1.54(0.67,3.51) 1.04 (1.01,1.07) 1.00 (ref.) 0.53 (0.27,1.04) 1.00 (ref.) 1.18(0.78, 1.78) 0.327 0.303 0.004 0.064 0.435 In conclusion, conversion of liquid to suitable oral solid medications is cost-saving and feasible to be practised. \u2022 Most tablets prescribed were in the range of 5-10mm (62.5%) which are only suitable for 6-11 years old.3 However, there is no significance difference between age group and solid dosage suitability (p>0.05). \u2022 Most of prescribed medication for paediatrics varied widely in size e.g. paracetamol 500mg tablets ranged from 5 to 22mm, with a median of 15mm. The common paediatric antibiotics were larger with a median diameter of 17mm).5 \u2022 Most of our paediatric patients were 2-5 years old (60.6%). However, only a fraction (15.1%) of tablet with size of 3-5mm were only suitable for this age group. Liquid formulation will still be suitable for this group of patients. In our setting, parents/carers may still be afraid for patients to take solid dosage medication in this age. \u2022 Suitability of oral solid dosage forms based on size from the EMA3 may not be suitable for Asian population. To the best of our knowledge, there is no consensus or g", "label": "poster"}
{"text": "Introduction Methodology Results Next steps References Acknowledgements A - Samples of di\ufb00erent insects (Honeybees, Solitary Bees and Bumblebees) were scanned in TIF format 16bit depth, 1920x1920 pixels. B - CT scans in Raw setup, without \ufb01ltering. In some cases was required in this process using python scripts (Figure 1). C - 3D model processed in the Blender 3D software, using automatic and manual tools for cleaning up (Figure 2). D - Model after cleaning up and with internal armature for rigging (Figure 3). E - Model in natural position, with wings \ufb01xed, ready to be exported. F - Render model made in Blender cycles for scienti\ufb01c illustration. G- Voxelized model in Sim4Life ready for simulations (3.5GHz, 20M cells). 25 CT scans were processed in to 3D models STL format, ready to be used in RF-EMF simulations. Models were tested for compatibility with Sim4Life software. For some models reconstruction of missing parts as such wings and legs were necessary. Those were done using references from literature. For manual tasks, python scripts using Blender API work\ufb02ows were created where was possible to automate the work. Scripts can generate simple structures like antennas and legs segments. [1] Thielens, et al. Scienti\ufb01c Reports 8(1), 3924, 2018. [2] Thielens, PE 690.021, 2021, doi: 10.2861/318352. - Insects are crucial for the sustainability of ecosystems. - Telecommunication antennas emit Radio-Frequency Electromagnetic Fields (RF-EMFs) that could a\ufb00ect insects. As telecommunications evolve (from 4G to 5G), the exposure of insects to RF-EMFs is likely to vary [1]. - Near powerful antennas, pollinators like bees face relatively high levels of RF-EMF exposure. This exposure can cause biological reactions in insects [2], yet the consequences of RF-EMF exposure on insects remain uncertain [2]. ETAIN has received funding from the European Union\u2019s Horizon Europe research and innovation program under grant agreement No. 101057216 To assess the absorption of RF-EMFs in insects by utilizing detailed anatomical 3D models derived from CT scans, and to develop adaptable models compatible with EMF simulation software for various simulation scenarios. In this poster we focus on the process of extracting CT scan data to 3D models. Conduct simulations across each model at frequencies (1.8, 3.5, and 26 GHz) to verify whole-body averaged absorbed power, speci\ufb01c absorption rates and absorbed power densities. This will facilitate the analysis of how the distinct shapes of insects in\ufb02uence the results of these simulations. Implement simulations on heterogeneous models by assigning varied dielectric properties to di\ufb00erent parts of the insects. This approach will enable a more detailed and accurate representation of real-world conditions. Additionally, undertake simulations that focus on the internal structures of insects, thereby providing deeper insights into the internal e\ufb00ects of RF-EMF exposure. By executing these steps, the project aims to shed light on the complex interactions between electromagnetic \ufb01elds and biological entities, o\ufb00ering valuable data for both scienti\ufb01c understanding and practical applications in the \ufb01eld of bioelectromagnetics. Goals Figure 3. Illustration of the processing method of a CT scan of Osmia bicornis. Figure 1. Bombus terrestris CT scan \ufb01ltering method. 1.1 - Raw CT scan \ufb01le. 1.2 3D model extracted from 1.1. The insect fur creates extra volume and issues to process the 3D model. 1.3 Filtered CT scan with lower density structures as the fur removed. 1.4 Updated 3D model without problematic fur meshes. Figure 2. 3D Models processing steps in Blender. Scripts have been implemented to streamline data aggregation into a uni\ufb01ed table, capturing species name, collection site, and date. Additionally, it compiles morphological metrics calculated in Blender alongside Sim4Life simulation parameters and outcomes, providing a consolidated view of each sample's characteristics and simulation data. 3D Models were created using C", "label": "poster"}
{"text": "Scientific Knowledge Graphs and Metadata Infrastructure Daan Broeder, Menzo Windhouwer, Michael Kurzmeier, Katja Moilanen CLARIN ERIC, KNAW/HuC-DI, OAEW, TAU-FSD Scientific Knowledge Graphs Scientific Knowledge Graphs (SKGs) have recently gained popularity as a rich metadata structure for describing research activities using triples. The idea that a fully connected graph better represents the real world than a hierarchical structure is now widely accepted. Current implementations are the OpenAIRE Research Graph, PID Graph (DataCite), Open Research Knowledge Graph (TIB), \u2026 OpenAIRE Graph data model Data Cite PID Graph content From Scholarly to Scientific Knowledge Graphs? Within the RDA WG SKG Interoperability Framework, some existing SKGs have been developing a standardised model for SKGs. However mainly from a perspective of publishing and measuring research output for funders. To better model the research process, entities and relationships involving data creation and processing, such as processing services and instruments, are needed The research communities collaborating in the OSTrails project are advancing this work in the SKG-IF WG. Metadata Interoperability: SKGs to the rescue? In the OSTrails project the creation of SKGs by communities is an important means for improving the Discoverability and Interoperability of the community resources. From the SSHOC science cluster a number of CLARIN, DARIAH and CESSDA partners closely collaborate. The SSHOC partners are working towards creating SKGs from their rich metadata catalogues: - CESSDA data catalogue (CDC) - CLARIN Virtual Language Observatory (VLO) - SSH Open Marketplace (SSHOMP) Existing SKG-IF model SSHOC science cluster use-cases Retrieve information from SKGs : 1.When a user creates a new item in the SSHOMP, users enter the PID and fields for the new item are populated with the results. 2.When a user visits a dataset in the VLO see if the creator has also resources in the CESSDA SKG. Metadata catalogue Metadata Repository SKG publishing JSON / RDF / \u2026 OAI-PMH +? JSONAPI + SPARQL + .. Std. vocabularies community metadata providers OAI-PMH + ? Metadata catalogue Metadata Repository SKG publishing JSON / RDF / \u2026 OAI-PMH +? JSON API + SPARQL + .. Std. vocabularies community metadata providers OAI-PMH + ? SKG based Information exchange SKGs exchanging information", "label": "poster"}
{"text": "Kosuke Namekata (National Astronomical Observatory of Japan, e-mail: kosuke.namekata@astro.nao.ac.jp)1 Hiroyuki Maehara1; Satoshi Honda2, Yuta Notsu3; Daisaku Nogami4; Kazunari Shibata4, and SMART & OISTER team collaborations (1) National Astronomical Observatory of Japan (NAOJ); (2) University of Hyogo; (3) Colorado University; (4) Kyoto University A Filament Erup/on and Coronal Mass Ejec/on from a Super\ufb02are on a Young Sun-like Star We report that our op*cal spectroscopic observa*on of the young solar-type star EK Draconis reveals the \ufb01rst evidence for a stellar \ufb01lament erupCon associated with a super\ufb02are on a young Sun-like star EK Draconis (Namekata et al. 2021 (or 2022), Nature Astronomy, 6, 241). We monitored EK Draconis for about 30 nights with the TESS\u2019s op*cal photometry and ground-based spectroscopy, and \ufb01nally detected a super\ufb02are in white-light and H\u03b1. APer the super\ufb02are with radiated energy of 2.0x1033 erg, a blue-shiPed H\u03b1 absorp*on component with a large velocity of -510 km s-1 appeared. The temporal changes in the spectra greatly resemble the Sun-as-a-star spectra of solar \ufb01lament erup*ons, indica*ng a common picture of solar and stellar \ufb01lament erup*ons. The comparison of this stellar \ufb01lament erup*on with solar \ufb01lament erup*ons in terms of the length scale and velocity strongly suggests that this would eventually become a stellar CME. The mass of erupted \ufb01lament of 1.1x1018 g is surprisingly 10 *mes larger than those of the largest solar CMEs. The huge \ufb01lament erup*on and an associated CME on the young Sun-like star provide the \ufb01rst opportunity to evaluate how the young Sun-like star/young Sun a\ufb00ects the environment of young exoplanets/young Earth as well as stellar mass/angular-momentum evoluCon (cf. the faint young Sun paradox). 1. Introduc,on 3. Filament erup,on on young Sun-like star 2. Observa,ons 4. Sun-as-a-star analysis 5. Frequency of CMEs 7. References 6. Summary & Future Works 1. Namekata et al. 2021 online (or 2022a), Nature Astronomy, 6, 241(\u2192) 2. Namekata et al. 2022b, ApJ Le?ers, 926,5 3. Namekata et al. 2022c, accepted (h?ps://arxiv.org/abs/2206.01395) [See, my talk in Splinter session \u201cSolar and stellar coronal mass ejecOons\u201d ] FIGURE 3: A solar \ufb02are WITH \ufb01lament erupOon. (middle) Light curve. (right) Dynamic spectrum of the H\u03b1 line (Namekata et al. 2021 (or 2022a), Nat. Astron.). What does the erup5ve event on EK Dra look like? To answer this quesOon, we conducted the Sun-as-as-star analysis of H\u03b1 spectrum of solar \ufb01lament erupOons. As a results, spectral features are very similar to the event on EK Dra, indicaOng that the event on EK Dra was a large-scale \ufb01lament erup5on whose picture is similar to those of solar \ufb01lament erup5ons. Solar image H\u03b1 \u2013 1\u212b \ufb01lament \ufb02are FIGURE 4: A solar flare WITHOUT a signature of filament eruption. In this case, strong redshifted & broadened spectrum can be seen (Namekata et al. 2022c, ApJ). \ufb02are Velocity [km/s] Wavelength [\u212b] Impulsive Phase (\ufb02are) Normalized Intensity Decay phase FIGURE 1: A stellar \ufb01lament erupOon from a 2x1033 erg super\ufb02are on a young Sun- like star EK Dra. (le`) Light curve in H\u03b1. (middle) pre-\ufb02are subtracted spectrum (right) Dynamic spectrum (Namekata et al. 2021 (or 2022a), Nat. Astron.). We detected H\u03b1 spectra from superflares (1033-34 erg) on a young Sun-like stars for the first time. Surprisingly, one of them shows post-flare H\u03b1 dimming, and the H\u03b1 spectrum shows blue-shifted absorption component. We concluded that we detected a stellar filament eruption on young Sun-like star for the first time. FIGURE 2: Large velocity and length scale indicate that the \ufb01lament erup5on eventually becomes stellar CMEs. ProperOes Velocity: -510 km/s Length scale: 500 Mm Mass: 1.1x1018 g (10 x the largest solar CME) Super\ufb02are FIGURE 5: NO \ufb01lament erup5on signature in a 1034 erg super\ufb02are on a young Sun- like star EK Dra. (Namekata et al. 2022b, ApJ Le?ers). Other super\ufb02ares DO NOT necessarily show \ufb01lament erup5on signatures \u21d2Signatures of \ufb01lament erupOon", "label": "poster"}
{"text": "Innovation Radar INCUBATOR HUB www cincubator.com @CincubatorHUB @cincubator @CloudIncubatorHUB", "label": "poster"}
{"text": "Acknowledgements & Computational Resources References [1] Tan C. and McClements D. J., Foods , Apr. 2021, vol. 10, no. 4, p. 812 [2] Bai L., Huan S., Rojas O. J., and McClements D. J, J. Agric. Food Chem., Aug. 2021, vol. 69, no. 32, pp. 8944\u20138963. [3] Posocco P., Perazzo A., Preziosi V., Laurini E., Pricl S., and Guido S., RSC Adv., 2016 vol. 6, no. 6, pp. 4723\u20134729. [4] Yamashita Y., Miyahara R., and Sakamoto K., Cosmetic Science and Technology, Elsevier, 2017, pp. 489\u2013506. [5] \u00c1lvarez Vanegas M. et al., J Mol Model, Dec. 2013, vol. 19, no. 12, pp. 5539\u20135543. Methodology Stability and Interfacial Phenomena of W/O Emulsions via Molecular Dynamics Lu\u00eds G. G\u00f3mez Mart\u00ednez1,4, Deisy G. Giraldo3,4, Marianny Y. Combariza2,5, Cristian Blanco Tirado2,5 & Aldo F. Combariza1,4 1 Departamento de Biolog\u00eda Y Qu\u00edmica, Facultad de Educaci\u00f3n y Ciencias, Universidad de Sucre. 2 Escuela de Qu\u00edmica, Facultad de Ciencias, Universidad Industrial de Santander (UIS). 3 Institut des Sciences Analytiques et de Physico-chimie pour l\u2019Environnement et les Mat\u00e9riaux, Universit\u00e9 de Pau et des Pays de l\u2019Adour. 4 Grupo de Investigaci\u00f3n en Modelamiento Molecular y Simulaci\u00f3n Computacional In silico, Universidad de Sucre. 5 Grupo de Investigaci\u00f3n en Fisicoqu\u00edmica Te\u00f3rica y Experimental GIFTEX, Universidad Industrial de Santander. e-mail: luis.gomez@unisucrevirtual.edu.co , aldo.combariza@unisucrevirtual.edu.co We thank to Universidad de Sucre and Universidad Industrial de Santander for the support and in-silico & GIFTEX Research Group members for their support in the development of this work. We thank to QCC organizing committee for the opportunity to participate in this event. We thank to IAAPP for allowing us the access to INKARI cluster and to Ronald Apaza for his support. We also thank to Dr. Wilson Castro Silupu and Ronald Apaza for allowing us the link to INKARI. Motivation Results and Discussion Preliminary Conclusions Phospholipidic Emulsifier 1-Palmitoyl-2-oleoyl -sn-glycero-3-phosp hocholine (POPC) 1-palmitoyl-2-oleoyl-3-stearoyl-glycerol (POS) 1-palmitoyl-2-oleoyl-3-stearoyl-glycerol (POS) 1,3-Dipalmitoyl-2-oleoylglycerol (POP) 1,3-distearoyl-2-oleoylglycerol (SOS) Main triacylglycerols (TAGs) and Phospholipids present in Theobroma cacao L. Kirkwood-Buff simplified formulation Theoretical Interfacial tension (IFT) of Commercial and Cocoa Emulsions ( mN m) IFT \u03b3 of Pattern Commercial Emulsion: 2.74 mN m IFT \u03b3 of Pattern Cocoa Emulsion: 1.98 mN m Experimental IFT \u03b3 of Oil (Sunflower) and Water: 24.80 In which we consider the tangential componentes (Pt = Pxx + Pyy)/2) and the normal component (PN = Pzz) to the interfacial plane of Cauchy Stress Tensor. Water in Oil (W/O) Emulsion Oil in Water (O/W) Emulsion Mix Emulsification CHARMM-GUI Effective Simulation Input Generator and More Automated Topology Builder (ATB) and Repository Visual Molecular Dynamics Phosphatidylcholine (PC) Phosphatidylethanolamine (PE) Phosphatidylserine (PS) Phosphatidylglycerol (PG) Phosphatidylinositol (PI) Phosphatidic acid (PA) Temperature: 298 K Pressure: 1 Bar Force Field: CHARMM36 Statistical Ensemble: NVT (for minimization) & NPT (for equilibration and production simulations) GROMACS Version: 2019.3 Water Model: TIP3P Finally we run a simulation of production of 50 ns, NPT ensemble, under normal conditions of pressure and temperature Then we run a minimization of 10.000 nsteps (step size 2fs, 20 ps) within the NVT ensemble and six different equilibrations of 125.000 nsteps (250 ps) NPT ensemble under normal conditions of pressure and temperature Analysis of MD Trajectories System setup CHARMM-GUI TAG\u2019s Topology files of molecules We select/download the TAG\u2019s topology files (SOS and POP) from the ATB repository to set up the simulation cell \u25cf MD simulations and trajectories showed that initial system of cocoa emulsions (with pure components) were well-equilibrated and the IFT values were ranged between 1-10 mN/m which are good values for emulsions. \u25cf RDF graph showed pea", "label": "poster"}
{"text": "Contact us now info@csem.ch \u2022 www.csem.ch Developing high-performance and safe electrolyte for silicon and lithium metal batteries Sufu Liu, Leonardo Pires Da Veiga, Chengyin Fu, Mohammed Srout, Andrea Ingenito CSEM Sustainable Energy Center, CSEM SA, Switzerland In-situ thermally triggered polymer for silicon battery electrolyte Abstract: Compared with the state-of-the-art graphite anodes, silicon and lithium metal are considered as the most promising alternatives for higher energy density lithium batteries owning to their high theoretical capacity. However, significant challenges such as low coulombic efficiency, short cycle life and safety concern have seriously hindered their practical applications. [1,2] To enable the use of silicon anode, we are developing a polymer electrolyte with self-healing properties to stabilize the electrode interphase and restrain the huge volume change of silicon material. When compared with commercial carbonate liquid electrolyte with or without additives, our designed polymer electrolyte enables the NMC622//Si full cell with improved capacity retention and combustion resistance. Meanwhile, for rechargeable lithium metal batteries, our designed nonflammable electrolyte also enables the LFP//ultra-thin lithium metal (25 \u00b5m) with greatly extended cycling life, which delivers more than 88% capacity retention after 400 cycles. Our research paves the way for safer and more efficient lithium-ion batteries with silicon or lithium metal-based anodes, which will help to realize higher energy density and longer-lasting battery technologies. Conclusion and future work \u2022 In-situ thermally triggered polymerization is a promising method for fabricating polymer electrolyte with self-healing properties outperforming the commercial carbonate electrolyte. \u2022 Electrolyte engineering with aggregate and contact ion pair structures is an effective strategy to develop advanced electrolyte with high Li metal Coulombic efficiency. \u2022 Thermally evaporated thin Li metal and advanced electrolyte design could be an effective combination to promote long-term cycling of lithium metal batteries. References: [1] Park et al., Chem. Sci., vol. 14, pp. 9996-10024, (2023). [2] Narayan et al., Adv. Energy Mater. vol. 12, pp. 2102652, (2022). Advanced electrolyte for lithium metal battery \u2022 99.6% Li Coulombic efficiency could be reached in the obtained electrolyte The mechanism diagram of in-situ polymerization of the thermally triggered polymer The structure design of the advance electrolyte for LMBs \u2022 Thermally evaporated Li metal with high purity \u2022 88% capacity retention after 400 cycles has achieved when coupling the in-home prepared ultrathin Li anode with commercial LFP cathode 60% Si coin cell exhibits enhanced capacity retention 20% SiOx punch cell indicates stable cycling Building more reliable and performing batteries by embedding sensors and self-healing functionalities to detect degradation and repair damage via advanced Battery Management Systems Methodology \u2022 Develop self-healing battery materials and sensing devices. \u2022 Validate the triggering mechanisms and degradation detection. \u2022 Assess the manufacturing, recycling, and sustainability process and develop the Battery Management System. Consortium", "label": "poster"}
{"text": "ENRICHING THE EVIDENCE BASE OF CO-CREATION IN PUBLIC HEALTH WITH METHODOLOGICAL PRINCIPLES OF CRITICAL REALISM INTRODUCTION Meta-theory, such as Critical Realism (CR) provides a foundation for understanding and researching phenomena. CR, originating from Bhaskar's work, distinguishes between the real and observable world and encourages exploring complex social phenomena with a focus on causal mechanisms. Co-creation research lacks explicit meta-theoretical foundations, whereas CR is a convincing proponent for hypothesised mechanisms to have the strongest explanatory power, related to empirical evidence. This study aims to explore critical realism as a promising meta-theory providing clear methodological principles [1,2] to enrich the evidence base for co-creation in public health research. RESULTS + MAIN TAKE-HOME MESSAGES www.healthcascade.eu @health_cascade Health CASCADE is a Marie Sk\u0142odowska-Curie Innovative Training Network funded by the European Union\u2019s Horizon 2020 research and innovation programme under Marie Sk\u0142odowska-Curie grant agreement n\u00b0 956501 AUTHORS: MESSIHA, K (1); ALTENBURG, TM (1); SCHREIER, M (2); LONGWORTH, GR (3); THOMAS, N (4); CHASTIN, S (5,6); CHINAPAW, MJM (1) Critical realism methodological principles seem well-suited as a meta-theoretical framework for evidence-based co-creation in public health empirical research METHODS Scan me to connect on LinkedIn Free hand Google Scholar Litmaps Full text screening Formative synthesis output Deliberative meetings Summative synthesis output Assessing applicability and usability (real-life case study \u201cKiA\u201d* [3] + WP3-6 feedback) Figure: Information flow chart of paper selection Define event as an outcome of research; Review literature for concepts, studies, and evidence; Provide chronological narrative; Analyse co-creators' perspectives; Compile key components: Actors, Actions, Objects, Outcome. Explication of Events Identification of + detailing the critical/ important events as a set of related actions or changes that occur over time and have a particular outcome or goal. Identify + analyse the components of the contextual environment that influence the event. Clarify their connections in order to understand how such event is influenced. Explication of structure + context Identification of social (norms) + physical structure, contextual environment + their relationships as linked to the event(s) which occurred. Propose superior mechanisms for event explanation; Identify contextual entities, including affordances influencing behaviours; Note retroduction's has 4 types: overcoded, undercoded, creative + meta-retroduction. Retroduction Identification + explanation of underlying mechanisms that caused the observed events. Formulate hypothesis based on prior knowledge; Test using empirical methods, longitudinally; Analyse data for variable relationships; Evaluate results for empirical adequacy; Further assess to corroborate/ refute refined theories. Empirical corroboration About the validation/ \u2018confirmation\u2019 of proposed causal mechanisms through empirical testing. Use diverse theories, methods, data sources + investigators for comprehensive perspectives; Assess event analysis significance (non-definitive). Triangulation and multi-methods About using (i.e., combining and integrating) a variety of data types and sources, relevant theories, analytical methods + observers in a research study to identify causal relationships. Principle 1 Principle 2 Principle 3 Principle 4 Principle 5 CR Principles with convincing empirical parallels to KiA... Event: Childhood overweight (outcome). Explored literature and local data (KiA neighbourhood). Participatory Assessment: 3-4 group meetings (children, n=20), interviews with parents (n=27), professionals (n=9). Results: Childhood overweight identified as main issue, with insufficient physical activity and unhealthy diet as main risk factors. Actions: Unhealthy behaviours. Objects: School, home, neighbourhood. Needs assessment w", "label": "poster"}
{"text": "The breakdown of current gyrochronology as evidenced by old coeval stars Diego Godoy-Rivera(\u2605), Joaqu\u00edn Silva-Beyer, Julio Chanam\u00e9 \u2022 Gyrochronology promises to deliver stellar ages for field main-sequence stars from rotation period measurements. \u2022 Before being widely used, the age- rotation relations must be comprehensively examined. \u2022 We develop a new method to test the state-of-the-art gyrochronology relations with old coeval stars. \u2022 In Figure 3, the members of Clusters show a better agreement with gyrochronology (highest peak), followed by the Wide Binaries. \u2022 We use Random Pairs as a control sample to calibrate the expected agreement for unassociated stars (assembled by disassociating the binary components). \u2022 The Random Pairs show a distribution in agreement with theoretical expectations (Expected \u0394Prot) \u2022 Our results demonstrate that the gyrochronology relations under study (Angus+19, Spada & Lanzafame 2020) do have predicting power, as the sets of coeval stars (Clusters, Wide Binaries) are in better concordance than the unassociated Random Pairs. \u2022 In Figure 4, we test the fractional agreement with gyrochronology as a function of age by using the different samples. \u2022 We find a good agreement for young ages (\u2272 1 Gyr) , but a clear degradation towards older ages (\u2273 2 Gyr). \u2022 This highlights the need for novel empirical constraints at older ages, which may allow revised gyrochronology calibrations. Fig. 2: Prot vs. color diagram for open clusters (top) and wide binaries (bottom). Silva-Beyer, Godoy-Rivera & Chanam\u00e9 (2023) Fig. 4: Agreement of gyrochronology as a function of age, for the different samples. Context Results Conclusions References Fig. 1: Illustration of the rotation period test \u0394Prot,gyro (top), and examples of low and high \u0394Prot,gyro values (bottom). Fig. 3: Normalized distribution of \u0394Prot,gyro values for the different data samples. More centrally concentrated peaks mean better agreement with gyrochronology. Gyrochronology relations: \u2022 Angus et al. (2019) \u2022 Spada & Lanzafame (2020) Data sets: \u2022 Curtis et al. (2020) \u2022 Godoy-Rivera et al. (2018, 2021b) \u2022 Gruner & Barnes (2020) \u2022 Meibom et al. (2015) (\u2605) diego.godoy.rivera@iac.es Method and Data For a given pair, it is the difference of Prot(expected)-Prot(measured) for the secondary given the primary\u2019s gyrochrone fit \u2022 In Figure 1, we design an indicator that quantifies the (dis)agreement between coeval pairs and a given gyrochronology relation. \u2022 We run the test using samples of stellar pairs with coeval, rotating components, for a range of ages. \u2022 These correspond to open clusters and Kepler-field wide binary systems, as shown in Figure 2. Gyrochronology relation = Spada & Lanzafame (2020) Fraction of each sample with |\u0394Prot,gyro| \u2264 N*\u03c3 \u0394Prot,gyro For more details, please see:", "label": "poster"}
{"text": "IMPORTANCE OF OCEAN HEAT CONTENT TO THE GLOBAL CLIMATE SYSTEM Eileen Maturi1, David Donahue2, Deirdre Bryne1 1. NOAA/NESDIS/STAR 2. NOAA/NESDIS/OSPO Ocean Heat Content (OHC) The Ocean Heat Content is a measure of the integrated vertical temperature from the 26o C isotherm to the sea surface where surface boundary conditions exist (area under the curve in Fig. 1). The 26o C isotherm defines the lower limit at which convection can develop and strengthen. Surface winds generate turbulent mixing within the uppermost part of the ocean; this layer is called the Mixed Layer, and can often reach depths of hundreds of meters. Turbulence associated with the Mixed Layer is responsible for providing a large reservoir of heat energy that can be tapped into by a tropical cyclone. This can intensify and extend the lifetime of the cyclone. Figure 1. Schematic of OHC calculation. The red shading shows the true OHC by integrating the black temperature profile. The dashed blue line shows the approximated temperature profile of the upper ocean. Summary The Madden Julian Oscillation (MJO) and the El Nino/La Nina oscillations have global impacts which affect all the basins. It is important to know the Ocean Heat Content of all the Ocean Basins to predict the rainfall patterns, tropical and mid-latitude cyclones and drought. All these phenomena are components of the Global Climate System. NOAA/NESDIS generates a daily suite of satellite-generated OHC products for the Atlantic and Pacific. There are plans to generate a suite of OHC products for the Indian Ocean. Operational Ocean Heat Content (OHC) Products IMPACTS \u2022 The OHC products are important to the monitoring and understanding of Coral Reef systems. Coral reefs are sensitive to unusually warm water. Increased Ocean Heat leads to the destruction of Coral Reefs. \u2022 Higher oceanic heat content leads to increased rainfall, which is beneficial for agriculture. \u2022 Increased oceanic heat content in the Northern Indian Ocean leads to increased summer monsoon rainfall in India. \u2022 Improved ecological forecasting leads to better management of fish stocks, which are an important food source for ocean-bordering countries. There is only one true ocean, the \u201cWorld Ocean.\u201d For simplicity, the World Ocean is divided into 5 interconnected ocean basins. They are the Atlantic, Pacific, Indian, Arctic, and Southern Oceans. Climatic Variability The Indian Ocean is the warmest of the 5 ocean basins. An Indian OHC product can provide information about the Madden Julian Oscillation (MJO), which is a major factor in determining rainfall, drought, and tropical cyclone patterns in the Eastern Hemisphere. MJO can be visualized as alternating regions of rising air and sinking air. The rising air is associated with tropical rainfall. The sinking air is associated with drier conditions, allowing more solar insolation to reach the ground, inducing drought. It can also play a role in strengthening or weakening tropical cyclones. In addition, the OHC can be used to gauge the strength and duration of the Indian, Asian and North American Summer Monsoons. The MJO typically moves across the tropical Indian Ocean and western Pacific before weakening; though it occasionally circumnavigates the global tropics in 30- 60 days (1-2 months). MJO differs from El Nino/La Nina primarily in that the MJO recurs more frequently (lasting 1-2 months),compared to El Nino/La Nina which recurs less frequently (lasting 6-9 months or longer). The OHC is especially important for the Atlantic and Pacific Basins to help gauge the intensity and duration of El Nino/La Nina, tropical and extratropical (mid- latitude) cyclones, and anomalous rainfall patterns.", "label": "poster"}
{"text": "Thibault Goessel*1,2, Simon Ligier1, Ad\u00e9la\u00efde Aublet-Mailhac1, Robin Girard2 / CONTEXTE ET OBJECTIFS Contexte \u2022 Le secteur du b\u00e2timent repr\u00e9sentait 25% de l\u2019empreinte carbone de la France en 2019. Les \u00e9missions de carbone sont r\u00e9parties sur toute la cha\u00eene de valeur : environ 2/3 pour la phase d\u2019exploitation du b\u00e2timent et 1/3 pour la phase de construction et fin de vie [1]. 1) D\u00e9velopper une m\u00e9thode d\u2019identification des strat\u00e9gies de r\u00e9novation optimales, bas\u00e9e sur l\u2019\u00e9valuation des impacts sur le cycle de vie du b\u00e2timent r\u00e9nov\u00e9. 2) Analyser l\u2019influence du r\u00e9chauffement climatique sur l\u2019identification des strat\u00e9gies de r\u00e9novation. / R\u00c9SULTATS \u2022 La massification de la r\u00e9novation du parc existant appara\u00eet comme un levier majeur de d\u00e9carbonation. Des objectifs nationaux ambitieux ont \u00e9t\u00e9 \u00e9tablis, comme l\u2019atteinte en moyenne pour le parc d\u2019ici 2050 du niveau B\u00e2timent Basse Consommation [2]. Il faudrait 700 000 \u00e0 1 million de r\u00e9novations performantes par an, contre 66 000 en 2022 [3]. \u2022 Des crit\u00e8res compl\u00e9mentaires existent pour juger de la performance d\u2019une r\u00e9novation. Plusieurs \u00e9tudes ont commenc\u00e9 \u00e0 analyser l\u2019influence du choix des crit\u00e8res sur les choix des strat\u00e9gies de r\u00e9novation, en se focalisant principalement sur le co\u00fbt et les \u00e9missions de gaz \u00e0 effet de serre [4,5]. La prise en compte du confort est plus r\u00e9cente [6]. [1] Feuille de route d\u00e9carbonation du b\u00e2timent, 2023 [2] Plan r\u00e9novation \u00e9nerg\u00e9tique des b\u00e2timents, 2021 [3] Rapport activit\u00e9 Anah, 2022 [4] Amini Toosi et al., 2020, \u00ab Life Cycle Sustainability Asssment in Building Energy Retrofitting : A Review \u00bb [5] Galimshina et al., 2021, \u00ab What Is the Optimal Robust Environmental and Cost-Effective Solution for Building Renovation? Not the Usual One \u00bb [6] Mostafazadeh et al., 2023, \u00ab Energy, economic and comfort optimization of building retrofits considering climate change: A simulation-based NSGA-III approach \u00bb [7] Kraiem et al., \u00ab fTMY-Documentation \u00bb, confidentiel [8] DGEC, 2023, \u00ab Synth\u00e8se du sc\u00e9nario \u00ab avec mesures existantes \u00bb 2023 de la Strat\u00e9gie Nationale Bas Carbone \u00bb \u2022 Etude de cas sur une maison individuelle : bloc b\u00e9ton, \u00e0 effet Joule, toit l\u00e9g\u00e8rement isol\u00e9, en Gironde (zone H2c), Cep=676 kWh/m\u00b2/an. \u2022 800+ strat\u00e9gies de r\u00e9novation m\u00ealant les lots techniques : chauffage, refroidissement, ventilation, murs, toiture, fen\u00eatres. \u2022 Taux d\u2019actualisation de 3,2 %. M\u00e9thodologie prospective pour l\u2019optimisation multicrit\u00e8re de la r\u00e9novation \u00e9nerg\u00e9tique des b\u00e2timents Objectifs CONF\u00c9RENCE IBPSA FRANCE 13 AU 17 MAI 2024 LA ROCHELLE ET OL\u00c9RON THIBAULT.GOESSEL@CSTB.FR 1 Centre Scientifique et Technique du B\u00e2timent (CSTB) 2 Mines Paris \u2013 PSL, centre PERSEE Th\u00e8se commenc\u00e9e le 21/11/2022 / M\u00c9THODOLOGIE \u2022 12 strat\u00e9gies sont sur le front de Pareto 3D (co\u00fbt, carbone, inconfort thermique) : \uf0d8 L\u2019int\u00e9gralit\u00e9 r\u00e9nove le syst\u00e8me de chauffage (chaudi\u00e8re bois) et isole les murs (ITE fibre de bois 24cm). \uf0d8 La moiti\u00e9 r\u00e9nove la ventilation (ventilation double flux). \u2022 La prospective climatique en ann\u00e9e-type aggrave l\u2019inconfort thermique (+200 \u00e0 +400 \u00b0C.h) mais a des effets marginaux sur le co\u00fbt total et l\u2019empreinte carbone. \u2022 Le choix des strat\u00e9gies optimales n\u2019est que peu modifi\u00e9 par la prospective climatique : parmi les 12 strat\u00e9gies sur le front de Pareto 3D en climat historique, 11 sont encore optimales en climat prospectif.", "label": "poster"}
{"text": "Extraction of historical information using semantic techniques and knowledge graphs Jorge \u00c1lvarez Fidalgo Introduction In the framework of the Semantic Web, knowledge graphs such as Wikidata have emerged as powerful tools to represent and or- ganise large amounts of information in a structured way (linked data). Our aim is to create a methodology that enhances the extraction of information from digitised historical documents by relying on external knowledge graphs, feeding them back in the process. Research questions \u2022RQ1. How can we extract linked data from historical documents? \u2022RQ2. Is it possible to use data from external knowledge graphs to improve the extraction process? \u2022RQ3. Is it possible to detect errors and shortcomings in external graphs from the extracted information? \u2022RQ4. How can we use NLP techniques to improve the accuracy of the linked data obtained? Methodology \u2022To solve RQ1, we extract triples (?head, ?rel, ?tail). \u2022In order to get all ?head -and some ?tail- entities we perform NER using existing M-BERT [1] derived models. \u2022To extract ?rels we propose to perform link prediction on Wikidata in two phases -thus addressing RQ2-. Link Prediction (I). Semi-inductive prediction [2] using tail prediction models trained on Wikidata datasets, such as KGT5 [3]. To restrict the number of properties to be predicted, we use Shape Expressions [4]. Link Prediction (II). Fully inductive prediction [2] in which, based on the information extracted in (I), we define property paths in Wikidata -by means of SPARQL queries- that, if they exist between two entities, indicate a possible relationship between them. Preliminary results To evaluate this approach we are applying these techniques on a corpus of Spanish medieval notarial records consisting of 128 documents [5]. We focus on three types of relationships of varying difficulty for their detection: father-child, spouse and sibling, obtaining high recall [0.60-0.87] yet very low accuracy ([0.06-0.08]). Preliminary conclusions \u2022Most of the relevant triples are extracted successfully. \u2022Those undetected are mostly due to a) incomplete information in the knowledge graph (RQ3) and b) relationships that do not adhere to any pattern. \u2022Accuracy is very low since many non-relevant pairs of entities match the patterns. \u2022RQ4 may be of help in this regard, thus facilitating the work of the human-in-the-loop. Bibliography [1] Telmo Pires, Eva Schlinger, and Dan Garrette. How multilingual is multilingual BERT? In Proceedings of the 57th Annual Meeting of the Association for Computational Linguistics, pages 4996\u20135001, Florence, Italy, July 2019. Association for Computational Linguistics. doi: 10.18653/v1/P19-1493. [2] Mehdi Ali, Max Berrendorf, Mikhail Galkin, Veronika Thost, Tengfei Ma, Volker Tresp, and Jens Lehmann. Improving inductive link prediction using hyper-relational facts. In The Semantic Web \u2013 ISWC 2021, pages 74\u201392, Cham, 2021. Springer International Publishing. ISBN 978-3-030-88361-4. [3] Apoorv Saxena, Adrian Kochsiek, and Rainer Gemulla. Sequence-to-sequence knowledge graph completion and question an- swering. In Proceedings of the 60th Annual Meeting of the Association for Computational Linguistics, pages 2814\u20132828, 01 2022. doi: 10.18653/v1/2022.acl-long.201. [4] Eric Prud\u2019hommeaux, Jose Emilio Labra Gayo, and Harold Solbrig. Shape expressions: an rdf validation and transformation language. In Proceedings of the 10th International Conference on Semantic Systems, SEM \u201914, page 32\u201340, New York, NY, USA, 2014. Association for Computing Machinery. ISBN 9781450329279. doi: 10.1145/2660517.2660523. [5] Jorge Felpeto Cueva and Calleja Miguel Puerta. El archivo de un artesano del siglo XIV: el orfebre Alfonso Fern\u00e1ndez de Oviedo. Phd thesis, Universidad de Oviedo, 2023.", "label": "poster"}
{"text": "I. Motivation IV. Results & Discussion Jason N. Ott1*, Cailey B. Condit1 and Vera Schulte-Pelkum2 1University of Washington, Earth and Space Sciences, Seattle WA 2University of Colorado Boulder, Boulder CO *jasonott@uw.edu Seismic Anisotropy of Mafic Blueschists: Constraints from Exhumed Glaucophane-Rich Blueschists with Implications for the Subduction Interface Diagram of a typical subduction zone illustrating major structural features and the evolution of pressure and temperature with increasing depth. II. Materials \u2022 Samples selected from naturally deformed, mafic blueschists with variable mineralogies spanning a broad range of the blueschist facies P-T conditions. o Bandon OR: BAN09, BAN15, LAB34 o Cycladic Islands: CY106, CY107 o Diablo Range CA: DR221, DR265 o New Caledonia: LAB555, LAB570, LAB572 o Catalina Schist CA: GB15-02A \u2022 Kinematically oriented thin sections prepared (foliation normal/lineation parallel) for EBSD analysis. Blueschist sample P-T estimates from the literature overlain on metamorphic facies diagram with slab-top paths of van Keken et al. (2018). VI. Future Work \u2022 The remaining mafic blueschist samples targeted for this study will be mapped, analyzed, and integrated into the framework of this compilation study. \u2022 Synthetic receiver functions will be applied to subduction zone models using the results from this study to develop constraints applicable to imaging of blueschist-metamorphosed oceanic crust. \u2022 Deformation experiments on glaucophane samples at varying temperatures, strain rates, and initial grain sizes in combination with microstructural analysis of recovered samples will be used to link observations of naturally deformed blueschists to an experimentally determined flow law. III. Methods \u2022 We can better understand subduction zone dynamics by using exhumed subduction exposures to constrain remote geophysical observations. \u2022 Seismic anisotropy can illuminate subduction zone structure and link deep processes to their expression as geological hazards at the surface. \u2022 Understanding the range of seismic anisotropy in mafic blueschists, a key constituent of subducting slabs, will improve imaging of the subduction zone interface. The seismic anisotropy of the blueschist samples (in AVp %) as a function of fabric strength of the [100], [010], and [001] pfJ-indices of glaucophane in the samples\u2014corresponding to the a-, b-, and c-axes respectively\u2014displays a general increase in magnitude of anisotropy with glaucophane fabric strength. The strongest correlation between pfJ-index and AVp % occurs with the [100] direction. Misorientation to mean orientation maps of glaucophane in samples CY107 (top) and GB15-02A (bottom), representative of samples near the deepest and shallowest extents of warm slab-top paths under blueschist facies conditions. Deformation microstructures show evidence of intragranular misorientation gradients and subgrain boundary formation that suggest deformation may be facilitated by dislocation creep. The seismic anisotropy (in AVp %) of the blueschist samples displays a general increase in magnitude with increasing volumes of glaucophane in the sample. The seismic wave velocity orientations (AVp patterns) can be divided into 2 main types: 1) Fast-velocity girdle in the foliation plane with slow-velocities normal to the foliation that corresponds to a glaucophane CPO with point-maxima in the a-, b-, and c-axes, and 2) Fast-velocity direction parallel to the sample lineation with a slow-velocity girdle normal to the lineation direction corresponding to a glaucophane CPO with the c-axis oriented along the lineation and a girdle formed by the a- and b-axes. VII. Abstract and References Blueschists show strong seismic anisotropy, scaling with glaucophane volume and fabric strength. This is likely a useful tool for imaging subducting slabs with receiver functions. V. Key Takeaways \u2022 The seismic anisotropy of mafic blueschists is largely controlled by the modal percentage of the amphibol", "label": "poster"}
{"text": "Estimation of Under-5 Mortality by Wealth Quintile Fengqing Chao1, Danzhen You2, Jon Pedersen3, Lucia Hug2, Leontine Alkema4 1(Email: ephchf@nus.edu.sg), Saw Swee Hock School of Public Health, National University of Singapore. 2Division of Data, Research and Policy, UNICEF. 3Fafo Institute of Applied International Studies, Fafo. 4Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst. Poster 11833, Poster Session P3 \u2013 Data, Methods, and Professionalization, Population Association of America, Apr 27th 2017, Chicago Introduction Objective \u25b6Estimate the levels and trends of under-5 mortality rate (U5MR; probability of dying before age 5) by wealth quintile across countries from 1990 to 2015; \u25b6Estimate the relation between ratios of quintile-speci\ufb01c U5MR and the national-level U5MR (all quintiles combined); \u25b6Implement a reproducible statistical model; Wealth Quintiles \u25b6Refer to 5 equal-size birth groups with di\ufb00erent levels of socioeconomic status according to the wealth index assigned to each household; \u25b61st wealth quintile = the poorest group; 5th wealth quintile = the richest group. Wealth Index \u25b6Computed based on selected questions asked in the Demographic Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS); \u25b6Indicator variables: any item that will re\ufb02ect economic status: \u25b6Type of \ufb02ooring (dirt/cement/parquet)? Type of toilet (bush/\ufb02ush)? Has electricity? Number of members per sleeping room? etc. \u25b6Use principal component analysis (PCA) to assign the indicator weights, and get the weighted sum as the wealth index. Data Data Types # surveys DHS direct 208 MICS direct 17 MICS indirect 66 total 291 Table: Database for modeling. \u2018Direct\u2019: full birth history data. \u2018Indirect\u2019: summary birth history data. \u25b695 countries with DHS and/or MICS survey data; \u25b6Each survey has 1 data point for each quintile; \u25b6Range of reference year: 1987 \u2013 2011. Results 1985 1995 2005 2015 0.4 0.6 0.8 1.0 1.2 1.4 1.6 Wealth Quintile Group 1 Quintile\u2212specific / Total U5MR Country estimate Global expected 1985 1995 2005 2015 0.4 0.6 0.8 1.0 1.2 1.4 1.6 Wealth Quintile Group 2 1985 1995 2005 2015 0.4 0.6 0.8 1.0 1.2 1.4 1.6 Wealth Quintile Group 3 1985 1995 2005 2015 0.4 0.6 0.8 1.0 1.2 1.4 1.6 Wealth Quintile Group 4 1985 1995 2005 2015 0.4 0.6 0.8 1.0 1.2 1.4 1.6 Wealth Quintile Group 5 1985 1995 2005 2015 50 100 150 200 U5MR (deaths per 1000 livebirth) quintile\u2212specific total 1985 1995 2005 2015 50 100 150 200 1985 1995 2005 2015 50 100 150 200 1985 1995 2005 2015 50 100 150 200 1985 1995 2005 2015 50 100 150 200 India 1985 1995 2005 2015 0.7 0.8 0.9 1.0 1.1 1.2 1.3 Wealth Quintile Group 1 Quintile\u2212specific / Total U5MR Country estimate Global expected 1985 1995 2005 2015 0.7 0.8 0.9 1.0 1.1 1.2 1.3 Wealth Quintile Group 2 1985 1995 2005 2015 0.7 0.8 0.9 1.0 1.1 1.2 1.3 Wealth Quintile Group 3 1985 1995 2005 2015 0.7 0.8 0.9 1.0 1.1 1.2 1.3 Wealth Quintile Group 4 1985 1995 2005 2015 0.7 0.8 0.9 1.0 1.1 1.2 1.3 Wealth Quintile Group 5 1985 1995 2005 2015 100 150 200 250 300 U5MR (deaths per 1000 livebirth) quintile\u2212specific total 1985 1995 2005 2015 100 150 200 250 300 1985 1995 2005 2015 100 150 200 250 300 1985 1995 2005 2015 100 150 200 250 300 1985 1995 2005 2015 100 150 200 250 300 Chad Model estimates and 90% CI for India and Chad. Row 1: ratio of wealth quintile-speci\ufb01c to national-level U5MR. Row 2: wealth quintile-speci\ufb01c and national-level U5MR. 0 20 40 60 80 1.0 1.5 2.0 2.5 3.0 Difference between U5MRQ1 and U5MRQ5 Ratio of U5MRQ1 to U5MRQ5 CMR CIV GHA HTI MWI MDA NAM NIC PRY ALB AZE BLZ BEN ERI GIN PSE TJK THA AFG ARM BLR BDI COL COG GAB GEO GUY MKD MDV MRT SRB SWZ SYR TUN UKR UZB ZMB AGO BGD BTN BOL BFA KHM CAF TCD COM COD DOM EGY GNQ ETH GMB GTM GNB HND IND IDN IRQ KEN KGZ LAO LSO LBR MDG MLI MNG MAR MOZ NPL NER NGA PAK PHL RWA STP SEN SLE SOM ZAF SSD SDN SUR TZA TLS TGO UGA VUT VNM YEM ZWE BRA JOR KAZ PER TUR G G G G G G South Asia CEE/CIS Sub\u2212Saharan Africa Latin America and the Caribbean East Asia an", "label": "poster"}
{"text": "Pile-up rejection for AMoRE-II Yoomin Oh References: [1] K.S. Park et al, DOI:10.3389/fphy.2024.1323991. [2] G.B. Kim et al, DOI:10.1016/j.astropartphys.2017.02.009. [3] S.C. Kim et al, DOI:10.1088/1748-0221/17/07/P07034. [4] C. Augier et al, DOI:10.1103/PhysRevLett.131.162501. [5] T. Chen and C. Guestrin, DOI:10.1145/2939672.2939785. [6] V. Alenkov et al, DOI:10.1140/epjc/s10052-022-11104-3. AMoRE: 0\u03bdDBD search \u2022 Mo-100 enriched scintillation crystal. \u2022 Cryogenic detector technique (MMC). \u2022 AMoRE-II using 157 kg of Li2MoO4. \u2022 Being prepared at 1000 m underground in Yemilab [1]. \u2022 5+ years running: mass\u00b7time exposure > 500 kg\u00b7year. \u2022 Energy resolution ~ 10 keV FWHM at Q\u03b2\u03b2=3034 keV. \u2022 Background level \u226a 2\u00d710-4 count/keV/kg/year (ckky). \u2022 Half-life sensitivity ~ 4\u00d71026 years at 90% CL. Pile-up background \u2022 Preference for a larger-size crystal detector to reduce the number of detector channels (~\u20ac$\u20a9). \u2022 Random coincidence of two signals in a detector crystal volume. \u2022 Expecting the largest contribution from two 2\u03bdDBD signals. \u2022 Rate scales with the crystal size (internal~volume, external~area) and coincidence t window. \u2022 For Li2MoO4 with \u03a6/H=6 cm and a 500 \u00b5s coincidence time window (\u0394t): pile-up background rate at ROI ~ 2.2\u00d710-4 ckky [4]. \u2022 Rejection at the analysis level is required with \u03b5rejection\u227390%. 2\u03bd\u03b2\u03b2 random coincidence Each total Pile-up simulation and analysis \u2022 Signal templates of Li2MoO4 detectors from R&D data: 1. Fast signal: rise-time ~ 1.9 ms, 10-90%, (Diffused surface / 20 mK / MMC thermal link to Cu-frame \u274d) 2. Slow signal: rise-time ~ 5.8 ms, 10-90%, (Diffused surface / 10 mK / MMC thermal link to Cu-frame \u2715) \u2022 Noise (baseline): randomly sampled from real data. \u2022 Analysis utilizing a machine learning method: gradient boosting [5]. Selected parameters for discrimination and training/evaluation data samples Pileup Single Single Pileup Pileup Single Pileup Pileup Single Single Pileup Single Pileup Pileup Single Pileup Pileup Single Pileup Pileup Single Pileup Pileup Single Pileup Pileup Single Pileup samples Butterworth bandpass filters with different cutoff frequencies Raw heat Raw light Raw heat Raw light Validation using real data: Bi-Po \u03b2-\u03b1 decay \u2022 A CaMoO4 crystal detector with a high U/Th contamination in AMoRE-I [6]. 214Bi \u03b2\u2212decay \u2212\u2212\u2212\u2212\u2212\u2212\u2212\u2212! Q=3.27 MeV 214Po (T1/2 = 164 \u03bcs) \u03b1\u2212decay \u2212\u2212\u2212\u2212\u2212\u2212\u2212\u2212! Q=7.83 MeV \u00b7\u00b7\u00b7 212Bi \u03b2\u2212decay \u2212\u2212\u2212\u2212\u2212\u2212\u2212\u2212! Q=1.88 MeV 212Po (T1/2 = 299 ns) \u03b1\u2212decay \u2212\u2212\u2212\u2212\u2212\u2212\u2212\u2212! Q=8.95 MeV \u00b7\u00b7\u00b7 Selection efficiency ~97% for single \u03b1 events Some can be discriminated. Rejection efficiency~60% Expecting no rejection at all! Signal and noise characteristics affects pile-up rate \u2022 A faster signal and higher signal/noise preferred for less pile-up rate [2]. \u2022 Signal parameters such as size and speed (rise-/decay-time) can be tuned with: 1. temperature, 2. crystal surface condition, 3. thermal link between sensor (MMC) and Cu frame [3]. \u2022 Baseline r.m.s. can be controlled to be as small as a few keV level. Result and Discussion \u2022 Rejection efficiency for the pile-up of 2\u03bdDBD signals at ROI in 500 \u00b5s: \u2022 Better than 90% with faster signals on lower noise baselines. \u2022 Close to 80% with slower signals on higher noise baselines. \u2022 Selection efficiency for the single signal event > 95%. \u2022 Pile-up rate by 2\u03bdDBD at ROI can be suppressed down to (2\u20134)\u00d710-5 ckky. \u2022 Studying the possibility for further improvements, not only for pile-up discrimination but also for more general event type classification. yoomin@ibs.re.kr Fast signal, Lower noise case", "label": "poster"}
{"text": "VIDEO ABSTRACTS: DO THE METRICS STACK UP? Tom Rees1, Sandra L\u00ea2, Leigh Prevost1, and Sheelah Smith1 1PAREXEL International, Worthing, UK; 2Dove Medical Press, Macclesfield, UK Objective: Video abstracts offer a means to present results that complement the full paper. We aimed to compare video abstract views with other publication metrics in order to understand better the role they play in disseminating research findings. Research design and methods: Metrics were obtained from YouTube for all video abstracts published by the open-access publisher, Dove Medical Press. All articles with video abstracts published in four journals in different therapy areas over the period February 27, 2014, to March 19, 2015, were analyzed (average time since publication: 212 days), and compared with metrics for matched articles without video abstracts. Results: A total of 31 articles with video abstracts were identified. Average number of views per video was 364; most views came from United States, India, and United Kingdom. Males were 66% of viewers and 36% were aged 25\u201334 years. In our sample, video abstracts did not increase with time. Video views were weakly correlated with text abstract views (r-squared = 0.22) and with full paper views (r2 = 0.23) with around 1.5 video views per full paper view. Full views of papers with a video abstract were similar to those of papers without. Conclusions: Video abstracts are of interest to many authors and readers and complement full views. This is in line with authors\u2019 and publication professionals\u2019 views that publishing a video abstract increases the reach of research results and may increase downloads. UPDATED ABSTRACT \u2022 Video abstracts offer a novel means to present study results that can both complement and enrich the full published article. \u2022 Presenting results through a different medium could address the learning style preferences of a wider group. \u2022 In an accompanying poster, we present survey results that indicate high levels of interest from authors in video abstracts although concerns over impact and value were raised. INTRODUCTION \u2022 Video abstracts appear to be more popular with younger audiences. \u2022 The low correlation between video abstract, conventional abstract and full paper views suggests that they are reaching different audiences; however, video abstracts do not appear to replace or encourage full paper views. SUMMARY AND CONCLUSIONS \u2022 In this exploratory analysis, we aimed to compare video abstract views with other publication metrics in order to understand better the role that video abstracts play in disseminating research findings. OBJECTIVE RESULTS \u2022 Across the Dove Medical Press portfolio, the mean number of views per video abstract was 364. Scan QR code to download this poster Scan QR code to download any of PAREXEL\u2019s and Dove Medical Press\u2019 posters presented at ISMPP Acknowledgments The authors would like to acknowledge and thank PAREXEL Editorial and Creative Services for their support. 11th Annual Meeting of ISMPP; April 27\u201329, 2015, Arlington, VA, USA. \u2022 Aggregate viewing statistics for all video abstracts published by Dove Medical Press, an open-access publisher, were obtained from YouTube. \u2022 Four journals published by Dove Medical Press across diverse medical fields were identified: Clinical Ophthalmology, Therapeutics and Clinical Risk Management, International Journal of Chronic Obstructive Pulmonary Disease, and Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. \u2022 Metrics for all papers with video abstracts published over a 12-month period (February 27, 2014, to March 19, 2015) were obtained (including original research articles, reviews, case series, and case reports). \u0082\u0082 Views on PubMed Commons were excluded from this analysis. \u2022 For the control group we identified, for each video abstract, the article of the same type closest in publication date, but without a video abstract. \u2022 Relationships were explored using linear regression, two sample T-tests and, for ", "label": "poster"}
{"text": "What determines the inner sizes of protoplanetary disks? I. Mendigut\u00eda1,*, P. Marcos-Arenal1,2, E. Koumpia3, R.D. Oudmaijer4, M. Vioque5,6, J. Guzm\u00e1n-D\u00edaz1, C. Wichittanakom7, W.J. de Wit3, B. Montesinos1, J.D. Ilee4 1 Centro de Astrobiolog\u00eda (CAB), CSIC-INTA, Madrid, Spain 2 European Space Agency, ESA-ESAC, Madrid, Spain 3 European Southern Observatory, Santiago, Chile 4 University of Leeds, UK 5Joint ALMA Observatory, Santiago, Chile 6National Radio Astronomy Observatory, Charlottesville, USA 7Thammasat University, Pathum Thani, Thailand * imendigutia@cab.inta-csic.es Background Planets form in gas and dust disks that surround young stars. Dust particles do not survive temperatures above 1000-2000 K, for which protoplanetary disks are cleared of dust close to the central stars. The size of such inner dust holes should be larger for more luminous (hotter) sources, ranging between ~ 0.01 and 20 au in optically-visible young stars. This range is critical for our understanding of planet formation, as it corresponds to the region where most exoplanets\u2019 orbits lie1. In turn, those inner disk sizes translate to angular scales of milli-arcsecs even for the closest sources, and can be resolved mainly for intermediate-mass \u201cHerbig Ae/Be\u201d stars only by using near-infrared interferometry. Although previous interferometric studies have shown that there is a correlation linking the stellar luminosity of Herbig Ae/Be stars and the size of their inner dust disks, this \u201csize-luminosity correlation\u201d may change for early type Herbig Bes and shows considerable scatter2,3. The main physical scenarios proposed to explain the observed size-luminosity distribution are related to the presence/absence of innermost gas, different disk-to-star accretion mechanisms, or different dust disk properties as inferred from spectral energy distributions (SEDs)4,5,6. However, no general observational confirmation has been provided to date. Our goal is to identify the physical mechanism that drives the observed distribution in the size-luminosity correlation. References (see the associated paper Marcos-Arenal et al. 2021, A&A, 652, A68) Fig. 1. Example: the young star V590 Mon. (Left) GRAVITY/VLTI interferometric observables -flux (red), squared visibility (blue) and differential phase (green)- vs wavelength around the Br\u0263 emission line for two different VLT baselines. (Right) Continuum squared visibilities vs spatial frequency (solid dots with errorbars). The best fit is indicated with a solid line and corresponds to a Gaussian disk on top of the central star, leading to an inner dust disk radius ~ 2 au. Alternative fits corresponding to ring and uniform disk models are plotted with dashed and dot-dashed lines. XV Reuni\u00f3n Cient\u00edfica Sociedad Espa\u00f1ola de Astronom\u00eda. Tenerife. September 2022 1: http://exoplanet.eu/ 2: Monnier & Millan-Gabet. 2002, ApJ, 579, 694 Fig. 2. (Left) Size-luminosity relation where each panel emphasizes a different aspect. Top left: Herbig Ae and Herbig Be stars; the five with our new GRAVITY data are highlighted in red. Top right: the sources with strong (blue) and weak (red) accretion rates. Bottom left: the sources with spectro-interferometric measurements indicating the presence of atomic gas inside the inner dust disk (blue) and the ones without such evidence (red). Bottom right: Group I and Group II sources based on the SED shape. For all panels, triangles indicate upper and lower limits and the solid and dashed lines indicate the expected boundaries of the inner dust disk radius based on the two main accretion scenarios and innermost gas densities. (Right) Size-luminosity relation where the stars have been color-coded to indicate different distance ranges, the rest of the symbols and lines as in the left panel. disk Results 1) We have updated the size-luminosity diagram, almost doubling the number of optically visible young stars considered in previous works. 2) We find no general trend linking the presence/absence of innermost gas,", "label": "poster"}
{"text": "Predictive Modeling of Polymer-Derived Ceramics: Discovering Methods for the Design and Fabrication of Complex Disordered Solids Paul Rulis1 , Nathan Oyler2 , Michelle Paquette1, Ridwan Sakidja3, Jinwoo Hwang4 1. Department of Physics and Astronomy, University of Missouri - Kansas City, Kansas City MO 64110 2. Department of Chemistry, University of Missouri - Kansas City, Kansas City MO 64110 3. Department of Physics, Astronomy and Materials Science, Missouri State University, Springfield MO 65897 4. Department of Materials Science and Engineering, The Ohio State University, Columbus OH 43212 Program Objective \u2022 Toward the long-term goal of creating an integrated program for the design of complex disordered solids, this new project aims to develop a general, simulation- driven methodology for accurately recreating the atomic structure of substructure- containing amorphous solids and mapping resultant structures and properties back to fabrication conditions, ultimately enabling a computational design capability. \u2022 The work involves developing an ab initio molecular dynamics (AIMD) and hybrid reverse Monte Carlo (HRMC) simulation that is augmented by ab initio total energy and a set of geometric constraints. We will use a collection of thin-film amorphous preceramic polymers (a-BC:H, a-SiBCN:H, and a-SiCO:H) as suitably complex and technologically relevant case studies. \u2022 We develop novel algorithms for linking growth conditions and characterization information to atomistic simulation, and for mapping fabrication conditions to desired properties. Our modeling goal is to first identify non-global potential energy minima for material sub-components that are produced under non-thermodynamic conditions and to then align the timescales of the simulation and growth processes so as to generate realistic structural models of complex disordered solids. \u2022 The project combines state of the art computational techniques (AIMD, HRMC), modern optimization algorithms (e.g. artificial neural networks (ANNs), particle swarm optimization (PSO)), specialized experimental characterization techniques, (solid-state nuclear magnetic resonance (NMR), 4-dimensional scanning transmission electron microscopy (4D-STEM)), and advanced thin-film fabrication technology (plasma enhanced chemical vapor deposition (PECVD)). \u2022 The unique utility of modern solid-state NMR techniques to obtain specific bonding and connectivity information and the sensitive medium-range order information available from 4D-STEM will be combined with neutron diffraction and more routine physical/electronic structure characterization methods to provide input and constraints for the simulations. The project includes (left) growth and characterization, (middle) iterative modeling, and (right) design training and validation. Single-frame red boxes represent experimental samples and data, while double-framed blue boxes represent computational products. The shaded region in the middle represents the application of particle swarm optimization. The general flow can be understood as: (1) growth of samples varied by composition and growth procedures; (2) experimental structural characterization; (3) iterative model simulation using characterization data; (4) ANN training to link simulation and growth parameters followed by predictive application of the ANN. Acknowledgement To meet the long-term goal of developing an integrated program for the fabrication of complex disordered solids that are designed to satisfy the performance requirements of advanced applications, we set the following plans for the first year of this project. 1. We will form connections between experimental characterization and simulated data to guide the construction of realistic models of preceramic polymers. Our working procedure for generating individual models is to prepare the composition for a large-scale classical MD simulation via smaller scale AIMD and to then use HRMC to progressively improve matching between the mod", "label": "poster"}
{"text": "Diagrams for PhD research By Scott Skipworth ORCID: https://orcid.org/0000-0003-2674-529X Disseminated Embodiment: My term for a repositioning of human embodiment for the 21st Century: no longer a distinct figure in relation to the built environment, but an expanding and contracting satellite system of the local and global built environment itself. Diagram by Scott Skipworth ORCID: https://orcid.org/0000-0003-2674-529X Embodied student physically at site visit while meeting with studios at remotely located campuses through mobile technology: student is disseminated \u2013 in \u201cplace\u201d across locations: Where to put one X to represent student figure in a place? (can\u2019t) Diagram by Scott Skipworth ORCID: https://orcid.org/0000-0003-2674-529X Embodied client/user physically at home interacting with remote urban site through personal (home) and building mounted (site) technology (body sharing?)\u2013 in \u201cplace\u201d across locations: Where to put one X to represent the user figure in a place? (can\u2019t) Existing framework/model of human embodiment as figure in a built environment \u201cplace\u201d no longer works Existing framework/model of human embodiment as figure in a built environment \u201cplace\u201d no longer works", "label": "poster"}
{"text": "1 Unidad de Genotipado y Diagn\u00f3stico Gen\u00e9tico (UGDG), INCLIVA, Valencia (Spain) 2 Unidad de Bioinform\u00e1tica, INCLIVA, Valencia (Spain) 3 Hospital Universitari de Tarragona Joan XXIII / IISPV / Universitat Rovira i Virgili / CIBERDEM (Spain) Daniel P\u00e9rez-Gil1,2, Ver\u00f3nica Lend\u00ednez-Tortajada1, Alba Sanchis-Juan1,2, Pilar Rentero-Garrido1, Ana Meg\u00eda3, Joan Vendrell3, Felipe Javier Chaves-Mart\u00ednez1, Pablo Mar\u00edn-Garc\u00eda1,2 DPMAS: pipeline for 450K top table replication with MiSeq amplicons ABSTRACT DNA methylation is one of the most important epigenetic modifications in gene expression regulation and it plays a crucial role in multiple biological processes. Therefore, DNA methylation profiling is important to reveal regions of the genome that are altered during development or that are perturbed by disease. Methylation signals at CpG sites can be assessed using bisulfite conversion method and massive sequencing technologies. Here we present the implementation of a bioinformatics pipeline for replication with MiSeq sequencing amplicons of the top hits obtained from Infinium 450K differential methylation experiments. CONCLUSIONS We have implemented a bioinformatics pipeline for replication of the top hits obtained from Infinium 450K experiments using MiSeq sequencing amplicons. For this purpose we have used well-established software for genome analysis as well as applications developed in our lab, all of them open source. The proposed workflow has proved to be useful for methylation level assessment while maintaining a good data quality control. Source code will be available at: https://github.com/pamag/DPMAS PIPELINE REPORT 450K results The assessment of methylation level at CpG sites from raw genetic sequences involves quality control and several processing steps. The main building blocks of the pipeline include SNP selection from 450K experiments, sequencing of the regions containing those SNPs with directional primers, mapping of the reads to the reference amplicon sequences and variant calling at cytosines in CpG sites. Finally, a dashboard report is produced as an analysis summary. Other SNP selection Directional amplification primers design MiSeq sequencing Adaptor removal and quality trimming Mapping Min length filter Calling C and T counts REPORT Beta values plot FASTQ BAM VCF Figure 2. Coverage plot. Depth per base distribution is plotted for each sample (black lines) in every experimental group. In this example a threshold of 100x is established as a minimum value to report reliable results (red line). Figure 3. Methylation plots. Beta values plot (A). Methylation percentages of CpG sites along the amplicon are plotted for each sample in every experimental group. The 450K selected SNPs are highlighted as a red line. In this example only those samples with coverage >=100 at the CpG site are plotted. A reliability value is assigned to each point depending on the error assumed when the methylation level is assigned (B). Figure 1. Localization plot. The region where the selected 450K SNPs are located is plotted. Chromosome and gene transcripts are displayed and the CpG of interest is shown as a red line. Table 1. Methylation level table. Mean, standard error and number of samples (mean\u00b1se(N)) are shown for each CpG site in every experimental group. The CpG site of interest is highlighted in red. Position c1 c2 c3 c4 64 77.71\u00b10.63(46) 79.03\u00b10.49(85) 78.69\u00b10.61(60) 78.61\u00b11.02(62) 105 89.76\u00b10.37(46) 89.3\u00b10.42(85) 90.38\u00b10.45(60) 89.82\u00b10.6(61) 108 94.75\u00b10.21(46) 95.01\u00b10.24(85) 94.62\u00b10.24(60) 94.61\u00b10.42(62) 119 54.15\u00b14.57(46) 52.69\u00b13.43(85) 55.51\u00b14.14(60) 56.16\u00b13.84(63) 127 95.71\u00b10.18(46) 95.89\u00b10.19(85) 95.82\u00b10.28(60) 96.2\u00b10.38(62) 187 92.49\u00b10.46(46) 92.57\u00b10.31(85) 92.91\u00b10.27(60) 92.88\u00b10.56(62) 218 96.03\u00b10.21(46) 96.21\u00b10.27(85) 96.3\u00b10.23(60) 96.46\u00b10.33(62) A) B) c1 c2 c3 c4 c1 c2 c3 c4 c1 c2 c3 c4 c1 c2 c3 c4", "label": "poster"}
{"text": "About the agreement To achieve the large-scale transformation towards open access, the project partners devised a \u201cPublish and Read\u201d (PAR) model with two components: The Projekt DEAL-Wiley agreement Significantly increased open access output from German research institutions. Enabled researchers from German institutions to easily publish their work open access, independently from available funding in their research areas, and retain copyright for their work. Expanded access to research findings for German institutions. Expand equal access to high-quality scholarly journals to all researchers in Germany. Analysis Wiley and the project partners are constantly monitoring the publishing output. Now that the agreement has been in effect for over two years,what are the actual changes in publishing and reading behaviour Wiley was able to observe? After the second year of this agreement, it is possible to draw the reasonable conclusions about impact and achievements: The two Key goals of the Projekt DEAL-Wiley agreement: Transitioning to an open future Wiley\u2019s commitment to open access Empower all (corresponding) authors with the means to publish their articles openly. Gold Open Access increase in the number of Gold journal published articles from 2018 to 2020. increase the number of accepted and approved articles in 2020, compared to 2019. Hybrid Open Access increase in the number of articles published open access. of authors choose to publish OA in our journals of authors choose a CCBY license Open Access Publishing The Projekt DEAL-Wiley agreement has already made notable advancement towards a higher ratio of open access publications. articles published in Wiley\u2019s hybrid portfolio between July 2019 and December 2020. articles published in Wiley\u2019s Gold Open Access journals in 2019 and 2020. Outcomes: Reading accesses to full text HTML and PDF (2020). increase in usage since before the agreement. Participation and reach institutions where Readers have reading rights (2020). Publish component: \u2022 Authors publishing in Wiley\u2019s 1,400+ hybrid journals may publish OA at no direct cost to them; Projekt DEAL pays a PAR fee of 2.750\u20ac to Wiley per such article \u2022 Authors can publish in 230+ fully gold open access journals at no direct cost*, and institutions get a 20% discount on the Article Publication Charge (APC). Read component: \u2022 Participating institutions gain free read access to more than 1,600 Wiley journals (dating back to 1997) Outcomes: Introduction In January 2019, Projekt DEAL, a consortium representing German research institutes and academic libraries, signed a large-scale open access agreement with Wiley, publisher of over 1,600 peer-reviewed journals from all areas of research. Its goal was to accelerate the nation-wide transition from a predominantly subscription- based publishing model to one based on open access. It is intended to significantly raise the number of open access articles being published out of German research institutions while securing, and even expanding institutions\u2019 read access to Wiley\u2019s journal output at the same time. >1000% 92% 15,716,977 49% 495 58% 92% + 14,500 + 1,500 Participation and reach institutions where eligible authors have open access publishing rights. (2020) 943 Conclusions + 50% *Some institutional funding policies may differ for gold OA APCs. Authors should check with their library for any exceptions. Authors: Melanie Lehnert-Bechle (Wiley-VCH), Torben Quasdorf (Wiley-VCH), Eva-Maria Scheer (Wiley-VCH) This work is licensed under a Creative Commons Attribution 4.0 International License.", "label": "poster"}
{"text": "\u2022 has attracted over 900 registered users world-wide, up from 400 users in 2013 SI2-SSE: Modules for Experiments in Stellar Astrophysics (MESA) The goal of this project is to support the MESA software infrastructure by providing sustained innovation in the astrophysics community. MESA solves the 1D fully coupled structure and composition equations governing stellar evolution with implicit \ufb01nite volume scheme. State-of-the-art modules provide adaptive mesh re\ufb01nement, sophisticated timestep controls, non-adiabatic oscillation capabilities, equation of state, opacity, nuclear reaction rates, element diffusion, boundary conditions, and changes to the mass of the star. MESA has signi\ufb01cant penetration in the astrophysics community and is well on its way to becoming the world standard for evolving stars, providing a crucial resource to the astrophysical community at just the right time. The third year of our SI2-SSE award has been key to sustaining MESA as an essential piece of software infrastructure while building new scienti\ufb01c and educational networks. \u2022 software instrument papers MESA I (2011), MESA II (2013), and MESA III (2015) have collectively been cited over 1000 times. Each paper ranks in the Top 25 most cited astronomy and astrophysics paper published in that year. Frank Timmes (PI), Rich Townsend (Co-PI), Lars Bildsten (Co-PI), Bill Paxton (MESA\u2019s First Author). MESA: ~300 Registered USA Users Sept. 2016 South Pacific Ocean South Atlantic Ocean North Atlantic Ocean North Pacific Ocean Indian Ocean MESA: ~915 Total Registered Users Sept. 2016 0 15 30 45 2012 2013 2014 2015 2016 Grads Postdocs Undergrads Faculty Amateurs 28% female 80% USA 66% USA 39% female 64% USA 33% female 68% USA 47% female 48% USA 32% female Citations 0 100 200 300 2011 2012 2013 2014 2015 Sept. 2016 MESA I 2011 MESA II 2013 MESA III 2015 Total Citations: 947 as of 01Sep2016 \u2022 had one paper, MESA II, that was one of 15 papers selected by the American Astronomical Society for \u201chigh-impact research\u201d published between 2012 and 2015. MESA was publicly launched in 2011 and received an SI2-SSE award in 2013. The MESA project \u2022 has witnessed over 10,000 downloads of the source code \u2022 has distributed over 12,000 archived and searchable posts on community discussions \u2022 provides a Software Development Kit to build MESA across a variety of platforms \u2022 delivers an annual Summer School program that now has over 170 graduates which offers a week of extensive hands-on labs on how use MESA in their own research \u2022 hosts a web-portal for the community to share analysis tools and build provenance \u2022 offers a prototype of a cloud resource for education, MESA-Web, that has served up over 1500 models for education to 40 institutions in the USA unique users in its \ufb01rst year of operation.", "label": "poster"}
{"text": "Bringing Interoperable Annotation to All Scholarly Works Annotating All Knowledge Coalition and Working Group A coalition of some of the world\u2019s key scholarly publishers, platforms, libraries, and technology organizations are coming together to create an open, interoperable annotation layer. Web annotation is here! Our goal is to make it pervasive across scholarship, open and interoperable. For decades web pioneers have imagined a native and universal collaborative capability over the Web. Many projects have experimented with it, yet in 2015 we\u2019re still stuck with the same patchwork of proprietary commenting systems, only available in some places. In the last few years a growing community has been working to change that. Our goal is to standardize \u201cannotation\u201d as a unit of conversation built into the very fabric of the Web. In late 2014 the World Wide Web Consortium (W3C), the standards body for the Web, established a formal Working Group to support this standards e\ufb00ort. Much progress has been made, and many implementations are now mature enough to be deployed. What\u2019s possible with web-based annotation? Make persistent annotations in texts by highlighting passages, adding notes, and tagging with keywords. Coalition Founding Members American Geophysical Union \u25cf Amherst University Library \u25cf Annual Reviews \u25cf arXiv \u25cf Atypon \u25cf Authorea \u25cf Biodiversity Heritage Library \u25cf biorxiv \u25cf Brandeis University Library \u25cf Cambridge University Press \u25cf CELI \u25cf Carnegie Mellon University \u25cf Centre for Agriculture and Biosciences \u25cf International Center for Open Science \u25cf Collaborative Knowledge Foundation \u25cf ContentMine \u25cf Crossref \u25cf Duke University Press \u25cf eLife \u25cf Elsevier \u25cf Europe PubMed Central \u25cf Europeana \u25cf F1000 - Faculty of 1000 \u25cf Factminers \u25cf Gigascience \u25cf Harvard- Smithsonian Center for Astrophysics \u25cf HathiTrust \u25cf Highwire \u25cf Hypothes.is \u25cf IDPF \u25cf iPython / Project Jupyter \u25cf JHU MUSE \u25cf Journal of Neuroscience Research \u25cf JSTOR \u25cf Knowledge Unlatched \u25cf Michigan Publishing \u25cf MIT Press \u25cf NASA Astrophysics Data System \u25cf NYU Press and NYU Libraries \u25cf O\u2019Reilly Books (aka Safari Books Online) \u25cf PKP / Open Journal Systems \u25cf Publishing Technology plc \u25cf ORCID \u25cf Oxford University Press \u25cf PaperHive \u25cf Pensoft \u25cf PLOS \u25cf Pressbooks \u25cf RedLink \u25cf Romanian Center for Investigative Journalism \u25cf Semantico \u25cf SSRN \u25cf Stanford University Libraries \u25cf Ubiquity Press \u25cf University of California Davis Library \u25cf University of California Press \u25cf University of Illinois Libraries \u25cf University of Southern California - Scalar \u25cf Unizin \u25cf W3C \u25cf Wellcome Library \u25cf Wiley \u25cf Wolfram \u25cf World Archives of Sciences \u25cf World Digital Mathematics Library \u2013 \u2013 \u2013 \u2013 \u2013 \u2013 Goal To deploy an interoperable annotation layer over all scholarly and scienti\ufb01c works within three years. \u2013 Members agree to Share the vision for how this can bene\ufb01t scholarship Explore how to incorporate web annotation Collaborate openly with others Be open about their participation \u2013 \u2013 \u2013 \u2013 Annotating All Knowledge Coalition AAK Working Group was established at FORCE11 to support the work of the AAK Coalition. Support the communication and dissemination needs of the coalition Provide a forum for AAK Coalition discussions Coordinate technical working group Organize Face to Face meeting at FORCE2016 \u2013 \u2013 \u2013 Timeline \u2013 \u2013 \u2013 \u2013 Face to Face Kick O\ufb00 Meeting >55 attendees can network Establish a working de\ufb01nition of interoperability De\ufb01ne the most compelling use cases/user stories to drive technology development Organize a technical speci\ufb01cations working group Discuss branding \u2013 \u2013 \u2013 \u2013 \u2013 AAK Working Group The coalition is open to any scholarly publisher, platform, library or technology organization that shares our vision and objectives and wants to participate. Contact us at: coalition@hypothes.is for more information. Join the working group at FORCE11 Contribute your use cases Contribute your talent Build open annotation into your platform \u2013 \u2013 \u2013 \u2013 Participate Upcoming events I Annotate Berlin, May 19-20, 2016 \u2013 Join us! hypothes.is/annotating-a", "label": "poster"}
{"text": "d matthias de Fr\u00e9 Jeroen van der Hooft Tim Wauters Filip De Turck how to Realize an immersive Jedi Council meeting a Capturing Story of holograms and Their hyperdrive delivery", "label": "poster"}
{"text": "Sample Ms Mr Bc Bcr Mr/Ms Bcr/Bc B2861 1.21 0.267 11.63 21.02 0.221 1.807 B4591 0.34 0.14 29.25 41.7 0.412 1.426 B5981 1.3 0.2 6.79 12.94 0.154 1.906 B7151 0.95 0.113 3.29 6.24 0.119 1.897 Image credit: IODP, Blastcube from wiki AF Thermal Can we use field dependence of susceptibility to identify the magnetic mineralogy of submarine basalts? Hong Yang (hyang777@Stanford.edu), Sonia M. Tikoo | Dept of Geophysics/Dept of Earth & Planetary sciences, Stanford University Dario Bilardello, Peat Solheid | Institute for Rock Magnetism, University of Minnesota IODP Expedition 391 scientists 30-second Summary Background & Motivation Sample Info \u03c7Hd = (\u03c7300 A/m -\u03c730 A/m)/\u03c730 A/m -100 x10 -3 -50 0 50 100 0.16 0.12 0.08 0.04 0.00 Bc (T) 600 400 200 0 -200 -400 -600 Am 2/T 2 Bu (T) -100 x10 -3 -50 0 50 100 0.12 0.08 0.04 0.00 Bc (T) 400 300 200 100 0 Am 2/T 2 Bu (T) -100 x10 -3 -50 0 50 100 0.12 0.08 0.04 0.00 Bc (T) 2500 2000 1500 1000 500 0 -500 Am 2/T 2 Bu (T) \ud835\udf12= 1% \ud835\udf12= 5% \ud835\udf12= 51% \ud835\udf12= 14% -100 x10 -3 -50 0 50 100 0.16 0.12 0.08 0.04 0.00 Bc (T) 600 400 200 0 -200 Am 2/T 2 Bu (T) T (\u2103) k (10-6 SI) k (10-6 SI) T (\u2103) k (10-6 SI) T (\u2103) k (10-6 SI) T (\u2103) Preliminary Conclusions Acknowledgement References heating cooling heating cooling heating cooling heating cooling To help guide the choice of demagnetization method of submarine basalts in shipboard/lab measurements, we test if room temperature field dependence can be used to infer the magnetic mineralogy of submarine basalts. We studied magnetic properties of basalts with different field dependences. We found the field dependence behavior is associated with Hopkinson peaks. High field-dependent basalts are characterized by reversible thermomagnetic curves and low Curie temperature and should be better treated with AF demagnetization. [1] Zhou W, Van der Voo R, Peacor D R, Zhang Y 2000 Earth Planet. Sci. Lett. 179 9 [2] \u00d6zdemir \u00d6 1987 Phys. Earth Planet. Inter. 46 184 [3] Furuta T 1993 Geophys. J. Int. 113 95 [4] Sager W, Hoernle K, Petronotis K 2020 [5] Jackson M, Moskowitz B, Rosenbaum J, Kissel C 1998 Earth Planet. Sci. Lett. 157 129 [6] Bilardello D 2023 IRM Q. 32-4 [7] Clark D A 2016 ASEG Extended Abstracts 2016 1 Field dependence data: Clark 2016 B2861 Deposit type: pillow lava Depth: 292.52m Location: (-32.32806, -0.643127) B5981 Deposit type: massive lava flow Depth: 391.32 m Location: (-32.32806, -0.643127) B4591 Deposit type: massive lava flow Depth: 174.09 m Location: (-25.202398, 7.4969) B7151 Deposit type: massive lava flow Depth: 181.92 m Location: (-25.202398, 7.4969) \u2022 Field-dependent behavior is associated with the Hopkinson peak, especially the rising part. \u2022 Real and Imaginary susceptibilities show different peak positions \u2022 The magnitude of room temperature field dependence depends on where the Hopkinson peak is, which is influenced by the Ti content of Titanomagnetite. \u2022 Samples with high field dependence is correlated with low Curie temperature and reversible k-T curve. They are better suited for AF demagnetization. \u2022 More to explore with field-frequency dependence? \u2022 We thank Institute for Rock Magnetism for awarding HY the visiting student fellowship to conduct this research. Additionally, we would like to extend our appreciation to Max Brown for his valuable assistance in arranging the visit. \u2022 The IRM is a US National Multi-user Facility supported through the Instrumentation and Facilities program of the National Science Foundation, Earth Sciences Division (NSF EAR -2153786), and by funding from the University of Minnesota.\u201d", "label": "poster"}
{"text": "MATERIALS AND METHODS Biomethane gasometer Raw biogas gasometer 100L Tank Settler Biogas (G) Settled Biomass Liquid Recirculation (L) Domestic wastewater or centrate Raw biogas composition: Biogas upgrading using algal-bacterial processes in wastewater treatment plants M. Rosario Rodero1,3, Raquel Lebrero1,3, Esteban Serrano2, Enrique Lara2, Zouhayr Arbib2, Ra\u00fal Mu\u00f1oz*1,3 1- Department of Chemical Engineering and Environmental Technology, University of Valladolid, Dr. Mergelina s/n., Valladolid 47011, Spain. 2- FCC Servicios Ciudadanos, Av. del Camino de Santiago, 40, edificio 3, 4\u00aa planta,28050 Madrid, Spain 3- Institute of Sustainable Processes, University of Valladolid, 47011, Valladolid, Spain * Author for correspondence: mutora@iq.uva.es INTRODUCTION RESULTS AND DISCUSSION CONCLUSIONS \uf0fcNegligible influence of the hydraulic retention time (HRT) in the HRAP and the biogas flowrate in the absorption column on the biogas upgrading performance. \uf0fcHigher CO2 and H2S removal efficiencies were obtained using centrate instead of domestic wastewater due to the higher alkalinity and pH of the influent. \uf0fcHigher L/G ratios entailed higher CO2 and H2S removals, but an increased stripping of N2 and O2 was observed, which negatively impacted CH4 concentration in the upgraded biogas. \uf0fcTo the best of our knowledge, this work demonstrated for the first time the capacity of algal-bacterial systems for the simultaneous biogas upgrading and wastewater treatment at semi-industrial scale. References: [1] Toledo-Cervantes A., Serejo M., Blanco S., P\u00e9rez R., Lebrero R., Mu\u00f1oz R., (2016). Photosynthetic biogas upgrading to bio-methane: Boosting nutrient recovery via biomass productivity control. Algal Res.17, 46-52. [2] Mar\u00edn D., Posadas E., Cano P., P\u00e9rez V., Blanco S., Lebrero R. and Mu\u00f1oz R. (2018). Seasonal variation of biogas upgrading coupled with digestate treatment in an outdoors pilot scale algal-bacterial photobioreactor. Bioresour. Technol. 263, 58-66 [3] Posadas, E., Serejo, M.L., Blanco, S., P\u00e9rez, R., Garc\u00eda-Encina, P.A., Mu\u00f1oz, R. (2015). Minimization of biomethane oxygen concentration during biogas upgrading in algal-bacterial photobioreactors. Algal Res. 12, 221\u2013229. Acknowledgments:The project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement No. 689242. Biogas, which mainly consists of CH4 (40-75%), CO2 (15-60%) and H2S (0.005-2%), constitutes a valuable renewable energy source able to reduce our current dependence on fossil fuels. In this context, H2S removal is mandatory due to its corrosive, malodorous and pernicious nature, while CO2 removal increases the specific calorific value and reduces biogas costs of compression and transportation [1]. Figure 2. Influence of the L/G ratio on biogas upgrading performance at biogas flowrate of 276 (black), 370 (white) and 459 (grey) L h-1 during stage I (a), stage II (b) and stage III (c). Effluent composition DWW, HRT= 3.5 days DWW, HRT = 8 days Centrate, HRT = 73 days COD (mg L-1) 99.4\u00b131.3 65.0\u00b121.7 123.8\u00b10 N-NH4 + (mg-N L-1) 3.1\u00b11.7 1.0\u00b11.1 0\u00b10 N-NO2 (mg-N L-1) 0.8\u00b10.5 0.4\u00b10.2 13.3\u00b111.7 N-NO3 (mg-N L-1) 2.0\u00b11.2 9.6\u00b10.5 38.1\u00b17.4 P-PO4 3- (mg L-1) 1.0\u00b10.5 1.3\u00b10.3 19.9\u00b15.4 Figure 3. Wastewater removal efficiencies in the high rate algal pond during stage I (white), II (black) and III (grey) Table 2. Effluent composition under steady state conditions Objetive: To assess the influence on biomethane composition of: \uf071L/G ratio: 1.2, 2.1 and 3.5 \uf071Biogas flow rate (G): 274, 370 and 459 L h-1 Parameter Stage I II III Type of wastewater DWW DWW Centrate HRT (d) 3.5 8 73 Average temperature (\u00b0C) 23.5\u00b12.5 12.4\u00b12.3 18.8\u00b13.0 Average pH in the cultivation broth 7.3\u00b10.2 7.1\u00b10.5 8.9\u00b10.3 Figure 1. Schematic diagram (left) and photograph (right) of the continuous biogas upgrading experimental plant at Aqualia\u2019s facility in Chiclana CH4 (%) 69.2\u00b14.9 CO2 (%) 32.7\u00b12.8 H2S (ppm) 1183\u00b11006 Biogas upgrading in algal\u2013bacterial photobioreactors re", "label": "poster"}
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\u0420\u0435\u0441\u043f\u0443\u0431\u043b\u0438\u043a\u0435 \u0422\u0430\u0442\u0430\u0440\u0441\u0442\u0430\u043d, \u043d\u043e \u0438 \u0432 \u0441\u043e\u0441\u0435\u0434\u043d\u0438\u0445 \u0440\u0435\u0433\u0438\u043e\u043d\u0430\u0445, \u043c\u043d\u043e\u0433\u0438\u043c\u0438 \u044d\u043d\u0442\u043e\u043c\u043e\u043b\u043e\u0433\u0430\u043c\u0438 (\u0410\u043b\u0435\u0439\u043d\u0438\u043a\u043e\u0432\u0430, 1964, 1979, \u0423\u0442\u0440\u043e\u0431\u0438\u043d\u0430, 1956, \u0416\u0435\u0440\u0435\u0431\u0446\u043e\u0432, 2000). \u0414.\u041d. \u0412\u0430\u0432\u0438\u043b\u043e\u0432 \u0418\u043d\u0441\u0442\u0438\u0442\u0443\u0442 \u043f\u0440\u043e\u0431\u043b\u0435\u043c \u044d\u043a\u043e\u043b\u043e\u0433\u0438\u0438 \u0438 \u043d\u0435\u0434\u0440\u043e\u043f\u043e\u043b\u044c\u0437\u043e\u0432\u0430\u043d\u0438\u044f \u0410\u041d \u0420\u0422, \u041a\u0430\u0437\u0430\u043d\u044c sabantsev.ipen@gmail.com \u0420\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u0420\u0438\u0441. 1. \u0412\u0441\u0442\u0440\u0435\u0447\u0438 \u0436\u0443\u043a\u043e\u0432 \u0436\u0443\u0436\u0435\u043b\u0438\u0446 \u0438 \u043c\u0435\u0440\u0442\u0432\u043e\u0435\u0434\u043e\u0432 \u0432 \u0438\u0441\u0441\u043b\u0435\u0434\u0443\u0435\u043c\u043e\u043c \u0440\u0435\u0433\u0438\u043e\u043d\u0435 \u0434\u043e \u0438 \u043f\u043e\u0441\u043b\u0435 \u0432\u043d\u0435\u0441\u0435\u043d\u0438\u044f \u0434\u0430\u043d\u043d\u044b\u0445 \u0432 GBIF \u0420\u0438\u0441. 2. \u041d\u0430\u0445\u043e\u0434\u043a\u0438 \u0432\u0438\u0434\u0430 Paradromius linearis (G. A. Olivier, 1795) \u043d\u0430 \u0442\u0435\u0440\u0440\u0438- \u0442\u043e\u0440\u0438\u0438 \u0415\u0432\u0440\u043e\u043f\u044b \u0438 \u0420\u043e\u0441\u0441\u0438\u0438", "label": "poster"}
{"text": "DOIs Should Not Link to Data In August of 2011, the National Academy of Science\u2019s Board of Research Data and Information (BRDI) had a meeting on the topic of \u201cDeveloping Data Attribution and Citation Practices and Standards\u201d. As part of that meeting were various breakout groups to discuss issues that still remained regarding technical, scientific, and socio-cultural issues, the roles and actors that needed to be involved, and how to get additional feedback from the community. The technical breakout group decided that the majority of the technical problems with citing data revolved around establishing the identity of what it was that we were attempting to cite. As such, our recommendations were to push some of the work back onto the data publishers to tell us how scientists should cite their data (to avoid different disciplines applying different rules), establish \u2018data landing pages\u2019 to describe, document and link to the data, and to provide those pages with persistent identifiers such as a DOI. We present here some of the reasons that were discussed about why not to link directly to data, including: recalibration, reaccessioning and other data impermanence, setting context and providing links to documentation, and allowing selection of different packaging formats http://virtualsolar.org/ IN13B-1564 J.A. Hourcl\u00e9 NASA-GSFC (Wyle) joseph.a.hourcle@nasa.gov Data Impermanence: Recalibration / Versioning New processed forms of data create a slightly different problem from outright removal; as one form of the data is deprecated, a new form supersedes it Some projects will generate new calibrations of the data as the sensor degredation is better understood without a fixed release. Some data is released in near-real-time, with a reprocessing pass done after additional calibration tests are run. In the case of NASA\u2019s Solar Dynamics Observatory\u2019s (SDO) Atmospheric Imaging Assembly (AIA), data is available immediately after downlink, reprocessed 4 days later, then again 6 months later, each time improving the precision of the resultant data. Multiple calibrations of the same observation from SOHO/EIT For long-lived projects, the data is not fixed until after the data gathering concludes. The joint NASA/ESA Solar and Heliophysics Observatory (SOHO) was launched on December 2, 1995, with instruments that have been collecting data for almost 18 years and have not generated a \u2018final data product\u2019. Once these better calibrations are available, the older data is obsolete and, in some fields, discarded. Due to a lack of data citation standards, there is no easy way to identify which versions may have been used as part of the scientific record and should be maintaned long-term. Keeping all editions of the data is not cost-effective, and so only the raw data and \u2018final data product\u2019 are archived for the long-term. If people attempt to link to data that has been superseded, the archive has a few choices: Return the original data (or the replacement) We don\u2019t know why someone was following the link: are they doing new research or trying to validate older work? Replacements may be suitable if your identifiers are for the observations (as is done in some Active Archives), but typically DOIs are used for objects with a fixed form and this would not be expected. Redirect to the replacement. This will give a clue that a replacement has been made, but most browsers and automated user agents will redirect without any indication that they did so. Return a message explaining what\u2019s happened. Automated agents may not realize what\u2019s happening. If served as a success (HTTP 200), they may assume it\u2019s the data requested. If served as common redirections (HTTP 301 to 307), most user agents will redirect without displaying the message. HTTP 300 (Multiple Choices) without a Location header is your best option. You need a response is over 1024 bytes to avoid browser rewriting. Data Impermanence: Deaccessioning / Removal If data isn\u2019t actively used by the designated ", "label": "poster"}
{"text": "The highly contagious SARS-CoV-2 virus has generated an unprecedented pandemic with global dramatic public health and socio-economic consequences. Despite the progression of the global use of efficient vaccines, an increased transmissibility of variants of concern (VOC) is predominantly observed. Besides effective vaccination campaigns and new approved antivirals, hundreds of thousand patients have still been admitted to ICU in Europe in the first half of 2022. Passive immunotherapies based on monoclonal antibodies have shown a drop of neutralization potency against VoCs. A polyclonal approach might be effective to neutralize fast-evolving VoCs and prevent worsening medical conditions for hospitalized patients at risks. The main objective of the European EPIC-CROWN-2 consortium is to rapidly assess, in multicentric clinical trials (phase IIa/b) an EMA-authorized antiviral immunotherapy based on potent and broad equine neutralizing anti-SARS-CoV-2 polyclonal F(ab\u2019)2 antibodies in COVID-19 patients, including VOC carriers. Production of equine neutralizing anti-SARS- CoV-2 polyclonal F(ab\u2019)2 antibodies Phase 2a cohort 1: Patient\u2019s enrolment completion Validation of the Safety profile of FBR-002 by the DSMB Phase 2a cohort 2: Ongoing patients' enrolment Belledant A.\u00b9, Luczkowiak J.\u00b3, Delgado R.\u00b3, Rodriguez E.\u2074 , Veas F.\u2075, Giamarellos-Bourboulis E.\u00b2, Herbreteau C.H.\u00b9* \u00b9FAB\u2019ENTECH (Lyon, France), \u00b2HISS Hellenic Institute for the Study of Sepsis, Athens, Greece, \u00b3IMAS12, Instituto de Investigaci\u00f3n Hospital Universitario 12 de Octubre (Madrid, Spain), \u2074BNITM, Bernhard Nocht Institute for Tropical Medicine (Hamburg, Germany), \u2075IRD, Institute of Research and Development (Montpellier, France) *Corresponding Author: scientific.communication@fabentech.com Luczkowiak J, Radreau P, Nguyen L, Labiod N, Lasala F, Veas F, Herbreteau C.H, Delgado R. Potent Neutralizing Activity of Polyclonal Equine Antibodiesagainst SARS-CoV-2 Variants of Concern. J Infect Dis. 2022. DOI: 10.1093/infdis/jiac331 Table . Neutralizing Levels for FBR-002 Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Authentic Clinical Isolates, SARS-CoV-2 Pseudotyped Particles, and Controls and Median Inhibitory Concentrations With Sotrovimaba FBR-002 exhibits significant neutralizing activity against current described VoCs including Omicron subvariants BA.4/5 FBR-002 neutralizing potency x100 as compared in humans after COVID-19 mRNA vaccines FBR-002 neutralizing activity more resilient against VoC than clinically approved mAbs Highly purified polyclonal F(ab')2 fragments Based on a technology developed by Sanofi Pasteur and licensed to Fabentech Standard production process FAB\u2019ENTECH PLATFORM EPIC CROWN-2 CLINICAL TRIAL PROJECT EQUINE POLYCLONAL ANTIBODIES IMMUNOTHERAPY AGAINST COVID-19/SARS-COV2\u2013VOC IN VITRO STUDIES : SARS-COV-2 NEUTRALIZING ASSAYS OF FBR-002 EVOLUTION OF SARS-COV-2 VOC NEUTRALIZING LEVELS METHODOLOGY NEUTRALIZATION OF SARS-COV-2 VOC (FBR-002) KEY STATEMENTS CLINICAL BATCH OF FBR-002 PRODUCTION VALIDATED HIGH NEUTRALIZING POTENCY OF FBR-002 TO SARS COV-2 VOCS IN VIVO EFFICACY OF FBR-002 ONGOING SAFETY PROFILE OF FBR-002 UNDER EVALUATION IN PHASE 2A CLINICAL TRIAL", "label": "poster"}
{"text": "Safe-, sUstainable- and Recyclable-by design Polymeric systems A guidance towardS next generation of plasticS Simon Clavaguera1 on behalf of the SURPASS consortium 1 Universit\u00e9 Grenoble Alpes, CEA LITEN, DTNM, 17 rue des Martyrs 38000 Grenoble, France Background, Motivation and Objectives Concept, Methodology and Implementation simon.clavaguera@cea.fr Project funded by the European Union under the Horizon Europe work programme grant agreement N\u00b0 101057901. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union. Neither the European Union nor the granting authority can be held responsible for them. Acknowledgements and funding information 1. Develop SSRbD alternatives with no potentially hazardous additives through industrially relevant case-studies (TRL3-5) targeting the three sectors representing 70% of the European plastic demand: - Building: bio-sourced polyurethane resins with enhanced vitrimer properties to replace PVC for window frames (\u2265 40% carbon footprint reduction) - Transport: lightweight, therefore less energy-consuming epoxy-vitrimer (\u226530% carbon footprint reduction), as alternative to metal for the train structure, anticipating emerging use of non-recyclable composites. - Packaging: MultiNanoLayered films involving no compatibilizers to replace currently non-recyclable multi-layers films (\u226560% carbon footprint reduction). Plastic waste outlive us on this planet as they take centuries to break down. The hazard of endocrine disruption by leached substances, fast growing and pollution of land, air and water as well as greenhouse gas emissions are only some of the adverse effects of plastic waste on public and environmental health. Still, 70% of plastic waste collected in Europe is landfilled or incinerated. The overall objective of SURPASS project is to lead by example the transition towards more Safe, Sustainable and Recyclable by Design (SSRbD) polymeric materials. The SURPASS consortium will: 2. Optimize reprocessing technologies adapted to the new SSRbD systems to support achievement of ambitious recyclability targets. 3. Develop a scoring-based assessment that will guide material designers, formulators and recyclers to design SSRbD polymeric materials, operating over the plastic\u2019s entire life cycle, including hazard, health, environmental and economic assessment. 4. Merge all data and relevant methodologies in a digital infrastructure, offering an open-access user-friendly interface for innovators. Consortium 1. CEA: Commissariat \u00e0 l\u2019Energie Atomique et aux Energies Alternatives, France 2. IPC: Centre Technique Industriel de la Plasturgie et des Composites, France 3. CIDETEC: Fundacion CIDETEC, Spain 4. LEITAT: Acondicionamiento Tarrasense Associacion, Spain 5. INDRESMAT: Indresmat SL, Spain 6. UGA: Universite Grenoble Alpes, France 7. GEONARDO LTD: Geonardo Environmental Technologies Ltd, Hungary 8. BASF SE: BASF SE, Germany 9. RIVM: Rijksinstituut voor Volksgezondheid en Milieu, Netherlands 10. UNE: Asociacion Espanola de Normalizacion, Spain 11. FhG ICT: Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung EV, Germany 12. WIPAK: WIPAK Gryspeert SAS, France 13. WFO: Waste Free Oceans Europe, Belgium The SURPASS consortium of 13 partners consisting of research and technology organizations and industries will in particular address its results to SMEs, representing more than 99% of enterprises, and therefore has an outstanding potential to contribute to the transition towards green economy", "label": "poster"}
{"text": "Orphan medicines legislation General pharmaceutical legislation 7 May - 30 July 2021 28 Sept. - 21 Dec. 2021 303 answers including 12 public authorities from 9 Member States* 478 answers including 31 public authorities from 15 Member States** IMPROVING ACCESS TO INNOVATIVE MEDICINES: IMPROVING ACCESS TO INNOVATIVE MEDICINES: PROPOSALS FROM NATIONAL AUTHORITIES PROPOSALS FROM NATIONAL AUTHORITIES TO REVISE THE EUROPEAN LEGISLATION TO REVISE THE EUROPEAN LEGISLATION A u r \u00e9 l i e M a h a l a t c h i m y [ 1 ] , F l o r e n c e L a n s o n [ 2 ] , B l a n k a B a r t o s [ 3 ] , F l o r e n c e T a b o u l e t [ 4 ] MAIN PROPOSALS FROM NATIONAL AUTHORITIES Proportionate to the level of UMN (e.g. variable duration of market exclusivity) Focused on neglected therapeutic areas Conditional to certain obligations Be transparent on R&D costs and actual prices Launch in all or most Member States UMN re-evaluated after commercialization Use experiences developped from covid-19 crisis Joint procurement Flexibility in clinical trials conduct On the incentives granted to sponsors On the criteria for orphan designation To be adjusted to avoid \"salami slicing\" (segmenting therapeutic indications) To be taken into account with the severity of the disease (level of unmet medical need - UMN) Prevalence : < 5 in 10,000 persons in the EU To be clarified and graduated Significant benefit : no EU satisfactory method of diagnosis, prevention or treatment, or drug significant benefit Many isolated proposals : difficult to identify a consensus among the authorities Request of better cooperation between all agencies and more EMA support BUT emphasis on respecting the EU and Member States competences sharing > Orphan single status transformed into a mosaic of statuses Complexities : how to quantify ? which indicators ? > Future EU considerations of national authorities proposals and answers from other respondents ? Patient access to medicines Health systems sustainability Innovation support EU legislation Objectives to be balanced 80% of rare diseases are of genetic origin in the EU = Many advanced therapies have obtained the orphan medicine status under European regulation (EC) n\u00b0 141/2000 of 16 December 1999 on orphan medicial products Provides orphan designation and incentives (market exclusivity for 10 years) Ensure the relevance of incentives granted to industry (to avoid abuses) Reward risk-taking and innovation more Improve equitable patient access in the EU Needs to be revised. Why? Public consultations on revision of European legislation DISCUSSION AND CONCLUSION [1] Permanent Researcher in law at the French National Centre for Scientific Research (CNRS, research fellow), Law Faculty, UMR 7318 International, Comparative and European law (DICE) CERIC, CNRS, Aix Marseille University, Toulon University, Pau & Pays de l\u2019Adour University, Aix-en-Provence, 13628, France. ; [2] CERPOP (Center for Epidemiology and Research in POPulation health), UMR 1295 Inserm, University of Paul Sabatier- Toulouse 3, Toulouse, 31062, France. ; [3] PhD Student in law, CREDIMI, University of Burgundy, Dijon, 27877, France. ; [4] Professor in Pharmaceutical Law and Health Economics, CERPOP, UMR 1295 Inserm, University of Paul Sabatier- Toulouse 3, Toulouse, 31062, France. Acknowledgement: This work has been supported by ANR-funded I-BioLex project (ANR-20-CE26-0007-01, coord. A. Mahalatchimy). *AT, DE, DK, ES, FI, FR, HU, NL, SE ; **AT, BE, CZ, DE, DK, EE, ES, FI, FR, HU, IS, MT, NL, PT, SE", "label": "poster"}
{"text": "Rapid Characterisation of hERG Kinetics Using Optimised Protocols on a High-Throughput System Chon Lok Lei1, Michael Clerx1, David J. Gavaghan1, Liudimila Polonchuk2, Gary R. Mirams3, Ken Wang2 1. Computational Biology, University of Oxford, UK; 2. Pharma Research & Early Development, Roche, Switzerland; 3. Centre for Mathematical Medicine & Biology, University of Nottingham, UK chon.lei@cs.ox.ac.uk [1] Beattie et al. (2018) J. Physiol. [2] Traynelis (1998) J. Neurosci. Methods [3] Sherman et al. (1999) Biophys. J. 0 2 4 6 8 10 12 14 100 0 Voltage [mV] A Calibration B 0 2 4 6 8 10 12 14 20 0 20 Current [A/F] data model fit to data Time [s] Validation 1 Validation 2 0.00 0.05 0.10 0.15 0.20 0.25 0.30 0.35 0.40 50 0 Voltage [mV] Validation 3 0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 50 0 0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 50 0 0.00 0.05 0.10 0.15 0.20 0.25 0.30 0.35 0.40 0 5 10 Current [A/F] 0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 Time [s] 0 10 20 0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0 5 10 Voltage [mV] 0.0 0.2 0.4 0.6 0.8 1.0 1.2 1.4 50 0 0.00 0.25 0.50 0.75 1.00 1.25 1.50 1.75 Time [s] 50 0 Voltage [mV] Time [s] Current [A/F] 0.0 0.2 0.4 0.6 0.8 1.0 1.2 1.4 0 10 data model prediction 40 20 0 20 40 0.0 0.5 1.0 Normalised Current Voltage [mV] Validation 4 Validation 5 0 1 2 3 4 p1 0 2 4 1e2 40 60 80 p2 0 1 2 0.0 0.1 0.2 0.3 0.4 0.5 p3 0 1 2 1e3 30 40 50 60 70 p4 0.00 0.25 0.50 0.75 1e1 200 300 400 500 600 p5 0.0 0.5 1.0 1.5 Normalised frequency 1e 1 10 20 30 40 50 p6 0 1 2 3 20 40 60 p7 0.0 0.5 1.0 1.5 20 25 30 35 40 p8 0 1 2 3 0 2000 4000 6000 gKr 0 1 2 1e 1 1 2 3 4 5 6 noise 0.0 0.5 1.0 1.5 1e2 0 2 4 1e 4 0 2 4 6 1e 1 0 1 2 3 1e 2 0.0 0.5 1.0 1e1 0 2 4 1e 2 0 2 4 1e 3 0 2 4 Probability density 1e 2 0 1 2 3 1e 2 0.0 0.5 1.0 1e 1 3.5 Model Parameters Correlation 3.3 Variability Across Experiments 3.2 Model Validation 3.1 Experimental Design / Model Training/Fitting Hierarchical Model Structure 1. Introduction Variability in hERG Kinetics References Fig 2: An optimised protocol that is designed for high throughput machine to recover model parameters. It shows the actual experimental measurement and the fitted model. Fig 3: Independent experimental measurements of the same cell to use as model validation. Here we used both 'traditional' protocols (Validation 4, 5) and new physiologically inspired [1] protocols (Validation 1-3) which are the AP-like, EAD-like and DAD-like waveforms. We repeated the same experiment on the same cell-line and recorded 65 individual cell measurements. Can we capture experiment-to- experiment variability? Fig 5: A hierarchical Bayesian model (HBM) was used to capture experiment- to-experiment variability. Marginal distributions of each experiment are shown, which reveal the variability between experiments. The posterior predictive distributions from the HBM are shown in red. Hodgkin-Huxley formulation 2. Cardiac hERG Channel Model 3.4 Consideration of Experimental Error Model The above analyses have assumed experiments were done 'perfectly'. That is we have assumed our input of the command voltage V was what the cell experienced as the membrane voltage Vm during the experiment. However, this might not be exact [2, 3]. Therefore we have also considered the possible error source in the experiment, as error model, to give: where 'mechanistic model' is our IKr model and 'noise model' is a simple Gaussian/white noise model. Fig 6: The 95% C.I. contour plots of the inferred covariance matrix, together with each parameter values. It shows a compar- ison of the parameter varia- bility (blue) and the effect of the voltage error model (red) on synthe- tic data. Fig 5: A schematic of the full hierarchical Bayesian model, which is a multi-level modelling technique that combines individ- ual measures (lower level) as a group (top level). Prior distributions are specified for the , , . This allows us to combine multiple experiments into one causal structure. Notation: 4. Experimental Methods This is not the end! Acknowledgements Fig 1: A simp", "label": "poster"}
{"text": "Towards a datafication of Antwerp street life? Co-creating a dataset of 100.000 pages of handwritten police reports (1876-1945) INCIDENT BOOKS OF ANTWERP = Reports of daily and nightly police patrols on district level dealing with prosecuted and non- prosecuted crime \u25bbSerial character = consistent registration over time of \u2022 personal data of people involved: name, profession, date and place of birth, place of residence \u2022 incident: location, date, time of day, detailed description \u2022 follow-up of the incident Coming soon: open access publication of dataset and HTR-model Contact: Lith Lefranc (Lith.Lefranc@UAntwerpen.be) PhD advisors: Ilja Van Damme and Mike Kestemont RESEARCH POTENTIAL \u25bbRare window on bottom-up practices and lived experiences of ordinary people \u25bbData-driven approach to history of local policing, working-class history, history of mentalities, gender and sexuality history, history of the everyday, youth and family history\u2026 \u25bbDataset specifics \u2022 289 incident books \u2022 97,498 images \u2022 \u00b1 30,500,000 words of (automatic) transcriptions in various file formats \u2022 Languages: French and Dutch \u2022 11 districts of Antwerp \u2022 Time span: 1876-1945 Training Material #Words CER Ground truth 78,581 12.3% Ground truth + best 1/3 students 370,206 9.0% Ground truth + best 2/3 students 734,857 8.0% Ground truth + all students 978,672 7.9% HANDWRITTEN TEXT RECOGNITION \u25bbChallenges: \u2022 Numerous different handwritings \u2022 Bilingual: French + Dutch \u2022 Complex layout (esp. skewed text) \u25bbHTR-model training: combination of gold with semi-gold standard training material (students) \u2013 created in Transkribus \u25bbError analysis: \u2022 Exclusion of skewed text \u2022 Exclusion of punctuation, capital letters, whitespace in CERberus Relaxed CER: 4.7% 0 5000 10000 15000 20000 25000 30000 1876-1882 1883-1889 1890-1896 1897-1903 1904-1910 1911-1917 1918-1924 1925-1931 1931-1938 1939-1945 Number of pages Sample periods Distribution by sample period 1 May 1885 Mr Sergoynne draw up an official report D At 9 \u00bd hours in the evening I saw that the maid from the house N\u00b0 57 in the Leopoldst was beating rugs against the wall of the guesthouse when I came over she ran away inside the house and didn\u2019t come outside any more (she caused a flood of dust) Broes, Dymphna, 16 years, born in Minderhout, maid, residing in Leopoldstr 57 Because she was so young and she didn\u2019t know better, I didn\u2019t follow up on this.", "label": "poster"}
{"text": "Correlations in molecular content of oxygen-rich AGB and RSG stars Sofia Wallstr\u00f6m1, Leen Decin1, Carl Gottlieb2, Holger M\u00fcller3, Ta\u00efssa Danilovich1, Fabrice Herpin4, and the ATOMIUM collaboration5 1. Institute of Astronomy, KU Leuven, Belgium. 2. Harvard Smithsonian Center for Astrophysics, Cambridge, Massachusetts, USA. 3. I. Physikalisches Institut, Universit\u00e4t zu K\u00f6ln, Germany. 4. Laboratoire d\u2019astrophysique de Bordeaux, Universit\u00e9 Bordeaux, France 5. https://fys.kuleuven.be/ster/research-projects/aerosol/atomium/atomium Background The ATOMIUM ALMA large project aims to establish the dominant physical and chemical processes in the winds of oxygen-rich evolved stars over a range of ini@al stellar masses, pulsa@on behaviours, mass-loss rates, and evolu@onary phases. Through high-resolu@on (~0.025\" - 0.05\") observa@ons in bands between 214 and 270 GHz, we have detected 286 molecular lines of 23 di\ufb00erent molecules and their isotopologues, in vibra@onal states up to v=5. The eventual unravelling of the complex chemistry of these sources will provide astrochemical knowledge that will strongly impact research on supernovae, protostars, interstellar clouds, ac@ve galac@c nuclei, etc. \u2014 environments in which it is far more di\ufb03cult to grasp the dust nuclea@on process. As a star@ng point for the chemical analysis, we have calculated Pearson's linear correla@on coe\ufb03cients between the molecular content of each source and its (circum)stellar parameters: mass-loss rate, expansion velocity, and pulsa@on type. Ini.al results We see some expected correla@ons with mass-loss rate: a higher wind velocity and molecular tracers of dense winds such as H2S, as well as the rarer Al-bearing molecules. Lower wind velocity, conversely, is correlated with the detec@on of H2O and to a lesser extent OH. Mira pulsator sources are correlated with detec@ons of a somewhat random list of molecules: SiS, CS, PO, AlF, and KCl. The metal oxides PO, TiO, and AlO are well correlated, as expected, though TiO2 is not. AlOH is beaer correlated with the metal halides, which are also nicely correlated with each other, with the excep@on of KCl. KCl also shows no correla@on with mass-loss rate, unlike the other metal oxides and halides. However, these outlier molecules tend to have fewer and weaker detected lines, which may explain the observed trends. All results should be treated as preliminary! Note that we also detect more carbonaceous molecules, such as HC3N and SiCC, as well as the nitrogen-bearing SiN, but only in the singular S-type star W Aql and hence they are not included in the correla@on table. VX Sgr and W Aql are the most line rich sources in our sample, with ~5.5 and ~3.8 lines/GHz, respec@vely. Correla.ons between sources: Table of linear correla@on coe\ufb03cients, colorized by value from green (1.0 = perfect correla@on) to pink (-1.0 = perfect an@-correla@on), calculated using values of mass-loss rate and expansion velocity, and designa@on as 0 or 1 in pulsa@on type (Mira or other) and molecular content (line detec@on at a 3\u03c3 level) Source Puls MLR vWind S Pav SRa 8.0E-08 9 T Mic SRb 8.0E-08 4.8 U Del SRb 1.5E-07 7.5 R Hya Mira 2.0E-07 12.5 RW Sco Mira 2.1E-07 11 SV Aqr LPV 3.0E-07 8 V PsA SRb 3.0E-07 14.4 U Her Mira 5.9E-07 15 pi Gru SRb 7.7E-07 30 AH Sco SRc 1.0E-06 23 W Aql Mira 3.0E-06 17.2 R Aql Mira 3.5E-06 8 KW Sgr SRc 5.0E-06 27 GY Aql Mira 6.0E-06 13.6 IRC-10529 Mira 1.0E-05 13 IRC+10011 Mira 1.0E-05 23 VX Sgr SRc 6.1E-05 24.3 Source table: The ATOMIUM sample of AGB and RSG stars, along with their pulsa@on type, mass-loss rate (in solar masses per year) and expansion velocity (in km/s), taken from the literature.", "label": "poster"}
{"text": "Shea Jiun Choo1, Sabariah Noor Harun2, Balamurugan Tangiisuran2, Chee Tao Chang3, Mohd Faiz Abdul Latif,4 Nor Aida Sanusi5 C-06 1.Taiping Hospital 2. School of Pharmaceutical Sciences, Universiti Sains Malaysia 3. Clinical Research Centre, Raja Permaisuri Bainun Hospital, 4. Taiping Health Clinic 5. Pharmaceutical Services Division, Perak State Health Department A MULTICENTRE RETROSPECTIVE COHORT STUDY ON TREATMENT OUTCOME OF VARENICLINE Characteristics (n=114) Frequency (%) Treatment duration (week), in mean \u00b1 SD 8.8 \u00b1 3.3 Smoking abstinence rate Successful Unsuccessful 68 (59.6) 46 (40.4) Type of adverse events Frequency (%) Cardiovascular related Hospitalization Angina pectoris 2 (1.8) 1 (0.9) Neuropsychiatric related Altered behaviour Auditory hallucination 2 (1.8) 1 (0.9) Others Increased appetite Dizziness Dry mouth Nausea Abnormal dreams Insomnia Stomach discomfort Others 19 (16.7) 18 (15.8) 12 (10.5) 10 (8.8) 9 (7.9) 9 (7.9) 6 (5.3) 21 (18.5) Characteristics (n=114) Frequency (%) Age (years), in mean \u00b1SD 46.0 \u00b1 14.4 Gender Male Female 104 (91.2) 10 (8.8) Ethnic Malay Chinese Indian 70 (61.4) 17 (14.9) 27 (23.7) Number of cigarette smoked per day (sticks), in mean \u00b1 SD 17.0 \u00b1 11.3 Duration of smoking (years), in mean \u00b1 SD 26.6 \u00b1 14.9 Fagerstrom score 0 to 3 (Low dependence) 4 to 5 (Moderate dependence) 6 to 10 (High dependence) 42 (36.8) 28 (24.6) 44 (38.6) Attempts to quit Yes No 79 (69.3) 35 (30.7) Table 4: Logistic regression model predicting successful smoking abstinence Variables Adjusted odd ratio 95% CI P-value Number of cigarette/day 1.102 0.929, 1.103 0.785 Duration of smoking 0.800 0.639, 1.003 0.053 Fagerstrom score High Low-to-moderate Reference 1.033 0.164, 6.519 0.972 Without quit attempt 0.330 0.066, 1.657 0.178 Readiness to quit Pre-contemplation & contemplation Preparation & action Reference 5.145 1.005, 26.328 0.049 Treatment duration 2.445 1.735-3.445 <0.001 Adverse events 0.096 0.014, 0.644 0.016 Withdrawal symptoms 0.032 0.016, 0.835 0.032 NMRR-18-2984-44113 (IIR) ACKNOWLEDGEMENT We would like to thanks the Director General of Health, Ministry of Health Malaysia for his approval to present this study. REFERENCES 1. Cahill, K., et. al. 2013. Pharmacological interventions for smoking cessation: an overview and network meta\u2010analysis. Cochrane database of systematic reviews, (5). 2. Ware, J.H., Vetrovec., et al. 2013. Cardiovascular safety of varenicline: patient-level meta-analysis of randomized, blinded, placebo-controlled trials. American Journal of Therapeutics, 20(3), pp.235-246. 3. Anthenelli, R.M., et.al 2016. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. The Lancet, 387(10037),pp.2507-2520. Table 1: Demographic characteristics of patients Table 3: Adverse drug events experienced by patients Table 2: Treatment duration and rate of smoking abstinence", "label": "poster"}
{"text": "A new 2 km Sea Surface Temperature Atlas of the Australian Regional Seas (SSTAARS) Summary We use 25 years of Advanced Very High-Resolution Radiometer (AVHRR) data from NOAA Polar Orbiting Environmental Satellites received by six Australian and two Antarctic receiving stations to construct a detailed climatology of sea surface temperature (SST) at 20 cm depth around Australasia. \u2022 Raw scans have been accurately navigated \u2022 Only night-time nearly cloud-free data are used to reduce diurnal bias and cloud contamination \u2022 Irradiances have been processed and fitted to in situ drifter data following international GHRSST protocols to help reduce instrument bias \u2022 A pixel-wise (2km) climatology (with four annual sinusoids) and linear trend are fit to the data using a robust fitting technique \u2022 Monthly non-seasonal percentiles are also derived Validation \u2022 Used temperatures from coastal tide gauges and wave-rider buoys, not used to de-bias the satellite data (Figure 1a) \u2022 Climatology based on in situ observations was compared to SSTAARS \u2022 The major driver of difference is the distance between the in situ site and the nearest Atlas pixel (Figure 1b). \u2022 The more offshore wave-rider sites show very good agreement with the Atlas as they can be most closely collocated with an Atlas pixel \u2022 For co-locations within 3km, RMS errors are 0.2o C or less, and within 1km, 0.1o C or less, comparable to the average drifter matchup errors Susan E. Wijffels1,2, Helen Beggs3, Christopher Griffin3, John F. Middleton4, Madeleine Cahill1, Edward King1, Emlyn Jones1, Ming Feng1, Jessica A. Benthuysen5, Craig R. Steinberg5 and Phil Sutton6 Key phenomena revealed \u2022 Indonesian Throughflow warm advection (Figures 4 and 5) \u2022 Summer tidal drawdown over tropical shelves (Figures 6 and 7) \u2022 Tidally-driven reef-flat mixing (Figures 6 and 7) \u2022 Boundary current flows and their seasonality (Figures 8 and 9) \u2022 Cross-shelf gradients of variance due to mesoscale eddies (Figure 9) \u2022 Suppression of the annual cycle by warm advection along the Lleeuwin Current pathway (Figures 8 and 9) Data Access SSTAARS Atlas files: https://portal.aodn.org.au/search?uuid=79c8eea2-4e86-4553-8237-4728e27abe10 IMOS AVHRR daily night-time L3S data used as input: https://portal.aodn.org.au/search?uuid=79c8eea2- 4e86-4553-8237-4728e27abe10 Figure 1: a) Locations of long and relatively continuous near surface in situ temperature records from either coastal tide gauge sites (SL) or offshore wave-rider sites (WR); b) RMS difference in the seasonal cycle between the in situ and Atlas estimates as a function of distance between the in situ measurement site and the nearest Atlas pixel. 1 CSIRO Oceans and Atmosphere, GPO Box 1538 Hobart, TAS 7001 Australia 2Woods Hole Oceanographic Institution, MS #29, 266 Woods Hole Road, MA 02540, USA 3 Bureau of Meteorology, Docklands, VIC 3008, Australia 4 South Australian Research and Development Institute, West Beach, SA 5024, Australia 5 Australian Institute of Marine Science, Townsville, QLD 4810, Australia 6NIWA, Wellington, New Zealand Coverage \u2022 The coverage for June and December is shown in Figure 3 in observation count per pixel \u2022 Sampling is very seasonally dependent, due to cloudiness \u2022 Pixels near Australia have more observations, with sampling dropping off with distance from Australian satellite receiving stations due to reduced reception of direct broadcast NOAA satellite data by these receivers. Figure 2: Estimates of the linear SST trend from 3/1992-12/2016: a) from the IMOS SST archive and b) from the NOAA OI V2 weekly SST. Units are oC/decade and the contour interval is 0.2\uf0b0C/decade. Grey stippled regions mark where the trend is smaller than 2 times the standard error (95% significance level). 25 Year Trends Figure 4 (top left): Climatological SST from the Atlas for the Indonesian Seas shown every 2 months. The colour scale is adaptive and changes every month to help better reveal spatial contrasts. Grey contours mark the 50m (thin) and 200m (thic", "label": "poster"}
{"text": "Potential CO2 storage sites Stenlille \u2022 The reservoir occurs within a domal closure and is overlain by a 300 m thick clay sequence of the Fjerritslev formation. \u2022 A 140 m thick upper Triassic Gassum sandstone formation 1500\u2013 1600 m below the surface. \u2022 As of 2017, there are 14 injection and production wells as well as 6 observation wells. \u2022 Smooth operation of the natural gas storage site since 1989. \u2022 The geological setting at Stenlille is assumed to represent a good analog to the Havns\u00f8 structure since similar lithologies and burial depths for the Gassum formation are expected. \u2022 The average porosity (25%) and permeability (250 mD) in the Gassum sandstone reservoir at Stenlille represent good conditions for geological CO2 storage. \u2022 The Stenlille dataset is the most comprehensive onshore dataset in Denmark (cuttings descriptions, core analysis data, wireline logs, well completions reports, well test reports, seismic data, geochemical data, and historical records of injection and production rates of natural gas, as well as bottomhole and wellhead pressures and temperatures). Havns\u00f8 \u2022 One of the most prospective CO2 storage sites in Denmark. \u2022 Proximity of large CO2 emission sources: a biomass-fired power plant and a refinery close to Kalundborg; supplementary CO2 point sources in Copenhagen. \u2022 No wells have been drilled and only low-quality seismic data is available (new seismic was acquired in August-October 2022). Reservoir models \u2022 CO2-water isothermal model without geochemical reactions \u2022 Phase properties are modelled as functions of pressure. Stenlille \u2022 The model, covering approximately 7,760 x 3,570 x 137 meters, contains 119,634 active cells with properties, adjusted to represent faults and fractures. \u2022 The reservoir consists of 6 zones, separated by impermeable layers. \u2022 The model is history matched to natural gas injection/production and pressure data, which makes it a good candidate to model CO2 injection. Havns\u00f8 \u2022 The reservoir model is based on the Top Gassum map, obtained from seismic interpretation. \u2022 A uniform thickness reservoir of approximately 20,000 x 15,000 x 150 m has 4,959,998 active cells. \u2022 The distribution of rock properties follows the suggested depositional pattern from Stenlille. In a net-zero CO2 emission economy, the CO2 transportation and storage networks will need to accommodate fluctuations in CO2 feed- flows. This calls for a need to assess different strategies for temporary storage of CO2. The objective of the present work is to evaluate the efficiency of temporary CO2 storage in saline aquifers for the case of two geological sites in Denmark, Stenlille and Havns\u00f8. Specifically, we study the sensitivity of CO2 recovery factor with regards to the parameters of the CO2-water relative permeabilities and capillary pressures. The results of the sensitivity study demonstrate a critical role of rock-fluid interactions and accurate reservoir characterization on the estimates of CO2 recovery. In all considered injection/production scenarios, the efficiency of temporary CO2 storage does not exceed 30%; achieving this recovery factor is only possible if a large amount of CO2 is injected in the reservoir for permanent storage (several hundred thousand tons for the considered cases). The duration of this initial CO2 injection is of the order of years so that the caprock integrity will not be compromised. Sensitivity study on CO2 recovery during temporary storage \u2022 Sampling the parameters of the saturation functions within the ranges from the literature. \u2022 Quantifying the impact of uncertainty in relative permeability and capillary pressure on the CO2 recovery factor (RF) during temporary storage. \u2022 Modelling CO2 injection in a vertical well, located at the top of the Stenlille and Havns\u00f8 structures. \u2022 Injection for 10 years with a constant bottomhole pressure control, followed by 10 years production with the constant topside pressure control. Stenlille \u2022 A large spread in CO2 recovery factors, depending", "label": "poster"}
{"text": "Seit ihrer Gr\u00fcndung im Jahr 1661 ist die Staatsbibliothek zu Berlin f\u00fcr die \u00d6ffentlichkeit zug\u00e4nglich. In dieser Tradition sowie im Bewusstsein ihrer besonderen historischen Verantwortung steht die Staatsbibliothek zu Berlin zu ih- rer Verpflichtung, wissenschaftliches Wissen der Gesellschaft unbeschr\u00e4nkt und gleichberechtigt zur Verf\u00fcgung zu stellen. Als Einrichtung der Stiftung Preu\u00dfischer Kulturbesitz hat sie die Berliner Erkl\u00e4rung \u00fcber den offenen Zugang zu wissenschaftlichem Wissen unterzeichnet. Deren Ziel ist es, Open Access zu be- f\u00f6rdern \u2013 also sowohl den offenen Zugang als auch die freie Nachnutzung von wissenschaftlichen Wissensbest\u00e4nden einschlie\u00dflich der diesen zugrunde liegenden Daten. In ihrer Funktion eines Zentrums der \u00fcberregionalen Literatur- und Informationsversorgung sowie als gr\u00f6\u00dfte wissenschaftliche Universal- bibliothek in Deutschland hat die Staatsbibliothek zu Berlin Open Access als ein zukunftsweisendes Handlungsfeld in den Blick genommen und zum festen Be- standteil ihrer strategischen Weiterentwicklung gemacht. Nicht zuletzt auch im Kontext der im Oktober 2015 beschlossenen Open Access-Strategie f\u00fcr Berlin hat die Staatsbibliothek zu Berlin verschiedene Themenbereiche identifiziert, in denen sie Open Access unterst\u00fctzen kann. Sie engagiert sich daher f\u00fcr die \u0083\u0083 Digitalisierung und offene Zug\u00e4nglich- machung ihrer urheberrechtsfreien Best\u00e4nde, \u0083\u0083 Bereitstellung geeigneter Infrastrukturen f\u00fcr das Publizieren im Open Access, \u0083\u0083 Sicherung und Erschlie\u00dfung amtlicher Open Access-Ver\u00f6ffentlichungen, \u0083\u0083 Freigabe der von ihr erstellten bibliographischen Metadaten an die Allgemeinheit, \u0083\u0083 zielgruppenspezifische Beratung zu Fragen von Open Access und Open Science, \u0083\u0083 Transformation des wissenschaftlichen Publikationssystems. DIGITALISIERUNG UND OFFENE ZUG\u00c4NGLICHMACHUNG URHEBERRECHTSFREIER BESTANDSSEGMENTE FREISTELLUNG BIBLIO- GRAPHISCHER METADATEN \u0083\u0083 verantwortet mit der Zeitschriftendatenbank in Koope- ration mit der Deutschen Nationalbibliothek den welt- weit gr\u00f6\u00dften Katalog f\u00fcr den Nachweis von Periodika \u0083\u0083 \u00fcbergibt alle kooperativ erstellten Titeldaten der Zeit- schriftendatenbank als maschinenlesbare Linked Open Data der Public Domain \u0083\u0083 stellt ihre eigenen Katalogisierungsdaten unter der Cre- ative Commons-Lizenz CC0 der Allgemeinheit zur be- liebigen Nutzung zur Verf\u00fcgung BEREITSTELLUNG VON INFRASTRUKTUREN F\u00dcR DAS PUBLIZIEREN IM OPEN ACCESS SICHERUNG UND ERSCHLIESSUNG AMTLICHER OPEN ACCESS- VER\u00d6FFENTLICHUNGEN \u0083\u0083 ist Depotbibliothek f\u00fcr Dokumente internationaler Organisationen sowie offizielle Sammelstelle f\u00fcr Publikationen \u00f6ffentlich- rechtlicher Einrichtungen der Bundesrepublik Deutschland \u0083\u0083 setzt sich in dieser Funktion f\u00fcr die langfristige Zug\u00e4nglichkeit amtlicher elektronischer Publikationen im Open Access ein MITGESTALTUNG DER TRANSFORMATION DES WISSENSCHAFTLICHEN PUBLIKATIONSSYSTEMS \u0083\u0083 ist Teil des Finanzierungskonsortiums Knowledge Unlatched, das die Publikation sozial- und geisteswissenschaft- licher Monographien im genuinen Open Access erm\u00f6glicht \u0083\u0083 bekennt sich zum Ziel der Transformation des subskriptionsbasierten wissenschaftlichen Publikationssystems \u0083\u0083 spricht im Rahmen der Schwerpunktinitiative Digitale Information der Allianz der deutschen Wissenschaftsorgani- sationen Empfehlungen aus \u2013 u.a. zur Schaffung eines wissenschaftsad\u00e4quaten Open Access-Publikationsmarkts \u0083\u0083 verhandelt im Auftrag von Bibliotheken und Universit\u00e4ten aus ganz Deutschland \u00fcberregionale Lizenzen f\u00fcr elektronische Informationsangebote \u2013 unter Ber\u00fccksichtigung m\u00f6glichst liberaler Zweitver\u00f6ffentlichungsrechte ZIELGRUPPENSPEZIFISCHE BERATUNG ZU FRAGEN VON OPEN ACCESS UND OPEN SCIENCE \u0083\u0083 informiert regelm\u00e4\u00dfig Forschende, Studierende sowie die interessierte \u00d6ffentlich- keit \u00fcber den gegenw\u00e4rtigen Strukturwandel der Wissenschaftskommunikation \u0083\u0083 organisiert u.a. Beratungsangebote zum wissenschaftlichen Publizieren, Workshops zum Forschungsdatenmanagement und Gastvortr\u00e4ge zu Open Science-Themen \u0083\u0083 engagiert sich mit ihren", "label": "poster"}
{"text": "COOPERATION POSTER CREATORS \u201cRetro-editing\u201d : The edition of an edition of the Karl Kraus legal papers IN THE PROJECT \u201cINTERTEXTUALITY IN THE LEGAL PAPERS OF KARL KRAUS. A SCHOLARLY DIGITAL EDITION\u201d, THE LEGAL PAPERS OF THE AUSTRIAN SATIRIST KARL KRAUS (1874- 1936) ARE BEING EDITED AND WILL BE PROVIDED DIGITALLY AND CONTEXTUALIZED WITH KRAUS\u2019 OEUVRE AS A WHOLE. IN THIS POSTER, THE DIGITIZATION AND EDITING PROCESS OF THE PROJECT ARE DESCRIBED. AS THE PRECONDITIONS OF THIS DIGITAL EDITION ARE QUITE UNIQUE, THE POSTER FOCUSES ON THE PROJECT\u2019S SPECIFIC INITIAL SITUATION, THE AVAILABLE MATERIAL, AND ITS PROCESSING AS WELL AS ON THE AIMS, GOALS, AND THE INTENDED OUTCOME (I.E. THE PLATFORM PROVIDING ACCESS TO THE DIGITAL EDITION) OF THE PROJECT. Vanessa Hannesschl\u00e4ger Austrian Centre for Digital Humanities / Austrian Academy of Sciences vanessa.hannesschlaeger@oeaw.ac.at INTERTEXTUALITY IN THE LEGAL PAPERS OF KARL KRAUS : A DIGITAL SCHOLARLY EDITION FWF project no. P 31138-G30 Introduction: Historical context While the Austrian Karl Kraus (1874-1936) is most commonly perceived as a satirist, writer, and editor of the magazine Die Fackel, his intensive preoccupation with justice was often observed and Walter Benjamin even declared: \u201cNo one will understand this man, unless one realises, that everything, without exception, language and purpose, for him happens in the sphere of law.\u201d[1] Although Kraus\u2019 attitude towards the courts in the Habsburg period had been predominantly critical, the constitutional reform of the Austrian Republic in 1919 and the abolition of death penalty marked a decisive break for the author. He especially welcomed the reform of the Press Law of 1922, which marked the beginning of a growing fondness for litigation. In the same year, Oskar Samek became his lawyer. In the course of the following 15 years (until Kraus\u2019 death), they were involved in over 200 court actions together. Despite of Kraus\u2019 commitment to the law, the influence legal proceedings had on his satire and the other way round was barely thoroughly researched \u2013 which was on the one hand due to the fact that cultural and literary historians often shy away from the interpretation of legal documents. Only Reinhard Merkel, a professor of criminal law, attempted to understand the connection of \u201cStrafrecht und Satire\u201d in Kraus\u2019 Fackel from a jurisprudential point of view.[2] The second reason for the lack of research in this area is that the complex history of the Kraus papers, which were split up into several personal collections and taken to exile by Kraus\u2019 (often jewish) friends and associates when they were forced to leave Austria during the time of the Nazi regime, was responsible for the long- lasting unavailability of the material documenting Kraus\u2019 involvement with the law. The project described in this paper aims to bridge this gap by (re-)editing the papers documenting Kraus\u2019 and Samek\u2019s actions and making them available in an open access / open data / open source digital edition. Karl Kraus and Oskar Samek in court. The Kraus legal papers at the Vienna City Library. Initial position and starting point The material documenting Kraus\u2019 and Samek\u2019s court actions is held by the Vienna City Library. As this corpus consists of roughly 8000 sheets of paper, transcribing and editing all these documents in the course of a three year project with three persons (i.e. full time equivalents) staff would be unfeasible. Luckily, transcription is only a minor part of the project members\u2019 tasks: In 1995, Hermann B\u00f6hm published the records of cases from the Karl Kraus papers as a \u2018mixed edition\u2019 (\u201cMischedition\u201d) in four volumes[3] (of roughly 300 pages each). However, B\u00f6hm made a number of editorial decisions which are today out of date and not suited for a digital format, which is why a new edition of this material has become a desideratum among Kraus researchers as well as a wider research community interested in historical legal documents. While B\u00f6hm did a trem", "label": "poster"}
{"text": "Implementation of the \u201cEssential-use\u201d concept in chemical regulations Romain Figui\u00e8rea, Zhanyun Wangb, and Ian T. Cousinsa a: Department of Environmental Sciences, Stockholm University, SE-10691 Stockholm, Sweden b: Empa \u2013 Swiss Federal Laboratories for Materials Science and Technology, 9014 St. Gallen, Switzerland \u2022 Derogations refer mainly to the \u201cavailability of alternatives\u201d component of the essential-use concept. \u2022 Category \u201cOthers reasons\u201d can be divided into two sub-categories: \u2022 Reasons for which the essential-use concept would not affect the regulatory outcome, i.e., because the use already regulated, the use being out of scope, restriction not enforceable for the specific use, or substance found as impurities in the specific use; \u2022 Reasons for which the essential-use concept could affect the outcome, i.e., because negligible risk from the use, or the restriction costs outweigh the benefits, mentioned for ~20% of the derogations. Results Acknowledgements This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement No 101036756. Partners Background Methods In the Montreal Protocol, a use is essential only if (A) it is necessary for the health and safety, or is critical for the functioning, of society; and (B) there are no available safer, technically and economically feasible alternatives. The EU Chemicals Strategy for Sustainability stipulates implementation of the essential-use concept under REACH to guide phase-out of the most harmful substances. Aims of the study To determine (1) whether the existing restriction of uses of harmful chemicals processes refer to elements of the essential-use concept; and (2) whether process changes are necessary to implement the concept in the decision-making. Analysis of the decisions on derogations to restrictions under Stockholm Convention and REACH processes following the READ approach (Dalglish et al. (2020)) to determine if relevant information to perform essential-use assessment was available. Lessons-learnt \u2022 No major changes in the REACH Restriction process are needed to implement the essential-use concept. \u2022 Previous decisions on derogations have been mainly based on the availability of alternatives. \u2022 The essential-use concept can bring a new perspective in decision- making. Components of the essential-use concept mentioned in decision-making on derogations to previous restrictions *: See separate section on REACH Authorisation process References: EU (2020), https://ec.europa.eu/environment/pdf/chemicals/2020/10/Strategy.pdf; Dalglish et al. (2020), DOI: 10.1093/heapol/czaa064; EU (2024), https://environment.ec.europa.eu/publications/communication-essential-uses-chemicals_en Contact romain.figuiere@aces.su.se REACH AUTHORISATION PROCESS \u2022 Authorisations are granted if (1a) risk is adequately controlled, or (1b) costs of ceased use outweigh the benefits, and (2) there no suitable alternatives available to the applicant (\u201cAvailability of alternatives\u201d component) \u2022 Further work is needed to determine if enough information is provided in the applications to evaluate if the technical function is needed in final products, and whether it would fulfil the criteria to be considered as necessary for society \u2022 For 20 applications, the European Commission did not grant authorisation for part of the use applied for where \u201cthe specified key functionality is not necessary for the use\u201d (\u201cTechnical function\u201d component) \uf0fcIs the technical function needed in the final product? Technical function \uf0fcDoes the use fulfil one of the criteria for being critical for society? Necessity for society \uf0fcAre acceptable alternatives lacking? Availability of alternatives Overview of the assessment of essentiality of a use as proposed by the European Commission 2% 15% 58% 40% 8% 15% 31% 88% 5% 100% 100% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Technical function Necessity for society Availability of alternatives Other reasons REACH Authorisa", "label": "poster"}
{"text": "1Departamento de F\u00edsica de la The lithium-age relation: Calibration with open clusters and associations Acknowledgments: Based on data products from observations made with ESO Telescopes at the La Silla Paranal Observatory under programme focus ID 188.B- 3002. These data have been obtained from the GES Data Archive. This work has made use of data from the European Space Agency (ESA) mission Gaia. We acknowledge financial support from the Universidad Complutense de Madrid (UCM) and by the Spanish Ministerio de Ciencia, Innovaci\u00f3n y Universidades, Ministerio de Econom\u00eda y Competitividad, from project AYA2016-79425-C3-1-P and PID2019-109522GB-C5[4]/AEI/10.13039/501100011033. Dependence with rotation, activity and metallicity. Li-age relation Candidate members for each cluster are selected from the Gaia-ESO Survey (GES) (Gilmore et al. 2012) iDR6 data based on the following criteria: RVs, Gaia astrometry (proper motions and parallaxes), gravity indicators - Kiel (logg vs Teff) and \ud835\udefe index diagrams -, [Fe/H] metallicity, and the position in the EW(Li) vs Teff diagram. As an example we show here the case of IC 2602 (PMs, CMD, EW(Li) vs Teff and \ud835\udefe index) and NGC 6705 (RV, Kiel diagram and [Fe/H] histogram): Selection criteria and cluster membership Abstract EW(Li) vs Teff: Plotting the lithium envelopes of IC 2602 (35 Myr), the Pleiades (78-125 Myr), and the Hyades (750 Myr) in a EW(Li) vs Teff figure, we can estimate age ranges and verify probable members (see Montes et al. 2001). Kinematic selection: We studied the RV distribution of each cluster by applying a 2-sigma clipping procedure and adopting a 2\u03c3 limit about the cluster mean yielded by the Gaussian fit to identify the most likely RV members. The Kiel diagram enables us to discard giant outliers (logg < 3.5) \u2013 some of them Li-rich giants (A(Li) > 1.5) \u2013 and other field contaminants. We used the PARSEC isochrones (Bressan et al. 2012), with Z = 0.019 and ages ranging from 1 Myr to 7 Gyr. For young clusters, we used the gravity indicator gamma (see \u03b3 index vs Teff diagram above) to discard giant contaminants before applying any kinematic and astrometric criteria. XI Reuni\u00f3n Cient\u00edfica de la SEA 5-9 September 2022, La Laguna [Fe/H] histograms also help rule out stars with metallicities too far away from the mean for each cluster. M.L. Guti\u00e9rrez Albarr\u00e1n1, D. Montes1 , H.M. Tabernero1,2, J.I. Gonz\u00e1lez Hern\u00e1ndez3,4, A. Frasca5, A.C. Lanzafame5, R. Smiljanic6, A.J. Korn7, S. Randich8, G. Gilmore9, et al. & GES Survey Builders In this work we used a series of open clusters and associations observed by the Gaia-ESO Survey (GES) to study the use of lithium abundances (Li I spectral line at 6708 \u00c5) as an age indicator for pre- and main-sequence FGKM late-type stars. Previous studies of open clusters have shown that lithium depletion is not only strongly age dependent, but also shows a complex pattern with several other parameters, such as rotation, chromospheric activity and metallicity. Using the available data from both GES iDR6 and Gaia EDR3, we performed a thorough membership analysis and obtained lists of candidate members for 42 open clusters, ranging in age from 1-3 Myr to 4.5 Gyr. We then conducted a comparative study that allowed us to quantify the observable lithium dispersion in each cluster and study the influence of rotation, activity and metallicity in the lithium dispersion of the selected candidates. All this allowed us to calibrate a Li-age relation and create empirical lithium envelopes for 27 of of the 42 sample clusters, also constraining the LDB for those clusters in the 15-600 Myr age range. We used the rotational velocities (vsini), chromospheric activity indicators (EW(H\u03b1)) and [Fe/H] metallicities provided by GES iDR6, as well as additional rotational periods (Prot) from the literature, including Kepler, K2 and TESS measurements. We confirmed the findings of former publications and observed that members with higher values of EW(Li) tend to be faster rotators a", "label": "poster"}
{"text": "TEMPLATE DESIGN \u00a9 2008 www.PosterPresentations.com \u2022 There were 3 cropping rotations in place at St. John: winter pea-winter wheat-spring wheat, cover crop- winter wheat-spring wheat, and fallow-winter wheat- spring wheat. These rotations were replicated so that every crop in each rotation was present in the field. This design was replicated 5 times in the same field. \u2022 Crops: winter wheat, spring wheat, winter pea, multi- species cover crop, and a fallow plot. \u2022 Sentinel seed station design: medium-sized Petri dish bottoms, filled with plasticine modeling clay with 20 seeds of each species pressed into the clay. \u2022 Closed treatment had 0.64 cm hardware mesh cage to exclude rodents and birds. Open treatment had no cage. \u2022 There were 4 sampling dates between July 5-Sep 26 2019 and the stations were left in the field for 7 days. \u2022 There were 20 replications of fallow, winter pea, and cover crop plots and 60 replications of winter wheat and spring wheat (n = 180). Seed Removal in Pacific Northwest Cereal Production Systems Jessica Kalin*, Sanford D. Eigenbrode* *Department of Entomology, Plant Pathology, and Nematology University of Idaho Introduction Methods Acknowledgements Research Objective: Test these four hypotheses using sentinel seed baits deployed into the replicated trial at St. John, WA. Results References \u2022 With projected changes in climate, Pacific Northwest growers are expected to modify their existing cereal- based cropping systems to more resilient, diversified systems. \u2022 Diversified systems include more crops, crop rotations, and cover cropping. \u2022 These cropping system modifications potentially increase vulnerability to weed and insect pests and this requires research. \u2022 Bromus tectorum (downy brome), Chenopodium album (common lambsquarters), and Anthemis cotula (Mayweed chamomile) are common weeds in the Pacific Northwest. [1-3] \u2022 \u201cLandscapes in Transition\u201d (LIT) is an inter-disciplinary, multi-institutional Coordinated Agricultural Project focuse on the development and adoption of sustainable and resilient cereal-based production systems in the Inland Pacific Northwest. \u2022 As part of LIT, we compared the removal rates by seed predators of these 3 weed species in 5 different crops in an ongoing replicated trial in St. John, WA. Plots at the field site in St. John, Washington. Seed trays placed ~1m apart. This study is part of a large collaborative project, Landscapes in Transition, funded through award #2017-68002-26819 from the National Institute of Food and Agriculture. Special thanks to Grace Overlie and Anna Stutz. Table 1. Partial ANOVA table with weed species, date, crop, treatment, and their interactions. Significant effects listed left. Highlighted effects are reported in detail here. Non-significant effects include: cage, weed species:cage, weed species:date:cage, and weed species:date:cage:crop. [1] Rydrych, D.J. 1974. Competition between winter wheat and downy brome. Weed Science, 22(3): 211-214. [2] Lyon, D.J., Burke, I.C., Hulting, A.G. & Campbell, J.M. 2017. Integrated management of mayweed chamomile in wheat and pulse crop production systems. Washington State University Extension Publications PNW695, pp 106. [3] Bohan, D.A., Boursault, A., Brooks, D.R., & Petit, S. 2011. National-scale regulation of the weed seedbank by carabid predators. Journal of Applied Ecology, 48: 888-898. **All photographs taken by Jessica Kalin unless stated otherwise. \u2022 The effects of weed species and crop were significant. The interaction between these effects (p < 0.01) is due to the low rates of lambsquarters seed removal compared to Mayweed and downy brome, especially in fallow. \u2022 Removal rates did not differ between open and closed stations (\u201ccage\u201d effect); the cage x crop interaction (p < 0.001) reflects the higher removal rates from caged stations in fallow and cover crop plots than in other crops. This was most evident on week 2 (wk2), accounting for the three-way interaction including date. \u2022 Removal of lambsquarte", "label": "poster"}
{"text": "We also studied analogous ensembles of hard spinners driven to rotate in opposite directions by an applied torque. The dynamics of the spinners are governed by the Langevin equation. Simulations were performed for 16,384 spinners. References 3. Coarsening dynamics of binary liquids with active rotation2 Bio-inspired colloidal machine: bringing colloids to life S. Sabrina1, A. Brooks1, M. Spellings2,3, S. C. Glotzer2,3,4 and K. J. M. Bishop1 1Department of Chemical Engineering, The Pennsylvania State University, University Park, PA \u2013 16802. 2Department of Chemical Engineering, 3Biointerfaces Institute and 4Department of Material Science and Engineering, University of Michigan, Ann Arbor, MI \u2013 48109. 1. Motivation This work was supported as part of the Center for Bio-Inspired Energy Science (CBES), an Energy Frontier Research Center (EFRC) funded by the U.S. Department of Energy (DOE), Office of Science, Basic Energy Sciences under Award # DE- SC0000989. 4. Comparison with microscopic model2 Funding and Affiliations Acknowledgements 5. Current work: shape-directed actuation of spinners The governing equations were solved numerically on a square domain (\ud835\udc3f\u00d7 \ud835\udc3f) with periodic boundaries using semi-implicit (Adams-Bashforth) Fourier spectral method. The continuum model suggests that activity-induced flows influence the coarsening dynamics depending on the strength of rotation (\ud835\udefc) and strength of frictional damping (\ud835\udefd). Spinners \u2013 converting energy into rotational motion \u2013 phase separate via diffusion under strong frictional damping1. 1. Diffusion-controlled passive coarsening is observed for any strength of active rotation under conditions of strong frictional damping (\ud835\udefd\u226b1). 2. Accelerated active coarsening is observed under conditions of weak rotation (\ud835\udefc\u226a1) and weak frictional damping (\ud835\udefd\u226a1). 3. Multi-scale structures emerge under conditions of weak rotation(\ud835\udefc\u226a1) and zero frictional damping (\ud835\udefd= 0). 4. Vortex-doublets emerge under conditions of strong rotation (\ud835\udefc\u226b1) and zero frictional damping (\ud835\udefd= 0). Vortex-doublet stronger rotation less friction stronger rotation stronger rotation Compositional field Velocity field Domain size 2. Background and continuum model2 spinners \ud835\udc45~ \ud835\udc611/3 phase separated fluid Assumptions 1. Incompressible, Newtonian fluid 2. Bulk properties (e.g., density \u03c1, viscosity \ud835\udf02) same in both phases 3. Low Reynolds number 4. Neglect Capillary forces Strength of rotation, \ud835\udefc= \ud835\udf0f\u0424\ud835\udc47\ud835\udf02 Strength of friction, \ud835\udefd= \ud835\udc4f\ud835\udc3f2 \ud835\udf02 Here,\ud835\udf0fis driving torque, \u0424 is equilibrium composition, \ud835\udc47is time of diffusive unmixing over \ud835\udc3f, \ud835\udc3fis interfacial thickness, and \ud835\udc4fis friction coefficient. 1. Nguyen et. al., Physical Review Letter (2014) 2. Sabrina et. al., (submitted 2015) 3. Squires and Bazant, Journal of Fluid Mechanics (2006) 4. Gangwal et. al., Physical Review Letter (2008) 5. Yan et. al., Optical Materials Express (2011). Capture & Convert Move & Transport Sense & Respond Reconfigure & Adapt Heal & Repair Grow & Replicate \u2018Life-like\u2019 synthetic materials from colloids Distributed Centralized Vs. Energy conversion into motion Features of distributed actuation \u2022 Robust to failure(e.g., muscles) \u2022 Intelligent and adaptive behavior(e.g., bacterial swarms) \ud835\udefd= 102 \ud835\udefc= 10\u22122 \ud835\udefd= 0 \ud835\udefd=0 \ud835\udc61= 105 \ud835\udc61= 105 \ud835\udc61= 105 \ud835\udc61= 104 \ud835\udc61= 104 \ud835\udefc\u2032 = 0.25 \ud835\udc61= 105 \ud835\udefd\u2032 = 10\u22122 \ud835\udefd\u2032 = 1 \ud835\udefc\u2032 = 0.25 Passive Active R i i i i d m dt \uf067 \uf03d \uf02d \uf02b v F v F (a) Synthesis of different shapes of spinners by photolithography. (b) Selective electroless Ag plating of spinners5 (c) Experimental setup of ICEP-driven spinners. Continuity Convective Cahn-Hilliard Navier-Stokes active driving force frictional damping Induced-charged electro-osmotic flow (ICEO) in ac electric field can actuate particles using their shape asymmetry and surface heterogeneity3. We are synthesizing spinners of complex shape actuated by external fields such as electric and acoustic fields. The design of ICEP-driven spinners of complex shapes is guided by COMSOL simulations. Induced- charge electrophoresis (ICEP)4 Angular velocity of di", "label": "poster"}
{"text": "Ophiuchus star-forming region (d ~ 135 pc) 12 Class I sources Herschel colour map Angular resolution: 0.4\u201d (~50 AU) Continuum: 0.87 mm Molecular lines Disk tracers: C17O, H13CO+, C34S Warm chemistry: CH3OH Shock tracer: SO2 ALMA Observations The formation of low-mass stars involves physical and chemical processes that affect the evolution of the disk and set the initial chemical conditions for planet formation [1,2]. However, the physical processes on small disk scales (< 500 AU) are still not well understood [3,4]. How is the envelope material incorporated into the disk? Which physical and chemical processes dominate on disk scales? References: [1] J\u00f8rgensen, J. et al., 2008, ApJ, 683, 822; [2] Bergin, E. & Cleeves, I., 2018, haex.bookE, 137B.; [3] J\u00f8rgensen J. et al. 2009, A&A, 507, 861; [4] Yen H.-W. et al. 2015, ApJ, 799, 193; [5] Artur de la Villarmois, E. et al. 2019, A&A, 626, 71; [6] Kenyon, S. J. & Hartmann, L. 1995, ApJS, 101, 117. 100 200 300 400 0 3 6 9 12 15 18 21 Tbol [K] Lbol [L\u2299] Class I/II Class I Class 0 Decreasing C17O and C18O Colder SO2 No lines on-source C17O SO2 Mass evolution Linear correlation between luminosity and protostellar mass gives \u1e40acc = 2.4 \u00b1 0.6 \u2a2f 10-7 M\u2299 yr-1 for Class I sources [5]. A constant \u1e40acc cannot explain the observed luminosities and protostellar ages \u2192 Episodic accretion bursts: accretion rate varies with time and the protostar gains a significant amount of material in a short period of time [6]. Chemical evolution Chemical differentiation between C17O and SO2. C17O traces high gas column densities and is detected towards the youngest sources. Warm, compact, and high velocity SO2 emission is related with high luminosities and, therefore, high \u1e40acc. \u02d9Macc = LbolR\u22c6 GM\u22c6 Results - A typical protostar will spend most of its lifetime in a quiescent state of accretion. - SO2 may be tracing accretion socks in the envelope-disk interface and highlighting sources with high accretion rates. The formation of disks results in characteristic chemical imprints. Introduction Conclusions The physical and chemical fingerprint of planet-forming disks Elizabeth Artur de la Villarmois* (elizabeth.artur@nbi.ku.dk), Jes J\u00f8rgensen, Lars Kristensen, Ted Bergin, Daniel Harsono, Nami Sakai, Ewine van Dishoeck & Satoshi Yamamoto *Niels Bohr Institute & Centre for Star and Planet Formation - University of Copenhagen 0.5 pc", "label": "poster"}
{"text": "Mercury Target Neutrinos 24m Baseline Iron Shielding Proton Beam \u03c0+ \u03bc+\u03bd\u03bc \u03bc+ e+\u03bd\u03bc \u03bde K+ \u03bc+\u03bd\u03bc 17 Tons GdLS 30 Tons LS Veto IBD \u03bde+p \u2192 e++n n+Gd \u2192 Gd+\u03b3 Prompt Delayed,\ud835\udf0f\u224828\u03bcs 96 inward looking 24 outward looking 120 10-inch PMTS J A N U S J A N U S J A N U S J A N U S J A N U S F O N T U S Large PMT Pulse Single PE PMT Pulse Custom Analog Proto-board TI ADS54J66 ADC Eval Board Analog & ADC Proto-board Xilinx Kintex Ultrascale Dev Board JANUS PCB design is complete JANUS : 32 Channel DAQ Board ... ... ATCA Backplane Global Bus PMT Data (Ethernet) Energy Sum (Serial 10Gbps) SFP+ Global Trigger Energy Sum (Serial 10Gbps) SFP+ PMT Data (Ethernet) Process Data and Triggers Digital (Serial) FPGA 1 Xilinx Kintex Ultrascale JESD204B FPGA 0 Xilinx Kintex Ultrascale 32 PMT Channels Analog Differential Signals Condition the PMT Signals Digitize the Waveforms ADC 7 500 MHz, 14-bit ADC 0 500 MHz, 14-bit ADC 3 500 MHz, 14-bit Frontend Analog Transceiver Transceiver Global Clock ADC 4 500 MHz, 14-bit FONTUS : Trigger Board FPGA Xilinx Kintex Ultrascale ATCA Backplane Energy Sum (Serial 10Gbps) Clock Front Panel Beam Signal External Triggers Global Trigger Global Bus Trigger Info (Ethernet) J A N U S J A N U S J A N U S J A N U S J A N U S F O N T U S 104 105 106 107 Neutrino Flux (Arb.) \u00b5 \u03c0 K -600 -400 -200 0 200 400 600 800 1000 Time (ns) 0 20 Current (A) \u00d725Hz Beam Pulses Process Trigger Data to Produce Triggers Proto-board that can emulate both JANUS & FONTUS functionality is being produced. Pending testing and production of the final JANUS & FONTUS PCBs commissioning of the DAQ will begin Fall 2020. Once this design has been sucessfully deployed for JSNS2 we hope to demonstrate this as a \"one size fits all\" DAQ solution for medium- scale liquid scintillator detectors. The 14-bit resolution & large dynamic range provides sensitivity to high energy neutrinos, e.g. KDAR neutrinos, without losing single- PE sensitivity. The upgrade DAQ will be hosted within an ATCA shelf with 5 DAQ boards (JANUS) and one trigger board (FONTUS). Design can be expanded to fit possible future needs. Tests of the analog circuitry have demonstrated its ability to produce a differential copy of the input with excellent signal integrity. The FPGA based trigger allows event selection based on known event timing relations and the flexibility to design trigger logic specific to the physics of interest. Expected data readout rate is 1 Gbps per FPGA. The electronics will need to trigger based upon timing signals from the beam facility as well as event energy and timing conditions. Our system will leverage modern FPGA and telecom electronics to meet these requirements. The J-PARC Sterile Neutrino Search at the J-PARC Spallation Neutron Source (JSNS2) began taking data with DAQ electronics donated by the Double Chooz experiment. The Double Chooz electronics, however, were not designed for a beam based experiment and are not sensitive across the entire energy range of interest for JSNS2. I have been working, as part of a team, to develop upgrade electronics that will be better suited to JSNS2's energy and timing requirements. The upgrade electronics will enhance our physics capabilities by providing a excellent efficiency and resolution over a large energy range. Firmware testing and development underway using commercial and custom bench-top electronics. Beam Neutrino Production: Spectrum & Timing JSNS2 Detector & Primary Physics Interactions The Benefit of 14-bit Resolution The Design and Development of the JSNS2 DAQ Upgrade Eric Marzec (marzece@umich.edu) For the JSNS2 Collaboration JSNS2 Design Development", "label": "poster"}
{"text": "Fabrication of Lightweight Aluminium Metal matrix composites and validation In Green Vehicles FLAMINGo is a H2020 project funded under the LC-GV-06-2020 topic, aiming to the development of high-performance lightweight Aluminum composite materials thanks to a novel metallurgical and forming combined approach for making automotive parts. The FLAMINGo Project aims to manufacture strengthened Aluminium Metal Matrix nano-Composites, Al-MMnC, with enhanced properties in terms of strength and stiffness, compared to the existed Al alloys used in Green Vehicles. Nanoparticles & AI masterbatches Topology Optimisation Foundry Primary & Secondary Aluminium LCA/LCCA SAFETY LPDC, HPDC, GSC, DC Extrusion FieldTest Recycling WEIGHT SAVING REDESIGN LIGHTER ENGINE SMALLER BATTERY PACK THE PARTNERS THIS PROJECT HAS RECEIVED FUNDING FROM THE EUROPEAN UNION\u2019S H2020 PROGRAMME UNDER THE GRANT AGREEMENT NO. 101007011 @FLAMINGoProjectH2020 @FLAMINGoPH2020 @FLAMINGo Project H2020 info@flamingo-project.eu www.flamingo-project.eu CONNECT WITH US", "label": "poster"}
{"text": "Objective TERMINUS addresses the challenge of unlocking the recycling and reuse of flexible multi-layer and multi- compound packaging through the design of new formulations with smart enzyme-containing adhesive or tie layer polymers. After a specific trigger, the enzyme will start degrading the polyurethane-based adhesive (PUR) or tie layer (TL), thus enabling the delamination of the different layers of packaging, which can then be recycled. Multilayers packaging recycling: the Terminus strategy TERMINUS has received funding from the European Union\u2019s Horizon 2020 research and innovation programme, under grant agreement number 814400. This presentation refects only the views of the authors. European commission and Research Executive Agency are not responsible for any use that may be made of the information it contains. A. Romano, G. Totaro, A. Celli, C. Gioia, N. Raddadi, G. Zanaroli, L. Sisti Dept. of Civil, Chemical, Environmental and Materials Engineering, Alma Mater Studiorum Background Multi-layer packaging films are largelyexploited in the food industry, because they extend the lifetime of goods, helping to reduce food waste, but due the multi-material structure, these material are unrecyclable and currently 100% of multi-layer packaging is incinerated or landfilled, only for beverage cartons recyclability is demonstrated in practice and at scale. in-built Triggered Enzymes to Recycle Multi-layers: an Innovation for Uses in plastic-packaging SELECTION IMMOBILIZATION and TRIGGERING INCORPORATION Strategy of the hybrid systems into the adhesives of enzymes of the most active enzymes for adhesives 15% improvement in economic efficiency of end-of-life management 80% reduction of landfilling for multi-layer plastic packaging 55% reduction of overall plastic landfilling 65% decrease in the overall CO\u2082 footprint Expected Results", "label": "poster"}
{"text": "This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement number 824603. @ACTION4CS #ACTION4CS https://actionproject.eu Participant motivation to engage in a citizen science campaign: the case of the TESS network Gloria Re Calegari (Cefriel - gloria.re@cefriel.com), Irene Celino (Cefriel - irene.celino@cefriel.com), Mario Scrocca (Cefriel - mario.scrocca@cefriel.com), Jaime Zamorano (UCM - jzamorano@fis.ucm.es), Esteban Gonz\u00e1lez Guardia (UPM - egonzalez@fi.upm.es) The contents of the poster reflects the author\u2019s views. The European Commission is not liable for any use that may be made of the information contained therein. Survey design \u2022 define the research question \u2022 define investigated factors \u2022 formulate questions \u2022 set-up the questionnaire \u2022 test the survey with some user Survey administration \u2022 identify list of respondents \u2022 send survey \u2022 re-solicit responses, if necessary Collect & Process survey responses \u2022 monitor answer collection \u2022 export data \u2022 process data Interpret & Share survey results \u2022 draw insights from result analysis \u2022 anonymizing data if needed \u2022 select suitable open licenses \u2022 openly publish research results (e.g. as research objects) Research question Collect & Process survey results Survey administration Link of the survey sent by email to 120 people hosting photometers. One reminder after a week from the initial sending. 83/120 volunteers answered the survey (69%) 2 Survey design Selection of investigated factors \u2022 Reference methodology inspired by the Schwartz Theory of Basic Values1 \u2022 10 motivating factors related to instinsic motivation that may influence CS global motivation (self-direction, stimulation, hedonism, achievement, power, conformity, benevolence, universalism, routine and belongingness) Questions formulation \u2022 2 closed questions for each motivating factor (answers values from 1 to 5) \u2022 1 closed question for global motivation (answers values from 1 to 5) \u2022 1 open question for free text motivation \u2022 10 questions for demographics and data usage Total: 32 questions TESS network initiative aims to collect sky brightness measurements through sensors to fight light pollution Telescope Encoder and Sky Sensor (TESS-W) photometer is a compact and inexpensive device developed under STARS4ALL project by the Universidad Complutense de Madrid As of today, 200+ TESS photometer hosted by 120 people in Asia, Africa, North and South America, Europe and Australia (sensors displayed on this map https://tess.dashboards.stars4all.eu/) Citizen Scientists mainly involved in data collection task. No monetary rewards for participants. Interpret & Share survey results The survey structure, the collected answers and the analysis of correlation are openly available in RDF and CSV formats on Zenodo https://zenodo.org/record/3739058#.XxcK1udS9PY. Reproducibility and Open Science. This survey can be reused to study motivation in other CS communities. Contact us to have support on this! The TESS Network community Demographic In your own word, which is the main motivation why you decided to host a photometer? How much are you motivated in participating to the TESS Network? Global motivation Motivating factors 85% are male, 70% of volunteers are older than 45 years old Which of the following categories identifies you the most? What are you using (or planning to use) the data provided by your photometer for? 75% interested in downloading, exploring or using data collected from all the sensors installed, but only 30% has evidence about data usage by researchers. Learning about the project discoveries has in itself been framed as a reward. Increasing the sharing of the results can be an added value for the community. Factor Mean Answers Correlation with global motivation Questions Self-direction 4,43 0.491*** want to learn interested in topics Benevolence 4,42 0.62*** good thing to do contribute and help the scientific research Universalism 4,33 0.672***", "label": "poster"}
{"text": "IPM strategies against Drosophila suzukii (IPMDROS) Funding Non-competitive funding mechanism. Each funder only pays for the participation of their own national researchers. Total funding \u20ac 130,000 Picture 1 Picture 1 Picture 1 Goals The goal of the project is to participate to the development of IPM programs for the control of D. suzukii , that are of great importance to reduce the huge economic impact that this fly can potentially exert on European agriculture Research consortium ES-INIA; TR-GDAR, AT-AGES; IT-CRA; BE- ILVO Contact information Project coordinator: Ismael S\u00e1nchez Ramos ismael@inia.es Key outputs and results The expected results of the project are: \u2022 A temperature based model including parameters such as mortality of immature stages, developmental rate of immature stages, reproduction, longevity of adults, life table parameters for the prediction of risk situations, possible new areas of colonization and number of generations per season to be implemented in an IPM approach for the control of D. suzukii. \u2022 A basic data survey about the cold tolerance and overwintering strategies of European populations of D. suzukii to determine which European countries are at risk of D. suzukii establishment. \u2022 Improved reliable and easy to handle trapping devices for monitoring and population reduction of D. suzukii. \u2022 Evaluated selective insecticides with different mode of action (e.g. IGRs) and alternative plant protection products including entomopathogenic microorganisms for the control of D. suzukii to increase the available alternative control methods for IPM programs. \u2022 Surveys and protocols for early detection of D. suzukii in non-invaded countries. Objectives Objectives are \u2022To improve of basic knowledge about the biology of the fly, including overwintering behaviour and effect of temperature on development, reproduction and population increase. \u2022To develop of effective trapping systems for population reduction \u2022To evaluate alternative methods for control, such as insect growth regulators and entomopathogenic microorganisms. \u2022To monitor surveys for early detection and development of quarantine measures and effective surveys of goods in global trade among countries 07/2014-12/2016", "label": "poster"}
{"text": "Zielgruppe Wir schaffen eine bedarfsgerechte Infra- struktur f\u00fcr die Forschungsdaten unserer Communities von der Architektur-, Kunst- und Musik- bis hin zu Theater-, Tanz-, Film- und Medienwissenschaft. Struktur Dienste Ressourcen Helpdesk KONSORTIUM F\u00dcR FORSCHUNGSDATEN ZU MATERIELLEN UND IMMATERIELLEN KULTURG\u00dcTERN NFDI4Culture strukturiert sein Arbeitspro- gramm entlang des Forschungsdatenlebens- zyklus in sechs operative Aufgabenbereiche. Ein siebter umfasst alle Prozesse, die Administration und Kommunikation. Unser \u00fcbergeordnetes Ziel sind die Registrierung und die Verbesserung bestehender Dienste sowie die Entwicklung neuer Dienste f\u00fcr das Forschungs- datenmanagement. In unserer Knowlege Base stellen wir Handreichungen zur Verf\u00fcgung, kuratierte Findmittel, Berichte, Videotutorials und daneben auch technische Schnittstellen zu Forschungsdaten. Der NFDI4Culture Helpdesk ber\u00e4t zu allen Fragen rund um das Management von Forschungsdaten in allen Phasen des Daten- lebenszyklus. Spokesperson und Hosting Institution 55131 Mainz Prof. Torsten Schrade Akademie der Wissenschaften und der Literatur | Mainz Geschwister-Scholl-Str. 2 Kontakt Mastodon: https://nfdi.social/@nfdi4culture https://nfdi4culture.de contact@nfdi4culture.de Abb. v.o.: Mittelalterliche Glasmalerei: J\u00fcngstes Gericht, Weltgerichtsfenster im Dom Eichst\u00e4tt, Andrea G\u00f6ssel, CC BY-NC 4.0; Illustration des NFDI4Culture Arbeitsprogrammes, Sarah Pittroff, CC BY 4.0; Business boy with rocket, A.J. Rich; AI Human Brain Processor Circuit, 13FTStudio; Vintage styled rotary phone with help sign on a white background, Doomu.", "label": "poster"}
{"text": "The Impact of Living with Spinal Muscular Atrophy in Malaysia from Patients\u2019 and Caregivers\u2019 Perspectives. Karina Koh1 , Azlina Ahmad Annuar2, Fahisham Taib3, Koh Cha Ling4, Edmund Lim Soon Chin5 , Ch\u2019ng Gaik Siew6 1Clinical Research Centre, Hospital Kuala Lumpur, 2Department of Biomedical Science, Faculty of Medicine, University of Malaya, 3Department of Paediatrics, Hospital Universiti Sains Malaysia, 4HELP University, Kuala Lumpur, 5Persatuan Kebajikan Ceriajaya Kuala Lumpur Dan Selangor (WeCareJourney), 6 Genetics Department, Hospital Pulau Pinang. NMRR-18-3248-42367 Introduction: Spinal Muscular Atrophy (SMA) is a recessively inherited neuromuscular disorder caused by deletions or mutations in the survival motor neuron 1 gene (SMN1). Estimated incidence rate in Malaysia is 1 in 20,000 population with 25-50 babies born annually.\u00b9 The clinical type of SMA is defined by the age of onset and severity of the disease, from type 0 to type 4. 2 Currently, there is no cure for SMA, but disease modifying therapies can delay disease progression. There is a lack of knowledge on SMA amongst the public and even healthcare providers, which may impact the perception of the disease and its proper management. This study aims to explore the impact of SMA on the lives and daily activities of SMA patients and their caregivers. Methods: This was a mixed method cross-sectional study consisting of; Conclusion: This study, to the best of our knowledge represents the first comprehensive study on SMA in South East Asia, highlights a plethora of issues and challenges experienced by PWSMA and their caregivers in Malaysia, from the point of SMA diagnosis and throughout the management of care, in addition to the deep psychosocial impact of living with SMA. Their voices will help to inform stakeholders of areas of improvement needed in clinical practice, the education system and the society at large. Results: A total of 42 individuals participated in the quantitative survey, of whom 13 were persons with spinal muscular atrophy (PWSMA) and 29 were caregivers. After completing the survey, 7 PWSMA and 23 caregivers proceeded with the interview sessions. Table 1 summarizes the sociodemographic and characteristics of the participants. The impact of living with SMA are as shown in Table 2. The findings from the FGD and IDIs are summarized in Table 3. Characteristics PWSMA N = 13(%) Caregivers of PWSMA N = 29(%) Gender Male Female 5(38) 8(62) 11(38) 18(62) Ethnicity Malay Chinese Indian Others 7 (54) 5 (38) 1 (8) 0 22 (76) 5(17) 1 (3) 1 (3) Age (years) 10-19 20-29 30-39 40-49 50 and above 2 (14) 9 (69) 1 (8) 1 (8) 0 - 2 (7) 10 (34) 9 (31) 8 (28) SMA Type Type 1 Type 2 Type 3 0 (0) 9 (69) 4 (31) 8 (28) 11 (38) 10 (34) Table 1: Characteristic of participants Table 2: Impact of living with SMA Physical & psychosocial impact of SMA PWSMA N = 13 (%) Caregivers of PWSMA N = 29 (%) Feel stressed 7 (54) 16 (55) Feel depressed 5 (38) 6 (21) Feel anxious 5 (38) 22 (76) Feel socially isolated 4 (31) 3 (10) Unable to self transfer 7 (54) 17 (59) Unable to turn in bed 5 (38) 11 (38) Unable to manage personal hygiene 4 (31) 15 (52) Unable to attend work/school 4 (31) 8 (28) Limited social activities 4 (31) 6 (21) Unable to feed oneself 3 (23) 5 (17) Discussion: This study has initiated an important step in raising the voices of PWSMA and their families, by highlighting a number of issues and their unmet needs. The journey from diagnosis to managing their daily lives is fraught with frustrations and anxiety similar to the findings of Qian et al. \u2074 The psychosocial impact of SMA also echoes a study conducted in Denmark where all the adult PWSMA lived with anxiety and fear of progressive motor decline.5 Moving forward, there is a need for a multidisciplinary team to provide a holistic care from diagnosis to treatment, rehabilitation, and psychosocial support. Transdisciplinary collaboration and open communication between all the stakeholders of various specialties focusing on ", "label": "poster"}
{"text": "SSHOC social sciences & humanities open cloud \u201cSocial Sciences and Humanities Open Cloud\u201d, has received funding from the European Union\u2019s Horizon 2020 project call H2020-INFRAEOSC-04-2018, grant agreement #823782 How does this thematic SSH Marketplace connect to the EOSC? How will the Marketplace advance SSH and cross-disciplinary research? SSHOC social sciences & humanities open cloud A Marketplace for the Social Sciences and Humanities 1. Contextualised solutions Through a process-oriented approach, centred around the research workflows, the SSHOC Marketplace contextualises interrelated datasets, tools, and services with tutorials, links to training material, user stories, showcases, and other relevant information. Interoperability will be achieved via the Data and Metadata Interoperability Hub being developed within SSHOC. Input For: 2. Modelling the EOSC Federating Core SSHOC Marketplace aims to make use of EOSC Federating Core, especially the Federated Identity (AAI) services and the Helpdesk. Views on common themes will also be exchanged and harmonised with other European and international organizations operating in the EOSC. Specific attention will be paid to the OpenAire initiative and its catalogues. Input For: 3. Bridging EOSC and the SSH community Like EOSC itself, the SSHOC Marketplace is being created and shaped by and for the research communities. The participating research infrastructures have defined the state of the art and user requirements through multiple exchanges with the SSH community using Agile and User Centred Design approaches. Input For: Context Related materials such as code or data are linked, providing additional context Support Users have access to appropriate training materials for their use of tools Community With the inclusion of user feedback or ratings, the Marketplace is a \u201cStack Overflow\u201d for the SSH Gap analysis With all resources gathered in a central repository, it will be easier to identify tools that don\u2019t exist and should be developed to address specific needs Sustainability A focus on curation and information quality, and the creation of a sustainable governance model and user community ensure the durability of the Marketplace over time Serendipity Users find useful information they hadn\u2019t thought to look for! Join our Community K sshopencloud.eu t @SSHOpenCloud l /in/sshopencloud \u201c The SSHOC Marketplace is the only fully-integrated discovery portal which pools and harmonises the tools and services useful for the SSH research communities, offering a high quality and contextualised answer at every step of the research data life cycle. info@sshopencloud.eu \u2709 SSHOC Partners Read the System Specification for the SSH Open Marketplace Timeline January 2019 Launch of the SSHOC project June 2020 1st release of the SSH Marketplace December 2020 2nd Release of the SSH Marketplace December 2021 Final Release of the SSH Marketplace April 2022 End of the project", "label": "poster"}
{"text": "COAR - Confederation of Open Access Repositories: Reaching out to global interoperability through aligning repository networks Kathleen Shearer, COAR Executive Director, kathleen.shearer@coar-repositories.org Maxie Putlitz, COAR Office, office@coar-repositories.org Katharina M\u00fcller, COAR Office, office@coar-repositories.org COAR, the Confederation of Open Access Repositories, is a dynamic association of repository initiatives launched in October 2009, uniting roughly 100 members and partners from 35 countries from throughout Australia, Africa, Asia, Europe, Latin America, and North America. The association aims to enhance greater visibility and application of research outputs through global networks of Open Access digital repositories. Activities of COAR members and partners are undertaken in working and interest groups as well as task forces. Work areas range from repository content, global interoperability, over education and training to monitoring new trends and developments in the open access repository community. This poster will outline COAR\u2019s latest activities in order to inform the broader repository community and promote greater collaboration with others. COAR is an international organization based in Goettingen, Germany. The association acts as forum to learn about new trends; engage with international colleagues in the repository community; and ensure repositories adhere to global best practices and interoperability standards. COAR also actively promotes the role of repositories within the broader scholarly ecosystem and works with other actors to ensure alignment of services and infrastructure globally. Members and partners come together once a year in a general annual meeting to discuss important developments of the association and in the repository community. COAR has undertaken several activities over the last year to foster global repository interoperability through the initiative \u201cAligning Repository Networks\u201d. In this initiative several major international organizations joined together to underscore their support for immediate open access to research articles and aim for harmonized standards and common vocabularies. A petition has been set up which is still open for endorsements. Moreover in early February 2015 the Interoperability Working Group published the COAR Roadmap: Future Directions for Repository Interoperability. The roadmap identifies important trends and their associated action points for the repository community and will assist COAR in identifying priority areas for our interoperability", "label": "poster"}
{"text": "HIGH-THROUGHPUT YEAST SCREENING REVEALS A NEW DIMENSION OF INTRACELLULAR PATHOGENESIS. Malene L. Urbanus2, Harley O\u2019Connor Mount1, Eleanor A. Latomanski3, Dylan Valleau4, Frederick P. Roth1,5,6, Hayley J. Newton3, Alexei Savchenko4,7, Alexander W. Ensminger1,2 1. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; 2. Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada; 3. Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; 4. Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada; 5. Lunenfeld\u2010Tanenbaum Research Institute Mt. Sinai Hospital, Toronto, Ontario, Canada; 6. Donnelly Centre, University of Toronto, Toronto, Ontario, Canada; 7. Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada. WHAT IS A METAEFFECTOR? USING YEAST TO FIND THEM. WHAT\u2019S NEXT? Metaeffectors directly target other effectors HOST TARGET indirect Effectors target host proteins Legionella direct Effectors are proteins delivered to host cells via dedicated bacterial translocation machineries. The intracellular bacterial pathogen, Legionella pneumophila, uses a Type IV translocation system to deliver over 300 effectors to the eukaryotic host cell (~10% of its proteome). The canonical role of effectors is to modify host targets. Metaeffectors (or effectors of effectors) directly modify other translocated bacterial proteins rather than the host. Yin-Yang effectors behave like canonical effectors, but indirectly interact through counteracting modulation of a shared host target. 0 0.2 0.4 0.6 0.8 1 1.2 1.4 1.6 0 20 40 60 80 100 L. pneumophila infects a broad range of eukaryotic hosts (from protozoa to humans) and modulates conserved eukaryotic pathways. Because they target conserved pathways, 37% of L. pneumophila effectors cause a yeast growth defect of \u226520%) when heterologously expressed. Normalized spot sizes of effector-expressing yeast clones grown at 1,536 spot density. Yin-Yang effectors Query (MAT\u03b1, URA3) Array (MATa, HIS3) Diploid (MATa/\u03b1, HIS3, URA3) x sidD (lpg2465) sidM/drrA (lpg2464) query screen Induce expression. Image diploid spot size: ceg3 (lpg0080) 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 lpg0081 legA8/ankX (lpg0695) lem3 (lpg0696) 0 1000 2000 3000 4000 spot size (px), replicate 2 0 1000 2000 3000 4000 spot size (px), replicate 1 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 sdeB (lpg2156) sdjA* (lpg2508) sidJ (lpg2155) sdbB (lpg2482) sdbC (lpg2391) 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), array + query spot size (px), single IDTS lpg1148 legC3 (lpg1701) 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 ceg6/pkn5 (lpg0208) ravG (lpg0210) ravJ (lpg0944) legL1 (lpg0945) 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 legC7/ylfA lpg2298) mavE (lpg2344) 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 lem26 (lpg2523) mavL (lpg2526) 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 sidM/drrA (lpg2464) sidD (lpg2465) sidL/ceg14 (lpg0437) 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 legA11/ankJ (lpg0436) 0 1000 2000 3000 4000 0 1000 2000 3000 4000 spot size (px), replicate 2 spot size (px), replicate 1 sdeC (lpg2153) sdjA* (lpg2508) sidJ (lpg2155) 0 1000 2000 3000 4000 spot size (px), replicate 1 mavQ (lpg", "label": "poster"}
{"text": "Enabling the research centres of the future - the case of the Platform at the Interface of Science Plataforma de Interface \u00e0 Ci\u00eancia (Platform at the Interface of Science) - PIC is a bottom-up Portuguese informal network developed in 2016 by research managers and administrators (RMAs). This community reaches out around 770 RMAs. The added value of PIC in Portugal is based on: \u2022 connecting a broad range of professionals in different areas of specialization, such as science communication, data stewards, knowledge transfer valorization, including pre and post- award, \u2022 promoting their professionalization, and \u2022 working as a partner directly with policymakers and funders in research and development in proposing suggestions focused on the improvement of research systems. Improvement of research systems Community empowerment Broad range of profiles Exchange of best-practices Identification of bottlenecks Policy recommendations The importance of a strong Research Management system Greater awareness of R&I Policies Quality of the scientific production and translation of R&I results Informed decisions and efficient management Improved capacities within the R&I system to conduct open science Consolidation of European Research Area As a community of practice, PIC in the past has developed several initiatives to empower the community, including national events and online sessions of good practices sharing. Its work providing suggestions of improvements to science policy is done in a co-creation exercise with the inputs of the community, using social platforms. PIC organizes regular online meetings to discuss the latest topics on research management and organizes national events focused on the importance and centrality of research management and administration in the ecosystem. Major activities conducted include: - \u201cCaf\u00e9s Vamos falar de Gest\u00e3o de Ci\u00eancia\u201d - Annual events - Recommendations on new national legal frameworks and regulations in Research and Innovation (Lei da Ci\u00eancia, PL 51/2018; Regulamento do Emprego Cient\u00edfico da FCT) - Suggestions of improvement of specific funding regulations/initiatives Projetos de IC&DT em todos os Dom\u00ednios Cient\u00edficos 2017", "label": "poster"}
{"text": "Elements: Software Infrastructure for Programming and Architectural Exploration of Neuromorphic Computing Systems PI: Naga Kandasamy, Co-PI: Anup Das Award #: 2209745 Computing platforms currently used to run machine-learning tasks have high carbon footprint. Neuromorphic computing systems, which mimic biological neurons and synapses can implement these tasks in a highly energy-efficient fashion. Major challenges for neuromorphic computing lie in its adoption by users and from a system developer's perspective, to cope with faster time-to-market pressure for new neuromorphic chip designs. Our project develops a software infrastructure called NeuroXplorer, which allows for Spiking Neural Networks (SNNs) to be mapped onto neuromorphic hardware in the most efficient way possible. It provides: \u2022 Compiler backends to generate executable code for neuromorphic chips from a high-level specification of the machine-learning task. \u2022 Mapping and synthesis tools to execute machine-learning tasks on novel neuromorphic architectures built using FPGA. \u2022 High-performance software for hardware/software design-space exploration of new neuromorphic architectures. Project Motivation NeuroXplorer Infrastructure \u2022 Design optimization engine that can incorporate hardware design metrics such as energy, latency, throughput, and reliability, as well as SNN-oriented metrics such as ISI distortion and spike disorder. \u2022 System software stack that facilitates mapping of SNN-based applications to different neuromorphic platforms. \u2022 Cycle-accurate model of neuromorphic hardware utilizing a generalized template, which can be configured with hardware- and technology-specific details from manufacturers of neuromorphic systems. \u2022 Design-space exploration using data-flow models to represent machine- learning tasks executing on neuromorphic hardware which allows key performance metrics such as accuracy and power consumption cost to be estimated early during the design process. \u2022 Analysis of different technological alternatives for neuron and synapse circuits, and impact of scaling on neuromorphic hardware, facilitating optimization of key system-level design metrics. FPGAs can serve as accelerators for SNNs, for rapid prototyping, and as the deployment platform. QUANTISENC, a quantized spike-enabled neural core design software in Verilog, enables design and synthesis of SNNs on FPGAs. SONIC: Software-Designed Hardware Methodology SONIC (SOftware-defined NeuromorphIC) is an open-source software-defined hardware design methodology to make neuromorphic computing more accessible. Enables the user to define and train an SNN model using a high-level language such as Python, generate the corresponding register transfer level (RTL) description of the hardware, and create the hardware-software interface to improve programmability when the RTL is prototyped on FPGA and ASIC. \u2022 Neuromorphic hardware is configurable via software. \u2022 Modular System Verilog testbench to verify QUANTISENC for different learning tasks and datasets. \u2022 SONIC is available at github.com/drexel-DISCO/SONIC.git under the MIT license. Contact Information Naga Kandasamy kandasamy@drexel.edu Anup Das anup.das@drexel.edu QUANTISENC: Modular Neuromorphic Hardware Design We have started to integrate SONIC into existing courses to teach neuromorphic computing. \u2022 User specifies values for various hyperparameters in the SNN: number of layers, number of spiking neurons per layer, neuronal weights, and internal parameters of the neuron (resting membrane potential, threshold potential, and refractory period). \u2022 QUANTISENC allows setting separate quantization and precision policies for synaptic weights and internal state variables to co-optimize area, power, latency, and throughput to achieve a target performance. \u2022 Python script generates configuration file for design synthesis along with testbench to simulate/verify functionality of the FPGA design. \u2022 Available at github.com/drexel-DISCO/quantisenc-public.git under ", "label": "poster"}
{"text": "CMBI Introduction The FAIR (Findable, Accessible, Interoperable and Reusable) principles [1] were proposed to guide researchers to describe and share their data to increase data reuse and research reproducibility. Creating FAIR data can be challenging for multi-omics researchers due to a lack of tooling and a diverse landscape of (meta)data standards differing across -omics types. In X-omics [2], we develop a FAIR Data Cube [3] \u2013 a set of tools and services that help researchers in different stages of the Research Data Life Cycle including Creation and publish of multi-omics and metadata, Querying multi-omics studies, Analyzing access-protected data. The Implementation and Demonstration of the X-omics FAIR Data Cube XiaoFeng Liao1, Anna Niehues1,2, Martin Brandt3, Tom Ederveen1, Junda Huang1, Purva Kulkarni1,2, Casper de Visser1, Cenna Doornbos1, Joeri van der Velde4, Michael van Vliet5 and Peter-Bram \u2019t Hoen1 \u00b9Center for Molecular and Biomolecular Informatics, Radboud UMC, Nijmegen, The Netherlands, \u00b2Translational Metabolic Laboratory, Radboud UMC, Nijmegen, The Netherlands, \u00b3SURF, Amsterdam, The Netherlands, \u2074Genomics Coordination Center and Department of Genetics, University of Groningen and UMCG, The Netherlands, \u2075Division of Analytical Biosciences, Leiden Academic Centre for Drug Research, Leiden University, The Netherlands. Implementation & Demonstration The FAIR Data Cube is being developed in collaboration with the Trusted World of Corona (TWOC) [4] for demonstration. Contact XiaoFeng.Liao@radboudumc.nl Anna.Niehues@radboudumc.nl Peter-Bram.tHoen@radboudumc.nl Acknowledgements NWO, SURF, TWOC. The Netherlands X-omics Initiative is (partially) funded by the Dutch Research Council (NWO), project 184.034.019. no e e ra References: [1]. Wilkinson, M., Dumontier, M., Aalbersberg, I. et al. The FAIR Guiding Principles for scientific data management and stewardship. Sci Data 3, 160018 (2016). [7] https://github.com/Xomics/ISA-ACTION-Template [2]. www.x-omics.nl [8]. https://github.com/ISA-tools/isa-api [3]. https://github.com/Xomics/FAIRDataCube [9]. https://phenopacket-schema.readthedocs.io/en/latest/index.html [4]. https://www.health-holland.com/project/2020/trusted-world-of-corona [10]. https://github.com/Xomics/TWOCdemonstrator/tree/main/tools [5]. Su Y, Chen D, Yuan D, et al. Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19. Cell. 2020;183(6):1479-1495.e20. [11]. https://fdp.combi.umcn.nl [6]. Sansone, SA., Rocca-Serra, P., Field, D. et al. Toward interoperable bioscience data. Nat Genet 44, 121\u2013126 (2012). [12]. https://fdp.cmbi.umcn.nl/blazegraph/", "label": "poster"}
{"text": "1.Problem Statement and Objectives The introduction of DT and digital technologies in organisations has led to a growing trend of skills gap, hence more effective strategies for TD are needed. Objectives - Explore the strategies for TD and DT in the case organization. - Ascertain elements of Leadership and Culture connected to TD and DT - Establish what general theory and practice implications can be learned. 2. Context Heath services in Scotland. A case of NHS Education for Scotland (NES) Talent Development - Comprehensive, inclusive, personalized for individual employee; - Not limited to specific work-related interventions - Includes other development, training and learning. - Benefits both employees and organisations (Hedayati Mehdiabadi & Li, 2016; Rezaei & Beyerlein, 2018 ) Digital Transformation - We digitise information, - We digitalise processes and roles that make up the operations of a business - We digitally transform the business and its strategy (Bloomberg, 2018) 6. Methods 4. Influencing Factors Organisational culture: - Knowledge transfer is promoted - Effective communication between employees - Good rewards system Leadership behaviours: - More people-oriented than task-orientated - Leaders\u2019 concern for employees - Motivate and encourage staff 5. Conceptual map of Themes, Theory, Objectives, and Intended Contributions 3. Main Concepts - Exploratory - Case Study -Qualitative -Semi Structured Interviews References: 1.Bloomberg, J. (2018). Digitization, digitalization, and digital transformation: confuse them at your peril. Forbes. 2.Hedayati Mehdiabadi, A., & Li, J. (2016). Understanding Talent Development and Implications for Human Resource Development: 15(3), 263-294. https://doi.org/10.1177/1534484316655667 3. Rezaei, F., & Beyerlein, M. (2018). Talent development: a systematic literature review of empirical studies. 42(1/2), 75-90. https://doi.org/10.1108/EJTD-09-2017-0076 How can Talent Development be more effective during Digital Transformation? Stella Alhassan b00278519@studentmail.uws.ac.uk Director of Studies: Prof Stephen Gibb Supervisor: Dr Silvio Hofmann Download Poster", "label": "poster"}
{"text": "The insect vectors of Xylella fastidiosa (2) Funding Non-competitive funding mechanism. Each funder only pays for the participation of their own national researchers. Total funding \u20ac 127 000 Picture 1 Picture 1 Picture 1 Goals Philaenus spumarius plays an important role in the transmission of X. fastidiosa and understanding the biology and behaviour of vectors is vital in controlling the spread of the disease. The project aims to improve knowledge on vectors and potential vectors of X. fastidiosa within differing habitats and climates Research consortium SASA (GB), AGES(AT), ILVO (BE), MPI (NZ), INIAV (PT), NIB (SI), UCL (BE), ULB (BE), IVIA (ES), INRAT (TN) Contact information Project coordinator: Katherine Lester Katherine.lester@sasa.gov.scot Objectives The main objectives of the project are: \u2022To investigate the biology of vectors (and potential vectors) of X. fastidiosa, including feeding preferences and behaviour \u2022To perform transmission studies to determine the efficiency of vectors to transmit X. fastidiosa \u2022To study vector abundance and movement between crops and wild plants \u2022To Investigate traps or lures for collection of Philaenus spumarius \u2022To assess potential biocontrol agents for vectors such as parasites, fungi 03/2021-02/2023", "label": "poster"}
{"text": "I-RIM Conference 2019 October 18 - 20, Rome, Italy ISBN: 9788894580501 Experimental Robotic Systems for Design, Development and Testing of Orthopaedic Devices Nicola Sancisi Department of Industrial Engineering University of Bologna 40136 Bologna, Italy nicola.sancisi@unibo.it Michele Conconi Department of Industrial Engineering University of Bologna 40136 Bologna, Italy michele.conconi@unibo.it Vincenzo Parenti-Castelli Department of Industrial Engineering University of Bologna 40136 Bologna, Italy vincenzo.parenti@unibo.it Abstract\u2014The paper presents new robotic systems for test- ing general medical devices. Two applications are presented that show the advantage of experimental tests and articular models in prosthesis optimization and design. Keywords\u2014orthopaedic devices, prostheses, test, robotic rigs I. INTRODUCTION The main objective of orthopaedic devices such as articu- lar prostheses, prosthetic limbs, orthoses and exoskeletons is to replicate or recover the natural behaviour of a joint. This is obtained by a careful design of the mechanical constraints pro- vided by the device, imposing a wanted motion or behaviour of the limb including the device itself. For instance, articular prostheses aim at recovering the joint mobility and stability after substitution of the patient articular surfaces. Thus, pros- thetic components must replicate the natural joint behaviour, reproduce the function of articular structures removed during the implant, and respect the residual structures. To achieve these results, we believe that prosthesis design should be based on a rigorous process combining experi- mental analysis, joint modelling and prototype testing. Exper- imental motion analysis allow definition of the natural joint behaviour at different loading conditions, highlighting the role of each articular structure in constraining the joint motion [1]. Articular models replicate this role in a computational envi- ronment [1,2], where the articular constraints can be substi- tuted by mechanically equivalent counterparts that will con- stitute the basic features of the prosthesis (or the general de- vice). The result of the design process must be built and tested to verify if it satisfies the desired constraints [3,4]. Patient- specific features could be also introduced in the final solution, requiring personalised measures, design and production [4]. The first and the last step of this process consist in the ex- perimental analysis of the joint before and after implant. Be- fore proceeding with clinical studies on patients, these anal- yses can be performed by in-vitro tests on cadaveric speci- mens. Several in-vitro test rigs were proposed, which allow the study of the human joint dynamic behaviour. These de- vices can be divided into two groups: the human joint simula- tors, which aim at reproducing the behaviour of the joint in a physiological way [5], and the robot-based systems [6], which aim at reproducing the loading conditions at the joint by a ro- bot. The main objective of these rigs is to apply given dynamic external loads to the bones, without additional unwanted con- straints. Limitations of most devices currently in use are low flexion ranges, low dynamics and loads, reduced prescribed set of possible tests. The scope of this paper is to describe a family of new test- ing rigs that overcome the present limitations and that are cur- rently used for joint analyses by our group. Two examples and relevant results are included to show successful applications of a \u201ctesting and modelling\u201d approach to prosthesis design and optimization. II. TESTING RIGS A. General Feature The testing rigs were designed and built by our labs and show common characteristics. They feature three main parts (Fig. 1, left): a frame (4), a loading system (2, 3, and 11), and a portal (9). The loading system is a six degrees-of-freedom (dof) robot. A first version was a cable-driven robot using six pneumatic actuators, with an inherent force control. ", "label": "poster"}
{"text": "To boost the green transition, the availability of critical raw materials needs to be ensured. However, the battery sector has been experiencing increasing demand for raw materials for years and is vulnerable for supply risks. METALLICO will: \u2022 Recover valuable materials from primary and secondary resources \u2022 Demonstrate sustainable production and recovery of (critical) battery metals \u2022 Assess end-use of the recovered (critical) battery metals \u2022 Identify and characterize (critical) battery metals with innovative technologies \u2022 Enable social participation, stakeholder engagement and networking @METALLICO_EU @METALLICO Project * metallico@dechema.de https://metallico-project.eu The primary objective of METALLICO is to develop and validate sustainable and socially responsible recovery strategies for (critical) battery metals and their reuse. METALLICO will develop and optimize five innovative processes to recover the valuable materials needed in the battery industry and in other strategic sectors: Li, Co, Cu, Mn, Ni. METALLICO will demonstrate in four different case studies that the (critical) battery metals can be sustainable produced and recovered by upscaling the five METALLICO processes. Objective 5 Processes 4 Case Studies Demonstration of (critical) battery metals recovery from primary and secondary resources through a sustainable processing methodology. Any dissemination of results must indicate that it reflects only the author\u2018s view and that the Agency and the European Commission not responsible for any use that may be made of the information it contains. Image source: AdobeStock - 339395914, 406891094, 541126912, 566443983 Coordination: IDENER R&D \u00b7 Duration: 1 Jan. 2023 \u2013 31 Dec. 2026 Total Project Budget: 13.033.408,00 \u20ac \u00b7 EU Contribution: 11.798.783,25 \u20ac", "label": "poster"}
{"text": "c ACKNOWLEDGEMENTS CONCLUSION OBJECTIVES BACKGROUND REFERENCES The aim of this systematic review was to measure the impact of daily oral supplementation of vitamin D3 plus calcium on the incidence of hip fracture in older people. METHODS RESULTS THE IMPACT OF DAILY ORAL SUPPLEMENTATION OF VITAMIN D3 PLUS CALCIUM ON THE INCIDENCE OF HIP FRACTURE IN OLDER PEOPLE : A SYSTEMATIC REVIEW Preethy Manoj1 ,Dr .Rosemarie Derwin 2,Dr. Sherly George3 1 Royal College of Surgeons in Ireland, Dublin 2, 2Lecturer, School of Nursing & Midwifery, RCSI, Dublin 2 3 Lecturer & Programme Director, School of Nursing & Midwifery , RCSI, Dublin 2 Hip fractures reduce the quality of life and increase mortality. Osteoporosis is the biggest cause of fracture in older people (Nowson 2010).. It is estimated that by 2025, there will be approximately 28,000 new fragility fracture cases in Ireland costing \u20ac320 million (The Irish Times 2018)..The role of Vitamin D3 and Calcium in bone health is well known. The efficacy of daily oral supplementation of calcium plus vitamin D3 on the incidence of hip fracture and non-vertebral fracture in older men and women with or without risk of fracture remain equivocal. This review aims to fill this gap in the understanding. A systematic review with meta-analysis. was carried out. The databases such as CINAHL, MEDLINE, PubMed, Embase, and Cochrane Library were used to search the key terms along with Wiley Online library, HSE online library and Google Scholar. Also, the reference list of the retrieved articles was scanned to identify more studies. The search was conducted from October 2019- January 2020. The Cochrane risk of bias tool was used to check the quality of the included studies. A meta-analysis using Revman 5.3 was used to analyse the data. You probably won\u2019t have any symptoms in early-stage osteoporosis. Once your bones get weak enough, you might start having back pain from fractured or collapsed vertebrae. You may also start leaning forward in a stooped position and measure an inch or two less than before your bone loss. Figure 1 forest plot on the incidence of hip fracture A total of 12,620 older people, both men and women participated in seven RCTs evaluating the impact of combined daily oral supplementation of cholecalciferol and calcium on the incidence of hip fracture in older adults. This review identified a 25% reduction in hip fracture and a 20% reduction in all non-vertebral fractures among older adults who received Vitamin D3 and Calcium supplementation. Vitamin D3 plus calcium supplementation did not show any remarkable increase in the femoral neck bone mineral density. The subgroup analysis identified that daily oral supplementation of 800 IU of vitamin D3 plus 1200 mg of calcium is more effective in reducing hip fracture compared to 800 IU vitamin D3 plus 1000 mg of calcium. The findings of this review serve as a guideline in practice, education, research, and policy. Nonetheless, there is need for well-structured randomised controlled trials evaluating the effectiveness of Vitamin D3 plus calcium on the incidence of hip fracture and other fractures in older people. Nowson, C.A. (2010) Prevention of fractures in older people with calcium and vitamin D. Nutrients, 2(9), pp.975 The Irish Times. (2018) Retrieved from https://www.irishtimes.com/life-and-style/health-family/fitness/the- osteoporosis-time-bomb-1.3425377 on 30/10/2019. 984. I would like to extend my sincere gratitude to the exceptional Staff in the School of Nursing and Midwifery in the Royal College of Surgeons in Ireland whose lectures, guidance and supervision helped me to complete this project.", "label": "poster"}
{"text": "Ra Influence of Liquid/Gas ratio and alkalinity on photosynthetic biogas upgrading efficiency in an outdoors tubular photobioreactor David Mar\u00edn1, Antonio Ort\u00edz2, Enrica Uggetti2, Joan Garc\u00eda2, Raquel Lebrero1, Ra\u00fal Mu\u00f1oz1,* 1 Department of Chemical Engineering and Environmental Technology, Valladolid University. * mutora@iq.uva.es 2 GEMMA-Environmental Engineering and Environmental Group, Universitat Polit\u00e8cnica de Catalu\u00f1a INTRODUCTION \u2022 Biogas from the anaerobic digestion of solid wastes constitutes an important energy source able to decrease the dependence on fossil energy in our current society. \u2022 The use of biogas as a substitute of natural gas or fuel in transportation requires an effective purification to levels set by international regulations. Biogas injection into natural gas grids typically requires concentrations of CH4 \u226595%, CO2 \u22642%, O2 \u22640.3% and negligible amounts of H2S. \u2022 Algal-bacterial processes have emerged as a cost effective and environmentally friendly alternative for biogas upgrading compared to conventional physical/chemical or biological technologies. \u2022 Bahr, M., D\u00edaz, I., Dominguez, A., Gonz\u00e1lez S\u00e1nchez, A., Mu\u00f1oz, R., 2014. Microalgal-biotechnology as a platform for an integral biogas upgrading and nutrient removal from anaerobic effluents. Environ. Sci. Technol. 48, 573\u2013581. doi:10.1021/es403596m \u2022 Mar\u00edn, D., Posadas, E., Cano, P., P\u00e9rez, V., Blanco, S., Lebrero, R., 2018. Seasonal variation of biogas upgrading coupled with digestate treatment in an outdoors pilot scale algal-bacterial photobioreactor. Bioresour. Technol. 263, 58\u201366. https://doi.org/10.1016/j.biortech.2018.04.117 \u2022 Mu\u00f1oz R., Meier L., D\u00edaz I. and Jeison D. (2015) A review on the state-of-the-art of physical/chemical and biological technologies for biogas upgrading. Rev. Environ. Sci. Biotechnol. 14:727\u2013759 Aknowledgments: This work was supported by the project INCOVER. The project has received funding from the European Union\u2019s Horizon 2020 Research and Innovation Programme under the grant agreement No. 689242. MATERIALS AND METHODS RESULTS AND DISCUSSION CONCLUSIONS Microalgae BioFertilizer H2S CO2 BioCH4 SO4 2- O2 Solar Energy Digestate Organic Waste Anaerobic Digester Biogas \uf0a7CH4 \uf0a7CO2 \uf0a7H2S Aims of this study: \u2022 Study the influence of the liquid/gas ratio on the quality of the upgraded biogas. \u2022 Evaluate the influence of alkalinity on the absorption column. Two experimental series were conducted: \u2022 During the first experimental series, biogas was sparged into the absorption column (AC) under co-current flow operation in order to evaluate the influence of the liquid/gas ratio (L/G). \u2022 During the second experimental series, the influence of the alkalinity on the AC was studied. Biogas was sparged into the AC under co-current flow operation with an addition of a carbonate solution (NaHCO3 and Na2CO3) with a concentration of 16000 mg L-1 of inorganic carbon (IC) Experimental Set-up used for this study Evaluation of the liquid/gas ratio in the absorption column L/G Ratio Liquid Volume (L d-1) Biogas Volume (L d-1) 0.5 50 100 1.0 100 100 2.0 200 100 3.0 300 100 4.0 400 100 5.0 500 100 Evaluation of the influence of alkalinity on the absorption column L/G Ratio IC Concentration (mg L-1) Carbonate Solution (L d-1) 0.5 16000 0 1 2 3 5 The increase in the L/G ratio mediated a higher desorption of O2 and N2, which negatively impacted the final concentration of CH4 in the upgraded biogas. REFERENCES \u2022 To the best of our knowledge, this research constitutes the first evaluation of the use of microalgae for biogas upgrading under outdoors conditions at a pilot scale. \u2022 This research confirmed the key role of the liquid/gas ratio on the biogas upgrading efficiency. \u2022 The results herein obtained confirmed the key role of alkalinity on the biomethane quality. Evaluation of the liquid/gas ratio in the absorption column Evaluation of the influence of alkalinity on the absorption column Liquid Recirculation Pump Biogas Pump External Liquid Recirculat", "label": "poster"}
{"text": "COOL STARS 21, Toulouse, France New insights into the rotational evolution of near-solar age stars from M 67 David Gruner1,2, Sydney A. Barnes1,3, and J\u00f6rg Weingrill1 1 Leibniz-Institute for Astrophysics Potsdam, Germany 2 University of Potsdam, Germany 3 Space Science Institute, Boulder, CO, USA dgruner@aip.de CONTEXT AND MOTIVATION Gyrochronology allows the derivation of ages for cool main sequence stars based on their observed rotation periods and masses, or a suitable proxy for the latter. It is increasingly well-explored for young FGK stars in open clusters, but few calibrators are available for stars with ages over 1 Gyr, and virtually none for late-K or M-type stars. Our work is aimed at such extensions. LIGHTCURVES FROM THE K2 M 67 SUPERSTAMP Stellar open clusters provide the best environment for related work, because they offer well-defined samples of coeval stars of the same composition. Ac- cordingly, we investigated the hitherto unstudied superstamp created during the Kepler/K2 mission for the 4 Gyr-old benchmark open Cluster M 67. We con- structed a list of cluster stars based on Gaia DR2 and obtained aperture pho- tometry lightcurves for them (cf. panel (a) of Fig. 1). The infamous K2 lightcurve systematics are tamed using a flux correction that models the position depen- dency of the flux (transition to panel (b), same figure), and a Principal Com- ponent Analysis (transition to panel (c), same figure). In the set of lightcurves produced, we identify 39 main-sequence cluster members that exhibit periodic variations ascribed to stellar rotation. 0.96 0.98 1.0 1.02 1.04 Aperture photometry (a) 0.96 0.98 1.0 1.02 1.04 Normalized flux Flux corrected (b) Gaia DR2 604969267746267520 (G \u2212RP)0 = 0.86 mag, G = 17.3 mag PCA 140 150 160 170 180 190 200 210 Time [BJD\u22122457100 d] 0.96 0.98 1.0 1.02 1.04 PCA corrected (c) One rotation, Prot = 26.0 Double dipping star Figure 1: Lightcurves of a sample star. Panel (a) shows the raw lightcurve from aperture photometry, panel (b) shows the lightcurve after a correction for the telescope jitter, and panel (c) shows the lightcurve after the application of a PCA-based trend correction. ROTATIONAL CLUSTER SEQUENCE OF M 67 We identified rotation periods in stars ranging from the turn-off point (G0) to mid-M stars (blue points in Fig. 2 ). Our data overlap in color range with the sample of Barnes et al. (2016) in the CMD and CPD, and extend it to much later type stars. We find that rotation periods for stars later than mid-K do not show the period increasing uniformly with color that is seen in younger clusters. They instead reach a minimum in period at late-K type before rising again towards the red. Figure 2: Color-Period diagram for M 67. Rotation periods from this work are in blue, while the ones from Barnes et al. (2016) are in orange. The highlighted star is the one shown in Fig. 1. THE BIGGER PICTURE Our M 67 results now confirm what was already suggested by an investigation of the 2.5 Gyr-old open cluster Ruprecht 147 (e.g., Gruner & Barnes 2020, Curtis et al. 2020). 2.5 \u2013 4 Gyr-old stars later than early-K rotate faster than anticipated. This contradicts certain prior pre- dictions and suggests the involvement of a third distinct physical process for an accurate description of rotational evolution. However, our data confirm that cool stars continue to populate a single surface in rotation period-age-mass space until at least 4 Gyr. Furthermore, all three avail- able time steps for older stars (i.e., 1, 2.5, and 4 Gyr, Fig. 3 ) are clearly distinct in rotation period, an essential requirement for gyrochronology. 0.4 0.5 0.6 0.7 0.8 0.9 1.0 1.1 Color (G \u2212RP)0 [mag] 15 15 20 20 25 25 30 30 35 35 Rotation period P [d] This work Barnes et al. 2016 G0 K0 K2 K5 K7 M0 M1 M3 Spectral type References Barnes, S. A., Weingrill, J., Fritzewski, D., et al. 2016, ApJ, 823, 16 Curtis, J. L., Ag\u00fceros, M. A., Douglas, S. T., & Meibom, S. 2019, ApJ, 879, 4 Curtis, J. L., Ag\u00fceros, M. A., Matt, S. ", "label": "poster"}
{"text": "GEANT4 rendering of the EDELWEISS cryostat and the detectors. Experimen Due to their small size they have small hea The muon signals are very large and are affected by non-linearities of the TES We fit the muon pulse using a thermal model and extract thermal parameters that affect energy resolution. Development of transition-edge sensor based large area photon detectors for CUPID Vivek Singh, UC Berkeley Neutrino - 2020 (Poster # 97) CUPID: CUORE Upgrade with Particle ID Transition-edge sensors for photon detectors Next generation bolometric search for 0\ud835\udf08\ud835\udefd\ud835\udefd experiment. CUPID pre-CDR (arXiv:1907.09376) Detector performance V Singh 1, W Armstrong 2, G Benato 1, 3, M Beretta 1, C L Chang 4,5 , B K Fujikawa 3, K Hafidi 2, E Hansen 1, R Huang 1, G Karapetrov 6, Yu Kolomensky 1, 3, M Lisovenko 7,8, L Marini 1, Z Meziani 2, J Pearson 7, T Polakovic 2,6, B Schmidt 3, V Novosad 2,7, K J Vetter 1, S Wagaarachchi 1, G Wang 4, B Welliver 3, V Yefremenko 4, J Zhang 4 1 Department of Physics, University of California, Berkeley, Berkeley, CA. 2 Physics Division, Argonne National Laboratory, Chicago, IL. 3 Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA. 4 High Energy Physics Division, Argonne National Laboratory, Chicago, IL. 5 Kavli Institute for Cosmological Physics, University of Chicago, Chicago, IL. 6 Department of Physics, Drexel University, Philadelphia, PA. 7 Materials Science Division, Argonne National Laboratory, Chicago, IL. 8Nanoelectronics Department, Sumy State University, Sumy, Ukraine \u2022 Increase sensitive mass by enrichment \u2022 Active background rejection through \ud835\udefc / (\ud835\udefd-\ud835\udefe) separation \u2022 Goal: \u27a1\u25b3EFWHM \u2264 5 keV @ 2615 keV \u27a1B = 0.1 c/ton/y in ROI \u27a1 ~ 10 meV discovery sensitivity (10 yrs of live time) \u2022CUORE has successfully demonstrated that a ton scale bolometric experiment is feasible. \u2022CUPID will build on the experience of CUORE and use its cryogenic infrastructure. \u2022Li2MoO4 detectors recognized as baseline \u2022Enrichment > 95% \u2022~ 1500 crystals with ~ 250 kg of 100Mo \u2022Demonstrated active background rejection. [see Poster ID 419. on the CUPID-Mo experiment by Benjamin Schmidt] Rendering of CUORE cryostat with 1500 crystals inside it \u2022Dominant background is degraded alphas from surface contamination \u2022Leverage energy loss mechanism in the crystal to tag particle type \u2022Use auxiliary low temperature calorimeter to detect light. Should have High radiopurity Low heat capacity High photon collection efficiency Very low threshold (~ 100 eV) Excellent timing resolution to discriminate the 2\ud835\udf08\ud835\udefd\ud835\udefd pile up events from 0\ud835\udf08\ud835\udefd\ud835\udefd events. Particle ID \u2022Low transition temperature with relatively fast fabrication time possible with \u201cbilayers\u201d \u2022Negative electrothermal feedback keeps TES stable and decreases sensor time constant ; faster pulses \u2022Iridium goes superconducting at ~ 140 mK. We use the proximity effect of a normal metal (like, Au and Pt) to reduce the Tc. Device specification: \u20222\u201d Silicon wafer as optical photon absorber \u2022Ir/Pt (100 nm/60nm) bilayer with Nb traces as electrical leads. \u2022Transition temperature of ~ 37 mK \u2022Sensor dimension 300 \ud835\udf07m x 300 \ud835\udf07m \u2022 We have deposited Au pads, coupling the TES to the wafer for better phonon collection efficiency \u2022 Tc relatively unchanged with addition of Au pads but signal-to-noise improves drastically. square Ir/Pt bilayer TES square Ir/Pt bilayer TES in the middle with Au pads on both sides IV characteristics \u2022 We can operate the detector down to 10 mK by choosing a suitable bias point. \u2022 Due to the steep slope in the biased region, the sensitivity of a TES is much larger than NTD- Ge thermistors (CUORE like sensors) Timing resolution \u2022 Generate a train of blue LED light pulse with known separation time >> decay time \u2022 Examine distribution of trigger time between the subsequent pulses in detector response \u2022 Timing resolution of \ud835\udee5t ~ 5 \ud835\udf07s \u2022 Detector satisfies the criteria for rejecting 2\ud835\udf08\ud835\udefd\ud835\udefd pile up events (top) Detector response to train of LED pulses of varying amplitude inj", "label": "poster"}
{"text": "Reactivity of oxidising radicals with functionalised surfaces Wolstenholme-Hogg, Amy;a Iqbal, Naeem;a and Chechik, Victora aDepartment of Chemistry, University of York, Heslington, York YO10 5DD U.K. 1 Background 3 Computational modelling 6 Conclusions 1. Ulman A. Formation and Structure of Self-Assembled Monolayers. Chemical Reviews. 1996;96(4):1533-54. 2. De Keer L, Van Steenberge P, Reyniers M-F, Gryn'ova G, Aitken HM, Coote ML. New mechanism for autoxidation of polyolefins: kinetic Monte Carlo modelling of the role of short-chain branches, molecular oxygen and unsaturated moieties. Polymer Chemistry. 2022;13(22):3304-14. 3. Smith LM, Aitken HM, Coote ML. The fate of the peroxyl radical in autoxidation: how does polymer degradation really occur? Accounts of chemical research. 2018;51(9):2006-13. \u2022 The studies using mixed monolayers with radical initiators have shown degradation of the neighbouring chains, suggesting autoxidation does occur in monolayer systems. \u2022 These findings counteract the kinetic model, which showed no alkane degradation should occur due to the rate of peroxyl radical termination being much higher than H-abstraction by a peroxyl radical. \u2022 However, the results support the statistical model which suggest the majority of peroxyl radicals would be too far away from each other to react. Therefore, they can only react with neighbouring organic chains or atmospheric molecules. Non-porous silica nanoparticles have been used as model substrates. Approx. 2.5 molecules/nm2 TGA 0 20 40 60 80 100 120 140 f1 (ppm) 0 50000 100000 150000 200000 250000 i6042c.1.fid AVIIIHD400WB Carbon-13 100MHZ 2.5mm i6042c Amy Wolstenholme-Hogg AWH-C8 20 Solid state 13C NMR Si O O O Silica NPs 10-20nm Radical generation within monolayers Oxidative cleavage of the molecules from the silica surface enables the analysis and quantification of the molecular structures after reactivity by 1H NMR and GC-MS. GC-MS 1H NMR Using 1H NMR and GC-MS, the degradation of neighbouring chains can be monitored to give an understanding of the extent to which radical reactions propagate throughout the monolayer systems after exposure to UV light. The critical step is whether the newly formed peroxyl radicals continue to abstract a H from a neighbouring chain and the propagation of radical reactions occurs or whether they undergo termination to form stable products. Radical propagation Peroxyl termination \u2022 Reaction of the sensor surface with an \u2022OH can result in the oxidation of several molecules in the monolayer through autoxidation. \u2022 This could increase the sensor sensitivity but also reduce its lifetime. \u2022 The aim is to assess the degree of autoxidation \u2013 the spreading of radical reactions laterally in the monolayer. 1 2 a a b c c c c b a b c 1) Initiation 2) Reaction with O2 3) Peroxyl radical formation 4) Peroxyl radical termination 4) Radical propagation OR Silica surface 2 Project Aims Functionalisation of silica surfaces \u2022OH 1.8 x10-9 L mol-1 s [2] Statistical model Kinetic model 4 Methodology Dissociation of molecules from silica surfaces Si O Si O Si MeO OMe O O NP surface UV radical initiator (Surface bound) Si O Si O Si MeO OMe N N N N N N N N Thermal radical initiator (Surface bound) Si O Si O Si MeO OMe N N N N N N N N N N N N Thermal radical initiator (Not surface bound) NP surface NP surface UV radical initiation Silica nanoparticles have been functionalised with mixed monolayers of an organic molecule with a radical initiator. Silica surface \u2022 Assume 10% of the molecules in a monolayer form active radicals at a given time. \u2022 Random generation of 10% points in a grid. Minimum distances plotted as distribution. \u2022 5 molecules/nm2. \u2022 Distance between molecules 0.6 nm. \u2022 Length of monolayer chains ~0.6 nm \u2022 46% ROO\u2022 are close enough to react. \u2022 54% ROO\u2022 are more likely to propagate than terminate in monolayer systems. O O O O O O O O F F F F 5 F F F F F 5 F NP surface NP surface NP surface ether alkane perfluoro \u2022 Functionalised nanoparticles", "label": "poster"}
{"text": "Habitability conditions and radio emission under calm and extreme space weather conditions around Proxima b Luis Pe\u02dcna-Mo\u02dcnino1, Miguel P\u00b4erez-Torres1, Jacobo Varela2 & Philippe Zarka3 1CSIC, Instituto de Astrof\u00b4\u0131sica de Andaluc\u00b4\u0131a, Granada, Spain 2 Institute for Fusion Studies, University of Texas, Austin, TX 78712, United States, 3 LESIA, Observatoire de Paris, CNRS, PSL, SU/UPD, Meudon, France We acknowledge support through the Severo Ochoa grant CEX2021-001131-S and the Spanish National grant PID2020-117404GB-C21, funded by MCIU/AEI/ 10.13039/501100011033. LPM also acknowledges funding through grant PRE2020-095421, funded by MCIU/AEI/10.13039/501100011033 and by FSE Investing in your future. We also acknowledge the Spanish Prototype of an SRC (SPSRC) service and support financed by the Spanish Ministry of Science, Innovation and Universities, by the Regional Government of Andalusia, by the European Regional Development Funds and by the European Union NextGenerationEU/PRTR. MOTIVATION and GOALS MOTIVATION: \u2022 Habitability of exoplanets hosted by M dwarfs drastically depends on space weather. \u2022 Main players: ram and magnetic pressure of stellar wind + magnetic field of exoplanet. \u2022 Most likely drive radio emission arising close to the planet. GOALS: \u25b6Characterize habitability of the Earth-like planet Proxima b using 3D MHD simulations. \u25b7Calm and extreme space weather conditions. \u25b7Study role of stellar wind and planetary magnetic field, and their mutual orientation. \u25b6Determine radio emission arising from interaction between the stellar wind of Proxima and the magnetosphere of its planet Proxima b. MHD simulations - We used PLUTO: open 3D magneto-hydrodynamic code Main parameters of the PLUTO simulations Parameter Calm space weather Extreme space weather Sub-Alfv\u00b4enic Super-Alfv\u00b4enic CME scenario scenario scenario nsw [cm\u22123] 50 50 250 |vsw| [\u00d7 107 cm s\u22121] 5 10 25 BIMF [mG] 3.2 1.6 16 BProxima [G] 1200 600 600 BProxima b [G] 0.16\u22121.28 0.16\u22121.28 0.16\u22120.64 i [degrees] [0 - 90] [0 - 90] [0 - 45] \u25b6Sub-Alfv\u00b4enic scenario: \u03c1sw v 2 sw < B2 sw/(8 \u03c0) \u25b6Super-Alfv\u00b4enic scenario: \u03c1sw v 2 sw > B2 sw/(8 \u03c0) (Bow shock is formed) \u25b6Coronal mass ejection: Super-Alfv\u00b4enic scenario, with both \u03c1sw v 2 sw and B2 sw/(8 \u03c0) increased enormously for short time period. HABITABILITY - Magnetopause standoff distance as a proxy for planetary shielding - Life not that harsh in Proxima b! 0 20 40 60 80 Tilt(deg) 1 2 3 4 5 Rmp/RProxima b Sub-Alfv\u00e9nic Standoff distance 0 20 40 60 80 Tilt(deg) 1 2 3 4 5 6 7 Rmp/RProxima b Super-Alfv\u00e9nic Standoff distance 0 10 20 30 40 Tilt(deg) 1.5 2.0 2.5 3.0 3.5 Rmp/RProxima b CME Standoff distance 0.64G 0.32G 0.16G 0.2 0.4 0.6 0.8 1.0 1.2 BProxima b(G) 4 5 6 7 8 9 Rmp/RProxima b Sub-Alfv\u00e9nic Standoff distance 23 deg 0 deg 0.2 0.4 0.6 0.8 1.0 1.2 BProxima b(G) 6 7 8 9 10 11 12 Rmp/RProxima b Super-Alfv\u00e9nic Standoff distance 23 deg 0 deg 0.2 0.3 0.4 0.5 0.6 BProxima b(G) 1.5 2.0 2.5 3.0 3.5 Rmp/RProxima b CME Standoff distance 45 deg 23 deg 0 deg \u2022 Shielding decreases as tilt increases (top). \u2022 Shielding increases as intrinsic planetary magnetic field increases (bottom panels). \u25b6Calm space weather: If magnetic field of Proxima b similar to that of the Earth (Bp = B\u2295\u22480.32 G) or larger, magnetopause standoff distance is large enough to shield the surface from the stellar wind for essentially any planetary tilt. \u25b6Coronal mass ejection (CME): Proxima b well shielded if magnetosphere Earth-like (Bp\u2248B\u2295), or tilt smaller than that of Earth (i \u2248i\u2295\u224823.5 deg). RADIO EMISSION - Detection prospects - Radio emission very high under Super-Alfv\u00b4en and CME-like conditions. Caveat: Low frequency 0 20 40 60 80 Tilt(deg) 0.6 0.8 1.0 1.2 1.4 1.6 1.8 2.0 P(1019erg/s) Sub-Alfv\u00e9nic Magnetopause 0 20 40 60 80 Tilt(deg) 0.2 0.4 0.6 0.8 1.0 P(1019erg/s) Super-Alfv\u00e9nic Magnetopause 0 20 40 60 80 Tilt(deg) 2.4 2.5 2.6 2.7 2.8 P(1019erg/s) Super-Alfv\u00e9nic Bow Shock 0 10 20 30 40 Tilt(deg) 2 4 6 8 10 12 P(1021erg/s) CME Total Emission 0.64G 0.32G 0.16G 0.2 0.", "label": "poster"}
{"text": "3D Climate Modelling of TRAPPIST-1 c with a Venus-like atmosphere: Large-scale circulation and observational prospects D. Quirino1,2, G. Gilli1,3, T. Navarro4,5, M. Turbet6, T. Fauchez7,8, P. Machado1,21.InstituteofAstrophysicsandSpaceSciences(IA),Lisbon,Portugal(dfquirino@fc.ul.pt);2.FacultyofSciences,UniversityofLisbon,Lisbon,Portugal;3.InstituteofAstrophysicsofAndalusia(IAA\u2013CSIC),Granada,Spain(gilli@iaa.es);4.TheMcGillSpaceInstitute,Montr\u00e9al,QC,Canada;5.SpaceScienceInstitute,Boulder,CO,UnitedStates;6.LaboratoiredeM\u00e9t\u00e9orologieDynamique/IPSL,CNRS,SorbonneUniversit\u00e9,\u00c9coleNormaleSup\u00e9rieure,PSLResearchUniversity,\u00c9colePolytechnique,75005Paris,France;7.NASAGoddardSpaceFlightCenter,Greenbelt,MD,UnitedStates;8.AmericanUniversity,Washington,DC,UnitedStates . Introduction\uf0a7The population of close-in Earth-sized exoplanets orbiting late-type M-dwarf stars has increased in the recent years (e.g., [1, 2]), creating an unique opportunity: best targets for terrestrial planets atmospheric studies. Methods Thermal Structure \uf0a7TRAPPIST-1 c atmosphere is warmer than Venus\u2019s at and above the cloud deck region. \uf0a7The substellar and nightside equatorial profiles are similar from the ground to p ~ 0.01-bar. Between ~20-bar and ~ 0.01-bar, the nightside equatorial region [22.5\u00ba N/S] is warmer than the remaining nightside hemisphere, suggesting that a day-night heat redistribution mechanism is present in the equatorial region and throughout a significant atmospheric region. Thermal phase curves & transmission spectra Objectives Large-scale circulation Fig. 3. (Above) Time-averaged (10 orbits) temperature profiles for different regions of TRAPPIST-1 c, compared to the Venus International Reference Atmosphere (VIRA) profile. The red (blue) cross depict the approximate level of sulphuric acid condensation (freezing) point on Venus. Fig. 4. (Left). Zonal and time-averaged zonal wind field. The solid thick (thin) black lines represent isotachs with a 50 m/s (25 m/s) interval.\uf0a7Zonal circulation: eastward equatorial superrotationjet peaking 300 m/s in the uppermost levels of the atmosphere with a clear signature at the cloud top (p~37-mbar). \uf0a7Meridional circulation: two large cells, one per hemisphere (north and south), crossing the pole and redistributing heat f rom dayside to nightside. Fig. 5. (Above). Zonal and time-averaged mass streamfunctions: (a) dayside and (b) nightside. The integration exclude the terminators. Positive (negative) values, i.e., in red (blue), correspond to clockwise (anti-clockwise) motion. Fig. 6. (Left). Relation between thermal phase curves, outgoing long-wavelength radiation (OLR) and temperature fields. In the subplot a the red/blue arrows indicate the longitude corresponding to the orbital phase of peak emission, while the two-head arrow indicate each phase curve amplitude. Orbital phase 0 corresponds to the secondary eclipse, while \u03c0is the planetary transit. In subplots (b) and (c) the red/blue cross marks the longitude of the maximum peak emission over the equator. All data is time-averaged for ten orbits of TRAPPIST- 1 c.Fig. 7. (Above) Transit transmission spectra of TRAPPIST-1 c for JWST NIRSpecPrism (0.6 \u20135.3 \u03bcm) andMIRI (5 \u201320 \u03bcm) for: Venus-likeclouds(blue) andclear-sky(black), simulatedwiththePlanetarySpectrumGenerator . \uf0a7Different atmospheric levels can be surveyed with different thermal spectral bands: o CO2 absorption bands will sound mesospheric levels (p ~1-mbar) o Continuum bands will sound the cloud top (p ~ 37-mbar) CO2 absorption bands: larger amplitudes and later peak emission Smaller eastward hotspot offset\uf0a7Venus-like clouds will screen almost all but the strongest CO2absorption bands in the transmission spectra. The 4.8-\u03bcm CO2might become detectable, which could indicate the presence of a high-pressure CO2 a tmosphere. \uf0a7We use the Generic-PCM initially developed by the Laboratoire de M\u00e9t\u00e9orologie Dynamique (Paris, France) for exoplanet and paleoclimate studies [13 - 15]. \uf0a7The Generic-PCM includes a dynamic", "label": "poster"}
{"text": "KDAR Neutrino Measurements with JSNS2 Johnathon Jordan for the JSNS2 Collaboration University of Michigan Poster #482 Proton Beam Linear Accelerator RCS MLF MLF Beam Layout Mercury Target When charged kaons decay at rest, they can produce monoenergetic neu- trinos from the two-body decay: These known-energy kaon de- cay-at-rest (KDAR) neutrinos can be used to make a variety of interesting physics measurements. KDAR Neutrino Proton Neutron KDAR Neutrino Neutrino-induced Nuclear Excitations Neutrino-Nucleon Interactions *Cartoon KDAR Neutrino Basics The MLF Neutrino Source KDAR neutrinos offer a standard candle to benchmark neutrino interac- tion models relevant for future oscilla- tion experiments [1]. Their intermedi- ate energy allows them to probe the transition between neutrino-nucleus and neutrino-nucleon scattering [2]. KDAR neutrinos can also be used for a variety of other measurements [3,4]. The J-PARC Material and Life Science Experimental Facility (MLF) is a spall- ation neutron source in Japan. A high intensity proton beam is accelerated to 3 GeV by the Rapid Cycle Synchrotron (RCS) and delivered to a liquid mercury target in the MLF. In addition to provid- ing a world-class spallation neutron source, the mercury target is also an intense source of decay-at-rest (DAR) neutrinos. The MLF design beam power is 1 MW and the beam power has been steadily increasing (in June beam power has been ~610 kW). The 3 GeV beam energy is high enough for kaons to be produced in the target where they quickly slow down and decay at rest. This fact combined with the high beam intesnity makes the MLF the best place in the world to do physics with KDAR neutrinos. 104 105 106 107 Neutrino Flux (Arb. Units) \u00b5 \u03c0 K \u2212600 \u2212400 \u2212200 0 200 400 600 800 1000 Time (ns) 0 20 Current (A) \u00d725 Hz Beam Pulses 0 100 200 300 -8 10 -7 10 -6 10 -5 10 -4 10 -3 10 -2 10 -1 10 Energy (MeV) \u03bd/POT/2 MeV The JSNS2 Experiment Neutrino Flux + Timing \u03b8 2 2 sin 4 \u2212 10 3 \u2212 10 2 \u2212 10 1 \u2212 10 1 ] 4 /c 2 [eV 2 m \u0394 2 \u2212 10 1 \u2212 10 1 10 2 10 90%C.L 2 JSNS LSND 99%C.L LSND 90%C.L OPERA(2013) 90%C.L 1 MW x 3 years exposure 1 detector (17 tons \ufb01ducial) Protons are delivered to the MLF at 25 Hz in two pulses. Neutrinos from kaon decays are produced in time with the beam due to the short kaon lifetime. The low duty factor of the beam re- duces beam-off backgrounds to KDAR neutrino measurements. Most neutrino parents decay at rest in the target and shielding, so the result- ing neutrino \ufb02ux largely consists of well-understood decay-at-rest compo- nents. Thus, decay-in-\ufb02ight (DIF) neu- trino backgrounds to KDAR neutrinos are small. The J-PARC Sterile Neutrino Search at the J-PARC Spallation Neutron Source (JSNS2) [5] is a short baseline neutrino oscillation experiment. JSNS2 is de- signed to search for oscillations with \u2206m2 ~ 1 eV2 using the double coincidence signature of IDB (prompt positron, delayed neutron capture). JSNS2 has collected 10 days of initial data this month (expected to contain 200-400 KDAR events) and will continue operation in the fall. JSNS2 utilizes a liquid scintillator (LS) neutrino detector consisting of an inner volume \ufb01lled with gadolini- um-doped LS and outer buffer and veto regions \ufb01lled with undoped LS. Scintillation light is collected by 120 10-inch PMTs including 24 PMTs in the veto region used to reject activity origi- nating outside the detector. There is additional shielding under the detec- tor to reduce environmental gamma backgrounds produced in the concrete hatch the detector sits on. KDAR Signatures in JSNS2 References + Acknowledgements \u001b\u001a\u0019\u0018\u0017\u0016\u0015\u0014\u001b \u0018\u001b\u001a\u0017 \u0013\u0015\u0017\u0012\u0019 \u0011\u0010 \u000f\u0011\u000e\u0012\u001a\u000e\u0016\u0016 \u001a\u000e\u0017\u0012\u0019 \u000e \u001a \u0017\u001a\u0017\u0012\u0019 \u0011\u0010 \u000f \u000f\b\u0019\u0007\u001b\u001a\u001b\u0011\u001a\u0017 \u0006\u0007\u0005\u0004\u0019 \u000e\u0014\u000e\u0012 \u0019\u000f\u000e \u0012 \u001a\u0015 \u001b Other JSNS2 Posters JSNS2 is most sensitive to KDAR neutri- no charged current interactions. In most events, the expected event sig- nature is a double coincidence be- tween the initial neutrino interacion products and the subsequent muon decay (lifetime ~2.2 \u03bcs): In ~20% of interactions, the \ufb01nal state is also expected to con", "label": "poster"}
{"text": "Team design for team science Emerging Methods and Tools for Sparking New Global Creative Networks COINs15 Tokyo \u2013 Jeff Horon, Consultant, Elsevier Research Intelligence \u2013 http://jeffhoron.com Emerging methods and tools are changing the ways participants in global creative networks become aware of each other and proceed to interact. Some web-based resources intended to spark new collaborations in creative networks have been plagued by dependence on fragmented or out-of-date information, having shallow recall (e.g. limited to a list of manually curated keywords), offering poor interconnectivity with other systems, and/or obtaining low end-user adoption. Increased availability of information about creative network participants' activities and outputs (e.g. completed sponsored research projects and published results, aggregated into global databases), coupled with advancement in information processing techniques like Natural Language Processing, enables new web-based technologies for discovering subject matter experts, facilities, and networks of current and potential collaborators. Large-scale data resources and NLP allow modern versions of these tools to avoid the problems of having sparse data and also provide for deep recall across many disciplinary vocabularies. These are \"passive\" technologies, from the perspective of the network participant, because the agent must undertake an action to use the information resources. Emerging \"active\" methods and tools utilize the same types of information and technologies, but actively intervene in the formation of the creative network by suggesting connections and arranging virtual or physical interactions. Active approaches can achieve very high end-user adoption rates. Both active and passive methods strive to use data-driven approaches to form better-than-chance awareness among networks of potential collaborators. Recent case studies suggest the existence of repeatable strategies for facilitating data-driven matching and better-than-chance interactions designed to spark new global creative networks. Abstract Active / Interventional Networking Methods Passive Networking Suggested casual interactions at physical events and These emerging methods and tools suggest the existence of repeatable strategies for facilitating data-driven matching and better- than-chance interactions designed to spark new global creative networks. As these methods become further systematized and see wider adoption, they are poised to influence larger numbers of creative networks and their participants. Conclusions scheduled interactions at physical events Identification via mining network structures Outcomes Identification via survey / self-identification Arrange researchers and concepts into a self-organizing bipartite network Eliminate matches that already collaborate The remainder are suggested matches\u2026 \u2026. with suggested conceptual connections Participants specify interests, expertise, and needs (often discipline-specific) Score potential matches Issue recommendations", "label": "poster"}
{"text": "Polyolefin Family Polymers for Drug Delivery Applications CD Bioparticles, a leading manufacturer and supplier of numerous drug delivery products and services, has recently expanded its low PDI polymer portfolio and announces its new offering of Polyolefin Family polymers with a wide range of properties that make them well-suited for a variety of drug delivery applications. Low dispersion index polymers are polymeric compounds with low molecular weight dispersion. Typically, the structures of such polymers are designed to reduce their dispersion in solution, thereby improving their stability and controllability. They\u2019re widely used as drug carriers mainly because of their ability to efficiently carry and release drug molecules, thereby improving drug bioavailability and therapeutic efficacy. The design of such drug carriers also helps to overcome some of the limitations of conventional drugs such as biostability, water solubility and drug distribution in the body. The Polyolefin family is a class of polymers derived from simple hydrocarbons with a wide range of promising drug delivery applications. These materials, which include polyethylene and polypropylene, have a number of unique properties suitable for various pharmaceutical applications. For example, Polyolefins' inertness, biocompatibility, and ability to be tailored to specific drug release profiles make them particularly attractive for the design of drug delivery systems. In addition, Polyolefin-based drug delivery systems offer excellent stability, ensuring that drug formulations remain intact over time. The biodegradability and minimal toxicity of Polyolefins also make them attractive for the development of sustained-release formulations. Moreover, the tunable properties of Polyolefins allow modulation of drug release kinetics, resulting in precise control of the therapeutic dose. This family of polymers has proven advantageous in improving the efficacy and safety of drug release and overcoming the challenges associated with conventional formulations. As research continues, the Polyolefin family will continue to attract the attention of scientists and pharmaceutical experts, demonstrating its potential to revolutionize drug delivery strategies and improve patient outcomes. CD Bioparticles recognizes the potential of the Polyolefin family for pharmaceutical applications and has developed innovative drug delivery systems using Polyolefins based on their inherent properties. The company is committed to working with partners on a number of research and development projects aimed at delivering a variety of drugs using Polyolefins and bringing these novel drug delivery systems to market. Furthermore, CD Bioparticles strives to make further groundbreaking contributions to the field of drug delivery and will continue to honor its commitment to innovation.", "label": "poster"}
{"text": "Is AD Leo entering a polarity reversal? Long-term monitoring of the large-scale magnetic field with ESPaDOnS, NARVAL and SPIRou Stefano Bellotti1,3, Julien Morin2, Lisa Lehmann1, Pascal Petit1, Gaitee Hussain3 and the SLS consortium 1: IRAP, Toulouse (FR), 2: LUPM, Montpellier (FR), 3: ESA/ESTEC, Noordwijk (NL) stefano.bellotti@irap.omp.eu Acknowledgements: Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council (NRC) of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique (CNRS) of France, and the University of Hawaii. The observations at the CFHT were performed with care and respect from the summit of Maunakea which is a significant cultural and historic site. We gratefully acknowledge the CFHT QSO observers who made this project possible. We acknowledge funding from ANR of France (SPlaSH), with PI Xavier Delfosse. Fig 1. Evolution of Bl. Left: optical (circles) and near-infrared (squares) time series between 2006 and 2020. Right: near-infrared time series phase-folded at the stellar rotation period. FWHM of Stokes I \u25cfFWHM useful activity tracer sensitive to Zeeman e\ufb00ect \u2192 high Land\u00e9 factor (ge\ufb00) lines can reveal activity signal \u25cfFull vs high-ge\ufb00 mask [12]: all FWHM values are larger in the latter case \u25cfConstant vs sine \ufb01t: the variations of the 2020b epoch are better described by sinusoid \ufb01t (22% decrease in residual RMS) Longitudinal magnetic \ufb01eld \u25cfDisk-integrated, line-of-sight component of the magnetic \ufb01eld (Bl) \u25cfStellar north pole is dominated by negative dipole all the time \u25cfGlobal decrease in \ufb01eld strength over 14 years \u25cfReduced axisymmetry indicated by varying amplitude in the phase-folded time series Fig 2. Phase-folded FWHM curves using full and high-geff masks for near-infrared epochs: 2019a (top), 2019b2020a (middle), 2020b (bottom) \u25cfIncreased FWHM variations imply lower degree of axisymmetry \u25cfFWHM phase variations are re\ufb02ected by ZDI maps Principal Component Analysis \u25cfApply PCA to mean-subtracted near-infrared Stokes V (2019-2020) to infer details on non-axisymmetric \ufb01eld [13, see also poster of L. T. Lehmann] Zeeman-Doppler Imaging \u25cfReconstruction of the large-scale magnetic \ufb01eld topology by means of a maximum-entropy algorithm Stellar magnetic cycles With a long-term monitoring of the large-scale magnetic \ufb01eld, we can search for temporal evolution of the topology and uncover stellar dynamo theories. The Sun is an important benchmark: the magnetic cycle is characterised by a 11-yr variation in sunspot number, size and latitude of emergence, and magnetic polarity reversal [1,2]. Spectropolarimetric observations revealed analogous polarity \ufb02ips also on other stars [3,4]. At the lower end of the main sequence, M dwarfs represent excellent laboratories to study non-solar dynamo mechanisms underlying the generation and preservation of magnetic \ufb01elds. Conclusions \u25cfVariations in the coe\ufb03cients are more sinusoidal and ampli\ufb01ed \u2192 large-scale \ufb01eld is dipolar and its axisymmetry decreases over time Fig 3. Evolution of PCA coefficients for the first three eigenvectors over the near-infrared epochs: 2019a (top), 2019b2020a (middle) and 2020b (bottom). \u25cfFirst three eigenvectors have signals \u2192 on average \ufb01eld is non-axisymmetric Fig 4. Evolution of ZDI map over near-infrared epochs: 2019a (left), 2019b2020a (middle) and 2020b (right). The magnetic maps are in flat polar view, with the north pole at the center and the equator marked by a solid line \u25cfThe geometry is poloidal (magnetic energy fraction >90%) and dipolar (>70%), as in 2006-2016 observations \u25cfAxisymmetry decreases from >85% to 48% in 2020b and tilt angle increases from 15o to 56o accordingly \u25cfDecreasing axisymmetry of the large-scale \ufb01eld con\ufb01rmed by di\ufb00erent techniques \u25cfGlobal evolution of the large-scale \ufb01eld of AD Leo possibly suggesting a magnetic cycle, in the strong aligned dipole category \u25cfDi\ufb00erence of longitudinal and ZDI \ufb01eld streng", "label": "poster"}
{"text": "Wake Forest University School of Medicine is the academic core of Atrium Health. \u2022 EPIC used to identify all sterile culture sites which grew Serratia Marscens or Liquifascens in our system \u2022 Queried 8/1/2016 - 4/15/2022 Julia Cook, MD; Matthew B Anderson, MD; Erin Barnes, MD, MS, FASAM. Infectious Diseases at Atrium Health Wake Forest Baptist Health A Case Series of Serratia Marcescens Infectious Endocarditis in Persons Who Inject Drugs Demographics Age (years) 29.5 Race N (%) Black 2 (9) White 20 (91) Gender Male 6 (27) Female 16 (82) HCV exposed 19 (86) Background Results \u2022 Serratia marcescens is a gram-negative bacillus that is widespread in the environment \u2022 Rare cases of endocarditis caused by this organism have been reported \u2022 Atrium Health Wake Forest Baptist (AHWFB) in North Carolina has experienced an increasing number of severe infections with Serratia marcescens, particularly in persons who inject drugs Methods Characteristics Bacteremia Duration xxxxx Substances Used N (%) Opioid Injected 16 (73) Stimulant Injected 3 (14) Stimulant Without Route Stated 10 (45) Blood Culture Serratia Only 16 (73) Polymicrobial 6 (27) Prior IE Episode 9 (41) Prosthetic Valve Present 4 (18) 9% 35% 43% 13% Valves Involved Aortic Mitral Tricuspid Pulmonic Complications Emboli N (%) Lung 10 (45) Cerebral 7 (32) Major Arterial 5 (23) Other Epidural abscess 1 (5) Septic Arthritis or Osteomyelitis 4 (18) Endophthalmitis 1 (5) Surgery and Disposition Surgery N(%) Aspiration 2 (9) Valve Repair 16 (73) Valve Replacement 3 (14) Disposition Deceased 4 (18) Left AMA 4 (18) Remained in AHWFB Facility for Duration 16 (73) Other\u2020 2 (9) \u2020One was transferred to another facility and one was discharged for daily infusions administered in an infusion center through peripheral IVs placed each day 284 \u2022 693 reports representing 293 individuals \u2022 9 removed for age less than 18 96 \u2022 188 without evidence of injection drug use 42 \u2022 54 did not meet criteria for at least possible endocarditis by Modified Duke Criteria 22 \u2022 Serratia was secondary to line infection \u2022 Serratia was not targeted for endocarditis treatment \u2022 Serratia was secondary to separate process \u2022 Injection drug use timeline not clear Discussion 9% 45% 5% 41% Final Regimen Deceased Beta-Lactam Alone Fluoroquinolone Alone Beta-Lactam + Fluoroquinolone \u2022 AHWFB has a large number of Serratia IE cases in PWID, the largest number reported in the US since a 1969-1974 series in the San Francisco Bay Area \u2022 Likely sources include contaminated tap water used for drug mixing \u2022 Further study to determine if this a regional or national trend is warranted as is study on the ideal treatment regimen", "label": "poster"}
{"text": "BIBLIOGRAPHICAL DATA WORKING GROUP For decades bibliographical information has been among the most widely-used resources in the humanities. \u201cBibliographical Data\u201d Working Group aims to foster cooperation between all the parties involved in bibliographic data life cycle in the humanities, especially between data creators, curators, researchers, developers, and theorists of documentation and bibliography. Data preparation for advanced research Facilitating international data-based cooperation Methodological issues Publishing bibliographies Processing bibliographic metadata Remediation of bibliographical information Development of user-oriented services IF YOU INTERESTED IN THE WG, PLEASE CONTACT US: Tomasz Umerle: tomasz.umerle@ibl.waw.pl Vojt\u011bch Mal\u00ednek: malinek@ucl.cas.cz @bibliodataWG Bibliographical Data Landscape Analysis Report data production and use analysis challenges and opportunities for public stakeholders crucial stakeholders public and private dimensions of the landscape Goals for 2020: MISSION STATEMENT: bibliodata software bibliodata in research bibliodata and scholarly primitives Bibliographical Data Workflows - Workshop advocating for a joint public stakeholders agenda bibliodata and LOD subject bibliographies Web archiving discovery platforms for bibliodata AREAS OF INTEREST 25th November 14:00 MORE INFORMATION ABOUT THE WORKSHOP AT: https://dariah-ae-2020.sciencesconf.org/309669", "label": "poster"}
{"text": "SWEET-cat: The cat is still sweeter! A catalog of stellar parameters for stars with planets S\u00e9rgio G. Sousa et al. Instituto de Astrof\u00edsica e Ci\u00eancias do Espa\u00e7o & Centro de Astrof\u00edsica da Universidade do Porto Abstract: This is a story of two cats that discover that astronomers have presented a sweet cat. What is this sweet cat? Are there cats in other worlds? Is there something more, something else? Top left: The metallicity distributions for two different populations classified according to the higher planetary mass in the system: low-mass planet hosts (LMPH: 99 planet hosts), and high-mass planet hosts (HMPH: 771 planet hosts) with homogeneous parameters from SWEET-Cat. The mass separation value is 30 earth masses. The very well known metallicity correlation is very clear for massive planet hosts, while stars hosting only low massive stars seems to be no different from the general population of stars. Top right: The updated version of SWEET-Cat contains accurate determination of surface gravities (orange points) which are computed using GAIA astrometry and photometry. For details, please see Sousa et al. 2021. Bottom right: Using the updated homogeneous spectroscopic parameters listed in SWEET-Cat we can still find a correlation in the metallicity-period-mass diagram hinting that the mass of planets increase with the period and the metallicity. This trend cannot be fully accounted by observational bias as demonstrated in Sousa et al. 2019. References: Sousa, S.~G., Adibekyan, V., Delgado-Mena, E., et al.\u037e 2021\u037e A&A, 656, A53. doi:10.1051/0004-6361/202141584 Sousa, S.~G., Adibekyan, V., Santos, N.~C., et al.\u037e 2019\u037e MNRAS, 485, 3981. doi:10.1093/mnras/stz664 Sousa, S.~G., Adibekyan, V., Delgado-Mena, E., et al.\u037e 2018, A&A, 620, A58. doi:10.1051/0004-6361/201833350 Andreasen, D.~T., Sousa, S.~G., Tsantaki, M., et al.\u037e 2017, A&A, 600, A69. doi:10.1051/0004-6361/201629967 Sousa, S.~G., Santos, N.~C., Mortier, A., et al.\u037e 2015, A&A, 576, A94. doi:10.1051/0004-6361/201425227 Santos, N.~C., Sousa, S.~G., Mortier, A., et al.\u037e 2013, A&A, 556, A150. doi:10.1051/0004-6361/201321286 Acknowledgments: S\u00e9rgio G. Sousa aknowledges the support from FCT through Investigador FCT contract nr. CEECIND/00826/2018 and POPH/FSE (EC). Check our last paper:", "label": "poster"}
{"text": "1 Georgia State University, 2 European Space Agency, 3 University of Hawaii Varun Chaturmutha1, Bernhard Fleck2, Stuart Jefferies1,3 Probing the Atmosphere of the Sun-As-A-Star Using Seismic Waves varun@astro.gsu.edu (2a) Layer Separation (2b) Sound Speed (2e) Sunspot Number (1a) Solar Surface-Resolved Data (8 hours) (1b) Sun-as-a-Star Data (1 Year) We use multi-height, line-of-sight Doppler velocity observations of the Sun, as if it were a distant star, to probe the properties the solar atmosphere via travel-time analysis of acoustic-gravity waves. Travel time data from surface-resolved observations of the Sun (1a) have been used historically to estimate atmospheric properties via wave models [1,2,3]. We transfer this technique to sun-as-a-star data (1b) to estimate separation between the observed layers (2a), sound speed (2b), radiative cooling time (2c), and the horizontal wavenumber (2d). (2c) Radiative Cooling Time (2d) Horizontal Wavenumber Website: astro.gsu.edu/~varun Linkedin: vchaturmutha Email: varun@astro.gsu.edu The atmospheric properties estimated using Sun-as-a-star data matches closely with surface-resolved observations of the Sun. The temporal evolution of atmospheric properties (2a, 2b, 2d), is strongly correlated with the solar cycle (2e) of the Sun. This suggests the potential of this technique to probe properties of stellar atmospheres and an alternate method to detect stellar cycle effect. The layer separation between multi-height spectra observations could enable astroseismic tomography of stellar atmospheres, radiative cooling times have implications for atmospheric heating, sound speed offers insights into the temperature structure, and horizontal wavenumber is related to the granular scales. Figure 1: Travel time spectra prepared using (a) surface resolved and (b) Sun-as-a-star, doppler velocities from Na D and Fe I spectral lines. Sun-as-a-star travel time in (b) is prepared by averaging 4 hours of data over 365 days. Figure 2: Temporal evolution of sin-as-a-star atmospheric properties: (a) separation between observing levels, (b) sound speed, (c) radiative cooling time, and (d) horizontal wavenumber. The Sunspot cycle evolution is shown in (e) as a proxy for magnetic activity on the sun. 1) Souffrin, P. 1972, A&A, 17, 458 2) Jefferies, S. M., Fleck, B., Murphy, N., & Berrilli, F. 2019, ApJL, 884, L8 3) Chaturmutha, V., Fleck, B., & Jefferies, S. M. 2024, ApJ, 966, 200 4) Pesnell, W. D., Thompson, B. J., & Chamberlin, P. C., 2012, SoPh, 275, 3 5) Scherrer, P. H., Schou, J., Bush, R. I., et al. 2012, SoPh, 275, 207 6) Forte, R. et al. 2018, in IAU Symp. 335, Space Weather of the Heliosphere: Processes and Forecasts, (Cambridge: Cambridge Univ. Press), 335 INTRODUCTION DISCUSSION DATA ANALYSIS R E S U L T S REFERENCES", "label": "poster"}
{"text": "ASSESSMENT OF LOOP-MEDIATED ISOTHERMAL AMPLIFICATION ASSAYS FOR ESCHERICHIA COLI DETECTION Mila Djisalov1, Ljiljana \u0160a\u0161i\u0107 Zori\u01071, Ljiljana Janju\u0161evi\u01071, Teodora Kne\u017ei\u01071, Ivana Gadjanski1 1University of Novi Sad, BioSense Institute, Dr Zorana \u0110in\u0111i\u0107a 1, 21000 Novi Sad, Serbia Corresponding author: mila.djisalov@biosense.rs INTRODUCTION: As of lately, loop-mediated isothermal amplification (LAMP) has become a powerful alternative to the polymerase chain reaction (PCR) in the molecular diagnostic world, especially for pathogen detection in clinical and food samples. LAMP is a powerful and new method of nucleic acid amplification, with the ability to detect DNA at a very low level. In comparison to other molecular methods such as PCR and Real-Time PCR, LAMP eliminates the need for sophisticated thermal cyclers. High efficiency of DNA amplification by LAMP significantly shortens the whole amplification process. OBJECTIVES: This study aims to assess the efficacy of two different LAMP kits, WarmStart (Real-Time LAMP) and Colorimetric LAMP in detection of Escherichia coli. We tested and optimized the kits for the detection of E. coli ATCC\u00ae 25922 directly from bacterial suspension and indirectly using bacterial genomic DNA (gDNA). LAMP results were then compared with the results of E. coli detection using standard PCR methodology. METHOD / DESIGN: For use in LAMP detection of E. coli directly from the bacterial suspension, we prepared eight bacterial dilutions in concentrations ranging from 1.5x108 - 1.5x101 CFU/mL. All bacterial dilutions were then used for LAMP detection using WarmStart Colorimetric LAMP 2X Master Mix (New England BioLabs) for colorimetric LAMP and WarmStart LAMP Kit (New England BioLabs) for Real-Time LAMP. Real-Time LAMP reactions were done on the Genie\u00ae II, an instrument for isothermal nucleic acid amplification (Figure 1). LAMP primers (F3, B3, FIP, BIP, LF, BF) (Figure 2) for the malB gene are taken from the literature. For indirect detection we extracted genomic DNA from E. coli using GeneJET Genomic DNA Purification Kit (Thermo Scientific). Extracted gDNA with the concentration 50 ng/\u03bcl was used for preparation of ten-fold dilutions (10-1 - 10-4), and these dilutions were used in both Colorimetric and WarmStart LAMP assays in order to compare limits of detection with and without DNA extraction. Finally, we used E. coli genomic DNA serial dilutions for standard PCR, using F3 and B3 primers for malB gene. RESULTS: The results showed that both LAMP methods (WarmStart and Colorimetric LAMP) enabled the detection of E. coli directly, in suspension (without prior DNA isolation) for bacterial concentration of 1.5 x 108 CFU/mL (Figure 3, Chart 1). Additionally, the results of Colorimetric LAMP using serial dilutions of E. coli gDNA showed detection in all tested concentrations, except the lowest (10-4) (Figures 4-5). On the other hand, the WarmStart LAMP kit enabled E. coli gDNA detection in all tested gDNA dilutions (Chart 2, Figure 6). The conventional PCR methods failed to detect E. coli malB gene product for the lowest DNA concentration (Figure 7.). Additionally, DNA bends on agarose gels are more intensive in the LAMP products compared to those obtained with PCR products. CONCLUSIONS: Presented research showed the incredible power of the LAMP methodology (both, Colorimetric and Real-Time) to detect E. coli even without prior isolation of bacterial gDNA. Also, LAMP enabled E. coli detection even at an extremely low concentration of tested gDNA (50 x 10-4 ng/\u03bcl), while with conventional PCR that was not the case. PCR managed to detect bacterial gDNA up to a concentration of 50 x 10-3 ng/\u03bcl. Based on these results, LAMP was proved to be more sensitive than PCR, with a large capacity to be used in molecular diagnostics. Also, LAMP is easier to handle since it is more time-efficient and can be performed using portable small devices suitable for on Point-of- Care (POC) research. Figure 1. Genie\u00ae II instrument for Real-T", "label": "poster"}
{"text": "The Bering Sea Project Archive: a Prototype for Improved Discovery and Access Don Stott, Matthew S. Mayernik, Michael D. Daniels, James A. Moore, Steven F. Williams, and John Allison NCAR Earth Observing Laboratory, Boulder CO, USA, stott@ucar.edu Science-focused use case examples \u2022 Identify a geospatial region via data where certain parameters show specific features. \u2022 Ex. #1: Find the areas in a defined region where benthic biomass is high for walruses to feed \u2022 Ex. #2: Is the line between benthic and pelagic dominated ecosystem shifting? \u2022 Find information (data, publications, products) related to a geolocated event. \u2022 Ex. #1: Information related to a ship cruise \u2022 Ex. #2: Information relevant to under ice CTD data collected in the South Bering Strait vivo.eol.ucar.edu The Earth Observing Laboratory (EOL), as a partner in the NSF funded EarthCollab project, is using linked open data to support scientific collaboration and increase the discoverability and usability of scientific resources. The EOL proof-of-concept Arctic Data Connects web application interlinks datasets from the Bering Sea Project Archive at EOL across platforms and projects. It provides researchers the means to more easily find people, organizations, and resources that are relevant to their work, via semantic and linked data. The Bering Ecosystem Study (BEST) was an NSF sponsored program that provided researchers an opportunity to gain an improved understanding of the linkages between variations in Bering Sea ice cover and the biology of the waters and benthos beneath. A collaborating program, the Bering Sea Integrated Ecosystem Research Program (BSIERP), sponsored by the North Pacific Research Board, collected data in the same region at the same time in an effort to improve understanding and prediction of ecosystem changes related to anthropogenic and natural causes. Over the six-year period of the programs hundreds of multidisciplinary datasets from a variety of instrumentation and measurement platforms within thirty-one categories of research were processed and curated by the NCAR/EOL. The separate BEST and BSIERP data archives were brought together to form the Bering Sea Project Archive in 2010. The EOL organized and continues to maintain the Bering Sea Project Archive as the single source for all data from the combined efforts of the BEST and BSIERP programs. The Bering Sea Project Archive incorporating the BEST-BSIERP Data Archives http://beringsea.eol.ucar.edu Data Linkage with Derived Datasets NSF award numbers are used here to connect datasets and Principal Investigators. As more datasets receive DOIs (Digital Object Identifiers), the DOI will be utilized to link derived products. EarthCollab Data Structures Build ontology extensions for linking: \u2022 VIVO-ISF: People, organizations, publications \u2022 DCAT: data sets and catalogs \u2022 GCIS: Scientific instruments, platforms, projects \u2022 Local ontology development to fill gaps Yet to model: \u2022 Geospatial and temporal features \u2022 Parameters/variables \u2022 Use case specific features, e.g. ship tracks EarthCollab is funded by the US National Science Foundation EarthCube program, grants #1440293, 1440213, 1440181, PIs Matthew Mayernik, Mike Daniels, Dean Krafft, and Linda Rowan. Underlying Technology The heterogeneous products of oceanographic field programs such as the Bering Sea Project challenge the ability of researchers to identify which data sets, people, or tools might be relevant to their research, and to understand how certain data, instruments, or methods were used to produce particular results. Arctic Data Connects is employing the open-source semantic web software, VIVO, as the underlying technology to connect the people and resources of virtual research communities. VIVO is being leveraged to address connectivity gaps across distributed networks of researchers and resources and to identify relevant content, independent of location. http://vivoweb.org", "label": "poster"}
{"text": "Plataforma para la creaci\u00f3n de servicios el\u00e1sticos big data analytics en la nube Este proyecto ha sido financiado por IVACE y FEDER, a trav\u00e9s de la convocatoria de ayudas dirigidas a centros tecnol\u00f3gicos de la CV para proyectos de I+D en cooperaci\u00f3n con empresas 2017, 2018 Y 2019 (IMDEEA/2017/139, IMDEEA/2018/94 y IMDEEA/2019/77) Cada vez m\u00e1s empresas est\u00e1n adoptando soluciones de Big Data Analytics. Actualmente existen herramientas gratuitas y de c\u00f3digo libre, pero la complejidad de las mismas requiere que sean servicios ofrecidos por centros especializados. Durante 2019, el proyecto Radiatus III continua los trabajos iniciados en 2017 y 2018, avanzando en la investigaci\u00f3n, dise\u00f1o y prototipado de servicios el\u00e1sticos de Big Data Analytics (BDAaaS) en la nube sobre la plataforma ECloud - Platform as a Service (PaaS), para el tratamiento de datos en tiempo real (Streaming). El proyecto avanzar\u00e1 en soluciones al gran reto que plantea la complejidad de tratar y analizar grandes cantidades de datos recopilados a trav\u00e9s de diferentes fuentes y adquiridos en tiempo real, el llamado Big Data Streaming Analytics. A trav\u00e9s de estas soluciones las empresas podr\u00e1n centrarse en el an\u00e1lisis de los datos sin perderse en la complejidad de la infraestructura Big Data necesaria para tal fin. Al finalizar el proyecto, se habr\u00e1 creado un servicio de Big Data Streaming Analytics en el ecosistema de Radiatus al servicio de las empresas TIC de la Comunitat Valenciana Primera versi\u00f3n del orquestador de servicios con funcionalidades b\u00e1sicas, para el uso en modo \"multitenant\" del mismo Mejora de la arquitectura y servicios para mejorar su funcionalidad, tolerancia a fallos, rendimiento, seguridad y accesibilidad. Incorporaci\u00f3n de nuevas tecnolog\u00edas Desarrollo de un prototipo de servicio para la plataforma Ecloud , que permita el procesamiento distribuido de modelos de aprendizaje autom\u00e1tico", "label": "poster"}
{"text": "DNA, the genetic blueprint of life, is targeted by a multitude of damaging species of both internal and external origin. This damage can result in the loss of genomic integrity and increase susceptibility to immunodeficiency, neurological disorders, and cancers. Sophisticated DNA repair mechanisms, such as base excision repair, have evolved to correct the damaged DNA and restore genomic integrity. However, errors within these repair mechanisms can result in mutagenic events. Base excision repair, initiates via the use of a DNA glycosylase. Overactivity of alkyladenine glycosylase (AAG), an example of a DNA glycosylase, can result in accumulation of toxic abasic sites that result in mutagenic events and cause cell death. The design and synthesis of a highly active inhibitor of AAG is required. Herein, the rationale behind the design of azanucleoside mimics of such an inhibitor is described, followed by their synthesis. Additionally, development, optimisation, and application of an AAG inhibitory bioassay will provide some of the key structural activity relationships to allow determination of the feasibility of using these inhibitors as therapeutic agents.", "label": "poster"}
{"text": "A major hypoxic blackwater event occurred in 2016 in response to large unregulated flood events in rivers of the southern Murray-Darling Basin. \uf0b7 Caused by extensive overbank floods inundate floodplains where large quan- tities of organic matter (e.g. leaf litter/grass) had accumulated. \uf0b7 Dissolved organic carbon (DOC) is leached from organic matter and a propor- tion of that DOC is consumed by bacteria which, at the same time also con- sume dissolved oxygen (DO). \uf0b7 During the 2016 floods, consumption of DO by bacteria resulted in severe oxygen depletion (hypoxia) in rivers throughout the river system. MMCP Collaboration Factors Contributing to the 2016 hypoxic blackwater event Centre for Freshwater Ecosystems Fact Sheet Management of future events \uf0b7 Identify those areas of the floodplain that are likely to make the greatest contribution to organic matter loads (and hence blackwater). \uf0b7 Implement more regular inundation of those areas to try and reduce organ- ic matter loads on a more regular basis. \uf0b7 Optimize strategies to mitigate impacts on biotic communities (e.g. fish, crayfish). \uf0b7 Providing environmental water at locations that provide refuge. \uf0b7 Timing of environmental water, to provide refuges for biota at appropriate locations in the Murray-Darling Basin. Contact Centre for Freshwater Ecosystems La Trobe University P: + 61 2 6024 9650 E: cfe@latrobe.edu.au W: latrobe.edu.au/freshwater-ecosystems Further information MMCP Collaboration (MMCP) is a project supported by the Joint State Governments and the Murray-Darling Basin Authority to generate and adopt freshwater ecological knowledge through collaboration, to maintain research capability and contribute supporting science to underpin the Basin-Wide Watering Strategy. Full report: doi.org/10.26181/5d199d3ce698a This synthesis paper is a response to a question poised by the Murray-Darling Basin Officials Committee (BOC) in 2017, in relation to a hypoxic blackwater event that occurred in 2016. The objectives of this theme within the MMCP is to help the BOC address specific questions as they arise. These question will have relevance to the on-going management of Basin Assets. Version 2, July 2019 This project is supported through the Murray-Darling Basin Joint Governments Project team Gavin Rees - CSIRO Land & Water, Albury NSW Causes of blackwater", "label": "poster"}
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{"text": "United States Environmental Protection Agency Office of Research and Development -1 0 -9 -8 -7 -6 -5 -4 0 5 0 1 0 0 1 5 0 2 0 0 h N O G - R O C K In h . - Y 2 7 6 3 2 -1 0 -9 -8 -7 -6 -5 -4 -3 0 5 0 1 0 0 1 5 0 2 0 0 A p o p to s is - N o tc h In h . - D A P T % C o n C a s p a s e 3 /7 -G lo % C o n C e llT ite r-G lo -1 0 -9 -8 -7 -6 -5 -4 -3 0 5 0 1 0 0 1 5 0 2 0 0 A p o p to s is - R O C K In h . - Y 2 7 6 3 2 -1 0 -9 -8 -7 -6 -5 -4 -3 0 5 0 1 0 0 1 5 0 2 0 0 A p o p to s is - E R K 1 /2 In h . - S C H 7 7 2 9 8 4 -1 0 -9 -8 -7 -6 -5 -4 -3 0 5 0 1 0 0 1 5 0 2 0 0 A p o p to s is - P K C In h . - B IS -1 BMPR Notch EGFR Wnt PPAR-y COX-2 mTORC PDGFR PKC RHO EP1-4 CREB AKT ETC I EGFR NO-cGMP ROCK Protein HDAC PARP1 ERK/MAPK p38/MAPK hNP1 Apoptosis Active Selective hNP1 Proliferation Active/Cytotoxic h. Neurite Outgrowth Inactive r. Neurite Outgrowth Awaiting Data Cortical Synap. To be tested Network Formation 7 3 4 5 6 8 9 1 2 -1 0 -9 -8 -7 -6 -5 -4 0 5 0 1 0 0 1 5 0 2 0 0 2 5 0 1 5 1 1 6 M K -2 2 0 6 m T O R C In h . -1 0 -9 -8 -7 -6 -5 -4 0 5 0 1 0 0 1 5 0 rN O G - C O X -2 In h . - C e le c o x ib -1 0 -9 -8 -7 -6 -5 -4 0 5 0 1 0 0 1 5 0 rN O G - E R K 1 /2 In h . - S C H 7 7 2 9 8 4 P331 %control %control %control %control %control %control %control %control -1 0 -9 -8 -7 -6 -5 -4 0 5 0 1 0 0 1 5 0 rN O G - A K T A c t. - S C 7 9 \u2022 The DNT battery captures some important and highly conserved signaling pathways associated with various processes involved in neurodevelopment. \u2022 Specifically, we demonstrated that: \u2022 Wnt, mTORC, PKC, and PDGFR pathway modulators have selective effects on neurite outgrowth. \u2022 ERK1/2, AKT, and COX-2 pathway modulators demonstrated non-selective effects on neurite outgrowth. \u2022 To date, ROCK, NO-cGMP, and COX-2 do not seem to play a significant role in our assays. Future Directions: \u2022 Ten chemicals remain to be tested in the battery. \u2022 After all chemicals have been tested, a concentration-response analysis will be performed using the ToxCast pipeline. \u2022 If we find that developmentally relevant biology is not being adequately recapitulated in the battery, we may explore incorporating other assays that include these pathways. Preliminary ToxCast Analysis Discussion References \u2022 These results work in conjunction with the full OECD DNT battery developed in collaboration with global partners. \u2022 Our work expands upon previous in vitro DNT pathway characterizations especially when it comes to neurite outgrowth\u00b9, demonstrating that our battery is sensitive to Wnt, PKC, PDGFR, and mTORC disruption. \u2022 A more robust characterization of the biology captured by our assays will aid in the interpretation of results gathered using the DNT battery. * The views expressed in this poster are those of the author(s) and do not necessarily represent the views or policies of the U.S. Environmental Protection Agency. \u2022 The current NOG data (15 chemicals) has been analyzed using ToxCast R package tcplfit2 (v0.1.6). The computed AC\u2085\u2080 for each chemical and endpoint are given in the figure below. \u2022 The color scale indicates selectivity, which is determined as the ratio between the cytotoxic AC\u2085\u2080 and the AC\u2085\u2080 for the endpoint of interest. \u2022 Eventually, the AC\u2085\u2080 for each chemical and endpoint in the DNT battery will be computed, showing which pathways are best covered by the DNT battery and where improvements are needed. rNOG Neuron count Neurite count per neuron Neurite length per neuron Branch points per neuron DAPT-Notch Inh. ODQ-NO-cGMP Inh. Pioglitazone-HCl PPAR-y IWP2-Wnt Inh. Y-27632 ROCK KG-501-CREB Inh. AG1478-EGFR Inh. Celecoxib-COX-2 Inh. SCH772984-ERK1/2 Inh. SC79-AKT Act. MK-2206-mTORC Inh. CP-673451-PDGFR Inh. MHY1485-mTORC Act. BIS-1/BIM-1-PKC Inh. CHIR99021-Wnt Act. Computed \ud835\udc68\ud835\udc68\ud835\udc68\ud835\udc68\ud835\udfd3\ud835\udfd3\ud835\udfd3\ud835\udfd3 AC\u2085\u2080: Concentration (\u00b5M) at which 50% maximum activity is observed. Endpoint Selectivity Ratio Selective Non-selective 3 1 Conclusions Selectivity Ratio = \ud835\udc34\ud835\udc34\ud835\udc34\ud835\udc3450\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36 \ud835\udc34\ud835\udc34\ud835\udc34\ud835\udc3450\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38\ud835\udc38 \u2265 3, Selective Effect 1. Masjosthusmann", "label": "poster"}
{"text": "Sourajit Dey Department of Agronomy, Bidhan Chandra Krishi Viswavidyalaya, Mohanpur, Nadia, West Bengal - 741252, India. \u201cI wish to double the income of farmers by 2022 when India will celebrate 75 years of its independence.\u201d PM Narendra Modi while addressing farmers rally at Bareilly (Feb 28, 2016) \u201cOver the last seven years, the Government of India has taken many initiatives for transforming agriculture. From better irrigation to more technology, more credit and markets to proper crop insurance, focus on soil health to eliminate middlemen, the efforts are all encompassing.\u201d PM Narendra Modi addressing at the webinar on PM-Kisan\u2019s 2nd anniversary (Feb 23, 2021) Not only the farm incomes (i.e. output or the income of the sector or the value added or GDP of agriculture sector) but also the income of farmers. REAL INCOME not NOMINAL INCOME Nominal income can be defined as the income expressed in monetary terms and measured in current currency (in India its Rupee). Real income can be stated as the income of individuals or nations after adjusting for inflation.Real income = Nominal income \u2013Inflation \uf0fcReduction in arable land. \uf0fcLower crop yields. \uf0fcLow consumption of pesticides leading to increase in pest attack. Fig- 1 Yields of major crops (tons/ha), 2017 Fig 2- Per capita consumption of pesticides (kg/ha), 2016 \uf0fcLack of short duration HYVs. \uf0fcHigher cost of production. \uf0fcImbalance in application of chemical fertilizers. \uf0fcLow Farmers\u2019 Income. \uf0fcLower irrigation efficiency. \uf0fcLow storage and processing facilities. \uf0fcLack of marketing facilities. \uf0fcPrimitive way of farming. \uf0fcA huge marketing margin taken by middlemen. Fig-3 Percentage of Farm households below poverty line \uf0d8Boost Crop productivity through better technology & increased use of quality seed, fertilizer and irrigation and crop-protection chemicals \uf0d8Incentive structure in the form of remunerative prices of some crops and subsidies on farm inputs \uf0d8Public investments in agriculture \uf0d8Building institutions Crudely, increase in area and productivity can be two major options to increase the agricultural output. \uf076Quality seeds (Improving seed replacement rate). \uf076Focus on irrigation along with adequate resource building (\u2018Per Drop More Crop\u2019). \uf076Soil-test based nutrient management (Distribution of soil health cards). \uf076Opting normal sowing (to take the advantage of the weather anomalies). \uf076Pulses as a candidate crop (Pulses in a crop rotation can scale the per unit productivity, diminish the cost of production). \uf076Adopting the recommended package of practices (region specific). \uf076Supplementing soil with micro-nutrients (like Mn, S, Zn and Fe; if deficient). \uf076Use of more bio-fertilizers, vermi-compost and FYM in addition to chemical fertilizers. \uf076Post-harvest crop losses (Large investments in warehousing and cold chains). \uf076Diversification towards high value crops (Introduction, adaptation and acceptance of new varieties as well as new and upcoming production technologies). \uf071Crop protection chemicals are used during both pre-sowing & sowing, post sowing stages of farming. \uf071Food crops must compete with 30,000 species of weeds, 3,000 species of nematodes and 10,000 species of plant-eating insects. We know that despite the use of modern crop protection products 20-40% of potential food production is still lost every year to pests. \uf071To increase crop yields, continuous improvement of agricultural technologies is required to minimize crop losses. INTEGRATED PEST MANAGEMENT (IPM) Prevention:- Prevention can be done through- \uf0a7Location of crops (best suited to climate, soil, topography) \uf0a7Selection of crop variety (choosing beneficial crop varieties) \uf0a7Crop planting and rotation \uf0a7Soil management \uf0a7Water management Monitoring:- Tools like- \uf0a7pheromone traps, diagnostics and forecasting systems can assist in monitoring. \uf0a7Geographic information systems and remote-sensing techniques can also assist in area wide management. Intervention:- Intervention can be done through- \uf0a7Cultural and physical methods \uf0a7Biolo", "label": "poster"}
{"text": "Problem statement Awareness raising seminars Organised by each partner (7 EU Member States), bringing together different stakeholders in the field of migration and child protection Objectives \u2022 Raising awareness of the challenges in the field of international family law, migration and refugee law \u2022 Collecting feedback and best practices Transnational roundtables Organised by Ghent University and one partner (M\u00fcnster, Versailles and Milan) Objectives \u2022 Improving uniformity of procedures applied to migrant children within the EU, including guardianship decisions, child marriage and kafala \u2022 Creating and strengthening sustainable networks between migration law, private international law and (international) family law authorities and organisations in different EU Member States Bookon thechild\u2019s best interest in cross-border civil cases International conference 24-25 June 2024, Brussels Buildingnetworks Collecting empirical data Main objectives Connecting International Family Law and Migration Law Enhancing the Child\u2019s Best Interest in Cross-Border Cases More info: https://famimove.unimib.it/# Belgian partner FAMIMOVE: jinske.verhellen@ugent.be leontine.bruynen@ugent.be geertrui.daem@ugent.be \u25aaDeficits in the protection of children and family relationships in a cross-border context \u25aaMigration and asylum authorities, civil servants, judges, welfare services have too little knowledge of private international law instruments and their coordination with EU- and national migration law", "label": "poster"}
{"text": "Heracleum sosnowskyi Br\u00e2nca ursului Familia Apiaceae, Clasa Magnoliopsida SPECII CU ASPECT SIMILAR Foto & illustration credit: Kus Veenvliet, J., P. Veenvliet, M. de Groot & L. Kutnar (eds.). 2019. A Field Guide to Invasive Alien Species in European Forests. Nova vas: Institute Symbioisis, so. e.; Ljubljana: The Silva Slovenica Publishing Centre,Slovenian Forestry Institute. https://species.biodiversityireland.ie/pro\ufb01le.php?taxonId=187116 Frunze submerse Heracleum mantegazzianum 1-3 m Plant\u0103 bienal\u0103 sau peren\u0103, cu o \u00een\u0103l\u021bime de 100-300 cm. Tulpina este br\u0103zdat\u0103 cu pete purpurii \u0219i cu peri\u0219ori. Frunzele, pe fa\u021ba superioar\u0103 sunt lipsite de peri\u0219ori, iar pe fa\u021ba inferioar\u0103 prezint\u0103 peri\u0219ori \ufb01ni. Marginile frunzelor au din\u021bi scur\u021bi \u0219i rotunji\u021bi. Frunzele inferioare sunt \u00eemp\u0103r\u021bite \u00een trei segmente u\u0219or divizate \u00een p\u0103r\u021bi ovale, scurt ascu\u021bite. Florile sunt albe, uneori rozalii, organizate \u00een umbele compuse, u\u0219or convexe de 30-50 cm. Fructele au form\u0103 oval\u0103, sunt dens p\u0103roase atunci c\u00e2nd nu sunt coapte. Fructele mature sunt aripate, cu numero\u0219i spini situa\u021bi pe mici um\ufb02\u0103turi sferice sau ovoidale Tulpina Fructe Heracleum mantegazzianum se distinge prin dimensiunea sa, \ufb01ind printre cele mai mari plante erbacee din Europa. Poate cre\u0219te p\u00e2n\u0103 la 4-5 m \u00een\u0103l\u021bime. Heracleum persicum are, \u00een general, 1,5-2,5 m \u00een\u0103l\u021bime. \u00cen special frunzele \u0219i semin\u021bele au un miros asem\u0103n\u0103tor anasonului. Heracleum persicum Specie de interes pentru UE", "label": "poster"}
{"text": "LO Feynman diagrams for the canonical single top production modes; a) s-channel, b) t-channel, c) tW. Single top quark production \u2013 Top quarks at the LHC are produced predominantly via QCD with t partner, \u2013 Can be produced singly via EW interactions. Why do we study them? \u2013 Direct probes of Vtb and therefore sensitive to new physics, \u2013 Background to many searches, \u2013 Can constrain PDFs, \u2013 Provides measurements of top quark properties. tW production Latest cross section measurements of the tW process at CMS Duncan Leggat Fudan University, Shanghai Dilepton channel Lepton plus jets channel LP2021 \u2013 January 22 Duncan Leggat (Fudan University) [1] Higher-order corrections for tW production at high-energy hadron colliders, N. Kidonakis and N. Yamanaka, JHEP 05 (2021) 278, arXiv:2102.11300. [2] Observation of associated production of a single top quark and a W boson, CMS Collaboration, arXiv:1401.2942v2. Inclusive cross section Differential cross sections Diagram Removal vs Diagram Subtraction \u2013 tW at NLO interferes with tt and makes simulation difficult, \u2013 DR (default scheme) removes diagrams from signal definition, \u2013 DS (treated as a systematic) subtracts a gauge invariant term. First observation of tW production [2] The associated production of a single top quark with a W boson Major backgrounds \u25cf tt \u2013 shares diagrams with tW at NLO (see below), \u25cf Drell-Yan (dilepton channel), \u25cf QCD and W+jets (lepton + jets channel). Event signature \u25cf2 leptons (muon/electron), \u25cfAssociated MET, \u25cf1 jet from a b quark. Event signature \u25cf1 lepton (muon or electron), \u25cfAssociated MET, \u25cf3 jets, 1 from a b quark. Analysis strategy \u25cf36 fb-1 pp collision data collected in 2016 by CMS at \u221as = 13 TeV, \u25cfData-driven estimation used for QCD background, \u25cfBDT to discriminate between tW and tt background, \u25cfBinned likelihood fit on BDT output to extract tW production cross section. Result Measured cross section: 89 \u00b1 4 (stat) \u00b1 12 (syst) pb First observation of tW in the l+jets channel Leading uncertainties: \u2013 JES, data-driven background estimations, tt simulation SM cross section (aN3LO): 79.5+1.9 -1.8 (scale) +2.0 -1.4 (PDF) [1] Analysis strategy \u25cf36 fb-1 pp collision data collected in 2016 by CMS at \u221as = 13 TeV, \u25cfUsing most sensitive e\u03bc channel, \u25cfBDT to discriminate between tW and tt background in 1j1t and 2j1t regions, \u25cfBinned likelihood fit on BDT output and subleading jet pt in 2j2b region to extract tW production cross section. Measured cross section: 63.1 \u00b1 1.8 (stat) \u00b1 6.4 (syst) \u00b1 2.1 (lumi) pb Leading uncertainties: \u2013 JES/JER, \u2013 Object selection and reconstruction efficiencies, \u2013 tt simulation JHEP10(2018)117 CMS PAS TOP-19-003 - CDS record 2712818 JHEP11(2021)111 A fiducial region is defined enriched in tW signal to extract differential measurements. Selected events pre- and postfit Single top quark cross sections measured by CMS", "label": "poster"}
{"text": "(pronounced nm-archive) is a FAIR and Open,Consensus-Driven Nuclear Magnetic Resonance (NMR) Data Repository and Computational platform. https://nmrxiv.org Journal of Natural Products 2023 \u2013 New NMR Data Requirements recommends NMR data deposition in nmrXiv for new compounds reported in J. Nat. Prod. Articles. nmrXiv: A FAIR and Open, Consensus-Driven NMR Data Repository and Computational Platform V. Nainala, Jena/DE, N. Sharma, Jena/DE, N. Rayya, Jena/DE, S. Kuhn, Tartu/Estonia, J. Liermann Mainz/DE, S. Neumann, Halle/DE, O. Koepler, Hannover/DE, C. Steinbeck, Jena/DE Aims and Objectives Software development To develop a voluntarily FAIR, cloud-based infrastructure that uses freely shared source code and deployment methods. Apply industry-grade development practices to ensure platform reliability, safety, and ef\ufb01cacy. Submission, Curation and Analysis Enable the FAIR Sharing of raw NMR data to enhance the quality of chemical research and dissemination. Also, to develop non-prescriptivist curation and analysis standards for data and metadata. Build standards with input and contributions from the community and make them compatible with existing and potential newly developed formats and approaches. Training To engage analytical chemistry researchers and adjacent communities through webinars, workshops, tutorials, and community calls to ensure that nmrXiv meets the researchers\u2019 needs and implements adequate incentive mechanisms for data contributions and curation. Documentation https://docs.nmrxiv.org Data submissions https://nmrxiv.org Submission Process ~ https://nmrxiv.org Data Backups and RDM FAIR & Open Source Documentation nmrXiv aims to enable the FAIR Sharing of raw NMR data to enhance the quality of chemical research and dissemination. Also, to develop non-prescriptivist curation and analysis standards for data and metadata. Build standards with input and contributions from the community and make them compatible with existing and potential newly developed formats and approaches. NMRium is an open-source NMR spectra visualisation and processing tool and a key integral part of nmrXiv. \u25cfHandles 1D & 2D Spectra. \u25cfSmart Peak Picking. \u25cfSupports various \ufb01le formats such as JCAMP-dx, Bruker and JOEL output and NMRedata. \u25cfHandles molecular structures. \u25cfOpen source - https://nmrium.org nmrXiv data is equipped with robust data backup plan to recover the data in case of disaster. helpdesk@nfdi4chem.de info@nmrxiv.org Data versioning and multi-site disaster recovery ensure data availability and facilitate recovery during server failures, accidental deletions, or security breaches. Why nmrXiv? nmrXiv is the \ufb01rst FAIR and Open archive to preserve NMR data in its original instrument format. It promotes Open Data and Open Standards to maximize the long-term sustainability of the resource and the FAIRness of the archived data. Over the past few decades, several repositories have been developed to host literature-derived and experimental NMR data; however, these repositories do not meet the needs of all chemical communities (also natural products & metabolomics) in several ways. This includes a lack of experimental data, limited search capabilities, and more importantly, they are not FAIR compliant. SmartLab Repos 4Chem Ontologies 4Chem Community 4Chem Legal 4Chem Standards 4Chem Editors 4Chem RAW FILES PROCESSED FILES ~ STANDARD FORMATS LONG TERM ARCHIVAL Version 3.0 Version 2.0 Version 1.0 WEB API AI/ML tools CASE SEARCH ENGINES STEP 1: FILE UPLOAD ARCHIVAL / PUBLISHING STEP 2: ASSIGNMENTS & META-DATA STEP 3: VALIDATION nmrXiv follows a documentation-\ufb01rst approach that allows developers & users to discuss proposed features and ensure that the implementations reflect the real use cases. DOCS: https://docs.nmrxiv.org Advanced Spectra Analysis Demo https://dev.nmrxiv.org Code repository https://github.com/NFDI4Che m/nmrxiv Submission steps* STEP 1: FILE UPLOAD STEP 2: ASSIGNMENT & META-DATA STEP 3: VALIDATION Drag and drop your raw \ufb01les and", "label": "poster"}
{"text": "COLOUR, LIPID AND PROTEIN OXIDATION IN BREAST AND THIGH MEAT OF BROILERS RAISED IN FOUR PRODUCTION SYSTEMS IN BELGIUM Zeshan Ali*, Eline Kowalski and Stefaan De Smet Laboratory for Animal Nutrition and Animal Product Quality, Department of Animal Sciences and Aquatic Ecology, Ghent University, Belgium *Corresponding author email: Zeshan.Ali@ugent.be I. INTRODUCTION Worldwide, broilers are raised in different production systems from extensive to intensive, covering a range of genetics and management practices. Influence of the production system on the oxidative stability of meat has not been widely studied [1]. Oxidation of myoglobin, lipids and protein are major causes of quality deterioration in meat [2]. Differences in in vivo and postmortem muscle metabolism may affect the endogenous antioxidant defense system and the release of pro-oxidants and reactive oxygen species, resulting in potential differences in resistance against oxidation. The main objective of the present study was to compare oxidation in breast and thigh meat from broilers produced in four divergent production systems in Belgium. II. MATERIALS AND METHODS In this study, 4 broiler production systems with distinctive characteristics (Intensive, Better Chicken Commitment (BCC), Slow growth with outdoor access and Organic) were selected (Table 1). From each production system, 5 farms randomly distributed in the country were chosen, and 15 broilers (mixed sex; 3 broilers per farm) were slaughtered and sampled. On day 2 after slaughter, the meat from the thigh and breast muscles (skinless) was minced and approximately 40 g was placed in petri dishes. These petri dishes were covered with a foil to limit dehydration and exposed to light (1600-2200 lux) for 7 days in the fridge at 2-4 \u00b0C. Colour lightness (L*), redness (a*), and yellowness (b*) were measured daily in duplicate with a Hunterlab Miniscan colour meter (D65 light source, 10\u00b0 standard observer, 45\u00b0/0\u00b0 geometry, 1-inch light surface, white standard) to estimate colour stability. The difference (day1 \u2013 day7) in colour lightness (\u0394L), redness (\u0394a), yellowness (\u0394b) and total colour difference \u0394E (\u0394E = [(\u0394L)2 + (\u0394a)2 + (\u0394b)2]1/2) was calculated for this purpose. On day 7, the samples were vacuum packed and frozen at -80\u00b0C for analysis of lipid and protein oxidation. Lipid oxidation was assessed in duplicate, spectrophotometrically by the thiobarbituric acid reactive substances (TBARS) method based on Tarladgis et al. [3] and expressed as malondialdehyde (MDA) in \u00b5g per g meat. Protein oxidation was measured in duplicate through the formation of protein carbonyls compounds (PCC), according to the method of Oliver et al. [4] with some modifications by Ganhao et al. [5]. PCC were determined spectrophotometrically, following their covalent reaction with 2,4- dinitrophenylhydrazine (2,4-DNPH), and expressed in nmol carbonyls per mg protein. Table 1 Summary of production characteristics This data was summarized from 18 farms sampled so far (Intensive, Slow growth and Organic n=5 each, and BCC n=3) *Outdoor access was temporarily not possible due to avian flu. Intensive BCC Slow growth Organic Breed Ross 308 RedBroM Ja 757 Ruby XL (SASSO) Age at slaughter (days) 39-42 42-45 56 73-76 Live weight at slaughter (kg) 2.6-2.8 2.4-2.6 2.1-2.3 2.3-2.5 Stocking density (kg/m2) 42 30 27-33 21 Outdoor access No No Yes (limited)* Yes*", "label": "poster"}
{"text": "Measuring coastal upwelling using IMOS Himawari-8 and Multi-Sensor SST Helen Beggs, Christopher Griffin, Gary Brassington and Pallavi Govekar Bureau of Meteorology, Melbourne, Victoria, Australia Contact: helen.beggs@bom.gov.au www.imos.org.au IMOS is a national collaborative research infrastructure, supported by Australian Government. It is led by University of Tasmania in partnership with the Australian marine and climate science community. 8. Acknowledgements We acknowledge the provision of raw AVHRR data from ground-stations operated by the Bureau of Meteorology, Australian Institute of Marine Science, Western Australian Satellite Technology Applications Consortium, Geosciences Australia and Commonwealth Scientific and Industrial Research Organisation (CSIRO).We also acknowledge the provision of NPP VIIRS SSTskin retrievals from the National Oceanic and Atmospheric Administration (NOAA) and the provision of the Himawari-8 AHI L1b data from the Japanese Meteorological Agency (JMA) and Japanese Space Agency (JAXA). 1. Introduction The Australian Bureau of Meteorology (BoM) have since 24th March 2016 produced operational, real-time, sea surface temperatures (SST) from the Himawari-8 geostationary satellite every 10 minutes at ~2 km spatial resolution (at nadir) on the native satellite (\"GEO\") projection. For ease of use, and to reduce spatial data gaps due to cloud, these native resolution SST data have been composited to hourly and daily night-only mean SST files, projected onto the rectangular Integrated Marine Observing System (IMOS) grid at 0.02o x 0.02o. The compositing of the Himawari-8 data on the IMOS grid presents opportunities for use alongside operational IMOS \"Multi-Sensor\" SST products incorporating data from the Visible Infrared Imaging Radiometer Suite (VIIRS) and Advanced Very High-Resolution Radiometer (AVHRR) satellite sensors, to identify coastal upwelling events. The aim of this study is to determine if these new IMOS satellite products can be used to verify the efficacy of the Bureau's operational version 3.1 Ocean Modelling, Analysis and Prediction System (OceanMAPS) 10 km resolution model (BoM, 2017) in resolving and predicting coastal upwelling around the Australian coast. To assist the study, we also compare with an experimental Ensemble Optimal Interpolation (EnOI) 10 km resolution SST analysis (\"GSAS\") of the same satellite SST data assimilated into OceanMAPS, using the same Sakov (2014) assimilation system. 4. Coastal upwelling case studies \u2022 Himawari-8 Level 2 Pre-processed (L2P) SSTskin is produced by training Himawari- 8 brightness temperatures to NOAA's ACSPO Suomi-NPP VIIRS L2P bias corrected SSTsubskin on a single day in 2015, followed by subtracting 0.17oC \u2022 Quality level (QL) is derived for each SST value based on proximity to cloud, identified using GEOCAT method (http://cimss.ssec.wisc.edu/csppgeo/geocat.html), and size of estimated error, estimated on \"local brightness temperature variability\u201d \u2022 Possible quality levels are 0 to 5, with 5 identifying highest quality \u2022 10 minute Himawari-8 L2P SSTs are composited to hourly Level 3 Collated (L3C) SST by selecting best quality, spatially and temporally consistent value \u2022 Hourly SSTs are composited to daily, night-time L3C SST by selecting best quality value, closest in time to local sunrise \u2022 Hourly or daily L3C data on GEO projection are mapped to IMOS 0.02o x 0.02o grid using sub-pixel area-weighted averaging of any overlapping pixels (Fig 1a-b) \u2022 Night-time Himawari-8 L3C QL \u2265 4 SST from 1 Nov 2017 to 30 Apr 2019 over IMOS domain biased -0.4oC with 0.9oC standard deviation compared with collocated drifting and tropical moored buoys (BoM fv01 SST Validation Web Page) \u2022 Himawari-8 L3C netCDF files from 1st October 2017 to present available on request 5. Conclusions We compared night-time 2 km composites of Himawari-8 and Multi-Sensor (AVHRR and VIIRS) SST data at ~0.2 m depth with the BoM operational OceanMAPS v3.1 SST analyses and forecast", "label": "poster"}
{"text": "DATA ANALYSIS WITH TOPIC MODELS FOR COMMUNICATIONS RESEARCHERS FREDERICK BOEHM (FRED.BOEHM@WISC.EDU), DEPARTMENT OF STATISTICS, UNIVERSITY OF WISCONSIN-MADISON ABSTRACT We introduce topic modeling as a tool when analyzing textual data. We illustrate our methods with analyses of New York Times transcripts and tweets from three days in March 2016. We argue that such analyses will be useful in mass communications and journalism research. These methods are especially useful for identifying topics, or themes, in large collections of texts, when reading each piece individually is impractical. INTRODUCTION Social media users \ufb02ood us with tweets, status updates, and blog posts. Data analysis with topic models enable re- searchers to identify themes, or topics, in a collection of texts. We present results from separate analyses of 1) New York Times articles from March 19, 20, and 21, 2016 and 2) a collection of tweets (from Twitter) from the same three days. Our manuscript contains computing code to repro- duce our \ufb01ndings. REFERENCES [1] David M Blei. Build, compute, critique, repeat: Data analysis with latent variable models. Annual Review of Statistics and Its Applica- tion, 1:203\u2013232, 2014. METHODS 1. Fit latent Dirichlet allocation (LDA) models, sepa- rately, to 1) our collection of tweets and 2) our collec- tion of print media articles from the New York Times 2. Visualized the topic modeling results with word clouds 3. Assessed resulting topics for coherence RESULTS video music march song tonight live justin check listen album fly show reaction love night pm ft day bieber watch playlist nowplaying fans radio star today added movie official priceless book la playing np soundcloud stage drake dj de years rihanna house tour young talks feat batman coming band list Figure 1: Word cloud for one topic (from a 20-topic model) of tweets from March 19, 20, and 21, 2016. game city win league season man team leicester today goal points fans united play good back football mufc rashford manchester time half top games state st great year goals player lead players chelsea point penalty west basketball years won marchmadness match derby day big iowa demichelis final premier home live Figure 2: Word cloud for one topic (from a 20-topic model) of tweets from March 19, 20, and 21, 2016. music show film theater production movie song songs musical work director played dance ballet company album play movies set performance life role stage york star country broadway story williams band opera character festival love series sound altman works record shows orchestra plays films center season drama bowie concert dancing singer Figure 3: Word cloud for one topic (from a 20-topic model) of New York Times articles from March 19, 20, and 21, 2016. water baalsrud island men ship arctic boat ships cruise islands expedition sea kelen miles ocean small feet river franklin genz inuit crew story found trip hawaii cruises north food wind norwegian di head escape baalsruds huth snow open pacific frozen joel haug local van coast william lake deck cabin canoe Figure 4: Word cloud for one topic (from a 20-topic model) of New York Times articles from March 19, 20, and 21, 2016. DISCUSSION From the word clouds above, and those not shown, we \ufb01nd differences between the topics of discussion on Twitter and the topics in the New York Times. For instance, we \ufb01nd in the tweets an entire topic that deals with sports (with an emphasis on soccer) and another topic that involves music and entertainment. The New York Times analysis yields topics that match many of the newspaper sections. The two topics above might be called \"Music\" and \"Travel & Adventure\".", "label": "poster"}
{"text": "The BDF format was created based on EDF, but BDF supports 24-bit resolution. In this sense, if there is a need to convert a BDF file to a more widely used format such as the EDF, there may be loss of information. The GDF format allows several other formats to be converted to it without loss [7]. EDF yielded the best compression capability, and the GDF occupies the largest disk space. The XML-based formats (ecgML, HL7, OpenXDF) follow a pattern in which there is a hierarchical structure with attributes addressing the characteristics and configurations of the file, unlike the others, whose information is based on a sequence of data controlled by the positioning of the characters. It would be interesting to have a tool capable of providing information to manufacturers, developers, researchers of these formats, to keep their information and the characteristics updated, helping thus, future researches, problem corrections and better implementations. ACKNOWLEDGEMENTS REFERENCES DISCUSSION AND CONCLUSION 1Aluno p\u00f3s-gradua\u00e7\u00e3o, Faculdade de Engenharia El\u00e9trica, Universidade Federal de Uberl\u00e2ndia - jpfolador@gmail.com INTRODUCTION The primary purpose of biomedical data acquisition is monitoring, diagnosis or research, and its recording depends on these goals [1]. Thus, monitoring of vital signs in a surgery requires immediate analysis and visualization, whereas data collection for research or diagnosis needs to store the data in the first place, dispensing real- time visualization [2]. These biomedical signals can be continuously measured in different ways depending on the underlying physiological phenomenon responsible for its generation. In any approach related to biomedical signal collection it is necessary to verify memory occupancy and the quality of stored information for avoiding data loss [1][2] A large amount of biomedical data is generated by the recording of time varying signals from different parts of the body, for instance, the electroencephalogram (EEG), electrocardiogram (ECG), electromyogram (EMG), electrooculogram (EOG) and inertial activity. In this context, over the years the medical industry and research consortiums have been addressing the issue of establishing the most suitable data format for the storage of biomedical time-series [3]. The search for standardization and its adoption can reduce costs, optimize joint work, and increase the quality of research results [4]. The first objective of this work was to identify the most used types of file formats employed for storage of time-series resulting from biomedical data. The second purpose was to compare distinct file formats by verifying data compression rates and suitability. MATERIALS AND METHODS In order to understand the file formats used in the recording of biomedical signals and their context today, some questions were raised: \u2022 What are the file formats used to collect biomedical signals? \u2022 What are the features and information available in these formats? \u2022 Is there a file format that is widely used and supports different biomedical signals? \u2022 Do commonly used files take up a lot of storage space? [1] Bronzino J. D. Medical Devices and Systems: The Biomedical Engineering Handbook, 3rd ed. CRC Press, Hartford, Connecticut, U.S.A (2006). [2] Penzel, T., Acquisition of biomedical signals databases. IEEE Eng Med Biol Mag 20:25\u201332. (2001). [3] Rubel, P., SCP: ECG V3.0: An enhanced Standard Communication Protocol for computer:assisted Electrocardiography. In: Computing in Cardiology Conference (CinC), 1\u20134 (2016). [4] V\u00e4rri, A., Kemp, B., Penzel, T., Schl\u00f6gl, A. Standards for biomedical signal databases. IEEE Eng Med Biol Mag 20:33\u201337 (2001). [5] Institute of Science and Technology: Scientific data formats. http://pub.ist.ac.at/~schloegl/matla b/eeg/. last accessed 2018/01/30. [6] Kemp, B., Olivan, J. European data format \u201cplus\u201d (EDF+), an EDF alike standard format for the exchange of physiological data. Clin Neurophysiol 114:1755\u20131761. (2003). [7] Schl\u00f6gl, A. GDF ", "label": "poster"}
{"text": "SPECTROSCOPIC ANALYSIS OF OB STARS IN THE CARINA NEBULA Simone Da\ufb02on 1, Wilton Santos 1,2, Jo\u00e3o Victor Sales Silva 1, and the Gaia-ESO Survey Team 1Observat\u00f3rio Nacional 2UESC Introduction Massive OB stars are luminous and young objects, being easily observed and located close to their place of birth, allowing the mapping of the present-day abundances of the Galaxy. OB stars are generally found in OB associations, one of them is Car OB, a large, very active star-forming region in the Carina- Sagittarius spiral arm. Its stellar population is split into several open clusters associated with the Carina Nebula. In this work, we present a detailed spectroscopic study for a sample of OB stars located in 8 open clusters in the Carina Nebula: Trumpler 14, Trumpler 15, Trumpler 16E/W, Collinder 228, Collinder 232, Bochum 11 and NGC 3293. Data This study is based on high-resolution spectra obtained with the FLAMES/GIRAFFE spectrograph coupled to the UT2 VLT 8 m telescope, in the context of the Gaia-ESO Public Spectroscopic Survey. The GIRAFFE con\ufb01gurations are optimized to detect important features in the spectra of early-type stars such as H\u03b3 line, an important log g-indicator and some important lines for Teff diagnosis, as for example, C iii, O ii, Si iii, and Si iv lines. Projected rotational velocity We obtained the projected rotation velocity V sin i for a sample of 330 OB stars, probable members of 8 open clusters in the Carina Nebula, based on a calibration for the widths of two He i lines, at \u03bb 4388 and 4471\u00c5[2]. The V sin i distribution for the full sample represented by the blue histogram (Fig 1) is consistent with typical V sin i distributions for open clusters while the V sin i distributions for \ufb01eld OB stars tend to peak at lower V sin i. Fig 2 presents the violin distributions for the 5 clusters of our sample with more than 40 studied stars: the average V sin i for individual clusters varies between 126\u00b177 km s\u22121, for Collinder 228, and 180\u00b184 km s\u22121, for NGC 3293. Stellar Parameters and Abundances We use a semi-automatic routine based on non-NLTE model atmospheres and synthetic spectra (TLUSTY/SYNPLOT) [1, 3] to perform a self-consistent analysis and determine the atmospheric parameters Teff, log g, V sin i, microturbulence and macroturbulence, as well as abundances of Silicon, Oxygen, Carbon and Nitrogen, for a subsample of 65 sharp-lined stars. The e\ufb00ective temperature has been de\ufb01ned from the ionization balance between Si ii, Si iii, and Si iv (Fig 3), while log g has been derived from the \ufb01ts of H wings (Fig 4). Results The stars in our sample are mainly on the main sequence, with Teff between 14,000 and 33,000 K and log g between 3.00 and 4.50 (Fig 5). In Fig 6 we present the violin distributions for the abundances of studied species. The average abundances of C, N, and O are consistent with the solar value while being slightly subsolar for Si. Our results suggest that the Carina Nebula is chemically homogeneous to within \u223c 0.10 dex and the average abundances of O and Si are consistent with its radial position in the Galactic disk (Fig 7), as expected by [1]. References [1]G. A. Bragan\u00e7a, S. Da\ufb02on, and et al. A&A, 625:A120, 2019. [2]S. Da\ufb02on, K. Cunha, F. X. de Ara\u00fajo, S. Wol\ufb00, and N. Przybilla. The Astronomical Journal, 134:1570\u20131578, 2007. [3]I. Hubeny and T. Lanz. arXiv:1706.01859, 2017. Acknowledgements W.S acknowledges \ufb01nancial support from CAPES and FAPERJ for Ph.D. fellowships. S.D. acknowledges CNPq/MCTI for grant 306859/2022-0.", "label": "poster"}
{"text": "Tau Neutrino Appearance with 8 Years of IceCube Neutrino Data \u00c9tienne Bourbeau, for the IceCube Collaboration Niels Bohr Institute etienne.bourbeau@icecube.wisc.edu References [1] S. Parke, M. Ross-Lonergan. Phys. Rev. D, 93, 113009 (2016) [arXiv:1508.05095] [2] Aartsen et al (IceCube Collaboration). JINST 12 P03012 (2017) [arXiv: 1612.05093] [3] Aartsen et al (IceCube Collaboration). Phys. Rev. D, 99 032007 (2019) [4] A. Fedynitch. Matrix Cascade Equation. https://github.com/afedynitch/MCEq [5] G.D. Barr et al. Phy. Rev. D, 74, 094009 (2006) [arXiv: astro-ph/0611266] The IceCube and DeepCore Detectors Neutrino Oscillations in IceCube Unitarity \u2022 Significance based on likelihood Test Statistic : \ud835\udc48!\" \ud835\udc48!# \ud835\udc48!$ \ud835\udc48%\" \ud835\udc48%# \ud835\udc48%$ \ud835\udc48&\" \ud835\udc48&# \ud835\udc48&$ + + \u00b2 \u00b2 \u00b2 = 1 + + \u00b2 \u00b2 = 1 Analysis Principle Digital Optical Module (DOM) \u2022 30 cm photomultiplier tube + digitizer encapsulated in a pressure vessel \u2022 Designed to detect Cherenkov radiation from particle interactions in the ice \u2022 Elementary unit of the detector 0 m 1450 m 2450 m IceCube Neutrino Observatory [2] \u2022 Deployed to detect neutrinos of astrophysical origin \u2022 Consists of 86 strings of sensors buried underneath the South Pole The DeepCore Sub-Array \u2022 8 strings of high quantum efficiency DOMs \u2022 10 Mton fiducial volume \u2022 ~ 500 sensors in closer spacing \u2022 Rest of IceCube is used as a veto region Systematics Uncertainties: Analysis treats uncertainties as nuisance parameters in the fit: \u2022 Neutrinos and muon spectral index \u2022 Atmospheric Neutrino Flux ([4], [5]) \u2022 Quasielastic and resonant form factor \u2022 Deep Inelastic scattering cross section \u2022 Earth Model (neutrino propagation) \u2022 Dom Efficiency \u2022 Refrozen ice parametrisation \u2022 Bulk Ice absorption & scattering Reconstruction of neutrino events \u2022 Charge and time of hits from all DOMs are fed into a likelihood-based event reconstruction algorithm \u2022 \ud835\udf4a\ud835\udf41,\ud835\udc6a\ud835\udc6ainteractions have mostly track- like profiles, while \ud835\udf4a\ud835\udc86,\ud835\udc6a\ud835\udc6a, \ud835\udf4a\ud835\udf49,\ud835\udc6a\ud835\udc6aand all \ud835\udf4a\ud835\udc75\ud835\udc6ainteractions produce point-like (ie cascade) profiles \u2022 Neutrino oscillations constitute the only experimental evidence of non- conformity to the Standard Model (potential evidence for new physics) \u2022 It describes transitions between flavor states to mass states Sensitivity Projections Event Selection Production (as \ud835\udf4a\ud835\udf41\u2018s) Propagation (as superpositions of \ud835\udf4a\ud835\udfcf\u2018s, \ud835\udf4a\ud835\udfd0 ) \ud835\udc2cand \ud835\udf4a\ud835\udfd1\u2019s) Detection (as \ud835\udf4a\ud835\udc86\u2018s, \ud835\udf4a\ud835\udf41) \ud835\udc2cand \ud835\udf4a\ud835\udf49\u2019s) \u2022 PMNS unitarity constraints are weakest for the third generation of neutrinos, an area where IceCube is highly sensitive [3] \u2022 Non-unitarity could indicate that the 3x3 PMNS matrix is a subset of a larger N x N mixing matrix \u2022 IceCube operates in energy ranges were \ud835\udf42\ud835\udf49,\ud835\udc6a\ud835\udc6across- section is much less kinematically suppressed than in accelerator experiments \u2022 We count the number of neutrinos detected per particle ID (ie flavor), energy and zenith bins \u2022 We then compare the result to our expectations from standard oscillation \u2022 Tau neutrino fraction is fit as a statistical excess of events in non-track events (ie we don\u2019t identify individual tau neutrino events) Cascade-Like Events Mixed Events Track-Like Events Neutrinos from cosmic-ray interactions in the atmosphere are reconstructed with associated energy and direction (proxy for distance travelled). They allow IceCube to cover a wide range of oscillation baselines (~10 to 10000 km, and 5 to 300 GeV) \u2022 We perform a multi-dimensional fit of a Monte-Carlo template to our data. The fit includes both physical (\ud835\udf1f\ud835\udc8e\ud835\udfd1\ud835\udfd0 \ud835\udfd0, \ud835\udf3d\ud835\udfd0\ud835\udfd1, tau normalization \ud835\udc75\ud835\udf49) and nuisance parameters to handle systematics. \u2022 Ratio of a scenario with \ud835\udc75\ud835\udf49= 0.5 w.r.t standard oscillation paradigm \u22122 \ud835\udc3f\ud835\udc3f\ud835\udc3b+,-./01. \ud835\udc3f\ud835\udc3f\ud835\udc3b2!34 The Sample in Numbers \u2022 Consists of eight years of detector data (mid-2011 to mid-2019) \u2022 Several cuts applied to eliminate atmospheric muons and self-triggered noise events (our main backgrounds) \u2022 Use of new machine-learning classifiers (boosted decision trees) to perform final- level muon rejection + PID classification \u2022 Yields a large statistics sample of neutrinos that well suited for \ud835\udf4a\ud835\udf41disapp", "label": "poster"}
{"text": "Opening mathematical Astronomy by Searching for Orbital Constant that Hidden in variable star cylinder on earth ID 89 1, 2.Department of physics, Dambi Dollo University,Dambi Dollo,Ehiopia Abstract The study of astronomy is needed to integrate variable star with mathematics and science education. In this study we examined the cylinder constant hidden in the formula of the volume of any circular cylinder. Volume of the cylinder(V)= r2h.V= .This Study and digging out the mystery part of a cylindrical coordinate system needed to understand the origin and the nature of celestial (Astronomical) coordinate system that allows Oromo Educators to calculate Oromo Calendar and register it on UNESCO. Keywords:cylinder,height,diameter,circumference, volume, variable constant. 2.Introduction In the history of science, physical science in the geometry, optics, mechanics and astronomy compiled and allowed scientists to develop Physics.This work focused to open the variable star physics experiment in the geometry. Variable stars talk to human kind through their variability. As explained in Serway (2004), Archimedes was the first to compute accurately the ratio of a circle\u2019s circumference to its diameter. 3. Research Question: Can we find a hidden \"cylindrical constant\" related to variable cylindrical materials 4.Methods: Measurements were taken using local and cultural materials like variable rings, Rope, Qubeelaa Ce'umsaa Figure1.Variablering&Qubeelaa Ce'umsaa 5.Result and Discussion During the variable constant training for every one we have measured the following data is using variable ring. Table 1 No C D 1 51 16.2 The average value of \u03c0 = = = 3.148 % error = x100%= 0.164% Table 2 .The variable data of the experiment Qubeelaa Ce\u2019umsaa No C D \u03c0 1 125.9 40 3.1475 2 126.1 40.1 3.14463804 3 126 40. 3.15 4 126.1 40.1 3.14463804 5 126 40 3.15 \u03a0average= =3.147355376 %of error = = 0.1432697% If the percentage error is very small (in variable ring) 0.164% our achievement is 99.836% true. The percentage error of Qubeelaa Ce\u2019umsaa 0.1433% our achievement is 99.867% true. The materials which we use called variable ring and Qubeelaa Ce\u2019umsaa the percentage error is very small which means our experimental error is nearly to the constant or \u03c0. \u03c0 is one of the cylinder constant on the cylindrical objects on the earth. The ratio of volume of cylinder to the product of its circumference, Diameter and height which yield us constant . show the = V = r 2 h ,Since r= ,V= 2 H .Divide both sides for CDH, = Therefore 0.25 is the numerical value of cylinder constant or cylinder geometric pattern. 6.Conclusion We discovered that the origin of \u03c0 is not solely confined to circular objects, but also extends to ellipses.. The result suggest that the ratio of the volume of a cylinder to the product of its circumference, Diameter, and height is a hidden mathematical constant whose value equal to 0.25.These findings, presented at IAUGA2024, shed light on previously overlooked aspects of physics and geometry. Our work at Dambi Dollo University aims to innovate the study of variable star physics within the context of ancient geometry,contributing the advancement of modern astronomy and sharing our discoveries with the IAU community. 7 .References 1.A text Book of Analytical Geometry of Three Dimensions, by P.K. Jain and Khaleel Ahmed, Published by Wiley Eastern Ltd., 1999.Khaleel Ahmed, Published by Wiley Eastern Ltd., 1999 .2.A text book of Mathematics for BA/B.ScVol 1, by VKrishna Murthy & Others, Published by S. Chand & Company, New Delhi. Delhi.3Archimedes' Secret, transcript ofhe BBC television program Horizon broadcast 14 March 2002;", "label": "poster"}
{"text": "Barium daughter tagging using single molecule \ufb02uorescence imaging Austin D McDonald, Fernanda Psihas For the NEXT Collaboration Currently, the only known method to determine the Majorana nature of the neutrino is a direct observation of neutrinoless double beta decay. The NEXT experiment employs a series of high-pressure xenon gas TCPs with energy resolution of ~0.7% FWHM at the Q value. The gas phase allows for accurate track reconstruc- tion. Sensitivity to the topology allows for discrimination between back- ground and signal. The theoretical spectrum for the two neutri- no and no neutrino spectrums. 2D diagram of the NEXT detector. Example of NEXT-new data events. The difference between signal and background are the large depositions at the end of electron tracks (two for signal). N N P P e \u2013 e \u2013 N N P P e \u2013 e \u2013 \u03bd\u2013 \u03bd\u2013 Ton-scale neutrinoless double beta decay (0\u03bd\u03b2\u03b2) experiments expect only a few events per year. Radioactive backgrounds in the form of alpha, beta, and gamma decays can mimic the double electron signal. Barium is not produced by any of the backgrounds to \u03b2\u03b2 decay. Edan Bainglass, Frank Foss, Ben Jones, David Nygren, Pawan Thapa Exploiting a bio-chemistry technique to enhance sensitivity to \u03b2\u03b2 decay !\"#$%&'&\"() !\"#$%&'()*+,-)- *%+(#,-.$/'&\"() ./01 ./01 We employ \ufb02uorescent dyes to do Single Molecule Fluorescent Imaging (SMFI). The dye molecule con- sists of a \ufb02uorophore, which naturally de-excites via \ufb02uoresence, and a receptor, which quenches the \ufb02uorescence. The dye molecules are non-\ufb02uorescent in the ab- sence of ions. When bound to an ion, the energy levels for \ufb02uorescent de-excitation become avail- able. The receptor may be ion speci\ufb01c and can be coupled to different dyes. Development of a dye for use in high pressure xenon gas is currently underway, in collabora- tion with the department of chemistry at UTA. This custom dye is based on PSMA, a molecule know to have high sensitivity to Ba++, and a good candidate for use in xenon gas. Our SMFI implementation may also allow for super-resolution reconstruction, since it local- izes molecule positions to within a few nm. FLUOROPHORE RECEPTOR O O O Cl O Cl HO CH3 N N CO2H CO2H CO2H CO2H FLUOROPHORE RECEPTOR O O O Cl CH3 O O O N N O O O O O O Cl HO Baa++ Total Internal Re\ufb02ection Fluorescence (TIRF) utilizes evanescent wave excitation to excite the molecules that are a few wavelengths away from the surface. Left: Dye molecule used in our \ufb01rst demonstration of single molecule barium sensitivity. Top: Un-chelated molecule (not \ufb02uorescent). Bottom: Molecule chelated to Ba++ ion (\ufb02uorescent). Right: Single molecule imaging setup at UTA. The 498 nm excitation light is delivered by a colimated laser, focused on the objective\u2019s backfocal plane. The \ufb02uores- cence emmision is collected by the CCD. The objective is used to convert the focused laser light into parallel rays at the critical angle. Single barium di-cation sensitivity has been achieved utilizing the method of Single Molecule Fluorescent Imaging (SMFI) described above. Solutions are made with a speci\ufb01c pH, and diluted to small ion concentration. Trace ions are then removed with a chelation agent. The molecules are immoblized for imaging by trap- ping them in a matrix. Typical TIRF image, showing single molecules located at various depths in the sample. Pixel sixe is 160 nm. The dye\u2019s \ufb02uorescence is diffraction limited, this allows for super-resolution reconstruction which localizes the molecule to ~2nm . TIRF was used to image near the surface and minimize \ufb02uorescence from deep in the sample by means of evanescent wave excitation. Single barium ion \ufb02uorescent tra- jectory, demonstrating the abrupt single step photobleaching. The analysis of barium rich vs no barium samples showed a signal over back- ground at the 12.9 sigma level. Single molecules are identi\ufb01ed by the characteristic photobleaching process, where the molecule transitions to a non-\ufb02uorescent state in one step. First demonstration of single Ba++ i", "label": "poster"}
{"text": "Services OPERAS versteht sich als verteilte euro\u00adp\u00e4ische Forschungs\u00ad infrastruktur, die die offene Wissenschaftskommunikation in den Geistes- und Sozial\u00adwissenschaften unterst\u00fctzt. OPERAS-GER ist ein Projekt zur Ver\u00adnet\u00adzung von OPERAS in der deutschen Wissenschafts\u00adlandschaft. Kontakt https://operas-ger.hypotheses.org/ www.operas-eu.org @OPERAS_GER Zertifizierungs- service Entwickelt im Projekt: Metrics-/Altmetrics Service Entwickelt im Projekt: Discovery Service (GOTRIPLE) Entwickelt im Projekt: Research for Society Service Entwickelt im Projekt: Weitere Services sind in Planung Publishing Service Portal Entwickelt im Projekt: \u00dcber 50 Organisationen aus mehr als 15 L\u00e4ndern National Nodes - als Kontakt- und Verkn\u00fcpfungsstelle au\u00dferhalb OPERAS - zur Verkn\u00fcpfung nationaler Infrastruktur mit der europ\u00e4ischen Ebene zust\u00e4ndig f\u00fcr - die Einbindung neuer Mitglieder in die OPERAS Community - den Kontakt zu Forschenden und Akteuren im Bereich Open Access - sowie die Vernetzung mit (potentiellen) Geldgebern Ziele 1. Bekanntheit in der deutschen Wissenschaftslandschaft steigern 2. Zielgerichtet Infrastruktur- und Forschungseinrichtungen, Institutionen, Bibliotheken etc. kontaktieren und einbinden 3. Services pr\u00e4sentieren und Workshops organisieren, um die Bedarfe der deutschen Forschungslandschaft zu sammeln & zu verstehen Poster und Pr\u00e4sentation: Larissa Saar (Max Weber Stiftung/ OPERAS-GER)", "label": "poster"}
{"text": "Hochschule f\u00fcr Gesundheit \u00b7 University of Applied Sciences \u00b7 Gesundheitscampus 8 \u00b7 44801 Bochum alina.napetschnig@hs-gesundheit.de Hintergrund und Ziele Methodik Ergebnisse und Diskussion Die Entwicklung des G\u00fctekriterienkernsets f\u00fcr senior*innengerechte VR-Anwendungen beruht auf einem mehrschrittigen, multimetho- dischen Studiendesign. Die Definitionen und Inhalte der jeweiligen Anforderungen der Kriterien werden in einem iterativen Prozess entwickelt (vgl. Abb. 1). Der Vorgang orientiert sich an dem \u201ePlan, Do, Check, Act\u201c-Kreis (PDCA) und beschreibt vier Aufgaben, die sich zyklisch im Sinne der laufenden Verbesserung wiederholen3. In den einzelnen Teilschritten werden qualitative Forschungsmethoden, wie die Framework Analyse, Gruppendiskussionen sowie Aspekte der Grounded Theory angewendet. Die aufgestellten Kriterien des vorl\u00e4ufigen G\u00fctekriterienkernsets werden anhand einer VR-Trainingsanwendung zur Stra\u00dfen\u00fcber- querung mit Senior*innen zielgruppengerecht und partizipativ in einer Interventionsstudie mit anschlie\u00dfender Gruppendiskussion evaluiert. Die abschlie\u00dfenden Ergebnisse stellen das evaluierte standardisierte G\u00fctekriterienkernset dar. Literatur 1) Baas, J. (2020). Digitale Gesundheit in Europa. Berlin: Medizinisch wissenschaftliche Verlagsgesellschaft. 2) Deiters, W., H\u00f6cker, P., Napetschnig, A. & Preissner, L. (2022). Innovationsr\u00e4ume f\u00fcr die partizipative Entwicklung digitaler nutzer*innenzentrierter Anwendungen. In: Department of Community Health (Hrsg.): Community Health - Grundlagen Methoden, Praxis; Weinheim Basel, Beltz Juventa, S. 411 - 423 3) Sch\u00f6nsleben, P. (2016). Integrales Logistikmanagement: Operations und Supply Chain Management innerhalb des Unternehmens und unternehmens\u00fcbergreifend. Berlin: Springer-Verlag. Die aktuellen Ergebnisse beziehen sich auf den dritten PDCA-Zyklus und bilden das vorl\u00e4ufige G\u00fctekriterienkernset zu den Kategorien: Die Kriterien bilden die Grundlage f\u00fcr die Entwicklung der VR- Trainingsanwendung (vgl. Abb. 2) und k\u00f6nnen detailliert durch Scannen des QR-Codes eingesehen werden. Die Resultate stellen erste Erfordernisse zu VR-Gestaltungsanforderungen dar. Abbildung 1: Implementierung des PDCA-Kreises in den Produktentstehungsprozess (PEP) zur Entwicklung des G\u00fctekriterienkernsets Quelle: Eigene Darstellung Abbildung 2: Screenshot VR-Trainingsanwendung f\u00fcr Senior*innen zur sicheren Stra\u00dfen\u00fcberquerung Quelle: Eigene Darstellung Virtual Reality (VR) ist nicht nur in der Spieleindustrie vertreten, zunehmend etabliert sich diese innovative Technologie im Gesund- heitssektor1. Ein Leitfaden, der essentielle G\u00fctekriterien f\u00fcr die Entwicklung von VR-Anwendungen f\u00fcr Senior*innen enth\u00e4lt, existiert bisher nicht. Lediglich bestehen allgemeing\u00fcltige Kriterien f\u00fcr digitale Gesundheitswendungen, die weder zielgruppenspezifisch sind, noch eine Eingrenzung der Technologien beinhalten2. \u2022 \u2022 \u2022 Definition und Evaluierung Anforderungskriterien f\u00fcr den Einsatz von VR in der Gerontologie Problemstellung Bewertung bestehender allgemeing\u00fcltiger Kriterien f\u00fcr digitale Gesundheitsanwendungen Ergebnis Partizipativ-evaluiertes G\u00fctekriterienkernset mit g\u00fcltigen Kriterien f\u00fcr senior*innengerechte VR-Anwendungen Take Care 09./10. M\u00e4rz 2023 Hauptforschungsfrage: Welche Anforderungen muss eine Gesundheitsanwendung in VR f\u00fcr den Einsatz in der Gerontologie erf\u00fcllen? Nutzer*innenorientierte Gestaltung und Bewertung von Virtual Reality-Anwendungen f\u00fcr Senior*innen Alina Napetschnig (M.A.) Allgemeine Anforderungen (I) VR-spezifische Anforderungen (II) 1. Qualit\u00e4tssicherung med./ gesundheitlicher Inhalte 1. Grafik/ Qualit\u00e4t 2. Datenschutzbestimmungen 2. 3D-Charakter/ Avatar 3. Qualit\u00e4tsanforderungen 3. Bereitstellen von spielinternen Anweisungen und Aufforderungen 4. Verbraucherschutz 4. Interaktion 5. Interoperabilit\u00e4t 5. Navigation 6. F\u00f6rderung der Nutzermotivation und Nutzungstreue WEGFEST. \u2013 SCAN ME!", "label": "poster"}
{"text": "https://www.researchobject.org/ro- crate/community.html info@elixir-belgium.org RO-Crate Toolbox Higher level interfaces for interacting with RO-Crates RO-Crate is a generic packaging format containing datasets and their description using standards for FAIR Linked Data. The format is based on schema.org annotations in JSON-LD, which allows for rich metadata representation of (data-) artifacts as external references when necessary. The format has been implemented in a wide range of services such as WorkflowHub and Galaxy. ro-crate-py The core RO-Crate Python library: ro-crate-py (https://pypi.org/project/rocrate/) provides a high-level interface to create, load and manipulate RO- Crate objects. The core library is in the process of being wrapped in different platforms such as Galaxy tools and other GUI environments. Workflow Run RO-Crate We are co- developing Workflow Run RO-Crate profile to store workflow execution data and metadata, including prospective and retrospective provenance, as well as associated tooling for its generation. from rocrate.model.person import Person alice_id = \"https://orcid.org/0000-0000-0000-0000\" bob_id = \"https://orcid.org/0000-0000-0000-0001\" alice = crate.add(Person(crate, alice_id, properties={ \"name\": \"Alice Doe\", \"affiliation\": \"University of Flatland\" })) bob = crate.add(Person(crate, bob_id, properties={ \"name\": \"Bob Doe\", \"affiliation\": \"University of Flatland\" })) RO-Crate in Galaxy We have integrated RO-Crate in Galaxy, using ro-crate-py, to allow for the export of RO-Crates. Galaxy can now, for example, generate a Workflow Run RO-Crate from a workflow run and provide it for export by processing the Galaxy workflow definition and - execution details.", "label": "poster"}
{"text": "\uf0a7 Stoichiometric ratios of 1:1, 1:2, 1:3, 2:1 and 3:1 of Febuxostat and the coformer (probenecid, adipic acid and \u03b1-ketoglutaric acid) respectively, were subjected to a liquid assisted grinding (LAG) approach, with the drop wise addition of acetonitrile (25\u00b5L) in a mortar and pestle. \uf0a7 The ground mixture was then dried in an oven at 80 \u00baC for 2 hours. Post drying, it was transferred into a dry container and kept in the desiccator. \uf0a7 The solid-state characterization of FXT and its eutectic systems was carried out using a differential scanning calorimeter (DSC) and powder X-ray diffraction (PXRD). The DSC results were in turn used to construct the binary phase diagram (BPD) for each system. \uf0a7 pH dependent solubility studies were carried out at 25 \u00baC using the shake flask method over a pH range of 4-10 using different buffered solutions. \uf0a7 And the micro-environmental pH studies were performed using the slurry method. Poster No. 21M1200 Febuxostat Eutectics: lost moieties in the quest for Co-crystals Moksh Jagia1, Ruchi Daptardar1, Kinjal R Patel1, Sameer Modi2, Pawan Kumar Singh2, Arvind Kumar Bansal2, Sarsvatkumar Patel1 1Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, NY 2National Institute of Pharmaceutical Education and Research (NIPER), India PURPOSE METHOD RESULTS & DISCUSSION Screening, preparation and characterization of eutectic systems of the drug Febuxostat (FXT), using thermal and analytical techniques, with the initial goal of screening for co- crystals. CONCLUSION REFERENCE \uf0a7 DSC indicated towards the formation of eutectic systems by the presence of an invariant low melting endotherm in each case. \uf0a7 PXRD confirmed the systems as eutectic with combination peaks of drug and coformer \uf0a7 The presence of an acidic micro-environment imparted by the coformers resulted in a substantial loss of eutectic system solubility. \uf0a7 Further cocrystallization studies with better coformer selection strategy for the weakly acidic FXT drug needs to be carried out. \uf0a7 S. Cherukuvada, A Nangia, \u201cEutectics as improved pharmaceutical materials: design, properties and characterization,\u201d Chem. Commun. 2014, 50, 906. \uf0a7 Badawy, Sherif I. Farag, and Munir A. Hussain. \"Microenvironmental pH modulation in solid dosage forms.\" Journal of pharmaceutical sciences 96.5 (2007): 948-959. \uf0a7 A single invariant low melting point (solidus) in all molar compositions is the characteristic of the eutectic phase. \uf0a7 While a small variable liquidus point manifests for the near- eutectic or non-eutectic compositions \uf0a7 A typical BPD of a eutectic assumes a \u2018U\u201d or \u2018V\u2019 shape, with the point lacking the liquidus peak representing the pure eutectic phase. \uf0a7 While the BPD of a co-crystal assumes a \u2018W\u2019 shape. 160 170 180 190 200 210 220 160 170 180 190 200 210 220 0 0.25 0.5 0.75 1 Temperature (\u00b0C) Mole Fraction of FXT Solidus Peak Liquidus Peak FXT PROB FXT:PROB Eutectic 130 140 150 160 170 180 190 200 210 220 130 140 150 160 170 180 190 200 210 220 0 0.25 0.5 0.75 1 Temperature (\u00b0C) Mole Fraction of FXT Solidus Peak Liquidus Peak FXT ADP FXT:ADP Eutectic 90 110 130 150 170 190 210 90 110 130 150 170 190 210 0 0.25 0.5 0.75 1 Temperature (\u00b0C) Mole Fraction of FXT Solidus peak Liquidus peak FXT a-KETO FXT: a-KETO Eutectic 0 2000 4000 6000 8000 10000 12000 14000 4.01 5.63 8.21 10.13 Solubility (\u00b5g/mL) pH FXT Drug FXT:Probenecid (1-1) Eutectic FXT:Adipic acid (1-3) Eutectic FXT:a-Ketoglutaric acid (1-3) Eutectic The invariant endotherm for FXT:PROB system appeared around 174\u00baC, with the single phase melting transition (1-1 ratio) at 175.23 \u00baC representing the pure eutectic phase. The BPD exhibited a \u2018U\u2019 shape characteristic for eutectic formation. The invariant endotherm for FXT:ADP system appeared around 149\u00baC, with the single phase melting transition (1-3 ratio) at 150.23\u00baC representing the pure eutectic phase. The BPD exhibited a \u2018V\u2019 shape characteristic for eutectic formation. The invariant endotherm for FXT: a-Keto system appear", "label": "poster"}
{"text": "Project Sherlock Generating better leads for criminal investigations Technologies Big Data Analytics Volume: Criminal cases can involve many terabytes of data. Velocity: The search for clues is often time-bound by circumstances as well as by law. Variety: Storage devices can contain a great variety of file types, and the layout of individual files is not known beforehand. distributed computing The task of analyzing a storage device breaks down into many smaller tasks, which need to be distributed over the available hardware resources. hardware accelerators Photos and videos can be analyzed much more quickly using dedicated hardware such as GPUs. image analysis Computer vision methods allow for automatically annotating photos and videos with metadata such as the names of people, places, and weapons. data management A dedicated data management solution makes the data searchable, and enables feeding selections of data to visualization tools. Digital storage devices such as harddisks, mobile phones, and USB drives are increasingly common in criminal cases. Extracting viable leads from such a device poses various technological challenges. The Netherlands eScience Center is helping the Netherlands Forensic Institute face these challenges by extending their toolchain with a number of eScience technologies. visualization Interactive visualizations provide insight into the course of events. natural language processing More and better clues are produced more quickly using techniques that extract meaning from textual data. Video Mobile phone Photo Person Camera Camera Location Credit card transaction Mobile phone Person Mobile phone Photo Photo Photo Photo Storage devices Camera Video Video", "label": "poster"}
{"text": "IRPPS E-PUBLISHING SERVICE: PERFORMANCE ASSESSMENT AND DEVELOPMENT OF FUTURE SERVICES Roberta Ruggieri, Fabrizio Pecoraro, Marianna Nobile, Rosa Di Cesare National Research Council, Institute for Research on Population and Social Policies, Rome, Italy \u2022 Irpps library supports Open Access (OA) promoting digital scholarship as an alternative channel to diffuse niche products in Humanities and Social Sciences \u2022 In 2012 Irpps launched \u201cCnr-Irpps e-Publishing\u201d, a service to manage internal editorial products based on Open Journal System (OJS). The software was customized to support the research needs of its community \u2022 Two series are published: Monographs and Working Papers (WPs) \u2022 Contents & submission: guideline for the submission and for the management of final editing \u2022 Peer review: internal peer review of the WP series, external peer review for Monographs \u2022 Copyright & licensing: creative commons, version 3.0. Free access for all contents \u2022 Access & preservation: persistent identifier and long-term preservation in Solar - CNR institutional repository Improvements \u2022 Quality of abstract \u2022 Complete metadata \u2022 Accuracy of cited references Background Background \u2022 Upgrading to OJS 3.0 with additional functionalities implemented (Altmetrics) \u2022 Digitization of previously published works that represent important achievements of IRPPS research results \u2022 Development of a data repository linked to IRPPS publications to increase the replicability and reusability of research in Social Sciences \u2022 Improvement of the practices and infrastructures to support data sharing and citations Publication workflow Publication workflow Continuity \u2026..and changes to improve quality and quantity of IRPPS publications Continuity \u2026..and changes to improve quality and quantity of IRPPS publications Further enhancements Further enhancements Policies Policies This work is licensed under a Creative Commons Attribution 4.0 International License. Roberta Ruggieri: r.ruggieri@irpps.cnr.it Editorial quality Editorial review and technical editing, that occur before publication in two phases: pre- and post-acceptance Scientific quality Peer review process Improvements \u2022 Relevance \u2022 Usefulness \u2022 Methodological and ethical soundness of research Library catalogue: 118 WPs + 12 Monographs 2012 1981 Page views in 2011: around 5000 2018 Cnr-Irpps e-Publishing service: 100 WPs + 10 Monographs Page views: 2013-2018 around 110000, 16000 users Page views: 2017 around 11000, 3000 users 29 WPs cited 151 citations 70000 downloads 85000 views", "label": "poster"}
{"text": "A WLS Re\ufb02ector, made of copper-tetratex foil, surrounds the LAr instrumenta6on and the HPGe detector strings: Eur.Phys.J.C 82 (2022) 5, 442 CIEMAT Leibniz Inst. for Polymer Research South Dakota Mines Univ. of North Carolina at Chapel Hill Comenius Univ. Los Alamos Natl. Lab. Tech. Univ. Dresden Univ. of Padova and INFN Czech Tech. Univ. Prague and IEAP Max Planck Inst. for Nucl. Phy. Tech. Univ. Munich Univ. of Regina Daresbury Lab. Max Planck Inst. for Physics Tennessee Tech. Univ. Univ. of South Carolina Duke Univ. and TUNL Natl. Res. Center Kurchatov Inst. Univ. of California and LBNL Univ. of South Dakota Gran Sasso Science Inst. Natl. Res. Nucl. Univ. MEPhI Univ. College London Univ. of Tennessee Indiana Univ. Bloomington North Carolina State Univ. Univ. of L'Aquila and INFN Univ. of Texas at Austin Inst. Nucl. Res. Rus. Acad. Sci. Oak Ridge Natl. Lab. Univ. of Cagliari and INFN Univ. of Tuebingen Jagiellonian Univ. Polytech. Univ. of Milan Univ. of California San Diego Univ. of Warwick Joint Inst. for Nucl. Res. Princeton Univ. Univ. of Houston Univ. of Washington and CENPA Joint Res. Centre Geel Queen's Univ. Univ. of Liverpool Univ. of Zurich Lab. Naz. Gran Sasso Roma Tre Univ. and INFN Univ. of Milan and INFN Williams College Lancaster Univ. Simon Fraser Univ. Univ. of Milano Bicocca and INFN Leibniz Inst. for Crystal Growth SNOLAB Univ. of New Mexico 40K 4- 1.15 Gyr 0+ Q\u03b2 = 1.5 MeV Stable 89% 40Ca EC 11% 1461 keV 11% 0+ 40Ar Stable zoom 42Ar 0+ 32.9 yr Q\u03b2 = 599 keV 2- 42K 12.355 h Q\u03b2 = 3.5 MeV 0+ 2+ 0+ 82% 18% 0.34% 42Ca 313 keV 1525 keV Stable 2. LAr Scin+lla+on o 1 \u03bcm TetraPhenyl Butadiene (TPB) surface coating by evaporation; o 58 SiPM channels: 58 x 9 Ketek PMT33100T 3x3 mm2 SiPMs. 1. LAr Instrumenta+on Setup The LAr scintillation light emission is superposition of two excimer states (Ar! \u2217), which both decay producing 128 nm Vacuum-Ultra-Violet (VUV) light 5. Performance in LEGEND-200 LEGEND-200 experiment for neutrinoless double beta decay search, using HPGe detectors immersed in LAr cryostat To op6mize the LAr instrumenta6on performance the LAr was puri\ufb01ed from N2, O2 and H2O. PoS PANIC2021 (2022) 102 q The LAr quality is monitored con6nuously by the LEGEND LAr Monitoring Apparatus (LLAMA). EPJ Web Conf. 253 (2021) 11014 Liquid Argon Instrumenta2on for Background Suppression in LEGEND-200 Experiment 1500 mm Gabriela Araujo1, Laura Baudis1, Nina Burlac2,*, Valerio D\u2019Andrea2, Rosanna Deckert3, Maria Fomina4, Konstan6n Gusev3,4, Patrick Krause3, Alexey Lubashevskiy4, Francesco Paissan2, Laszlo Papp3, Nadya Rumyantseva3,4, Giuseppe Salamanna2, Stefan Sch\u00f6nert3, Mario Schwarz3, Egor Shevchik4, Diego Tagnani2, Daniya Zinatulina4 for the LEGEND collaboraVon 1Universit\u00e4t Z\u00fcrich, Switzerland 2Rome Tre University and INFN Roma Tre, Italy *currently at Laboratori Nazionali del Gran Sasso (LNGS) of INFN, Italy 3Technische Universit\u00e4t M\u00fcnchen, Germany 4Joint InsHtute for Nuclear Research, Dubna, Russia q TPB shi]s the VUV light to blue (420 nm); q WLS \ufb01bers shi] the blue light into green (490 nm); q The green light is read out by SiPMS (440 nm). \ud835\udf0ffast= 30 ns q Event Topology Classi\ufb01er (ETC) parameter o ra6o of the light emided in the single component to the total light intensity of an event (N = Ns+Nt): ETC = \ud835\udc0d\ud835\udc2c \ud835\udc0d \ud835\udf0fslow= 8 \u03bcs RiseHme 48 ns q The 9 SiPMs are read out in parallel and di\ufb00erenVally by the front-end electronics. q Overall noise level of 250 \u03bcV (peak-to-peak) and RMS = 58 \u03bcV (mean value). JINST 18 (2023) 09 q Charge and Vme reconstrucVon performed with two independent methods based on rising edge of the trace and di\ufb00ering in the signal \ufb01ltering: o HyperCurrent algorithm \u2013 a Gaussian \ufb01lter is applied to smooth the electronic noise: 95% charge reconstrucVon e\ufb03ciency. o DPLMS \ufb01lter-based algorithm Eur.Phys.J.C 83 (2023) 2 \u2013 an op6mum \ufb01lter is synthe6zed and applied to SiPMs traces: 96% charge reconstrucVon e\ufb03ciency. LAr veto condi1on: q Test staVsVc-based classi\ufb01er that categorizes events as true (TC) or random co", "label": "poster"}
{"text": "NEED HELP? Designing and Implementing the RITMARE Help Desk to Support Research Data Management Zilioli M.1, Lanucara S1., Oggioni A.1 and Carrara P.1 1National Research Council of Italy, Institute for Electromagnetic Sensing of Environment ISSUES \u2022 RITMARE SDI sustainability depends on its data population \u2022 RITMARE Data flows differ according to the research groups\u2019 data management practices \u2022 Research groups have different data management practices according to disciplinary domains and to data management competences of their members (about informatics, data policy, data sharing) \u2022 Different research groups need differential support in order to distribute geospatial data through RITMARE SDI Nodes FRAMEWORK \u2022 RITMARE Project involves a Community of research groups working on different marine issues and belonging to different thematic areas \u2022 RITMARE Spatial Data Infrastructure (SDI) is built to assure interoperability among geospatial data produced by the different research groups \u2022 RITMARE Data flow from the OGC services made available by the distributed nodes of RITMARE SDI, which are either built on purpose during RITMARE or in other projects (External Nodes) \u2022 Interoperability is obtained by exploiting OGC standards; data are made accessible through the RITMARE Data Portal, an OGC compliant web client DESIGNING THE RITMARE HELP DESK \u2022 Survey the RITMARE Community to identify the different data management practices \u2022 Identify different levels of data management competences inside the RITMARE Community thanks to contacts between research groups and RITMARE Data Team \u2022 Identify the Helpdesk activities to support research groups according to their data management competences \u2022 Identify facility tools and service types to enable research groups to acquire new data management competences in order to distribute geospatial data through RITMARE SDI Nodes IMPLEMENTING THE RITMARE HELP DESK \u2022 Identify a webplatform to provide facilities to RITMARE Community \u2022 Estabilish the RITMARE Data Team to create contents and provide assistance through a single contact point RESULTS \u2022 20% of new RITMARE SDI Nodes \u2022 32% of new Data Resources distributed through RITMARE Data Portal \u2022 15% of target research groups attended every webinar session CHALLENGES \u2022 To define a workflow to engage scientists in data sharing \u2022 To manage different use-cases \u2022 To manage different raw data formats RITMARE Data Node RITMARE Data Portal RITMARE SDI Node External Data Node RITMARE Research Groups Data Management Practices Data Management Enablement RITMARE SDI Nodes GLOSSARY \u202245 items \u2022Contents related to collection, format, organization, storage, web distribution, access of geospatial data and their metadata FAQ \u2022 24 items \u2022 Contents: RITMARE Data Portal, RITMARE Data Nodes, RITMARE Data Policy TECHNOLOGICAL services EDUCATIONAL facilities Supporting Learning Training LEVEL 0 Not GIS enabled Geospatial data collection and storage via spreadsheets or texts without georeference LEVEL 1 GIS enabled Data storage without distribution LEVEL 2 GIS enabled WebGIS distribution LEVEL 3 GIS enabled Geoservice distribution via interoperable OGC standard services, metadata aware DATA MANAGEMENT COMPETENCE LEVELS GLOSSARY GLOSSARY Data Transfer to RITMARE Data Nodes INSTRUCTIONS/ VIDEO TUTORIAL Installing and assisting new RITMARE Data Nodes Data Connection to RITMARE Data Nodes WEBINAR HELP DESK SUPPORT ACTIVITIES WEBINAR WEBINAR \u2022 2 items \u2022 Contents: (I) RITMARE SDI: what is it? Policy and Technological Components; (II) How to create own RITMARE Data Node: GET-IT software suite INSTRUCTIONS / VIDEO TUTORIAL \u2022 Contents: How to create own RITMARE Data Node: GET-IT software suite REFERENCES \u2022 GET-IT software suite \u2022 RITMARE Data Portal (v0.0) ACKNOWLEDGEMENTS The activities described in this poster have been funded by the Italian Flagship Project RITMARE http://www.ritmare.it/ This work is licensed under a Creative Commons attribution 4.0 http://creativecommons.org/licenses/by/4", "label": "poster"}
{"text": "The Keystone Women of British and Irish Botany 1856 to 1932 The network of British and Irish Botanists created from herbari- um specimens digitised on Herbaria@home. Each dot represents a botanist, each line represents a connection between the bota- nists. These links between people are that they either collected together, swapped specimens or determined each others speci- mens. Botanists with only one connection have been filtered out to improve readability and also highlight the most connected botanists. The network has been partitioned into 9 modularity classes to give a rough indication of community structure. Fur- ther details can be found in Groom et al. (2014). Only Woman botanists have been named in order to show how well integrated they were into the network of botanists at the time. The network has been laid out using a Fruchterman Riengold algorithm using Gephi 0.8.2 (Bastian et al., 2009) Bastian M., Heymann S., Jacomy M. (2009). Gephi: an open source software for exploring and manipulating networks. Internation- al AAAI Conference on Weblogs and Social Media. Groom QJ, O\u2019Reilly C & Humphrey T (2014). Herbarium specimens reveal the exchange network of British and Irish botanists, 1856\u2013 1932. New Journal of Botany. 4(2) 95-103. Quentin Groom", "label": "poster"}
{"text": "Mar\u00eda J. \u00c1lvarez-P\u00e9rez, Carlos A. Padilla-Jaramillo, B.Sc., Luis M. D\u00edaz-S\u00e1nchez, M.Sc., Marianny Y. Combaiza, PhD., Cristian Blanco-Tirado, PhD., and Aldo F. Combariza, PhD. 1. Departamento de Biolog\u00eda, Universidad de Sucre, Sincelejo, 700001, Colombia. 2. Escuela de Qu\u00edmica, Universidad Industrial de Santander, Bucaramanga, 680002, Bucaramanga, Colombia. S w e e t e n i n g t h e c h e m i s t r y w o r l d w i t h s p r i n k l e s o f q u a n t u m b i o l o g y Proton and Cation Affinities of Biosignature phytoplankton pigments and MALDI matrices from RI-MP2 quantum calculations Phytoplankton is a bioindicator useful to measure environmental health. Pigment-Biosignature compounds detection for these organisms by MALDI MS, allows its chemotaxonomic identi\ufb01cation. Feasible MALDI matrices with thermochemical features (Proton/Cation Affinities -PA/CA- and Ionization Energies -Ei-) guarantees a satisfactory ionization process. So, to establish these properties is a topical issue. We used quantum chemical methods (HF and Pos-HF) to calculate PA/CA energies of MALDI matrices and biosignature pigments. \u24c4 \u24cb \u24ba \u24c7 \u24cb \u24be \u24ba \u24cc Geometry Optimization Aquatic Ecosystem Vibrational Frequency Electrostatic Maps MALDI MS and Proton/Cation matrices L\u00f6wding Charge Analysis \u03b4+ \u03b4- Acknowledgments \u25cfUniversidad Nacional de San Agust\u00edn (UNSA), Arequipa, Per\u00fa for providing access to INKARI cluster facilitis, located at the Observatorio Astron\u00f3mica Pedro Paulet. \u25cfThanks to Guatiguara Technology Park and the Central Research Laboratory Facility at Industrial University of Santander for infrastructural support. \u25cfWe also acknowledge a graduate fellowship and \ufb01nancial support from SGR- BPIN: 2019000100020 and VIE-UIS project 2815 - 2021. Conclusions Geometry Setup protocol is feasible for our systems, and IR spectra are in agreement with experimental reports. From MEP it would be ideal to perform a L\u00f6wding population analysis for determining the protonation sites and associated charge. Next step is to optimize and calculate the SPE to build cation-structures. References \u25cf Denis, Elizabeth H.2022, et al. Proton Affinity Values of Fentanyl and Fentanyl Analogues Pertinent to Ambient Ionization and Detection. Journal of the American Society for Mass \u25cf Padilla Jaramillo, C.A., D\u00edaz S\u00e1nchez, L.M. , Combariza Monta\u00f1ez, M.Y. , Blanco Tirado, C. y Combariza Monta\u00f1ez, A.F. 2021. Photon Harvesting Molecules: Ionization Potential from Quantum Chemical Calculations of Phytoplanktonic Pigments for MALDI-MS Analysis. Orinoquia. 25, 1 (jun. 2021), 13\u201323. DOI:https://doi.org/10.22579/20112629.676. \u25cf Gross, H. J., 2017. Mass Spectrometry.Third Edition. ISBN 978-3-319-54397-0. Springer International Publishing.DOI 10.1007/978-3-319-54398-7 Optimization Method: RI-MP2 Basis set: Def2-TZVP ETol: 1E-08 a.u. MEP maps Method: RI-MP2 Basis set: Def2-SVP IsoValue: 0.004 PS: Protonation Site PS PS PS -0.167 -0.037 -0.052 -0.058 \ud835\udefc-CHCA \ud835\udefc-CHCA Method: RI-MP2 Basis set: Def2-TZVP Grapher: XMGRACE Avoiding negative frequencies and comparing the IR spectral The overlapped experimental and calculated IR have good agreement Proton Enthalpy Reaction Zero Point Energy Protonated - Ground Electronic Energy Protonated - Ground Gas Constant Absolute Temperature PS ID: Phys50", "label": "poster"}
{"text": "A photometric study of the ULLYSES/PENELLOPE T Tauri star sample in Ori OB1 and \ud835\uded4Ori: the accretion process at the highest time resolution The ULLYSES/PENELLOPE project on YSO accretion \u2022 A legacy spectroscopy survey of accreting pre-main sequence stars, including ~70 T Tauri stars \u2022 Synchronized HST COS/STIS as well as VLT UVES/ ESPRESSO/X-Shooter observing campaigns; for a few sources multiepoch observations \u2022 ULLYSES (Roman-Duval et al. 2020): accretion and ejection tracers at ultraviolet/optical wavelengths; ODYSSEUS (Espaillat et al. 2022): archive research to model and interpret the HST spectral observations; PENELLOPE (Manara et al. 2021): stellar parame- ters; interstellar extinction, veiling; disk wind and jets; \u2022 Unique and contemporaneous UV, optical, and near- infrared legacy dataset of a large YSO sample, covering all evolutionary stages from full disk to transitional disks and Class III disk-less objects The Orion sample \u2022 10 stars in Ori OB1, 3 stars in \u03c3 Ori \u2022 Sp. type: K6-M3.5, Mass: 0.25-1.1 M\u2299 \u2022 Distance ~400 pc \u2022 CVSO 17, CVSO 36, CVSO 58, CVSO 90, CVSO 104, CVSO 107, CVSO 109, CVSO 146, CVSO 165, CVSO 176, SO 518, SO 583, SO 1153 \u2022 ULYSSES/PENELLOPE papers: Manara et al. (2021, survey presentation), Frasca et al. (2021, CVSO104), Espaillat et al. (2022, CVSO109), Froebrich et al. (2022, \u03c3 Ori), Pittman et al. (submitted, Ori OB1) \u2022 Our goals: (1) extend the project in the time domain; (2) put the spectroscopic results into variability context; (3) identify the underlying physical processes Accretion rates estimated from optical photometry \u2022 The X-Shooter UV-optical-infrared spectra were fitted with a model composed of a stellar photospheric template and a slab of gas to simulate the accretion hot spot (Manara et al. 2021) \u2022 Adopting stellar and extinction parameters from the X-Shooter model, slab models were fitted to optical broad-band photometry from Konkoly Observatory. We assigned chi2-based probability to each fit, and determined the most likely accretion rate value and its uncertainty at each epoch (left figure) Typical accretion rates: ~10-8 M\u2299/yr; variation \u2a853 Variability timescales \u2022 The observed timescales of variability are related to the physical processes causing the flux changes \u2022 Accretion rate (left) and TESS magnitude (right) differences vs. \u0394t between any two measurements: \u2022 Variability amplitudes steadily increase up to ~2 days, and level off afterward Probably related to rotational timescales Hot accretion spots, funnel flows Does this pattern changes on yearly timescales? References Cody et al., AJ 147, id.82 (2014); De et al., PASP 132, id.025001 (2020); Espaillat et al., AJ 163, id.114 (2022); Frasca et al., A&A 656, id.A138 (2021); Froebrich et al., MNRAS 510, 2883 (2022); Manara et al., A&A 650, id.A196 (2021); Roman-Duval et al., RNAAS 4, id.205 (2020) Acknowledgement This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme under grant agreement No 716155 (SACCRED). Observations \u2022 BVr\u2019i\u2019 images from Konkoly Observatory, Hungary, 2020 Nov 5 \u2013 Dec 26 \u2022 BVRCICz\u2019 images from OACt, Catania, Italy, 2020 Nov 25 \u2013 Dec 16 \u2022 BVr\u2019i\u2019 images, AAVSOnet, 2020 Nov 8 \u2013 Dec 19 \u2022 J-band images, GATTINI survey (De et al. 2020), 2020 Oct 29 \u2013 Jan 2 \u2022 g-band photometry, ASAS-SN survey \u2022 TESS white light (~i-band), 2020 Nov 20 \u2013 Dec 16, 10-min cadence TESS (credit: NASA) Characterization of the light curves Left: Example multi-wavelength light curves of CVSO 146. Middle: Distribution of the T Tauri stars in the QM parameter space (based on Cody et al. 2014) \u2022 Variability amplitudes: typically \u0394V=0.3-0.7 mag, up to 2 mag. Usually decrease with wavelength \u2022 Two-parameter description (Cody et al. 2014): degree of periodicity (Q) and flux asymmetry (M), computed from the TESS light curves \u2022 QM distribution: three light curves are periodic or quasi- periodic, the remaining ones are close to aperiodic \u2022 Most light curv", "label": "poster"}
{"text": "Predic'on of an'bio'c resistance from genomic data using machine learning and deep learning approaches Valen&n Laroche, Edithe Selwa, Bogdan I. Iorga Ins$tut de Chimie des Substances Naturelles, CNRS UPR 2301, Universite\u0301 Paris-Saclay, Gif-sur-YveDe, France bogdan.iorga@cnrs.fr We propose a very efficient knowledge-based approach for input data encoding or dataset enrichment to overcome the intrinsic limitations (small amount of experimental sample, imbalanced datasets) encountered with the use of genomic and biomedical data in machine learning or deep learning predictive models. The KNOTE package for unbalanced dataset enrichment is freely available at the URL: hJps://github.com/IorgaLab/KNOTE Conclusion Introduction This work was supported in part by the Laboratory of Excellence in Research on Medication and Innovative Therapeutics (LERMIT) [grant number ANR-10-LABX-33], by the JPIAMR transnational project DesInMBL [grant number ANR-14-JAMR-0002] and by the R\u00e9gion Ile-de- France (DIM MALINF). Acknowledgements Results Three di\ufb00erent encoding modes of genomic data, each one with its advantages and limita'ons, were used for the prepara'on of input datasets. The performance of several machine learning and deep learning approaches was evaluated using these datasets. The best performance was obtained with Convolu'onal Neural Network approach and knowledge-based dataset encoding. However, a clear limita'on was the unequal distribu'on of classes leading The availability of increasing amounts of genomic and biomedical data makes machine learning and deep learning the methods of choice for the prediction of antibiotic resistance, a worldwide health problem of utmost importance. However, several strong limitations have hampered the development of this field. to imbalanced datasets. The dataset enrichment performed with publicly available soaware (SMOTE, ROSE) provided only liJle improvement in the predic'on accuracy, due to errors introduced during enrichment. In these condi'ons, we have developed a new tool called KNOTE (KNowledge-based Oversampling TEchnique) for the error-free enrichment of imbalanced data from genomic and biomedical studies, to be used in machine learning or deep learning predic'ons. The use of KNOTE- enriched datasets provided up to 95-98% accuracy in the predic'on of an'bio'c resistance. 1. Kos, V.N.; D\u00e9raspe, M.; McLaughlin, R.E.; Whiteaker, J.D.; Roy, P.H.; Alm, R.A.; Corbeil, J.; Gardner, H. \"The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibility\" Antimicrob. Agents Chemother. 2015, 59, 427-436. Reference Materials and methods Input datasets were prepared from 390 genomes of Pseudomonas aeruginosa with known minimum inhibitory concentra'on (MIC) values for 4 an'bio'cs [1], using three approaches: knowledge-based (output of ResMiner, a bacterial genome analysis tool developed in our group), n- grams and k-mers. Data availability", "label": "poster"}
{"text": "Laura Bader, Marie-Christine Ramel, Toby G. R. Andrews, Kirti Gupta, Jennifer Pearson-Farr, Lucy M. Collinson and Rashmi Priya Summary Nuclear lobularity increases with cardiac forces in ventricle but not in atrium. How the nucleus, one of the stiffest organelles inside a cell, sustains and responds to mechanical forces in vivo remains understudied. The developing zebrafish vertebrate heart is a unique model system to address this fundamental problem as it generates and withstands substantial mechanical forces. Using in toto imaging, 3D morphometrics, genetics, pharmacological perturbations and scRNA-seq, our work reveals that the two heart chambers, ventricle and atrium, have strikingly distinct cardiomyocyte nuclear morphologies, possibly correlating with Lamin A/C expression and microtubule localisation. Manipulation of cardiac forces and knockdown of Lamin A/C affects only ventricle nuclear morphology while microtubule manipulation affects nuclear morphology in both chambers. Of note, overexpressing Lamin A/C in atrium, which naturally lacks Lamin A/C expression leads to nuclear fragmentation. Together, these results indicate that the two chambers have distinct nuclear mechanics, possibly reflecting the underlying difference in the biomechanical environment. 3dpf Ventricle Atrium High Lamin A/C expression Low Lamin A/C expression Microtubules (MT) Cardiac forces Cardiac forces Ventricle Atrium Lamin A/C Lamin A/C MT stability MT stability 1. Nuclear morphology differs between ventricle and atrium a Ventricle Raw image Binary image Label map Nuclei segmentation Morphological filtering, CCL 3dpf myl7:H2B-mScarlet ventricle atrium Ventricle Heart rate + contractility myl7:mScarlet-LAP2b myl7:H2B-mNeongreen myl7:BFP-CAAX 3dpf Atrium Ventricle Atrium Ventricle Atrium Nif (10\u03bcM) DMSO IBMX (50\u03bcM) Manipulating microtubule stability alters cardiomyocyte nuclear morphology. myl7:EMTB-mNeongreen 3dpf myl7:H2B-mScarlet myl7:BFP-CAAX 3dpf Taxol DMSO Colchicine Ventricle Ventricle Ventricle Atrium Atrium Atrium Ventricle Ventricle Atrium myl7:mScarlet-LAP2b 5dpf Atrium Ventricle outer layer inner layer 4dpf Atrium Ventricle Ventricle 2. Cardiac force manipulation alters ventricle nuclear morphology vmhc amhc vmhc:laminA-mScarlet myl7:laminA-mScarlet myl7 * * * *enucleated cells amhc:laminA-mScarlet myl7:H2B-mNeongreen; myl7:BFP-CAAX 5dpf Overexpression of Lamin A/C is less tolerated in atrium. Microtubules are load-bearing cytoskeletal filaments that regulate mechanics6 and maintain nuclear architecture7. The Francis Crick Institute, 1 Midland Road, London NW1 1AT contact: laura.bader@crick.ac.uk 3. Lamin A/C is differentially expressed in ventricle and atrium The nuclear lamina is composed of lamins, intermediate filaments required to maintain the nuclear integrity1. Lamin A/C (lmna) is thought to regulate nuclear stiffness and mechanosensing2 and to mechanoprotect the genome3. Depletion of Lamin A/C softens nuclei and leads to increased number of mishappen nuclei2,4. In contrast, overexpression of Lamin A/C stiffens nuclei5. - How Lamin A/C regulates nuclear morphology \u2013 role of phosphorylation. - How microtubules regulate nuclear morphology \u2013 genetic tools. - Functional implications of differential nuclear morphology in ventricle vs. atrium. - Role of LINC (linker of the nucleoskeleton and cytoskeleton) complex. 4. Microtubule organisation regulates nuclear morhology 5. Further work We would like to express our gratidue to the Light Microscopy, Bioinformatics and Biostatistics STPs at the Crick, for their guidance and support at every stage of the project. Special thanks to the BRF for their assistance with fish husbandry. Without their knowledge, hardwork and expertise, this project would not have been possible. Lastly, we would like to thank the organisations who have provided financial support for this work, including The Francis Crick Institute and the British Heart Foundation. Acknowledgements [1] Gruenbaum, Y. and O. Medalia (2", "label": "poster"}
{"text": "Prescott College \u2014 For the Liberal Arts, the Environment & Social Justice Critical Review: Is Earth's Outer Core Liquid or a High Density Plasma? Daniel S. Helman Sustainability Education, Prescott College, 220 Grove Ave., Prescott, AZ 86301 danielhelmanteaching@yahoo.com Abstract This work explores composition and melting point data (or lack of data) related to Earth's outer core, and also the possibility of a high-density plasma composition, plus gives a background on Inge Lehmann's seismological observation demonstrating a solid inner core. Implications related to geomagnetic field dynamics are also presented, as are evidence in the rock record for changes to the geomagnetic field over time, including the intersection (if any) of such changes and the origin and development of life on the planet. Keywords geodynamo, plasma, metallic liquid, solid-density plasma, plasma channel, origin of life, geomagnetic field Inner and Outer: How Do We Know? Here are the words of Inge Lehmann, who made this discovery: Evidently, there was a reflection of the waves in the interior of the earth that caused them to emerge at a shorter epicentral distance. It was shown in a simple example how this could happen. I considered a globe in which a hard mantle surrounded a softer core, the radius of which I took to be five ninths of the surrounding sphere. The velocity of the longitudinal waves was 10 km/s in the mantle and 8 km/s in the core. It was then a simple matter to calculate the time curves arising from an earthquake that took place at the surface of the globe. The P curve that resulted from waves confined to the mantle ended at 112\u00b0 distance from the epicenter. P' consisted of two brances, as observed in the New Zealand earthquake. When the variation of the travel time was considered in relation to the angle of incidence, an estimate of the intensity could be obtained. In this way it was found that the intensity of the waves corresponding to the upper branch of the P' curve would be small. This was in accordance with the fact that it had been difficult to observe the upper branch. No rays emerged at epicentral distances between 112\u00b0 and 154\u00b0 (Figure 6). I then placed a smaller core inside the first core and let the velocity in it be larger so that a reflection would occur when the rays through the larger core met it. After a choice of velocities in the inner core was made, a time curve was obtained (Figure 7), part of which appeared in the interval where there had not been any rays before. The existence of a small solid core in the innermost part of the earth was seen to result in waves emerging at distances where it had not been possible to predict their presence. Gutenberg accepted the idea. He and Charles Richter (California Institute of Technology, Pasadena) placed a small core inside the earth and adjusted the radius of this small core until the calculated time curves agreed with the waves observed. Jeffreys was slower to accept the inner core. Jeffreys- Bullen time curves had been completed in 1935. In 1939, a new edition was published in which the inner core had been accepted. ... Inge Lehmann was born in 1888 and received her degree in mathematics in 1920. She later became chief of the Seismological Department of the Geodetic Institute of Denmark, which was established in 1928. As described in this article, she aided in setting up seismic stations in Greenland and Copenhagen. Her studies of the travel times of a special phase led to the discovery of the inner core of the earth in 1936. [1] Is the Outer Core a Liquid or a Plasma? Consider the following quote in light of how a plasma is defined: \u201cThe best hard sphere model for the core is a transition metal liquid whose valence electrons form an electron sea bathing and charge-compensating the spherical ionic cores.\u201d [2] The term metallic (or metal) liquid also appears in text related to the core of Jupoter: \u201cJupiter's magnetic field is caused by convective dynamo motion of electrica", "label": "poster"}
{"text": "INTRODUCTION On the frontlines of fighting the COVID-19 pandemic, chest imaging serves as an indispensable tool in the assessment of disease severity, monitoring the disease progression as well as for treatment planning. With only a handful of reports on radiographic patterns of COVID-19 infection across the literature, we aim to describe the radiographic characteristics of COVID-19 pneumonia in Malaysia. Chest radiographs (CXR) of laboratory confirmed COVID-19 patients in Hospital Tawau, Sabah were retrieved and retrospectively analyzed by two radiologists. The radiographic patterns, distribution among subgroups, and evolution of the disease over time were determined. Criteria Findings Frequency (%) Baseline Chest Radiographs Normal 45 (54.9) Abnormal 37 (45.1) Lung Changes Ground glass opacities 29 (35.4) Consolidation 7 (8.5) Interstitial opacities 4 (4.9) Nodular opacities 1 (1.2) Distribution Peripheral 29 (35.4) Central 2 (2.4) Diffuse 5 (6.1) Lung Involvement Right lung 6 (7.3) Left lung 16 (19.5) Bilateral lungs 15 (18.3) Zonal Predominance Upper zone 4 (4.9) Middle zone 3 (3.7) Lower zone 24 (29.3) No zonal predominance 6 (7.3) Focality Focal 17 (20.7) Multifocal 20 (24.4) Other features Pleural effusion 3 (3.7) Pneumothorax 1 (1.2) Pulmonary nodules 1 (1.2) Lymphadenopathy 0 (0) Follow up Radiographs (n=38) Normal baseline CXRs becoming abnormal 0 (0) Resolution 6 (15.8) Improvement 9 (23.7) Progression 3 (7.9) Computed Tomography (n=5) Typical COVID-19 features 3 (60.0) 82 patients included MATERIALS AND METHODS RESULTS 65 (79.3%) 17 (20.7%) Mean age of 37 \u00b1 15 years 25 8 18 16 1 5 9 24 40 9 16 33 6 2 4 45 M ale Female Symptomatic Asymptomatic Child ren Elde rly Comor bid No Comorb id DISTRIBUTION OF RADIOGRAPHS ACCORDING TO SUBGROUPS Normal CXR Abn ormal CXR with CO VID-1 9 pn eumon ia fe atu res CXR shows ground glass opacity at right lower zone. Coronal CT image shows ground glass opacity at right lower zone corresponds to the finding on radiograph. Asymptomatic COVID-19 patient with consolidation at the left upper zone (arrow) in the baseline radiograph with complete resolution of the opacities on day 5 of admission. REFERENCES C-07 NMRR NO:20-698-54570 CORONAVIRUS DISEASE -2019 (COVID-19): A RETROSPECTIVE REVIEW OF CHEST RADIOGRAPHS IN 82 PATIENTS. Mohana Letchumanan1, Adi Afiq Bin Md Anour1, Shubash Shander Ganapathy2, Syaman Harry1, Nik Shah Hizan Binti Nik Lah1, Norlimah Binti Arsad3, Nur Farhana Binti Ahmad Fisol4 1Department of Radiology, Tawau Hospital, 2Institute for Public Health, National Institutes of Health, 3Director of Tawau Hospital,4Clinical Research Center, Tawau Hospital 1. Choi H, Qi X, Yoon SH, Park SJ, Lee KH, Kim JY, et al. Extension of Coronavirus Disease 2019 (COVID-19) on Chest CT and Implications for Chest Radiograph Interpretation. Radiology: Cardiothoracic Imaging 2020; 2(2): e200107. 2. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395:497-506. 3. Lomoro P, Verde F, Zerboni F, Simonetti I, Borghi C, Fachinetti C, et al. COVID-19 pneumonia manifestations at the admission on chest ultrasound, radiographs, and CT: single-center study and comprehensive radiologic literature review. Eur J Radiol 2020; 7: 100231. CONCLUSION COVID-19 pneumonia presented with a specific radiographic pattern, comprising of ground glass opacities in peripheral and basilar distribution, affecting a single lung field. We observed these lung changes in both symptomatic and asymptomatic group of patients, and was more frequently manifested by patients with symptoms and comorbid, and those over 60 years of age. Chest radiograph is a useful adjunct screening tool, and in combination with clinical and epidemiological assessment may facilitate in early diagnosis of COVID-19 pneumonia. The authors would like to thank the Director General of Health, Malaysia, for the permission to present this poster", "label": "poster"}
{"text": "Workflow Tool for Archaeological Experiments and Analytics Workflow Tool for experiments We are developing an easy-to-use visual workflow tool that will allow researchers to record and illustrate meta- and paradata: experimental design, the protocol of sample preparation, procedure or analysis. The tool incorporates different types of experimental setup, ranging from high-tech controlled automated procedures in a lab to full-scale reconstructions in the field or well-documented re-enactment by a broader public (CC). Users will be able to customize the developed prototype, and increasing familiarity with their needs will be used to improve it. Experiments, reconstruction, replication and reproduction A lack of standards and tools for recording and reporting on archaeological experiments and analytics hinders comparison, scientific knowledge exchange and the evaluation of data quality. We are trying to fill this gap by developing a flexible, easy-to-use visual work-flow tool that will allow researchers to record meta- and paradata: experiment design plus protocols of sample preparation procedures and/or analysis. The need for such a tool has long been recognized, but resources have been lacking. The aim is to produce a prototype of a tool that can be continually improved in line with the needs of our community. About the Poster NFDI4Objects Community Meeting 2024, Mainz. Leibniz-Zentrum f\u00fcr Arch\u00e4ologie (LEIZA) Ivan Calandra, Geoff Carver, Jo\u00e3o Marreiros, Allard Mees, Guido Heinz, Florian Thiery Leibniz-Zentrum f\u00fcr Arch\u00e4ologie Citation Callandra, Carver, et al. (2024). Workflow Tool for Archaeological Experiments and Analytics. Zenodo. DOI: 10.5281/zenodo.13799052. 1) Monrepos 2) https://denkmalstiftung-baden-wuerttemberg.de/wp-content/uploads/2022/10/Denkmalstiftung-Baukunst_Pfahlbau.jpg 3) https://i.pinimg.com/736x/0c/a0/87/0ca087ca4ce96a5038eaf4608a7f4f2e.jpg 4) https://www.crystalking.com/hubfs/ancientrome.jpg 5) TraCEr List and reorder tasks Start menu Generate task flowchart Populate inventory Plan an experiment 1 2 3 4 5 https://tools.leiza.de/workflowtool/", "label": "poster"}
{"text": "z The Impact of Digital Behavior on Poly-substance Use Among American High School Students: An Analysis using YRBS 2017 to 2021 Laggy George MPH Brooks College of Health INTRODUCTION \u00a7 Poly-Substance Use (PSU): Significant public health concern especially among adolescents. \u2022 Age of Onset: 15-19 years critical for substance use initiation (Blanco et al.,2018). \u2022 Poly substance use is more prevalent than single substance use (CDC,2023). \u2022 Screen Time (ST): Associated with physical, social, and psychosocial health impacts (Connolly et al., 2024 ) \u2022 Explore the association between screen time and PSU in American High School students, using a cross-sectional analysis with YRBS 2021 data. \u2022 PSU includes concurrent use of 2 or more drugs intentionally or unintentionally (CDC,2023). \u2022 Excess screen time defined as more than 2h/day apart from course work ((AACAP, 2024) OBJECTIVE \u2022 Data Source: YRBS 2017-2021, (N=45,132). \u2022 Dependent: PSU (concurrent use of substances). \u2022 Independent: Screen time, Socio-demographic (gender, age, race/ethnicity, grade), Lifestyle factors (mental health, physical activity, sleep, smoking, alcohol use, opioid misuse). \u2022 Statistical Analysis: Chi-square and Multiple logistic regression Using SAS 9.4 English. RESULTS \u2022 Baseline characteristics: \u2022 Final sample size n=7,251 \u2022 48% females, 52% males. \u2022 Majority aged 16-17 years (24%). \u2022 Non-Hispanic Whites 53%, Hispanics 25%. \u2022 PSU: 21%, and Screen Time >2 h: 91% \u2022 ST and PSU Association: \u2022 Higher odds of PSU with >2 h per day of ST (AOR = 1.6, 95% CI = 1.03-2.54) Increased odds of PSU also with: \u2022 Dose response with age, >18yrs, (AOR = 27.7, 95% CI = 5.84-131.9) \u2022 Opioid misuse and Alcohol 3 times higher odds, while smoking 10 times higher odds. \u2022 Gender and Race differences: Males, non- Hispanic Blacks had higher odds (Table 1) \u2022 Physical activity 5 days a week for 60 mins/day (AOR = 0.8, 95% CI = 0.68-0.99) \u2022 Trends (2017, 2019, 2021): \u2022 PSU higher odds 2019 (AOR = 1.3, 95% CI 1.05-1.56, p=0.015) \u2022 Excess Screen Time: Significant predictor of PSU; higher likelihood of PSU. \u2022 Mental Health: Poor mental health linked to higher likelihood of PSU. \u2022 Smoking, alcohol, opioid misuse increased the likelihood of PSU. \u2022 Physical Activity: Protective effect against PSU. \u2022 Prevention Strategies: Focus on reducing screen time, promoting physical activity, and integrating mental health services. METHOD Table 1 Multiple Logistic Regression Analysis Note: n = unweighted sample size. % = weighted percentage. Significant at p<0.05 \u2022 Target lifestyle modifications, including physical activity in highschoolers to reduce screen time. \u2022 Health education for parents and adolescents regarding prescription misuse, and substance misuse. \u2022 Emphasis on High-risk subgroups. 10% 68% 11% 55% 17% 51% 15% 21% 90% 32% 89% 45% 83% 94% 85% 79% NONE CURRENT ALCOHOL NONE CURRENT OPIOID MISUSE NONE PRESENT SCREEN TIME <=2 H/D >2H Prevalence of Polysubstance Use among High School Students in the United States from 2017-2021 Poly Substance Use (No) Poly Substance Use (Yes) \u2022 Chi-square analysis \u2022 All values significant at p <0.05 Smoking Variable Odds ratio 95% CI Gender Female reference Male 1.3 1.04-1.63 Age (years) >12-13 reference 14-15 21.7 4.92-95.76 16-17 24.5 5.40-111.24 >18 27.7 5.84- 131.91 Race NH White reference NH Black 1.8 1.24- 2.47 Physical Activity >= 1h/day <5 days a week reference >=5days 0.8 0.68-0.99 Mental Health Good reference Not good 1.9 1.47-2.37 Current Smoking <=30 days None reference Current 9.7 7.78- 12.09 Current Alcoholism <=30 days None reference Current 3.4 2.58-4.54 Prescription Opioid Misuse No reference Yes 3.1 2.50-3.72 Screen time <2h per day reference >2h per day 1.6 1.03-2.54 REFERENCES ACKNOWLEDGEMENTS \u2022 Aacap. (n.d.). Screen Time and Children. \u2022 Blanco, C., Fl\u00f3rez-Salamanca, L., Secades-Villa, R., Wang, S., & Hasin, D. S. (2018). \u2022 Centers For Disease Control and Prevention. (2023). \u2022 Connolly, S., Govoni, T. D., Jiang, X., Terranella, A., Guy, G. P., Gr", "label": "poster"}
{"text": "UNAVCO VIVO ingest (python scripts) Curated author disambiguation Disambiguation Match List VIVO Triple Store Check for existing objects in VIVO using VIVO Query API Get metadata from CrossRef using CrossRef API Employees MS Dynamics Membership xml ORCID Datasets UNAVCO API (in development) Abstracts web scraping > json RDF Publications Web of Science Google Scholar 0% 25% 50% 75% 100% Connect with social media databases that contain information about the researcher (e.g. Research Gate, LinkedIn, Twitter, Facebook) Generate biographies, CVs, resumes or other information Connect to institutional web page Be discoverable (ef\ufb01ciently and accurately) in Google or other search engines Which other features would you like an information platform that displays/describes your work to have? Not essential, should not be added Not essential, but could be added Important Very Important 0% 25% 50% 75% 100% Podcasts produced Meetings attended Past professional volunteer services/leadership positions Teaching tools produced Videos produced Webinars/workshops taught Presentations given Past grant awards Courses taught Students advised Software tools produced Algorithms/models developed Images/graphics created Professional awards received Instruments/tools developed Datasets produced Which of the following \u201cproducts\u201d are most important to include in an information platform that displays/describes your work (e.g. on a faculty webpage or in a researcher pro\ufb01le)? Ask a colleague Web sites of individual researchers Institutional library catalog Literature indexes, e.g. Web of Science Google or another search engine How do you search for publications? Never Sometimes Often Always Social/researcher networking services (e.g. Research Gate, LinkedIn, Facebook) Ask a colleague Published literature, e.g. journal articles University web sites Google or another search engine How do you search for people (e.g. a colleague who may have moved from one university to another)? 0% 25% 50% 75% 100% Institutional library catalog Ask a colleague Google or another search engine Published literature, e.g. journal articles Data center web sites How do you search for data (e.g. All time series from GPS stations in southern California)? Company or tool- producer web sites Institutional library catalog Ask a colleague Published literature, e.g. journal articles Google or another search engine How do you search for tools (e.g. all geodetic and seismic instruments in or around the Marmara Sea)? Figure 2 (above): The VIVO application comes pre-packaged with an ontology (semantic vocabulary) that doesn\u2019t cover many geodetic concepts. Figure 2 illustrates a relationship not fully supported in the VIVO-ISF ontology. A project will have many stations which may host multiple instruments (e.g. GPS and meteorological equipment), which are attached to one or more platforms (see Figure 3 for an example). Figure 4 (above): Datasets can be linked to a major geophysical event, such as an earthquake. The products shown, and others such as software and models, are tied to skos:Concepts, which are pulled from controlled vocabularies whenever possible. Geodesy-specific concepts were added to the application to capture research areas and expertise. The VIVO application was customized to better capture the needs of the geodesy community. The customizations implemented so far include ontology extensions and mapping capabilities. For the initial rollout, the database was populated from a diverse array of sources, summarized below (Figure 5). As the application matures, relevant data will be added automatically using APIs from the NSF, ORCID, and CrossRef. Guiding development of a semantic web app: End-user engagement in the EarthCollab project Gross, M. Benjamin1, Johns, Erica M.2, Rowan, Linda R.1, Mayernik, Matthew3, Khan, Huda2, Daniels, Michael D.3, Krafft, Dean B.2 1) UNAVCO, Boulder, CO 2) Cornell University, Ithaca, NY 3) National Center for Atmospheric Research, Boulder, CO This materi", "label": "poster"}
{"text": "Lost in scienti\ufb01c literature? Too busy to stay on top of your \ufb01eld? Find in\ufb02uential research with a click of a button. Get to highly cited articles, follow updates on new publications, browse grant database to see what is funded in your \ufb01eld. Too few or too many results, having to search in numerous places - literature research can be time-consuming. Europe PMC provides free access to biomedical peer-reviewed publications and o\ufb00ers advanced search tools to help you navigate the world of scienti\ufb01c knowledge. Try Europe PMC for A-Z of life sciences literature: publications, patents, theses, and more. It combines the power of PubMed and PMC with a single search for both abstracts and full text. Even most speci\ufb01c requirements can be addressed with Europe PMC advanced search. Find clinical reviews, or search speci\ufb01cally for articles that mention CRISPR in the methods section. Hard to locate primary data and \ufb01nd evidence? Want to re-use a dataset from a study? Discover links to data records directly from the full text. Europe PMC links to PDBe, UniProt, ChEMBL, and many more public molecular resources. Looking for evidence to support your hypothesis? Scan articles for concepts like chemicals or organisms, and spot protein interactions or gene-disease relations with an annotation tool. No time to gather the evidence of your impact? Claim your works to your unique ORCID identi\ufb01er with a simple tool from Europe PMC and enjoy immediate bene\ufb01ts - an Author Pro\ufb01le showcasing your publication list and citation rate. Find your way with Europe PMC! www.europepmc.org", "label": "poster"}
{"text": "Experiment 1: 4 Amaranthaceae species & Glycine max \u2022 The study was conducted at the following field sites in southern Illinois: Cypress Creek National Wildlife Refuge (A. japonica), Chestnut Hills Nature Preserve (A. japonica), Belleville Research Center (A. palmeri, A. tuberculatus, G. max), and Beall Woods State Park (I. rhizomatosa). \u2022 Ten individual plants of each species at each site were randomly selected for measurements (see Sampling Method above). \u2022 Differences among wavelengths in % reduction taking into account plant height as a covariate were tested using an ANCOVA in SAS. Experiment 2: Achyranthes japonica in competition with Microstegium vimineum \u2022 The field site was located at Chestnut Hills Nature Preserve in Pulaski County, Olmsted, Illinois. \u2022 Twenty 1m2 quadrats containing mixed communities of A. japonica and M. vimineum with different proportions of A. japonica were sampled three times (T1, T2, T3) during July. \u2022 Vegetation was sampled by visually estimating plant cover in each 1m2 quadrat based upon the modified Daubenmire method for cover estimation. \u2022 Four individual plants within each plot were randomly selected for measurements (see Sampling Method above). \u2022 The relationship between the proportion of A. japonica and height to the mean % reduction of each light wavelength was examined using a stepwise regression in SAS. Introduction Materials and Methods Experiment 1 \u2022 All five species had significant differences between light wavelengths (Fig. 1). \u2022 The mean % reduction of the blue wavelength was consistently the highest among the four wavelengths, nearing 100%, followed by the red and far-red wavelengths, respectively (Fig. 1). \u2022 The far-red and white wavelengths had similar levels of reduction at approximately 44% in A. japonica at Cypress Creek and 59% in I. rhizomatosa, (Fig. 1a, e), while A. japonica at Chestnut Hills had a greater reduction in the white than far-red wavelength (Fig. 1b). Experiment 2 \u2022 There was a positive relationship between the mean % reduction in both the blue and red wavelengths and height for T1 and T3 (Fig. 2a, c). \u2022 There was a negative relationship between the mean % reduction in the far-red wavelength and the proportion of A. japonica for T1 (Fig. 2b). \u2022 There was a positive relationship between the red:far-red ratio and height for T1 and T2 (Fig. 2d). \u2022 There was a negative relationship between the mean % reduction of red wavelength and the proportion of A. japonica and a positive relationship with height for T2(Fig. 2e). \u2022 There were no significant relationships detected for the white wavelength. a) Blue Wavelength (Height) Height (cm) 20 30 40 50 60 70 80 90 100 Mean % Reduction 96.0 96.5 97.0 97.5 98.0 98.5 99.0 99.5 100.0 Time 1: blue = 97.666 + 0.01798 (height) F1,18 = 8.44, p = 0.0094, R2 = 0.3192 Time 3: blue = 97.744 + 0.01443 (height) F1,18 = 5.16, p = 0.0356, R2 = 0.2229 40 50 60 70 80 90 100 40 50 60 70 80 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 Mean % Reduction Height (%) Proportion of Achyranthes japonica e) Red Wavelength (Height & Proportion of Achyranthes japonica) 40% 50% 60% 70% 80% 90% 100% Time 1 Time 1 Regression Time 2 Time 2 Regression Time 3 Time 3 Regression c) Red Wavelength (Height) Height (cm) 20 30 40 50 60 70 80 90 100 Mean % Reduction 40 50 60 70 80 90 Time 1: red = 44.248 + 0.44211 (height) F1,18 = 11.35, p = 0.0034, R2 = 0.3868 Time 2: red = 60.15926 - 9.66842 (propachj) + 0.34795 (height) F2,17 = 9.8; p = 0.0015; R2 = 0.5354 Time 3: red = 56.29869 + 0.25306 (height) F1,18= 11.79, p = 0.0030, R2 = 0.3958 b) Far-Red Wavelength (Proportion of Achyranthes japonica) Proportion of Achyranthes japonica 0.2 0.4 0.6 0.8 1.0 Mean % Reduction 35 40 45 50 55 60 65 70 Time 1: far-red = 53.72696 - 9.15980 (propachj) F1,18 = 6.00, p = 0.0248, R2 = 0.2501 d) Red:Far-Red Ratio (Height) Height (cm) 20 30 40 50 60 70 80 90 100 Red:Far-Red Ratio 0.6 0.8 1.0 1.2 1.4 1.6 1.8 2.0 2.2 2.4 2.6 Time 1: ratio = 0.85063 + 0.01217 (height) F1,18 = 7.63, p = 0.0128, R2 = ", "label": "poster"}
{"text": "NHS East Genomics has 4 main partner NHS Trusts: Cambridge University Hospitals | Norfolk and Norwich University Hospitals Nottingham University Hospitals | University Hospitals of Leicester www.eastgenomics.nhs.uk Learning from the implementation of DPYD pharmacogenetic testing across 18 acute NHS Trusts Authors: Aris Saoulidis1, Paul Selby1, James Drummond1, Sarah Hunter1, Colin Spencer1, Sarah Pacey1, Richard Sandford1 1NHS East Genomic Medicine Service Alliance & Genomic Laboratory Hub (East Genomics). Correspondence: Aris.Saoulidis@nhs.net Informatics interoperability between genetic labs and prescribing software is key Clinical teams have no or limited functionality to seamlessly track the test progress, and test results are primarily transferred as PDF reports. Current manual methods of tracking and reporting test results to clinicians contribute to perceived longer test turnaround times by clinicians, despite timely lab reporting. Thus, automated reporting between NHS systems is needed. The current healthcare informatics exchange standards and channels (HL7 and FHIR) offer opportunities to support PGx interoperability.4 However, the community requires consensus on standardising the nomenclature of PGx reporting to clinicians agnostic to prescribing systems. Currently, Ontology and Medical terms (SNOMED CT) are not aligned with clinical PGx guidelines, introducing challenges of clinical PGx reporting, as for example, the UK Chemo Board guidance have six levels of DPD classification as opposed to three SNOMED CT codes. Figure 1: Number of medicines with pharmacogenomic potential prescribed by pharmaceutical class Patient outcomes and data collection Interoperability will support systematic data collection needed on treatment efficacy and toxicity for large scale adoption of PGx. Finally, we welcome the community\u2019s approach to further identify how to increase and review systematic toxicity reporting, alongside re-assessment of expanded testing for other DPYD variants across different ethnicities. Background Fluoropyrimidines (capecitabine, 5-fluorouracil/5FU) are systemic anti-cancer therapy (SACT) in solid cancer. Fluoropyrimidines are metabolised by the enzyme dihydropyrimidine dehydrogenase, encoded by the DPYD gene. Pre-treatment genetic screening for DPYD pharmacogenetic (PGx) variants can predict and prevent fluoropyrimidine toxicity and was mandated prior to 5FU/capecitabine treatment by the MHRA in October 20201; a Clinical Commissioning Urgent Policy Statement was published by NHS England in November 20202. DPYD testing already takes place across 18 East of England and East Midlands NHS Trusts offering fluoropyrimidine systemic anti-cancer treatment, albeit with significant variation. Most Trusts are currently following the UK Chemotherapy Board\u2019s 2020 Personalised Medicine Approach for fluoropyrimidine-based therapies3. Overall, DPYD testing is now established in the NHS, preventing toxicity and improving treatment for patients with clinically-significant DPYD variants. We share our key learnings from the East Genomics DPYD transformation project. 1. 5-fluorouracil (intravenous), capecitabine, tegafur: DPD testing recommended before initiation to identify patients at increased risk of severe and fatal toxicity. Medicines and Healthcare products Regulatory Agency. October 2020 accessible from https://www.gov.uk/drug-safety-update/5-fluorouracil-intravenous-capecitabine-tegafur-dpd-testing-recommended-before-initiation-to-identify- patients-at-increased-risk-of-severe-and-fatal-toxicity 2. Clinical Commissioning Urgent Policy Statement Pharmacogenomic testing for DPYD polymorphisms with fluoropyrimidine therapies\u2013 NHS England, November 2020 (URN 1869) accessible from: https://www.england.nhs.uk/publication/clinical-commissioning-urgent-policy-statement-pharmacogenomic-testing-for-dpyd-polymorphisms-with-fluoropyrimidine-therapies/ 3. Personalised Medicine Approach For Fluoropyrimidine-based Therapies. UK Chemother", "label": "poster"}
{"text": "Research Libraries have a long history of studying the users of their collections, but these theories and methods have not translated easily into stud- ies of digital services, much less of digital data services. By combining information from DANS transaction logs with a user database we gain insights into who uses the archive and how. Curation Images form the largest part of the archived \ufb01les. Most of them stem from archeological data- sets. One of the biggest challenges in long-term preserva- tion is to still be able to read/display digital content - \ufb01le type recognition is a prerequisite. Monitoring of the amount of datasets, their composition in terms of \ufb01les, \ufb01le size, and \ufb01le type is needed to design strategies for storage and access. Here we show a polar bar chart of mime type frequencies (above) and the growth of the archive (below). Datasets with a later creation date have more \ufb01les, and there are more datasets each year. Before 2000 the archive grew yearly by less than 2 GB. After 2000 we observe a dramatic change in the growth regime, adding between 100 and 500 GB each year. Navigation From the transactions logs, we extracted the 70 most frequently used search terms across all sessions. Clustering strings reveals groups of topics: archeological sources (see cluster 1-4), elections (*kiezer*), mobility (*mobiliteit*), or living conditions (*woon*). OPACs (Online Public Access Catalogue) determine how the user sees the collections of a digital library or archive. Visualizations of a collection can bridge the gap between the old physical and the new digital. But what to visualise? Geographic regions and periods in time? The interconnectedness of search terms and their possible targets or the composition of the collection in terms of targeted audiences? As of May 2015, EASY contains 29,743 published datasets (the equivalent of a \u201ccollection\u201d in Dublin Core ). The majority of submitted datasets originate in archaeology, for which EASY is a legal deposit archive. The majority of downloaded datasets are from the social sciences. See a showcase of a visual exploration of EASY at: http://www.drasticdata.nl/projects.htm#DansEasy Christine Borgman, Andrea Scharnhorst, Henk van den Berg, Herbert Van de Sompel, Andrew Treloar christine.borgman@ucla.edu, andrea.scharnhorst@dans.knaw.nl, henk.van.den.berg@dans.knaw.nl, herbertv@lanl.gov, andrew.treloar@ands.org.au Surprisingly little is known about the uses and users of digital data archives, about relationships between users and the sta\ufb00 of data archives, or how these behaviors vary by discipline, geographic region, policy, and other factors. Digital data archives are not a single type of institution - they vary widely in organizational structure, mission, collection, funding, and relationships to their users and other stakeholders. We present an exploratory study of EASY, the Electronic Self-Archiving SYstem, a digital archive hosted at DANS. DANS was founded in 2005 as an institute of the Royal Netherlands Academy of Arts and Scienc- es (KNAW) and of the Netherlands Organisation for Scienti\ufb01c Research (NWO). DANS is responsible for archiving 50 years of digital research data in the social sciences and humanities. We present a number of visual explorations with the goal of identifying methods for studying the contributors, consumers, and role of archivists in digital data archives. In particular we address RESEARCH about users; CURATION of digital content, and interfaces for NAVIGATION. [1] Christine L. Borgman, Andrea Scharnhorst, Henk van den Berg, Herbert Van de Sompel, and Andrew Treloar. \"Who Uses the Digital Data Archive? An Exploratory Study of DANS\" Information Today (2015). ! magnitude: 1000, 100, 10, 1 users sessions Number of logged in users and sessions, world!wide, 2011 ! 2014 ! magnitude: 1000, 100, 10, 1 users sessions Number of logged in users and sessions, 2011 ! 2014 !\"##$\"%&' (#$)* *+,-.(%$, -..+-.++*-\" /-#'. .$.)#0\".+-.#1%!\"*-%0.)#%'#$!%. .-01#*)*,%# .-01.#*)", "label": "poster"}
{"text": "Biological processes underpinning soil ecosystem services Methods Preliminary assessment A summary report, Soil Ecosystem Services: the current status and research priorities (Paterson, Glies, Yeluripati & Neilson, 2022) was completed, identifying knowledge-gaps with respect to biologically mediated processes underpinning soil ecosystem services. This report also identified research within the current RESAS Strategic Research Programme contributing to understanding of soil ecosystem services, and how this research links to current policy for soil governance in Scotland. Experimental approach Soils representing a diversity of classifications across cultivated land in Scotland were identified, including long-term experimental sites, where land use and management are known and supported by existing monitoring data. A set of approaches to quantify soil biological functions were applied, focusing on processes underpinning greenhouse gas fluxes, nutrient cycling, crop productivity and nitrogen leaching. The biological functions were selected, both for their direct relevance to soil ecosystem services, and as functions that are represented in biogeochemical models (i.e., the data will support refinement of these models). Results Example of soil functional analysis: Balruddery Centre for Sustainable Cropping Sustainable management, reduced tillage and application of organic amendments to substitute for mineral fertilisers, significantly affected microbial community abundance and composition, strongly impacting the physiological capacity of the soil microbiome to utilize a diversity of organic compounds (Fig. 1). Eric Paterson and Clare Cameron The James Hutton Institute, Craigiebuckler, Aberdeen Email: eric.paterson@hutton.ac.uk Introduction \u2022 Soil is a fundamental resource supporting delivery of ecosystem services underpinning societal, environmental and economic benefits. \u2022 Historically, these benefits have been linked closely to soils\u2019 capacity to sustainably support plant primary production for food, fibre, and fuel, thereby supporting human life and activities. \u2022 These provisioning services remain vital, particularly in the context of increasing global populations, a changing climate and competing pressures on land use. However, a host of other services that soils provide are now recognised to underpin environmental and cultural services that need to be considered in management and policy decisions relating to soils and land use. \u2022 The soils of Scotland are highly diverse, shaped by climate and their underlying geology, meaning that the ecosystem services that they can potentially support is variable. \u2022 Management of soils for single ecosystem services (e.g., greenhouse gas mitigation) has consequences for others (e.g., food production), and understanding these potential trade-offs, across diverse soils, is a focus of this research. Conclusions \uf0a7 The desk review of existing knowledge on soil ecosystem services identified successful use of soil properties to predict services that are primarily controlled by physico-chemical processes (e.g., resistance to erosion, water infiltration), but that prediction of biologically-driven functions (e.g., greenhouse gas fluxes, nutrient cycling), is more difficult, particularly in the context of dynamic changes associated with management practices. \uf0a7 The soil functional analyses identified strong soil-type effects on biological processes, and that for a single soil, management has a significant impact on the capacity of that soil to mediate processes underpinning greenhouse gas fluxes, element cycling, plant productivity and nutrient retention. Figure 1: Canonical Analysis of Principal Coordinates (CAP) of soil microbial community physiological diversity (MicroRespTM) for conventional (CON) and sustainable (SUS) management practices. These impacts of sustainable management practices on microbial communities were associated with significant effects on soil functions affecting nitrogen availabil", "label": "poster"}
{"text": "H63D Research Consortium Konferenzposter www.H63D.org Nur f\u00fcr akademische Zwecke! Typ 1, 2 & Oshtoran H63D-Syndrom Typ-1 H63D Syndrom Typ-1 f\u00fchrt zu einer spezifischen Konstellation: niedriges Ferritin und hohe Transferrins\u00e4ttigung, was zu einer Speicherung von nicht entfernbarem NTBI (nicht an Transferrin gebundenem Eisen) f\u00fchrt. Diese intrazellul\u00e4re NTBI- Akkumulation verursacht zun\u00e4chts unbemerkt subklinische Entz\u00fcndungen, die wiederum zu ersten Funktionsst\u00f6rungen, aber auch bereits zu meist erheblichen Organsch\u00e4den f\u00fchren k\u00f6nnen, insbesondere an Leber, Herz, Endokrinium und Gehirn. Typische Symptome basieren somit auf nur mit sehr speziellen Tests fassbaren subklinischen Entz\u00fcndungen, ungleich verteilt im Parenchym, oft bereits fr\u00fch begleitet von einer schleichenden Degeneration der Hoden, was zu Verkalkungen f\u00fchren kann. Zudem treten Narkolepsie mit Kataplexie und nahezu die gesamte Palette der so genannten non-motor Parkinson Symptome auf (wenig \u00fcberraschend beim Vorliegen einer Degeneration der Substantia nigra mit Bezug zu den Basalganglien). Vor Chelattherapien aller Art und Aderl\u00e4ssen muss gewarnt werden, da sie das Ferritin weiter reduzieren, w\u00e4hrend das toxische NTBI-Eisen im K\u00f6rper verbleibt. H63D-Syndrom Typ-2 Typ-2 zeigt einen unspezifischeren Ph\u00e4notyp mit einem bunten Strau\u00df an Symptomen und erfordert eine ausgesprochen umfassende Diagnostik durch Endokrinologen. Die Eisenregulation und dessen Auswirkungen auf den K\u00f6rper sind jedoch auch hier der Kern des Problems. Die Anwendung von Aderl\u00e4ssen h\u00e4ngt vom Ferritinwert ab und muss sorgf\u00e4ltig \u00fcberwacht werden. H63D-Syndrom Typ-3 Oshtoran-Syndrom Das Oshtoran-Syndrom (H63D Typ-3) beginnt mit einer immunologischen Sch\u00e4digung (progressiv, persistierend) nach einer Infektion, insbesondere nach dem PANS/PANDAS Syndrom. Die in der Folge klinisch aktivierte homozygote HFE H63D Mutation f\u00fchrt langsam aber sicher zu Symptomen, die jenen von Typ-1 \u00e4hnlich sind, doch erheblich radikaler und persistierender. Typisch f\u00fcr Typ-3 (Oshtoran) ist eine wellenrtige Progredienz mit teils vital gef\u00e4hrlichen Symptomen. Wie auch bei dem o.g. Typ-1 kommt es wellenartig zunehmend zu ernsten Organsch\u00e4den (strukturell und funktionell). Merw\u00fcrdig oft findet man in der Leber eine FNH. In den fortgeschrittenen Stadien tritt oft eine PDH- Zytopathie (eine Mitochondriopathie) auf. Die durch ANS/ZNS, Pathways, Botenstoffe und zusammen \u00fcber die Innervation ausl\u00f6sbaren Fehlsteuerungen von Organen, Endokrinium und Immunsystem macht das Oshtoran Syndrom zu einem potentiell letal endenden, \u00e4u\u00dferst schwer diagnostizierbaren und nicht kausal behandelbaren Ph\u00e4notyp. Daher ist die Behandlung fast immer nur supportiv und nicht kurativ, mit au\u00dferordentlich starker Medikation. H63D-SYNDROM Eine der riskantesten Orphan Diseases kondensiert f\u00fcr Laien und Eilige erkl\u00e4rt. Das H63D-Syndrom Das H63D-Syndrom ist eine genetische Erkrankung, die durch eine homozygote Mutation im HFE-Gen H63D verursacht wird. Diese Mutation kann in seltenen F\u00e4llen zu einer Vergiftung durch NTBI-Eisen f\u00fchren, wie dies in sehr \u00e4hnlicher Weise beim Morbus Wilson mit Kupfer geschieht. Eine Vielzahl von immer schlimmer werdenden Funktions- und Organsch\u00e4den ist die Konsequenz. Auch hier die Parallele zum Morbus Wilson. Im Gegensatz zu herk\u00f6mmlichen Formen der Eisen\u00fcberladung (das H63D- Syndrom ist keine H\u00e4mochromatose) die durch hohe Ferritinwerte gekennzeichnet sind, zeichnet sich das H63D-Syndrom durch niedriges Ferritin und eine erh\u00f6hte (>50%, meist >60%) Transferrins\u00e4ttigung aus. Dies f\u00fchrt bei jedem Menschen zur Bildung von toxischem NTBI-Eisen und folglich zu einer Ablagerung von NTBI-Eisen in kritischen Organen wie z.B. Leber, Herz und Gehirn. In kleinen Mengen ist dies normal, kann aber erhebliche Folgen haben, wenn man zu lange (meist Jahre) zu viel NTBI in seinen Parenchymzellen und Gehirn speichert, wie dies am H63D-Syndrom Erkrankte erleben. Meist leiden die Patienten daher \u00fcber Jahre hinweg an immer mehr Symptomen: 50 bis 90 sind", "label": "poster"}
{"text": "Combined effects of alternative casing materials and biostimulants on Agaricus bisporus yield and disease incidence Florien A. Gorter1, Marc Hendriks1, Odette Mendes1, Carin Lombaers1, Marjon Krijger1, Ed Hendrix1, William Kay2, Gail Preston2, Jaime Carrasco2,3, Pablo Martinez3, and Jean M. van der Wolf1 1 Wageningen University and Research, Biointeractions and Plant Health, Wageningen, NL, 2 University of Oxford, Department of Plant Sciences, Oxford, UK, 3 Mushroom Technological Research Center of La Rioja (CTICH), La Rioja, Spain Background Casing soil is a complex substrate that is essential for the fructification of Agaricus bisporus mushrooms. Currently, casing soil mainly consists of peat, which is used because of its excellent physical, chemical and biological properties. However, peat excavation is associated with CO2- emissions and biodiversity loss. As such, the mushroom industry is looking for alternative casing materials that can be used to\u2014partially or wholly\u2014replace peat. We identified materials that can be used to partially replace peat without major negative effects on mushroom yield or disease incidence. Performance of alternative casing materials might be improved by the addition of beneficial microbes. Bacterial strains from peat have been isolated that potentially enhance fructification of the mushroom crop. Strains have also been identified that selectively inhibit fungal pathogens such as Lecanicillium fungicola (dry bubble disease) in vitro. Addition of selected biostimulant strains might thus help to overcome the drawbacks associated with the use of alternative casing materials and reduce the use of pesticides. Results Objective Experimental set-up Conclusions \u2022 Biostimulants had no effect on yield or dry bubble disease incidence. \u2022 Biostimulant A was able to persist in casing soil during two flushes. \u2022 Biostimulant B populations decreased rapidly in casing soil. Button mushrooms were grown on three different casing soils (peat, alternative I and alternative II) under standard conditions in an experimental mushroom facility for two consecutive flushes. Mushroom yield was determined in the absence vs. presence of biostimulants A, B or a mix of A, B, and C. Disease incidence following inoculation with Lecanicillium fungicola was determined in the absence vs. presence of biostimulants A, B or a mix of A, B, and C. Population dynamics of biostimulants A and B in the absence of Lecanicillium was determined using targeted TaqMan qPCR assays. Acknowledgements The work presented here was performed as part of the H2020 BIOSCHAMP project (Grant Agreement 101000651), which aims to take an integrated approach to tackle mushroom cultivation challenges. BIOSCHAMP partners are: the Spanish Associations of Mushroom Growers (ASOCHAMP), Research Center of Mushrooms (CTICH), Inagro vzw, Wageningen Research, IRNASA-CSIC, University of Oxford, Kekkil\u00e4- BVB, NEWFOSS, FERTINAGRO, EUROCHAMP, UGLK, EKOFUNGI and Innovarum. Wageningen University & Research P.O. Box 123, 6700 AB Wageningen Contact: florien.gorter@wur.nl T + 31 (0)317 48 44 45 Figure 4. Population dynamics of biostimulants in the absence of Lecanicillium fungicola. Absolute abundance determined using TaqMan assays. Ct = cycle threshold, i.e. number of PCR cycles required for the fluorescent signal to cross the threshold. Detection threshold: 35. Biostimulants were added at the beginning of the 1st and 2nd flush (orange arrows) and sampling was performed at multiple time points during the flushes. A) Biostimulant A. B) Biostimulant B. 0 5 10 15 20 25 30 35 40 45 T0 T1 T2 T3 T4 T5 T6 T7 Ct Sampling timepoints A 0 5 10 15 20 25 30 35 40 45 T0 T1 T2 T3 T4 T5 T6 T7 Ct Sampling timepoints B Figure 1. A) Agaricus bisporus growing in the experimental mushroom facility. B) Lecanicillium fungicola (dry bubble disease) causes deformations and brown spots on the mushroom (pictures from Berendsen et al., 2010, A = healthy, B-D = diseased). A B Figure 2. Effect of biostimulants ", "label": "poster"}
{"text": "How does this discipline interpret the question? What methods would this discipline use to investigate the question? How would (someone in) this discipline know they had a good answer? Helping Hands\u2026 What expertise/ methods/norms of thought can you draw on from other disciplines to support or contrast? Additional notes. 3 Building Permeable Classroom Walls: Forming links across the curriculum What is the misperception/ boundary/ epistemology you are trying to address? Can this be checked in another classroom? Will the session(s) be co-taught? Taught separately across subjects? Draw on knowledge from other subjects Building on Current Practice 5-minute lesson plan \u2013 bridging subject boundaries Developing Epistemic Insight: How can the students be supported to answer these three questions? What is the Big or Bridging Question? Learning Objectives: Before they investigate, what Do they already need to know? How does this map on to other areas of the school curriculum? Is this building on existing knowledge? Challenging misperceptions? Acting as extension? 1 2 How \u2018Green\u2019 are electric cars? Science: Identify how fuel production is sourced RE/Stewardship: Discuss who holds responsibility and who we are responsible to and why when mining resources and taking care of the environment. Geography: Investigate the location of where fuel resources are mined Identify previous learning/gaps in learning. Science: batteries, electrolysis, disposal, rare resources/recycling RE/Stewardship: The ethics of enforcing electric cars Geography: Location of resources Economics: Affordability, Accessibility (Market forces) Science: Establishing sources for electricity (fossil fuels/renewables) and how they are mined, pollution RE/Stewardship: Consider who benefits and who is disadvantaged from electric car production (inc sourcing materials). Awareness of demand on resources, production processes, politics, monopolise materials. Science: Undertake reliable tests, and reproducible experiments. Field studies. RE/Stewardship: Investigate the impact on quality of life (i.e. emissions, noise, global versus local perspective, impact on wildlife, rights of individuals, changes to/effects on societal behaviour Science: Reliable data checked against wider sources (misperceptions by car co\u2019s). Replicable and tested by multiple sources. RE/Stewardship: Focus on judgements, beliefs and values in religious texts, ethical principles. Justifying actions from religious texts or worldviews. Geography \u2013 location of resources, damage to the environment, impact on local population. Geography \u2013 fieldwork, data analysis focused on people, places and spaces. Geography (physical and human) - data collection is both quantitative (mapping, surveys) and qualitative (interviews). Is this purely a science question? Are the environmental benefits of electric cars overstated? Collaborate with teachers of other disciplines. Learn from colleagues by talking about the same topic/big question and share their expertise and space to break down classroom boundaries. Co-planning/co-teaching with other subject specialist to work on the same topic/question from various disciplinary perspectives.", "label": "poster"}
{"text": "In this work, the drawings collected from healthy individuals and people with PD were classified by RFC. The proposed method employed pencil drawings digitized from ordinary sheet of paper, making it very simple to be applied in the context of scarce financial resources. Despite the small number of images in the available data set (51 per class), the obtained results were satisfactory and accurate by discriminating drawings of healthy people from those with PD. HOG parameters were tested in default values (10x10 pixels per cell, 2x2 cells per block and 9 bins in the histogram with 0-180\u00b0 orientation) focus on good performance showed by Dalal and Triggs [4] and the HOG result was passed to the classifier. This is the first reported study considering the application of HOG estimates in combination with the RFC applied to the automatic classification of data obtained from people with PD. In the future, it will be necessary to obtain more image drawings and different shapes to increase the database and test more parameters. ACKNOWLEDGEMENTS DISCUSSION AND CONCLUSION Parkinson\u2019s disease (PD) is a neurological disorder that is progressive and causes losses of dopaminergic neurons from the substantia nigra, a region in the human brain. The decrease of dopamine in this area implies the worsening of motor symptoms such as tremors, bradykinesia, rigidity, gait impairment, and non-motor symptoms such as depression, loss of cognitive functions, sleep problems and nerve pain [1]. PD affects 1% of the world\u2019s population aged 60 years and over, and despite scientific advancement, the disease remains incurable. The diagnosis of PD is complex, with a seasoned specialist being necessary to make it [1, 2]. Tremors are a common symptom in PD and it can be classified into many types: resting tremor, postural tremor, kinetic, essential, cerebellar, and others. Each type manifests in different situations and frequency ranges [3]. This work proposes to classify images of handwritten drawings collected from healthy individuals and people with PD. The identification and discrimination of motor symptoms in PD is a fundamental step in the diagnosis and follow-up of the disorder. INTRODUCTION 1. de Lau LM, Breteler MM (2006) Epidemiology of Parkinson\u2019s disease. Lancet Neurol 5:525\u2013535. doi: 10.1016/S1474-4422(06)70471-9 2. Cancela J, Mascato SV, Gatsios D, et al (2016) Monitoring of motor and non-motor symptoms of Parkinson\u2019s disease through a mHealth platform. In: Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. IEEE, pp 663\u2013666 3. Andrade AO, Pereira AA, Almeida MFS de, et al (2013) Human Tremor: Origins, Detection and Quantification. In: Andrade AO (ed) Practical Applications in Biomedical Engineering. InTech, Croatia 4. Dalal N, Triggs B (2018) Histograms of Oriented Gradients for Human Detection. In: 2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR\u201905). IEEE, pp 886\u2013893. The present work was carried out with the support of the National Council for Scientific and Technological Development (CNPq), Coordination for the Improvement of Higher Education Personnel (CAPES \u2013 Program CAPES/DFATD- 88887.159028/2017-00) and the Foundation for Research Support of the State of Minas Gerais (FAPEMIG-APQ-00942-17). A. O. Andrade, A. A. Pereira and M. F. Vieira are a fellow of CNPq, Brazil (304818/2018-6, 310911/2017-6, and 306205/2017-3). RESULTS REFERENCES The Federal University of Uberl\u00e2ndia\u2019s Research Ethics Committee approved the research under the number 07075413.6.0000.515. In the study, 51 images were collected from each group, i.e., healthy individuals and people with PD. A total of 102 images were available. MATERIALS AND METHODS Group Total Sex (F/M) Age (years) Health 12 8/4 60.08 \u00b1 6.13 PD 15 7/8 65.33 \u00b1 9.17 Fig. 1. (A) Samples of handwritten drawings collected from people with Parkinson\u2019s disease (PD) and healthy individuals (H); (B) Pre-processed ima", "label": "poster"}
{"text": "According to Google: How does Google Images see and show climate change and biodiversity loss? Data collection Data curation Visualisation and Analysis The Google Images search engine is probably the most important online gatekeeper of visual culture worldwide, with over two billion searches conducted on the platform every day. Despite the platform\u2019s importance, there is a scarcity of analyses on how Google determines the visibility of images within its search rankings. For example, is \u201cauthority\u201d determined in a similar way to its textual web search results? Or do computer vision techniques offer new criteria for promoting images and the websites that host them? This research project focused on the visualisation of [climate change] and [biodiversity loss] by building a dataset of country-specific search rankings from Google Images. We scraped data from six different countries, selected for their political and geographic diversity in relation to the environment: Australia, Netherlands, Nigeria, China, Mexico and Brazil. We built on findings from a 2019 DMI Summer School project, Climate Image Spaces, that suggested Google Images shows a dehumanised visual vernacular of climate change dominated by landscapes, charts and the Earth. Google Images has a homogenising effect on the visual vernaculars of both climate change and biodiversity loss. For climate change, generic representations of climate change dominate. In particular, a small number of \u201ciconic\u201d stock images are highly ranked across the different countries. Many of these images have a half and half \u201cleft/right\u201d layout suggesting the current, often dystopian, situation on the left, with a more hopeful utopian future on the right (occasionally this implied temporality is reversed). Examples of these images include \u201chand in earth\u201d, \u201clandscape\u201d and \u201ctree\u201d. For biodiversity loss, there is also homogeneity, although with some greater country-specific diversity. Stock imagery is less dominant, but half and half images remain important, such as \u2018forest as lungs\u2019. Although biodiversity loss covers many different aspects of environmental degradation, the imagery focuses almost exclusively on deforestation. Images appear to be ranked on whether they \u201caccord\u201d with Google\u2019s envisioning of climate change as time-less, place- less, human-less and cause-less. Websites not according to Google\u2019s visions of climate change and biodiversity loss are unlikely to be ranked highly by Google Images. We used a Python script and VPNs to collect the top 50 images associated with [biodiversity loss] and [climate change] on Google Images for six countries: China, Brazil, Netherlands, Nigeria, Mexico. This resulted in a corpus of 300 images for each search term. We identified the most similar/mobile images across datasets using Google Cloud Vision, Clarifai and Memespector. Using vision APIs we identified labels and web entities associated with the images, which we used to gain a deeper understanding of the logic underpinning the sorting of images. Manual coding was then used to identify specific types of images which were not characterised by Google or Clarifai labels (e.g. half and half images, degraded forests). Using semiotics to inform our analysis manual coding served to differentiate between identical and similar images. Country specific datasets were then merged into a master spreadsheet for each term and used to identify top 10 images. We repeated the same process and expanded our data collection using the Search Engine Scraper developed by the DMI to scrape the top 10 ranking websites of Google. We extracted web domains and used the Triangulate tool to compare Google's Search and Images results in each country. Data and protocols were collated in a shared Google Drive folder. A range of tools were used for data collection, in particular a Python script and DownThemAll, and for data analysis: Clarifai, Cloud Vision, Memespector, Imagesorter, Rawgraph and Gephi. Data was centralised in csv for", "label": "poster"}
{"text": "MICROBIAL AND ANTIMICROBIAL RESISTANCE GENE DIVERSITY IN EXTRACELLULAR AND TOTAL DNA ACROSS RURAL ECOSYSTEM BARRIERS IN EUROPE Oliven\u00e7a D1, Cabal A2, Tenson T3, Hassan M4, Manageiro V1, Dias E1, Rosado T1, K\u00f5iv V3, Kisand V3, Rab G5, Jeremejeva J6, Telling K3, Arbo K3, Chambers M4, Laragione R4, Voit E7, Draho\u0161ov\u00e1 Z8, Ko\u0159\u00ednkov\u00e1 M8, Woegerbauer M9, Ruppitsch W2, Cani\u00e7a M1, de Menezes A10 1National Institute of Health Dr. Ricardo Jorge \u2013 Lisbon, Portugal; 2Institute for Medical Microbiology and Hygiene, AGES-Austrian Agency for Health and Food Safety, Vienna, Austria; 3University of Tartu, Estonia; 4University of Surrey, Guildford, United Kingdom; 5Vienna University of Technology, Vienna, Austria; 6Estonian University of Life Sciences, Estonia; 7Georgia Institute of Technology and Emory University, Atlanta, USA; 8The National Institute of Public Health, Prague, Czech Republic; 9 Division for Risk Assessment, Data and Statistics, AGES - Vienna, Austria; 10National University of Ireland Galway, Galway, Ireland Aim: To determine the microbial community composition and antimicrobial resistance genes (ARGs) diversity in total and extracellular DNA in agricultural ecological compartments in Europe. This work is part of the OHEJP FED-AMR consortium, which aims to investigate the role of free extracellular DNA (exDNA) in the spread of AMR genes across ecosystem barriers via bacterial transformation. Methods: Sampling was carried out in Austria, Portugal Czech Republic, Estonia, UK and Ireland. Both total (tDNA) and extracellular DNA (exDNA) were extracted along one crop-growing season, and sequencing of the 16S rRNA genes and ARG-capture coupled with metagenomic sequencing were performed. Results: The 16S and ARGs sequencing results were obtained for 511 samples, including 258 exDNA samples. Naturally- transformable bacteria, capable of incorporating exDNA into their cells, were present in the samples. Conclusions: Further analyses will link microbiome and ARGs with contaminants, antibiotics, heavy metals and trace elements to better understand the importance of exDNA as a vector for AMR spread in agricultural ecosystems. WILD ANIMALS (faeces) PIG BARN (faeces, waste) Manure CROP FEED (on site/imported SOIL (different crops, fertilization WATER (field drainage) FARMERS (swab samples, faeces) WATER (surface, river, irrigation) WASTEWATER TREATMENT PLANT WATER (drinking, ground) Figure 2. Ordination plot of microbial diversity. Ecological compartment influenced microbiome and ARG diversity. Figure 3. ARG composition of exDNA of wastewater sludge from Ireland. Sludge exDNA had a large number of ARGs, showing their potential for ARG spread in the environment Figure 1. Possible routes of ARG spread across ecosystem barriers and targeted ecological compartments in FED-AMR Acknowledgements: This work was supported by funding from the European Union\u2019s Horizon 2020 Research and Innovation programme under grant agreement No 773830: One Health European Joint Programme; FED-AMR project.", "label": "poster"}
{"text": "A brain can perform tasks more complex than the sum of the brain parts involved We measure this difference (Phi) Phi correlates well with fitness / evolution (Edlund 2011) Fitness implies minimally required Phi Only engineered or unrealistic systems have been measured Phi could be used to quantitatively diagnose brain states (Fig.1) Here we measure Phi of a detailed model organism interacting with a fully modelled physical environment There are several potential challenges Will the temporal effect of Phi be problematic? We expect a Minimum Phi Fitness effect. Is this true? Toward the Measure of a Brain J. Schossau, C. Adami - Department of Computer Science & Engineering - Michigan State University Conclusions The measure called Phi could be useful to aid basic research on cognition and consciousness or help doctors quantitatively diagnose states of mental existence. However, complexity of performing this measure mandates a controlled environment and neuron-precision measurements. We've shown the first application of this measure to a sufficiently realistic simulation of a highly detailed modelled forward locomoting C. elegans and realistic environment. This work is the first step toward making the detailed version of Phi measure a biological reality and we validate the model by comparison to previous work. Introduction 1 Used a detailed differential equation based neurological model of C. elegans forward locomotion by Jan Karbowski et al Results All double and single ablations collectively show the characteristic Minimum Phi Fitness effect (red line). The system performs similarly to other systems that are a product of evolution. There is no large temporal effect on measuring Phi in a real system, which was originally thought to be biggest problem. Phi as a measure of information integration can be useful in many other contexts, such as evolutionary computation. For instance, we're studying Phi's effect on evolvability concerning a primary fitness criterion. Another direct application of Phi which we're pursuing is to aid in developing technology to automatically detect breast cancer. Fig. 1 Consciousness is not on or off, but a gradient. Phi could help us quantitatively measure this gradient. (Noirhomme 2010) Brain death Coma VS MCS LIS Fig. 2 Original model by Karbowski. Continuoum of Consciousness Fig. 3 Recreated DiffEQ results. Muscle activations over time. Fig. 4 Ablated Neurons to test Phi measure and behavioral effect. 3 Created a fully 3-D virtual world and an articulated virtual worm body with muscles to enable environmental interaction driven by the mathematical neural model 2 Implemented this model as a computational simulation and recreated their results 4 Recorded neural activity as the worm wiggled through the environment, then calculated Phi from the recordings Fig. 4 Initial 3-D virtual worm. 5 Performed neural ablation experiments (knockouts) to validate experimental setup. We expected the resulting diversity of architectures to exhibit the Minimum Phi Fitness effect. (see Fig. 5) Fig. 5 Current 3-D virtual worm. Delta Distance Fig. 5 Minimum Phi Fitness effect 0 Delta Phi Each dot represents one replicate from all neural ablation experimental conditions. Some are single ablation and others are double ablations. The distribution shows that better task ability requires a minimum of ability to integrate information (phi) and suggests the system is a reasonable representation of an evolved decision-making network. (Edlund 2011) [ Jory @ msu . edu ] Thanks To BEACON \u2014 Paul Allen Foundation \u2014 ICER Methods", "label": "poster"}
{"text": "CLARIAH-DE Work Package 3 Skills Training and Promotion of Junior Researchers Goals For a research \ufb01eld that is characterised by rapid technical development, CLARIAH-DE has to include the promotion of data literacy necessary for the ef\ufb01cient use of this digital research infrastructure as part of its objective. To develop, consolidate and re\ufb01ne a common programme in this area, work package 3 set itself the following sub goals: Task and Co-Taskleaders: Fotis Jannidis (Institute for German Philology, W\u00fcrzburg University) Andreas Witt (Leibniz-Institute for the German Language, Mannheim) Centralised search For \ufb01nding recommended teaching and training materials of digital research tools, methods and approaches work package 3 developed a centralised service in close cooperation with work package 4. The Tutorial Finder is targeted at enabling: \u25cfstudents to acquire or deepen knowledge in self-study. \u25cflecturers to \ufb01nd materials to use in their teaching. \u25cfresearchers to acquire new methods, to discover new resources or to achieve international visibility of their material and research. \u25cfthe general public to get a quick and easy overview of available materials. Courses Work package 3 analysed abstracts on quantitative text analysis from Digital Humanities conferences to identify gaps in the range of courses. It closed remaining gaps by writing tutorials tailored to the needs of the target audience: \u25cfWord Embeddings \u2013 Machine Learning for NLP \u25cfLinear Algebra \u2013 Introduction for researchers from the Humanities and Cultural Sciences \u25cfStatistics \u2013 Overview of quantitative methods \u25cfDigital Editions \u2013 Work\ufb02ow for Digital Editions Promotion of junior researchers Training and promotion of junior researchers are based on durable teaching materials for interdisciplinary reach, targeted training courses with greater impact on speci\ufb01c disciplinary communities and individual support for junior researchers. Junior Researchers were enabled to participate in conferences relevant to their current research. Travel grant winners share their re\ufb02ections: \u25cfNadine Sutor: \u201eI know you from Twitter // #DHd2020\u201d \u25cfRamona Roller: DHd 2020 - \u201cWhat is a model and why do we need it?\u201d The CLARIAH-DE Tutorial Finder Analysis of 164 abstracts from Digital Humanities conferences Selected Events: \u25cf2019: European Summer University in Digital Humanities \u2192 \"Culture & Technology\" \u25cf2019: Topic Modeling Workshop \u2192 \"Topic Modelling. Hands-on Training and Discussion Session\" \u25cf2020: Poster presentation \u2192 \u201eAuthentic spoken data and applied conversation analysis as a resource for the improvement of communicative competence in healthcare\u201c at the \u2192 \u201eTeaching and Language Corpora Conference\u201c \u25cf2021: Lecture series on \"Digital Humanities \u2013 Theorie und Methodik \u2018Data Literacy and Digital Humanities\u2019\" Skills training of, individual support for and the promotion of junior researchers Cataloguing and re\ufb02ecting on the methods and tools used in the research \ufb01eld, with the aim of identifying remaining gaps. Consolidation of the activities from the previous projects into a joint service Re\ufb02ecting on the methods and tools used in the research \ufb01eld to identify and cloe remaining gaps Poster of the European Summer University, 2019 Twitter post for Dhd 2020", "label": "poster"}
{"text": "@ F A C E I TA rc t i c @ F A C E I TA rc t i c @ fa c e _i t _a rc t i c @ The F A C E -I T Pro j e c t www.face-it-project.eu FACE-IT has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement No 869154. @ No ra _D i e hl No r a D i e hl M a ri ne B o t a ny U ni ve rs i t y o f B re m e n ndi e hl@ uni -b re m e n. de Fig. 2 Experimental set-up using adult sporophytes of L. hyperborea. w = week: w0, w4, w8, w12 = experimental samplings Fig. 1 Dots mark the current distribution of L. hyperborea. Orange line marks AMAP borders. Will L. hyperborea be able to spread throughout the High Arctic under future climatic conditions? Photoperiod and temperature interactions drive the latitudinal distribution of kelps under climate change Nora Diehl1,2*, Philipp Laesekea, Inka Bartsch2, Margot Bligh1,3, Hagen Buck-Wiese3, Jan-Hendrik Hehemann1,3, Sarina Niedzwiedz1, Niklas Plag4,5, Ulf Karsten4,6, Tifeng Shan7 & Kai Bischof1 Background: Due to global rise of temperatures, recent studies predict an expansion of kelps to higher latitudes. One of these is the cold-temperate kelp Laminaria hyperborea. It has been shown in different single-factorial experiments to survive several months of cold temperatures and darkness. Therefore, it is striking that it has not yet spread throughout the high Arctic. Aim: Find strategies how L. hyperborea can to acclimate to past, present and future conditions in the Arctic. Introduction Laminaria hyperborea is a dominant and important European bioengineering species. As \u2018season anticipator\u2019, it grows at low temperatures and during the short days of winter and early spring. Long and polar day conditions have been shown to restrict its growth. To investigate the potential ability of L. hyperborea to invade high Arctic sites under future warming scenarios, we conducted a long- term multifactorial experiment using tissue of adult sporophytes from Pors\u00e1\u014bgguvuotna/Porsangerfjord, Finnmark, Northern Norway \u2013 a site close to its northernmost distribution margin. Material & Methods Physiological Results & Discussion We quantified the physiological conditions of L. hyperborea and biochemical metabolites, including storage carbohydrates, under polar night, polar day and long day conditions at 0, 5 and 10\u00b0C. Cold temperatures in combination with light stressed L. hyperborea, while long polar night conditions did not harm it at any temperature (Fig. 1). Still, samples gained weight under light treatments, due to their physiological modulation to accumulate carbohydrates as reserves for winter (Fig. 2). The physiological results strongly indicate that L. hyperborea is restricted only by the long cold light periods in the Arctic and will benefit from increasing temperatures in summer. The warmer the Arctic becomes, the better L. hyperborea will cope with polar day. New species can have multiple consequences on the functioning of marine ecosystems. The stipe of L. hyperborea is rich in epibiont assemblages, which act, for example, as food source for associated mobile species, such as fish and sea urchins. Hence, the spread of L. hyperborea in the High Arctic will have cascading effects on the entire ecosystem. \u00a9Uli Kunz References L\u00fcning K (1986). New frond formation in Laminaria hyperborea (Phaeophyta): A photoperiodic response. Schaffelke B & L\u00fcning K (1994). A circannual rhythm controls seasonal growth in the kelps Laminaria hyperborea and L. digitata from Helgoland (North Sea). Scheschonk L, Becker S, Hehemann J, Diehl N, Karsten U, Bischof K (2019). Arctic kelp eco-physiology during the polar night in the face of global warming: A crucial role for laminarin. Acknowledgements The authors are grateful to T. Wernberg, K. Filbee-Dexter and their diving team for collecting the kelps. Thank you to A. Wagner for his support in the experimental procedure and to B. Iken for the support in the laboratory. 1 Faculty of Biology and Chemistry & MARUM, University of Bremen, D", "label": "poster"}
{"text": "Viewing FSL results with SPM and vice versa Thomas Maullin-Sapey1, Peter Williams2, Guillaume Flandin3, Thomas E. Nichols1,4, Camille Maumet4 1. Department of Statistics, University of Warwick, Coventry, UK 2. Department of Mathematics, University of Warwick, Coventry, UK 3. Wellcome Trust Centre for Neuroimaging, UCL Institute of Neurology, London, UK. 4. WMG, University of Warwick, Coventry, UK Acknowledgments: We would like to acknowledge the work of all the INCF task force members as well as of many other colleagues who have helped the task force. We are particularly indebted to M. Abrams and the INCF secretariat staff. We also acknowledge the long-standing support of DDWG activities by the BIRN (NIH 1 U24 RR025736-01), and the Wellcome Trust for support of (CM, TEN). Fig. 1. Viewing the results of the same group fMRI study with SPM and FSL. The corresponding NIDM-Results pack is available at: http://neurovault.org/collections/1692/fsl_group_ols.nidm. Introduction A growing number of efforts are emerging in the neuroimaging community to increase reproducibility of research findings (e.g. [1,2]). In an attempt to facilitate publishing of neuroimaging data and metadata, the NeuroImaging Data Model (NIDM) defines a set of specifications based on semantic web technologies. The NIDM-Results specification was recently introduced, providing a machine-readable representation of mass univariate statistical results, including extensive metadata and key images summarising the findings [3]. NIDM-Results packs can be generated from SPM [5] and FSL [6]. However few tools exist to read and display NIDM-Results. Here, we introduce two NIDM-Results viewers, one each oriented for users accustomed to SPM and FSL, two of the most widely-used neuroimaging analysis softwares [7]. Results Conclusion SPM-style viewer: https://github.com/incf-nidash/nidmresults-spmhtml, FSL-style viewer: https://github.com/incf-nidash/nidmresults-fslhtml, NIDM-Results specification: http://nidm.nidash.org/specs/nidm-results.html. Getting started with NIDM: http://nidm.nidash.org/getting-started/. We hope that the viewer will facilitate the adoption of the NIDM-Result format for sharing of statistical results in the neuroimaging community as well as interoperability across software packages. This work is part of a growing ecosystem of tools for NIDM and it is our intention to develop more applications to further to increase the practical utility of NIDM-Results. Other projects also include the creation tools for meta-analysis of neuroimaging data. [1] Gorgolewski, Front Neuroinform. 2015 [2] Poldrack Front Neuroinform. 2013 [3] Maumet Scientific Data. 2016 [4] http://www.equator-network.org [5] Penny Academic press. 2011 [6] Jenkinson Neuroimage. 2012 [7] Carp Neuroimage. 2012 [8] https://rdflib.readthedocs.io/ [9] http://neurovault.org/collections/1692/ [10] Pauli et al. Front Neuroinform. 2016 References We acknowledge the work of all INCF task force members as well as the Wellcome Trust for support of CM and TEN. Acknowledgments Usage -style view -style view Publication Unthresholded statistic maps All cluster & peak locations Machine-readable metadata NIDM-Results Selected peak locations Figure (selected slices) Thresholded statistics Installation NIDM-Results Useful links addpath(PATH_TO/spm12) addpath(PATH_TO/nidmresults-spmhtml) 1. Download SPM-style viewer from https://github.com/incf-nidash/nidmresults-spmhtml 2. Update the Matlab path pip install git+git://github.com/incf-nidash/nidmresults-fs lhtml.git 1. Install the FSL-style viewer using pip nidm_results_display(\u2018fsl_group_ols.nidm.zip\u2019) View a NIDM-Results pack with: nidmviewerfsl fsl_group_ols.nidm.zip", "label": "poster"}
{"text": "Optimally weighted ensemble for sub-seasonal forecasting Julien Brajard1\u2217 Fran\u00e7ois Counillon1,2 Yiguo Wang1 Madlen Kimmritz3 1NERSC, Bergen, Norway 2Geophysical Institute, University of Bergen, Norway 3AWI, Bremerhaven, Germany Introduction 1 Seasonal forecasts are issued as the arithmetic mean (equal weights: EW) of an ensemble of simulations initialized by assimilating observations. 2 During the operational production of the forecast (considering the bu\ufb00er-time needed to ensure timely delivery), new unused observations can be available (typically a week). Objective De\ufb01ning an optimal weighted average (OW) that can use independent data to enhance the skill of the forecast on a subseasonal time scale with respect to equal weighted averages (EW). Setup of the experiment \u2022 Forecasts x: The Norwegian Climate Prediction Model (NorCPM) is providing skillful seasonal forecasts (Wang et al. 2019). A 60 member ensemble reanalysis reanalysis has been recently produced by assimilating monthly sea-surface temperature (SST) and T-S pro\ufb01le data with the ensemble Kalman \ufb01lter. Retrospective hindcasts of 60 members - initialised from the reanalysis - have been produced for the period 1985 to 2010 with 4 start dates per year. \u2022 Observation y: A weekly NOOA sea-surface , optimally interpolated (Reynolds et al. 2002) after the analysis month is used to determine the weights. Estimation of the Optimal Weights (OW) For a forecast xn of index n (1 \u2264n \u2264N, N is the size of the ensemble) and a grid point i, the weight is determined by: wn,i \u221dexp \u22121 2(\u03c1i \u25e6d)TR\u22121(\u03c1i \u25e6d) ! , where \u2022 d = (y \u2212xn) \u2022 \u03c1i is a localization vector whose elements are: \u03c1ik = f (d(i, k)/L) , \u03c1ik = 0 if d(i, k) > L \u2022 R = (\u03bbo)2Eobs, is the observation error. Eobs is the diagonal error provided with the NOAA product and \u03bbo is an in\ufb02ation factor. Illustration with a Lorenz model The algorithm has been tested using a Lorenz 96 model with a observation at 0.2 time after the analysis time. \u2022 The forecast skill (in RMSE) is improved until a time of 1 (> 3 Lyapunov time) \u2022 The error of the OW mean at the observation time is comparable to the error of the analysis (initial time) Results The validation is performed on the sea-surface temperature by comparing with future observations. All the con\ufb01- dence intervals and signi\ufb01cativity of the results are computed by bootstrapping with 100 samples. Figure: Global correlation space- and time-wise as a function of the lead month for the optimal weights (OW) and the equal weights (EW) hindcast. \u25b6The optimal weights hindcast has higher skill up to 2-3 leading months. Figure: Gobal correlation space-wise for a two monhts leading time as a function of the date for the optimal weights (OW) and the equal weights (EW) hindcast. The \ufb01lled circles (resp. un\ufb01lled) correspond to the dates where the di\ufb00erences are signi\ufb01cant (resp. not signi\ufb01cant). \u25b6The improvement is found for the whole period. Figure: Time-wise correlation 1985-2010 at a two months leading time for the hindcast computed with equal weights (the baseline on the left panel) and with optimal weights (the center panel). The right panel shows the di\ufb00erence between the weighted hindcast correlation and the equal weights hindcast correlation, positive values indicating that optimal weights have improved the correlation. \u25b6The improvement is consistent on the whole domain but has di\ufb00erent magnitude depending on the region. Regional improvement Correlation at a two month leading time globally and for di\ufb00erent regions Region Correlation OW EW Global 0.50 0.44 ENSO 0.93 0.90 Bar 0.50 0.33 Norw 0.63 0.63 \u25b6Some regions with low skill using EW have better skill with the optimal weights (OW), e.g. the Barents Sea. Conclusion \u25b6Seamless update of the forecast between two oper- ational forecast releases with the arrival of fresh data \u25b6Improvement up to a 3 months lead-time \u25b6No need to recompute the forecast \u25b6Little sensitivity to the hyperparameter tuning Sensitivity Two hyperparameters need to be tuned to det", "label": "poster"}
{"text": "Introduction: The 2022 crisis has significantly changed European countries' approach to energy security and demonstrated the need to become independent from Russian energy imports. It has also revived the discussion on accelerating renewable energy changes to increase the share of green energy in the total energy balance of the associated countries. The main goal of the Research: primary analysis of selected conditions for energy security of European Union countries, in the context of turbulence on energy markets in Europe after the year 2022, using the non-parametric Wilcoxon signed-ranks test Application: desirability, possibility, and necessity of building an inter-state model, which can optimize energy flow management based on the principles of sustainable development, influencing the increase of energy security in Europe. Research hypothesis: The crisis of 2022 significantly changed the approach to optimizing energy flows Variables included in research: Total Energy Supply, which includes all the energy produced in or imported to a country, minus that which is exported or stored. It represents all the energy required to supply end users in the country. Energy trade balance, which is the difference between Energy import and export Change in energy balance in the European Union after 2022 dr Beata Szetela, dr hab. Grzegorz Mentel, prof. PRz \u2013 faculty of Management, Rzeszow University of Technology, Poland Prof. Najiba EL AMRANI EL IDRISSI, Faculty of Science and Technology, USMBA, Fez, Morocco Energy mix changes in UE between 2000 - 2022 \uf0fcSystematic decline in the amount of coal used \uf0fcIncreasing role of energy obtained from renewable energy sources \uf0fcReduction of the natural gas demand \uf0fcIncrease in the total European Energy imports by 3% and decline of exports by 0,5% between 2021 and 2022 \uf0fcindependence from energy supplies from Russia- Results \uf0fcIn the case of coal, there are no significant changes in its share in the total energy mix, especially compared to the previous four years, when a systematic decline in the amount of coal used was observed. \uf0fcThere are statistically significant differences in wind- and solar-based produced Energy, towards significant increases in renewable energy production \uf0fcThere are significant differences in the amount of energy imported among developed and emerging European countries. In 2022, compared to 2021, the increase in imports among developed countries ranged from 2% in Belgium to 22% in Austria, while in developing countries the largest increase was recorded in Slovenia, where it amounted to 19%. All countries that recorded a decline in fuel imports in 2021 saw a significant increase in imports in 2022, which was undoubtedly due to the turmoil in energy markets caused by Russia's attack on Ukraine. The research leading to these results has received funding from the project titled \"Cluster for innovative energy\" in the frame of the program \"HORIZON-MSCA-2022-SE-01\" under the Grant agreement number 101129820 29.02-01.03. 2024 Szczecin V Edycja Mi\u0119dzynarodowej Konferencji Naukowo-technicznej \"Energia Nowoczesnych Miast\" https://energia.usz.edu.pl/", "label": "poster"}
{"text": "Resistant Starch 5: A Novel Approach to Reducing Postprandial Glycaemia and Lipaemia \u2022 Factors that affect the formation of RS5 include temperature, time, stirring speed, size of stirring rod \u2022 RS5 can be produced with small quantities of fat/oil added to starchy food 1 WHO (2018). Diabetes. World Health Organisation. Online. Available from: https://www.who.int/news-room/fact-sheets/detail/diabetes [Accessed 27 April 2020]. 2 Saeedi, P. et al., (2019). Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Research and Clinical Practice. 157; 107843. 3 Lehmann, U. and Robin, F. (2007). Slowly digestible starch - its structure and health implications: a review. Trends in Food Science and Technology. 18; pp. 346 \u2013 355. 4 Fuentes-Zaragoza, E., Riquelme-Navarrete, M. J., S\u00e1nchez-Zapata, E., and P\u00e9rez-\u00c1lvarez, J. A. (2010). Resistant starch as a functional ingredient: A review. Food Research International. 43; pp. 931 \u2013 942. \u2022 In 2016, diabetes caused about 1.6 million deaths, and the global prevalence of diabetes in 2019 was estimated to be 9.3%, projected to rise to 10.2% by 2030. \u2022 Cardiovascular diseases (CVDs) are one of the common complications of diabetes which may lead to early death. \u2022 Diabetes is a disease that occurs when the blood glucose is too high. It has also been identified as a secondary cause of lipaemia. \u2022 Lipaemia is the presence of an abnormally high concentration of fat in the blood. Figure 1. Pictorial illustration showing the formation of RS5 (amylose-lipid complexes). \u2022 The nutritional quality of starch depends on how it has been processed and the major physiological effect of starch is the release of glucose, as a source of energy for the body. \u2022 Starch can be processed to form a kind of dietary fibre called resistant starch (RS). \u2022 RS is the fraction of starch that is not broken down to glucose in the small intestine within 120 minutes of being consumed. It is therefore fermented in the large intestine and serves as a source of fibre. \u2022 Types of RS classified based on their physical and chemical characteristics: RS1 - RS5 \u2022 Objective: To investigate the formation and digestion process of resistant starch 5 \u2013 RS5 (amylose-lipid complexes). Background Introduction Conclusion Method Results References How does the consumption of resistant starch 5 (amylose-lipid complexes) affect the levels of glucose and fat in the blood? A. O. Adewuni*, T. Grassby, M. D. Robertson School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU27XH, UK *a.adewuni@surrey.ac.uk Research Question Study 1 \u2022Production and characterisation of RS5* Study 2 \u2022In vitro digestion of RS5 - Simulated gastro- intestinal digestion Study 3 \u2022In vivo study \u2013 Human study Figure 2. Percentage complexing index with different ratios of palmitic acid and gelatinised starch. Proposed Impact \u2022 To proffer recommendations on the use of RS5 as a functional food ingredient in the management and subsequent treatment of illnesses such as diabetics and lipaemia \u2022 To promote healthier nutrition and lifelong health Discussion \u2022 Complexing Index (CI) ranged from 41% to 55% for 1:1 to 1:24 ratios of palmitic acid and gelatinised starch. \u2022 In reality (oil:starch): 91% 4% \u22481:23 \u2022 High percentage complexing index shows high values of RS5 *Note: This poster presents the work I have done so far (study 1 only). No information on study 2 and 3.", "label": "poster"}
{"text": "O projeto OSTrails visa contribuir para a melhoria dos processos e instrumentos de planeamento, monitoriza\u00e7\u00e3o e avalia\u00e7\u00e3o dos resultados de investiga\u00e7\u00e3o cient\u00ed\ufb01ca. A operacionaliza\u00e7\u00e3o dos seus objetivos vai decorrer trabalhando com v\u00e1rios parceiros nacionais e tem\u00e1ticos, com vista \u00e0 otimiza\u00e7\u00e3o da infraestrutura existente e estabelecendo liga\u00e7\u00f5es com as partes envolvidas no ecossistema cient\u00ed\ufb01co europeu. Desa\ufb01os Abordagem Interoperabilidade insu\ufb01ciente nas diferentes fases de investiga\u00e7\u00e3o. Sistemas de informa\u00e7\u00e3o acad\u00e9mica n\u00e3o interoper\u00e1veis ou reduzida harmoniza\u00e7\u00e3o das melhores pr\u00e1ticas adotadas. Incerteza quanto ao cumprimento dos princ\u00edpios FAIR e das pr\u00e1ticas de PGD. Mecanismos insu\ufb01cientes de monitoriza\u00e7\u00e3o. Diferentes n\u00edveis de maturidade de Ci\u00eancia Aberta, FAIR e EOSC. Pilotos Para de\ufb01nir, criar, validar e avaliar as suas atividades e resultados, o projeto vai pilotar a ado\u00e7\u00e3o dos seus desenvolvimentos, contando com a colabora\u00e7\u00e3o de v\u00e1rias institui\u00e7\u00f5es, estando previstos 15 pilotos nacionais e 9 pilotos tem\u00e1ticos, entre as quais a Universidade do Minho e a Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia. Contributos Reduzir as barreiras na ado\u00e7\u00e3o dos princ\u00edpios FAIR nas diferentes fases de investiga\u00e7\u00e3o; melhorar a avalia\u00e7\u00e3o da investiga\u00e7\u00e3o atrav\u00e9s de um sistema de investiga\u00e7\u00e3o interligado. Principais resultados Planeamento: melhorar a e\ufb01ci\u00eancia dos Planos de Gest\u00e3o de Dados, transformando-os em recursos interligados e acion\u00e1veis por m\u00e1quina. Monitoriza\u00e7\u00e3o: estabelecer um ecossistema aberto, interoper\u00e1vel e de elevada qualidade de sistemas de informa\u00e7\u00e3o de conhecimento cient\u00ed\ufb01co, bene\ufb01ciando da implementa\u00e7\u00e3o dos princ\u00edpios dos dados FAIR. Avalia\u00e7\u00e3o: disponibilizar ferramentas de avalia\u00e7\u00e3o dos princ\u00edpios FAIR, com vista a obter m\u00e9tricas acion\u00e1veis por m\u00e1quina integradas nas ferramentas que apoiam cada uma das fases do ciclo de vida de investiga\u00e7\u00e3o. Face a estes desa\ufb01os, prop\u00f5e-se a otimiza\u00e7\u00e3o do cumprimento dos princ\u00edpios FAIR, interconectividade e automatiza\u00e7\u00e3o dos sistemas, nas fases de planeamento, monitoriza\u00e7\u00e3o e avalia\u00e7\u00e3o da investiga\u00e7\u00e3o. Autores: Andr\u00e9 Vieira, Paula Moura, Pedro Pr\u00edncipe, Ant\u00f3nia Correia Universidade do Minho Rumo ao planeamento, monitoriza\u00e7\u00e3o e avalia\u00e7\u00e3o dos resultados de investiga\u00e7\u00e3o cient\u00ed\ufb01ca", "label": "poster"}
{"text": "a) b) c) Filling proces: pressure profiles 0 50000 100000 150000 200000 250000 Mean Pressure (Pa) -24 -20 -16 -12 -8 -4 0 4 8 12 16 20 Time (s) Mean Pressure (Pa) Experimental (-) (2) Air (1) Premixed Air+Fuel P = 0,368 bar 0,184 bar CH4 + 0,184 bar Air up to target pressure Ptarget = 2,28 bar \u03b6 Geometry of a combustion chamber Mesh Geometry simplification Air test simulation Initial and boundary conditions Sim. pressure profile Exp. pressure profile Inputfroman air test Dead volume adjustment Non-knocking combustion simulation Initial and boundary conditions Exp. pressure profile Sim. pressure profile \u2018Combustion model calibration\u2019 Knocking combustion simulation Initial and boundary conditions Self-ignition occurence Self-ignition occurence \u2018Knock model calibration\u2019 Dead volume: 70 cm of a pipe, closed 0 1e+06 2e+06 3e+06 4e+06 5e+06 6e+06 7e+06 8e+06 9e+06 1e+07 Mean Pressure (-) Experiment Simulation Dead volume: 20 cm of a pipe, closed 0 1e+06 2e+06 3e+06 4e+06 5e+06 6e+06 7e+06 8e+06 9e+06 1e+07 Mean Pressure (Pa) Simulation Experiment \u03bb \u03bb \u03bb=0,52 EQR=1,924 \u03bb=1,29 EQR=0,775 \u03bb=1,08 EQR=0,928 5.5 mm/s Velocity: EQR/\u03bb: \u03bb Pressure profile: dead vol. adjusted based on Airtest 415 0 2e+06 4e+06 6e+06 8e+06 1e+07 1.2e+07 1.4e+07 1.6e+07 Mean Pressure (-) 500 525 550 575 600 625 650 675 700 Crank Angle (-) Experimental (-) Simulated, SF 1.4 (Pa) Simulated, SF default (-) Pressure profile: dead volume tuning... 0 2e+06 4e+06 6e+06 8e+06 1e+07 1.2e+07 1.4e+07 1.6e+07 Mean Pressure (-) 500 525 550 575 600 625 650 675 700 Crank Angle (-) Exp. (aligned) (-) dead_volume (-) real_dead_vol_adj_pos_all_t (-) ..._tuned_comb_model (-) real_dead_vol_all_time (-) \u03bb \u03bb \u03bb Dead volume: 70 cm of a pipe, closed 0 1e+06 2e+06 3e+06 4e+06 5e+06 6e+06 7e+06 8e+06 9e+06 1e+07 Mean Pressure (-) 500 520 540 560 580 600 620 640 660 Crank Angle (s) Experiment Sim. adjusted piston profile Sim. org. piston profile Volume profile 0 0.0001 0.0002 0.0003 0.0004 0.0005 0.0006 0.0007 0.0008 0.0009 0.001 Total Volume (m^3) 500 520 540 560 580 600 620 640 660 Crank Angle (deg) Total Volume (m^3) org. piston (m^3) Total Volume (m^3) adjusted piston (m^3) Pressure profile: dead volume tuning... 0 2e+06 4e+06 6e+06 8e+06 1e+07 1.2e+07 1.4e+07 1.6e+07 Mean Pressure (-) 500 525 550 575 600 625 650 675 700 Crank Angle (-) Exp. (aligned) (-) real_dead_vol_all_time (-) kf 0.85 (-) kf 0.75 + piston min 0.5 mm (-)", "label": "poster"}
{"text": "*L. Graziani[1], B. Ciardi[2], M. Glatzle[2], M. B. Eide[2], M. C. Orofino[1], S. Gallerani[1] [1] Scuola Normale Superiore di Pisa, Pisa, Italy [2] Max Planck Institute for Astrophysics, Garching bei Muenchen, Germany Massive black holes in evolving galaxies: from quasars to quiescence June 25-29, 2018 Institut d'Astrophysique de Paris (IAP), Paris - France X\u00adrays ionization and heating by high\u00adredshift quasars Here we discuss the impact of quasars (QSOs) on the ionization and heating of host and field galaxies and on the intergalactic medium (IGM), by showing the results of radiative transfer simulations accounting for X\u00adrays and secondary electrons. By adopting a multi\u00adscale approach (100 h\u00ad1 / 25 h\u00ad1 / 1 h\u00ad1 cMpc boxes) we study the importance of feedback in different environments and the impact on observables present at different scales. The role of QSO in the general context of a full reionization simulation [1\u00ad2] and their relative contribution in the evolution of the first Gyr of our Universe is addressed in the first box. The second box considers a single QSO HII region in a case matching a ULAS J1120+0641\u00adlike QSO. Implications for the HII region properties are also discussed [3]. Finally, new small scale simulations accounting for X\u00adrays triggered photo\u00addissociation regions and metal ions are introduced in the last box [5\u00ad6\u00ad7]. Abstract Large scale reionization: impact of different sources Figure 1: 3D visualization of the HII, HeII and HeIII fractions in the QSO environment, as produced by both the central QSO and the surrounding galaxies with full UV and X-ray physics [1]. The images refer to a time tQ = 107 yr after the QSO has been turned on at z = 10. The simulation box is 50h-1 cMpc. Large scale reionization is dominated by the concerted impact of different sources. Galaxies drive the process during H-reionization, while QSOs create peculiar high-redshift environments and drive He-reionization [1,2]. Figure 2: Maps of temperature at z = 10 for galaxies only models with different assumptions of escape fractions ( GAL*), and galaxies+QSO models (GAL*+QSO) with UV and X-Rays [1]. Galaxies start to reionize the IGM at z = 15, while the QSO is turned on at z = 10 with a lifetime of 107 yr. The maps have a side length of 50h-1 cMpc and the width of the slice is 195h-1 ckpc. The galaxy and QSO H II (He III) I-front is shown as green and blue solid (dotted) contour, respectively. Figure 3: Maps in the plane of the first QSO at z = 12. Columns indicate different combinations of source types [2]. The upper rows show either HII or T, while the lower rows show the difference with respect to the first panel (stars only case). Simulation Box 100h-1 cMpc [3]. [1] Kakiichi, K.; Graziani, L.; Ciardi, B.; Meiksin, A.; et al., 2015, MNRAS, 468, 3 [2] Eide, M. B.; Graziani, L.; Ciardi, B.; Feng, Y.; et al., 2018, MNRAS, 476, 1 [3] Khandai, N.; Di Matteo, T.; Croft, R.; Wilkins, S.; et al., 2015, MNRAS, 450, 2 [4] Graziani L.; Ciardi B.; Glatzle, M., 2018, MNRAS, in press (DOI:10.1093/mnras/sty1367) [5] Barai, P.; Gallerani, S.; Pallottini, A.; Ferrara, A.; et al., 2018, MNRAS, 473, 3 [6] Graziani, L.; Maselli, A.; Ciardi, B., 2013, MNRAS, 431, 1 [7] Orofino, M. C.; Graziani, L.; Gallerani, S., et al., 2018, MNRAS, in prep. [8] Graziani, L.; Gallerani, S.;Orofino, M. C., et al., 2018, MNRAS, in prep. Reference Local scale: QSO host and field galaxies Figure 6: Slice cut of the simulation in [5] showing the gas number density (left panle), the velocity field ( middle) and the temperature field (right) in a plane intercepting both the QSO outflow and the galaxy host. The box is 1h-1 cMpc and it is shown in cell units (1 cell = 0.78 kpc physical). The simulation redshift is z=6. Figure 8: Star formation rate (SFR) evolution in redshift of a massive halo invested by the QSO outflow. Two feedback configurations are shown: spherical and conical. The evolution of star formation is strongly impacted by different modeling of QSO outflow [7", "label": "poster"}
{"text": "M F U DATE: Thursday 3 December TIME: 6.30-8pm LOCATION: The Alderman (upstairs) 134 Lygon St East Brunswick FORMAT: 45 minute panel presentation 45 minute open discussion From the romance of fairy-tales to the sexual appeal of popular culture, the characterisation of girlhood in the Western media landscape presents a passive and commodified image of femininity in a hegemonic fashion. The development of new media technologies and the rise of consumer culture have increased anxieties surrounding the social identity and the corporeality of girls. How do girls interpret and negotiate these mainstream narratives? Is there room for alternatives? What can we learn from how girlhood has been defined in other times and cultures? Join ELODIE SILBERSTEIN (Monash University) in conversation with MICHELLE SMITH (Deakin University), SOFIA RIOS (Monash University) and FREYA BENNETT (founder of Tigress Magazine) as they problematise the idea of girlhood across borders and across time. FROM CINDERELLA TO TELENOVELAS NARRATIVES OF GIRLHOOD IN A GLOBALISED WORLD A PANEL DISCUSSION WITH ELODIE SILBERSTEIN, MICHELLE SMITH, SOFIA RIOS & FREYA BENNETT SPECIAL SEMINAR f i n d MELBOURNE FREE UNIVERSITY on twitter & facebook .org MELBOURNEFREEUNIVERSITY", "label": "poster"}
{"text": "Making Ice Penetrating Radar More Accessible A tool for \ufb01nding, downloading, and visualizing georeferenced radargrams within the QGIS ecosystem NSF: 2209726 PI: Laura Lindzey Abstract Ice Penetrating Radar has been a fundamental tool for understanding polar ice sheets since the \ufb01rst \ufb02ights in the 1960\u2019s. The US alone has spent many tens of millions of dollars on direct grants to enable the acquisition and analysis of radar data, and even more on related infrastructure and support costs. The QIceRadar project tries to make these critical datasets more FAIR. It will index data that is distributed across multiple international data centers (\ufb01ndability) and will provide a consistent interface to the many di\ufb00erent formats this data is published in (interoperability). We chose to build this functionality as a QGIS plugin because QGIS is already used by much of the polar community: Quantarctica and QGreenland have rapidly become indispensable data indices for researchers, making diverse data sets readily available. Thus, with no additional work on our part, QIceRadar will enable interpreting radargrams in context with many map- view datasets. Ice Penetrating Radar As an aircraft \ufb02ies above the ice sheet, the radar system emits VHF pulses. After each pulse, it records the intensity of re\ufb02ected echoes, which correspond to the air/ice surface, features within the ice, and the ice/bed interface. Radargram Interpretation Data Availability QIceRadar Left: QGIS screencap showing existing radargrams over Thwaites Glacier. Other active layers show the MODIS mosaic [1] included in Quantarctica [2] and hypothesized active lake outlines from [3]. Above: Segment of radargram THW/X63a [4] corresponding to the orange line in the map. The yellow dot in the map view corresponds to the location of the vertical red line in the radargram. [1] Scambos, Ted A., et al. \"MODIS-based Mosaic of Antarctica (MOA) data sets: Continent-wide surface morphology and snow grain size.\" Remote sensing of environment 111.2-3 (2007): 242-257. [2] Matsuoka, Kenichi, et al. \"Quantarctica, an integrated mapping environment for Antarctica, the Southern Ocean, and sub-Antarctic islands.\" Environmental Modelling & Software 140 (2021): 105015. [3] Smith, Benjamin E., et al. \"Connected subglacial lake drainage beneath Thwaites glacier, west Antarctica.\" The Cryosphere 11.1 (2017): 451-467. [4] Chu, W., Culberg, R., Hilger, A., Jordan, T., Schroeder, D., Seroussi, H., et al. (2021) \"Radar Sounding Observations of the Amundsen Sea Embayment, 2004-2005\" U.S. Antarctic Program (USAP) Data Center. unavailable unsupported supported Intensity Time since transmission Air Ice Rock Polar ice penetrating radar data is collected by over a dozen countries/research groups, all of which utilize di\ufb00erent data centers and formats. Both Antarctica and Greenland / the Canadian Arctic are included in our index, and our viewer will work with data formats from every major provider. Unfortunately, much of Bedmap 3\u2019s data [5] are not available as radargrams. Our project includes a database of all known polar ice penetrating radar datasets, provided as a geopackage, and a plugin that enables visualizing them in context with other map-view datasets. In the radargram above, there is likely a deep valley where the bed was not observed, so an ice \ufb02ow model based on smoothed interpreted horizons (shown in red) and observed surface velocities may not converge. Modeling subglacial drainage networks is also sensitive to this e\ufb00ect. AGAP A38b [6] Radargrams contain far more information than the pro\ufb01le and gridded ice sheet geometry that is currently readily available. In the radargram above, there is an additional bright re\ufb02ector above the bedrock re\ufb02ection. [7] interpreted this to be a buried ash layer, corresponding to historical volcanism in West Antarctic and enabling the eruption to be dated to 8 kya. THW/Y53a [4] ICP3/F56T03a [8] Englacial layers observed in radargrams can be traced between core sites, inf", "label": "poster"}
{"text": "Investment barriers in renewable energy in tourism industry enterprises dr Svitlana Bilan, Centre of Sociological Research, Poland dr Katarzyna Chudy-Laskowska, Department of Quantitative Methods, Faculty of Management, Rzeszow University of Technology, Poland dr Nawrot \u0141ukasz, Centre of Sociological Research, Poland Introduction Renewable energy is an alternative to traditional energy sources. Its use helps mitigate the negative effects of greenhouse gas emissions and reduce global warming. Poland is considered a promising market for investments in renewable energy sources, but it encounters a number of barriers in the process of achieving the goals related to their implementation, preventing or hindering their use, negatively affecting the development of this sector. They are analyzed both at the EU level and in individual Member States. The aim of the study is to identify barriers limiting investments in renewable energy sources, which makes it possible to limit or eliminate mistakes and bad decisions that prevent the development of this sector. The main barriers related to the development of renewable energy in Poland included: limited possibilities of financing investments by entrepreneurs, legal regulations, administrative and procedural difficulties, as well as problems with the operation of transmission networks. It is also worth mentioning the barriers on the part of people related to the lack of knowledge, information about sustainable energy carriers, the possibility (willingness) to use them, related problems, benefits, etc. The research included entrepreneurs who use renewable energy technology (140 - 12%) and entrepreneurs who did not use any renewable energy technology in their business (1056 - 88%). The companies that were surveyed operate in the tourism industry. The presented results concern only part of the research involving the identification of barriers among people who have not yet invested in renewable energy. The research used graphical analysis, factor analysis and econometric modeling. Factor 1 Factor 2 Factor 3 Factor 4 Factor 5 Lack of credible benefits from using renewable energy sources for environmental protection 0,7236 -0,0430 0,0900 0,0321 -0,0276 Fears about introducing new technologies into the company 0,7341 0,0473 0,0245 0,1903 0,0382 Decrease in demand in the enterprise 0,0670 0,7177 0,0319 0,0346 0,0179 Increased investment risk in the economy 0,0874 0,7490 0,1357 0,0638 0,0404 Loss of financial liquidity 0,0255 0,7513 0,0173 0,1017 0,1022 Dynamic changes in legal regulations 0,0378 0,1376 0,7360 0,0160 0,0285 Lack of appropriate legal regulations in the field of renewable energy 0,0200 0,0182 0,7843 0,1135 0,0441 Inappropriate location of the company in relation to renewable energy resources 0,0850 0,0940 -0,0495 0,7169 0,0225 Lack of experience in implementing innovations 0,0476 0,0084 -0,0249 0,7364 0,1734 Lack of own financial resources -0,0582 0,1239 0,0312 0,0256 0,7551 Variance 1,8775 1,8745 1,7198 1,8707 1,5311 % Variance 0,1043 0,1041 0,0955 0,1039 0,0851 (1,36) (0,15) (0,16) (0,16) (0,12) (0,17) The model of fears about renewable energy investments is presented below. Results: The model fits the data by 40%. (R2 =0.40). The research shows that all constructed factors turned out to be statistically significant and were I ncluded in the model. The respondents assigned the greatest importance t o factor 4, which was the first to enter the model - it is responsible for concerns regarding the location of investments and the lack of experience in introducing innovative investments. If the value of factor 4 increases by one point, the synthetic indicator corresponding to concerns increases by 2.24 points. The second most important factor is the factor responsible for concerns about legal regulations and the variability of regulations regarding renewable energy. The third most important factor was factor 1, i.e. the fear of lack of benefits from the investment. It is surprising that t", "label": "poster"}
{"text": "I. Introduction III. Inpainting IV. Results and discussion One of the fundamentals of the standard model of cosmology is the statistical isotropy of the universe at large scales. However, WMAP and Planck temperature data show evidence of several anomalies hinting that the large-scale anisotropies are not fully compatible with the statistical isotropy assumption. In particular, one of them, known as \u201chemispherical power asymmetry\u201d [1], suggests a directional dependency of the anisotropies. This asymmetry has been found using different estimators with a significance close to 3\u03c3 [2, 3, 4]. Modeling the asymmetry in terms of a dipolar modulation [2] allows us to determine the statistical significance, the direction, and the amplitude. In temperature the observed asymmetry is compatible with a modulation of ~7% [2, 4]. Applying the same analysis to the Planck third release (PR3) data, a dipolar modulation was found at modest significance [4] in the E-mode maps. However, anisotropic noise and large scale systematics plays an important role in this analysis. In this work we repeat the analysis using both, PR3 and the new Planck fourth release (PR4) data [7], which provides an improved data set (especially in polarization) with reduced systematics and noise. In addition, we also work with a new alternative inpainting approach, which is necessary to reduce the E/B mixing. The preliminary results show that using a set of 300 simulations the p-value increases up to 3.3%, while we have not found differences in the intensity analysis. II. Dipolar Modulation Analysis REFERENCES [1] Eriksen H.K. et al. 2004, ApJ, 605, 14 [2] Hansen F. K. et al. 2009, ApJ, 704, 1448 [3] Akrami Y. et al. 2014, ApJ, 784, L42 [4] Planck Collaboration VII. 2020, A&A, 641, A7 [5] Tegmark M. & Oliveira-Costa A. 2001, PhRvD, 64, 063001 [6] Marcos-Caballero A. et al. 2019, JCAP, 10, 53 [7] Planck Collaboration LVII. 2020, A&A, A42 Following [3], we study the asymmetry by computing the local- variance maps over disks of a certain size. A dipolar modulation, of the form in the fluctuation map would manifest itself as a dipole structure in the local-variance map, so we can fit it by a \u03c72. The first figure shows how a local-variance map looks like starting from a modulated E-mode map. Using simulations we can calibrate numerically the proportionality between the amplitude of the local-variance dipole and the amplitude of the modulation. We can also predict the ability of the method to detect modulations of a given amplitude (see figure on the left). If we apply a mask, we only consider disks where at least 10% of the pixels are unmasked. HEMISPHERICAL POWER ASYMMETRY IN INTENSITY AND POLARIZATION FOR PLANCK PR4 DATA C. Gimeno-Amo1, R. B. Barreiro1 and E. Mart\u00ednez-Gonz\u00e1lez1 1Instituto de F\u00edsica de Cantabria, CSIC-Universidad de Cantabria, Santander, Spain E-mail : gimenoc@ifca.unican.es Local-Variance map at Nside = 16 Working with masked QU maps produce an E/B mixing. In order to have a better E-mode reconstruction we need to fill masked pixels by using an inpainting technique. For the first time in polarization we have implemented an inpainting technique known as \u201cGaussian constrained realization\u201d [6]. We fill the masked pixels coherently with a cosmological model and taking into account the unmasked pixels. The pixel covariance matrix needed for this has 2 contributions: the CMB signal, and the noise and systematics. CMB can be computed from the angular power spectra [5, 6], while noise must be estimated numerically. We have split the noise simulations and used the first half for estimating the covariance matrix and the second for the analysis. Unfortunately, the number of simulations is not enough for the matrix to reach convergence, and the inpainting is not as good as we predicted using only CMB. We have tried a variety of ways of estimating the matrix, and we have chosen the one that minimizes, for the same fsky, the maximum relative error (see green line in the fi", "label": "poster"}
{"text": "This project has received funding from the European Union's Horizon Europe Framework Programme under grant agreement number 101058554. This work was co-funded by the Swiss State Secretariat for Education, Research and Innovation (SERI) and the UK Research and Innovation (UKRI) under the UK government's Horizon Europe funding guarantee grant number 10042534 & grant number 10055606. 2nd NOVA General Assembly| Smolenice Castle| 2023 Stability/Lifespan Durability Chemical/ Abrasion resistance Surface material compatibility Ease of application Water- or solvent-based Appearance Possible impact on the function of the coated object Leaching Toxicological/environmental concerns More information about the Author? Permanent coatings: model paint formulations for photocatalysts Fraunhofer IFAM, Bremen (D) DOI: 10.5281/zenodo.8332165 Claus Schreiner, Dorothea St\u00fcbing, Malinn Kastens and Thalea Czarnik Strengths \u2022 identification of an efficient photocatalyst in combination with a durable matrix would open up ways for very long lasting effects \u2022 combinations with the upconverter pigments could lead to synergistic booster effects \u2022 pure anatase is a pigment commonly used in cosmetics and pharmaceuticals, so no toxicity is expected concerning the undoped material Weaknesses \u2022 as the particles are based on TiO2, all functionalized coatings are at least hazy and can be white to greyish/beige (in case of doped TiO2) \u2022 the effects observed are lasting, but only moderately active \u2022 quite high concentrations of particles can be necessary which influences the general coating performance \u2022 the coating matrices must be robust, otherwise they are decomposed as well Opportunities \u2022 the applicability is very universal, all common coating matrices can be used \u2022 TiO2 is a friendly pigment referring to viscosity properties; in case of white/grey coatings, the functionalization is \u201cinvisible\u201d \u2022 various photocatalytic materials are commercially available and not excessively high priced \u2022 the incorporation in the coating uses standard dispersion techniques (material behaves like rutile TiO2) \u2022 regulatory aspects (although it seems that TiO2 has already gone through this \u201cprocess\u201d) \u2022 too high amounts of photocatalyst added can reduce key features of a given coating (e.g. substrate adhesion) \u2022 starting from clearcoats, the milkiness of the functional coatings might be undesired by the market/customer Threats & Risks Functional Requirements Non-functional Requirements \u2022 Light (visible to UV-A) as well as moisture is necessary for the photocatalytic process; moisture must be available at least at a molecular level (no macroscopic water!) \u2022 the coating matrices must be robust, otherwise they are decomposed as well over time \u2022 the coating matrix must be suitable for the application purpose 1. Claus Schreiner, Volker Z\u00f6llmer: Fraunhofer-funded \u201eCovid Dekont\u201c project, www.compamed.de (\u201eIm Kampf gegen Viren und Bakterien \u2013 Desinfektion mit Licht\u201c), 04/2022. Features \u2022 photocatalysts are usually based on the titanium dioxide modification anatase; except for the photocatalytic activity, the properties are similar to rutile = \u201ccommon\u201d TiO2 \u2022 in the presence of light (UV to visible) and moisture, radicals are formed which decompose organic matter (like bacteria) \u2022 as the polymer matrix is also organic, robust coatings are mandatory for lasting effects Goals (Product Vision) \u2022 versatile coatings with durable antimicrobial properties by: \u2022 screening of a variety of photocatalysts to figure out their strengths and weaknesses \u2022 examination of different coating matrices with respect to the interactions with the photocatalysts (e.g. regarding resistance or inhibition) \u2022 studies on combinatorial approaches with Evonik\u2019s upconverter pigments Durable coatings with unlimited antimicrobial effect depends on the coating matrix; the particles themselves are stable (inorganic pigments!) again, dependent on the coating matrix; surface abrasion leads to uncovered pigments and thus to incr", "label": "poster"}
{"text": "W0830: an extremely cold, missing-link planetary-mass object at the low-mass end of the IMF Daniella Bardalez Gagliuffi1, Jackie Faherty1, Adam Schneider2, Aaron Meisner3, Dan Caselden4, Guillaume Colin4, Sam Goodman4, Davy Kirkpatrick5, Marc Kuchner6, Jonathan Gagn\u00e97, Sarah Logsdon3, Adam Burgasser8, Katelyn Allers9, John Debes10, John Wisniewski11, Austin Rothermich12, Nikolaj Stevnbak Andersen4,13, Melina Th\u00e9venot4, Jim Walla4 1AMNH 2USNO 3NSF\u2019s NOIRLab 4Backyard Worlds: Planet 9 Collaboration 5Caltech/IPAC 6NASA Goddard 7Universit\u00e9 de Montr\u00e9al 8UCSD 9Bucknell University 10STScI 11University of Oklahoma 12University of Central Florida 13Kolding Hospital, Denmark Read more: Bardalez Gagliuffi et al. 2020 Citizen scientists from Backyard Worlds: Planet 9 discovered WISE J0830+2837, an extremely red source moving at 2\u201d/yr in multi-epoch WISE images. Follow-up NIR HST imaging did not detect the source, even though it was bright in Spitzer images. The red color and non-detection in the NIR indicate that W0830 is extremely cold. With our Spitzer parallax, we can place the object at 11pc with a Tef \u2248350 K. Assuming an age of 1-10 Gyr, W0830 is a planetary mass object of 4-13 MJup. W0830 fills a temperature gap between the coldest known brown dwarf (W0855, 250K[4]) and the rest of the Y dwarf population. Spitzer ch2 W0830 Spitzer ch1 W0830 W0830 W0830 HST F125W HST F125W Data from Bardalez Gagliuffi et al. 2019, Best et al. 2020, Kirkpatrick et al. 2021 Atmospheric models from Morley et al. (priv. comm.) Temperature sequence Metallicity? Surface gravity? 450 K 250 K 350 K W0830 This object is a crucial bridge connecting W0855 to the warmer Y dwarf population. Following the decommissioning of Spitzer, further characterization of W0830 will require either JWST or much deeper images from HST. Establishing metallicity, surface gravity, and temperature from its SED would aid in interpreting the role of fundamental properties in this temperature regime. Modified from Bardalez Gagliuffi et al. 2020 With temperatures \u2264500K, Y dwarfs are some of the lowest-mass products of star formation[1]. Only ~40 Y dwarfs are known (30% of those with BYW![2,3]) and are critical to understanding the complex atmospheres of giant planets like Jupiter and the tail end of the IMF. References [1] Cushing et al. (2011) [2] Bardalez Gagliuffi et al. (2020) [3] Meisner et al. (2020a) [4] Luhman (2014)", "label": "poster"}
{"text": "GROUND REACTION FORCES INDICATE OLDER WOMEN AND CHILDREN HAVE DIFFERENT GAIT STRATEGY Rafael Baptista1, Vandressa Vargas, Leandro de Souza, Leandro Giacomazzi, Gustavo Heidner, R\u00e9gis Mestriner, Andr\u00e9ia Aires, Rodrigo Nascimento e Marcus Vieira2. 1PUCRS e 2UFG. 1. INTRODUCTION The purpose of this study was to compare the GRF during the gait and its derived parameters between children and older women 2. METHODOLOGY Twenty-five children (age 6.39\u00b11.88 years) and thirty- three elderly women (age 70.48\u00b16.66 years) took part in this study. Each participant performed five trials following a verbal cue, at a self-selected pace, while wearing sports footwear, on a 6.0 m long by a 1.4 m wide walkway with 8 embedded force platforms (BTS Bioengineering). 3. RESULTS 4. CONCLUSION Significant differences in kinetic gait parameters were observed when comparing elderly women and children. Based on GRF, stance phase times, and impulses we have concluded that elderly women walked slower than children, with longer stance phase duration, increased step rate, and shorter stride length. These differences are likely the results of the opposite strategies adopted by each group. This study was financed in part by the Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de Nivel Superior \u2013 Brasil (CAPES) \u2013 Finance Code 001. e-mail: rafael.baptista@pucrs.br Table 1. Summary of GRF Vertical Parameters Note. Par. = Parameters; Gr. = Group; M = mean; SD = standard deviation; df = degrees of freedom; d = Cohen\u2019s d. \u2020 = Mann-Whitney significant.", "label": "poster"}
{"text": "Community oral history in the CLARIAH Media Suite Stories in Motion Re-use Collect Archive Collect and curate \u2713Obtain high audio quality to optimize use of open source ASR webservice (CLST Automatic Speech Recognition for Dutch) and/or use time-coded interview summary template. \u2713Create metadata with a DCMI template for object and collection level use. \u2713Use thesauri to enhance discoverability of interviews in repositories and archives. Deposit and re-use \u2713Use a GDPR compliant informed consent form using accessible language and a CC BY-NC-SA 4.0 data license. \u2713Deposit community oral history archive at an appropriate repository, including DANS-EASY, enabling the CLARIAH Media Suite to harvest (meta)data from DANS. \u2713Use an accessible deposit and processing agreement for the community archive collection owner. Results: \u2713A toolkit containing a workflow, glossary and templates supporting grassroots heritage organizations in the Netherlands in making their oral history archives re-usable through standards for data interoperability, empowering them to work more autonomously. \u2713The opportunity for scholars and students to search, bookmark and annotate community oral history in the CLARIAH Media Suite environment. Presented at DH Benelux 2022 RE-MIX - Creation and alteration in DH, 1-3 June University of Luxembourg Norah Karrouche, Vrije Universiteit Amsterdam Marjan Beijering, Erasmus Universiteit Rotterdam Partners: DANS (Femmy Admiraal), DIG IT UP (Simone da Silva), Stadsarchief Rotterdam (Marie-Claire Dangerfield) Visit the Media Suite Objective: Developing a model for making community oral history archives in the Netherlands accessible as sustainable data within the Dutch infrastructure for the Arts and Humanities CLARIAH. Method: In order to create a model we trained and studied volunteers from a community archive project (DIG IT UP) in a series of workshops, in cooperation with Stadsarchief Rotterdam. We examined the project partners\u2019 approaches to oral history and their minimal requirements for re-use as archival and research data. Relevance: Community oral history is a popular method for grassroots organizations to explore histories of communities that have left few textual traces in archival institutions. Once collected, community oral history in the Netherlands is rarely stored and curated because grassroots organizations lack the awareness and/or digital skills to deposit oral histories as data in archives and repositories. Community oral history has the potential to uncover hidden voices and add to multiperspectivity in historical research.", "label": "poster"}
{"text": "Camille Landri, Ond\u0159ej Pejcha, Micha\u0142 Pawlak, Andrzej Udalski, Jose L. Prieto, Manuel Barrientos, Jay Strader and Subo Dong Type of cataclysmic variable (CV), white dwarf accreting matter from a companion via an accretion disc. Accretion disc undergoes semi-periodic outbursts, best explained by the Disc Instability Model (DIM, Smak 1982): \u2022 Disc initially cold and stable. \u2022 Disc temperature and surface density increase as mass builds up. \u2022 Disc reaches critical conditions and local instability propagates: sudden rise in temperature and brightness (outburst). Dwarf nova (DN) outbursts typically last for a few days and recur every few weeks. OGLE-BLG504.12.201843: A POSSIBLE EXTREME DWARF NOVA Camille Landri 1, Ond\u0159ej Pejcha 1 et al., 2022, MNRAS, 517, 2746 OGLE-BLG504.12.201843 02 WHAT IS A DWARF NOVA? 01WHITEDWARFACCRETIONDISCCOMPANION PAPER REFERENCES ABOUT ME CV discovered with OGLE (Udalski 2015) by Mr\u00f3z (2015). Peculiarities: \u2022 300 days long outbursts recurring every 1000 days, \u2022 slow brightening before outburst, \u2022 small recurring flares in quiescence. 05 WHY IS THIS SYSTEM INTERESTING? PHOTOMETRY 03 Figure 1: Photometry of O-201843. Upper panel: Archival data from DASCH (Laycock 2010). Middle panel: Data from OGLE. Left panel: Small recurring flares. Right Panel: close-up of an outburst with dates at which spectra were obtained. We acknowledge the support by INTER- EXCELLENCE grant LTAUSA18093 from the Ministry of Education, Youth, and Sports. The research of OP has also been supported by Horizon 2020 ERC Starting Grant \u2018Cat-In- hAT\u2019 (grant agreement no. 803158). Ellipsoidal modulations during quiescence. In outburst, one minima disappears, the other deepens. The outbursts come from an accretion disc. Companion hides part of the disc Disc brightness hides orbital modulations Figure 2: Phased light curve of O-201843. Left: Quiescence. Right: Outburst. SPECTROSCOPY 04 Figure 3: Evolution of the H\u03b1/HeII lines during an outburst. Balmer absorption lines: \u2022 early F-type companion and/or accretion disc. He II emission lines during outbursts. No common features of DNe: \u2022 Double peaked lines. \u2022 Emission in quiescence becoming absorption in outburst. Spectra consistent with cold accretion discs modelled with the DIM (Idan 2010). Likely a DN with extreme properties: long outburst cycles, relatively young companion. More importantly: \u2022 Small flares in quiescence have not been observed in other DNe. \u2022 Unusually cold disc in quiescence. \u2022 Brightness increase in quiescence is a prediction of the DIM, but is never observed in DNe. 0-201843 is a great system to learn more about thermally unstable accretion discs and requires further studies! 1Institute of Theoretical Physics, Charles University, Prague, Czech Republic 14 Idan et al., 2010, A&A, 519, A117 Laycock et al., 2010, AJ, 140, 1062 Mr\u00f3z et al., 2015, Acta. Astron., 63, 313 Smak J., 1982, Acta. Astron., 32, 199 Udalski et al., Acta Astron., 65,1 ACKNOWLEDGEMENTS", "label": "poster"}
{"text": "RESEARCH INFRASTRUCTURES OF THE FUTURE \u0141UKASZ BOLIKOWSKI, DOMINIKA CZERNIAWSKA, WOJTEK SYLWESTRZAK CENTRE FOR OPEN SCIENCE, ICM, UNIVERSITY OF WARSAW OUR VISION Large, open, distributed research infrastructures will play an increasingly important role in re- search communication. Their future will be driven by the following three factors. 1. Increasing role of (big) data in research. From social sciences to medical biology, researchers will analyze large, open data repositories. 2. Emergence of autonomous research agents. Research process will no longer remain a human- only domain, machines will be increasingly important actors. 3. New communication models, including dynamically changing, heavily interlinked, openly ac- cessible research objects of varying forms. BIG DATA Big data sets contain information with enor- mous commercial and cognitive value. As a con- sequence, big data sets and data-driven research become crucial in almost every discipline of sci- ence, from social sciences to medical biology. Progress in data-driven research is hindered by prevalence of information silos. Research in- frastructures of the future should aim at opening and integrating the said silos by creating solu- tions enabling sharing and merging diverse data sets, as well as providing advanced technologies and tools for scalable data analytics. Additionally, societal externalities of big data in science will stimulate emergence of new types of scientints, new practices of knowledge cre- ation, which in turn will require new standards of communication. AUTONOMOUS AGENTS In order to cope with information overload and large quantities of data, researchers will off- load part of their work to machines. Therefore, research discoveries will no longer be a human- only domain (cf. \u201cRobot Scientist Adam\u201d). Research infrastructure with medium- and long-term perspectives should take into account the increasing role of machines in research activi- ties. In particular, the said infrastructures should provide machine-friendly communication proto- cols and ontologies, capable of expressing hy- potheses, methodologies, and results. In consequence, autonomous research sys- tems will be not only consumers, but also pro- ducers of knowledge. NEW COMMUNICATION Open access research infrastructures of the future will enable new forms and models of re- search communication. Differences in publishing data and text will gradually disappear. Compound research ob- jects will be published, consisting of: text, data, interactive graphs, and audiovisual material (cf. Elsevier\u2019s Article of the future). Content will be published in machine-readable form, levaraging semantic networks (e.g. Linked Open Data). Published objects will have more diverse forms and sizes, from nanopublications to book series and large data sets. Publications will have a dynamic character (e.g. executable papers, liq- uid publications), with comments and follow-up discussion.", "label": "poster"}
{"text": "Cognitive Psychology, 29(1), 1\u00ad23. Infant and Child Development, 13 Advances in Infancy Research, 5, 69\u00ad95. Infancy, 17 Journal of Child Language, 41 Frontiers in Psychology, 4 Background: 1 Research Question Can we identify factors that influence the outcome of a segmentation study? age familiar novel 2,3 language background Database Information Effect Sizes for repeated measures \u201c \u201d ES References Open Science sites.google.com/site/InWordDB Join us! submit data Coordinate extensions ... Results g p 3951 infants \u00be \u00bd 200 250 300 350 400 Age (days) American English Canadian French European French Other Germanic Other Formula g) \u201c \u201d Study ID Participants Stimuli Procedure Results Effect size", "label": "poster"}
{"text": "Open Access Helpdesk: Behind the Scenes Andreas Kirchnera,b , Hannah Schneidera,b & Paul Schultze-Motela,c aBMBF-Projekt open-access.network; bKommunikations-, Informations-, Medienzentrum (KIM), Universit\u00e4t Konstanz; cHelmholtz Open Science Office, Helmholtz-Gemeinschaft open-access.network. Das von 2019 bis 2022 gef\u00f6rderte BMBF-Projekt open-access.network schafft ein neues Informations- und Vernetzungsangebot zum Thema Open Access. Die drei zentralen Ziele des Projektes sind die Bereitstellung von Informationen, die Kompetenzvermittlung sowie die Vernetzung der bestehenden Community. Lizenz: CC BY 4.0 Open-Access-Tage 2021 Online, 27.-29. September 2021 E-Mail Jederzeit: help@open- access.network Telefon Di & Do per Telefon: 14-16 Uhr unter (+49)7531/ 88 33 66 Chat Bisher zwei Tests mit versch. Tools, abschlie\u00dfender Test im Winter 2021/22 \u201eWenn ein Artikel als Erstver\u00f6ffentlichung bereits eine CC BY-Lizenz hat, hat dann der Autor automatisch das Recht, die Verlags-PDF auf einem (institutionellen) Dokumentenserver abzulegen?\u201c \u201eGibt es neben Universit\u00e4ten und nationalen F\u00f6rderern noch Stiftungen oder EU- Organisationen, bei denen ein Zuschuss f\u00fcr eine OA- Ver\u00f6ffentlichung von Monographien m\u00f6glich ist?\u201c \u201eVielen herzlichen Dank f\u00fcr diese schnelle und hilfreiche Antwort! Toll, dass es diesen Helpdesk gibt!\" Zielgruppe: Wissenschaftler*innen und alle, die spezielle Fragen zu Open Access haben Anfragen bisher: \u2022 mit \u00fcberwiegend hohem Komplexit\u00e4tsgrad \u2022 von Wissenschaftler*innen und Open-Access-Professionals \u2022 thematische Schwerpunkte der Anfragen: Finanzierung von Open-Access-B\u00fcchern, Urheberrecht / Lizenzen und Qualit\u00e4tssicherung Qualit\u00e4tssicherung: Abstimmung der Antworten zwischen den Bearbeiter*innen, um eine hohe Qualit\u00e4t zu gew\u00e4hrleisten (bei E-Mail-Anfragen) Nachnutzung: Fragen und Antworten als Wissensbasis und Grundlage f\u00fcr die sp\u00e4tere Erstellung einer FAQ-Liste Expert*innen aus dem Projekt open-access.network antworten auf Fragen rund um das Thema Open Access Antwortzeit 2 Tage", "label": "poster"}
{"text": "IMPLEMENTATION OF TWO CIRCULAR ECONOMY DEMONSTRATION CASES IN PORTUGAL: CHALLENGES AND LEARNINGS Nazar\u00e9 S. Almeida*, Susana Pereira, Pedro Branco, Luis Machado, Paula C. R. Pinto RAIZ \u2013 Forest and Paper Research Institute, Quinta de S. Francisco, Eixo, 3801-501 Portugal *Corresponding author: nazare.almeida@thenavigatorcompany.com; INTRODUCTION METHODS \u2013 PILOT PROJECT ROADMAP RESULTS AND DISCUSSION CONCLUSIONS REFERENCES XXV TECNICELPA - Confer\u00eancia Internacional da Floresta, Pasta e Papel XI CIADICYP 2021, 9, 10, 11, 12 mar\u00e7o 2021 \u2013 WebConference, Portugal This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement No 730305 Most of the current waste streams generated by the Pulp & Paper industry (PPI) are currently used for energy recovery and land reconstruction. However about 15% of the produced waste are still disposed in landfills [1]. The Paperchain project comes up as an innovative demonstrative project that proposes factual applications for different underused PPI waste streams by proving the technical, economic and environmental feasibility on different sectors through implementation of five real scale pilots. [1] CELPA, Boletim Estat\u00edstico, (2019) (http://www.celpa.pt/wp-content/uploads/2020/11/BE_2019_WEB.pdf); The Portuguese circular case covers two types of construction materials: pre-cast concrete which is completely replaced by lime ash (CC1a) and bituminous mixture where the fine aggregate and filler is partial replaced by dregs and grits (CC1b). UNIQUE ENVIRONMENTAL TITLE (TUA) ARTICLE 32 OF DECREE LAW N\u00ba 178/2006) LICENSING PROCESS A B C D After production, the precast concrete was discharged inside of columns and beams mould (A). During the discharge process, were installed thermal sensors (B) for strain and thermal internal monitoring in two beams. Once all the beams and columns were dried, SPRAL proceeded with land preparation as well as the installation of bases for columns fit (C). After the installation of the eight columns and the four beams resulted the final pavilion (D). E F G H I CC1a \u2013 PRECAST CONCRETE CC1b \u2013 ASPHALTIC ROAD The dregs and grits used on CC1b here dried (A) and sieved before the integration on the bituminous mixture. Once achieved the necessary moisture and dimension, the wastes were integrated in bituminous mixture and transported to NVG plant. Before the installation of the bituminous mixtures (reference, integrating dregs and grits) the underlying layer has prepared and cover with tack coat (B). The bituminous mixtures application at NVG facilities were made by Megavia (C). The asphalt preparation and application work was completed in 7 days, in the first week of March 2020 (D). ONE YEAR MONITORING OF ENVIRONMENTAL (LEACHATE) AND TECHNICAL (RESISTANCE) MONITORING \uf0a7Good technical performance \uf0a7No environmental issues (preliminary results) \uf0a7Legal constrains to overcome in favor of demonstrative project (behind paperChain) Raw material Lime Ash (\u2248 3 ton) Pre-cast concrete preparation CC1a European Standard: EN 13225 Lime ash Limestone Pre-treatment (dry and sieve) Raw material Dregs & Grits (\u2248 6 ton each) Transport Bituminous mixture preparation European Standard: AC 14 Surface CC1b Reference Dregs Grits ACKNOWLEDGMENTS More information of the Project: https://www.paperchain.eu/ LIFE-CYCLE ASSESSMENT PUBLIC DISSEMINATION ECONOMICAL ASSESSEMENT", "label": "poster"}
{"text": "Background image credits: NASA GSFC SVS https://svs.gsfc.nasa.gov/vis/a030000/a030900/a030998/1-SMD-FLEET_MASTER_11_23_2020.png Your Mission\u2019s Open Science Journey A \u201cChoose Your Own Adventure\u201d Rebecca Ringuette, Heliophysics Digital Resource Library, NASA Goddard Space Flight Center on behalf of many contributors and supporters Link to corresponding slides. Motivation SPD-41a Moving Forward Contributors and Supporters Participation Instructions Sample Tasks (see slides for more!) Sign-up for Open Science 101 Research shows that incorporating open science practices accelerates our work and brings a diversity of perspectives to the table. While incorporation of open science practices is being encouraged from multiple entities, guidance directly relevant to missions is lacking. We present a range of practical suggestions based on the general characteristics of the PUNCH mission, NASA\u2019s SPD-41a policy, and the input of a growing number of collaborators across science to encourage a welcoming, open, and collaborative atmosphere, including advancing mission science, improving the quality of the mission products, and building public trust. We welcome feedback and collaboration on these suggestions as we work towards a more complete list of possible open science activities for missions in Heliophysics and across science. Abstract DASH Workshop, Oct 9-11, 2023, at JHU/APL", "label": "poster"}
{"text": "Identification of the environmental impact of materials and processes Manufacturing and assembly of modular and reusable Electric Vehicle battery for environment-friendly and lightweight Innovative Electric Vehicles\u2019 batteries for environment-friendly and lighweight mobility The MARBEL project is manufacturing the next generation of lightweight battery packs with the objective to accelerate the mass market take-up of electric and hybrid vehicles. MARBEL focuses on the need for fast-charging and long- lasting batteries to boost end-user demands, while applying high modularity and easy assembly and developing novel testing methodologies. The project aims at designing, developing and demonstrating new modular, compact, lightweight and high-performance battery packs, together with flexible and robust Battery Management Systems, for battery Electric Vehicles and plug-in hybrids, while maintaining safety levels, allowing fast, high-quality and cost-effective large-scale production by following eco-design principles. 2nd life reuse Solutions and processes for parts\u2019 sustainable dismantling and 2nd life. Advanced BMS Flexible advanced Battery Management Systems (BMS). Ultra-fast charging Ultra-fast charging strategies and enhanced thermal management for an extended useful battery life. Design-for-Assembly & Disassembly Advanced battery packs using a Design-for-Assembly and Disassembly methodology. Ligthweighting the battery package Reducing the weight of the metallic parts. www.marbel-project.eu @Marbel_H2020 MARBEL H2020 project info@marbel-project.eu The project has received funding from the European Commission\u2019s Horizon 2020 programme. Grant N\u00ba 963540 3,5 years duration 1st January 2021 30th June 2024 Collaborative project 16 partners from 7 countries Budget 11,7M\u20ac, of which 9,8M\u20ac funded by the European Commission under the Horizon 2020 research and innovation programme. Sustainable dismantling, reuse and second life applications of battery- pack components and materials Use of reciclable lightweight materials Duration 42 months A circular economy approach to EV battery technology MARBEL\u2019s solution uses secondary raw materials and works on developing a more material and energy resource-efficient battery system, ensuring it is easy to dismantle, refurbish, and repurpose for second-life applications. Batteries for shorter charging time and longer journeys The project is developing modular and reusable EV battery technology, which has a longer lifespan of up to 300,000km and a greater energy efficiency in charging and energy use. MARBEL aims to reduce the environmental impact of batteries by 20% throughout their life cycle, ensuring they are easy to dismantle, refurbish, and repurpose for second-life applications. MARBEL aims to foster the acceptance and use of Electric Vehicles by solving two of the main critical points in consumer\u2019s decision-making: limited vehicle autonomy and charging time, enabling to travel longer distances", "label": "poster"}
{"text": "Predicting masking release of lateralized speech Alexandre Chabot-Leclerc, Ewen N. MacDonald, and Torsten Dau Hearing Systems group, Department of Electrical Engineering, Technical University of Denmark, DK-2800 Lyngby, Denmark alech@elektro.dtu.dk Background The binaural mr-sEPSM (Bin-sEPSM) is a binaural exten- sion of the multi-resolution speech-based envelop power spectrum model (mr-sEPM; J\u00f8rgensen et al., 2013). It uses a short-term equalization\u2013cancellation process (EC) to model binaural unmasking. It can account for spatial masking release with different masker types (speech- shaped noise (SSN), speech-modulated SSN, multi-talker babble, and reversed-speech) and a number of maskers, in both anechoic and reverberant virtual environments (Hawley et al., 2004; Beutelmann et al., 2010). It can also account for masking release of lateralized speech with one SSN masker lateralized to the same, or oppo- site side of the target (L\u02ddocsei et al., 2015). The cur- rent study investigated the same lateralized condition, but with multiple reversed-speech maskers where none, some, or all maskers were presented on the same side as the target. The binaural mr-sEPSM Peripheral processing S+N Equalization Peripheral processing Cancellation Modulation \ufb01ltering SNRenv Binaural selector N (\u03b10, \u03c40) S+N N \u2026 \u2026 \u2026 \u2026 Right ear Left ear Binaural path Intelligibility conversion Fig. 1: Structure of the binaural mr-sEPSM. \u2026 Two monaural mr-sEPSM (see Fig. 2 for overview). \u2026 An EC process with channel-independent pa- rameters, computed in 20 ms windows, for the binaural unmasking (BU) pathway (Wan et al., 2014). \u2026 A binaural selector which selects the best of the \u201cbetter-ear\u201d SNRenv (BE; between left and right) and of the BU SNRenv in the multi- resolution representation. \u2026 Conversion to intelligibility using a Gaussian psychometric function. Fig. 2: Structure of the monaural mr-sEPSM (repro- duced from J\u00f8rgensen et al., 2013). Results Fig. 3: Top panel: Measured SRTs (open squares) and predictions by the Bin-sEPSM (blue squares) and the \u2018left-\u2019 and \u2018right-ear\u2019 models (red triangles) for each con- dition. S conditions are with SSN maskers and C con- ditions are with reverse-babble maskers. Lower panel: Replot as masking release relative to the S11 condition. Table 1: Model performances. The bias is the mean difference between predictions and data SRTs, and r2 is the correlation coef\ufb01cient. Model Bias r2 Bin-sEPSM -2.17 0.78 Left and Right 1.22 0.53 Stimuli and conditions Notation: # of co-located maskers # all maskers - example A T M1 M2 T M1 M2 - example B T M1 M2 T M1 M2 Fig. 4: Each stimuli is steered to the left or right, using a 680 \u03bcs lead at one ear (marked by rectangles). The monaural SNR is the same in both examples. Figure from L\u02ddocsei et al. (2015). \u2026 SRTs measured by L\u02ddocsei et al. (2015) using the open-set DAT corpus (Nielsen et al., 2014). \u2026 Maskers: \u2026 SSN matched to target (S\uebf81); \u2026 2/4/8 reversed male talkers from GRID sen- tences (Cooke et al., 2006) (C\uebf82/C\uebf84/C\uebf88). Acknowledgements This research was supported in part by the National Science and Engineering Research Council of Canada (NSERC), Phonak, and the Technical University of Denmark. Discussion \u2026 The left- and right-ear predictions depend only on the total number of maskers, con\ufb01rming the constant SNR and energetic masking (EM) on a given side. \u2026 BU processing is required for predicting a re- lease from masking between all-collocated and all-separated conditions, e.g., between C44 and C04. \u2026 The Bin-sEPSM does not capture the increased SRT in the C22 condition due to increased confu- sions between target and maskers. \u2026 It is assumed that the Bin-sEPSM has perfect segregation between the target and maskers because of its inputs (speech and noise mixture, and noise alone). Therefore, it might require an estimate of the similarity between target and maskers to account for confusions, which is con- sidered a source of informational masking (IM; Watson, 2005). Fig. 5: Euclidean distan", "label": "poster"}
{"text": "Signal denoising in modular spiking networks Barna Zajzon1,2, Abigail Morrison1,3, Renato Duarte1 1 Institute of Neuroscience and Medicine (INM-6) and Institute for Advanced Simulation (IAS-6), J\u00a8ulich Research Centre and JARA, J\u00a8ulich, Germany 2 Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Germany 3 Software Engineering, Department of Computer Science 3, RWTH Aachen University, Germany Contact: b.zajzon@fz-juelich.de 1. Introduction \u2022 Topographic maps, comprising ordered projections among distinct neuronal populations, are a well-studied and pervasive structural feature of the cortical hierarchy, yet little is known about their functional relevance \u2022 We investigate the impact of key structural parameters of topography in the context of a signal reconstruction task in a sequential setup: modularity, map size and degree of overlap \u2022 Information transmission improves as topographic projections become more structured \u2022 This structuring, de\ufb01ned here in terms of modularity, causes a disruption in the E-I balance and leads to the emergence of inhibition-dominated regimes \u2022 In some conditions, networks operating in such regimes exhibit spatial denoising properties and the task performance improves vastly with hierarchical depth 2. Network architecture & task \u03bdX m=0 m=0.8 m=1 neuron id (Ei) neuron id (Ei+1) additive Gaussian noise no noise ... encoder S1 Stimulus sequence S2 S1 S2 S1 S2 times [ms] M0 M2 M1 topographic modularity (feed-forward connections): m = 1 \u2212p0 pc \u2208[0, 1]. p0: inter-cluster connection probability pc: intra-cluster connection probability cluster: corresponding stimulus-speci\ufb01c populations \u2022 Modules are balanced random networks of LIF neurons (6 modules) \u2022 Structured stimuli drive speci\ufb01c neuronal clusters in M0, building a topographic map \u2022 Treat local microcircuits as state-dependent processing reservoirs (Reservoir Computing) [2] \u2022 Task: reconstruction of a continuous signal corrupted by Gaussian (spatial) noise 3.Signal reconstruction from noisy input \u2022 Modularity in the topographic projections is essential for accurate reconstruction of the input signal (see also [1]) \u2022 For m >\u223c0.82 gradual but signi\ufb01cant improvement in the decoding, in all modules \u2022 Spatial segregation is increasingly preserved along the topographic maps with larger m (denois- ing) \u21d2information is encoded and transmitted primarily through the activity of these clusters 4. Modularity controls the E-I balance \u2022 Mean-\ufb01eld analysis: \ufb01ring rates of the active (non-active) clusters increase (decrease) with m \u2022 For larger values of m, the E-I balance is disrupted. Neurons in clusters associated with the active stimulus receive signi\ufb01cantly more net overall excitation, the others become more inhibited \u2022 The spatially encoded signal is ampli\ufb01ed through the network (in inhibition-dominated regimes) \u2022 Dynamical system\u2019s perspective: these e\ufb00ects arise due to a change in the e\ufb00ective connectivity \u2022 As the population activity becomes increasingly entrained by input for larger m, the spectral radius contracts with network depth, suggesting a decrease in the richness of the dynamics \u2022 Modular projections onto the inhibitory populations stabilize the system 5. Constraints on the map size \u2022 Trade-o\ufb00between modularity and map size, lower bound on map size \u2022 Cluster overlap has a clear detrimental e\ufb00ect on the task performance \u2022 Progressively larger clusters mimicking an anatomical feature of cortical maps [3] can lead to substantial performance improvement for moderate topographic precision Discussion \u2022 Structured connectivity, (possibly) in form of modular topographic projections, is required for accurate information transmission and can enhance spatial features of the input \u2022 The denoising phenomena relies on increasingly inhibition-dominated regimes in the hierarchy that emerge through modular projections \u2022 Role of topographic modularity in denoising can be understood as a transient, stimulus-speci\ufb01c change in the e\ufb00ec", "label": "poster"}
{"text": "Introduction WiNGS is a federated platform aimed at privacy-preserving but cross-center collaborations on genomic data. It contains the necessary modules to annotate both variants and samples, control data access and perform in depth data analysis. It is an open-source and collaborative genetic variant interpretation platform to analyze DNA variants in both research and diagnostic settings. WiNGS can be accessed interactively using the web-based user-interface. Additionally, WiNGS offers RESTful API which can be integrated into existing routine pipelines. Federated approach for genomics data sharing and analysis N.Sattanathan1, B.Huremagic2, J.Vermeesch2,Y.Moreau2, G.Vandeweyer1 1. University of Antwerp, Belgium ; 2. Catholic University of Leuven WiNGS Infrastructure Analysis approach WiNGS features a powerful and versatile module for a variety of sample based analyses, including single sample and trio-based. Trio-based filtering can be applied on the precomputed subset of (non-) inherited variants. These can be de novo, maternal, paternal and recessive. Additionally, compound heterozygous variant filtering is also available as WiNGS REST API. Conclusion Access to WiNGS is provided as an online service equipped with multiple protection layers. First, the centrally managed access control list (ACL) regulates access to samples on a user, or center basis. Second, all sensitive data is fetched on demand from federated instances. Finally, all communication within the system and with the user is encrypted and authenticated. WiNGS Central Infrastructure handles access control, data visualisation and all communication with the federated client hubs(Center). Client hubs hosting WiNGS API are deployed on premise as containerized applications and manage all the sensitive data. WiNGS provides the means to apply genome sequencing both in routine diagnostics and research environments. It is a privacy-preserving federated solution which can be used interactively and also automated. REST API Integration Annotation Options Existing WiNGS infrastructure annotates variants with gene information, predicted functional effect, pathogenicity prediction, population frequencies and disease associations available in ClinVar. (Non) Coding Annotations Variant annotations framework will be extended to report and filter based on the below (non) coding annotations. \uf076Regulatory region observed in specific cell types... \uf076Splice AI and MaxEntScan \u2013 Splicing. \uf076Genome Wide Annotation of Variants. Availability www.wings-platform.org Functional filtering strategy can be applied on a single sample , trio-based subset or variant based subset. Variant based analysis approach, variant discovery is the multi-tier processing flow of WiNGS, allowing simultaneous querying of full-access and anonymized data. Querying for gene/region of interest, queries all clients for variants within the request data type. WiNGS Representational State Transfer(REST) API offers support to integrate WiNGS requests into existing pipelines. API Response is structured in JSON format.To get access to this feature, registered WiNGS users can generate API token using the WiNGS interface.", "label": "poster"}
{"text": "Eggsplorer: A workflow to rapidly evaluate insect resistance based on oviposition 1 Micha Gracianna Devi, Dan Jeric Arcega Rustia Main advantages: 1. 2 . 3. Documentedimages of leaves. High throughputscreening . Handles eggsbetweenhoneydew. 4. Website-based (internal). 5. Exporteddata (.xlsx) of egg countand processedimage wit h level of confidence. Things to be optimized: \u2022 Under/overestimationof egg count . \u21b3The more variationin imag es fortraining, thesmarter the program becomes. Thingsto consider: 1. How low canitgo? Magnification, resolution, cost. 2. How efficientin termsof time & human resource? Acknowledgement: Bart van Marrewij k Jochen Hemmi ng Kas Swink els Lize B raat Wendy van\u2019tWestende 1 2 1 Insect Resistance Breeding, Wageningen University and Research, The Netherlands 2 GreenhouseTechnology, WageningenUniversityandResearch, TheNetherlands Federico F. Espinosa Gina Pavloupolo u Harlino Prayud ha Keming Su 1.High quantityof samples forphenotypingpopulation. 2.Manual quantificationusingbinocularrequiresconstant focus adjustment; a lot of time is required. 3.Leafsamples aftercountingare thendiscarded; no documentation. 4.Variationin human eyecapacity; human error. Tomato Potato , Lotte Caarls Arabidopsis Challengesin conductingwhiteflyassays Abstract Up to date, conventional method is still used to quantify insect eggs for evaluating plant resistance. Commonly, this method includes the use of a binocular and manually adjusting the focus over a leaf segment, followed by counting with a ticke r whenever an egg is spotted. This procedure is laborious and require a good eye skill to distinguish the eggs. In susceptib le toma to a nd pota to plant s, whitefli es c an l ay mo re th an a hundr ed eg gs insi de a cl ip ca ge (\u2300 2 cm ). The se eg gs are sometimes packed in an area and ranges from translucent green to brown depending on the age. Moreover, whitefly eggs that are cov ere d in whit efly h oney dew and hi dden a mong trich omes are diffi cul t to det ect. Furtherm ore, t her e is a limitation to electronically document samples using images from a binocular. Eggsplorer is a workflow especially dev eloped to rapidly evaluate whitefly oviposition. This include the use of a digital microscope that can quickly capture high res olution Z-stacked collages of the whole leaf surface, then importing the images to the Eggsplorer program for egg quantific ation. A deep learning model, based on YOLOv5 , was trained to detect the eggs automatically in the images and deployed using an executable graphical user interface. As evaluated using a testing image dataset, the algorithm has an average accura cy of 0.93 with an error of \u00b1 7 eggs per image and average r2 of 0.95, relative to the manual count.Up to date, conventional method is still used to quantify insect eggs for evaluating plant resistance. Commonly, this method includes the use of a binocular and manually adjusting the focus over a leaf segment, followed by counting with a ticker whenever an egg is spotted. This procedure is laborious and require a good eye skill to distinguish the eggs. In susceptible tomato and potato plants, whiteflies can lay more than a hundred eggs inside a clip cage (\u2300 2 cm). These eggs are sometimes packed in an area and ranges from translucent green to brown depending on the age. Moreover, whitefly eggs that are covered in whitefly honey dew and hidden among trichomes are difficult to detect. Furthermore, there is a limitation to electronically document samples using images from a binocular. Eggsplorer is a workflow especially developed to rapidly evaluate whitefly oviposition. This include the use of a digital microscope that can quickly capture high resolution Z-stacked collages of the whole leaf surface, then importing the images to the Eggsplorer program for egg quantification. A deep learning model, based on YOLOv5 , was trained to detect the eggs automatically in the images and deployed using an executable graphical user interface. As e", "label": "poster"}
{"text": "GENGA, a GPU N-body integrator for planet formation and planetary system evolution Simon L. Grimm Center for Space and Habitability, University of Bern The Solar System contains more than 1 Million known asteroids. Some on near Earth orbits. Timing on NVIDIA and AMD GPUs Dynamics of small bodies in the Solar System. Including Yarkovsky effect, Poynting Robertson drag and mean motion resonances. 10 million years after an asteroid collision, fragments collide with the Earth. Planets are formed by collisions of planetesimals. Gas drag leads to an inward drift of the bodies. Mean motion resonances of Jupiter and Saturn increase the eccentricities. The N-body problem includes N2 force calculations per time step. A symplectic integrator is used to conserve energy over many billions of time steps.", "label": "poster"}
{"text": "Wan Shakira Rodzlan Hasani , Shubash Shander Ganapathy , Chong Zhuo Lin , Halizah Mat Ri\ufb01n , Mohammad Nazaruddin Bahari , Muhammad Haikal Ghazali , Noor Aliza Lodz , Muhammad Ha\ufb01zuddin Tau\ufb01k Ramli , Nur Liana Ab Majid , Jane Ling Miaw Yn , Muhammad Fadhli Mohd Yuso\ufb00 , Noor Ani Ahmad , Anita Suleiman , Ahmad Faudzi Yuso\ufb00 , Venugopalan Balan , Sha\u2019ari Ngadiman Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Selangor, Malaysia Selangor State Health Department (JKNS), Ministry of Health Malaysia, Shah Alam, Selangor, Malaysia Disease Control Division, Ministry of Health Malaysia, WP Putrajaya, Malaysia Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Selangor, Malaysia NMRR-20-720-54598 1. Wold Health Organization. WHO announces COVID-19 outbreak a pandemic - WHO Director-General\u2019s opening remarks at the media briefing on COVID-19- 11 March 2020. Geneva2020 [cited 2020 14 April]. Available from: https://www.who.int/dg/speeches/detail/who-director-gener- al-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020. 2. Ministry of Health Malaysia. Official Portal Ministry of Health Malaysia, Latest COVID-19 Statistic in Malaysia by MOH as at 5:00pm, April 14th: Ministry of Health Malaysia; 2020 [cited 2020 14 April]. Available from: http://ww- w.moh.gov.my/index.php/pages/view/2019-ncov-wuhan. 3. Li B, Yang J, Zhao F, Zhi L, Wang X, Liu L, et al. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. Clinical Research in Cardiology. 2020:1-8. 4. Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive care medicine. 2020:1-3. 5. Guan W-j, Ni Z-y, Hu Y, Liang W-h, Ou C-q, He J-x, et al. Clinical characteristics of coronavirus disease 2019 in China. New England Journal of Medicine. 2020. 6. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavi- rus in Wuhan, China. The Lancet. 2020;395(10223):497-506. 7. Novel CPERE. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China. Zhonghua liu xing bing xue za zhi= Zhonghua liuxingbingxue zazhi. 2020;41(2):145. 8. COVID-19 Surveillance Group. Characteristics of COVID-19 patients dying in Italy: report based on available data on March 20th, 2020. Rome, Italy: Instituto Superiore Di Sanita; 2020. 2020. 9. Yang J, Zheng Y, Gou X, Pu K, Chen Z, Guo Q, et al. Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis. International Journal of Infectious Diseases. 2020. References related to Invasive Ventilatory Support among COVID-19 cases in Selangor, Malaysia P-16 Coronavirus disease 2019 (COVID-19) is an infectious disease caused by a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). On March 11, 2020, the World Health Organization declared COVID-19 a pandemic1. Malaysia has also not been spared from the pandemic with a total of 4,987 infected people and 82 deaths up to April 14, 2020 2. A number of studies have shown that underlying comorbidities are predictors of severe disease outcome and greatly a\ufb00ect the prognosis of the COVID-19 patients3-4. COVID-19 causes severe acute respiratory syndrome and is often associated with intensive care unit (ICU) admission and subsequent mortality. Identifying the risk factors that predicts severity and outcome of COVID-19 patients early in the presentation would be extremely helpful for clinicians in managing the patients \u2022 This is a retrospective study using data collected during COVID-19 outbreak in Selangor, Malaysia. \u2022 COVID-19 con\ufb01rmed cases in Selangor that were noti\ufb01ed up to 13th April 2020 were included into this study. \u2022 A positive case of COVID-19 is con\ufb01rmed based on positive Reverse Transcriptase-Polymerase Chain React", "label": "poster"}
{"text": "Innovative Research for a Sustainable Future www.epa.gov/research Tom Knudsen | knudsen.thomas@epa.gov l 919-541-9776 Computational Modeling of Limb-Bud Dysmorphogenesis: Predicting Cellular Dynamics and Key Events in Developmental Toxicity with a Multicellular Systems Model BK Ahir1, ES Hunter2, NC Baker3, RM Spencer3, RS Dewoskin4, TB Knudsen1 U.S. Environmental Protection Agency, Office of Research and Development 1National Center for Computational Toxicology, 2National Health and Environmental Effects Research Laboratory, 3Lockheed Martin, 4National Center for Environmental Assessment 4. TOXICODYNAMICS: predicting key events 5. PRACTICAL APPLICATIONS OF A MULTICELLULAR SIMULATION o Predictive Toxicology :- new way to integrate masses of HTS data into knowledge of a system o Parameter Sweeps :- high-throughput hypothesis testing to inform experimental design o Mechanistic Models :- track lesion propagation through higher levels of biological organization o Temporal Analysis :- pinpoint key events and mine for quantitative relationships o Dose Predictivity :- compare diverse exposure scenarios across dose, time, duration & mixtures DISCLAIMER: does not reflect EPA policy GENETIC PERTURBATION: hindlimb-bud shown at MCS intervals 10k, 20k, 30k & 40k with SHH field for normal and \u2018virtual knockouts\u2019 disabled for Shh or Gli3 genes (wild-type contour traced magenta). Apical Ectodermal Ridge (AER) and Zone of Polarizing Activity (ZPA) are major signaling centers; pivotal signaling pathways fibroblast growth factor (FGF), sonic hedgehog (SHH), bone morphogenetic protein (BMP) and retinoic acid (RA) were modeled in CellDesigner (www.celldesigner.org/). 1. COMPUTATIONAL EMBRYOLOGY & PREDICTIVE TOXICOLOGY HYPOTHESIS: a computer model that simulates cellular function in a growing embryo can be used to predict the potential impact of chemical exposure during early limb development. 2. SIGNALING NETWORK: spatial information processing Query of Mouse Genome Informatics database (www.informatics.jax.org/) by \u2018abnormal limb bud morphology\u2019 (MP:0005650) returned genes for 132 relevant genotypes. An e-Library developed from these genes (31,701 PubMed records annotated by MeSH terms for limb development) returned 81 genes regulating early limb morphogenesis. CONTROL NETWORK CELL AGENT-BASED MODEL (ABM): multicellular and signaling dynamics were modeled in CompuCell3D (www.compucell3d.org/); the small working prototype simulated mouse hindlimb-bud development between Theiler stages 16-19 (~42h) in ~42,000 Monte Carlo Steps (MCS). 3. CELLULAR DYNAMICS: translation of spatial information o Disabling Shh in the model simulates undergrowth of limb-bud o SHH: posterior regulation of digit number & identity o Disabling Gli3 in the model leads to precocious overgrowth o GLI3R: blocked by SHH but negatively regulates Shh-expression o Future Goal: Model the emergence of digital rays Wild-type Shh-null Gli3-null Rate of elongation (n=5) Shh cell lineage (n=5) Wild-type Shh-null Gli3-null Predicted outcomes digital patterns inferred from the literature; not yet implemented in the model exposure Adhesion Apoptosis Differentiation Migration Mitosis Shape Size AER ZPA Cellular behaviors Signals Simulated outgrowth Shh cell lineage (n=10) control excess apoptosis mitotic arrest mixed effect exposed at MCS 32-38k Excessive apoptosis (n=10) CONTROL APOPTOSIS MITOTIC MIXED scan QR codes to run simulation on mobile device CHEMICAL DISRUPTION: How might local effects predicted by in vitro high-throughput screening (HTS) data such as ToxCast\u2122propagate through the pivotal SHH cell lineage in silico to predict, therefore, a key event in vivo? EXAMPLE: 5-Fluorouracil, a teratogen that disrupts digit formation, perturbed 13 of 650 ToxCast HTS assays at \u226415 \u00b5M: impaired differentiation and increased cell loss (excessive apoptosis); p53- induction, mitotic arrest and cell death. These effects can be fed into the model for translation into predicted outcomes. o Model reac", "label": "poster"}
{"text": "Effects of C-peptide on Adipocytes and Mesenchymal Stem Cells in Human Adipose Tissue Ahmad Ghorbani1, Mohammad Taghi Rajabi-Mashhadi2, Seyyed Abbas Zojaji1, Reza Shafiee-Nick1 1Department of Pharmacology & Pharmacological Research Center of Medicinal Plants, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 2Endoscopic & Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran ABSTRACT Recent studies suggest that proinsulin connecting peptide (C-peptide) may show physiological functions in various tissues. This study was aimed to determine whether C-peptide could be involved in the regulation of lipolysis, adiponectin release, and function of mesenchymal stem cells (MSCs) in adipose tissue. Human subcutaneous adipose tissue was cultured in the presence of C-peptide and lipolysis was determined by glycerol measurement in the conditioned media. Effect of C-peptide on adiponectin secretion was evaluated in differentiated adipocytes. The adipogenic and osteogenic abilities of adipose MSCs were evaluated using Oil Red and Alizarin Red staining, respectively. C-peptide induced a significant decrease in basal lipolysis, a slight decrease (statistically insignificant) in isoproterenol-stimulated lipolysis, and a slight increase in adiponectin secretion at concentration of 8 nM, 16 nM and 4 nM, respectively. It had no effect on adipogenic and osteogenic differentiation of MSCs. However, at concentration of 4 nM, C-peptide significantly increased the proliferative capability of MSCs (p<0.05). These results suggest that C-peptide has physiological effects in human subcutaneous adipose tissue and contributes to the regulation of basal lipolysis and pool of MSCs. INTRODUCTION Recent data suggest that proinsulin C-peptide may exhibit characteristics of a peptide hormone and show physiological functions in various tissues. Diabetic patients show a spectrum of abnormalities in lipid metabolism including uncontrolled lipolysis, and dysregulation of adipogenesis and lipogenesis in adipose tissue. These abnormalities are associated with development of atherosclerosis and cardiovascular diseases. Also, there are some reports that diabetes may impair mobilization ability and wound healing capability of mesenchymal stem cells (MSCs) in the patients with type 1 and type 2 diabetes. Until now, the effects of C-peptide on adipose tissue are not yet well known. The aim of this study was to examine whether CP could be involved in the regulation of lipolysis, adiponectin secretion, and proliferation and differentiation abilities of MSCs in human adipose tissue. MATERIALS AND METHODS Subcutaneous adipose tissue samples were obtained from patients undergoing conventional intra- abdominal surgery. Effect of C-peptide on lipolysis was evaluated in ex-vivo organ culture condition and the level of lipolysis was determined by measurement of glycerol. In separate experiments, MSCs were isolated from adipose tissue samples using collagenase-based technique. Effect of C-peptide on proliferation of MSCs was evaluated using MTT assay. The adipogenic and osteogenic differentiation abilities of adipose MSCs were evaluated using Oil Red and Alizarin Red staining, respectively. Effect of C-peptide on adiponectin secretion was evaluated in differentiated adipocytes. RESULTS C-peptide significantly reduced the level of basal lipolysis (p < 0.05) and showed a slight inhibitory effect (statistically insignificant) on isoproterenol-stimulated lipolysis (Fig. 1). Flow cytometric analysis showed that the MSCs were positive for stem cell-associated markers (CD44 and CD105) and negative for haematopoietic markers (CD34 and CD45). C-peptide at concentrations of 1-16 nM increased proliferation of MSCs (Fig. 2). The effect of C-peptide at 4 nM was statistically significant. Figure 3 shows that C-peptide at concentrations of 4-16 nM had no effect on the level of osteogenic differentiation. Figure 4 demonstrates that ", "label": "poster"}
{"text": "1. Periodic representation 2. Modular organization with different periods: \u2013 relatively narrow range of periods \u2013 no grid with very low or high spatial frequencies; e.g. 0.3 ~ 1.3 m [Hafting 2005, Stensola 2012] 3. Uniform phase coverage within a module. An Optimization Principle for the Emergence of Grid Cell Codes Tzuhsuan Ma1 and Ila Fiete1 1Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts Definition of grid cells Inferred properties of grid representation Background / past work on emergence of grid cells Results Advantage of using constant frequency ratio? Exploring contribution of the loss terms Conclusions 1. We find a minimal set of sufficient conditions for the emergence of grid cell codes. 2. These conditions demand a high-capacity, robust, and translationally-invariant code, and we find that grid cell code is the only solution satisfying them simultaneously. 3. We find no structure in period ratio in these conditions. The observed constant period ratio must come from the other constraints. 1. Remarkable advantages in coding: \u2013 exponential-capacity code [Fiete 2008] \u2013 robust, error-correcting code [Sreenivasan 2011] \u2013 accurate path-integration code [Burak 2009] \u2013 parallel operations [Fiete 2008], and many others. 1. Unsupervised, single module \u2013 Hebbian learning of recurrent weights with place-cell inputs \u2192 grid cells [Widloski 2014] \u2013 Hebbian learning of feedforward weights with place-cell inputs \u2192 grid cells [Dordek 2016] 2. Supervised \u2013 Learning of RNNs with a spatial integration task \u2192 periodic responses, no modules [Cueva 2018] \u2013 Learning of RNNs with a spatial integration task and a 50%-drop out layer \u2192 periodic responses with modules [Banino 2018] Cons: 1) Results largely depend on many constraints and fine-tuning of many hyperparameters. 2) No single explicit objective \u2192 architecture, dynamics, input/output encoding, and various other constraints all influence the solution that emegences. References 1. Banino, A. et al. Vector-based navigation using grid-like representations in artificial agents. Nature 26, (2018). 2. Burak, Y. & Fiete, I. R. Accurate path integration in continuous attractor network models of grid cells. PLoS Comput. Biol. 5, (2009). 3. Cueva, C. J. & Wei, X.-X. Emergence of grid-like representations by training recurrent neural networks to perform spatial localization. ICLR 2018 1\u201319 (2018). 4. Dordek, Y., Soudry, D., Meir, R. & Derdikman, D. Extracting grid cell characteristics from place cell inputs using non-negative principal compo- nent analysis. Elife 5, 1\u201336 (2016). 5. Fiete, I. R., Burak, Y. & Brookings, T. What Grid Cells Convey about Rat Location. J. Neurosci. 28, 6858\u20136871 (2008). 6. Hafting, T., Fyhn, M., Molden, S., Moser, M. B. & Moser, E. I. Microstructure of a spatial map in the entorhinal cortex. Nature 436, 801\u2013806 (2005). 7. Sreenivasan, S. & Fiete, I. R. Grid cells generate an analog error-correcting code for singularly precise neural computation. Nat. Neurosci. 14, 1330\u20131337 (2011). 8. Stensola, H. et al. The entorhinal grid map is discretized. Nature 492, 72\u201378 (2012). 9. Widloski, J. & Fiete, I. R. A Model of Grid Cell Development through Spatial Exploration and Spike Time-Dependent Plasticity. Neuron 83, 481\u2013495 (2014). 10. Wei, X. X., Prentice, J. & Balasubramanian, V. A principle of economy predicts the functional architecture of grid cells. Elife 4, 1\u201329 (2015). What do we want to optimize? The loss functions Loss 1 maximizes coding separability. \u2192 high capacity robust code. Loss 2 minimizes variance along the diagonals of distance matrix. \u2192 translationally invariant (TI) code. Loss 3 minimizes sparsity of the representation. \u2192 representation with narrow range of firing rate. Our appoach 1. We define an optimization problem purely from coding perspective. 2. Our setup is transparent without implicit dynamical constraints of RNNs position (m) cell i initial tuning curves initial spectrum final unsorted tuning", "label": "poster"}
{"text": "Figure 3.4: Body size governs relative time invested in temperature regulation Ratios of the time it takes to cool down versus the time it takes to warm up in crocodiles in air and in water (Smith 1976) compared to a stacked histogram of terrestrial and aquatic body masses. Larger sizes require less warming time with respect to cooling time. Living in air is thermally advantageous at smaller size whereas living in water is preferable at larger size. 3. Results 1. Introduction Twenty-four species of crocodile populate the globe today, but this richness represents a minute fraction of the diversity and disparity of Crocodyliformes since their origin early in the Triassic. Across this clade, three major diversification events into the aquatic realm have occurred. Aquatic and terrestrial habitats impose differing selective pressures on body size. However, previous research on this topic in Crocodyliformes remains qualitative in nature. In this study, our goal was to quantify the influence of habitat (terrestrial versus aquatic) on the evolution of body size in Crocodyliformes. We find a history of repeated body size increase and convergence following shifts to an aquatic lifestyle, suggesting common selective pressures on life in water spanning multiple independent aquatic clades. Convergent body size evolution of Crocodyliformes upon entering the aquatic realm 2. Materials and Methods William Gearty* and Jonathan L. Payne Department of Geological Sciences, Stanford University *wgearty@stanford.edu 4. Conclusions \u2022 All three aquatic clades converge on greater optima, with shorter phylogenetic half-lives and smaller stationary variances \u2022 Lung volume, which has long been proposed as the main constraint on diving capacity, is only a constraint at sizes greater than 10 kg \u2022 The rate of cooling strongly constrains diving capacity at sizes smaller than 10 kg and may be the primary driver of larger body sizes in diving crocodyliformes General Equation of an OU Model: \ud835\udc85\ud835\udc7f\ud835\udc95= \ud835\udf36\ud835\udf3d\u2212\ud835\udc7f(\ud835\udc61) \ud835\udc85\ud835\udc95+ \ud835\udf48\ud835\udc85\ud835\udc69(\ud835\udc95) \ud835\udc4b\ud835\udc61: initial body size \ud835\udec2: strength of selection \ud835\udc51\ud835\udc4b\ud835\udc61: change in body size \ud835\uded4: intensity of random drift \ud835\udc51\ud835\udc35(\ud835\udc61): random variation \ud835\udec9: body size optimum Figure 2.1: Maximum clade credibility tree of Crocodyliformes showing invasions of the aquatic realm within three clades Summary tree of posterior distribution of trees from MrBayes characterless tip-dating analysis of the Crocodyliformes supertree. Tips without habitat and/or size data were dropped. Tip labels indicate terrestrial and aquatic species. Figure 3.1: Aquatic clades converge on larger body size optima Weighted means and 2\u03c3 confidence intervals of model-averaged body mass optima (\u03b8) as estimated by OUwie analyses for terrestrial and aquatic regimes. Aquatic clades have statistically greater body mass optima than the terrestrial regime (p < .001, Mann-Whitney test). \u2022 Calculated body masses of 249 crocodyliformes (living and extinct) using measurements from primary literature \u2022 Assigned habitats based on compilations and primary literature \u2022 Crocodyliformes supertree (Bronzati et al. 2015) \u2022 Species fossil ranges from compilations and PBDB \u2022 Characterless tip-dating analysis using R and MrBayes \u2022 Macroevolutionary Ornstein-Uhlenbeck (OU) model fitting \u2022 OUwie R package (Beaulieu et al. 2012) \u2022 Results model-averaged across 17 different models using AIC Figure 3.2: Aquatic clades converge on shorter phylogenetic half-lives Boxplots of model-averaged phylogenetic half-lives (ln(2)/\u03b1) as estimated by OUwie analyses for terrestrial and aquatic regimes. Outliers have been removed. Aquatic clades have statistically shorter phylogenetic half- lives compared to the terrestrial regime (p < .001, Mann-Whitney test). Figure 3.3: Aquatic clades converge on smaller stationary variances Boxplots of model-averaged stationary variances (\u03c32/(2*\u03b1))as estimated by OUwie analyses for terrestrial and aquatic regimes. Outliers have been removed. Aquatic clades have statistically smaller stationary variances compared t", "label": "poster"}
{"text": "Principal soil series Blount series -On till planes of Wisconsin age, formed in silty clay loam or clay loam till -Fine, illitic, mesic Aeric Epiaqualfs Pewamo series -On moraines, near-shore zones,and lake planes, formed in till -Fine, mixed, active, mesic Typic Epiaqualfs Obtain and prepare yield monitor data. Original estimates from yield monitor -2 0 2 4 6 8 10 % IncMSE Relationships between crop yield and landscape features Ashley Kissick, James Camberato, and Robert Nielsen Purdue University, West Lafayette, IN, USA U N I V E R S I T Y R Introduction Sound agronomic recommendations are crucial for today\u2019s agronomists as they strive for improved yields, profits, and sustainability. Determining the spatial relationships between yield and landscape variation including soil properties, soil texture, and terrain attributes may improve management decisions, particularly with regards to proper nitrogen applicaiton for minimizing both costs to farmers and environmental impacts. Here, we investigate relationships between landscape features and corn yield as part of a preliminary study to model corn yield with variations in landscape attributes, soil properties, and weather. Use cluster analysis to select unique terrain attributes. Select most important variables for model using Random Forest. Variable importance 1. Topographic position index 5. Vertical distance to channel network 4. Valley depth 6. Convergence index 7. Flow accumulation 8. SAGA topographic wetness index 9. Catchment area 10. Topographic wetness index 11. Longitudinal curvature 12. Slope 13. Catchment slope 14. Cross-sectional curvature 15. Diurnal anisotropic heating 3. Modified catchment area 2. Relative slope position -2 0 2 4 6 8 10 %IncMSE 0 10 20 30 40 50 Height 6. Convergence Index 2. Relative Slope Position 1. Topographic Position Index 5. Vertical Distance to Channel Network 3. Modified Catchment Area 4. Valley Depth 8. SAGA Topographic Wetness Index 9. Catchment area 7. Flow Accumulation Field site Questions? Ashley L. Kissick, Ph.D. akissick@purdue.edu 5m raster of yield Calculate terrain attributes from digital elevation model. Catchment area Catchment slope Convergence index Cross-sectional curvature Diurnal anisotropic heating Flow accumulation Longitudinal curvature Modified catchment area Relative slope position Slope Topographic position index Topographic wetness index SAGA topographic wetness index Valley depth Vertical distance to channel network 657200 657300 657400 4456850 4456950 4457050 293.0 293.5 294.0 294.5 295.0 295.5 296.0 Elevation, m 293.0 293.5 294.0 294.5 295.0 295.5 296.0 Lag distance (m) Yield residuals 0.8 1.0 0.4 0.6 0.0 0.2 0 100 150 200 50 250 Semivariance range SAGA GIS Use variogram range as distance for spatial weight matrix Run two models for spatial processes: Predicted Yield 1. Spatial lag model: \u03a5 = \u03c1W\u03a5 + X\u03b2 + \u03b5 2. Spatial error model: \u03a5 = X\u03b2 + \u03b7, \u03b7 = \u03bbW\u03b7 + \u03b5 Lowest AIC (Akaike Information Criterion) Predictors W Results Discussion The most important terrain attributes for predicting corn yield were relative slope position, topographic wetness index, topographic position index, and catchment slope. These results demonstrate that models for predicting corn yield in Indiana need to include landscape features for increased model performance. Since this preliminary study, we have added soil texture and soil properties to the models at the Davis Purdue Agricultural Center. This has substantially improved all models. This analysis met one objective of a larger investigation that will incorporate soil properties, soil texture, and weather patterns into models of corn yield across Indiana landscapes. The focus of future work will investigate relationships between yield and terrain attributes, soil properties, and weather patterns aross Indiana, USA. Standardized coefficient Estimate p-value Topographic position index -0.49 5.51e-05 Catchment slope -0.19 0.03 Silt 0.70 2.20e-16 Topographic wetness index 0.30 9.00e-04 Longitudin", "label": "poster"}
{"text": "Language as a Reflection of Mental Time Travel Leon Derczynski, Department of Computer Science, University of Sheffield Basic tenses need mental time travel Languages communicates temporality in verbs in two ways: tense and aspect. There are formal models for these, e.g. Reichenbach. This breaks verbs into three times: E \u2013 event time \u2013 when it happened R \u2013 reference time \u2013 the viewpoint S \u2013 speech time \u2013 when it was uttered Ref. time invokes an abstract viewing point Determining R tells you where observer is Temporal expressions relate distance Expressions of time may give a granularity \u201cIt will happen in two weeks\u201d \u201cAnd two minutes later, it landed\u201d However, while we might use \u201cone year\u201d, we will rarely say \u201cthree hundred and sixty five days\u201d Granularity gives not only precision - it also the distance from \u201cnow\u201d Larger units \u2192 longer conceptual distance The grounding time is reference time, R, which tends to centre narratives. \u201cON an exceptionally hot evening early in July a young man came out of the garret in which he lodged in S. Place ...\u201d Tense with specific distance Each system of describing time evokes temporal contexts Their semantic vary depending on listener, word choice, and world model I will be there soon I will be there soon I will be there soon Some language systems attach specific distances to tenses Bamileke-Dschang: 1. She [has just] bargained 2. She bargained [earlier today] 3. She bargained [yesterday] 4. She bargained [before yesterday; some days ago] 5. She bargained [a long time ago, e.g. a year or more] \u201cI had eaten\u201d \u201cI will have eaten\u201d \u201cI ate\u201d E S,R E E S E R S R Target near to current time: small, precise unit Target far from current time: large unit, unfocused Funded by the EC\u2019s FP7 under grant 611223", "label": "poster"}
{"text": "COUNTRY Finland KEY WORDS Remote sensing, drones, decision support systems, precision agriculture DISCLAIMER This Practice Abstract reflects only the author\u2019s view and the Branches project is not responsible for any use that may be made of the information it contains. 46 Drones detect local variations and provide tools for agriculture Drone technologies provide tools for improving processes in agriculture and horticulture. Drones are utilized to gain knowledge for precision farming actions, document interesting phenomenon and to get general information from the fields. Drones can contribute the farming firstly by providing relative information about variation within the studied area like the yield amount, secondly by providing absolute information about the studied phenomenon like infestation status and thirdly by accomplishing small works like reseeding. The first two examples are based on imaging and the third applies specific tools developed for the drone. The drone imaging is based on passive remote sensing. The imaging data is processed to georeferenced orthomosaic of the studied area and then classified to relative classes that can be converted to absolute values by additional information. Results are like a yield map, a specific nutrient status map, soil moisture map, vegetation density or crop loss map, a weed area map or a relative infestation map. Spatial analysis methodologies or machine learning technologies are used for the classification. Additional methodologies are needed to put the classification information into actions. By the decision support systems by the detected nitrogen level variation is adjusted to the additional nitrogen fertilizer application plan. The drones that accomplish works are fully integrated systems with maximum payload being tens of kilograms. Drones do not harm the cultivated vegetation, so they can work on demand. The drones are doing pollination, fertilizer application, spraying, seeding, biological plant protection. The aviation rules regulate these operations. Drones will not replace heavy machinery and new approaches are under development. The potential of reducing chemical usage and reducing nutrient leach with working drones is huge since their capability of working repeatedly on demand without disrupting the primary vegetation. DOWNLOAD www.branchesproject.eu AUTHORS Jere Kaivosoja Oiva Niemel\u00e4inen", "label": "poster"}
{"text": "Modulation of early visual processing alleviates capacity limits in solving multiple tasks Sushrut Thorat1, Giacomo Aldegheri1, Marcel A. J. Van Gerven, Marius V. Peelen 1 Equal contribution Donders Institute, Radboud University, Nijmegen, The Netherlands Correspondence: s.thorat & g.aldegheri @donders.ru.nl E X P E R I M E N T A L M A N I P U L A T I O N R E S U LT S C O N C L U S I O N S R E F E R E N C E S N E T W O R K D E S C R I P T I O N P R O B L E M D E S C R I P T I O N Cheung, B., Terekhov, A., Chen, Y., Agrawal, P., & Olshausen, B. (2019). Superposition of many models into one. arXiv preprint arXiv:1902.05522. Gilbert, C. D., & Li, W. (2013). Top-down influences on visual processing. Nature Reviews Neuroscience, 14 (5), 350\u2013363. Thorat, S., van Gerven, M., & Peelen, M. (2018). The functional role of cue-driven feature-based feedback in object recognition. In Conference on Cognitive Computational Neuroscience, CCN 2018 (pp. 1\u20134) Identity? Emotion? modulation Object detection as multiple one vs. all classification tasks (is this object present/absent?) \u2022 Objects: MNIST digits and their permutations When could early modulation be beneficial, in addition to late modulation, in a neural network? (i.e. overcome its wiring cost) When there are capacity limits, caused by e.g.: Small number of neurons in the network Large number of tasks the network has to perform How does the detection performance boost provided by the addition of early modulation vary with the number of tasks and units in the network? Main contrast: modulating early & late neural processing (L1 \u2192 L2 & L2 \u2192 L3) vs. modulating late only (L2 \u2192 L3) \u2022 Measure of interest: detection performance \u2022 Manipulation: number of tasks (100, 250, 500), and number of units in the hidden layer (32, 64, 128) The performance boost provided by additionally modulating early processing is \u2022 directly proportional to the number of tasks \u2022 inversely proportional to number of units in hidden layer M E T H O D S In a multi-task scenario, extracting features common to all tasks might not always be possible. Modulating early visual processing can allow early selection of task-relevant information (Gilbert & Li, 2013) 784 N CUE L1 L2 L3 x3 = [W3(g2 \u2218x2)+ b3]+ L1 \u2192 L2 L2 \u2192 L3 Decision (Present / Absent) \u2022 MLP with one hidden layer \u2022 Variable number of units (N) in the hidden layer \u2022 One-hot cue indicates the task (which digit to detect) \u2022 Cue modulates transformations via bias and gain \u2022 Main network and modulation are trained jointly \u2022 Cue either modulates only the late or both early & late transformations Modulation of early neural processing increases multi-tasking performance in conditions of limited network capacity. Are the advantages of early modulation dependent on a neural network\u2019s capacity limits? Capacity limits can be a result of there being limited number of neurons in the network and/or too many (difficult) tasks. Is this the role of early sensory modulation in biological brains? Forgoing wiring costs in favour of optimality? Further work should look at more natural datasets and tasks: Permuted-MNIST limits the sharing of early visual features In a naturalistic dataset (CIFAR, ImageNet) the effect of early modulation might be different because low-level features are shared across categories Bias modulation does not aid performance on top of gain modulation. e.g. Network (32 units, 25 tasks, early+late) trained with: \u2022 gain only modulation: 94.8% \u2022 bias only modulation: 90.9% \u2022 bias & gain modulation: 94.7% I N T R O D U C T I O N Increasing task difficulty (adding noise to digits) also increases performance boost. Modulation Permutation 1 Permutation 2", "label": "poster"}
{"text": "Listing of patient-matched 3D-printed radiotherapy bolus on the Australian Register of Therapeutic Goods Scott Crowe1,2,3,4, Becca Murray2, Tania Poroa1, Jenna Luscombe1, Debra Vincent1, Alex Livingstone1, Rachael Wilks1,2,3, Tanya Kairn1,2,3,4 1 Royal Brisbane & Women\u2019s Hospital; 2 Herston Biofabrication Institute; 3 University of Queensland; 4 Queensland University of Technology Introduction 3D-printed radiotherapy bolus meets the Australian Therapeutic Goods Administration (TGA) definition of a patient- matched medical device and is therefore subject to regulatory provisions. Specifically, a manufacturer must have the device listed on the Australian Register of Therapeutic Goods (ARTG) as a class I non-measuring, non-sterile device before it can be supplied (i.e. used clinically). This requires a statement or demonstration of compliance with Essential Principles, which define the requirements for safety and performance, the satisfaction of which is summarised for bolus devices. Hazard and risk assessment A risk assessment was performed by a medical physicist, and peer reviewed by an engineer, radiation therapist and physics director. Potential hazard categories were taken from the essential principles checklist, and where potential failure modes existed, controls to minimise risk were conceived and implemented (e.g. quality control tests, instructions for use, technical file documentation). Design and manufacturing plan The technical file for the type of device included a design and a manufacturing plan, informed by ISO 13485.These: \u2022 described the device and how it differed from other solutions (e.g. sheet bolus, wax); \u2022 identified the stakeholders in design and production; \u2022 listed the design and manufacturing requirements (e.g. radiological, geometric, material properties); \u2022 described the design and manufacturing processes (e.g. segmentation, printing, post-processing); \u2022 established the responsibilities of staff members; \u2022 described how the design or manufactured device was verified or validated as meeting the requirements (e.g. quality control tests); \u2022 summarised the instructions for use (e.g. assessment of fit, handling, cleaning, disposal of device). Conclusion The supply of in-house manufactured radiotherapy bolus was facilitated with the ARTG listing. The document templates and processes developed for bolus (and other Herston Biofabrication Institute devices) have subsequently been used for the ARTG listing of radiotherapy immobilisation and positioning devices manufactured and supplied at point-of-care. Case specific documentation For each patient case, the documentation requirements were specified in the technical file for the type of device. The request, design approval (within contour system), fabrication and quality control was captured within our oncology information system, MOSAIQ. This approach allowed responsibilities to be assigned to specific staff or staff groups, and allowed the planning therapist ultimately responsible for the device to monitor progress. Patient specific quality assurance require the acquisition of a CT image of the device, which was used for an assessment of relative electron density (by Hounsfield Unit conversion) and geometric agreement with approved model (by Hausdorff distance calculation). This process was automated through in-house developed software. Ongoing maintenance and quality control testing of the printer was implemented within the departmental QATrack+ system database. A consumable inventory system was implemented within our mould room.", "label": "poster"}
{"text": "Classification of Open Access Tupels 2,4,2,1,1 Green We want your Data! \u2192 Der Aufruf wirkt! Mittlerweile sind die Daten von 24 Institutionen im Datahub erfasst und abgebildet, das hei\u00dft 17 \u00f6ffentliche Universit\u00e4ten und ISTA + private Universit\u00e4ten, Fachhochschulen und Forschungsinstitute. Die abgebildeten Daten im Hub veranschaulichen einen sehr gro\u00dfen Teil der \u00f6sterreichischen, akademischen Publikationslandschaft. Open-Access-Anteile pro Jahr Publi- kation FIS / CRIS Teilprojekt 2 Austrian Datahub for Open Access Negotiations and Monitoring AT2OA2-Abschlussveranstaltung Universit\u00e4t Wien, 09.10.2024", "label": "poster"}
{"text": "GIO Structure (partial) The genetic interaction ontology (GIO) incorporating the genetic interactions structured terminology (GIST) Genetic Interaction: Phenotype Modification vs. Unexpected Whereas many published definitions of \u201cgenetic interaction\u201d assert that there must be a deviation from an expected double perturbation phenotype1-4, many examples of genetic interactions in the literature and in biological databases5-7 include phenotype modifications like suppression or enhancement that are not necessarily reported with an expected double perturbation trait value, precluding an analysis of expectation or deviation from it. For this reason, this genetic interaction ontology has two terms for genetic interaction distinguished by their meanings as either \u201csensu phenotype modification\u201d or \u201csensu unexpected\u201d. Both types of interactions provide meaningful insights into the biology of the genes in question, yet they have distinct sets of conclusions that can be drawn from them. This will be important for future curation and interpretation of genetic interactions catalogued by genetic interaction databases. References 1. Eddy SR. Genetics. Total information awareness for worm genetics. Science. 2006 Mar 10;311(5766):1381-2. PubMed PMID: 16527956. 2. Mani R, St Onge RP, Hartman JL 4th, Giaever G, Roth FP. Defining genetic interaction. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3461-6. doi: 10.1073/pnas.0712255105. Epub 2008 Feb 27. PubMed PMID: 18305163; PubMed Central PMCID: PMC2265146. 3. Dixon SJ, Costanzo M, Baryshnikova A, Andrews B, Boone C. Systematic mapping of genetic interaction networks. Annu Rev Genet. 2009;43:601-25. doi: 10.1146/annurev.genet.39.073003.114751. Review. PubMed PMID: 19712041. 4. Baryshnikova A, Costanzo M, Myers CL, Andrews B, Boone C. Genetic interaction networks: toward an understanding of heritability. Annu Rev Genomics Hum Genet. 2013;14:111-33. doi: 10.1146/annurev-genom-082509-141730. Epub 2013 Jun 26. Review. PubMed PMID: 23808365. 5. Harris TW, Arnaboldi V, Cain S, Chan J, Chen WJ, Cho J, Davis P, Gao S, Grove CA, Kishore R, Lee RYN, Muller HM, Nakamura C, Nuin P, Paulini M, Raciti D, Rodgers FH, Russell M, Schindelman G, Auken KV, Wang Q, Williams G, Wright AJ, Yook K, Howe KL, Schedl T, Stein L, Sternberg PW. WormBase: a modern Model Organism Information Resource. Nucleic Acids Res. 2020 Jan 8;48(D1):D762-D767. doi: 10.1093/nar/gkz920. PubMed PMID: 31642470. 6. Oughtred R, Stark C, Breitkreutz BJ, Rust J, Boucher L, Chang C, Kolas N, O'Donnell L, Leung G, McAdam R, Zhang F, Dolma S, Willems A, Coulombe-Huntington J, Chatr-Aryamontri A, Dolinski K, Tyers M. The BioGRID interaction database: 2019 update. Nucleic Acids Res. 2019 Jan 8;47(D1):D529-D541. doi: 10.1093/nar/gky1079. PubMed PMID: 30476227; PubMed Central PMCID: PMC6324058. 7. Thurmond J, Goodman JL, Strelets VB, Attrill H, Gramates LS, Marygold SJ, Matthews BB, Millburn G, Antonazzo G, Trovisco V, Kaufman TC, Calvi BR; FlyBase Consortium . FlyBase 2.0: the next generation. Nucleic Acids Res. 2019 Jan 8;47(D1):D759-D765. doi: 10.1093/nar/gky1003. PubMed PMID: 30364959; PubMed Central PMCID: PMC6323960. 8. Grove CA, Oughtred RW, Lee R, Dolinski K, Tyers M, Sternberg P, Baryshnikova A. Genetic Interactions Structured Terminology (GIST): A new standard for describing and annotating cross-species genetic interactions data. Biocuration 2017, Stanford University, Stanford CA. 9. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT, Harris MA, Hill DP, Issel-Tarver L, Kasarskis A, Lewis S, Matese JC, Richardson JE, Ringwald M, Rubin GM, Sherlock G. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 2000 May;25(1):25-9. PubMed PMID: 10802651; PubMed Central PMCID: PMC3037419. 10. The Gene Ontology Consortium. The Gene Ontology Resource: 20 years and still GOing strong. Nucleic Acids Res. 2019 Jan 8;47(D1):D330-D338. doi: 10.1093/nar/gky1055. PubMed ", "label": "poster"}
{"text": "Funded by the European Union Milestones to be delivered during the 2nd year of RD-Connect include the development of a centralised, searchable catalogue of registries, biobanks, and locus-specific database for rare diseases (M2.1) and the publication of guidelines for standardized access and operational workflow (M3.1). The catalogue is being developed in collaboration by WP2 and WP3. Sources : ORPHANET, EPIRARE, Treat-NMD, BBMRI, EuroBioBank, Telethon Network of Genetic Biobanks, among others. Searchable by: disease name, Orpha number, ICD-10, OMIM code, type of database, country. As compared to existing inventories, the RD- Connect catalogue should offer more detailed information on the content of each database (N of samples/registered cases for a certain disease) and be regularly updated by an automatic alert system and through the active participation of biobanks/registries. That would help researchers find information on the availability of the biomaterial/data they need and shorten the times required to achieve their research results. Also, the catalogue will promote networking interaction of its members. RD-Connect online catalogue of biobanks and registries: what do we add to the existing? Sabina Gainotti*, Paola Torreri*, Elena Bravo*, Domenica Taruscio*, Heimo Muller**, Robert Rehis**, Peter Abuja**, Gaelle Blandin***, Estrella Lopez****, Manuel Posada****, Marco Crimi*****, Lucia Monaco***** *Istituto Superiore di Sanit\u00e0, Rome, Italy; **Medical University of Graz, Austria; ***Univeristy of Marseille, France; **** Istituto de Salud Carlos III, Madrid, Spain; *****Telethon Foundation, Milan, Italy A template for a \u201cvisit/identity card\u201d (ID card) has been created for pilot biobanks and registries included in the catalogue, providing essential information that researchers may need to know when they consult the catalogue: Name of the database; name of the P.I. and contact person(s); hosting country; year of establishment; sources of funding; diseases covered; procedures used for quality control. P.I. or registries/biobanks contact persons will be invited to check their ID cards with the request to accept/deny inclusion into the RD-Connect catalogue, and to provide further detail about quality standards and accessibility of samples and information. In order to achieve this goal the design of the \u201cID-card\u201d will be based on proven Web 2.0/social media principles.", "label": "poster"}
{"text": "IODP Exp395: Reykjanes Mantle Convection and Climate Anita Di Chiara, Istituto Nazionale di Geofisica e Vulcanologia ..to reach the objectives of Expedition: 1) Oceanic crust: to test contrasting hypotheses for the formation of V-shaped ridges and troughs 2) Ocean circulation: to understand temporal changes in ocean circulation and explore connections with plume activity 3) Chemistry and hydrothermal circulation: to reconstruct the evolving chemistry of hydrothermal fluids with increasing crustal age and varying sediment thickness and crustal architecture. Fig.1 Bathymetry of North Atlantic Ocean. Black labels = Expedition 395 sites, gray labels = Expedition 384 and 395C sites, brown polygons = contourite drifts A transect over the North Atlantic.. \u2022 Expedition 395 (July-August 2023), following the previous Expedition 384 (July-August 2020) and Expedition 395C (July-August 2021), drilled a transect of a total of six sites in the Reykjanes Ridge (North Atlantic Ocean), southwest of Iceland (Fig.1). \u2022 Around the Reykjanes Ridge, the oceanic crust is characterized by a series of V-shaped ridges and troughs (Fig.2), whose origin is uncertain. \u2022 In the North Atlantic there are (contourite) sediments, deposited over the last 5 million year, which allow for reconstructing past Ocean circulation. Fig.2 Free-air gravity anomaly, red star = Iceland plume center, arrows = V-shaped ridges. A paleomagnetist job on the JOIDES Resolution: \u2022 Dating the sediments: As the marine sediments retain a record of the past magnetic field variations, a paleomagnetist can use these variations (magnetic polarity changes) to assign an age by comparing these magnetic polarity changes to a reference Geomagnetic Polarity Time scale. The oldest age of the recovered sediments is 32 million of years. \u2022 How? Measuring remanent magnetization in all the archive half-cores (Fig. 3A) and on discrete cubes (Fig. 3B) collected in the working half- cores. Fig.3. A) Measuring the half-core magnetization using the shipboard Superconducting Rock Magnetometer; B) Measuring discrete cubes with the JR6 magnetometer. (Photo credit Jen Field-Outreach Officer). A B", "label": "poster"}
{"text": "A comprehensive approach to computational mass spectrometry quality control Wout Bittremieux, Hanny Willems, Lennart Martens, Bart Goethals, Dirk Valkenborg and Kris Laukens biomina Pattern mining Due to the curse of dimensionality, specialized data mining techniques are required to detect patterns in the high-dimensional quality control data. Subspace mining: \u2022 Find a suitable subset of the original feature space by disregarding irrelevant dimensions \u2022 Within each subspace: clustering, outlier detection, \u2026 Subspace clustering: 1. Subspace detection: Cartification4 & frequent itemset mining5 2. Clustering in the detected (low-dimensional) subspaces Detected subspaces: \u2022 Related metrics: significant overlap with previous manually defined groups of co-occurring metrics \u2022 New relationships between metrics to be validated using expert knowledge Detected clusters: \u2022 Highly dependent on projected subspaces \u2022 Capture valid relationships between experiments (Figure 2) \u2022 Indicate faulty experimental results (Figure 3) Figure 2: Subspace clustering is able to detect rela5onships between metrics. For example, experiments that have a higher number of MS1 scans due to a higher MS1 collec5on frequency are clustered together. Figure 3: Clusters can be linked to instrument performance. For example, the highlighted cluster indicates experiments where no MS2 scans were collected due to a broken S-\u00ad\u2010lens. The awareness has risen that suitable quality control informa5on is mandatory to assess the validity of a mass spectrometry experiment. A complementary source of qualita5ve informa5on is available in the form of the mass spectrometer instrument seHngs, which provide addi5onal insights into the opera5onal characteris5cs of a mass spectrometer. Furthermore, we have developed specialized paJern mining algorithms to interpret this high-\u00ad\u2010dimensional data. The derived paJerns could subsequently be used to op5mize experimental design and mass spectrometry instrument seHngs. Conclusion Biomedical Informatics Research Center Antwerp (biomina) & Advanced Database Research and Modeling (ADReM) research group Department of Mathematics and Computer Science, University of Antwerp / Antwerp University Hospital, Belgium 1. Rudnick et al. (2010) Molecular & Cellular Proteomics 9:225\u2013241. 2. Ma et al. (2012) Analytical Chemistry 84:5845\u20135850. 3. Bittremieux et al. In preparation. 4. Aksehirli et al. (2013) ICDM \u201913 937\u2013942. 5. Naulaerts et al. (2013) Briefings in Bioinformatics. References wout.biJremieux@uantwerpen.be Instrument monitoring Advantages of monitoring instrument settings: \u2022 Can be directly related to the part of the instrument that is malfunctioning \u2022 Highly sensitive \u279e Small differences in instrument behavior will be rapidly detected Logging of external events that occurred to the mass spectrometer instrument: \u2022 E.g. calibrations, (periodic) maintenance, unexpected incidents, \u2026 \u2022 Vital information when interpreting the evolution of the instrument settings over the course of multiple experiments iMonDB: Instrument MONitoring DataBase \u2022 Tools to extract instrument settings from experimental raw files and store these in a database for longitudinal analysis \u2022 Tools to visualize instrument settings and to record structured information about external events (Figure 1) \u2022 API for use by developers \u2022 Tools, documentation and source code released as open source and freely available from: https://bitbucket.org/proteinspector/jmondb/ Figure 1: Instrument behavior can be monitored over 5me and can be related to external events. For example, the turbo pump of the mass spectrometer broke down, resul5ng in an increased power consump5on, and had to be replaced. Mass spectrometry quality control Quality control data = standardized quality control samples (e.g. BSA samples): \u2022 Extensive frequency: Periodically ran before, during, and after experimental samples \u279e Detect problems as soon as possible \u2022 Low complexity \u279e Limited variability Two sources of quality contro", "label": "poster"}
{"text": "CONOCIMIENTO PARTICIPATIVO -Producci\u00f3n de conocimiento nuevo -Beneficios personales y sociales -Avances para el conocimiento cient\u00edfico Insumos para la transformaci\u00f3n social TERRITORIO -Recurso natural -Espacio relacional -Dominaci\u00f3n pol\u00edtica -Representaci\u00f3n simb\u00f3lica -Territorio inmaterial Desigualdades socio- territoriales JUSTICIA AMBIENTAL Asimetr\u00edas en la toma de decisiones Movilizaci\u00f3n social y pol\u00edtica -Movimiento social -Desigualdad en la distribuci\u00f3n del riesgo ambiental Riesgo ambiental La producci\u00f3n de conocimiento participativo desde el territorio. Aportes para la justicia ambiental en la Cuenca Matanza-Riachuelo, Buenos Aires-Argentina Castro, Leticia y Arza, Valeria \u00bfDe qu\u00e9 manera la participaci\u00f3n social en la producci\u00f3n de conocimiento desde el territorio puede contribuir a impulsar soluciones que promuevan la justicia ambiental? CASO: CUENCA MATANZA RIACHUELO MARCO TE\u00d3RICO MATRIZ DE AN\u00c1LISIS DE CASOS EN PROCESO\u2026. -Habitada por m\u00e1s de 4,5 millones de personas -Abarca 14 municipios,9 comunas 64 km, 2047 km2 -Valorado como recurso natural y patrimonio hist\u00f3rico, arqueol\u00f3gico y cultural -Contaminaci\u00f3n de diversas fuentes: industriales, cloacales, residuos s\u00f3lidos, producci\u00f3n agropecuaria CAUSA MENDOZA ANTICIPANDO LA CRECIDA- Arroyo Dupuy Laferrere INATURALIST Biodiversidad en la CMR CUENCA EN RED- Biocorredor del Cilda\u00f1ez TERRITORIO RS AN AN sobre representaciones previas corredor bio-cultural de la CMR Cuenca-Biocorredor- Red DESIGUALDAD P P P selecci\u00f3n de m\u00e1s barrios afectados subcuencas; vulnerabilidad social zona Sudoeste de la CABA (Comunas 8 y 9) ASIMETR\u00cdA EN LA TOMA DE DECISIONES RS RS AN asesoramiento a la gesti\u00f3n, jerarquizaci\u00f3n de actores comunitarios participaci\u00f3n ciudadana-gestion responsable y sostenible gesti\u00f3n asociada RIESGO AMBIENTAL RS AN P medici\u00f3n y concientizaci\u00f3n sobre percepciones previas involucramiento y concientizaci\u00f3n factores de contaminaci\u00f3n, contra el entubamiento MOVILIZACI\u00d3N RS P RS trabajo con redes preexistentes \u00e9nfasis en la participaci\u00f3n ciudadana participaci\u00f3n institucionalizada CONOCIMIENTO AN AN AN complementariedad de fuentes de datos crowdsourcing-grandes vol\u00famenes de datos sobre el patrimonio enfoque transdisciplinario INSUMOS PARA LA TRANSFORMACI\u00d3N AN AN AN para los sistemas de alerta temprana medici\u00f3n/reconocimient o de la biodiversidad para propuesta de corredor dise\u00f1o de proyecto. orientaci\u00f3n a la gesti\u00f3n -Entrevistas semi-estructuradas para conocer las percepciones de los beneficios personales, sociales y cient\u00edficos de estas experiencias de conocimiento participativo -Fallo de la CSJN-2008 -Ordena la recomposici\u00f3n ambiental -Se instala como uno de los principales conflictos socio-ambientales del pa\u00eds This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA. Referencias: AN- Aporte novedoso P- Problematizaci\u00f3n RS-Resignificaci\u00f3n", "label": "poster"}
{"text": "SI2-SSE: Foundations for as an Extensible Tool for Power Systems Research and Education Ray Zimmerman, Cornell University The information, data, or work presented herein was funded in part by the National Science Foundation (NSF), under Award Number 1642341. The views and opinions expressed herein do not necessarily state or reflect those of the United States Government or any agency thereof. What is MATPOWER? \u2022 Set of free, open-source, Matlab language tools compatible with MATLAB\u00ae and GNU Octave \u2022 For steady-state power system simulation and optimization, including: \u2022 power flow (PF) \u2022 continuation power flow (CPF) \u2022 extensible, optimal power flow (OPF) \u2022 unit commitment (UC) \u2022 stochastic, secure multi-interval OPF/UC. MATPOWER Websites http://www.pserc.cornell.edu/matpower/ https://github.com/MATPOWER/matpower MATPOWER\u2019s Unique Combination \u2022 free, open-source license (BSD) \u2022 code that is easy to understand, customize \u2022 state-of-the-art, high performance solvers \u2022 ready-to-use realistic data included MATPOWER boosted to de facto standard \u2022 benchmark platform for power systems research \u2022 educational tool for power systems engineers and optimization What is MATPOWER? MATPOWER Core Software MATPOWER already provides robust and flexible implementations of power flow (PF) and optimal power flow (OPF), some of the most foundational problems in power systems operation and planning. Redesign core software around a general modular architecture to enable more flexible user customization and facilitate significant user contributions, while retaining and enhancing the simplicity that makes it attractive in education. To enable: \u2022 new device types (3-winding transformers, FACTS, etc.) \u2022 new power flow and optimal power flow controls \u2022 foundation for 3-phase unbalanced models for distribution networks Project Summary Expand MATPOWER\u2019s future impact as a successful research-enabling tool for the problems of the power systems of the future by providing the project infrastructure and core software architecture needed to facilitate ongoing community-supported growth. Project Overview MATP WER MATPOWER Project Infrastructure Transition to fully open collaborative development paradigm with \u2022 public code repository (GitHub) \u2022 issue tracker (GitHub) \u2022 documentation \u2022 user and developer forums \u2022 contributor guidelines \u2022 public list of project descriptions MATPOWER Project Infrastructure MATPOWER Core Software Architecture MATPOWER Core Software MATPOWER is a research-enabling tool, used worldwide in teaching, research and industry. It\u2019s growing momentum and impact are evidenced by \u2022 more than 2,500 citations* of 2011 MATPOWER paper [1] \u2022 more than 20,000 downloads per year (> 156,000 total) 2557 total citations (*according to Google Scholar 4/19/18) [1] R. D. Zimmerman, C. E. Murillo-S\u00e1nchez, and R. J. Thomas, \u201cMATPOWER: Steady-State Operations, Planning and Analysis Tools for Power Systems Research and Education,\u201d Power Systems, IEEE Transactions on, vol. 26, no. 1, pp. 12-19, Feb. 2011. [2] C. E. Murillo-S\u00e1nchez, R. D. Zimmerman, C. L. Anderson, and R. J. Thomas, \u201cSecure Planning and Operations of Systems with Stochastic Sources, Energy Storage and Active Demand,\u201d Smart Grid, IEEE Transactions on, vol. 4, no. 4, pp. 2220- 2229, Dec. 2013. [3] A. J. Lamadrid, D. Mu\u00f1oz-\u00c1lvarez, C. E. Murillo-S\u00e1nchez, R. D. Zimmerman, H. Shin, R. J. Thomas \u201cUsing the MATPOWER Optimal Scheduling Tool to Test Power System Operation Methodologies Under Uncertainty,\u201d Sustainable Energy , IEEE Transactions on, revise and resubmit. MATPOWER Impact 0 100 200 300 400 500 600 700 2011 2012 2013 2014 2015 2016 2017 2018 Annual Citations of MATPOWER Paper 0 2000 4000 6000 8000 10000 12000 14000 16000 18000 20000 22000 24000 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 Annual MATPOWER Downloads by Version 6.0 5.1 5.0 4.1 4.0 3.2 3.0 2.0 1.0 MATPOWER Core Software MATPOWER 7.0 \u2013 first beta release imminent \u2022 Three new power flow algorithms for radi", "label": "poster"}
{"text": "Assessing the Problem The Undergraduate Learning & Community Center ULCC A day at the Rohan Kapoor & Tamana Ranka Faculty Advisor: Connie Hanel The foundation of the center\u2019s success is twofold; first the environment created by the undergraduate school of management presents an inviting space exciting space that welcomes students in while providing supportive work stations, the next key component are the tutors that welcome and embrace our students with positive energy as they share their knowledge to promote individual success. What is the ULCC? The ULCC offers tutoring in all 7 of the School of Management prerequisite courses. \u2022 ECO 181 \u2013 Macroeconomics \u2022 ECO 182 \u2013 Microeconomics \u2022 MGA 201 \u2013 Introduction to Financial Accounting \u2022 MGA 202 \u2013 Introduction to Management Accounting \u2022 MGQ 201 \u2013 Introduction to Statistics for Analytics \u2022 PSY 101 \u2013 Introductory Psychology \u2022 Mathematics \u2013 PreCalculus and Calculus Whether you\u2019re struggling with fundamentals or just want to boost your GPA, tutors are center-certified and here to help you meet your academic goals. If English is not your first language and you want to strengthen your communication skills, an ESL Coach is also available. ULCC tutors possess a GPA of 3.5 or higher in their designated course(s) and go through vigorous training including 10 hours of new hire training session, as well as a FERPA tutorial on maintaining confidentiality. Located in the lower level of the Jacobs Management Center, the Undergraduate Learning and Community Center includes three classrooms, a community area, tutoring facilities and a group study area all dedicated exclusively to our undergraduates, with technology throughout to enhance their experience. The project was made possible by a $500,000 lead gift from Frank, BS '66, and Marilyn Clement, with matching funding from the UB Provost's Office and an additional anonymous contribution. ULCC is place where students can walk in and feel excited to be a part of a learning and community Hub. Tutoring at the ULCC Sept. Oct. Nov. Dec. Fall Total Jan. Feb. Community Area 984 1102 815 730 3631 117 989 Learning Center & Tutoring 172 220 167 61 620 9 358 Total: 1156 1340 1000 796 4292 126 1338 The ULCC Success Story Connie Hanel Manager, ULCC", "label": "poster"}
{"text": "RADseq phylogenetic inferences using de novo downstream analyses as compared to single gene sequencing of the ectomycorrhizal fungus Cenococcum geophilum Jessica M. V\u00e9lez1,2, Todd W. Pierson7, Reese M. Morris1, Steven J. Lebreux1, Jessy Labbe1, Luz M. Serrato-Diaz5, Rytas Vilgalys3, Scott J. Emrich4, Christopher W. Schadt1,2,6,* 1Oak Ridge National Laboratory, 2The Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee, 3Duke University, 4Min H. Kao Dept of Electrical Engineering and Computer Science, University of Tennessee, 5University of Puerto Rico - R\u00edo Piedras Campus, 6Department of Microbiology, University of Tennessee, 7Department. of Ecology and Evolutionary Biology, University of Tennessee \u2022 Agricultural security is essential to economic security. \u2022 A significant portion of land is contaminated with heavy metals. \u2022 Biofuel crops such as Poplar could be planted instead. \u2022 Increasing the ability of Poplar to grow in these areas increases the potential for agricultural development and can remediate the land. \u2022 A soil symbiont may be able to increase heavy metal tolerance. \u2022 The ubiquitous and hardy fungus Cenococcum geophilum will be studied to determine if this species can increase Poplar heavy metal tolerance. \u2022 The genetic complexity of C. geophilum promotes the use of the novel ddRAD-seq technique. BACKGROUND The fungal species Cenococcum geophilum, an ubiquitously distributed ectomycorrhizal fungus which is positively associated with plant health, growth, and increased contaminant resistance. This fungus is known to associate with both angiosperm and gymnosperm tree species across 40 genera, representing over 200 total species, and is generally tolerant across a salinity gradient, water stress conditions, and extreme heavy metal contamination conditions. This wide-ranging resistance to stressful conditions in a soil environment is often attributed to a high melanin content, as C. geophilum is phenotypically deep black in coloring. This high concentration of melanin has been directly implicated to play a role in increased resistance to heavy metal contaminants. The genome of C. geophilum is among the largest in the fungal kingdom, with a mapped size of 178 Mbp and a total estimated size of up to 203 Mbp. Cenococcum geophilum has no documented sexual or asexual spore production, and is considered asexual as a species despite high levels of genetic and physiological diversity. Due to these high levels of intraspecies diversity found among C. geophilum isolates, even within isolates from a single tree, C. geophilum is proposed to be a species complex, with many studies finding significant variations in cultured isolate characteristics and physiology. This type of cryptic species population implicates the incorporation of morphologically identical members which are separate species on the genetic level. As a result, while C. geophilum appears to have a myriad of potential benefits for agricultural applications, this fungus has been difficult to study phylogenetically, as this research is necessarily resource-intensive in order to delineate the phylogenetic relationships observed within the species complex. Cenococcum geophilum SINGLE GENE versus RADseq DE NOVO ASSEMBLY 231 unique strains were isolated from 60 sites, with a total geographic range of 283 miles from central Oregon to northern Washington State. A maximum likelihood phylogeny of the Pacific Northwest isolates (left) using the glyceraldehyde 3-phosphate dehydrogenase (GAPDH) gene region revealed 15 strongly resolved (>80%) clades (numbered). Fifteen well-supported clades (>80%) were implicated within the RADseq dataset (right). Generally, there is a negative correlation (r = -0.82) between the de novo cluster and the clade assigned based on the GAPDH gene. However, when the largest GAPDH clades, 10 and 11, are examined separately, there is a positive correlation (r = 0.70) between the de novo assigned clade and the clad", "label": "poster"}
{"text": "GLOBAL ANALYSIS Two density peaks for winter and summer SST Progressive widening of the curve towards the high/maximum values Higher positive trend in the Eastern Mediterranean basin Mean Mediterranean SST time series SST daily trend 1982-2019 The Mediterranean, almost 40 years of continued warming Global density plot Mean Mediterranean SST presents a warming trend since the 80s of the XX century to the present time but with a strong seasonal component that can mask actual trend Positive trend for the global mean SST with the higher warming rate in the Eastern Mediterranean basin and the lower trend in the Central Mediterrane- an basin (south of Italy) REGIONAL TREND ANALYSIS SST trend component Positive trend for all quantiles for global Mediterranean Accelerated warming for 75 and upper quantiles than in lower quantiles Highest quantile trend for 75 quantile in the Western Mediterranean SST trend quantiles time series Three different zones regarding daily warming trend for SST: Western, Central and Eastern Mediterranean basins. Highest values in the Eastern basin and the northern half of the Western basin Lower values in the Central Mediterranean basin \u2022 Mediterranean SST has been consistently warming since the 80\u2019s \u2022 Warming presents spatial variability, being higher in the Eastern Med basin \u2022 Warming made up of a higher \u201cmost frequent SST\u201d rather than an incre- ment of extreme values \u2022 Positive warming trend in the whole Mediterranean basin \u2022 Highest trend in most of the Eastern basin and northern half of the West- ern basin, lowest but still positive trend in the Central Mediterranean CONCLUSIONS Francisco Pastor Meteorology and Pollutant Dynamics Area Fundaci\u00f3n CEAM (Spain) Website: http://www.ceam.es/SST This work is part of the research project VERSUS CGL2015-67466-R (MICINN/FEDER), funded by the Spanish R&D&I national plan of Spanish Ministry of Science, Innovation and Universities and European Regional Development Fund and the IMAGINA-PROMETEO (PROMETEU/2019/110) fund- ed by the Generalitat Valenciana. Data source GHRSST Level 4 AVHRR_OI Global Blended Sea Surface Temperature Analysis (GDS ver- sion 2) from NCEI obtained from PODAAC (https://podaac.jpl.nasa.gov/dataset/AVHRR_OI- NCEI-L4-GLOB-v2.0)", "label": "poster"}
{"text": "www.p4play.eu @P4Play_EU Fiona Loudoun, Ines Wenger, Supervisors: Dr Bryan Boyle, Prof Maria Larsson-Lund, Dr Maria Prellwitz, Dr Helen Lynch, Prof Christina Schulze References: 1. Stephen, C., & Plowman, L. (2014). Digital Play. In L. Brooker, M. Blaise, & S. Edwards (Eds.), Sage Handbook of Play and Learning in Early Childhood (pp. 330\u2013341). Sage Publications Ltd. 2. Waller, G., Suter, L., Bernath, J., K\u00fclling, C., Willemse, I., Martel, N. & S\u00fcss, D. (2019). MIKE \u2013 Medien, Interaktion, Kinder, Eltern: Ergebnisbericht zur MIKE-Studie 2019. Z\u00fcrich: Z\u00fcrcher Hochschule f\u00fcr An-gewandte Wissenschaften. 2. Moore A, Lynch H. Accessibility and usability of playground environments for children under 12: A scoping review. Scandinavian Journal of Occupational Therapy. 2015;22(5):331\u201344. 3. Prellwitz M, Sk\u00e4r L. Usability of playgrounds for children with different abilities. Occupational Therapy International. 2007;14(3):144\u201355. 4. Green, L., Holloway, D., Stevenson, K., Leaver, T., & Haddon, L. (2021). The Routledge Companion to Digital Media and Children; First Edition. 5. \u2018Boy Playing on Ground\u2018 by Jiawei Cui is licensed under Pexels License. 6. \u2018Girl and Boy Playing on Tablet Device\u2019 by Alex Green is licensed under Pexels License. 7. \u2018Globe image\u2019 licensed under pinclipart.com This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under the Marie Sk\u0142odowska-Curie grant agreement No: 861257. These two projects are anchored in the concept of PLACES exploring children\u2019s participation in play in digital spaces and the design of community play spaces incorporating universal design and natural elements. P4PLAY: RESEARCHING PEOPLE, PLACE, POLICY and PRACTICE for PLAY from the LENS of OCCUPATIONAL SCIENCE Oh\u2019 The Places You\u2019ll Go: Adventures Outdoors and in Digital Playgrounds Background The P4Play Marie Sklodowska-Curie (MSC) Training Network is an innovative European Joint Doctorate (EJD) programme in Occupational Science for Occupational Therapists. This EJD was established in 2020 when 2.2 m was awarded to a consortium of researchers and play advocates, in the highly competitive Horizon2020 scheme. P4play is a collaboration between 4 academic universities in Ireland, Sweden, Scotland, and Switzerland, and 15 partner organisations in Europe and the USA. The P4play programme adopts a child's rights-based perspective and aims to investigate the nature of play through the lens of People, Place, Policy and Practice (P4Play). A refocus on play as a right requires further study as a central concern (or occupation) in children's lives. Occupational Science, a science dedicated to the study of humans as doers or as occupational beings, offers a unique lens to explore play as an occupation. Methodology The centrality of participation is acknowledged by positioning children as active and agentic individuals with a to right to engage in play (4). By conceptualising children as the holder of rights, participatory methods will be utilised throughout the research to explore children\u2019s experiences and subjective understanding of play outdoors and in digital spaces. Play in Digital Spaces A scoping review will be initially conducted to identify and examine the literature exploring children\u2019s perspectives of play in digital spaces for children from infancy through to adolescence. This research will consist of 3 participatory studies which will involve children across the trajectory of childhood. Age appropriate methodologies such as observation, photo-elicitation interviews, and storyboard collage groups will be used throughout data collection. Play in Outdoor Play Spaces This research will consist of four studies, investigating the perceptions of playground users (children with and without disabilities aged 7-12 years and their parents), playground builders (e.g. architects, landscape architects), and experts of Universal Design regarding inclusive playgrounds through multiple methods (interviews, focus ", "label": "poster"}
{"text": "in 2013 and 2015, respectively. He is currently a Marie Sk\u0142odowska-Curie research fellow. His research topic is the development of driver distraction detection and human-machine interface evaluation methods for multi-actuated ground vehicles. His research interests include human-machine interface, fuzzy systems, machine learning, vehicle safety, ADAS. A novel robust driver distraction detection and evaluation algorithm based on machine learning and fuzzy theory combination is developed. Driver-in-the-loop experiment with Skoda Auto facilities (advance testing of driver decoy workshop) and in cooperation with IPG Automotive GmbH (Secondment 1; 3 month). Publications: \u201cDriver distraction while performing a secondary task evaluation approach based on fuzzy expert system\u201d, 10th Graz Symposium 2017. \u201cA Method of Driver Distraction Evaluation Using Fuzzy Logic\u201d, IEEE ICAT 2017. \u201cDesign of Regenerative Anti\u2212lock Braking System Controller for 4 In\u2212Wheel\u2212Motor Drive Electric Vehicle with Road Surface Estimation\u201d, TBD \u201cDetection and Evaluation of Driver Distraction Using Machine Learning and Fuzzy Logic\u201d, TBD \u201cDriver performance prediction by solving regression analysis\u201d, TBD \u201cInduced by In-Vehicle Information System Driver Distraction Detection and Evaluation Method\u201d, TBD \u201cDriver performance prediction with regression analysis\u201d, TBD Interdisciplinary Training Network in Multi-Actuated Ground Vehicles DRIVER ASSISTANCE MEASURE FOR LOW-EMISSION MAGV https://iteam-project.net CONTACT INFO FUTURE STEPS OUTCOMES PROGRESS ACHIEVED ESR 08: Andrei Aksjonov, MSc. \u0160KODA Auto a.s. | Concept Development | Volkswagen Group T\u0159. V\u00e1clava Klementa 869, 293 01 Mlad\u00e1 Boleslav II, Czech Republic +420 734 249 830 | andrei.aksjonov@skoda-auto.cz ACKNOWLEDGEMENT This Research receives funding from the European Community Horizon 2020 Framework Programme under grant agreement No. 675999. \u00b7 Development method of testing and assessment the secondary task impact to the safe vehicle operation, which is exploited for different human-machine interaction technologies comparison and as a benchmark for safe and clear in-vehicle information system design with minimal driver\u2019s burden; \u00b7 Development software tool for on-board simulation driver decoy on in-vehicle secondary task execution; \u00b7 Verification simulation results with respect to correctness and completeness on the advanced driving simulator based on a real vehicle platform with identical control elements like steering wheel, pedals, 3D scene and consistent road topology with real test field. Host institution: \u0160KODA Auto a.s. Primary supervisor: Pavel Nedoma, PhD Secondary supervisor: Zden\u011bk Franc, MSc Planned secondments: IPG Automotive GmbH (3 month); Universit\u00e0 degli studi di Pavia (2 month) MSc. Andrei Aksjonov OBJECTIVES AND WORK PLAN Andrei Aksjonov received his BSc and MSc in electrical drives and power electronics with automation specialization from Tallinn University of Technology The method capable not only to detect driver distraction induced by secondary activity, but also to evaluate its impact on traffic safety is developed. The algorithm operates as follows: vDesign each individual driver normal driving model using machine learning (ANFIS, ANN, ED, k-NN); vPredict driver behavior and compare it with driver distraction lap; vEvaluate (fuzzy logic) level of driver distraction based on vehicle dynamic performance. Predictor dx dv Vl r dvp dxp dvr dxr DD \uf0ee \uf0ed \uf0ec \uf03c \uf02d \uf03e \uf03d dv dv dv dv dv dv dv p p p r , ,0 \uf0ee \uf0ed \uf0ec \uf03c \uf02d \uf03e \uf03d dx dx dx dx dx dx dx p p p r , ,0 Driver Vehicle Environment Dynamics Performance Distraction detection Secondary task Actuation Performance prediction Road Elaboration of the driver advisory functions related to the vehicle and traffic safety improvement, emission reduction and energy-efficiency increase. These functions will be realized in human-machine interface (HMI) systems with visual and haptic channels supporting interactions between the driver and on-board systems of Multi-Actuated G", "label": "poster"}
{"text": "Recovery of TESS Stellar Rotation Periods with Convolutional Neural Networks Zach Claytor and Jennifer van Saders Institute for Astronomy, University of Hawai\u02bbi Conv2D MaxPool2D Dense x3 x2 We train our network on wavelet power spectra of simulated light curves with real TESS systematics, then predict both the rotation period and its uncertainty. Predicting the period uncertainty lets us select objects with more confident estimates. With this selection, we recovery 60% of objects\u2019 periods to within 10% accuracy. TESS period recovery efforts are confounded by mission systematics. But can neural networks see through the noise? zclaytor@hawaii.edu @AstroClayt zclaytor \u25cfNNs can \u201clearn\u201d the noise and ignore it to some extent. \u25cfWe are currently testing our network on a number of simulated and real light curves. \u25cfLook for this on the arXiv in the coming weeks!", "label": "poster"}
{"text": "Backfilling the Maxwell HPC User demands on resources the Maxwell HPC cluster correlates with the data taking of the EuXFEL and photon experiments on site. During low demand, we backfill sections of the cluster with opportunistic grid jobs through a dedicated ARC CE. As demand can change quickly and for data taking responsiveness is crucial, evacuation time has to be in the order of seconds. Authentification As users require long-running jobs over several days and rely on their AFS-HOME directories as well as scratch and long-term storage mounted over NFSv4, token handling is crucial. We implemented a token renewal service to allow for such long-running jobs to access the mounted network home directories over their whole lifetime. Chaining Storage and High-Throughput Computing to each other Event-driven Automatised Workflows and FaaS-Offloading Consolidating the interactive analysis and Grid infrastructure at DESY. Classic workflow engines rely primarily on \u201cpolling\u201d the different states in their connected systems such as storage instances and compute clusters. In contrast event based workflows allow for a \u201cpush\u201d approach, where different actions can be combined, chained and forked to powerful workflows. To integrate various systems into such a workflow engine, a common message bus for exchanging events as well as a function registry for acting on events is needed. With dCache Storage Events as prime example [4], we are working on combining our storage instances and offline computing resources into one workflow environment, e.g., to allow new files to automatically initiate their own processing as for calibration tasks. Here, a dCache instance creates for each file change a Storage Event and relays it over the Kafka bus. To react on matching events and initiated further actions, functions are registered in a dynamically scalable OpenWhisk Function-As-A-Service platform. However, FaaS lambdas are intended as primarily low-latency, fast processing programs with a standardised API, we are working on offloading the actual heavy processing tasks via functioninalised remote submission to our HTCondor batch system. Combined with anonymous jobs, this allows for dynamically scaling out to computing resources. Anonymous Jobs with Authorization Tokens While classical jobs run under a user ID and read files belonging to such an user ID, this requires a common global identify namespace over all involved resources. Moving from authentication to an authorisation based resource control will allow to be more secure and especially flexible with function workflows. In a token-based scheme, only a central token generator and authentication instance is be needed. Here, a lambda token generator is the only compute instance matching an identity to resources. On a matching event, it request on behalf of the ID authorisation tokens from the storage and compute elements. The tokens can be strictly limited to the needs of the actual processing event, e.g., requesting from a dCache instance read-only Macaroon tokens [4] for input files and limit write abilities to a confined output path. Similarly a submit token to the HTCondor batch system might be requested and added to the compute event. The aim is for a self-sufficient event, that includes as tokens all necessary file inputs and outputs as well as compute resources. Followingly, a compute job based on such a self-sufficient event could run locally under an anonymous user and stage files in/out by its Macaroons. Such an anonymous job could also be scaled out to other compute resources, as it is decoupled from the inital ID namespace. Anonymous Job File I/O Macaroon LRMS Token predef. Fcn/Job f(x) LRMS Storage Storage { \"read\": { \"path\": \"/pnfs/.../myinfile.root\", \"macaroon\": \"MDAx...97MK\", \"endpoint\": \"https://dcache-door.in:2880\" }, \"write\": { \"path\": \"/pnfs/.../output.d\", \"macaroon\": \"MDAx...5JCg\", \"endpoint\": \"https://dcache-door.out:2880\" } \"exec\": { \"function\": \"my_fcn_ns.my_reprocessing_fcn\" }, ", "label": "poster"}
{"text": "The toxicity testing experiments resulted in a final list of 22 compounds that interfered with development of the neuromasts. Example Results of Toxicity Testing Many industrial chemicals are released into the environment every year without a full assessment of their adverse effects on human life and the ecosystem. We are in urgent need of new screening methods that are rapid and can predict toxicity across species. We aim to understand the developmental toxicity effects of some of these environmental pollutants on the zebrafish posterior lateral line which is made up of neuromasts. Zebrafish, like other fish species, use their neuromasts to sense water flow. Introduction Acknowledgements \u2022 This research was funded by National Institute of Health (P30ES023512). \u2022 The transgenic fish (GW57A) were obtained from Vladimir Korzh Institute of Molecular and Cell Biology (IMCB), Singapore References Gallardo, V. E. et al. Phenotype-driven chemical screening in zebrafish for compounds that inhibit collective cell migration identifies multiple pathways potentially involved in metastatic invasion. Disease models & mechanisms 8, 565-576, doi:10.1242/dmm.018689 (2015) The views expressed may not reflect US EPA policy Conclusions/Future Directions \u2022 We developed a method for rapid screening of large number of chemicals to identify zebrafish neuromast disruptors. \u2022 We identified serotonin as a possible pathway being targeted by the disruptors which we confirmed through some preliminary experiments. \u2022 We theorize that Serotonin doesn\u2019t only regulate mood, but also plays a role in cell proliferation/motility. Our next step would be to test the newly identified serotonin effectors on different cancer cell lines to better understand the role of serotonin in cancer metastasis. Serotonin http://tobeagenius.tumblr.com/tagged/infographic \u2022 Zebrafish embryos expressing green fluorescence in neuromasts were exposed to ~300 pesticides/antimicrobials at 3 concentrations within hours of being fertilized. \u2022 After 4 days of exposure to the chemicals, the embryos were imaged and analyzed. \u2022 All chemical testing was completed within 6 months. Methods and Results High Throughput and Follow-up Screens *dpf \u2013 days post fertilization; **hpf \u2013 hours post fertilization Testing Serotonin Effectors on Neuromast Development https://sapiensoup.com/serotonin Gilmour Group \u2013 Eu. Mol. Bio. Laboratory Monroe et al. \u2013 Front. Cell. Neurosci., 2015 Rachna Mirchandani1, Savini Thrikawala1, Cliff Stephan2, Nghi Nguyen2, Mary Sobieski2, Richard S Judson3, Jan-\u00c5ke Gustafsson1, Maria Bondesson4 1Dept. of Biology and Biochemistry, University of Houston 2Center for Translational Cancer Research, IBT 3National Center for Computational Toxicology, US EPA 4Intelligent Systems Engineering, Indiana University Developing the Zebrafish Neuromast Assay as a Predictive Toxicity Model Andr\u00e9 K\u00fcnzelmann, UFZ", "label": "poster"}
{"text": "Title: Subtitle Leeroy Jenkins, author2, author3, author4 ! ! Can we understand exoplanets better if we use both high res spectra and direct images in a machine learning pipeline? Simultaneous detection and characterization of exoplanets using machine learning Rakesh Nath (rakesh.nath@uliege.be), Olivier Absil \u03b7 = 0.01 Obtain raw cube for consisting of images and spectra \u2022 Use a 1DCNN to discriminate between spectra with and without plane. \u2022 Use a deep MLP to regress to ! and ! log(g) Teff 1. Measure the spectrum for each spaxel and normalize by total 2. Compute a reference spectrum and divide it out of the bins 3. Compute PCA and subtract most of the stellar components from the spectrum. HIGH CONTRAST IMAGING HIGH RESOLUTION SPECTROGRAPHY MACHINE LEARNING \u03b7 = 0.1 Exoplanet detection and characterisation are typically conducted independently. In principle, however, complete information of the diversity in exoplanetary systems cannot be captured by either method independently. A number of recent papers have combined detection and characterisation simultaneously(Hoeijmakers et al 2016 etc.). However, these papers have only combined both detection and characterisation by processing the same data through independent methods. Therefore there is a need to combine these co-dependent techniques using a common pipeline. We phrase the detection of planet using pure spectra as a classification problem. We use synthetic data to train a 1D CNN. The hypothesis equation is defined as ! Where ! if a planet is present. We use the Pickles catalog to generate ! of G-M type stars and the BT-SETTL Ames to generate ! of planets with ! . We have tested this for different values of contrast ! . If a planet is detected then we feed the spectra to an MLP to regress to ! . F(\u03bb) = F\u22c6(\u03bb) + \u03bcFp(\u03bb) \u03bc = 1 F\u22c6(\u03bb) Fp(\u03bb) 800 < Teff < 1200K \u03b7 (Teff, log(g)) INTRODUCTION METHODS Regress to ! , completed training, testing in progress Combine the disparate steps into a single integrated pipeline HCI+new data from Keck planetary imager and characteriser (KPIC) (Teff, log(g)) RESULTS NEXT STEPS ML Crosscorrelation", "label": "poster"}
{"text": "#1.40 - DETERMINANTES DE RENDIMIENTO EN EL JUEGO DE CARTAS DE PERCEPCI\u00d3N VISUAL \"SET\" de la Hera, Diego Pablo1,*; Rosso, Anah\u00ed2; Roulet, Nicol\u00e1s2; Sigman, Mariano1; Calero, Cecilia In\u00e9s1 1. Laboratorio de Neurociencia, UTDT - CONICET; 2. FCEN, Universidad de Buenos Aires * delahera@gmail.com http://cor.to/aacc19 \u00a1Llev\u00e1 una copia! CLASIFICACI\u00d3N 1x PR\u00c1CTICA 3x PRUEBA 10 40 40 40 * SUBTIPO: ATRIBUTO EXTRA\u00d1O forma color textura n\u00famero 4 atributos EL JUEGO \u00a9 2017 Set Enterprises, Inc. EJEMPLOS (NoSet) (Set) Set 1-diferente 2-diferente 3-diferente 4-diferente i- 1-roto 2-roto 3-roto 4-roto i- NoSet forma diferente color diferente textura diferente n\u00famero diferente forma igual color igual textura igual n\u00famero igual forma rota color roto textura rota n\u00famero roto forma sana * color sano textura sana n\u00famero sano TIPO SUBTIPO ATRIBUTO EXTRA\u00d1O si para todos y cada atributo REGLA SET \u00f3 (igual) (diferente) * sano = no roto METODOLOG\u00cdA 1 2 3 A B C La identificaci\u00f3n correcta de NoSets es m\u00e1s r\u00e1pida que la de Sets. La identificaci\u00f3n de NoSets es m\u00e1s r\u00e1pida cuanto mayor es el n\u00famero de atributos rotos. La identificaci\u00f3n de Sets es m\u00e1s r\u00e1pida cuanto menor es el n\u00famero de atributos diferentes. Los ejercicios tipo Set son m\u00e1s f\u00e1ciles de identificar correctamente. Muestra: 30 j\u00f3venes adultos universitarios (rptas correctas \u2265 80%, n=26) 3 cartas por ejercicio. Responder Set/NoSet con teclado. 10 segundos m\u00e1ximo por ejercicio. Feedback en respuestas incorrectas 10 ejercicios de pr\u00e1ctica 120 ejercicios de prueba, divididos en 3 bloques 10 ejs. - 1 Set 4-dif. - 2 Set 1-dif. - 2 Set 3-dif. - 5 NoSet (al azar) 120 ejs., 40 por bloque - 6 Set 4-dif. - 6 x 4 Set 1-dif. - 6 x 4 Set 3-dif. - 2 x 6 Set 2-dif. - 54 NoSet (al azar) m\u00e1s lento m\u00e1s r\u00e1pido Si s\u00f3lo un atributo es diferente, es preferible que sea el color o el n\u00famero, frente a la textura. Si s\u00f3lo un atributo est\u00e1 sano, es preferible que sea la textura o la forma, frente al n\u00famero. Si s\u00f3lo un atributo es igual, es preferible que sea el n\u00famero o la textura, frente al color o la forma. Identificar factores perceptuales y cognitivos que modulan la identificaci\u00f3n de Sets y NoSets. Comparar: (i) Sets vs NoSets, (ii) Sets en funci\u00f3n del n\u00famero de atributos diferentes, (iii) NoSets en funci\u00f3n del n\u00famero de atributos rotos, y (iv) la saliencia perceptual de los atributos. OBJETIVOS ACIERTOS TIEMPO DE RESPUESTA (respuestas correctas) SALIENCIA DE ATRIBUTOS Set NoSet i si para al menos un atributo (roto) REGLA SET * z-score por subtipo * Test del signo Test t pareado Set 1-diferente (atributo diferente) ejemplos ilustrativos Set 3-diferente log(rt) z-score * (atributo igual) ejemplos ilustrativos log(rt) z-score * ejemplos ilustrativos Set i-diferente 0 p<.001 Modelo mixto NoSet i-roto 0 p<.001 ejemplos ilustrativos Modelo mixto NoSet 3-roto log(rt) z-score * (atributo sano) ejemplos ilustrativos ANOVA + Tukey SET es un juego de cartas de percepci\u00f3n visual, desarrollado en 1974 por la genetista de poblaciones Marsha Falco. Aunque su estructura ha motivado varios estudios en el campo de las matem\u00e1ticas1, sus caracter\u00edsticas cognitivas y perceptuales no han sido estudiadas en la misma profundidad2,3. En este trabajo examinamos factores que modulan el desempe\u00f1o en el juego SET, con el objetivo de caracterizar este paradigma para su uso en nuestros estudios sobre ense\u00f1anza entre pares. CONCLUSIONES - Los ejercicios tipo Set son m\u00e1s f\u00e1ciles de identificar. - La identificaci\u00f3n correcta de NoSets es m\u00e1s r\u00e1pida que la de Sets. - En Sets, la diferencia es m\u00e1s demandante que la igualdad. - En NoSets, el n\u00famero de atributos rotos acelera la identificaci\u00f3n. - Describimos saliencia relativa de atributos en distintos contextos. Las barras de error en los gr\u00e1ficos de barras, y las bandas transl\u00facidas en los gr\u00e1ficos de dispersi\u00f3n, representan intervalos de confianza del 95% obtenidos con el m\u00e9todo bootstrap de remuestreo. *: p < .05, **: p < .01, ***: p < .001. Se verific\u00f3 el cumplimiento de todos los supuestos de las pruebas", "label": "poster"}
{"text": "expert authors of the DINI Certificate 2022 DINI e. V. Support improvement of information and communication services and further development of information infrastructures: At higher education and research institutions, On regional and national level. For Repository Operators / Hosts: Get orientation about best practices in the repository landscape; Ensure that you remain interoperable (metadata schemes, interfaces, technical side ...); Gain trust for your repository (the DINI Certificate stands for quality and trustworthiness / reliability). 32 Outreach License information (logos excluded): Creative Commons Attribution 4.0 International, https://creativecommons.org/licenses/by/4.0/deed.de On behalf of the DINI working group of Electronic Publishing: Pascal-Nicolas Becker, The Library Code, https://orcid.org/0000-0003-2169-1261 Daniel Beucke, G\u00f6ttingen State and University Library, https://orcid.org/0000-0003-4905-1936 Isabella Meinecke, Hamburg State and University Library, https://orcid.org/0000-0001-8337-3619 Marcel Meistring, Helmholtz Open Science Office, https://orcid.org/0000-0001-6347-9926 Jochen Schirrwagen, RWTH Aachen University, https://orcid.org/0000-0002-0458-1004 This poster is an updated version based on: Vierkant et al. (2019). Trust me, I\u2018m a repository manager. Open-Access-Tage 2019 (OAT19), Hannover, Deutschland, https://doi.org/10.5281/zenodo.3449041. The Certificate The DINI Certificate of Open Access Publication Services 2022 pursues the following goals: Improving the publication infrastructure for electronic publishing; I. Strengthen Open Access based forms of publishing; II. Integration into national and international research infrastructures. III. 103 Submissions since 2004 7 The DINI Certificate Is frequently referenced in working papers of international infrastructure projects and initiatives for repositories and Diamond Open Access, such as DIAMAS, COAR, OpenAIRE; Is presented and discussed with the repository community at national and international conferences (e.g. Open Access Days Germany, PUBMET); Has taken steps towards internationalization (adaption to the requirements of Austrian publication services); Is recommended by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) for publication in trustworthy repositories; On-going development of the certificate also in the context of projects of the WG members (e.g. PID Network, openCost, CRAFT-OA); Is available in English and German. Who is DINI ? DINI (Deutsche Initiative f\u00fcr Netzwerkinformation / German Initiative for Network Information) founded in 2002; Member institutions such as research libraries, IT centers, media and service facilities; Organized in seven working groups. Aim and Mission No. of certificate versions since 2004 Publicize and recommend best practices; Foster the development of standards and their implementation; Register and advertise Competence Centers using modern web-based technologies; Improve interdisciplinary exchange through congresses, workshops, expert conferences, etc. Advertise funding programs and encourage new ones. Goals The present catalog of criteria translates these general expectations of scientific publishing into concrete minimum requirements of Open Access publication services. 71 Minimum requirements 53 Recommentations Within 11 certification aspects: Visibility of the services; Guidelines (policy); Support of authors and publishers; Legal aspects; Information security; Indexing and interfaces; Open metrics; Long-term archiving; OAI interface; OAI-PMH: additional requirements; Metadata requirements of the OAI interface. Revised by experts every three years. For Users: Deposit your resource in a reliable / trustworthy repository; Be sure your work will be permanently available; Be sure your work can be found in the best possible way / has optimal visibility (metadata, interfaces, indexing ...). For Institutions: Show the world your efforts and Commitment for the permanent operation of a ", "label": "poster"}
{"text": "TOI 4562 b young planets are key: HIP 67522 and TOI 4562 Alexis Heitzmann, Marsden S., Zhou G., Wright D., Petit P., Huang X. C., Quinn S. Observations are mandatory for validating models explaining the formation & evolution of planetary systems Specifically, we need to map planet characteristics (mass, radius, orbital eccentricity, spin-orbit alignment...) as a function of time It is of utmost importance to focus on young (between disk dissipation and a few 100 Myr) systems because: It is where most of the changes happen (atmospheric evaporation, planet migration...) This primordial population is lacking in the current sample But young stars are very challenging to find and planet characterisation is greatly hindered by stellar activity We built from scratch a model to recover the obliquity, accounting for stellar surface spots The orbital plane of HIP 67522 b is aligned with its star's spin-axis HIP 67522 b is the youngest Jupiter sized planet with precisely measured obliquity HIP 67522 b is a significant addition to the planet obliquity distribution, where planets below ~100 Myr all seem to be well-aligned! Scan the QR code Age: 17 Myr Period: 6.96 days Radius: 0.93 (10 ) Mass: Unknown Obliquity: 6 \u00b1 6 degrees HIP 67522 Age: 300 \u00b1 190 Myr Period: 225.1 days Radius: 1.15 Mass: 2.3 Eccentricity: 0.77 1 Myr 10 Myr 100 Myr 1 Gyr 10 Gyr Second longest period planet in the TESS sample 2 years of RV follow-up yielded precise mass and eccentricity One of the most eccentric young planets (see poster background) Why is this TOI 4562 b so eccentric? Well, one (out of 4) transit is late by ~25 min, a strong indication of a perturbing companion! Probably not on its path to becoming a Hot Jupiter, unless eccentricity oscillations can trigger tidal circularization. 1.0 0.9 0.8 0.7 0.6 0.5 0.4 0.3 1.0 0.1 0.01 0.3 0.5 0.8 0.03 0.05 0.08 0 50 150 100 10 100 1 000 10 000 TOI 4562 \u2295 R (Heitzmann et al. 2021) (Heitzmann et al. to be submitted) alexis.heitzmann@usq.edu.au Jup R Jup M Jup R b b Semi major axis (AU) Eccentricity Age (Myr) Obliquity (degrees) By following up 2 young planets found by TESS (HIP 67522 b and TOI 4562 b), we meaningfully contribute to the young planet sample! My ADS & > 6 (Jupiter sized) < 6 (Neptune sized) \u2295 R \u2295 R HIP 67522 b (If you like this plot, go check out poster 102.174 by J. Dong) b b", "label": "poster"}
{"text": "ChatBot Duel: AI vs. Online Surveys ONLINE SURVEYS: YOUR INPUT, THEIR SILENCE Online surveys aim to collect information from participants who respond to the link through internet-based communicatio n technologies ( i.e., platforms and email). Structure Including open-ended and close-ended questions (i.e., yes/no questions, multiple choice, scaled questions) based on the purpos e of the survey. predominance In the 1990s, the emergence and proliferation of online surveys replaced the predominance of traditional surveys owing to thei r strengths relative to cost and speed. 89% of clients and suppliers use online surveys on a regular basis to gain insights from customers. Advantages Reduces data collection time and costs by being available 24/7 for respondents to access and complete. Be safer and more confidential for respondents when being asked about sensitive questions or discussing sensitive topics. Disadvantages Lack of engagement, questionnaire design without interactivity, surve y fatigue , complexity , inconvenience , a nd respondents\u2019 lack of diligence. Chatbots: Get Your Survey BACK! Statistics Surveys Compared to online surveys, chatbots can generate higher response rates and higher quality information in the aspect of ite m differentiation and missing questions. By using such natural and conversational interfaces for chatbot-led survey design, participants may feel more comfortable an d interested in proactively interacting with this survey tool. This humanlike conversation between chatbots and respondents in the process of survey completion can trigger a high level of self -disclosure because they treat chatbots as interaction partners. Beyond Human: Chatbots Crafting the Future of Surveys This research incorporates the notion of media richness theory that the degree of information dissemination is capable o f enhancin g th e degre e o f a receiver\u2019 s understanding , providi ng theoretic al suppo rt f or t he equivale nt potenti al of chatbo ts to online tools in conducting surveys for market research. Contribute to the existing literature on AI conversational marketing. 1 Contributions Provide guidance for marketing practitioners about the strategic use of chatbots in surveys to obtain insightful information and data from respondents. 2 Presenter: Liz Yingxue Zhao (UABS Marketing PhD Candidate)", "label": "poster"}
{"text": "We reviewed the LO scheme in the current and the on-going upgraded receiver bands in ALMA system. Except Band-1, the fundamental frequency of the existing local oscillators in the ALMA receivers ranges from 12.4 to 25.8 GHz followed by various type of frequency multiplier. The frequency of these signals will overlap the new IF frequency range in the ALMA WSU (4- 16, 4-20 GHz etc.). Therefore, spurious signal may enter in the new IF range due to the leakage. To investigate the phenomena, leakage power level at the IF output and the power ratio of the harmonics after frequency multiplication are measured in a W-band system. As expected, the \u201cleakage\u201d power level is proportional to the relative power ratio of the 5th/7th harmonic to 6th signal. It is thus recommended to choose the LO starting frequency as high as possible (> highest IF frequency + baseband bandwidth). Impact of LO Leakage in the New IF Frequency Range of the ALMA Wideband Sensitivity Upgrade Chau-Ching Chiong, Chen Chien, Teddy Huang, Yuh-Jing Hwang Institute of Astronomy and Astrophysics, Academia Sinica, Taiwan LO Leakage in ALMA System Except Band-1, ALMA LO signal is generated by frequency multiplication from low frequency YTO (YIG-tuned oscillator) at ~ 12 to 18 GHz via various schemes. It starts from 12 GHz to avoid overlap with the IF frequency range. However, for some observation, as in the case of Band-6, when the LO starting frequency is close to the IF, as reported in Spurious Responses from IF Signals above 12 GHz (Napier 2010), LO2 will still down-converts significant LO \u201cleakage\u201d signal to the IF output because the roll-off response in the IF spectrum is not sharp enough. LO2 mixes LO signal at USB with sky signal at LSB (Napier 2010) Band-6 LO \u201cleakage\u201d at IF output (Napier 2010, in AIV-2057) Origin of the \u201cLeakage\u201d Signal However, the frequency multiplier is not ideal. At the output of the multiplier, not only the signal at the desired frequency (x6 or x3) but also the unwanted harmonics are generated. Band 6 LO scheme (From Saini et al. 2021). Filters are placed after frequency multipliers to suppress unwanted harmonics . Start freq. 13 GHz Output after x6 (GHz) Output after x3 (GHz) x1 x2 x3 13, 26, 39 x2 x3 x4 x5 x6 x4 52 104 156 208 260 312 x5 65 130 195 260 325 390 x6 78 156 234 312 390 468 x7 91 182 273 364 455 546 x8 104 208 312 416 520 624 x9 117 234 351 468 585 702 x10 130 260 390 520 650 780 These harmonics will also reach the mixer with various power levels. The \u201cleakage\u201d signal will be generated by mixer via mixing nearby harmonics. In this Band-6 x18 scheme, x1 signal can be generated by (x14-x15-x16), (x20-x21) etc. Bandpass filter YTO GHz 13 x7 GHz 91 x6 78 x5 65 x8 104 \u2026 WR10 cutoff 52 x4 GHz x18 234 x20 260 \u2026 WR3.4 cutoff 208 x16 \u2026 195 x15 182 x14 156 x12 \u2026 x6 x3 x21 273 Harmonics in Band 6 LO generation. Numbers with strikethrough represent cutoff by waveguide (WR-10 and WR4.3). The mixer output spectrum is dominated by the LO leakages. We found a close relation between the leakage signal power and the 7th / 6th power ratio, which is thought to be the dominant scheme to generate 1st signal at IF output (left figure). Besides fundamental tone, other harmonics (x2, x3\u2026) can also be found at the mixer IF output port (right figure). (x2, x3, x4) signal shows different slopes when plotting with the x6/(x7, x8, x9) suppression ratio, respectively. This implies multiple mixing schemes other than x6 are involved. Proposed Band 4+5 LO Scheme The starting frequency of the Band 4+5 in LO chain is 24-32 GHz (> IFhigh (18 or 20 GHz in WSU) + baseband bandwidth). The harmonic suppression in the frequency multiplier has to be strictly controlled. Bandpass filter does help, but cannot suppress all harmonics due to wide tuning range in WSU. Balanced frequency multiplier is the solution for achieving high harmonic suppression. Verification by x6 W-band Frequency Multiplier A commercial x6 W-band frequency multiplier by OML (S10MS-AG) is used to in", "label": "poster"}
{"text": "AI Ethics \u2022 Recommended preparation included RS co-lead\u2019s top recommended readings, podcasts, and films. \u2022 Topics: Environment, dis/misinformation, labor (invisibilized and/or displaced), bias, privacy Agenda Jamboard AI, Art, and Copyright \u2022 Lowest attendance, but we had a good discussion on fair use, copyright, and copyright infringement. Agenda Jamboard Campus Activities During the first half of 2023, many groups on campus were addressing ChatGPT and AI/ML (more generally) in different ways. The campus has an active AI/ML and data science research community on one hand, while many disciplines which have academic writing assignments were grappling with ChatGPT. In October 2023, the library started receiving requests to participate in AI literacy and teaching activities discussions which more widely support the campus Overview What are librarians to do when widely and publicly accessible chatbots burst onto the academic scene with promises of easy no-work essays (but produce sophomoric writing), a research assistant that will destroy libraries (but can\u2019t quote citations), and the end of tedious repetitive tasks (but really have been used to try to replace artists and other creative work)? Start a discussion group. Of course. This is a \u201chow we did it\u201d poster. The Co-Leads Kat is in the Library\u2019s Research Services (RS) Department. She has a science background, and earned a MS in Data Science in 2017, although involvement in data science realm was keeping track of conversations on AI/ML ethics and bias issues to help inform consultations and interactions with campus researchers and the RDM community. Carrie is in the Library\u2019s Teaching and Learning (T&L) Department. Her focus is info lit instruction and student engagement. Carrie has a Humanities background with an MS in Art History. She has zero background in computer science or AI. She represents the newcomer perspective with an eye to making AI accessible to others who share her background and perspective. ChatGPT the Early Days Internal Library Discussion Group While RS co-lead tested ChatGPT bias in December 2022, the significance related to instruction started with a comment from a University Writing Program (UWP) instructor late December: \u201c[This essay assignment submission was so weird. They didn\u2019t even correctly identify the characters in the book.]\u201d This resulted in early conversations with UWP instructors on LLMs, extensive testing of ChatGPT, and librarian contributions to \u201cThe Challenges of ChatGPT in a Composition Classroom\u201d an internal document shared with writing program lecturers Feb 2023. Separately, T&L started internal discussions on ChatGPT in Jan 2023: \u2022 Addressing faculty concerns around cheating and plagiarism. \u2022 Whose responsibility it was to support faculty in navigating AI. \u2022 Looking at what was being done on other campuses/libraries. In preparation for the discussion group, the co-leads had planning discussions to identify our goals, the format, possible topics. Overall, we wanted a place to have shared learning and a discussion on how AI/ML is impacting academic libraries, and higher education in general. QR codes link to our suggested preparation, discussion questions, slide decks, jamboards, and feedback, where appropriate. Call for Participation \u2022 Initial discussion was well attended with staff from most departments in the library. Covered goals, logistics, and general concerns. \u2022 Plus/Delta feedback was very positive. Agenda Jamboard Chatbots + ChatGPT \u2022 Presentation on chatbots + open discussion \u2022 Brief history of Chatbots and NLM \u2022 How LLMs function in layperson\u2019s terms \u2022 Monetization, bias, and ethics Slide deck AI in Instruction \u2022 Included resources to prepare for discussion \u2022 Incorporating AI Literacy in instruction \u2022 ChatGPT session transcript review Agenda Jamboard Campus Action: Generative AI Guidelines \u2022 Focuses on data security and privacy. While UCR data is secure under Google Cloud Platform agreement, it isn\u2019t always clear which Google", "label": "poster"}
{"text": "THE ROLE OF THE LIMK1 GENE ON SHORT-TERM MEMORY FORMATION IN DROSOPHILA MELANOGASTER Zalomaeva E.S.1,2, Falina V.S.2, Nikitina E.A.1,2, Zhuravlev A.V.1, Savvateeva\u2010Popova E.V.1 1Pavlov Institute of Physiology Russian academy of sciences 2The Herzen State Pedagogical University of Russia Nowadays one of the topical problem of neuro\u2010 biology is the research of the etiology and progres\u2010 sion of different neurodegenerative diseases. One of the causes of neurodegenerative diseases is dis\u2010 turbance of actin remodeling cascade whose key enzyme is LIMK1. Drosophila constitutes a conven\u2010 ient model for studying the link between genome organization and chromosome architecture ob\u2010 served in cognitive disorders. The revealed associa\u2010 tion between limk1 gene's mutational damage, changes in its expression and activity as well as cog\u2010 nitive impairment allows to use current model for the study of neurodegenerative and genomic dis\u2010 eases. INTRODUCTION Drosophila melanogaster\u2014the most convenient model object \u2666Molecular\u2010genetic studies of the human genome have emphasized the evolutionary conservation of homologous genes from different organisms. \u2666limk1 gene D. melanogaster has 71% homology with the limk1 gene H. sapiens \u2666Drosophila is especially advantageous for testing gene interactions and allows the usage of several mutant or transgenic models at a time. \u2666Drosophila mutations in such genes help to under\u2010 stand the putative function of a newly isolated hu\u2010 man disease gene. \u2666D. melanogaster have short life span (Figure 1) \u2666Low maintenance costs \u2666No legislative limitations brought about by \u201canimal defending laws\u201d The main purpose: to analyze the formation and dynamics of short\u2010term memory in D. melanogaster stocks with limk1 gene polymorphism: Canton\u2010S, Berlin and Oregon\u2010R Figure 3. Individual courtship elements Figure 1. Drosophila life cycle Canton\u2010S stock has a single\u2010nucleotide polymorphism C/T (+12 bp) in the binding site of the M1 transcription factor. Berlin stock characterized by disturbances in primer binding in intron 2 and near introns 3 and 4. Also this stock has single\u2010 nucleotide polymorphisms in the N\u2010terminal part of the gene (including the M1 binding site and the 1st part of intron 1), some of which correspond to Canton\u2010S stock polymorphisms. Oregon\u2010R stock hasn\u2019t fragment between primers are limited the region with both LIM\u2010domains and part of the PDZ\u2010domain. Also this stock has multiple polymorphisms in the 1st intron: \u2666 A/T\u2010rich insert 28 bp; \u2666 deletions of 8 bp and 9 bp \u2666 Change the CAA/AG\u0421 Conditioned courtship suppression paradigm was used to asses learning ability and short\u2010term memory formation. 1. A 5\u2010day\u2010old virgin male was put in a special box with a fertil\u2010 ized female Canton\u2010S and was left for 30 minutes (Figure 2). 2. Courtship behavior was analyzed in naive males and in males in 0, 15, 30 and 60 minutes after training to assess the forma\u2010 tion and dynamics of short\u2010term memory. The behavior of the male was recorded in a special program for 300 seconds. We re\u2010 corded the start time of individual courtship elements (Figure 3) and the execution time of non\u2010courtship elements (activity, prining, rest). 3. We calculated the learning index (LI) to assess the effective\u2010 ness of training. Randomization test was used to statistical analysis. Figure 2. Special box for training and testing RESULTS Thus, Canton\u2010S and Berlin stocks capable of formation short\u2010term memory and to preserve it, while Oregon\u2010R incapable of learning and formation short\u2010term memory. Polymorphisms in the limk1 gene apparently contribute to changes in the content and ratio of LIMK1 isoforms in the analyzed stocks, that influence in processes of learning and formation short\u2010term memory. Figure 4. Learning index (LI) Canton\u2010S, Berlin and Oregon\u2010R stocks * LI significantly differents from zero, p<0,05 \u25b2 LI significantly differents from Canton\u2010S \u25a0 LI significantly differents from Berlin MATERIALS AND METHODS 0 10 20 30 40 50 60 70 80 90 100 0 min 15 min 3", "label": "poster"}
{"text": "Visibiliser et ouvrir ses publications \uf8ffSNSF OA Check : d\u00e9couvrir son taux d\u2019OA et comment l\u2019am\u00e9liorer \uf8ffArchive ouverte UNIGE : partager ses publications, sous forme de manuscrit accept\u00e9 si la version publi\u00e9e ne peut \u00eatre diffus\u00e9e Trouver des contenus en Open Access Obtenir la prise en charge des \u00e9ventuels frais V\u00e9rifier la compatibilit\u00e9 OA de ses revues pr\u00e9f\u00e9r\u00e9es Le couteau suisse de l\u2019OA Tous les outils \u00e0 port\u00e9e de main \uf8ffArchive ouverte UNIGE : pour les contenus UNIGE \uf8ffUnpaywall : plugin de navigateur web, cherchant dans toutes les archives ouvertes \uf8ffDOAB : r\u00e9pertoire de livres 100% Open Access \uf8ffDOAJ : r\u00e9pertoire de revues 100% Open Access 1. Passer par l\u2019outil de votre organisme de financement : ex. ChronosHub (articles FNS) ou mySNF (livres FNS) 2. Page accords UNIGE avec les \u00e9diteurs : v\u00e9rifier si un accord existe et suivre la proc\u00e9dure d\u00e9crite 3. Fonds d\u2019aide \u00e0 la publication UNIGE : demander un soutien financier si les conditions sont remplies \uf8ffSherpa Romeo : politiques des revues vis-\u00e0-vis de la voie verte \uf8ffDOAJ : r\u00e9pertoire de revues 100% Open Access \uf8ffCabells : liste des revues \u00e0 \u00e9viter, en raison de pratiques pr\u00e9datrices Outils sp\u00e9cifiques \u00e0 des financeurs : \uf8ffChronosHub (FNS) \uf8ffJournal Checker Tool (cOAlition S) BIBLIOTH\u00c8QUE openaccess@unige.ch Floriane Muller, pour la Biblioth\u00e8que de l\u2019UNIGE, 2023 Ce document est sous licence Creative Commons Attribution - Partage dans les m\u00eames conditions 4.0 International http://creativecommons.org/licenses/by-sa/4.0/deed.fr https://doi.org/10.5281/zenodo.10034324", "label": "poster"}
{"text": "A Machine Learning Inspired Method Reveals the Mass of K2-167 b Zoe L. de Beurs1,2, Andrew Vanderburg1,2, Christopher J. Shallue3, Joseph E. Rodriguez4, Sebastian Zieba5,10, Annelies Mortier6,7, Lars Buchhave8, Luca Malavolta9, HARPS-N Telescope Collaboration Discovering earth-mass exoplanets orbiting bright nearby stars requires precise radial velocity (RV) observations. Currently, we are limited by spurious RV signals introduced by the host star in the form of stellar activity (i.e. faculae, starspots). These stellar signals can mimic or hide exoplanet signals. Inspired by our successful implementation of a neural network stellar activity mitigation method on solar data (de Beurs et al. 2020), we designed a simplified machine learning (ML) method that can be applied to extrasolar stars. As a proof-of-concept, we tested this method on one star: K2-167. K2-167 was first found to host a transiting super-Earth by the K2 mission (Vanderburg et al. 2016b; Mayo et al. 2018). Recently, the planetary signal was re-detected by TESS (Ikwut-Ukwa et al. 2020). K2-167 is an ideal test case for our method. It is the brightest star observed by K2 that hosts a validated planet, and it is a relatively active, yet slowly rotating F7. HARPS-N began observing K2-167 in late 2015, but stellar activity has prevented a confident detection of the planet\u2019s RV signal, even with the aid of state-of-the-art methods like GP regression. Our strategy is to use a simplified ML method to identify and interpret the subtle changes to stellar spectra that are caused by stellar activity. Background Data K2 \u2013 K2-167 was observed during K2 Campaign 3 from 2014 November 17 to 2015 January 23. After extraction, the lightcurves were reprocessed by using the methods described in Vanderburg & Johnson (2014) and Vanderburg et al. (2016a). TESS \u2013 K2-167 was observed by Camera 1 during TESS Sector 2 from 2018 Aug22 to Sept 20. The lightcurves were generated using NASA\u2019s SPOC pipeline. HARPS-N \u2013 HARPS-N is a vacuum-enclosed cross-dispersed echelle spectrograph designed to achieve high-precision RVs (Cosentino et al. 2012). We collected 76 precise RV observations of K2-167 between Aug 2015 and Oct 2016. CCF Input Representation \u2013 For our ML model, we have to pre- process our data products into a uniform format such that the model becomes sensitive to shape changes due to stellar activity, not translational shifts caused by Keplerian shifts. We describe this input representation in detail in de Beurs et al. 2020. Results o We find that our simplified approach to stellar activity corrections yields a significant improvement in both the RV scatter (by a factor of ~ 2) and the precision with which we recover the mass of the transiting planet (improving a 2.3\u03c3 significance detection into a 4.0\u03c3 significance detection; Figure 3). Our MCMC fit found that the mass of 6.12!\".$% &\".%\" \ud835\udc40', the orbital period and phase of the detection agrees with the known 9.97857 day period from transit observations Future Directions o In the future, these or similar techniques could be widely applied to solar-type (FGK) stars, help measure masses of planets from TESS to fulfill the level 1 science requirement, and eventually help detect habitable-zone Earth-mass exoplanets. o We plan to further validate our method with HARPS-N Rocky Planet Targets and young planets orbiting young active stars Acknowledgments We thank the Office of Undergraduate Research, TIDES Advanced Research Fellowship, Dean\u2019s Scholars, and the Junior Fellows Honors Program for their generous support. References Dumusque et al. 2014; de Beurs et al. 2020; Haywood PhD Thesis 2015; Vanderburg & Johnson 2014; Vanderburg et al. 2016a. Vanderburg et al. 2016b; Mayo et al. 2018; Shallue & Vanderburg, AJ 155, 94, 2018; Cosentino et al. 2012; Ikwut-Ukwa et al. 2020; Akeson et al. 2013 zdebeurs@mit.edu Figure 4: Periodogram: HARPS-N Raw (a) and Corrected (b) RVs in Fourier space. The peaks in the top panel that correspond to stellar activ", "label": "poster"}
{"text": "Young migrants from North Africa. What do we know? A scoping review to explore their health status and access to health services. Eva P. Rocillo Arechaga1,2, Barbara Broers1,3, Catherine Chamay Weber4, Lloyd Orph\u00e9e Rigumye1, Melanie Pinon1,5, Yves-Laurent Jackson1,3 1) Division of Primary Care Medicine, Geneva University Hospitals (HUG), Geneva, Switzerland; 2) Institute of Global Health, Faculty of Medicine, University of Geneva (UNIGE), Geneva, Switzerland; 3) Department of Community Health and Medicine, Faculty of Medicine, University of Geneva (UNIGE), Geneva, Switzerland; 4) Adolescent Health Unit, Division of General Paediatrics, Department of Women, Child and Adolescent, Geneva University Hospitals (HUG), Geneva, Switzerland; 5) University of Applied Sciences and Arts Western Switzerland, School of Health Sciences (HES-SO), Geneva, Switzerland. In the last decades, adolescents and young adult migrants from North Africa (NA) arrived in Europe in large numbers1. Field observations reported features not previously described in other similar groups including high mobility across borders, precarious living conditions, use of psychotropic substances and high-risk behaviours such as prostitution and illegal activities2,3. Existing health literature on this population seems to be limited and fragmented. INTRODUCTION To better understand NA adolescents and young adult migrants\u2019 health status, access and use of healthcare. LANGUAGE \u2022 English, French, Spanish CONTEXT \u2022 Studies conducted in European region (WHO) CONCEPT \u2022 Health status \u2022 Health services \u2022 Accessibility to health services \u2022 Use of health services POPULATION \u2022 Migrants from NA countries \u2022 First generation migrant \u2022 Any legal condition \u2022 From 10 to 24 years old \u2022 Any gender STUDIES \u2022 Peer-reviewed articles \u2022 Non-indexed reports \u2022 From 1990 to 2022 INCLUSION CRITERIA References 1United Nations Department of Economic and Social Affairs, Population Division, \u201dInternational Migrant Stock 2020,\u201d United Nations (UN). Department of Economic and Social Affairs (DESA), 2020. 2Trajectoires, \u201dRecherche-action sur la situation des mineurs non accompagnes marocains,\u201d Trajectoires, Squats et Bidonvilles, 2018 3G. Pfau, G. Flye-Sainte-Marie och C. Pequart, Tendances recentes et nouvelles drogues, Paris: Observatoire Francais des Drogues et des Toxicomanies, 2019 4H. Arksey och L. O\u00b4Malley, \u201dScoping studies: towards a methodological framework,\u201d International Journal of Social Research Methodology, vol. 8, nr 1, pp. 19-32, 2005. 5The Joanna Briggs Institute, \u201dJoanna Briggs Institute reviewers\u00b4 manual: 2015 edition / supplement,\u201d The Joanna Brigs Institute, 2015. STUDIES Most studies (n=9) were published between 2015 and 2021. All studies were observational, 9 were cross-sectional and 3 were case reports. Seven studies included NA migrants only. POPULATION The overall number of persons included was 1374, most of them being from Morocco (1150). Nine studies included only males and 11 focused on unaccompanied minors. For most studies (n=10) age range varied between 12 and 18 years old CONCEPT Five studies explore aspects related to general health, with dental caries, iron deficiency and dermatological issues reported as the most prevalent disorders. Six studies provide information on infectious diseases. Mental health and substance use was also explored in 5 studies, benzodiazepines and cannabis being the most often reported substances. Only 3 studies covered service provision all emphasizing the importance of transcultural approach. CONTEXT Studies were conducted in Spain (n=7), France (n=4) and Germany (n=2). Acknowledgement CONCLUSIONS DISCUSSION RESULTS Did you ever work with such migrants? We are looking for experts. Please get in touch with us at Eva.RocilloArechaga@hug.ch METHODS We conducted a scoping review following Arksey and O\u00b4Malley process and recommendations by Joanna Briggs Institute and based on the Population-Concept- Context (PCC) framework4,5. We searched the followin", "label": "poster"}
{"text": "Authors: Karun Gaur, Kinjal Dawda, Silke Oeschger-Delautre The intersection of health and sustainability \u2013 an Indian pharma perspective Introduction Climate change is a public health emergency, impacting the world\u2019s most vulnerable populations due to global health inequities. The World Health Organization estimates that nearly 14 million people die each year from environmental health risks. The pharmaceutical industry plays a vital role in providing good health for people, yet also impacts the planet's health. According to the World Economic Forum, healthcare is responsible for 4.4% of global emissions, more per dollar of revenue than the automotive sector, and its CO2 footprint will triple by 2050 if left unchecked. Here we look at a case study of one of the largest Indian pharma companies to make medicines more sustainable from manufacturing to the journey it takes to the patient. Methodology The methodology assesses the environmental, social, and governance risks associated with the company\u2019s operations and supply chain, including the impact of the company\u2019s products and services for its patients, and its activities on the environment, such as biodiversity, carbon emissions, waste generation, and water usage. Results and Discussions Dr. Reddy\u2019s Laboratories has always focused on science and sustainable business practices, making significant progress on its ESG agenda - setting goals on reaching 1.5 billion patients by 2030, innovating to improve the standard of treatment with three new solutions each year, and becoming carbon-neutral by 2030. This is reflected in several initiatives to enable equitable access to patients in low- and middle-income countries (see pie chart below), strengthen health systems, and ensure digital health inclusion. The company turned water-positive in 2023, using renewable energy, energy-efficient technologies, and sustainable transportation (air-to-sea shipments) to lower its carbon emissions (see graphic below, which shows the progress in one year). Dr. Reddy\u2019s has also implemented a sustainable API manufacturing and development process focused on reducing waste, conserving water, and minimizing the use of hazardous chemicals. The impact of the direct operations of a company can be significant. However, there are also limitations. For example, sourcing adequately recyclable primary packaging is still challenging, as it directly impacts patient safety. Companies must also address the environmental impact across their entire value chain, build public-private partner- ships, and work with partners and peers to strengthen health systems. The pharma industry can\u2019t address these factors alone; all health stakeholders must collaborate to find patient-centric solutions supported by sustainable policies and legislation. Conclusion The example shows that the global pharma industry has made progress in continuously enhancing sustainability in its operations. ESG assessments can help standardize efforts, identify areas of improvement, and align with stakeholder expectations on risk management and long-term sustainability. On the other hand, providing safe and high-quality medicines for patients will always come with the challenge of finding a balance, and the responsible use and disposal of medicines plays a vital role in minimizing their impact. Partnerships across the value chain and the collaboration of health stakeholders can help find patient-centric solutions while making ESG an integral part of business. www.drreddys.com, Dr. Reddy\u2019s Laboratories SA, Elisabethenanlage 11, 4051 Basel, Switzerland Contact: karung@drreddys.com, silkeo@drreddys.com PATIENTS REACHED (IN MILLIONS) Low-and-middle income countries Rural India Others 534\u2019418 1\u2019149\u2019510 3\u2019960\u2019586 2\u2019890\u2019503 FY 2021-2022 FY 2022-2023 ENERGY CONSUMPTION (IN GIGAJOULES) Renewable sources Non renewable sources 302\u2019466 214\u2019257 166\u2019247 137\u2019627 FY 2021-2022 FY 2022-2023 GREENHOUSE GAS EMISSIONS (METRIC TONNES OF CO2 EQUIVALENT) Scope 1 Scope 2 Integrat", "label": "poster"}
{"text": "Very recently, a spectroscopic determination of the Boltzmann constant, kB, has been performed at the Second University of Naples by means of a rather sophisticated implementation of Doppler Broadening Thermometry (DBT) [1]. Performed on a 18O-enriched water sample, at a wavelength of 1.39 \u03bcm, the experiment has provided a value for kB with a combined uncertainty of 24 parts over 106, which is the best result obtained so far, by using an optical method. In the spectral analysis procedure, the partially correlated speed-dependent hard-collision (pC-SDHC) model was adopted. The uncertainty budget has clearly revealed that the major contributions come from the statistical uncertainty (type A) and from the uncertainty associated to the line-shape model (type B) [2]. In the present work, we present the first results of a theoretical and numerical work aimed at reducing these uncertainty components. It is well known that molecular line shapes exhibit clear deviations from the time honoured Voigt profile. Even in the case of a well isolated spectral line, under the influence of binary collisions, in the Doppler regime, the shape can be quite complicated by the joint occurrence of velocity-change collisions and speed-dependent effects. The partially correlated speed-dependent Keilson-Storer profile (pC-SDKS) has been recently proposed as a very realistic model, capable of reproducing very accurately the absorption spectra for self-colliding water molecules, in the near infrared [3]. Unfortunately, the model is so complex that it cannot be implemented into a fitting routine for the analysis of experimental spectra. Therefore, we have developed a MATLAB code to simulate a variety of H2 18O spectra in thermodynamic conditions identical to the one of our DBT experiment, using the pC-SDKS model. The numerical calculations to determine such a profile have a very large computational cost, resulting from a very sophisticated iterative procedure. Hence, the numerically simulated spectra (with the addition of random noise) have been used to test the validity of simplified line shape models, such as the speed-dependent Galatry (SDG) profile and pC-SDHC model. In particular, we have used the global fitting procedure that is described in Ref.[4]. Such a procedure is very effective in reducing the uncertainty resulting from statistical correlation among free parameters. Therefore, the analysis of large amounts of simulated spectra has allowed us to study the influence of the choice of the model and quantify the achievable precision and accuracy levels, at the present value of the signal-to-noise ratio. -1500 -1000 -500 0 500 1000 1500 0.2 0.4 0.6 0.8 1.0 Transmitted signal (V) Frequency detuning (MHz) P (Torr) 0.50 0.75 1.00 1.25 1.50 1.75 2.00 2.50 3.00 3.50 Useful References [1] L. Moretti, A. Castrillo, E. Fasci, M.D. De Vizia, G. Casa, G. Galzerano, A. Merlone, P. Laporta, and L. Gianfrani, Phys. Rev. Lett. 111, 060803 (2013) [2] A. Castrillo, L. Moretti, E. Fasci, M. D. De Vizia, G. Casa, and L. Gianfrani, J. Mol. Spectrosc. 300, 131 (2014); [3] N. H. Ngo, H. Tran and R. R. Gamache, J. Chemical Physics 136, 154310 (2012); [4] P. Amodio, L. Moretti, A. Castrillo and L. Gianfrani, J. Chemical Physics 140, 044310 (2014). [5] N. H. Ngo, H. Tran, and R. R. Gamache, J. Chemical Physics 136, 154310 (2012) Limits Hard collision model (Nelkin-Ghatak profile) ) v( f ') v v( A \u03b1 MB KS \uf072 \uf072 \uf072 \uf03d \uf0ac \uf0de \uf03d0 Soft collision model (Galatry profile) ') v,v \u03b4( ') v v( A \u03b1 KS \uf072 \uf072 \uf072 \uf072 \uf03d \uf0ac \uf0de \uf03d1 \uf0f7\uf0f7 \uf0f8 \uf0f6 \uf0e7\uf0e7 \uf0e8 \uf0e6 \uf02d \uf02d \uf0b4 \uf02d \uf03d \uf0ac \uf02d 2 2 3 2 1 1 \u03b1 'v \u03b1 v f ) \u03b1 ( ') v v( A MB / KS \uf072 \uf072 \uf072 \uf072 1 0 \uf0a3 \uf0a3\uf061 The multispectrum fitting procedure has been expressly designed and developed to analyze simultaneously a number of absorption spectra across a given pressure range, under the MATLAB environment, by means of a non-linear least-squares method. All the simulated spectra were fitted to the function here below: \uf028\uf029 \uf028 \uf029 \uf028 \uf029 \uf05b \uf05d \uf07b \uf07d 0 1 0 \u03c9 \u03c9 I A exp \u03c9 a a \u03c9 P \uf02d \uf0c2 \uf02d \uf02b \uf03d \uf028 \uf029 \uf028 \uf029 \uf0e5 \uf03d \uf03d M 1 j j j j ", "label": "poster"}
{"text": "Impact of spatial scale in cortical thickness networks is not significant in discriminating Alzheimer\u2019s and Autism from controls *Pradeep Reddy Raamana1, Stephen C. Strother1,3 and for the Alzheimer\u2019s Disease Neuroimaging Initiative 1 Rotman Research Institute, Baycrest Health Sciences; 3Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. *Corresponding author: praamana@research.baycrest.org 1 Introduction \u2022Development of automatic imaging biomarkers predictive of future cognitive decline is necessary for the early detection of neurodegenerative disorders such as Alzheimer\u2019s disease (AD). \u2022There has been great progress in the past few decades in this direction due to the advent of large multi-site datasets like ADNI that are publicly available. \u2022However, owing to the nature of large variability in disease presentation and overlap among different diseases in the early stages, the specificity and sensitivity of the imaging biomarkers is still unsatisfactory. \u2022In order to improve the accuracy of the base imaging biomarkers, network-level feature extraction is gaining popularity as the method of choice [1]. \u2022Here, we present \u2022one such approach whose potential has been demonstrated in ADNI dataset in discriminating AD from Healthy Controls (CN) [2], and \u2022a detailed study of its methodology to evaluate its robustness and understand the impact of the key choices [3] under 2 levels of separability. \u2022Results from replication analysis on a subset of Autism Brain Imaging Data Exchange (ABIDE) dataset. 2 Method and Results \u2022Given high potential for the development of accurate early detection methods and its wide-accessibility structural, T1 MRIs, thickness-based networks deserve a systematic study to understand \u2022the impact of the choice of edge metric that defines connectivity (such as correlation [4], similarity [2], dissimilarity [5]) \u2022the impact of the choice of cortical parcellation (patch-wise delineation vs region-growing vs functional ROI segregation) and its scale (size and number of ROIs) affect the network properties and their predictive performance? See Fig. 1. \u2022We perform this study using the data from ADNI and ABIDE datasets (demographics in Tables 1 and 2) under 3 levels of separability. \u2022Due to the variable sizes of ROIs, as shown in Fig. 2, approaches [2,4,5] rely on summary statistics to compute edge weights and do not utilize the rich description of thickness features. \u2022By discretizing the thickness distribution in each patch, we enable a histogram- based framework to compute edge weights from the entire distribution from a given patch, instead of basing them on summary statistics such as mean or meadians. \u2022We present and study 6 different methods of edge computation based on histogram distances as listed in Table 2, including two baseline methods. \u2022The predictive power of these 6 methods are studies at 6 different spatial scales (nodal sizes) of the cortical parcellation as noted in Table 2, using the cross-validation procedure published in [3,2]. \u2022The distributions of AUC for different combinations of edge definitions and scales are shown in Fig. 3. References: 1. Evans, A. C. (2013). Networks of anatomical covariance. NeuroImage, 80, 489\u2013504. 2. Raamana, P. R., Weiner, M. W., Wang, L., Beg, M. F. (2015). Neurobiology of Aging, 36 Suppl 1, S91\u2013S102. 3. Raamana, P. R., Strother, S. C., (2016). International Workshop on Pattern Recognition in Neuroimaging (PRNI), Trento, pp. 1-4. 4. He, Y., Chen, Z. J., & Evans, A. C. (2007), Cerebral Cortex, 17(10), 2407\u20132419. 5. Tijms, B. M., Seri\u00e8s, P., Willshaw, D. J., & Lawrie, S. M. (2012). Cerebral Cortex, 22(7), 1530\u20131541. Funding: This research has been sponsored by Canadian Institute of Health Research (CIHR), Ontario Brain Institute (OBI) and Ontario Neurodegenerative Disease Research Initiative (ONDRI). Type of base distribution Type of Edge Metric Acronym Definition Summarized Similarity (diff. in medians) MD exp(similarity) EMD raw distribution Wil", "label": "poster"}
{"text": "Structure of a Be binary Structure of a Be binary B-type, non-supergiant stars that have the highest rotation rates amongst non- degenerate objects. They are non-radial pulsators and undergo episodes of mass ejection which lead to the formation of a decretion disk around the star. The disk is viscous and very sismilar to accretion disks, except that it builds from inside out. Observationally, Be stars are known for their emission lines in Hydrogen (H\u03b1 in particular), linear polarisation, and IR excess. i n n e r B e d i s k spiral dominated disk bridge circumsecondary region circumsecondary region circumbinary region Tightly wound one armed structure Matter that escapes from behind the Be disk (away from the companion), meets up with the main arm Radio emission? A flow of matter is flung out of the system after it has been focused by the companion Characterized by: Observationally: Decretion and Accretion Decretion and Accretion in be star binary systems in be star binary systems Amanda C. Rubio, Alex C. Carciofi, J. E. Bjorkman Universidade de S\u00e3o Paulo; ESO Be stars Be stars Smoothed particle hydrodynamics (SPH) is a mathematical technique created to describe the dynamics of fluids in a discrete fashion, using particles. As Be disks are gaseous and dustless, mostly controlled by viscosity, SPH can describe them well. In our code, we have implemented particle splitting, which allows us to explore less dense regions of the disk [1, 2, 3]. Our goal is to characterise Be stars in binary systems. The presence of the companion tidally affects the Be disk in many ways, leading to profound changes in its structure. We ran a grid of SPH models for binary Be stars with different periods and different values for the viscosity of the disk, \u03b1. SPH simulations SPH simulations Inner disk Circular orbits of the particles Azimuthal symmetry Accumulation of matter in the inner disk Larger scale height (puffier disk) More emission in lines that are formed closer to the star, such as He Stronger V band magnitude This region is the closest to the central Be star, and the most oblivious to the presence of the companion, as it is dominated by the gravity field of the primary and strong viscous torque. Characterized by: But it is not the same as an isolated Be disk! Observationally, the consequences would be: The formation of Be stars is still not understood. How do they obtain their fast rotation rates? Currently, the most favoured scenario is that they are a product of binary star evolution: the future Be star gains mass and angular momentum from a donor star that evolves faster. The fact that many Be stars are found in systems with evolved objects (such as sub- dwarfs and neutron stars [4, 5]) is an indicator that this is a viable route. Why do we care about Why do we care about binary Be stars? binary Be stars? Fig. 1: Snapshot of one of our SPH simulations. The two back dots represent the Be star and the companion, while the colours represent the density of the gas around them. The 5 regions we could discern in our work are marked. Conclusion Conclusion spiral dominated disk Elliptic orbits of the particles Two armed density waves that travel through the disk Deviations from the VDD in velocities and scale height V/R variations in H\u03b1 The companion makes itself known by messing up the disk as it affects it tidally Characterized by: Observationally: Fig. 2: Snapshot of one of our SPH simulations. The back dot represent the Be star, while the colours represent the radial velocity of the gas around them. The density arms are the regions marked by the highest velocities. Fig. 3: Example of H\u03b1 profiles of a real Be binary (pi Aqr). The strength of the violet and red peaks (V/R) changes depending on the movement of the density waves in the disk. circumsecondary region Density depends strongly on viscosity and period Radial velocities have similar amplitudes, but azimuthal velocities are much larger for lower viscosities Part of the matter is accreted", "label": "poster"}
{"text": "UWS Research Festival 20th \u2013 24th June 2022 #UWSResearchMatters #UWSResearchFestival22 Examining the Communication Process of the Interpreters that Affects the Attitudes and Behaviours of Heritage Visitors", "label": "poster"}
{"text": "Pictures adapted from Biorender.com. PROJECT OUTLINE STABILITY AND DEGRADATION TESTS RECOVERY AND QUANTIFICATION OF SPIKED MNPs Fluorescent polystyrene (FPS) MNPs were recovered after digestion and filtration with Confocal Fluorescence Microscopy (CFM) and Scanning Electron Microscopy (SEM). No changes in morphology were observed. PLACENTAL TISSUE DIGESTION PROTOCOLS Spiked placental tissue was homogenized and enzymatically digested, followed by filtration over 700 nm glass fiber filters. Cleaner filter \uf0e0better digestion. This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under AURORA grant agreement No 964827. LEARN MORE AND FOLLOW OUR PROGRESS QUESTIONS? COMMENTS? AuroraResearch.eu/newsletter Learn more about AURORA, the team mem- Do you have questions about AURORA? bers, and our latest research progress. Visit Want to engage with us or inquire about our website, follow our social media channels, an opportunity to collaborate? Then send and subscribe to our newsletter: us an email or get in touch directly with a responsible team member! AuroraResearch.eu info@AuroraResearch.eu @AuroraProjectEU AuroraResearch.eu/about/team linkedin.com/company/AuroraResearch NEWS Sample Pre-processing Protocols for the (Spectro-)Microscopic Analysis of Micro- & Nanoplastics (MNPs) in Maternal and Fetal Tissues Laura M. Zoutendijk1, Laurens D. B. Mandemaker1, Zenzi Matla1, Lisa Zimmermann2, Lonneke van Dalen1, Bert M. Weckhuysen1, Florian Meirer1 1: Inorganic Chemistry and Catalysis, Debye Institute for Nanomaterials Science and Institute for Sustainable and Circular Chemistry, Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, The Netherlands 2: Food Packaging Forum, Staffelstrasse 10, CH-8045 Zurich, Switzerland Morphology Chemical composition Surface chemistry State of degradation Quantity Cultured spiked placenta cells \u2022 Optimize digestion \u2022 Ensure MNP stability Spiked placenta tissue \u2022 Optimize digestion and filtration \u2022 Find back MNPs \u2022 Determine recovery rate Non-spiked (environmental) placenta tissue \u2022 Detect MNPs \u2022 Determine MNP location \u2022 Analyze MNP degradation within body 200 nm FPS in water, 95 \u00b0C, 30 min. No agglomeration 200 nm FPS in 30% H2O2 No agglomeration 200 nm FPS in water, 95 \u00b0C, 2 hours Agglomeration occurs 200 nm FPS in pancreatin in TRIS-HCl No agglomeration Solution of badly digested tissue Homogenized placenta in buffer CFM image of 1 \u00b5m FPS (a) and SEM image of 200 nm FPS (b) recovered after digestion and filtration. CFM image of 0.5 \u03bcL droplet of 500 nm FPS in water (c) with color adjustments. Non-adjusted image is in right bottom corner. CONCLUSIONS AND OUTLOOK \uf0fcFluo-PS stable in used digestive agents. \uf0fcDigestion protocol made for placental tissue. \uf0fcFluo-PS in spiked digested tissue analyzed with CFM. \u2022 Calculate recovery rate of Fluo-PS in spiked digested tissue. \u2022 Adapt protocol to blood, amniotic fluid, urine, etc. \u2022 Towards analysis of non-spiked samples Placenta as received Solution of well digested tissue Glass fiber filter, well digested tissue Glass fiber filter, badly digested tissue Laura Zoutendijk l.m.zoutendijk@uu.nl 500 nm \u2022 To quantify the total number of recovered particles, the number of particles in a whole droplet can be counted. \u2022 Counting grids are used to stitch multiple microscopy images together. \u2022 The number of counted particles can then be compared to the number of particles theoretically present in the droplet: Recovery rate = Number of particles found back during analysis Theoretical number of spiked particles * 100% c b a", "label": "poster"}
{"text": "aPhyloGeo-Covid: A Web Interface for Reproducible Phylogeographic Analysis SARS-CoV-2 Variation using Neo4j and Snakemake Wanlin Li and Nadia Tahiri. Department of Computer Science, Universit\u00e9 de Sherbrooke, Canada ABSTRACT DATA INTEGRATION GitHub Link https://github.com/tahiri- lab/iPhyloGeo/tree/iPhylooGeo-neo4j Tahiri Lab website https://tahirinadia.github.io/ WORKFLOW Acknowledgements RESULTS CONCLUSIONS REFERENCES Brister, J. Rodney, et al. (2015). NCBI viral genomes resource. Nucleic acids research, 43.D1, D571- D577. Mathieu, E. et al. (2021). A global database of COVID-19 vaccinations. Nature human behaviour, 5.7: 947-953. O\u2018Toole, \u00c1. et al. (2021). Tracking the international spread of SARS-CoV-2 lineages B. 1.1. 7 and B. 1.351/501Y-V2 with grinch. Wellcome Open Research, 6 (2021). Tahiri (2012). Un nouvel algorithme pour retrouver les relations phylog\u00e9n\u00e9tiques entre la distribution g\u00e9ographique des esp\u00e8ces et leurs compositions g\u00e9n\u00e9tiques. \u00d8 This research developed an interactive analysis platform that facilitate efficient filtering and organization of input data for phylogeographical studies of SARS-CoV-2. \u00d8 The Neo4j database was integrated as a comprehensive repository, consolidating COVID-19 pandemic-related sequence information, climate data, and demographic data obtained from public databases. \u00d8 Additionally, the platform provides a scalable and reproducible phylogeographic workflow for investigating the intricate relationship between geographic features and the patterns of variation in diverse SARS-CoV-2 variants. \u00d8 Database currently contains 113,774 nodes and 194,381 relationships. \u00d8 The code is freely available to researchers and collaborators on GitHub. Neo4j Data Modeling facilitate \u2022 storage, \u2022 management \u2022 querying of extensive SARS-CoV-2 variants-related data. Neo4j Data Analytics ensure the repeatability and comparability of phylogeographic analysis results. \u00d8 The sliding window region with the lower RF distance was exclusively identified in the integrated analysis. \u00d8 Within the regions identified with lower RF distance, a special attention should be given to regions with positions between 792 to 940 residue. \u2022 The platform streamlines the extraction, validation, and integration of genetic and environmental data, overcoming the limitations of manual tools. \u2022 aPhyloGeo-Covid workflow utilizes a sliding window approach to identify region-specific subparts of viral genetic sequences affected by environmental conditions. \u2022 The application of Snakemake workflow management ensures that the phylogeografic analysis can be replicated, validated, and used as a reliable basis for further research or analysis. \u2022 The platform facilitates the sharing of research results, encourages collaboration and promotes the exploitation of previous work. \u00d8 Putative horizontal gene transfer (HGT) events were detected in the window regions spanning residues 792-940 of the amino acid sequences of 14 SARS-CoV-2 variants. Source Figure 1: Schema of Neo4j Database for Phylogeographic Analysis of SARS-CoV-2 Variation Figure 2: The networks of a single analysis experiment Figure 3: Integrated analysis of genetic data and environmental data Figure 4: Snakemake workflow of the algorithm based on the new pipeline aPhyloGeo Figure 5: Robinson and Foulds topological distance normalized changes over the alignment windows Figure 6: Putative horizontal gene transfer events found for the window regions of 792-940 residue (amino acid sequences) of 14 SARS-Cov-2 variants \u2022 Multiple sequences are aligned and segmented into numerous alignment windows \u2022 Robinson and Foulds (RF) metric was employed to quantify the dissimilarity between o the phylogenetic tree of each window and o the topological tree of geographic features. \u00d8 Tuning of window size and step size are required to optimize the analysis. \u00d8 Reproducibility played a critical role in this process. \u2022 The network highlights all entities serving as input data sources and their relationships. \u2022 ", "label": "poster"}
{"text": "CSSI Frameworks: Performance Engineering Scientific Applications with MVAPICH and TAU using Emerging Communication Primitives PI: Dhabaleswar K. (DK) Panda (OSU), Co-PIs: Sameer Shende (UO), Ahmad Abdelfattah (UTK), Yifeng Cui (SDSC) Institutions: The Ohio State University (OSU), University of Oregon (UO), University of Tennessee (UTK), San Diego Supercomputer Center (SDSC) 1. Load-aware designs for MPI asynchronous communication 2. Cross runtime coordination for MPI+X applications 3. Partitioned point-to-point primitives for efficient communication 4. Application-aware neighborhood collective communication 5. Support for adaptive persistent collective communication 6. Coordinated communication kernels on GPUs 7. On-the-fly compression for accelerating scientific applications Proposed Framework Proposed Innovations Motivation & Research Challenges NSF CSSI PI Meeting, Charlotte, NC, August 12-13, 2024 Award #: OAC-2311830 1. Designing and Optimizing GPU-aware Nonblocking MPI Neighborhood Collective Communication for PETSc, K. Khorassani, C. Chen, H. Subramoni, and DK Panda, 37th IEEE International Parallel & Distributed Processing Symposium (IPDPS '23), May 2023 2. Accelerating MPI AllReduce Communication with Efficient GPU-Based Compression Schemes on Modern GPU Clusters, Q. Zhou, B. Ramesh, A. Shafi, M. Abduljabbar, H. Subramoni, D. K. Panda, ISC High Performance (ISC '24), May 2024 3. MPI performance engineering with the MPI tool interface: The integration of MVAPICH and TAU, Srinivasan Ramesh, Aur\u00e8le Mah\u00e9o, Sameer Shende, Allen D. Malony, Hari Subramoni, Amit Ruhela, Dhabaleswar K. (DK) Panda, Parallel Computing, 2018 4. Lossy all-to-all exchange for accelerating parallel 3-D FFTs on hybrid architectures with GPUs, S. Cayrols, J. Li, G. Bosilca, S. Tomov, A. Ayala and J. Dongarra, 2022 IEEE International Conference on Cluster Computing (CLUSTER), 2022 5. Using open-science workflow tools to produce SCEC CyberShake physics-based probabilistic seismic hazard models, Callaghan S, Maechling PJ, Silva F, Su M-H, Milner KR, Graves RW, Olsen KB, Cui Y, Vahi K, Kottke A, Goulet CA, Deelman E, Jordan TH and Ben-Zion Y,. Front. High Perform. Comput. 2:1360720, 2024 6. Accelerating Large Language Model Training with Hybrid GPU- based Compression, L. Xu, Q. Anthony, Q. Zhou, N. Alnaasan, R. Gulhane, A. Shafi, H. Subramoni, D. Panda, IEEE/ACM International Symposium on Cluster, Cloud, and Internet Computing 2024, May 2024. Research Publications The proposed project seeks to co-design and integrate two powerful tools \u2013 MVAPICH and TAU \u2013 to demonstrate the new possibilities for performance-guided control and optimization for two large scale applications \u2014 AWP-ODC and heFFTe. 1. What are the challenges in achieving cross-runtime coordination and performance engineering for HPC applications? 2. Is it possible to leverage newer features available in modern GPU computing, the MPI 4.0 standard, and high- performance networking hardware to deliver better performance for HPC applications through efficient performance engineering? 3. Can MVAPICH and TAU co-design be leveraged in heFFTe and AWP-ODC to determine the reasons and guide resolutions for current strong scalability limitations in these applications? 4. How to reduce MPI communication costs for memory- bound heFFTe and AWP-ODC through new MPI features and integration with application-specific designs, mixed- precision algorithms, and real-time data compression? Supported by: OAC-2311830, OAC-2311831, OAC-2311832, OAC-2311833 Future Work Software Release, Community Engagement and Metrics MVAPICH (Initial Results) HeFFTe (Initial Results) TAU (Initial Results) AWP-ODC (Initial Results) Proposed integrated MPI profiling and performance engineering framework for MVAPICH and TAU, aiding HPC applications (AWP-ODC and heFFTe) Strong scalability on 3D FFTs of size 10243, using 24 MPI processes (1 MPI per Power9 core) per node (blue), and 24 MPI processes (4 MPI per GPU-V100) per node (red) Use T", "label": "poster"}
{"text": "ENOLOGICAL AND NUTRACEUTICAL POTENTIAL OF SOME GRAPE VARIETIES TOLERANT TO DOWNY MILDEW AND POWDERY MILDEW Fabiola De Marchi, Mirko De Rosso, Massimo Gardiman, Luigi Sansone,Annarita Panighel, Riccardo Flamini Council for Agricultural Research and Economics \u2013 Research Center for Viticulture & Enology, Viale XXVIII aprile, 26 \u2013 31015 Conegliano (TV), Italy Macrowine 2021 Virtual Verona, June 23-30 2021 Conclusions Study of oenological potential of grapes coupled to evaluation of the experimental wines produced in 2019 and 2020 showed that these varieties have a high potential to produce both still and sparkling wines suitable to match the consumers\u2019 satisfaction. Cabernet Cortis has a secondary metabolites profile which makes this variety suitable to produce wood-aged wines with floral notes. Souvignier gris is characterized by the presence of a- terpineol (floral aroma) and of interesting stilbenes which confer nutraceutical properties to the wines. Johanniter, characterized by high levels of geraniol, has a high aptitude to produce aromatic sparkling wines. Semi-aromatic character of Bronner makes this variety interesting for producing fresh and fruity still white wines. Spreading of these resistant varieties can promote the development of eco-sustainable viticulture at medium-high altitudes, such as Belluno Prealps and low Dolomites, an area which is of increasing interest in the context of the ongoing climate changes. Introduction Since 2012 the Veneto Region regulations allow the cultivation of twenty hybrid grapevine varieties tolerant to downy and powdery mildew, the main fungal diseases affecting grapevines. These varieties are characterized by high vigor and grape productivity, require a reduced pesticide use, and are suitable to develop sustainable viticulture in mountain areas located at medium altitudes (400-800 m a.s.l.), such as Veneto higher foothills and lower areas of Dolomites (North-East of Italy). The main aim of project VINIRES (started in 2018) is to evaluate the enological potential of four resistant vine varieties and their aptitude to produce high-quality wines: three white grape cultivars (Souvignier gris, Johanniter, Bronner), and the red grape cv Cabernet Cortis. The metabolomics study performed using high-resolution mass spectrometry techniques (UHPLC/QTOF) provided the complete profiles of the metabolites which determine the enological potential of the varieties. They include polyphenolic compounds belonging to the chemical classes of anthocyanins (natural colorants), flavonols, flavanols and procyanidins (antioxidant and astringent compounds), trans-resveratrol and stilbenes (nutraceutical compounds), and aroma glycoside precursors responsible for fruity/floral and floral/spicy notes of wines. Experimental Samples. Ripe grapes of varieties Cabernet Cortis, Bronner, Souvignier gris, and Johanniter were collected in 2019 and 2020 from vineyards located in Belluno province (Italy). Grape berries were randomly collected from different vines and immediately frozen at -20 \u00b0C until sample preparation for analysis. Sample preparation. Twenty berries were weighed and homogenized using liquid nitrogen. The resulting powder was added of pure methanol by a ratio of 1:2 w/v and 200 \u00b5L of internal standard 4,5,7-trihydroxyflavanone of 520 mg/L solution (Sigma-Aldrich, Milan, Italy). Extraction was carried out at room temperature for 20 min. The extract was centrifuged at 4200 rpm for 12 min at 18 \u00b0C and filtered by a 0.22 \u00b5m GHP Acrodisc filter (Pall) by collecting the solution in a vial for analysis. For each sample, two replicate analyses were performed. UHPLC/QTOF analysis. Extracts were studied by using an Ultra-High Performance Liquid Chromatography (UHPLC) Agilent 1290 Infinity system coupled to Agilent 1290 Infinity Autosampler (G4226A) and Agilent 6540 accurate-mass Quadrupole-Time of Flight (Q-TOF) Mass Spectrometer (nominal resolution 40.000) equipped with Dual Agilent Jet Stream Ionization source (Ag", "label": "poster"}
{"text": "AstroSat observations of long-duration X-ray superflares on active M-dwarf binary EQ Peg Subhajeet Karmakar1, Sachindra Naik1, Jeewan C. Pandey2, and Igor S. Savanov3 (1) Physical Research Laboratory, Navrangapura, Ahmedabad 380009, India (2) Aryabhatta Research Institute of observational Sciences (ARIES), Manora Peak, Nainital 263002, India (3) Institute of Astronomy, Russian Academy of Sciences, ul. Pyatniskaya 48, Moscow 119017, Russia We present a comprehensive study of three large long-duration flares detected on an active M-dwarf binary EQ Peg using Soft X-Ray Telescope of the AstroSat observatory. The peak X-ray luminosities of the flares in the 0.3 -- 7 keV band are found to be within ~4-10 \u00d7 1030 erg s-1. Spectral analysis indicates the presence of three temperature corona with the first two plasma temperatures remain constant during all the flares and the post-flare. The flare-temperature peaked at 56, 40, and 31 MK, which are 2.5, 1.8, and 1.4 times more than the minimum value, respectively. The peak emission measures are found to be 1.16 -- 5.64 \u00d7 1053 cm-3, whereas the abundances peaked at 0.7 -- 1.2 times the solar abundances. Using quasi-static loop modeling, we derive loop-lengths for all the flares as 2.7 \u00b1 1.4 \u00d7 1011, 3.9 \u00b1 1.5 \u00d7 1011, and 6.4 \u00b1 2.4 \u00d7 1011 cm, respectively. The estimated energies of all three flares are >1033-35 erg, putting them in a category of Superflare. All three superflares are also found to be the longest duration flares ever observed on EQ Peg. Contact: subhajeet09@gmail.com CoolStars-20.5 -- virtually cool -- 2-4 March 2021", "label": "poster"}
{"text": "Figure 1. The average daily PM10 and NO2 concentration in Stuttgart December 2004 (www.stadtllima-stuttgart.de). Red bars: days > 50\u03bcg/ m3 Black line: velocity of wind Orange bars: days < 50\u03bcg/m3 Blue line: NO2 concentration Blue bar: weekend, public holiday Green Walls for Clean Air Katrin G\u00f6lsdorf, Hans M\u00fcller Helix Pflanzen GmbH Marcus J. Collier School of Geography, Planning & Environmental Policy, University College Dublin, Ireland Introduction Air quality influences health and well being and pollutants like fine dust particles have the greatest impact on health. Their noxious effects are dependent on the particle size and the substance of content. Fine dust with a smaller diameter than 10\u00b5m can be transported to the bronchi and bronchioles. But more dangerous are particles less than 2,5\u00b5m. They directly enter the bloodstream through the alveolus. Studies from the WHO (Ostro, 2004) show that fine dust contaminated air reduces life expectancy by about 10 months. In Germany, measurements have been taken on fine dust since the 80\u2019s, and recently there have been attempts to improve German air quality using new action plans and providing incentives to fight air pollution. Nevertheless, threshold values for fine dust have been exceeded, especially in congested urban areas. 20% of all measuring stations in Germany exceeded the maximum allowed daily threshold value for fine dust on more than 35 days per year with more than 50\u03bcg of fine dust (PM10) per cubic meter of air [\u03bcg/m3] averaged across the day. Stuttgart is one of the regions with the highest fine dust concentrations in Germany (figure 1). REFERENCES Ostro B. (2004) Outdoor Air Pollution: assessing the environmental burden of disease at national and local levels. Geneva, World Health Organisation. WHO Environmental Burden of Disease Series, No.5. Ottel\u00e9, M., van Bohemen, H. D. and Fraaij, A. L. A. (2010) Quantifying the deposition of particulate matter on climber vegetation on living walls. Ecological Engineering, 36 (2), 154-162. Pugh, T.A.M., MacKenzie, A.R., Whyatt, J.D. and Hewitt, C.N> (2012) Effectiveness of green infrastructure for improvement of air quality in urban street canyons/ Environmental Science & Technology, 46 (14), 7692\u20137699. Reznik, G. and Schmidt, E. (2009) Reduction of emissions by vegetation \u2013 dry collection and wet resuspension of fine dust particles on ivy. GRdL 69 (10), 434 \u2013 438. www.gefahrstoffe.de/gest (in German). Can plants help to improve the air quality? People have often complained about Ivy on buildings, but research by Helix Pflanzen GmbH, a company that is specialised in the cultivation of ivy species and the development of green wall technology, is shedding new light on an old problem. Using a cultivated variety of ivy (Hedera helix \u2018W\u00f6rner\u2019), experiments were carried out that illustrated the binding effect that this Ivy has on fine dust particles. This is particularly important in urban areas, where fine dust can lead to significant impacts on quality of life. Results In 2008 Helix-Pflanzen GmbH collaborated with the University of Wuppertal to investigate fine dust capture by ivy (Hedera helix \u2018W\u00f6rner\u2019). The cleansing efficiency of this variety of plant was described by the fraction that could be removed by washing under active overhead irrigation as a function of surfaces, dimensions and mass. From the measuring results it was shown that Hedera helix \u2018W\u00f6rner\u2019 contributes to the particulate matter separation. This is characterised by a rain-induced leaf cleaning. Hedera helix \u2018W\u00f6rner\u2019 can significantly collect fine dust on its leaf surface. Particles < 5\u03bcm were deposited during low water flow velocity. If there is enough rain water and drop energy, particles > 5\u03bcm will be washed off the leaf surface (Reznik & Schmidt, 2009), shown in figure 2. Conclusion While Ottl\u00e9 et al. (2010) show that ivy can capture many polluting compounds, while also mitigating the effects of the urban heat island, the air \u2018cleaning\u2019 potential of these plants", "label": "poster"}
{"text": "OBJETIVO R Comparar y predecir la evoluci\u00f3n de la materia org\u00e1nica del suelo (SOM) en el tiempo y con respecto a la fracci\u00f3n de cobertura del arbolado, a trav\u00e9s de un modelo obtenido mediante un an\u00e1lisis de los datos recogidos durante los 12 a\u00f1os que abarca este estudio. INTRODUCCI\u00d3N r La estabilizaci\u00f3n del carbono del suelo juega un papel clave en el ciclo global del carbono. CONCLUSIONES R La proporci\u00f3n de materia org\u00e1nica en el suelo se ve directamente influenciada por la cobertura del arbolado debido a la ausencia de luz en las capas inferiores del sistema, afectando as\u00ed a la tasa de mineralizaci\u00f3n y modificando en consecuencia la composici\u00f3n del sotobosque al agregarse, adem\u00e1s, un material acidificante al suelo como son las ac\u00edculas ca\u00eddas. Por todo lo anterior, tratamientos culturales como la poda se convierten en recomendables con objeto de facilitar la incorporaci\u00f3n de la materia org\u00e1nica al suelo. Financiaci\u00f3n obtenida por el Programa de Desarrollo e Innovaci\u00f3n H2020 a la red tem\u00e1tica europea Agroforestry Innovation Network (AFINET, n\u00ba727872) y la XUNTA DE GALICIA (Ayudas de Consolidaci\u00f3n y Conseller\u00eda de Cultura, Educaci\u00f3n e Ordenaci\u00f3n Universitaria (\"Programa de axudas \u00e1 etapa posdoutoral DOG n\u00ba122, 29/06/2016 p.27443, exp: ED481B 2016/071-0\"). Este trabajo se llev\u00f3 a cabo por la USC para contribuir a los objetivos de la Global Research Alliance sobre gases de efecto invernadero en la agricultura (www.globalresearchalliance.org). La informaci\u00f3n mostrada no debe ser considerada como que representa el punto de vista de la Alianza en global o sus representantes.Financiaci\u00f3n obtenida por el Programa de Desarrollo e Innovaci\u00f3n H2020 a la red tem\u00e1tica europea Agroforestry Innovation Network (AFINET, n\u00ba727872) y la XUNTA DE GALICIA (Ayudas de Consolidaci\u00f3n y Conseller\u00eda de Cultura, Educaci\u00f3n e Ordenaci\u00f3n Universitaria (\"Programa de axudas \u00e1 etapa posdoutoral DOG n\u00ba122, 29/06/2016 p.27443, exp: ED481B 2016/071-0\"). Este trabajo se llev\u00f3 a cabo por la USC para contribuir a los objetivos de la Global Research Alliance sobre gases de efecto invernadero en la agricultura (www.globalresearchalliance.org). La informaci\u00f3n mostrada no debe ser considerada como que representa el punto de vista de la Alianza en global o sus representantes. 2 160 320 480 No fertilizado Fert. con lodos 9 tratamientos X 3 r\u00e9plicas Encalado / no Mineral Lolium perenne L. Dactylis glomerata L. Trifolium repens L. Primavera y oto\u00f1o 1998-2012 ANOVA y LSD test Pinus radiata D. Don 1667 \u00e1rboles ha -1 Interacci\u00f3n entre la materia org\u00e1nica y la cubierta arb\u00f3rea en sistemas silvopastorales establecidos en Galicia bajo Pinus radiata D. Don Francisco Javier Rodr\u00edguez-Rigueiro, Mar\u00eda Rosa Mosquera-Losada, Antonio Rigueiro-Rodr\u00edguez, Nuria Ferreiro-Dom\u00ednguez s Escola Polit\u00e9cnica Superior. USC. Campus de Lugo. Benigno Ledo s/n. 27002, Lugo.", "label": "poster"}
{"text": "Title Influence of pulse duration on intracellular calcium concentration for sub-10 ns pulses. Authors Lynn Carr1,2 Cristiano Palego2 Delia Arnaud-Cormos1 Philippe Leveque1 Affiliations: 1. Univ. Limoges, CNRS, XLIM, UMR 7252, F-87000 Limoges, France 2. School of Electronic Engineering, Bangor University, UK. Keywords: Intracellular calcium, nsPEF, glioblastoma Introduction Calcium ions (Ca2+) play a key role in a wide range of cellular processes. Intracellular calcium concentrations [Ca2+]i are known to increase following nanosecond pulsed electric field (nsPEF) exposure. To date there is limited information on how nsPEF, with a duration of less than 10 ns, affect calcium levels within cells. This study aims to characterise changes in [Ca2+]i following application of sub-10 ns pulses. Methods Changes in [Ca2+]i were visualised in U-87 MG cells loaded with 0.5 \u00b5M FLUO-4, AM. Cells were imaged, in either a standard HBSS solution or a calcium free HBSS solution, by epifluorescence using a Leica DMI6000 microscope with a 63x objective. Using two steel electrodes separated by a gap of 300 \u00b5m, with 50 \u03a9 impedance in parallel and an nsPEF generator with 50 \u03a9 output impedance, cells were exposed to a single pulse of 10, 8, 6, 4 or 2 ns duration, with an electric field intensity of 250 kV/cm. Change in fluorescence for each duration was averaged from 5 separate experiments with at least 3 cells per experiment. Results In standard HBSS solution all pulse durations caused immediate increases in [Ca2+]i. The amplitude of the increase was dependent on pulse duration. 2 and 4 ns pulses caused similar maximum fold increases in fluorescence of around 1.3, with fold increases of 2, 4.2 and 5.2 observed for pulses of 6, 8 and 10 ns respectively. The 2 ns pulse reached maximum fluorescence in 71 seconds after pulse application, for the other pulse durations it was reached in around 33 seconds. Within a minute of the pulse, for all durations except 2 ns, fluorescence had started to return towards baseline levels. By the end of the imaging period (2", "label": "poster"}
{"text": "Poly(vinyl alcohol) molecular bottlebrushes nucleate ice E-mail address: P.Georgiou@warwick.ac.uk 1 Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK @Georgiou_PG @LabGibson 3 Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK 2 Department of Physics, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK warwick.ac.uk/go/panagiotis_georgiou P. G. Georgiou,[1] N. L. H. Kinney,[1] I. Kontopoulou,[1] A. N. Baker,[1] S. A. Hindmarsh,[2] A. Bissoyi,[1] T. R. Congdon,[1] T. F. Whale,*[1] M. I. Gibson*[1],[3] achieved by the \u201csplat assay\u201d, whereby small ice crystals are formed at \u201380 \u00b0C , then allowed to grow at \u2013 8 \u00b0C, and their growth measured -78 ?? MOTIVATION Cryopreservation using Antifreeze Glycoprotein (AFGP) mimics Biggs et al., Macromol. Biosci. 2019, 19, 1900082 AFGPs are found in polar fish species and can slow ice crystal growth and therefore improve cryopreservation. Several synthetic and peptidomimetic macromolecules have shown great potential as cryopreservatives. Georgiou et al. Manuscript Submitted, 2022 \u2022 When the size of an AFP increases, it can become an ice nucleating protein. \u2022 Shown with modelling and experimentally. THIS WORK High-density brushes via \u201cgrafting-through\u201d: Bottlebrushes with different side-chain densities were designed via ROMP and RAFT polymerization. Selective hydrolysis of the acetate esters of the poly(vinyl acetate) (PVAc) side chains of the PVAc bottlebrush precursors resulted on the preparation of PVA bottlebrushes. Low-density brushes via \u201cgrafting-to\u201d: Assessment of ice recrystallization inhibition (IRI) activity and ice binding Increase in IRI activity compared to linear PVA Bottlebrushes (high and low density) inhibiting below 0.1 mg.mL-1. Assessment of ice nucleation activity +PBS + \u201cSplat assay\u201d Ice shaping (in sucrose solutions): PVA graft copolymers and bottlebrushes lead to more faceting of ice crystals, compared to linear PVA as the large polymers can span multiple crystals No additive Synthetic approach \u00d8 High-density bottlebrushes were observed to nucleate ice at average temperatures as warm as \u201319.2 \u00b0C which is unprecedented for a fully synthetic soluble material. \u00d8 Low-density PVA brushes also favored nucleation in although they nucleated ice at colder temperatures Microliter scale droplet freezing assay ACKNOWLEDGEMENTS The most active and widely studied synthetic ice-binding polymer is poly(vinyl alcohol) (PVA) well-known to effectively block the recrystallization of ice. Molinero et al., J. Am. Chem. Soc. 2019, 141, 18, 7439\u20137452 active inactive OH n PVA HO O H n PEG Koop et al., J. Phys. Chem. Lett. 2019, 10, 5, 966\u2013972", "label": "poster"}
{"text": "Warszawa Wroc\u0142aw Szczecin Gda\u0144sk Olsztyn Krak\u00f3w Pozna\u0144 Delimitation of species in Lepocinclis ovum complex (Euglenida) Katarzyna Chaber*, Maja \u0141ukomska-Kowalczyk*, Alicja Fells*, Bo\u017cena Zakry\u015b* *Institute of Evolutionary Biology, Faculty of Biology, Biological-Chemical Research Centre, University Of Warsaw Background The aims of the study Materials and methods Results Fig. 3. Consensus Bayesian tree based on 79 nSSU rDNA sequences. (1) significant increase of the number of sequences representing the L. ovum-like taxa on phylogenetic trees; (2) comparative morphological and molecular research on new strains (=isolates); (3) estimation of morphological and genetic diversity and verification of morphological diagnostic features for particular taxa (well-established clades) on a molecular phylogenetic tree; (4) reconstruction of phylogenetic relationships; (5) taxonomic verification, amending diagnoses, and designating epitypes for well-distinguished taxa, particularly for L. ovum and L. globulus. Using environmental sampling and nuclear SSU rDNA sequencing, we delimited species within the group of Lepocinclis ovum-like taxa. Apart from L. ovum and L. globulus, 13 other species were distinguished and four taxa (L. conica comb. nov., L. fominii comb. nov., L. gracilicauda comb. nov., and L. pseudofominii nom. nov.) had their taxonomic ranks changed. For all verified species, diagnostic descriptions were amended and epitypes designated, particularly for L. ovum and L. globulus. Identification of many common species of autotrophic euglenids is still problematic due to unsolved controversies in their taxonomy. Lepocinclis ovum (Ehren.) Lemmermann 1901 and L. globulus Perty 1849 are such problematic species. Although Lepocinclis ovum is recognized as a cosmopolitan and common species, and Lepocinclis globulus is the type species of the genus Lepocinclis, their correct identification is nearly impossible. The reason is that over 30 morphologically similar taxa appear in the literature, but no good diagnostic features exist to distinguish most of them. Fig. 1. a) original Ehrenberg's drawing of L. ovum, b) morphology of L. ovum, c) morphology of L. globulus. a b c The samples were collected during seven vegetation seasons (2012-2018) from 30 eutrophic water bodies in Poland. DNA was obtained from the cells (20-400) isolated with a micropipette. Morphological and molecular features were studied for taxa isolated from the environment and for two strains from algae collections. Phylogenetic analyses were conducted on 54 sequences of nSSU rDNA which were used to calculate maximum likelihood and Bayesian trees. Fig. 2. Map illustrating sampling locations in Poland. This work was supported by the OPUS 2016/23/B/NZ8/00919 grant from the National Science Centre, Poland. \u0141ukomska-Kowalczyk, M., Chaber, K., Fells, A., Milanowski, R. & Zakry\u015b, B. 2019. Molecular and morphological delimitation of species in the group of Lepocinclis ovum-like taxa (Euglenida). J. Phycol. 56:283-99. Zakry\u015b, B., \u0141ukomska-Kowalczyk, M., Chaber, K. Fells, A., 2020. Typification of Lepocinclis ovum (Ehrenberg) Lemmermann (Euglenophyta), a widespread freshwater species. Notulae Algarum No. 144.", "label": "poster"}
{"text": "Growing in colder climate than seed origin Growing in warmer climate than seed origin Photo Courtesy of Greg O'Neill Climate Adapted Seed Tool (CAST) www.ReforestationTools.org 2050 A Crisis and Opportunity \u2022 California forests are not adapted to rapidly changing climate conditions. \u2022 With climate-adapted seed transfer we can take proactive steps to adapt forests to climate change. Expected Impacts of Seed Transfer Expected Impacts\u2014if deployed across private land in CA starting in 2021 By 2050 By 2060 Additional CO2 Sequestered [million tonnes/yr] 2.3 4.1 Market Value of Additional CO2 Sequestered [million USD/yr] $77 $138 Additional % of Net 2018 CA GHG Emissions Sequestered [%/yr] .5% 1% Additional Timber Production [million board-ft/yr] 142 256 Climate Adaptation Mismatch Tree populations tend to be genetically adapted to their local historical climate conditions. But the climate is changing fast. Trees are long-lived and can\u2019t disperse as effectively as animals to track their suitable climate. Reforestation is an opportunity to help trees move to reach their ideal climate conditions. Climate Transfer Functions CAST uses climate-transfer functions fit to data from seed-transfer experiments to estimate the relative growth rate (e.g., growth, survival) of each candidate seed source. An evidence-based tool to improve reforestation outcomes. \u2022 Trees grow to become resistant to fire more quickly \u2022 Greater carbon sequestration \u2022 Greater timber production \u2022 Forest Health \u2022 Reduced mortality \u2022 Faster recovery into desired habitat types Seed-Transfer Datasets We\u2019re working to incorporate data from 368,000 trees planted in seed-transfer experiments across western North America into CAST. Forward thinking scientists began establishing these experiments in 1910 and scientists are still working to establish new experiments. However, the bulk of our data currently comes from outside California. Scaling up the number of seed transfer experiments planted in California\u2019s diverse regions will be critical to best adapting our forests to climate change. Greg O'Neill BC Forest Service Jessica Wright US Forest Service Joe Stewart UC Davis Species abco abma acma alru pico pije pimo pien pipo pisi potr psme qulo thpl tshe N. Provenances 14 9 42 47 184 3 145 182 42 30 180 77 95 10 57 N. Sites 5 5 3 2 60 3 7 26 10 9 3 6 2 6 5 N. Trees 9.1k 3.3k 13.8k 4.1k 70.7k 4.6k 22.1k 110k 10k 31.9k 9k 25.3k 7k 4.1k 42.7k Last Meas. Age [field-yrs] 18-26 18-26 10 10 20-35 41 16 10-15 8-80 10-15 3 17- 100 6 15 5-25 Planting Yr(s) 1976- 1979 1976- 1979 2008- 2009 1995 1974 1973 1988 2000- 2005 1910 - 1992 2000 2000- 2007 1915- 1975 2014- 2015 1991 1993- 2005 Spatial Accuracy and Uncertainty Climate is a Moving Target Mean Annual Temperature [\u00b0C] Percent Decline in Productivity Due to Climate-Adaptation Mismatch Probability Probability Sung et al 2021 Team PICO, RCP8.5 Ensemble Seed Source Planting Site Jim Thorne UC Davis Steve Ostoja USDA Climate Hub Jessie Godfrey UC Davis Selecting seed for warming climate conditions inherently involves tradeoffs between optimizing for colder conditions in the near term and hotter conditions in the long term. CAST currently defaults to balancing this tradeoff by to optimizing for anticipated climate conditions \u2248 20 yrs. in the future. It also includes options for optimizing over longer or shorter time horizons. Ryan Boynton UC Davis % Decline in Productivity Without CAST CAST allows users to input precise spatial information and is also backwards compatible with California\u2019s legacy system of seed zones and elevation bands. Because of considerable climatic heterogeneity (i.e., uncertainty) within the legacy spatial units, users who use precise spatial information are likely to achieve better outcomes (i.e., \u2248 5% greater growth rates). % Decline in Productivity without CAST", "label": "poster"}
{"text": "A grid of synthetic spectra for the study of multiple populations on globular clusters Vinicius Branco1, Paula Coelho1, and Ariane Lan\u00b8con2. Instituto de Astronomia, Geof\u00b4\u0131sica e Ci\u02c6encias Atmosf\u00b4ericas, Sao Paulo, Brazil.1 Observatoire astronomique de Strasbourg, Strasbourg, France.2 Email: vbranco@usp.br Summary Globular Clusters are challenging and fascinating astronomy objects. Once understood to be simple stellar populations, it is now known that stars in massive GCs present chemical variations not expected by the current theoretical predictions. In this work, we have calculated stellar spectra to study the integrated properties of GCs, considering three iron metallicities and two generation of stars \u2014 a primordial one following the pattern of galactic halo stars and a second one with anti-correlated CNONa abundances. We show that the modelled stellar population spectra present signatures of the CNONa anti-correlations, thus a\ufb00ecting our interpretation of the integrated spectrum of a GC and the Lick indices. Before applying our models to extragalactic environments, where only the integrated spectra of GCs can be accessed, we are calibrating our stellar spectra grid to a sample of metal-poor empirical spectra drawn from the X-Shooter Library. This will allow us to construct a more reliable grid of synthetic spectra to study the multiple populations on GCs. Introduction Globular Clusters (GCs) are invaluable to advance our knowledge of both galactic and extragalactic astronomy. The last decade is seeing a change of paradigm regarding these systems: once understood to be simple stellar populations, now evidence accumulates that nearly all massive Galactic GCs harbour multiple populations (MPs) of stars. Yet the stellar populations models to date often still study these systems on the basis of simple stellar populations. Our work aims at improving stellar population models of integrated spectra by incorporating what is already known in terms of the chemical mix- tures of the multiple populations. For that, we build on our previous work and in synergy with the POPSYCLE collaboration [1]. We believe this will allow us to better exploit the data of extragalactic GCs, expected to be observed in the coming years. Methodology Our recent work Branco (2020, [2], [3], \u201cB20\u201d) and Branco et al. (in prep), followed up on the \ufb01rst e\ufb00orts by Coelho et al. (2011, \u201cC11\u201d, [4]) in understanding the e\ufb00ect of MPs in the integrated light of GCs. To calculate the models and the synthetic spec- tra, we used ATLAS12 and SYNTHE codes [5], with the Sun to calibrate our atomic and molecular ingredients. We produced two stellar population synthesis (SPS) models, covering three metallicities. For each [Fe/H] value, we calculated \u03b1-enhanced models representing a \ufb01rst generation of stars and a \u03b1\u2212and helium-enhanced second generation including the observed chemical abundance variations on C, N, O and Na on stars of Galactic GCs. Figure 1 shows how the SPS integrated spectra contrast to each other at various metallicities, as well as the residual \ufb02ux di\ufb00erence between \ufb01rst and second generation spectra. Figure 1. SPS integrated spectra representing the \ufb01rst (purple) and second (yellow) generation of stars for three metallicities (top panel) and their residual \ufb02ux di\ufb00erence (i.e., \ufb01rst generation \ufb02ux minus second generation \ufb02ux, bottom panel). Results For a metallicity of [Fe/H] = -0.7, C11 found that the Lick indices appreciably a\ufb00ected by the chemical abundance anticorrelations, as expected by the presence of MPs, were CN1, CN2, Ca4227, G4300 and NaD. Later on, B20 produced a grid of stellar spectra expanding the metallicity coverage of C11 towards less and more metallic systems. The e\ufb00ects on the Balmer lines were con\ufb01rmed in B20, and for the \ufb01rst time the in\ufb02uence of the MPs on those Lick indices were found in di\ufb00erent metallicity regimes. Conclusion and Perspectives We have con\ufb01rmed the results by C11 and expanded the metallicity coverage of that study i", "label": "poster"}
{"text": "Collaborative Research: CyberTraining: Pilot: Research Workforce Development for Deep Learning Systems in Advanced GPU Cyberinfrastructure OAC-2306184/OAC-2330364 PI of OAC-2306184: Tong Shu, Department of Computer Science and Engineering, University of North Texas PI of OAC-2330364: Xin Liang, Department of Computer Science, University of Kentucky Training Program on Deep Learning Systems in Advanced GPU Cyberinfrastructure 2023 and 2024 https://dlgpu-workshop.github.io Training Syllabus Lecture Modules \u2022 For all students \u27a2Deep Neural Network Training and Inference on GPUs (Dr. Tony Luo) \u27a2Deep Learning Models I: Convolutional Neural Network and Physics- Informed Neural Network (Dr. Tony Luo) \u27a2Deep Learning Models II: Graph Neural Network and Transformer (Dr. Tong Shu) [New in 2024] \u27a2Resource-Aware Deep Learning Model Exploration on GPUs (Dr. Tong Shu) \u27a2Basic CUDA Programming (Dr. Tong Shu) \u27a2GPU Architectures and CUDA Programming (Dr. Tong Shu) \u2022 For CSE students \u27a2Advanced CUDA Programming (Dr. Xin Liang) \u27a2CUDA Programming for Deep Learning Applications (Dr. Xin Liang) \u27a2CUDA Libraries, Kernel Profiler, and Performance Analysis Tool (Dr. Iraklis Anagnostopoulos) \u27a2Deep Learning on TPUs (Dr. Iraklis Anagnostopoulos) [New in 2024] \u2022 For non-CSE students: \u27a2CNN-based Hydrological Connectivity Modeling (Dr. Ruopu Li) \u27a2PINN-Based Space Environment Nowcast (Dr. Daoru Han) Hands-on Exercise System https://github.com/SHUs-Lab/JupyterHubPlus \u2022 Configure JupyterHub for authentication and access of multiple users \u2022 Support CUDA C code block by modifying JupyterHub source code \u2022 Iterations with trainees and timely monitoring of progress on hands-on exercises Raw data (e.g., tabular data, images) Scientific/ Social Simulation/ Experiments DL-Driven Scientific Research Performance metrics (e.g., prediction accuracy, training time, resource efficiency) Search Space Neural Architecture | Hyper-Parameters | Resource Constraints GPUs of diverse capabilities (e.g., number of CUDA/tensor cores, peak TFLOPS, memory, bandwidth) PyTorch Model Exploration (NNI) Exploration Strategy Estimation Strategy Cross-model optimization Training control Search algorithms (e.g., evolutionary algorithm, reinforcement learning, bayesian optimization) Model generation with resource constraints Resource-Aware Neural Architecture Search CNN PINN Performance Modeling and Prediction DL inference DL training Nvidia GPUs Advanced CUDA Toolkit Architectures of State-of-the-Art GPUs PyTorch Convolutional-NN-based Hydrological Connectivity Modeling GPU-based DL Systems Advanced GPU CI DL App Benchmarks Geoscience Research Physics-Informed- NN-based Space Environment Nowcast Neural Network Intelligence (NNI) Resource-Aware DL Model Exploration Advanced Programming with Tensor Cores Latest Profiler: Nsight Compute, Nsight Systems DL Training and Inference on GPUs Libraries: cuBLAS, cuDNN, NCCL Interdisciplinary Projects \u2022 Project topics \u27a2Project 1: Accurate and time-efficient transformer inference on TPU architecture for drought classification (Summer 2024) \u27a2Project 2: Exploration of TPU architectures for optimized transformer performance in image detection of drainage crossings (Summer 2024) \u27a2Project 3: Accuracy-constrained efficiency optimization and GPU profiling of CNN inference for detecting drainage crossing locations (Summer 2023) \u27a2Project 4: Pareto optimization of CNN models via hardware-aware neural architecture search for drainage crossing classification on resource-limited devices (Summer 2023) \u27a2Project 5: Deep-learning model for optimization of an electrostatic Sieve for lunar regolith beneficiation (Summer 2024) \u27a2Project 6: Space environment modeling and uncertainty quantification with deep neural networks (Summer 2023) \u27a2Project 7: Reusing small pre-trained models for efficient large model training in natural language processing (Summer 2024) \u27a2Project 8: Real-time edge analytics for thermal infrared imagery and geological hazards with deep detection (Summer 2023) \u2022 ", "label": "poster"}
{"text": "Listening effort ratings for habitual and clear-Lombard speech as predicted by a glimpse measure Esther Janse1, Chen Shen1, & Martin Cooke2 1 Radboud University Nijmegen, the Netherlands 2 University of the Basque Country, Spain Background and RQs 1 High-Energy Glimpse proportion (HEGP) measure is known to predict speech-in-noise intelligibility 2 Intelligibility and listening effort are inversely related RQ1a Does HEGP predict listening effort ratings for speech presented in noise? RQ1b If so, does HEGP predict effort differentially for habitual and clear-Lombard speech? RQ2 Do acoustic-phonetic measures explain additional variance in effort ratings? Speech corpus and ratings \u2022 Multi-talker Radboud Lombard Corpus (subsample of 48 talkers) \u2022 Speech and listening effort ratings available on Zenodo (scan QR \uf0e0) \u2022 48 talkers reading 48 sentences, in both habitual and clear-Lombard style (48*48*2=4608 sentences) \u2022 Listening effort ratings collected online for sentences, presented in speech-shaped noise (-6 dB SNR) \u2022 230 online raters; each unique sentence rated by 2-3 raters \u2022 Rating on 7-point listening effort scale Extremely effortful to understand Not effortful at all to understand Acoustic measures High-Energy Glimpse Proportion \u2022 Speech-in-noise mixture passed through filter bank \u2022 HEGP quantifies speech-dominant High-Energy glimpses from the noisy speech \uf0e0 HEGP score (0-1) per sentence Statistical modelling and results Model 1 (HEGP) Model 2 (HEGP plus additional acoustic measures) model1=lmer(Rating ~ hegpC*Style+ Gender + (1|SentenceID) + (1|Rater) + (1+Style|Speaker) model2= (same fixed and random structure as model 1) + scaled(F0range + F0median+artic_rate + HamI) Number of obs: 11040, Rater, 230; Speaker, 48; SentenceID, 48 (sum coding for categorical variables) Identical dataset and contrast coding as for model 1 Fixed effects \u03b2 SE t p \u2013level HEGP -8.93 0.41 -21.93 *** Style -0.55 0.08 - 7.139 *** Gender (talker) 0.81 0.11 7.15 *** HEGP*Style <1 n.s. Marginal R2 (AIC) 0.34 (35159) Fixed effects \u03b2 SE t p\u2013level HEGP -7.93 0.41 -21.93 *** Style -0.44 0.08 - 5.31 *** Gender 0.77 0.12 6.38 *** HEGP*Style 0.69 0.62 1.12 n.s. F0 range -0.08 0.02 - 3.61 *** F0 median 0.06 0.03 1.91 . (<0.1) Articulation_rate 0.10 0.03 3.33 *** Hammarberg Index 0.06 0.03 2.22 * Marginal R2 (AIC) 0.35 (35136) YES NO YES Intelligibility in noise Listening effort HEGP and other acoustic measures ? Additional acoustic-phonetic measures \u2022 F0 range (in semitone) \u2022 F0 median (in semitone) \u2022 Articulation rate (syll/sec) \u2022 Hammarberg Index (\u0394 energy LF (0\u20132 kHz) and HF band (2\u20135 kHz; higher values index less vocal effort) Bottom line HEGP and other acoustic measures Listening effort Intelligibility in noise RQ1: HEGP equally strong predictor of effort across speaking styles RQ2: acoustic-phonetic measures explain some additional variance in listening effort \uf0e0 MORE EFFORT HEGP (centered) This project has received funding from the European Union\u2019s Horizon 2020 research innovation program under the Marie Sk\u0142odowska-Curie Grant No. 675324 (ENRICH). 1 2", "label": "poster"}
{"text": "Characterization methods for Shiga toxin-producing E. coli \u2013 a part of OH-HARMONY-CAP G.S Johannessen 1 \u2022 R. Tozzoli 2 \u2022 A. Pista 3 \u2022 C. Flink 4 \u2022 F. Alves3 \u2022 D. Bolton5 \u2022 M. Kirchner6 \u2022 N. Boisen7 1. Norwegian Veterinary Institute, \u00c5s, Norway \u2022 2. Istituto Superiore di Sanit\u00e0, Rome, Italy \u2022 3. National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal \u2022 4. Swedish Food Agency, Uppsala, Sweden \u2022 5. Teagasc Food Research Centre, Ashtown, Dublin, Ireland \u2022 7. Animal and Plant Health Agency, Addlestone, United Kingdom \u2022 7. Statens Serum Institut, Copenhagen, Denmark In summary, 41 laboratories responded that they tested for STEC, including human clinical (17), animal (13), food (24), feed (6) and environmental samples (11) [1]. For the typing of STEC, serotyping is commonly being used, although it is clear that the pathogenic potential of the isolates cannot be determined by serotypes alone and that all STEC are considered as pathogenic to humans [2]. A total of 25 and 15 labs performed O- and H-typing, respectively, using serological, molecular and a combination of these methods (fig 1). A total of 35 respondents tested their isolates for virulence-associated genes, where a majority tested for stx and eae genes. Approximately half of the labs testing for stx genes also carried out subtyping of these, while subtyping of eae was not common. From the responses to the questionnaire it was not possible to discriminate between laboratories using PCR or WGS for the detection of virulence genes, but we assume that both methods are employed. In addition 17 laboratories reported that they performed phylogenetic analyses, i.e. genetic comparisons to determine the relatedness of isolates (fig 2). While the literature search yielded around 130 hits, we also looked into recent publications from organizations such as EFSA and FAO/WHO [2,3]. Several different methods for typing and characterization of STEC have been tested, but serotyping and virulence gene profiling of stx genes and their subtypes seem to be the most used methods. For further characterization molecular methods such as PFGE and MLVA have been commonly used, but with recent developments in sequencing technology, many laboratories have implemented whole genome sequencing (WGS) based methods for further characterization of STEC, such as single nucleotide polymorphisms (SNP) and core and/or whole genome multi locus sequence typing (cg and/or wg MLST). References: [1] D-IA.2.2.OH-Harmony-Cap 3.2. 2021. https://zenodo.org/record/5788415#.Yjm6--fMKUk, [2] EFSA, 2020. DOI: https://doi,org/10.2903/j.efsa.2020.5967, [3] FAO/WHO, 2018. https://www.fao.org/documents/card/en/c/CA0032EN/ This poster is part of the European Joint Programme One Health EJP. This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under Grant Agreement No 773830. RESULTS METHODS The work package (WP) 3 of the OH-HARMONY-CAP project (One Health Harmonization of Protocols for the detection of foodborne pathogens and AMR determinants) concerns laboratory interoperability, i.e. the potential for using harmonized method across the human, veterinary and food sectors. Here we aimed to map characterization methods for Shiga toxin-producing E. coli currently in use, identify gaps and recommend a harmonised strategy for such methods. \u2022 A questionnaire was developed in WP3 to examine current practices in public health, veterinary, food testing and National Reference Laboratories and the responses from the questionnaire with respect to typing and characterization of STEC were analysed. \u2022 A literature search in PUBMED using the search string (Shiga toxin-producing Escherichia coli) AND (characterization methods) AND (typing methods) with criteria English language and publication period 2000 - 2021, was performed. \u2022 Other sources, such as EURL for E. coli, EFSA, ECDC, OIE and FAO/WHO were also examined. CONCLUSION AND PERSPECTIVES Molecular typing methods, including t", "label": "poster"}
{"text": "Bentheuphausia amblyops (Euphausiacea) Gennadas valens (Dendrobranchiata) vs. Amalopenaeus elegans (= Gennadas elegans) faut examiner les structures g\u00e9nitales / must examine the genital structures Nematocarcinus rotundus (Caridea) Acanthephyra purpurea (Caridea) Acanthephyra pelagica (Caridea) Notostomus elegans (Caridea) Crustac\u00e9s m\u00e9sop\u00e9lagiques (crevettes et krill) - relev\u00e9 d\u2019hiver 2024 NGCC Cabot Mesopelagic Crustaceans (shrimp and krill) - Winter Survey 2024 CCGS Cabot Plesionika martia (Caridea) Hymenopenaeus debilis (Dendrobranchiata) Systellaspis debilis (Caridea) Robustosergia robustus (Dendrobranchiata) Pasiphaea tarda (Caridea) G. valens fem. \u00e9pines / spines \u00e9pines / spines x Claude Noz\u00e8res (2024)", "label": "poster"}
{"text": "Motivation Applications for Modeling Life Science data in Wikidata. Tim E. Putman1, Sebastian Burgstaller-Muehlbacher1, Andra Waagmeester2, Chunlei Wu1, Andrew I. Su1, and Benjamin M. Good1 1 Department of Integrative, Structural and Computational Biology, the Scripps Research Institute, La Jolla, USA 2 Micelio, Antwerp, Belgium Wikidata provides an extensible open framework ideal for aggregating distributed data in a centralized database that supports: \u2022complex querying based a semantic data model \u2022providing data for domain speci\ufb01c web applications that allow the user to both read and write data A A) Semantic microbial data model consisting of a hierarchical taxonomic schema and separate entities for gene and protein. The nodes are Wikidata \u2018items\u2019 and \u2018properties\u2019 de\ufb01ne the relationships. B) Python based \u2018Bot\u2019 software for gathering data from different resources and reading and writing directly to Wikidata (https:// github.com/SuLab/WikidataIntegrator). Bacteria (Q10876) domain C. trachomatis 434/BU (Q20800254) strain trpA (Q21153861) gene TRPA (Q21153984) protein found in taxon (P703) parent taxon (P171) encodes (P688) encoded by (P702) subclass of (P279) Entrez ID (P351) gen. start (P644) gen. stop (P645) subclass of (P279) UniProt ID (P352) RefSeq ID (P637) molecular function (P680) locus tag (P2393) C. trachomatis (Q131065) species biological process (P681) cell component (P682) Data model and implementation B Figure2. NCBI Genome Assemblies. A) Various data sources for microbial genetic data. B) Cumulative sum of bacterial and eukaryotic genome assemblies submitted to NCBI GenBank by year. A B Scope and diversity of microbial data 0 10000 20000 30000 40000 50000 60000 70000 80000 90000 100000 Bacteria Eukaryotes Sequenced Genomes Modeling microbial interactions trpA C. trachomatis genome www.ncbi.nlm.nih.gov/ genome/ indole www.drugbank.ca/ Chlamydia trachomatis: genes www.ncbi.nlm.nih.gov/gene/ Human: indoleamine 2, 3-dioxygenase www.uniprot.org/ tryptophanase www.uniprot.org/ C.trachomatis: trp. synth. alpha and beta www.uniprot.org/ C.trachomatis: tryptophan synthase www.rhea-db.org C.trachomatis: trpRBA operon www.operondb.jp/ Akers et al. 2006 trpB trpR organismLabel Escherichia coli IAI39 Treponema denticola ATCC 35405 Yersinia enterocolitica subsp. enterocolitica 8081 Aeromonas hydrophila subsp. hydrophila ATCC 7966 Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio parahaemolyticus RIMD 2210633 Fusobacterium nucleatum subsp. nucleatum ATCC 25586 Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough Salinibacter ruber DSM 13855 Escherichia coli UMN026 Escherichia coli O104:H4 str. 2011C-3493 Escherichia coli O83:H1 str. NRG 857C A) The interactions between host, pathogen, microbiome, and small molecules that lead to pathogen persistence during a chlamydial infection in humans (originally hypothesized by Caldwell et al. 2003). Blue URLs indicate source of data and edges are de\ufb01ned by properties in Wikidata. B) SPARQL query results for organisms that are capable of producing indole . A B. Organisms that produce indole Acknowledgements We would like to thank Lynn Schriml and Elvira Mitraka of the University of Maryland, the members of The Apollo Project and the many members of the Wikidata community for valuable contributions to this project. References/Funding Caldwell et al. 2003 (PMID:12782678) Putman et al. 2016 (PMID:27022157) Burgstaller-Muehlbacher et al. 2015 (PMID: 26989148) This work is supported by the National Institutes of Health under grant GM089820, GM083924, GM114833 and DA036134. Domain Speci\ufb01c Portals into Wikidata A) WikiGenomes: a centralized model organism database for bacterial reference genomes that supports community annotation. B) Wikidata as the universal, community owned, backend database for any domain speci\ufb01c application. A B L-tryptophan www.drugbank.ca/ N-Formylkynurenine www.drugbank.ca/", "label": "poster"}
{"text": "Introducci\u00f3n Los procesos de fusi\u00f3n y solidi\ufb01caci\u00f3n de las nanopart\u00edculas de elementos puros y nanoaleaciones en la actualidad siguen atrayendo interes por sus propiedades especiales y posibles aplicaciones en diversos campos como cat\u00e1lisis, electr\u00f3nica, \u00f3ptica y hasta remediaci\u00f3n ambiental. Objetivos - Determinar el rango de temperatura donde ocurre la fusi\u00f3n de la nanoaleaci\u00f3n Fe-Al. - Determinar si el tama\u00f1o de la nanoaleaci\u00f3n in\ufb02uye en la temperatura de fusi\u00f3n. Procedimiento Se utiliza la simulaci\u00f3n con el m\u00e9todo de din\u00e1mica molecular para estudiar los procesos de fusi\u00f3n y solidi\ufb01caci\u00f3n de las nanopart\u00edculas de Al@Fe en concentraci\u00f3n de N-m para el aluminio y m para el hierro (siendo N el n\u00famero total de \u00e1tomos y m el n\u00famero de \u00e1tomos de Fe) con estructura core-shell. Es decir los \u00e1tomos de Al en el centro y en la capa externa los \u00e1tomos de Fe. Se han simulado varias concentraciones con velocidades de calentamiento de 2 K/ps y 10 K/ps en el rango de temperatura de 200 K a 1600 K. La simulaci\u00f3n se realiz\u00f3 con el software LAMMPS con potencial de interacci\u00f3n tipo EAM. Estructura interna y externa de la nanopart\u00edcula de 1157 \u00e1tomos a 200 K. Red de tipo FCC con par\u00e1metro de red 4.04 Anstron. Resultados Nanoaleaci\u00f3n de 1157 \u00e1tomos Nanoaleaci\u00f3n de 3907 \u00e1tomos Energ\u00eda total vs Temperatura para varias concentraciones. Con un calentamiento de 2K/ps Conclusiones - La transici\u00f3n de fase en la nanoaleaci\u00f3n de 1157 \u00e1tomos ocurre aproximadamente a 900 K. - La transici\u00f3n de fase en la nanoaleaci\u00f3n de 3907 \u00e1tomos ocurre aproximadamente a 1000 K. - El n\u00famero de estructuras de tipo FCC decrese. - Ambas nanoaleaciones muestran cierto grado de cristalinidad a 213 K aproximadamente. Transici\u00f3n de Fase en Nanoaleaciones de Hierro-Aluminio con Estructura Core- Shell: Estudio con Din\u00e1mica Molecular XXIV Simposio Peruano de F\u00edsica 2 al 6 Noviembre 2015 Universidad Nacional Mayor de San Marcos Shigueru Nagata, Zhenia Davalos, Justo Rojas Facultad de Ciencias F\u00edsicas, Universidad Nacional Mayor de San Marcos, Lima, Per\u00fa", "label": "poster"}
{"text": "U.S. Environmental Protection Agency Office of Research and Development EPA\u2019s Toxicity Forecaster (ToxCast) Research Effort Communications and Outreach Overview M. Linnenbrink National Center for Computational Toxicology, Office of Research and Development, United States Environmental Protection Agency Approach Stakeholder Groups Communication & Outreach Activities ToxCast Data Usage Stakeholder Workshop Feedback Monica Linnenbrink l Linnenbrink.Monica@epa.gov l 000-000-0000 III-1-576 \u2022 Promote use of ToxCast high-throughput screening data to inform a variety of chemical safety decisions \u2022 Increase meaningful involvement in the development of research and tools \u2022 Encourage two-way dialogue between stakeholders and EPA about ToxCast data \u2022 Provide regular updates about research progress and plans for the future research direction \u2022 Academic Institutions \u2022 Industry/Industry Trade Associations \u2022 Professional Societies \u2022 Non-Governmental Organizations \u2022 International Government Agencies \u2022 Environmental & Scientific Media \u2022 US EPA Regulatory Offices & Regions \u2022 Other US Government Agencies \u2022 US Congress \u2022 State Agencies & Municipalities \u2022 December 13, 2013 \u2013 EPA announced release of iCSS dashboard, ToxCast Phase II data and Data Challenges (news release, social media, blog) \u2022 Updated fact sheets and websites \u2022 Continued Social media: Twitter, blogs for Scientific Reports, Environmental Science & Technology, and Nature Biotech papers \u2022 Events: Webinars, workshops and Data Summit \u2022 Proactive outreach to scientific and environmental media \u2022 ToxCast research presented and promoted at scientific conferences \u2022 Research collaborations to exchange data and expertise (LOREAL, Health Canada, pharmaceutical companies, etc) \u2022 Feedback from stakeholders (surveys, qualitative) \u2022 Tutorial videos \u2022 Data challenges Recent scientific advances provide innovative solutions to persistent and pervasive issues facing risk-based chemical safety evaluations. US EPA has been using in vitro testing methods to accelerate the pace of chemical evaluations, reduce reliance on animals, and address the lack of data on thousands of chemicals. In 2013, EPA\u2019s Toxicity Forecaster (ToxCast) released high- throughput screening data on 1,800 chemicals. ToxCast is a multiyear effort launched in 2007 that uses high-throughput screening to expose cells or proteins to chemicals. The cells or proteins are then screened for changes in biological activity that may suggest toxic effects. ToxCast has the potential to limit the number of animal-based toxicity tests, while quickly and sufficiently screening large numbers of chemicals. ToxCast chemicals were screened for potential health effects using a battery of ~700 high-throughput screening assay endpoints. All data is publicly available for stakeholders to analyze and use to help inform chemical safety decisions. Applying ToxCast data to support regulatory decisions requires evolution of a risk assessment paradigm that has been used for decades. EPA recognized early that a communications and outreach strategy with the goal of increasing usage and analysis was needed to demonstrate the power of this information . Background Media Coverage 60% 13% 27% ToxCast Data Very Satisfied Satisfied Neither Satisfied or Dissatisfied Dissatisfied Very Dissatisfied Have not Used 13% 34% 20% 33% iCSS Dashboard Very Satisfied Satisfied Neither Satisfied or Dissatisfied Dissatisfied Very Dissatisfied Have not Used 27% 66% 7% Workshop improved understanding of data/tools and use of them Strongly Agree Agree Undecided Disagree \u2022 Media Coverage \u2022 BNA \u2022 Greenwire \u2022 Chemical Watch \u2022 Environmental Leader \u2022 ACC \u2022 Twitter stats: 7 tweets, 41 retweets, 15 favorites, reaching 145,880 individuals \u2022 Held two stakeholder workshops \u2022 Provide overview of high-throughput screening data \u2022 Presentations described ToxCast data \u2022 Provide early interpretation of data \u2022 Demonstrate how to access ToxCast data \u2022 Provide opportunity for stakeholder feedback during one-o", "label": "poster"}
{"text": "First Results of the 2021 FASER Calorimeter Test Beam Charlotte Cavanagh, University of Liverpool FASER is a new experiment at CERN designed to complement the LHC's ongoing physics programme, extending its discovery potential to light and weakly-interacting particles such as long-lived dark photons (A\u2019). These are characterised by a signature with two oppositely-charged tracks or two photons with very high energy (\u223cTeV) that emanate from a common vertex inside the detector. The FASER tracker consists of 72 double-sided silicon microstrip modules. \u2022 A 150 GeV muon beam with approx. 3.5M tracks was used to study local alignment in middle layer of 1 station \u2022 Local x and y residuals before (after) alignment shown in red (blue) displaying the results after alignment \u2022 Global alignment results are in progress \u2022 The test beam saw efficient data taking with good overall beam quality and purity \u2022 The relative calorimeter response to different electron energies and MIPs (high energy muons) were measured \u2022 Tracking studies have provided local alignment results \u2022 Preliminary results have been compared to simulation and fair agreement has been found in terms of energy resolution \u2022 Raw calorimeter data has been analysed and corrected to account for pre-shower, improving resolution \u2022 Analysis continues as an ongoing process, more than 150 million events were recorded during the week of the test beam \u2022 Detector once again situated in TI12, ready for data taking during Run 3 Experiment The main aims of the 2021 Test Beam are: \u2022 Calibration of calorimeter using electron (5-300 GeV) and muon (150 GeV) beams, scanning through 24 spatial points across 6 modules \u2022 Study uniformity of MIP response and pion scan Setup consists primarily of the tracking stations, the preshower and the calorimeter. Test Beam Tracking Studies \u2022 When the pre-shower sees more charge, the calorimeter sees less charge \u2022 A correction factor was derived and applied to calorimeter energy measurements to account for this imbalance in charge \u2022 The resulting calorimeter response increases mean charge/energy deposition and improves resolution Pre-shower Correction Outlook A full simulation of the calorimeter system is implemented in FASER\u2019s Calypso framework. \u2022 Specific test beam geometry designed to compare simulation to data \u2022 Crystal ball fitted to distributions to extract \u03bc and \u03c3, where \u03c3 is derived from width of crystal ball, converting to energy resolution (\u03c3/E) allows for direct comparison (see table) Corrected data - includes pre-shower correction, removal of noisy channels, 5 + 10 GeV data points excluded (limit of beam) to further reduce resolution Raw data - no corrections, event selection applied to waveform, \u03bc = deposited charge/beam energy Simulated data - no pre-shower correction, comparable to raw data, \u03bc = fraction of energy deposited in calorimeter Previous LHCb results - 2004 test beam extending to 100 GeV, using same ECAL modules but without a pre-shower, comparable to corrected data Next stage: calibrate response of calorimeter in terms of energy. Calorimeter Performance Tracking stations = 3 Planes per station = 3 Modules per plane = 8 FASER is supported by: Errors on plot are too small to be visible at this scale. Test Beam setup and event display.", "label": "poster"}
{"text": "Kyung-Ae Park(1), Hye-Jin Woo(2), Sung-Rae Chung(3), Seong-Hoon Cheong(3), Byung-Il Lee(3) (1) Dep. of Earth Science Education, Seoul National University, Seoul, Korea, Email: kapark@snu.ac.kr (2) Dep. of Science Education, Seoul National University, Seoul, Korea, (3) National Meteorological Satellite Center, KMA, Chungbuk, Korea Geo-KOMPSAT-2A (Geostationary Korea Multi-Purpose Satellite-2A, GK-2A), which was launched successfully on 5 December 2018, is a second geostationary satellite of Korea, following on the Communication, Ocean and Meteorological Satellite (COMS). Advanced Meteorological Imager (AMI) on the GK-2A, which is quite a similar to the ABI of GOES-16/17 and the AHI of Himawari-8/9, has sixteen channels and has an overall wavelength range from 0.4 to 13 \u03bcm. The spatial resolution is 0.5 km or 1 km for the visible channels and 2 km for the infrared channels. The temporal resolution is 10 minutes for the full disk images. In this study, for operational GK-2A/AMI sea surface temperature (SST) retrieval, we developed SST algorithm using 8.7, 10.5, 11.2, and 12.3 \u03bcm channel data of Himawari-8/AHI as proxy data. In addition to cloud mask using the cloud detection algorithm, a quality control process of the estimated SSTs using real-time radiative transfer model data and climatology data was also applied for stable and accurate SST retrieval. The estimated SST is compared with the quality controlled GTS buoy temperature observation data. The daily, 5-day and 10-day SST composite data were produced based on the simple average method. In addition, daily blended SST composite data are also produced using retrieved Himawari-8 SST data, NOAA/AVHRR local area coverage data, microwave SST data from AMSR2 and GMI, drifter temperature data, and in-situ moored- buoy temperature data. Preliminary results of SST estimation from GK-2A data are presented. Algorithm Assessment and Error Characteristics STATUS OF ALGORITHM DEVELOPMENT FOR SEA SURFACE TEMPERATURE RETRIEVAL OF GEO-KOMPSAT-2A/ADVANCED METEOROLOGICAL IMAGER Summary and Conclusion \u2022 The GK-2A/AMI SST is basically retrieved using the multi-band (4 band) SST retrieval algorithm by default, and can be retrieved using the empirical regression SST algorithm and the hybrid SST algorithm optionally, depending on user demand. The retrieved SST does not represent the skin temperature; instead, it represents the temperature at a depth of approximately 20 cm, because the drifter data are used as in situ data. Therefore, it is reasonable that this retrieved SST is considered as the temperature between the skin and subskin layer. \u2022 At thermal infrared (IR) wavelengths, the SST can be retrieved only under clear sky. The accuracy of the satellite SST measurement is limited by the accuracy of sensor radiances, the quality of cloud screening, and correction for the effects of atmospheric absorption and scattering and surface reflection in the retrieval algorithms. GK-2A/AMI SST Retrieval and Validation \u0001 Period 1st Aug 2016 ~ 31st July 2017 \u0001 Hybrid SST Positive bias (> 30oC) \u0001 Multi-band Positive bias (< 10oC) Fig. Comparison between (a) Hybrid SST and (b) Multi-band SST and in-situ measurements and distributions of (c) Hybrid SST and (d) Multi-band SST as a function of the in-situ SST. The color scale represent the percentage of the data. Fig. Time series of RMSE and bias of retrieved SSTs using static SST coefficients from 1 August 2016 to 31 July 2017. Algorithm Assessment using Proxy Data (Himawari-8/AHI) \u0001 Hybrid SST positive error (SZA <15o) \u0001 Multi-band SST SST error increase at the high SZA Fig. Spatial distribution of errors of (a) Hybrid SST and (b) Multi-band SST and distributions of (c) Hybrid SST and (d) Multi-band SST as a function of satellite zenith angle (SZA). Error Characteristics GK2A/AMI SST Retrieval GK-2A/AMI Himawari-8/AHI OSTIA Fig. An example of spatial distribution of retrieved SST from GK-2A/AMI data at 00:30 UTC on 1 April 2019. Comparison of GK-2A SST with ot", "label": "poster"}
{"text": "Faculty of Psychology and Neuroscience Fast quantitative T1-mapping at ultra-high field using inversion-recovery echo planar imaging Dimo Ivanov, Benedikt A Poser, Sriranga Kashyap, Martin Havlicek, and K\u00e2mil Uluda\u011f Maastricht Brain Imaging Center, Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Netherlands RESULTS/DISCUSSION \u2022 The generation of high-resolution distortion-matched quantitative T1 maps at 7 and 9.4 T using an optimized inversion-recovery EPI sequence is possible \u2022 Anatomical data that is geometrically identical to the functional data provides means to localize brain activations more accurately \u2022 M0 maps have proton density and T2 *-weighting and therefore offer complementary anatomical information especially in subcortical regions \u2022 The T1 values of grey and white matter increase at 9.4 in comparison to 7T \u2022 The inversion efficiency was at least 95% throughout the brains of all participants at 7T. At 9.4T comparable inversion efficiency was achieved in most of the brain except for regions around and inferior to the left basal ganglia. Parallel transmission[7] can be used to increase B1 in these areas \u2022 The presented approach allows high-resolution accurate quantitative T1 mapping in less than 6 minutes, which makes it also applicable for clinical studies, as changes in T1 have been linked to many neurological disorders \u2022 Further scan time reductions using simultaneous multi-slice techniques[8,9] are still possible INTRODUCTION \u2022 In a typical fMRI analysis, the results are displayed overlaid on an anatomical image \u2022 A good co-registration between the fMRI and anatomical data is essential to achieve accurate localization of function \u2022 The differing image properties (contrast, distortions) of both datasets pose a challenge for the registration and often lead to errors \u2022 Co-registration between functional and anatomical data is most important, but also most difficult, in high-resolution fMRI at ultra-high field (B0- and B1-inhomogeneities) \u2022 Ultra-high field (\u22657 T) offers fMRI substantial benefits due to increases in signal-to-noise ratio and specificity[1] \u2022 The problem with co-registration between anatomical and functional data can be circumvented by acquiring distortion-matched anatomical images using inversion-recovery EPI with identical readout parameters \u2022 We demonstrate the feasibility of the approach at both 7 and 9.4 Tesla, utilizing recent advances in methods for fast quantitative T1-mapping[2] References [1] Uluda\u011f et al. Neuroimage, 2009. 48:150-65 [2] Renvall et al. Proc. ISMRM, 2014. 22:4282 [3] Shajan et al. MRM, 2013 71:870-9 [4] Norris DG. J Magn Reson Imaging, 2000. 11:445-51 [5] Clare & Jezzard. MRM, 2001. 45:630-4 [6] Hurley et al. MRM, 2010. 63:51-8 [7] Bazin et al. Neuroimage, 2014. 93 Pt 2:201-9. [7] Grissom et al. MRM, 2006. 56:620-9; [8] Moeller et al. MRM, 2010. 63:1144-53 [9] Setsompop et al. MRM, 2012. 67:1210-24 CONCLUSION The approach presented delivers geometrically-matched reference for fMRI studies at ultra-high field and can be applied for tissue segmentation and brain morphometry. METHODS \u2022 7T and 9.4T Siemens scanners with 32-channel (Nova Medical) and 31- channel[3] head coils, respectively \u2022 Five healthy volunteers (28\u00b14 years old) participated after giving informed consent \u2022 The acquisition rapidly obtains several inversion times (TI) by placing EPI readouts following an inversion pulse and permuting the slice order each repetition[4,5] \u2022 The slice-order permutation was done stepping through several slices at a time according to the reordering scheme proposed in Renvall 2014[2] \u2022 The inversion was done using an optimized 10 ms tr-FOCI pulse[6], which achieves high inversion efficiency at ultra-high field despite B1- inhomogeneities and SAR constraints \u2022 Acquisition parameters: 1 mm3 isotropic resolution; TR/TIs/slices/step = 10 s/32/128/4; TE = 24 ms (7T) & 20 ms (9.4T); TA = 5 min 30 s \u2022 Quantitative M0, T1 and inversion eff", "label": "poster"}
{"text": "L = 1032 cm-2s-1 at 2 GeV Lpeak = 2*1031 cm-2s-1 at 1 GeV - DC \u2014 1218 hexagonal cells with sensitive wires. \u03c3p/p \u2014 1.5-4.5% for 200-1000 MeV/c, \u03c3dE/dx/dE/dx = 14%. - SC solenoid magnetic field 1.3 T. - LXe-calorimeter and CsI-calorimeter are in barrel part and BGO-calorimeter is in the end caps. - the vacuum pipe inside DC is made of 0.5 mm aluminum with 17 mm inner radius. - inner shell of the DC is made from CFRP and has 20 mm radius. Search for the decay \u03c9\u2192\u03b7e+e- in \u03b7\u2192\u03c0+\u03c0-\u03c00 decay mode with the CMD-3 detector Budker Institute of Nuclear Physics, Novosibirsk, Russia \u2014 V. Mishin, on behalf of CMD-3 collaboration Events selection Abstract A set of selection criteria has been elaborated using Monte-Carlo modeling simulation (MC) to extract the \u03c9\u2192\u03b7e+e- decay events. Using a data sample of 6 pb-1 collected in 3 central points in the energy range close to \u03c9-meson invariant mass the upper limit on the branching ratio of decay has been estimated: B(\u03c9\u2192\u03b7e+e-) < 5 \u2219 10-6, which does not contradict to the Vector Dominance Model (VDM) prediction: (2.0 \u2013 4.8) \u2219 10-6. Preliminary results, further plans Secondary selection criteria To start signal events selection one has to determine charge particles types. Charge particles types are defined using kineamtic property of the decay, by a spatial angle between their tracks. Two tracks are leptonic, if the spatial angle between them less than 1.5 radian. The efficiency of such separating algorithm is 60% approximately. Difference in e/\u03c0 ionization losses used as additional veto for selected events. Primary selection criteria These criteria have been used to extract the events with appropriate signature having good reconstructed tracks: 1. Transverse momentum is > 40 MeV / c; 2. Total momentum absolute value is < 470 MeV /c; 3. Minimal distance between every track and beam axis is < 1 cm; 4. A number of points on each track is > 10; 5. A track polar angle value is between 0,9 and \u03c0 - 0,9 radian; 6. 4 charged tracks in event; 7. The total track charge is equal to zero; 8. More than one photon in the signal event. To suppress main background coming from decay \u03c9\u2192\u03c0+\u03c0-\u03c00 with consequent \u03c00 Daliz decay \u03c00 \u2192e+e- \u03b3 one has to investigate \u03c9\u2192\u03b7e+e- kinematic properties. Two missing masses have been chosen to separate the signal events and main background. An event is the signal one in case if parameters matches corresponding regions. Deviation between the signal event parameters and corresponding Gauss curve means have to be less than 3 standard divergences. Additional feature of decays \u03c9\u2192\u03b7e+e- and \u03c9\u2192\u03c0+\u03c0-\u03c00 has been found in the dependence between \u03c0+\u03c0- and e+e- total momenta. This feature gives an extra oppotunity to separate signal and main background events, nevertheless, it also suppresses signal events by a half. However, this gives possibility to check, wether selected events are likely being the signal samples or not. Among all used experimental events 3 of them satisfied enumerated selection constraints. Only one of them has 2 photons, however, they are located in the region filled with dense background. Among all used experimental events 3 of them satisfied enumerated selection constraints. Only one of them has 2 photons, however, they are located in the region filled with dense background. Assuming all picked out events are background, the decay relative probability B(\u03c9\u2192\u03b7e+e-) upper limit has been estimated: B(\u03c9\u2192\u03b7e+e-) < 5 \u2219 10-6, which does not contradict corresponding VDM prediction (2.0 \u2013 4.8) \u2219 10-6. Now we are going to modify described selection conditions to take into account Initial State Radiation (ISR). To enhance results objectivity we are going to apply blind-analysis method. To use it one has to choose two independent variables which have sharp prominent peak for the signal and quite flat or monotonous for the background. These variables are presented above. Width of each variable has been measured and blind-box size has been determined (3\u03c3 for each variable). All events into area will ", "label": "poster"}
{"text": "HOMICIDE RATES IN BRAZILIAN STATE OF PIAU\u00cd: COMPARISON AMONG FOUR PERIODS: 1982-1990, 1991-1999, 2000-2008, AND 2009-2017. CONCLUSION: There was a significative increase in annual homicide rates over time, during period 1982- 2017, in PIAU\u00cd State, Brazil. A C Raimondi 1, A M Raimondi 2 1 Father Albino Integrated Colleges \u2013 Faculty of Medicine (FIPA - MEDICINE), Catanduva, S\u00e3o Paulo State \u2013 SP, Brazil; 2 AM Raimondi Medical Services Company, Ribeir\u00e3o Preto, S\u00e3o Paulo State \u2013 SP, Brazil . INTRODUCTION: The aim of this study is comparing the homicide rates of Brazilian State of PIAU\u00cd, among four different periods: 1982- 1990, 1991-1999, 2000-2008, and 2009-2017 . References: [1] Gomes, F. P. (2000). Curso de estat\u00edstica experimental. [2] Callegari-Jacques, S. M. (2009). Bioestat\u00edstica: princ\u00edpios e aplica\u00e7\u00f5es. Artmed Editora. [3] Raimondi, A. M. (2002). Dicion\u00e1rio fundamental de bioestat\u00edstica. AM Raimondi.. DATA ANALYSIS: Data were provided from Brazilian government. The period 1982 to 2017 was divided into four equal periods of nine years each: 1982-1990, 1991-1999, 2000-2008, and 2009-2017. The Annual Homicide Rate (AHR) of State of PIAU\u00cd was calculated: AHR = LN[(H/N)*105)] AHR = Annual Homicide Rate, LN = natural logarithm, H = number of homicides per each year of period, N = number of inhabitants in the State of PIAU\u00cd in respective year. One-factor ANOVA procedure was employed to study the effect of levels (periods) on AHR. After ANOVA, a Tukey\u2019s test (a\u22640.05) was employed to comparing pairs of means by period. Table 2. One-factor ANOVA results: comparing period means of AHR, State of PIAU\u00cd, Brazil. RESULTS: Table 1. Statistical summary of AHR in four periods, State of PIAU\u00cd, Brazil. PERIOD N MEAN STANDARD ERROR OF MEAN 1982-1990 9 1.50 0.07 1991-1999 9 1.47 0.05 2000-2008 9 2.39 0.05 2009-2017 9 2.85 0.08 D.F. MEAN SQUARE F P PERIOD 3 4.17 118.06 < 0.0001 ERROR 32 0.04 - - TOTAL 35 - - - PERIOD 1982-1990 1991-1999 2000-2008 2009-2017 1982-1990 - - 0.89 1.34 1991-1999 - - 0.92 1.38 2000-2008 - - - 0.46 2009-2017 - - - - Table3. Significative differences* of means (AHR) between periods. *Evaluated by Tukey\u2019s test (a\u22640.05).", "label": "poster"}
{"text": "1. Mendapatkan komitmen dan dukungan terhadap inisiatif kesehatan dalam bentuk kebijakan, personel, pendanaan, fasilitas, akomodasi, partisipasi dalam kegiatan, dan banyak bentuk lainnya, tergantung pada situasi dan upaya. 2. Adanya pemahaman atau pengenalan atas kesadaran 3. Adanya ketertarikan dan minat yang sama 4. Adanya keinginan dan kemauan atas kepedulian atau kesanggupan untuk membuat dan menerima perubahan 5. Adanya Tindakan/perbuatan/kegiatan yang berbasis bukti 6. Adanya kelanjutan yang diharapkan 1 2 3 4 5 6 Kasus 18-356 1. Kami menyerukan kepada semua dosen untuk membuat dan mengembangkan Program Pemberdayaan Mahasiswa (PPM) berbasis bukti untuk mencegah masalah kesehatan mental di pendidikan tinggi. 2. Selama ada program, perlu dibentuk pendampingan dan ruang konsultasi pada setiap kelompok dan kelas untuk memberikan dukungan menyeluruh kepada mahasiswa yang menjadi sasaran utama. 3. Selain itu, untuk menciptakan lingkungan pendidikan yang bebas dari masalah kesehatan mental, kami menyarankan untuk menyediakan pendidikan promosi kesehatan di berbagai bidang. 1 2 3 IMPLEMENTASI Hal ini dapat dilakukan melalui kerjasama dengan institusi di lingkungan PTS/PTN sebagai upaya awal untuk mendukung dan berkolaborasi dalam pencegahan permasalahan kesehatan jiwa di perguruan tinggi DUKUNGAN ORIENTASI ORIENTASI KEBERHASILAN PENCEGAHAN KESEHATAN MENTAL DI LINGKUNGAN PERGURUAN TINGGI SWASTA/NEGERI (PKMPTS/PTN) DI JAWA TENGAH, INDONESIA 2021 2045 Yang di Harapkan adalah Terjadinya Penurunan Kasus Kesehatan Mental, Bunuh Diri, Percobaan, Depresi dsb Ardiansyah Jumaedi Nasir | Sulistyawati Suyanto Tujuan Utama 10 Provinsi Dengan Kasus Bunuh Diri Dari Data Tersebut, Jawa Tengah, Indonesia Urutan Pertama Komitmen Bersama", "label": "poster"}
{"text": "Open Science Conference 2020 - Call for Poster Presentations Driving institutional change for open, responsible research and innovation Abstract Open Science (OS) and Responsible Research & Innovation (RRI) seek to achieve a cultural change in our research environment. We are moving forward, but still Open Science and RRI seem not yet widely implemented. There is a gap between the actual and the potential role of open responsible research. In an extensive literature review, we analyzed what trends drive Open Science and RRI forward and what barriers prevent their wide implementation in the current system. To name a selection of critical trends, hyper-competition, increasing staff mobility and pressure, shrinking research funds etc. influence research practices negatively. These trends oppose the values of democracy, quality, self-protection, sustainability, technological innovation etc. which are driving RRI and Open Science. In addition, a comparison of different sectors and national contexts showed that indeed the variation across sectors is substantial: The type of research and stakeholder relationships is very important for the performance of RRI and Open Science. In particular, it matters how established or novel these sectors are. Whereas the differences in national settings seem to be less important for RRI and OS implementation. Building on this analysis, we conducted four case studies to observe how to deal with these findings to allow and support institutional change. Four institutions, including three universities and one company, conducted co-creation experiments: They engaged various internal and external interest groups in the design and implementation of a research project, e.g. by organizing focus groups, conducting interviews etc. This effort led to a RRI-model for the company, a brand new responsible research center at one university and an advanced approach to the implementation of ethics policies at another university. The findings on how institutions need to change their organizational frameworks to allow better embedment of responsible research and enable enhanced values for the quadruple helix actors (academia, industry, policy makers & society) are currently summarized. The result of this three-year work is a guiding document with recommendations on how to initiate and foster institutional change. These guidelines are complemented by a set of online courses to support different interest groups from academia and industry in initiating open and responsible practices. These include, but are not limited to, an introduction to RRI, RRI in industry, public engagement and ethics. The poster will present the main findings of our analysis and highlight the mutual learnings from the co-creation experiments. It will also present and refer to the online courses and guideline document as useful resources for the community to initiate institutional change.", "label": "poster"}
{"text": "Komparative Analyse der Einschlusskriterien f\u00fcr Journal Blacklisten und Whitelisten Michaela Strinzel, Anna Severin, Matthias Egger und Katrin Milzow Schweizerischer Nationalfonds Hintergrund \u2022Journal Blacklisten (BL) und Whitelisten (WL) versuchen die Legitimit\u00e4t und Integrit\u00e4t wissenschaftlicher Fachzeitschriften zu bestimmen [1]. \u2022Mit wachsender Bedeutung sog. Predatory Journals sind sie f\u00fcr Forschende auf der Suche nach geeigneten Journals zu zentralen Konsultationsstellen geworden [2]. \u2022Obwohl ihre Objektivit\u00e4t und Reliabilit\u00e4t angezweifelt und dadurch ihr Nutzen in Frage gestellt wurde [3], sind die Listen bisher noch nicht systematisch analysiert worden. Ziel Systematischer Vergleich der Ein- schlusskriterien und Inhalte (Journals und Publisher) von Journal BL und WL: \u2022Um ihren Nutzen als Indikatoren von Legitimit\u00e4t und Integrit\u00e4t wissenschaftlicher Fachzeitschriften zu verstehen \u2022Um die Anspr\u00fcche an die Qualit\u00e4t und Legitimit\u00e4t wissenschaftlicher Fachzeitschriften aufzuzeigen und einzuordnen Methode Qualitative Kodierung und komparati- ve Analyse der 198 Kriterien von 2 BL (Beall\u2019s List und Cabell\u2019s Internatio- nal) und 2 WL (DOAJ und Cabell\u2019s International) auf 3 Ebenen: \u2022Gegenstand des Kriteriums: auf welchen Aspekt einer Fachzeitschrift bzw. Publikationspraktiken bezieht sich das Kriterium? \u2022Auskunftsfunktion des Kriteriums: gibt das Kriterium Auskunft \u00fcber (1) die Qualit\u00e4t, (2) die Transparenz, (3) die Legitimit\u00e4t oder (4) den Etablierungsgrad einer Fachzeitschrift? \u2022Veri\ufb01zierbarkeit des Kriteriums: wie leicht l\u00e4sst sich ein Kriterium veri\ufb01zieren? Vergleich der Inhalte der Lis- ten (Journals und Publishers) mit dem Jaro-Winkler Abstand und Darstellung der \u00dcberschneidungen in Form von Venn-Diagrammen. Ergebnisse Abbildung 1: Gegenstand der Kriterien Abbildung 2: Auskunftsfunktion der Kriterien Abbildung 3: \u00dcberschneidung der BL Beall\u2019s List of Publishers und der WL DOAJ Listen Transparenz Qualit\u00e4t Etablierungsgrad Legitimit\u00e4t BL 3 2.4 2.5 2.1 WL 3 2.4 2 1.7 Tabelle 1: Veri\ufb01zierbarkeit der Kriterien unterschiedlicher Auskunftsfunktion im Mittel (bewertet auf einer Skala von 1=schwierig bis 3=leicht) Kontaktinformationen \u2022Schweizerischer Nationalfonds: http://www.snf.ch \u2022E-Mail: michaela.strinzel@snf.ch Erl\u00e4uterung der Ergebnisse \u2022Gegenstand der Kriterien Bei BL liegt der Fokus auf Gesch\u00e4ftspraktiken und Qualit\u00e4tskontrolle von Journals; bei WL liegt der Fokus auf der Qualit\u00e4tskontrolle sowie Richtlinien und Bestimmungen von Journals \u2022Auskunftsfunktion der Kriterien BL: der gr\u00f6sste Anteil der Kriterien gibt Auskunft \u00fcber die Integrit\u00e4t und Legitimit\u00e4t von Journals WL: der gr\u00f6sste Anteil der Kriterien gibt Auskunft \u00fcber die Transparenz von Journals \u2022Veri\ufb01zierbarkeit der Kriterien Im Schnitt ist die Veri\ufb01zierbarkeit der Kriterien gegeben, wobei es Unterschiede zwischen Kriterien unterschiedlicher Auskunftsfunktionen gibt. \u2022Vergleich der Inhalte Die \u00dcberschneidung der Inhalte von BL und WL (hier anhand der Publisher in Beall\u2019s List und im DOAJ aufgezeigt) ist relativ gering Schlussfolgerung Methodologisch scheint die Klassi\ufb01zie- rung und Gewichtung der Kriterien m\u00f6glich. Inhaltlich, hinsichtlich des Ge- genstand eines Kriteriums sowie hin- sichtlich ihrer Auskunftsfunktion, er- g\u00e4nzen sich die Kriterien von BL und WL und scheinen somit unterschied- liche Zwecke zu erf\u00fcllen. Das spie- gelt sich auch in der geringen \u00dcber- schneidung der Inhalte der Listen wider. Die systematische Klassi\ufb01zierung der Kriterien kann dazu dienen ein Set an Kriterien f\u00fcr die gesamtheitliche Betrachtung der Qualit\u00e4t, Legitimit\u00e4t und Transparenz von Journals zu de\ufb01- nieren. Referenzen [1] Vence, T. (2017). On Blacklists and Whitelists. The Scientist. [2] Swauger, S. (2017). Open access, power, and privilege: A response to \u2019What I learned from predatory publishing.\u2019 College & Research Libraries 78:11. [3] Olivarez et al. (2018). Format Aside: Applying Beall\u2019s Criteria to Assess the Predatory Nature of both OA and Non-OA Library and Information Scie", "label": "poster"}
{"text": "Access to the tools & documentation: Widget Storybook: https://t.ly/Aad7- TS4NFDI repo: https://github.com/orgs/ts4nfdi/repositories TSS widgets repo: https://github.com/ts4nfdi/terminology-service-suite TS4NFDI: Harmonizing Terminology Services within NFDI Roman Baum1, Syphax Bouazouni2, Naouel Karam2, Oliver Koepler3, Pooya Oladazimi3, Julia Sasse1 1 ZB MED - Information Centre for Life Sciences; 2 Institut f\u00fcr Angewandte Informatik e.V. (InfAI); 3 TIB Leibniz Information Centre Goal: Terminology Services 4 NFDI (TS4NFDI) is a cross domain service for the provision, curation, development, harmonization and mapping of terminologies. It aims to facilitate consensus-building and interoperability of services across disciplines to achieve a shared knowledge representation and knowledge engineering framework. The service seeks to integrate and converge individual solutions into a standardized, interoperable, and sustainable Terminology Service Suite. Standardised, harmonised and interoperable access to Terminologies across all integrated Terminology Services, available for all NFDI-services via the Terminology Service Suite widgets or the API Gateway. 1 Interconnection of existing Terminology Services via a Service Wrapper. This allows for terminology use and management across disciplines, serving as a basis for terminology harmonisation efforts (Integration and Interoperability). 2 Javascript-based widgets that can be embedded in graphical user interfaces (UIs) to simplify UI development and visualization of semantic information in other NFDI services. This streamlines the process of integrating standard vocabularies and performing semantic annotation on data, as well as supporting the data discovery process. 5 SSSOM based Cross-domain Mapping Service to manage and provide mappings for terminologies as a central service. 3 Support of external terminology services as backbone is possible. 4 5 1 2 3 4 More information and contact details: Mail: ts4nfdi@lists.nfdi.de NFDI Rocket.Chat: https://all-chat.nfdi.de/ Channel: #ts4nfdi; join: https://all-chat.nfdi.de/channel/ts4nfdi About the project: https://terminology.services.base4nfdi.de/ Funded by DFG as part of NFDI. Grant Numbers: 521453681, 521460392, 521462155, 521463400, 521466146, 521471126, 521473512, 521474032, 521475185, 521476232 3rd Annual Conference 04.+ 05. Dec. 2024 KUBUS, Leipzig", "label": "poster"}
{"text": "ID #40; arXiv:2404.17559 amann16.iitr@gmail.com Investigating Quantum Decoherence in \u03bd-Oscillation at ESSnuSB Experiment Author: Aman Gupta 1,2; Presenter: Monojit Ghosh 3 on behalf of the ESSnuSB collaboration 1Saha Institute of Nuclear Physics,Kolkata, India, 2HBNI,Mumbai, India,3Ru\u0111er Bo\u0161kovi\u0107 Institute,Zagreb, Croatia Introduction \u2022Neutrino oscillation is a quantum mechanical phenomenon that arises due to the coherent superposition of neutrino mass states. However, if neutrino as a quantum system is coupled to an environment, the coherence between two or more propagating states may be lost leading to the suppression of flavour oscillations. \u2022Such type of environmentally induced quantum decoherence (QD) in neutrino states might emerge from quantum gravity effects or space-time \u201cfoam\u201d which acts as dissipative sources and can modify the \u03bd-oscillation probability in various ways [1]. QD: Formalism The time evolution of neutrinos in an open quantum system is given by \u2202\u03c1(t) \u2202t = \u2212i[H, \u03c1(t)] + D[\u03c1(t)] , (1) where H is the neutrino Hamilto- nian which can be written as H = 1 2E \uf8ee \uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8ef\uf8f0 U \uf8eb \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ed 0 0 0 0 \u2206m2 21 0 0 0 \u2206m2 31 \uf8f6 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f8 U\u2020 \uf8f9 \uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fa\uf8fb + VCC \uf8eb \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ec \uf8ed 1 0 0 0 0 0 0 0 0 \uf8f6 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f7 \uf8f8 . (2) The effect of decoherence is given by the dissipator matrix D which on imposing relevant physical con- ditions can be parametrized as D = \u2212diag(\u039321, \u039321, 0, \u039331, \u039331, \u039332, \u039332, 0) . (3) The solution to the Eq.1 is given by \u03c1\u03b1 ij(x) = \u02dcU\u2217 \u03b1i \u02dcU\u03b1je\u2212(\u0393ij+i \u02dc\u2206ij)x (4) and the oscillation probabilities in the presence of decoherence read as P(\u03bd\u03b1 \u2192\u03bd\u03b2) = Tr \uf8ee \uf8ef\uf8ef\uf8f0\u03c1\u03b1(0)\u03c1\u03b2(x) \uf8f9 \uf8fa\uf8fa\uf8fb (5) Here, \u02dcU is the modified PMNS ma- trix in matter and \u02dc\u2206ij = \u2206\u02dcm2 ijL 4E , with \u2206\u02dcm2 ij being the mass squared differences in matter. \u2022L = 360 km, Water Cherenkov detector of fiducial volume 538 kt and 5 years run-time of neutrino + 5 years of antineutrino [2]. Oscillation Probability including Decoherence P(\u03bd\u03b1 \u2192\u03bd\u03b2) = \u03b4\u03b1\u03b2 \u22122 X i>j Re \" \u02dcU\u2217 \u03b1i \u02dcU\u03b2i \u02dcU\u03b2j \u02dcU\u2217 \u03b2j # \uf8ee \uf8f01 \u2212cos \uf8eb \uf8ed2 \u02dc\u2206ij \uf8f6 \uf8f8e\u2212\u0393ijL \uf8f9 \uf8fb+ 2 X i>j Im \" \u02dcU\u2217 \u03b1k \u02dcU\u03b2k \u02dcU\u03b2j \u02dcU\u2217 \u03b2j # sin \uf8eb \uf8ed2 \u02dc\u2206ij \uf8f6 \uf8f8e\u2212\u0393ijL , QD induces terms similar to damping phenomena of the form e\u2212\u0393ijL in the oscillation probability. Fig.: Effect of \u039321 and \u039332 on the appearance probability for the ESSnuSB. \u2022The P\u00b5e probability is mostly affected by \u039321 in comparison to \u039332. \u2022The effect of \u039321 is significant when \u03b4CP is \u221290\u25e6. Important Analytical Formulae For maximal CPV, the relevant contributing terms for \u039321 and \u039332 are |P CP\u2212odd \u00b5e | \u221d|2\u03b1\u220631(\u039321L \u22122 sin2 \u220631) \u2212\u039321L sin 2\u220631| . |P CP\u2212odd \u00b5e | \u221d|\u039332L cos 2\u220631 + 2 sin2 \u220631| . For \u03b4CP = 0, 180\u25e6, expression for CPV precision is given by: \u2206\u03b4CP \u221d 1 |2\u03b1\u220631(\u039321L \u22122 sin2 \u220631) \u2212\u039321L sin 2\u220631| ; 1 |\u03b1\u220631\u039332L cos 2\u220631 + 2\u03b1\u220631 sin2 \u220631| . On the other hand, for maximal CP violation, we obtain \u2206\u03b4CP \u221d 1 |\u039321L(cos 2\u220631 + cos 2\u03b812) + 2\u03b1\u220631 sin 2\u220631| ; 1 |\u03b1\u220631(1 \u2212\u039332L) sin \u220631| . Bounds on \u039321 and \u039332 Other experimental bounds at 90% C.L. are [3, 4] \u039332 = \u039321 < 9.4 \u00d7 10\u221224 GeV [MINOS/MINOS+], \u039321 < 1.2 \u00d7 10\u221223 GeV [DUNE], \u039332 < 4.7 \u00d7 10\u221224 GeV [DUNE] . CPV Sensitivity & Precision 24.0 23.5 23.0 22.5 22.0 21.5 21.0 log10 0.0 2.5 5.0 7.5 10.0 12.5 15.0 17.5 20.0 2 (CPV) solid: true CP = + 90\u00b0 dashed: true CP = 90\u00b0 21 when 32 = 0 32 when 21 = 0 21 = 32 For small \u039321, the sensitivity first slightly decreases and when the de- coherence term becomes dominant, the relevant probability increases along with \u039321, improving the sen- sitivity. 24.0 23.5 23.0 22.5 22.0 21.5 21.0 log10 0 1 2 3 4 5 6 7 8 CP[in deg.] solid: 21 when 32 = 0 dashed: 32 when 21 = 0 dot dashed: 32 = 21 true CP = 0\u00b0 true CP = 180\u00b0 24.0 23.5 23.0 22.5 22.0 21.5 21.0 log10 0.0 2.5 5.0 7.5 10.0 12.5 15.0 17.5 20.0 CP[in deg.] solid: 21 when 32 = 0 dashed: 32 when 21 = 0 dot dashed: 32 = 21 true CP = + 90\u00b0 true CP = 90\u00b0 2.24 cm Correlations Key Takeaways \u2022For the first time, we explore the sensitivity of ESSnuSB to const", "label": "poster"}
{"text": "C How much am I exposed? Exploring public perceptions of EMF exposure from mobile communication technology and 5G B32 FB01 Sarah Link1, Marie Eggeling1, Ferdinand Abacioglu1, Christoph B\u00f6hmert1 1IU International University of Applied Sciences A B D E1 E2 F1 F2 G H I1 I2 RESULTS: Base Station Siting \uf0b7Initially, most participants (n=32) chose a location outside the village (locations 1, 3, 5, 6) \uf0b7A relative majority of participants (n=16) selected location 3 on the factory building \uf0b7Arguments for the initial choice: \uf0b7Distance from the reference point (n=13) \uf0b7Aesthetic aspects (n=12) \uf0b7Reception (n=8) \uf0b7Radiation only played a role in the choice of location for three participants \uf0b7After informing participants that for regular MP users individual exposure increases with increasing distance to a BS, about half (n=8) of those initially choosing a remote site (locations 5/6) changed to a location closer to the reference point. \u201cI would then perhaps change to location 3. Well, [...] I didn't know that the transmission power would be correspondingly higher.\u201d (male, 42, city) RESEARCH AIMS 1st Aim: Investigate in which situations lay people feel particularly exposed to EMFs emitted by MC/5G. 2nd Aim: Learn about people\u2019s preferences for the siting of 5G emitting base stations, and about the reasons for these preferences. RESULTS: Exposure Perception \uf0b7Situations in which BSs were central were associated by 20 participants with a higher personal exposure than the mobile phone (MP) situations \uf0aeAs reasons for their assessment participants referred to the BS as \u201cabstract\u201d, \u201cthe common enemy\u201d, \u201chostile\u201d or \u201cugly\u201d. The MP, on the contrary, was perceived as \u201ckind\u201d, \u201cfamiliar\u201d or \u201csomething one enjoys\u201d. \uf0b7A higher number of BS antennas was associated with a higher exposure \uf0b7For MPs 10 participants associated a higher number of distant devices with a higher exposure level than one close device \uf0b7The closer the mobile device is to sensitive body parts (head, reproductive organs), the higher the situation tended to be ranked \uf0ae23 participants ranked at least one of the situations (phone call, phone in pocket) prior to an other MP situation \uf0b7For BS EP, participants tended to rank the 5G prior to the 4G situation (n=21) \uf0b7No relevant difference between Wi-fi, 4G, and 5G situations regarding MP EP Lay People\u2019s Exposure Perception Quantity Data transfer Antenna vs. Phone Proximity to particular body parts Distance Duration Visibility Location Network type Change 4G 5G METHODS \uf0b7Structure: 35 individual interviews + 6 focus groups \uf0b7Sample: 18f/17m, mean age: 39y (range 18-67y) \uf0b7Variables assessed: sociodemographic variables, exposure perception (EP), base station (BS) siting preferences, further variables (see handout) Interactive tasks: \uf0b7Ranking task: Participants had to rank situations (see fig. 2) according to their EP \uf0b7Base station siting task: Participants had to select a BS site in a fictious scenario (see fig. 3) CONCLUSION \uf0b7Exposure to EMF is a subordinate factor influencing site selection and negative attitudes towards BS \uf0b7No evidence that 5G is evaluated / perceived significantly different than previous MC standards CONTACT Sarah Link, sarah.link@iu.org DISCUSSION \uf0b7Siting preferences are influenced by many factors \uf0b7EP depends on a variety of factors \uf0aesimilar to other EMF sources (e. g., power lines) \uf0b7Dimensions and EP \uf0b7EP is higher for BS than for MP \uf0b7Proximity and quantity play a rather important role \uf0b7Network type seems to be irrelevant for MP EP Limitations: \uf0b7No complete variation of dimensions within the situations \uf0aeDifficult to attribute EP / results of the ranking task to a single criterion (such as 5G reception) \uf0b7Site selection partly in the interest of multiple stakeholders (not only related to reference point) Findings will be used to implement a quantitative online survey in multiple European countries Figure 1: Dimensions possibly affecting exposure perception Figure 2: Exposure situations used in the ranking task Figure 3: Results of the ", "label": "poster"}
{"text": "\uf0e0https://webappsx.ugent.be/eventManager/events/DigitisingtheHumanitiesPleaseregisterhere \uf0e0Contactjulie.birkholz@ugent.beannemieke.romein@ugent.bettps://www.ghentcdh.ugent.be/dhresearchlabUniversiteitGent@ugent; @ghentcdhBringing transcriptions together \u2013Transcription Network BE/NLThisjoint effort fromDutch and Belgium institionsis (soontobe) launchedtogathertranscriptionsand photo\u2019sof archivalmaterialin Dutch. These couldbeusedtocreatemore genericmodelstobeabletodecyphertextsmore quicklyor buildmodelsforspecificeras. Ifyouhappen tohave or knowpeoplewhohave transcriptionsin Dutch fromanyperiod, do nothesitatetocontact Annemieke whocaninformyoufurther. The Dutch National Archivewillsupport thisproject witha part-timecoordinatorthatwillassist withfaciliatingtheuseof automatic transcritpionsoftwaresand platforms foranyresearch usingDutch languagemanuscripts. Workshops and training willalsobecoordinatedthroughtheDutch National Archive.The Scantentis a useful aid to scan documents with your phone (especially with the Android DocScan-app)", "label": "poster"}
{"text": "Sum Rear Tire Front Tire Lat. Acc + Yaw Rate Roll Acc. Roll Rate unstable stable Analysis of High speed instability of Weave Mode in Motorcycle by Using Energy Flow Method Hirotaka TAMOTO1, Tetsuya KIMURA1, Masayuki MIKI1, Tsuyoshi KATAYAMA2 1Fundamental Technology Research Division, YAMAHA MOTOR CO., LTD. Shizuoka, Japan 2New Mongol Institute of Technology, Ulaanbaatar, Mongolia Bicycle and Motorcycle Dynamics 2019 Symposium on the Dynamics and Control of Single Track Vehicles, 9 \u2013 11 September 2019, University of Padova, Italy Degree of freedom in weave mode Real part of eigenvalue \u221d1/m Imaginary part of eigenvalue \u221d1/\u221am Characteristics of damped vibration system Equation of motion m \ud835\udc99+ \ud835\udc84 \ud835\udc99+ \ud835\udc8c\ud835\udc99= \ud835\udfce m \ud835\udc84 \ud835\udc8c Eigenvalue \ud835\udf40= \u2212\ud835\udc84\u00b1 \ud835\udc84\ud835\udfd0\u2212\ud835\udfd2\ud835\udc8e\ud835\udc8c \ud835\udfd0\ud835\udc8e Given the vibration system with one degree of freedom, Which degree of freedom is the weave mode? X Component : Proportional to real part of eigenvalue Y Component : Proportional to imaginary part of eigenvalue Eigenvector \u00d7Coefficient \ud835\udc4b= \ud835\udc66 \ud835\udf13 \ud835\udf19 \ud835\udeff \ud835\udc4c\ud835\udc53 \ud835\udc4c\ud835\udc5f Eigenvectors normalized with yaw rate (Mf k2 +Irz + Ifx sin2\u03b5+ Ifz cos2\u03b5) \ud835\udf13= - Mf k \ud835\udc661 -\uff5bMf jk-Crxz + (Ifz-Ifx)sin\u03b5cos\u03b5\uff5d \ud835\udf11 -(Mf ek+Ifz cos\u03b5) \ud835\udeff+\uff5bify/Rf+(iry+\u03bbi)/Rr\uff5d \ud835\udc651 \ud835\udf11 - Mf k \ud835\udc651 \ud835\udf13+ ify/Rf sin\u03b5 \ud835\udc651 \ud835\udeff+ l1 Yf \u2013l2 Yr Yaw system equation Unit vector of yaw rate The contribution to the stable direction of Sum \u21d2Larger at 120km/h than at 200km/h Damping ratio (Real part) Frequency (Imaginary part) Only the Yaw system almost matches ! Main freedom of weave mode is Yaw system m \ud835\udc99= \u2212\ud835\udc84 \ud835\udc99\u2212\ud835\udc8c\ud835\udc99 \u00d71.1 \uf0fcRear tire force that most affects the stability of the weave mode. \uf0fcThe main reason why the rear tire force decreases is a phase delay. \uf0fcCause of the phase delay is the decrease of the Yaw Rate coefficient. \uf0fcMain factor of the decrease in the Yaw rate coefficient is the increase in the vehicle speed. X-component divided Into Tire and Body X-component divided into Front tire and Rear tire \u3010Analysis using the Yaw system equation\u3011 \u3010Analysis using the Rear tire equation\u3011 The change of Phase and Magnitude Sum Yaw Rate Lat. Velo. unstable stable The cause is CYs2 or \ud835\udc991 120km/h 200km/h Rate of change [%] 120.00 200.00 166.67 3.34E+03 3.65E+03 109.07 \ud835\udc99 1 CYs2 \u203bl2 is unchanged Change rate of CYs2 and \ud835\udc991 Main factor! Yr = \uff0dCYs2/ \ud835\udc651 \ud835\udc661 \uff0bCYs2l2/ \ud835\udc651 \ud835\udf13\uff0bCYc2\u03c6 Rear tire equation Lat. Velo. Yaw Rate Roll Angle Main cause Energy Flow Method (EFM) Analysis result Summary Introduction In this report, we investigate the cause of the decrease in the stability of weave mode in high speed region using Energy Flow Method. Rear tire gives most influence on the weave mode In Front and Rear tire, the ratio of Rear tire is larger The main factor determining stability is Energy Flow of tire Most of the breakdown of change is the delay in the Phase of the Rear tire Yaw Rate \u21d2Reduction of coefficient Main factor of the decrease in the Yaw rate coefficient is the increase in the vehicle speed", "label": "poster"}
{"text": "An efficient, tunable solution for pre-capture multiplexing in targeted sequencing via novel chemistry and semiconductor DNA synthesis technology Irene Song, Raymond Miller, Jiashi Wang, Jianpeng Wang, Long Fan, Lumeng Ye, Hong Li, Heidi Huang Oligo Department, GenScript USA Inc., 860 Centennial Ave., Piscataway, NJ 08854 GenScript Tunable target enrichment by semiconductor technology GenScript CMOS Semiconductor electrochemistry T T T T TT T T T T TT Deprotected Amidite Electrochemical deblocking Electrode activated Electrolyte Solution Acidic Environment T T T T TT T T T T T T AAAAAA A A A A A A A Amidite Solution Coupling T T T T T T T T T T TT AAAAAA Wash Figure 3. GenScript used Semiconductor DNA Synthesis platform a) GenScript-CustomArray CMOS semiconductor chip b) Electrochemical synthesis of DNA oligo in transient micro-reactors c) NGS analysis concludes 99.7% coverage. Interdecile # < 2.5 Semiconductor technology offers a fast and cost-effective way to synthesize capture probes panel for target enrichment. Moreover, since the sequence and abundance of each probe on the chip can be precisely controlled, the panel performance can be evolved based on NGS data feedback. Figure 4. Comparison of semi-conductor based dsDNA hybridization probe panel with column-based ssDNA probe panel. ~8000 120nt probes covering a 600kb target region. Figure 5. Comparison of different technology. Semiconductor chip synthesized GenFisher custom hybridization probes panel provides better capture efficiency compared to other vendors\u2019 panels using single-stranded DNA, RNA or inkjet synthesized double-stranded DNA. All data are average of two independent technical replicates. a b c Simplified pre-capture target enrichment workflow with TRUE Universal blockers 0% 20% 40% 60% 80% 6nt 8nt 10nt On Target Rate Universal Blocker Performance Universal blockers by novel chemistry To enable the maximum pooling potential of targeted NGS libraries, here we introduce a novel design and chemistry to hybrid capture blockers, an essential component in the experimental workflow to block the permissive interactions between library adapters and target probes, and adapters themselves, both of which lead to wasteful sequencing. The conventional blockers, whose sample index-matching portion uses either degenerate bases or universal pairing bases, depends on the length of the sample index for the libraries, dramatically impeding the flexibility of index-blockers pairing. Our new invention, GenFisher Universal Blockers, create a novel solution to the annealing between sample indexes on libraries and blockers regardless of the index length. Figure 6. GenFisher Universal blocker makes pre-capture pool easier a)GenFisher Universal Blocker uses novel chemistry to block indexes of different lengths. b)Hybridization capture by GenFisher Hybridization kit and Universal Blockers show similar on target rate regardless of index length c)1-plex vs 8-plex pre-capture pooling with and without Universal Blockers. Multiplexing has no effect on the efficiency of blockers. a) b) c) www.genscript.com 860 Centennial Ave., Piscataway, NJ 08854, USA Toll-Free: 1-877-436-7274 Telephone: 1-732-885-9188 Fax: 1-732-210-0262 Email: Irene.Song@genscript.com Figure 1. GenFisher 16hr Hybridization kit is compatible with both dsDNA probe and ssDNA probes. 1hr fast hybridization kit allows 1 day workflow for library preparation and target enrichment without compromising capture efficiency. All data without considering flanking regions when calculating on-target %. 50.00% 52.00% 54.00% 56.00% 58.00% 60.00% 62.00% 8-plex 12-plex 16-plex 24-plex Pre-capture pooling with GenFisher hybridization kit On target base % 56.1% 49.5% 36.7% 66.0% 66.6% 55.5% 0.0% 20.0% 40.0% 60.0% 80.0% Competitor W Competitor X Competitor Y GenScript Competitor Z GenFisher Hybridization kit 16hr On target base % High compatibility hybridization and wash kit with 24-plex pre-capture pooling Figure 2. GenFisher Hybridization kit", "label": "poster"}
{"text": "II Poster No. A-5 National Aeronautics and Space Administration Jet Propulsion Laboratory California Institute of Technology Pasadena, California www.nasa.gov Copyright 2015. All rights reserved. National Aeronautics and Space Administration Herschel Galactic plane survey of ionized gas traced by [NII] [ ] plays a significant role in star formation as it is produced only in ionized regions; in HII regions as well as diffuse ionized gas. The ionization potential of nitrogen (14.5 eV) is greater than that of hydrogen (13.6 eV), and carbon (11.3 eV), therefore the ionized nitrogen [NII] lines reflect the effects of massive stars, with possible enhancement from X-ray and shock heating from the surroundings. Motivation Results [NII] has two fine structure transitions at 122 and 205 \u00b5m. The two lines can be used to calculate the electron density and column density of N+, if one assumes that the emission from both transitions originate in the same gas and under roughly uniform conditions. [NII] detections are mainly toward the Galactic center. [NII] electron densities are found to be between 10 to 50 cm-3 (Fig. 2) and N+ column densities range between 1016 to 1017 cm-2. High densities indicate that the source of the emission is not the WIM (Warm Ionized Medium), which has densities 10-100 times smaller. Far infrared and sub-/millimeter atomic & ionic fine structure and molecular rotational lines are powerful tracers of star formation. Although CO lines trace cool to moderately warm molecular gas, ionized carbon [CII] produces the strongest lines, which arise from almost all warm (T >35 K) parts of the ISM. However,[CII] alone cannot distinguish fully ionized gas from weakly ionized gas. Methods Two far-infrared 122 \u00b5m and 205 \u00b5m [NII] fine structure spectral lines are observed via Photodetector Array Camera and Spectrometer (PACS) onboard Herschel Space Observatory. The sample consists of 149 lines-of- sight (LoS) positions in the Galactic plane, following those of the [CII] 158 \u00b5m observations obtained with the GOT C+ survey. PACS data have 5x5 spatial pixels therefore all 25 spectra are averaged to improve S/N, and that led to increase the number of detections in the averaged spectra. [CII] is the most important coolant of atomic hydrogen clouds and the photon dominated regions (PDRs) of molecular clouds and is widely used as a tracer of star formation. We found that [NII] measured with HIFI as well as PACS are linearly correlated with the [CII] emission. Fig 3: Position vs. intensities of [NII] and [CII] are shown through the Galactic plane. Fig 4: [NII] vs [CII] intensities shows tight correlation. Fig 2: Electron densities are shown as function of the position in the Galactic Plane. Galactic longitude (l) log I (W m-2 sr-1) # of LoS Int Ratio n(e) = 100 cm-3 n(e) = 50 cm-3 n(e) = 10 cm-3 n(e) = 1 cm-3 [NII] Fig 1: Histogram of intensities [NII] emission is highly correlated with that of [CII], implying that between 1/3 and 1/2 of the [CII] emission arises in the ionized gas. Possible origin of the observed [NII] include the ionized surfaces of dense atomic and molecular clouds, the extended low density envelopes of HII regions, and low-filling factor high-density fluctuations of the WIM. The pixel to pixel variation of the emission within a single Herschel pointing is relatively small, which is interpreted as the [NII] emission comes from an extended gas. N [NII] detections are mainly toward the Galactic center (intensity distribution shown in Fig. 1), but the opposite side of the Galactic center gives upper limits of ~4x10-10 W/m2/sr-1 for the 122 \u00b5m line and ~2x10-9 W/m2/sr-1 for the 205 \u00b5m line (Fig. 3). Principal Investigator: Umut Yildiz (3266) Paul Goldsmith (3266), William Langer (3200), Jorge Pineda (3266) It is important to quantify what fraction of [CII] emission arises in the ionized gas, to resolve the different parts of the ISM, leading to determine the total mass of the ISM.", "label": "poster"}
{"text": "Conclusion Outlook Introduction In materials science, the understanding of new materials is becoming increasingly complex. Without suitable data managing concepts, it will no longer be possible to handle the constantly growing amounts of data generated from simulations and experiments. The Karlsruhe Data Infrastructure for Materials Science (Kadi4Mat)[1] therefore presents a research data infrastructure that aims to resolve these challenges while taking the FAIR data principles[2]into account. Its functionalities can be summarised as a repository and an electronic lab notebook. Kadi4Mat Functionalities Kadi4Mat presents an ecosystem that encompasses different modules \u2013Repository,Electronic Lab Notebook,Workflows,Ontologies, Machine Learning\u2013 which in sum create a FAIR research data infrastructure. Through its REST-API Kadi4Mat further offers defined interfaces for connecting it to other systems, allowing for the simple extension of the available functionalities. lars.griem@kit.edu www.iam.kit.edu/cms References [1] Brandt, Nico et al. Data Science Journal, vol. 20, 2021, p. 8. [2] Griem, L, et al. Data Science Journal, vol. 21, 2022, p. 16. [3] Sangya Pundir / CC BY-SA 4.0 KIT \u2013 The Research University in the Helmholtz Association Automated Documentation of Research Processes Using RDM L. Griem 1, R. Thelen2, M. Selzer 1 1Institute of Nanotechnology (INT-MSS), Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany 2Institute of Microstructure Technology, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany Ecosystem Micro gear Job ticket Green job ticket Batch number: 04552 602 Editor: see above Page: 1 of 2 IFA-Number: 11-935F-01F Provided parts, masks etc.: Manufacturing item: Object number: 05841 See FS02 Micro gear for demonstration Customer: Mustermann lfd.- Production process Speci\ufb01cations Amount Finished No. Production & test steps (e.g. AA, PA, Text etc.) in out Name, Date 1. Create job ticket and folder AA605.xx --- --- (MF-FVB) 2. Obtain job ticket and all provided parts AA605.xx (GL-FAF) 3. Take substrates of type SP403009.xx for the batch numbers: 1.) Batch No.:__________________ 2.) Batch No.:__________________ 3.) Batch No.:__________________ 4.) Batch No.:__________________ from the clean room storage and mark the wafer box. AA619.xx 4 4. Vapour deposition of metallic layers. AA653.xx Cr-Thickness: 5nm Au-Thickness: 15nm Current Documentation Implementation Automated Documentation The FAIR management of research data is undoubtedly an important step in accelerating scienti\ufb01c work. However, a signi\ufb01cant part of knowledge often lies not in the research data itself, but in the processes that led to its creation. Therefore, the research data infrastructure Kadi4Mat [1] provides, in addition to a data repository, a work\ufb02ow editor [2] for process documentation and automisation. In combination, these modules allow the automated and FAIR documentation of scienti\ufb01c processes and the data generated within them. The implementation of such an automated documentation is illustrated through the example of the experimental production of microstructural components at the Institute of Microstructure Technology of the KIT. Introduction Conclusion Integrating the job ticket documentation into the research data infrastructure Kadi4Mat offers many bene\ufb01ts. The job tickets can be quickly searched for speci\ufb01c parameters, equipment or processing facilitating the development of new production processes. Additionally, the user is interactively guided through the manufacturing process in the work\ufb02ows. This not only ensures quality assurance but also helps new unexperienced employees to produce components e\ufb03ciently. Main Takeaway The Kadi4Mat ecosystem offers the possibility to store and structure data and automise their documentation.This makes FAIR data handling effortless in everday research. KadiWeb Structured data management and exc", "label": "poster"}
{"text": "Archivieren am Data Center for the Humanities der Universit\u00e4t zu K\u00f6ln Kontakt: info-dch@uni-koeln.de https://dch.phil-fak.uni-koeln.de CC-BY 4.0 Anke Debbeler (Camunda BPMN 2.0 Dia- gramm, Text), Felix Rau (Text), Elisabeth Mollenhauer (Lay- out) Stand: August 2024 (Version 1.0.0) https://doi.org/10.5281/zenodo.13375261 LAC DATA & METADATA CONVERSION PIPELINE Das Diagramm dokumentiert formal den Konvertierungsprozess, den Daten und Metadaten nach der \u00dcbergabe w\u00e4hrend der Ge- nerierung des Archival Information Package (AIP) durchlaufen, bevor sie ins LAC \u00fcberf\u00fchrt und publiziert werden. Zur Daten\u00fcbergabe gibt es mehrere Optionen: Diese h\u00e4ngen von der Datengr\u00f6\u00dfe und dem Zugang der Datengeber*innen zum Cloud-Service Sciebo ab, der vom DCH verwendet wird. Das LAC nutzt das Pro\ufb01 l Basic Language Archive Metadata (BLAM) des ISO 24622-Standards Component Metadata Infrastructure (CMDI). Die Datengeber*innen liefern die Metadaten in einem auf das LAC angepasste Excel Sheet, das im Rahmen der AIP- Generierung in dieses Pro\ufb01 l \u00fcberf\u00fchrt wird. Die Architektur des LAC basiert auf dem Oxford Common File Layout (OCFL), f\u00fcr dessen Anforderungen die Ordnerstruktur der \u00fcberreichten Daten angepasst werden muss: Eine f\u00fcr das LAC spezi\ufb01 sche Besonderheit ist hierbei die Unterteilung eines Datensatzes (Collection) in mehrere Bundles. Ein Bundle ist in der Regel \u00e4quivalent zu einer Aufnahme(session), zu der jeweils eine Medien- und eine Annotationsdatei zugeordnet werden. Die Datengeber*innen haben die M\u00f6glichkeit, der Collection bzw. den Bundles zus\u00e4tzliche Metadatendateien hinzuzuf\u00fcgen. Die Generierung des AIP ist Teil des LAC Depositing Workflow, dessen formale Dokumentation hier einsehbar ist: https://doi.org/10.5281/zenodo.13375243. Das Data Center for the Humanities (DCH) bietet \u00fcber das Language Archive Cologne (LAC) die Sicherung und Publi- kation audiovisueller Daten an. Im Sinne der FAIR-Prinzipien (Findable, Accessible, Interoperable, Reusable) stellt das LAC einen offenen, webbasierten Zugang zu hochwertigen digitalen Sprachressourcen zur Verf\u00fcgung. Als ein mit dem CoreTrustSeal (CTS) zerti\ufb01 ziertes Reposito- rium innerhalb der europ\u00e4ischen Common Language Resources and Technology Infrastructure (CLARIN) arbeitet das LAC nach dokumentierten Arbeitsprozessen, die Qualit\u00e4t und Integrit\u00e4t von Daten und Metadaten sichern.", "label": "poster"}
{"text": "Case study Climate Change : How Earth System Science benefits from FAIRCORE4EOSC components Anna-Lena Fl\u00fcgel1, Heinrich Widmann1, Beate Kr\u00fcss1, Hannes Thiemann1, Stephan Kindermann1 , Fanny Adloff1 EGU General Assembly 2024, Vienna, Austria The European Open Science Cloud (EOSC) is an ecosystem of federated research data and services, and an open science infrastructure. FAIRCORE4EOSC (FC4E) supports a FAIR EOSC by developing nine new core components improving cross-domain interoperability. Challenges \u25cfEOSC services need to be cost-effective, scalable, reliable, trustworthy and sustainable long-term \u25cfRequired adaption on ENES side to offer customized and easy-to-use services \u25cfTechnical incompatibilities due to different technologies and standards Requirements of Case Study \u2018Climate Change\u2019 Five thematic case studies drive the development of the FAIRCORE4EOSC (FC4E) technical components. DKRZ1 specifies the user requirements for the case study \u2018Climate Change\u2019 and works with the FC4E developers on the integration of several components into ENES RI. RAiDs (Research Activity identifiers) are being assigned to the CMIP6 project, providing an aggregated view on related entities (data provenance, software, people involved, etc). PIDGraph assigns DOIs to different aggregation levels of CMIP6 data, connects DOIs and RAiDs, links data collection metadata and makes it findable within the RD Graph. The EOSC RDGraph (Research Discovery Graph) enables advanced and cross domain data discovery and access for the ENES community and researchers from other scientific areas. MSCR (Metadata Schema Crosswalk Registry) improves cross-domain reuse of ENES data by mapping climate variable vocabularies to other ontologies. DTR (Data Type Registry) defines and registers standardized simple and complex data types and thus enhances machine actionability. 1 German Climate Computing Center (DKRZ, https://www.dkrz.de) Integration of FAIRCORE4EOSC components into ENES-RI Services Benefits \u25cfimproved interoperability and traceability of research activities \u25cfenhanced discovery, access and reuse of data collections (FAIR) \u25cfhigh scientific relevance for Earth system Science data producers and reusers Summary This poster gives an overview of the integration of five FAIRCORE4EOSC components into ENES RI and the long-term benefits for Earth System Science researchers and beyond. The use of FAIRCORE4EOSC components RAiDs, DTR, MSCR, PIDGraph and RDGraph improve discoverability, reusability and traceability of ENES data. Adaption of FAIRCORE4EOSC components for FAIR data management for Earth System Science within the case study \u2018Climate Change\u2019 ENES-RI ENES-RI is the research infrastructure for European Network for Earth System modelling (ENES), a collaboration of partners in climate modelling, climate impact research, IT and data management. The ENES-RI aims to \u25cfdeliver services to access climate model data \u25cfdevelop tools to boost the understanding of future climate variability and change \u25cfprovide climate projections for policy decisions on mitigation and adaptation strategies, e.g. by the Intergovernmental Panel on Climate Change (IPCC) Anna-Lena Fl\u00fcgel fluegel@dkrz.de Acknowledgement This work has been funded by the European Commission under the projects IS-ENES grant no. 824084 (H2020) and FAIRCORE4EOSC grant no. 101057264 (HE) References FC4E https://faircore4eosc.eu ENES https://is.enes.org EOSC https://eosc.eu", "label": "poster"}
{"text": "Display of Results Running Taverna Workflows within IPython Notebook Alan Williams, Aleksandra Pawlik, Carole Goble, University of Manchester, UK Future Work Collation of provenance \u2022 The provenance of the workflow runs will be linked with the history generated by IPython Notebook Creation of Research Objects \u2022 Combine the IPython Notebook, the workflows and the linked provenance within a \u201cResearch Object\u201d - http://www.researchobject.org/ Creation of documentation \u2022 Use IPython or dexy to generate reports about workflow runs Running the Taverna Player directly on the Taverna Server \u2022 The Taverna Player currently has to be within a Taverna Portal, or similar workflow registry. \u2022 In the future, Taverna Player will be extended to run directly against a Taverna Server \u2022 Will allow running of \u201carbitrary\u201d workflows and allow them to be exposed in IPython Notebook Improved interaction \u2022 Allow the data entered in an interaction to come from values within IPython Notebook Teaching \u2022 Use the combination of IPython Notebook and Taverna to provide training materials Taverna Player \u2022 Allows Taverna workflows to be run as part of a website like embedding a video from Youtube \u2022 Uses Taverna Portal for user authorization \u2022 Reads workflows from a Taverna Portal \u2022 Runs workflows on a Taverna Server \u2022 Has a REST API Links IPython and IPython Notebook www.ipython.org The Taverna Player code on GitHub at www.github.com/myGrid/taverna-player The Taverna Player Client package at www.pypi.python.org/pypi/tavernaPlayerClient and the code on GitHub at www.github.com/myGrid/DataHackLeiden Taverna\u2019s homepage at www.taverna.org.uk Acknowledgments This work was enabled by the BioVeL project, that has received funding from the European Union\u2019s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 283359, and also enabled by the Software Sustainability Institute supported by the UK Engineering and Physical Sciences Research Council (EPSRC) through grant EP/H043160/1 Much of the work on the Taverna Player Client was carried out during the \u201cData enrichment hackathon\u201d organized by pro-IBiosphere. Thanks are due to Ross Mounce of the University of Bath, UK and to Youri Lammers of Naturalis, Netherlands for their work on the client during the hackathon. Thanks are also due to the developers of IPython Notebook for their help and advise during the hackathon. Architecture Use Case The example notebook shows the running of a series of workflows for Ecological Niche Modelling (ENM), using the Taverna Player Client and the pandas and random Python packages. A file of csv data representing occurrences of species is read. 100 rows are selected at random for use in the Ecological Niche Modelling. A model is created and projected for the present day and for 2050. The results of the ENM are re-organized and then used as inputs to two other workflows: one to produce statistics and one to calculate the differences (climatic effects) between the projections. Client Creation Taverna Player Client \u2022 Uses Taverna Player and its Server to run workflows within an IPython Notebook \u2022 Data passed from the Notebook to the executing Taverna Workflows \u2022 Workflow run\u2019s requests for data answered within the Notebook using Taverna\u2019s interaction service \u2022 Results retrieved from the run and fed back into the Notebook \u2022 Available from the PyPi registry \u2022 Tested with BioVeL workflows for data refinement and ecological niche modelling. Interaction with Run Organization of Data Taverna Server \u2022 Runs arbitrary Taverna 2 workflows \u2022 Secure, isolated, user-specific workflow execution \u2022 Manages data for separate runs \u2022 Publishes interactions and provenance Use Case Introduction IPython Notebook, originally developed by Fernando Perez of University of Berkeley (where the core development team is currently based) is a browser-based environment for interactive computing. Users can write, edit and re-run Python scripts. IPython Notebook has suppor", "label": "poster"}
{"text": "An MPC Framework for Online Motion Planning in Human-Robot Collaborative Tasks Motion planners in human-robot collaboration must: \uf0a7 Be fast (online with sampling period of few ms) \uf0a7 Be optimal \uf0a7 Reactto the human state (and prediction) We propose a recedinghorizonframework thatruns online in less than1 ms and adapts the robot motion to the state of the operator. Main features: \uf0a7Stackof tasks(SoT) : \uf0a7Online trajectoryscalingto slow down the task whenthe operator isclose to the robot without modifying the path \uf0a7Redundancyisusedto keep the robot far from the human \uf0a7Robot constraintsare explicitly taken into account Marco Faroni Manuel Beschi Nicola Pedrocchi CNR-STIIMA marco.faroni@stiima.cnr.it Thanks to the trajectory scaling, the geometrical curve is preserved: \uf0a7when the human is closer than the safetythreshold, the trajectory is slowed down \uf0a7when the distance is below the stoppingthreshold, the trajectory reaches null velocities The plannerusesthe redundancy to keepthe robot farther from the operator whenthe human is in the robot workspace(blackline always above blue line) stopping threshold scaling activation threshold clearance activation threshold Experimental test case: \uf0a7Universal robot UR5 on a linear guide (7 degrees of freedom) \uf0a7Pick-and-place ripetitive cartesian task \uf0a7Limits on joint positions, velocities, and accelerations \uf0a7Human position is provided by 4 time-of-fly cameras The research leading to these results was partially funded by the European Union H2020-ICT-2017-1 \u2013 Pickplace: Flexible, safe and dependable robotic part handling in industrial environment (grant agreement: 780488). 1. CARTESIAN TASK 2. VELOCITY SCALING 3. CLEARANCE", "label": "poster"}
{"text": "Henning Lange-Asschenfeldt Response of assumed interfacial charge carrier turbulence in interconnected electrical conductors to thermal diffusion or gravitational force Section from circuit or particulate structure 1 2 Two-component design (e.g. Fe/Ni or Si/C, roughly schematic) 1 2 - A comparative view - Interfacial transition zone (ITZ) Original (unaffected) state (Dynamic polarisation site) Available heat consumption Minor support current Translocation of charge carrier turbulence Gravitational force particulate solid structure Summation effect in ? (regulated) (Attraction) Gravitoelectric effect 2 Proportionate intensification Heat supply Thermoelectric effect (Seebeck) 1 of charge carrier turbulence Poster contribution", "label": "poster"}
{"text": "Resistance breaking strains of tomato spotted wilt orthotospovirus: distribution and evaluation of their impact on tomato and pepper production Funding Non-competitive funding mechanism. Each funder only pays for the participation of their own national researchers. Total funding \u20ac 50 000 Picture 1 Picture 1 Picture 1 Goals The goal of the project is to investigate the tomato spotted wilt orthotospovirus\u2019 genome differences between resistance breaking (RB) isolates from tomato and pepper and non-RB isolates of these hosts. This investigation seeks to clarify if previous reports of genome motifs responsible for RB phenotypes are universally present in RB isolates from geographically distant areas Research consortium DAF (AU), CREA (IT), NIB (SI) Contact information Project coordinator: Cherie Gambley Cherie.Gambley@daf.qld.gov.au Key outputs and results The expected project results are: \u2022 knowledge of the impact of resistance breaking isolates in Australia, Italy and Slovenia \u2022 a collection of geographically diverse, phenotypically and molecularly characterised, isolates of tomato spotted wilt orthotospovirus \u2022 knowledge of the virus genetics: clarification of the presence of the putative single amino acid changes at positions Y118 or N120 in the non- structural protein (NSm) gene in RB-tomato isolates or identification of alternative putative motifs responsible for the RB phenotype in tomato, pepper and weed hosts Objectives The project objectives are: \u2022 to collect and phenotype a range of tomato spotted wilt orthotospovirus isolates from pepper, tomato and other hosts including weed species from Australia, Italy and Slovenia \u2022 to generate full genome sequences of these isolates \u2022 to compare full genome sequences of RB isolates and non-RB isolates to identify differences that potentially confer the RB phenotype \u2022 to review diagnostic protocols for the detection of RB isolates on the basis of the newly derived genomic data 03/2021-02/2023", "label": "poster"}
{"text": "Metadata: Conditions data Handling Detector Characterization Data (Metadata) in XENONnT Conditions Data Processed Data Metadata Storage As an example, in XENONnT we needed to track crucial detector conditions like liquid xenon purity, which we monitor in terms of the electron lifetime. The electron lifetime determines the likelihood of electron absorption by impurities, thereby affecting energy reconstruction of interactions. How we calculate this value has changed over time so we needed to keep track of these multiple methods via different versions. Red: 222Rn alpha, Blue: 83mKr, green: 37Ar. Including the condition by charge up Electric \ufb01eld model. Gray band is the measurement by purity monitor, with systematic uncertainty. RFrame is a metadata framework that offers indexing features, similar to Pandas dataframes, but can operate on multiple storage backends. The goal of RFrame is to provide the following properties: \u25cf Support for multi-indexing using discrete or continuous values, allowing for complex data structures to be easily represented. \u25cf Checking and enforcement of values and index data types to ensure data integrity and consistency. \u25cf Arbitrary rules for reading and writing to the database, giving developers \ufb02exibility in how they interact with the data. \u25cf Support multiple data access storages. \u25cf Python functions can be used to insert, delete, and modify data, allowing for easy integration with existing codebases. Xedocs was built based on RFrame and it handles the XENONnT speci\ufb01c needs for metadata management. At its core, xedocs consists of a collection of schemas that de\ufb01ne the rules that different kinds of metadata need to follow. Base corrections Time sampled Time interval Base resource reference Map corrections Example: Electron Lifetime By: Luis Sanchez, Rice University, USA Yossi Mosbacher, Weizmann institute of science, Israel Aaron Higuera, Rice University, USA Christopher Tunnell, Rice University, USA RFrame Xedocs JSON Mongo Tinydb Our processing pipeline uses global versions, which is a list of lineages specifying the version of all the conditions metadata used to process a set of data. The conditions metadata can be separated into 2 broad categories: \u25cf ONLINE version: Updated periodically and allows for extrapolation of values. Values here can only be changed in the future in terms of the time index. \u25cf OFFLINE version: Allows for interpolation when processing a data segment with values before and after the time the data was taken. Of\ufb02ine versions can become obsolete as they are replaced with new versions. Raw Data Processing Pipeline Experiment Links To code: \u25cfhttps://github.com/jmosbacher/rframe \u25cfhttps://github.com/XENONnT/xedocs Experiment Monitoring Tools Manual Inputs - Version indexing - Time indexing - Updating rules - Other conditions metadata dependent requirements xarray API ODM API Has its own versioning system Pandas df Lists Dicts - _Alias attribute is always unique - Schemas include a versioned index - Changing already set values is not allowed - Adds an interpolation index of type datetime - Enforces rules on inserting new data points - Adds an interval index of type datetime. - Enforces rules on updating intervals. - Requires existence of resource in a database prior to inserting a new document - Requires an \u2018algorithm\u2019 index of type string. These schemas can be used to de\ufb01ne the different kinds of conditions metadata we need and are built inheriting for the previous one. API\u2019s Data backends In memory datatypes Many experiments have their own system to store, organize and track conditions data, but in many cases it is not possible to copy the system of another experiment due to how specialized to their experiment this system will be. In XENONnT we developed an open source tool in python to facilitate conditions data management and storage, which we call rframe and xedocs. We needed tools to handle versioned and time-indexed conditions data, as well as to impose rules regarding how the va", "label": "poster"}
{"text": "Rapid \u201cmix-n-match\u201d evolution of a housekeeping protein in response to bacterial antagonism EmilyClare Baker \u00b9, Kristin Kohler\u00b9, Matt Barber\u00b9 \u00b9University of Oregon Institute of Ecology and Evolution Based on PAML\u2075 analysis of CEACAM proteins from 19 hominid, Old World Monkey and New World Monkey primates. The CEACAM protein family\u2074 A multifunctional cell adhesion family in vertebrates N domain (IgV-like) IgC2-like domains* TM Cytoplasmic domain protein-protein binding domain includes ITIMs and other signaling motifs* (*presence and composition variable) *Number varies from 0 to 6 between different proteins and isoforms CEACAM protein domain structure Several bound by bacteria \u2022 CEACAM1 \u2022 CEACAM5 (CEA) \u2022 CEACAM6 \u2022 CEACAM3 Functions include... \u2022 Cell adhesion \u2022 Intra- and Intercellular signaling \u2022 Immune function \u2022 Cell cycle modulation CEACAMs 1, 5 & 6 \u2022 strong markers of cancer progression and prognosis \u2022 expressed on epithelia (esp. gastric) and immune cells \u2022 housekeeping proteins involved in cellular signaling CEACAM3 \u2022 expressed on immune cells \u2022 likely a dedicated immune protein Region bound by bacterial adhesins CEACAMs bound by bacterial adhesins the most rapidly evolving in primates \u2022 niche construction \u2022 immune evasion Bacterial adhesin proteins can exploit cell surface proteins for...\u2074 \u2022 movement through the host Potentially decreasing host fitness bacterial adhesin \u2013 host protein interactions Consequences of evolutionary conflict between pathogens and host \u2018housekeeping genes\u2019 \u2022 Pathogen antagonism is predicted to lead to an \u2018evolutionary arms race\u2019 \u2013 characterized by rapid evolution host and bacterial proteins. Model of bacterial adhesin host protein evolutionary arms race 1 Bacterial adhesin is unable to bind to the host epithelial protein 2 Pressure to manipulate host drives evolution of bacterial adhesin to bind host protein 3 Pressure to prevent exploitation favors evolution of host protein away from adhesin binding 4 Pressure to evolve shifts back to the bacterial adhesin If and how housekeeping genes can evolve against pathogen exploitation is unclear. How host \u2018housekeeping\u2019 proteins can evolve to evade pathogen exploitation and maintain essential functions is an open question. Sites under selection are concentrated in the N-domains* domain targeted by bacterial adhesins * based on NS-sites analysis in PAML HopQ CEACAM1 N-domain Some sites under selection localize to interface with H. pylori HopQ Highlighted sites indicated as under selection by phylogenetic analysis programs PAML, FEL\u2076 and MEME\u2077 Bonobo CEACAM1 N-domain is unable to bind HopQ and has unusually divergend protein sequence 1. Correa P, Piazuelo MB. Evolutionary history of the Helicobacter pylori genome: Implications for gastric carcinogenesis. Gut Liver. 2012;6: 21\u201328. doi:10.5009/gnl.2012.6.1.21 2. Ishaq S, Nunn L. Helicobacter pylori and gastric cancer: A state of the art review. Gastroenterol Hepatol from Bed to Bench. 2015;8: S6\u2013S14. 3. Javaheri A, Kruse T, Moonens K, Mej\u00edas-luque R, Debraekeleer A, Asche CI, et al. Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs. Nat Microbiol. 2016;17: 16189. doi:10.1038/nmicrobiol.2016.189 4. Gray-Owen SD, Blumberg RS. CEACAM1: Contact-dependent control of immunity. Nat Rev Immunol. 2006;6: 433\u2013446. doi:10.1038/nri1864 5. Yang Z. 2007. PAML 4: phylogenetic analysis by maximum likelihood. Mol Biol Evol. 24:1586\u20131591. 6. Kosakovsky Pond SL, Frost SD. Not so different after all: a comparison of methods for detecting amino acid sites under selection. Molecular biology and evolution. 2005 May 1;22(5):1208-22. 7. Murrell B, Wertheim JO, Moola S, Weighill T, Scheffler K, Pond SL. Detecting individual sites subject to episodic diversifying selection. PLoS genetics. 2012 Jul;8(7). 8. Guindon S, Dufayard JF, Lefort V, Anisimova M, Hordijk W, Gascuel O. New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst", "label": "poster"}
{"text": "Demobase: DEsign and MOdelling for improved BAttery Safety and Efficiency Headline Converging the efforts of the GV7 call, which is addressing efficiency and cost reduction on the integration related aspects of motors, power electronics and transmission, DEMOBASE aims at the generation of the necessary tools and technology solutions that will drastically reduce price differences between conventional and electric vehicles while assuring much lower operational cost, higher efficiency, higher availability, increased driving range as well as improved comfort and attractiveness. In DEMOBASE, cost reduction activities, higher car performances and availability, mainly on the key battery system component, will be achieved through incremental and breakthrough research activities and demonstrated in a dedicated demonstration vehicle. The EV demonstration focuses on the sector of electro-mobility with the highest growth, i.e. four wheels urban vehicles. These activities will be supported by highly advanced multi- level and multi-domain simulation. A key aspect will be gateway development to ensure the seamless process effectiveness for a variety of software environments. Specific objectives: \u2022 Cost reduction of batteries: will be tackled by a seamless development chain with drastically reduced development time and costs, enabling as an additional benefit also faster integration of new cells. An innovative seamless development process from cell and from active material to vehicle using multi-level modelling integrating battery management, ageing, safety, recycling and availability will cut down development time by at least factor 2. \u2022 Cost reduction of chassis: The methodology developed with the FP7 PLUS MOBY project ended December 2016 will be further advanced in DEMOBASE making it (ubiquitous) parametric and applicable to most vehicle categories. DEMOBASE will develop and demonstrate breakthrough methodology that allows the design and development of novel safe chassis in less than one tenths the usual time and at a small fraction of the usual cost. \u2022 Battery safety: improved without additional expense, battery risks will be addressed by a fail aware concept to ease vehicle fleet management. DEMOBASE develops new safety approach based on tests at cell level and innovative battery model to manage fire risk, gas flammability, gas toxicity at vehicle level. \u2022 Battery availability: The new battery system functionalities make it immune to thermal runaway events. Residual fire or thermal runaway risk will be managed inside the vehicle without stop of service, which is the today\u2019s standard fail safe management, with fail operational concept supported by specific battery architecture and innovative safety components. \u2022 Accelerated battery ageing modelling: Innovative characterization technics are used to develop battery ageing models within 4 months. \u2022 Battery recycling as part of the process: To close the life cycle, tools and recommendations for safe and efficient recycling will be elaborated. DEMOBASE develops End to End safety activities from active material to recycling where recycling is part of the overall development process. Moreover the novel approach for chassis design leads to radical reduction of the large quantity of adhesives currently used in the automotive world, easies disassembling of the elements composing the full vehicle; it is another mind shift in auto world. This will reduce the recycling costs by up to 25%. \u2022 Radical reduction of the necessary investments: Process capability for a variety of different vehicle architectures derived from a single chassis will be demonstrated. \u2022 Scalability of design for both vehicle and battery system: a parametric methodology to design and developed batteries and a new chassis will be demonstrated for different vehicle classes. \u2022 The efficiency of e-drivetrains under real conditions will be increased by 20%. For this purpose, the project will develop and demonstrate wheel-tire design wit", "label": "poster"}
{"text": "t Funded by the Horizon 2020 Framework Programme of the European Union THIS PROJECT HAS RECEIVED FUNDING FROM THE EUROPEAN UNION\u2019S HORIZON 2020 RESEARCH AND INNOVATION PROGRAMME UNDER GRANT AGREEMENT NO. 818309 (LEX4BIO). THIS OUTPUT REFLECTS ONLY THE AUTHOR\u2019S VIEW AND THE EUROPEAN UNION CANNOT BE HELD RESPONSIBLE FOR ANY USE THAT MAY BE MADE OF THE INFORMATION CONTAINED THEREIN. Plant nutrient and harmfull heavy metal concentrations in agricultural soils of EU27 and UK Kari Ylivainio1, H. Eigner3, S. Geyer3, A. Skytt\u00e41, L. Jauhiainen1, A. Delgado4, A. Jones5, J. Santner2 1Natural Resources Institute Finland (Luke), Jokioinen, Finland, 2Department of Crop Sciences, Institute of Agronomy, University of Natural Resources and Life Sciences, Vienna, Austria, 3Agrana Research & Innovation Center GmbH, Tulln, Austria, 4University of Sevilla, Spain, 5Joint Research Center (JRC), Ispra, Italy Introduction Farm-to-Fork strategy aims to reduce nutrient losses by 50%, which is expected to decrease the requirement for fertilisers by 20% by the year 2030. To reach these ambitious targets, it is of utmost importance to know the nutrient status of agricultural soils for optimising fertilisation according to crop requirement. Furthermore, substitution of mineral fertilisers with bio-based fertilisers (BBF) reduces the need for finite phosphorus (P) resources and production of energy intensive mineral nitrogen (N) fertilisers. However, BBFs may contain other elements than only desired plant nutrients. Therefore, both nutrient and harmful heavy metal concentrations in BBFs and agricultural soils needs to be known in order to select technologies for producing safe BBFs for ensuring food and feed safety. Material and methods In this study, a sub-set of soil samples from the LUCAS soil sample archive, collected in 2015 (https://publications.jrc.ec.europa.eu/repository/handle/JRC 107926), were analysed for their soluble elemental composition. The selection of soil samples from the EU27+UK was based on proportional allocation with the following criteria: soil pH, carbonate content, texture, organic carbon content, and Olsen-P values. A total of 1,661 soil samples from cropland (out of 9,246 samples) were selected and soluble concentrations of P, K, Zn, Cu, Pb and Ni were analysed with the electro-ultrafiltration (EUF) method . Results \uf0d8Soluble P concentration varies greatly across Europe with highest concentrations in western Europe (Fig. 1) \uf0d8Soil K concentrations are evenly distributed in Europe \uf0d8Highest concentration of Zn follows the same pattern as P \uf0d8High Cu concentrations were found from the Mediterranean region. \uf0d8Highest average Pb concentrations were found from the western Europe, whereas Ni concentration were more elevated in the eastern Europe. Conclusions \uf0d8 Requirement for P fertilization varies across Europe and high soil P and Zn concentrations are found in regions with high animal density \uf0d8 Concentration of soil Cu high in regions with vineyards and orchards, probably originating from pesticides \uf0d8 Soluble Pb concentration follows the same trend with Zn, whereas high Ni concentrations may be due to indigenous soil properties \uf0d8 Due to the variation in soluble elemental composition of agricultural soils in Europe, properties of BBFs needs to match to local soil conditions in order to secure food and feed safety and minimize environmental losses Figure 1. Soluble P, K, Zn, Cu, Pb and Ni concentrations in European croplands (EU27 + UK) according to the EUF-method", "label": "poster"}
{"text": "Filter Testing Services for Pharmaceutical and Medical Device Manufacturers STEMart, a US-based provider of comprehensive services for all phases of medical device development, has announced the launch of its new Filter Testing Services for pharmaceutical and medical device manufacturers. These services are designed to help manufacturers ensure the safety and efficacy of their products by verifying the performance of filters used in the manufacturing process. Filtration sterilization is an important unit operation in the aseptic manufacturing process. It requires proper process validation to verify the performance of the filters used for sterilization filtration. Filter testing is used to evaluate a filter's ability to separate microorganisms of various sizes and helps manufacturers determine membrane pore size. This test is also an excellent batch release test. Test data can also be used as an effective marketing tool. STEMart provides comprehensive facility and process validation for medical devices. With extensive expertise in Filter Testing, STEMart can provide a full service experience to assist manufacturers in meeting regulatory goals and minimizing compliance risks. The comprehensive Filter Testing services are guided by \"Sterile Drug Products Produced by Aseptic Processing - Current Good Manufacturing Practice\", the FDA guidance document for industry, which outlines the general considerations the FDA believes should be taken into account when performing filter testing for a medical device. STEMart offers a wide range of Filter Testing services. For example, Retention Capacity and Filtration Efficiency Test demonstrates the filter's ability to remove all bacteria from a liquid bacterial suspension under specified conditions according to ASTM 838-05. Validation of the filtration process takes into account all factors that may affect the performance of the filter, such as pH, viscosity and compatibility of the material being filtered with the filter, flow rate, pressure, temperature, and hydraulic shock. Filter Extractables Test identifies and quantifies compounds that have the potential to become leachables. Suitability Test verifies that the filter meets all requirements under product and process conditions, including, but not limited to, resistance to high temperatures, resistance to fatigue under pressure and flow changes, and resistance to high pressure changes. Based on ISO 10992 and ISO 18562 standards, FDA guidelines, ASTM (American Society for Testing and Materials) standards and other international guidelines, STEMart's experts have many years of experience in a wide range of testing services for Class I, II and III medical devices and can help clients ensure that every aspect of the medical device is properly tested. If you have additional questions about Filter Testing or would like to find out more", "label": "poster"}
{"text": "Estimating Mutation Parameters and Population History Simultaneously from Temporally-Spaced Genome Data Arman Bilge, Tanja Stadler, Matthew Kearse, and Alexei J. Drummond email: abil933@aucklanduni.ac.nz Estimating Mutation Parameters and Population History Simultaneously from Temporally-Spaced Genome Data Arman Bilge, Tanja Stadler, Matthew Kearse, and Alexei J. Drummond email: abil933@aucklanduni.ac.nz Motivation and Primary Challenges \u25b7Very feasible to sequence entire genomes \u25b7More recently, even possible to recover ancient genomes \u25b7Temporally-spaced genome data \u25b7Opportunity to do inference previously only possible for fast-evolving organisms (e.g., viruses) \u25b7mutation rate \u25b7population size through time But. . . \u25b7Di\ufb03cult to phase diploid genomes \u25b7Recombination \u25b7Low coverage and sequencing error, especially for ancient genomes \u25b7Cannot use existing Bayesian phylogenetic methods Sequencing Depth and Error \u25b7Assume that all individuals have about same number of SNPs \u25b7Average sequencing depth of sample is correlated with observed SNPs \u25b7Our dataset approaches complete SNP recovery at 22x coverage \u25b7Ancient genomes are sequenced at lower depth and thus missing many SNPs \u25b7Leads to systematic bias in estimates 4 8 12 16 20 24 28 4 4.5 5 5.5 6 6.5 7 \u00b7106 Average Depth Recovered SNPs Overview of Methodology \u25b7Want to estimate mutation and population parameters \u03b8 from pileup data \u25b7pileup data is unsummarized, aligned reads for each sampled individual \u25b7To compute posterior need to marginalize over individual\u2019s genotypes \u25b7Computationally intractable so use importance sampling \u25b7The importance distribution assumes independence of individual\u2019s genotypes P (\u03b8 | D) = X G P (\u03b8 | G) P (G | D) = lim n\u2192\u221e n X i=1 P \u0010 \u03b8 | G (i)\u0011 P \u0000G (i) | D \u0001 \u02c6P \u0000G (i) | D \u0001, G (i) \u223c\u02c6P (\u00b7 | D) \u25b7Finally, use standard MCMC to sample parameters for a given genotype P (\u03b8 | G) \u221dP (G | \u03b8) P (\u03b8) Sampling an Individual\u2019s Genotype \u25b7Want the genotype g1, g2 \u2208{A, C, G, T} of individual at a position in its genome \u25b7Data is the observed base calls at this position with their Phred quality scores D = (bq : b \u2208{A, C, G, T} , q \u2208N) \u25b7Number of base calls |D| is the sequencing depth at this position \u25b7Sample genotype from the posterior distribution P (g1, g2 | D) = P (D | g1, g2) P (g1) P (g2) P (D) \u25b7To compute P (D | g1, g2) assume base calls are multinomially distributed with probabilities P (bq | g1, g2) = 1 2P (bq | g1) + 1 2P (bq | g2) \u25b7Using the de\ufb01nition of a Phred quality score (assuming equal error rates for all bases) P (gi | bq) = ( 1 \u221210 \u2212q 10 ifb = gi 1 310 \u2212q 10 ifb \u0338= gi we have P (bq | gi) = P (gi | bq) P (bq) P (gi) \u25b7Use empirical estimates for P (gi) and P (bq) Genotype Probability \u25b7Assumes that sites are unlinked; i.e., phylogenetically independent \u25b7Models recombination with no dependence on correct phasing \u25b7Assumes a site is biallelic; i.e., has only two possible nucleotide states \u25b7Often true in practice \u25b7Can be handled rigorously with ascertainment bias correction \u25b7Want the probability of all the individuals\u2019 genotypes by marginalizing over all phylogenies P (G | \u03b8) = Z T P (G | T, \u03b8) P (T | \u03b8) dT \u25b7Integral is computed numerically using similar technique to SNAPP [2] \u25b7Divide time into intervals using sampling times and population change times \u25b7Each interval i can be described by a linear system of di\ufb00erential equations Qi \u25b7Solve each system by taking the matrix exponential exp Qi [1] \u25b7Can be done e\ufb03ciently by caching and reusing matrix exponentials Simulation Study \u25b78 diploid taxa, including 4 ancient individuals up to 50k years old \u25b7Mutation rate \u00b5 = 10\u22129 s/s/yr \u25b7HKY model with \u03ba = 5 \u25b7Constant size population with Ne = 3 \u00d7 106 \u25b7Simulated 50 datasets of 104 total sites \u25b7Attempted to infer parameters \u25b7True values always within 95% HPD \u25b7Mean \u02c6\u00b5 within \u00b11.8 \u00d7 10\u221210 of true \u00b5 G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 0e+00 1e\u221209 2e\u221209 3e\u221209 0 10 20 30 40 50 replicates Mean Summary \u25b7Fully Bayesian inference of mut", "label": "poster"}
{"text": "An assessment of potential Plato Observing strategies to maximize science return from the Kepler Field. J.F. Rowe, D. Jontof-Hutter, J. Lissauer Bishop\u2019s University, University of the Pacific, NASA-Ames The Plato Mission has the unique capacity to provide long-base observations of thousands of stars and their transiting planets. The current mission plan includes a 2-year stare than includes the Kepler Field. Plato observations have the potential to improve science return from the Kepler field. Including, the reliability of Kepler planet candidates in the low S/N regime, detection of long-period planets and an overall improvement of exoplanet occurrence rates and transit timing variations and long-term stellar variability and stellar cycles. The low S/N transit regime includes potential Earth-sized habitable zone planets around Sun-like stars, which is of high intellectual interest. Abstract Kepler Planets Plato detection SNR in the Kepler Field The baseline Plato mission includes a 24 month continuous stare that includes the Kepler Field. Due to orbital constraints, the Kepler is located towards the periphery of the Plato FOV and will be covered by 6 - 12 cameras. This is roughly equivalent to 1/8 to 1/4 of the Kepler light gathering ability. Figure 2, shows an estimate of the expected SNR of a planet transit in the Kepler Field observed by Plato. Of note, is the very low SNR recovery of long-period planets with a radius less that ~ 4 R\u2295. Figure 3 shows the hypothetical scenario of observing the Kepler Field, but centred in the Plato FOV. Note, this configuration is not possible. However, by centring the FOV, there is an overall increase in transit SNR recovery which greatly benefits planets smaller than 4 R\u2295. Figure 4 shows our proposed observing plan which would centre the Kepler Field, and to break the observing campaign into four 6-month campaigns. This gives the benefit of more Plato Glass on the Kepler field, but extends the observing baseline to 4- years, which allows for recovery of approximately half of Kepler\u2019s long-period Earth-sized planets. Notice the significant increase in SNR for planets with periods greater than 300 days and radii less than 4 R\u2295. Figure 1 shows the average SNR per transit vs orbital period and radius. The average SNR generally increases with radius. Trends associated with period are a result of the Kepler mission requiring a total SNR \u2273 7.1 for candidate selection, thus few transits requires a large average SNR per transit for detection threshold. Figure 1 Figure 3 Figure 4 Also: see Talk by J. Lissauer and Poster by D. Jontof-Hutter Figure 2", "label": "poster"}
{"text": "Meta The case: Nanocatalytic powders as coating in automotive industry Cu/Pd/Rh doped on Ce/Zr mixed oxide Nanosized copper-based catalyst for automotive: physicochemical characterization. A. Soto Beobide1, A. M. Moschovi2, G. N. Mathioudakis1, M. Kourtelesis2, Z. G Lada1, K. S. Andrikopoulos1,3, L. Syggelou1, V. Dracopoulos1, I. Yakoumis2, G.A. Voyiatzis1 1 Foundation for Research and Technology / Institute of Chemical Engineering Sciences FORTH/ICE-HT, Patras, Greece 2Monolithos Catalysts & Recycling Limited, Athens, Greece 3Department of Physics, University of Patras, Patras, Greece * E-mail address of presenting author: asoto@iceht.forth.gr I) Outline In the automotive industry, catalytic devices accumulate concentrated loading of platinum group metals (PGMs, platinum, palladium, rhodium) as the active catalytic phase. The aim of MONOLITHOS Catalysts Ltd is the partial substitution of an amount of PGMs (mainly platinum) with abundant non-PGMs (transition metals). Several efforts have been made to use transition metals as substitutes and among them copper seems to be one of the best. PROM100 \u201cfresh\u201d: catalyst that has not been used at all PROM100 \u201caged\u201d: artificially aging by submitting to hydrothermal (10% water) heating at 1050 oC for 4h. EU Directives for simulating more than 60,000Km of mileage of a car. Rama II) www.iceht.forth.gr Nanotechnology is conceived as a Key Enabling Technology, becoming an increasingly research area providing functional materials to many industrial sectors, such as automotive, health, packaging, textiles, construction, etc. The main objective of DIAGONAL project is to increase the understanding on Multi-Component NanoMaterials (MCNM) and High Aspect Ratio Nanoparticles (HARNS) behavior along their life cycle from NM design and production to its application into Nano-Enabled products (NEP). DIAGONAL aims to bring new methodologies to guarantee long-term nanosafety and contribute to fill current gaps in: Risk Assessment, Risk Management and Risk Governance. DIAGONAL will bring Safe-by-Design knowledge and tools to a development stage which can be implemented in the MCNM and HARNs related industries, relying on experimental (in vitro) and modelling (in silico) research to understand and ultimately predict the interactions among the NM components, their transformation products, and between the NMs and the environment, promoting a better understanding of potential adverse effects on human health, and biota. Metallic oxide NPs (Cu, Pd, Rh) over ceramic substrates of CeO2/ZrO2 (automotive catalytic converters for the transformation of toxic gases Physico-chemical characterization of PROM100 catalyst and its transformation along life cycle C) Raman Characterization E) X-ray diffraction, XRD Definition of Nanomaterial According to Commission\u2019s recommendation [1] Prometheus catalyst (PROM100) Material with 50% or more of the particles in the number size distribution, present one or more external dimensions in the size range 1 nm-100 nm A material should be also considered nano when the specific surface area by volume of the material is >60 m2/cm3 D) X-ray photoelectron spectroscopy, XPS A) Gas porosimetry Surface area Specific surface area by volume PROM100 fresh: 81m2/g 528 m2/cm3 (*) PROM100 aged: 1 m2/g 6.5 m2/cm3 *Density (CeZrO4)= 6.52 g/cm3 B) Scanning electron microscopy, SEM PROM100 fresh PROM100 aged 200 300 400 500 600 700 800 Relative Intensity Raman Shift, cm -1 470 615 \uf06c0=514 nm 200 300 400 500 600 700 800 Relative Intensity Raman Shift, cm-1 472.5 PROM100 fresh \uf076CeO2cubic fluorite: intensity peak at 465 cm-1 \uf076Ce1-xZrxO2mixed oxides: increasing x value -> shift to 470 cm-1 \uf076Broad and weak peak at ~620 cm-1: presence of oxygen vacancy in the fluorite phase which causes defects sites in Ce-Zr oxides for the activity of the catalyst [2] 200 300 400 500 600 700 800 638 616 567 537 383 348 333 306 258 221 190 Raman Shift, cm-1 178 \uf076Increase intensity peak Ce1-xZrxO2 at 472 cm-1 \uf076New peaks: ZrO2", "label": "poster"}
{"text": "Open-Access-B\u00fcro Berlin Der Berliner Senat hat im Rahmen der Open- Access-Strategie ein Koordinationsb\u00fcro eingerichtet. Das Open-Access-B\u00fcro Berlin ist am Center f\u00fcr Digitale Systeme der Freien Universit\u00e4t Berlin an- gesiedelt und hat am 1. September 2016 die Ar- beit aufgenommen. Das Open-Access-B\u00fcro Berlin hat die Aufgaben, die Berliner Wissenschafts- und Kultureinrich- tungen \u00fcber die Kernziele der Berliner Open- Access-Strategie aufzukl\u00e4ren, sie bei deren Um- setzung zu unterst\u00fctzen und die verschiedenen Akteure zu vernetzen. Kontakt Dr. Andreas H\u00fcbner E-Mail: andreas.huebner@open-access-berlin.de Dr. Katja Mruck E-Mail: katja.mruck@open-access-berlin.de Tel.: + 49 (0)30 838-50244 Adresse f\u00fcr Besucher/innen: Freie Universit\u00e4t Berlin Ehrenbergstra\u00dfe 26-28 14195 Berlin Postanschrift: c/o Freie Universit\u00e4t Berlin Center f\u00fcr Digitale Systeme (CeDiS) Ihnestr. 24 14195 Berlin www.open-access-berlin.de kontakt@open-access-berlin.de Andreas H\u00fcbner und Katja Mruck, Open-Access-B\u00fcro Berlin Das Land Berlin hat Ende 2015 eine Open-Access- Strategie verabschiedet, um den offenen Zugang und eine umfassende Nutzbarkeit im Sinne von Open Access in den Bereichen wissenschaftliche Publikationen, Forschungsdaten und Kulturelles Erbe zu f\u00f6rdern. Zielsetzungen Wissenschaftliche Publikationen Mit dem Jahr 2020 soll der Anteil an wissenschaft- lichen Open-Access-Publikationen (Gr\u00fcn und Gold) f\u00fcr Zeitschriften-Artikel aus allen wissenschaftli- chen Einrichtungen in der Zust\u00e4ndigkeit des Lan- des Berlin m\u00f6glichst bei 60% liegen. Monografien und Sammelb\u00e4nde sollten ebenfalls Open Access verf\u00fcgbar sein. Forschungsdaten Das Land Berlin setzt sich f\u00fcr den offenen Zu- gang zu und die Erm\u00f6glichung einer umfassenden Nachnutzung von Forschungsdaten ein und beab- sichtigt, konkrete Beitr\u00e4ge im Rahmen einer nati- onal und international abgestimmten Strategie zu leisten. Kulturelles Erbe Die bereits begonnene Digitalisierung des kultu- rellen Erbes des Landes Berlin wird fortgesetzt und erweitert. Das Land Berlin setzt sich f\u00fcr den offenen Zugang zu und die umfassende Nutzbar- keit von Kulturdaten ein. Der Aufbau von Kreativ- partnerschaften zwischen Akteuren aus Kultur, Kunst, Wissenschaft, Bildung, Forschung und Wirt- schaft wird unterst\u00fctzt. Open-Access-Strategie f\u00fcr Berlin Dieses Werk ist lizenziert unter einer Creative Commons Namensnennung 4.0 International Lizenz. Siehe http://creativecommons.org/licenses/by/4.0/ Text: Andreas H\u00fcbner und Katja Mruck, verwendetes Bildwerk: Matten Vogel", "label": "poster"}
{"text": "Sea slugs from the Gulf of Mexico", "label": "poster"}
{"text": "Direct imaging of magma oceans in nearby young stellar associations Irene Bonati a,b, Tim Lichtenberg *,b, Dan J. Bower c, Sascha P. Quanz d, Miles L. Timpe e a Earth-Life Science Institute, Tokyo Institute of Technology, Japan b Institute of Geophysics, ETH Z\u00fcrich, Switzerland c Center for Space and Habitability, University of Bern, Switzerland d Institute for Particle Physics and Astrophysics, ETH Z\u00fcrich, Switzerland e Institute for Computational Science, University of Z\u00fcrich, Switzerland * Presenter, now at: University of Oxford, United Kingdom irene.bonati@elsi.jp \u00d8 Terrestrial planets are thought to undergo multiple magma ocean (MO) stages as a result of heat released during accretion (giant impacts), decay of short- lived radioisotopes and core formation. \u00d8 Processes taking place during MO solidification set initial conditions for the planetary chemical structure, atmospheric composition, tectonic behavior, and habitability. \u00d8 Next-generation direct imaging techniques could lead to the detection of such bodies, thus providing observational constraints for theoretical models and insights into the origin and diversification of planets in our Solar System and beyond. \u00d8 We present a quantitative assessment of the observability of MO planets in nearby young stellar associations (SA) via future direct imaging facilities. II. 1D MO interior model2 I. N-body simulations1 \u00e0 Occurrence rate of giant impacts (GI) during planet formation around A, G and M- stars \u00e0 Surface temperature evolution after GIs \u00e0 MO cooling through atmosphe- res of different emissivities (0 \u2264\u03b5 \u22641) + steam atmosphere III. Telescope parameters: IWA + sensitivity \u2022 ELT ground telescope3 \u2022 Darwin-like space telescope4 \u00e0 Explore optimal target selec- tion strategy \u00e0 Constrain potential detectabi- lity of MO bodies IV. Probability of detecting at least one magma ocean planet in nearby stellar association5 References I. Timing and energy of giant impacts \u00d8 Q > Qcrit \u00e0 giant impact (GI) \u00d8 Most GIs occur within the first 20 Myr of planet formation. \u00d8 Post-impact bodies have radii 0.4 RE \u2264R \u22641.1 RE. \u00d8 Large planetary radius + low atmospheric emissivity \u00e0 long MO lifetime \u00d8 Evolution of steam atmosphere results in longer sustained MO \u00d8 MO planets at angular separations \u03b8 \u2265IWA \u00e0 detectable II. Magma ocean (MO) cooling timescales III a. Detectability assessment: Inner Working Angle (IWA) III b. Detectability assessment: sensitivity IV. Probability of detecting MO planets IWA = 2\u03bb D \u03b8 = tan\u22121 a d \" #$ % &' [1] Grimm & Stadel, ApJ, 796, 23 (2014) [2] Bower et al., Phys. Earth Planet. Inter., 274,49-62 (2018) [3] Brandl et al., SPIE (2016) [4] Kammerer & Quanz, A&A, 204 (2018) [5] Mamajek, Proc. IAU Symp. (2015) + ref. therein Methodology Results References Conclusions Motivation \u00d8 Target selection favoring young and close stellar associations containing a large amount of stars significantly increases the likelihood of detecting a MO event. \u00d8 \u03b2 Pictoris is the association best suited for potential future observations of collision-induced magma oceans, both with Darwin and ELT configurations. \u00d8 Planetary flux evolution during lifetime of a MO \u00d8 MO bodies having fluxes higher than telescope sensitivity thresholds \u00e0 detectable \u00d8 Observing mode: 30 h integration time for each star in a given stellar association \u03b8 = IWA Not detectable Detectable (inner working angle) 103 104 105 106 Time after GI (years) ! \" ! \" No. stars Association d (pc) Age (Myr) A G M \u03b2 Pictoris 15 23 4 18 21 AB Doradus 20.1 150 0 23 8 \u03b2 Tucanae 43 45 4 0 1 Tucana Horologium 48 45 2 27 5 Columba 50 42 2 37 1 TW Hydrae 53 10 2 0 33 Carina 65 45 0 22 0 32 Orionis 92 22 2 7 2 \u2318Chamaeleontis 94 11 1 0 11 \u03c71 For 99 50 2 0 0 PMO(\u03bbcen, d, \u2327\u21e4, \u270f) = 1 \u2212 i=n\u21e4 Y i=1 1 \u2212\u00afnGI,i \u00b7 \u2206tobs \u00afR,i \u2206tbin,i ! GI", "label": "poster"}
{"text": "The province of Alberta is home to one of the World\u2019s largest sedimentary basins. And the Oil and Gas industry has been Alberta\u2019s main source of economic prosperity for more than half a century. The oil sand deposits are the province\u2019s biggest oil producers, and due to the nature of bitumen and heavy oil, enhanced oil recovery techniques such as Steam- Assisted Gravity Drainage or SAGD are required. Oil and Gas and in particular the oil sands operations, have raised lots of negative Environmental concerns. And In addition, in recent years the government and companies have faced immense liabilities by the nonproducing wells. Alberta has one of the most polluting Grids across Canada and this is mainly because of Fossil Fuels. All these issues raise the demand for more alternative reliable sources of clean energy with little environmental impacts. Given the huge Sedimentary Basin and existing infrastructure geothermal energy has a good potential to be investigated and developed in Alberta. Geothermal Energy is the heat derived from the earth\u2019s subsurface, can be Harnessed for Clean Electricity generation or space heating applications. The main advantages of geothermal energy is being weather independent, and its very high capacity factor. By providing sustainable clean energy solutions using Geothermal potential, Renewable Energy can penetrate the Alberta Grid to lower the GHG emissions, and since infrastructure such as drilled wells already do exists, a big portion of money needed for the initial investment can be eliminated. This project provides solution for decommissioned wells which are hazardous risk to human health and the environment and huge financial liabilities for government and companies. Converting just 10 percent of Alberta\u2019s thousands suspended wells to geothermal can create business and work for hundreds of services and defer the high cost of well abandonment for companies Plus additional potential revenue from carbon tax credit by Reducing GHG emissions. Methods Conclusions Geologic Thermal Heat Storage and Recovery Alberta Sedimentary basin Sarvenaz Moazami - M.Sc. Student in Sustainable Energy Development, University of Calgary Introduction Results GeoThermal Heat storage \u2022 4000 Solar troughs \u2022 Area of 200,000 m2 \u2022 Steam injected to Geothermal Storage \u2022 3650 m3/day steam for storage \u2022 12 pairs would be sufficient, 1 Depleted PAD \u2022 More than 4100 tCo2 reduced \u2022 93% less than base case if Natural Gas used \u2022 $111k in Carbon Tax Credit \u2022 Initial investment $6.5 mil \u2022 NPV: $1.3 mil \u2022 LCOE 12 c/kWh References Wendt, e. a. (2019). Geologic Thermal Energy Storage of Solar Heat to Provide a Source of Dispatchable Renewable Power and Seasonal Energy Storage Capacity. GRC Transactions, 73-91. Ghoreishi-Madiseh, S., Templeton, J., Hassani, F., Al-Khawja, M., & Aflaki, E. (2014). Geothermal Energy Extraction From Decommissioned Petroleum Wells. Asian Rock Mechanism, 2644-2653. Bloomquist, D. R. (2012). Geothermal Space Heating. Washington State University Energy Program . Holman, J. P. (2009). Heat Transfer. In J. P. Holman, Heat Transfer (p. 752). McGraw-Hill Education. Urieli, I. (2020). Refrigerant and Heat Pumps. Retrieved from https://www.ohio.edu/mechanical/thermo/intro/chapt.1_6/chapter4c.html Reid, J. (2017). Geothermal Heat in Calgary: An Oil and Gas Retrofit. Calgary: University of Calgary. GeoThermal Heat storage 100% Renewable Microgrid, for 1000 Households in Firebag near Fort McMurray Solar Troughs for heat collection and Depleted SAGD pads for steam storage acting as synthetic Geothermal reservoir In Firebag, this means a Micro Grid of 1 MW Capacity, 7 GWh Electricity generation GeoThermal Space Heating For Geothermal Space heating facility design in Turner Valley, a model was designed for nearby residential buildings Temperature to stay around 25degC even during the coldest month of the year, for a 1000 households a Thermal Power Capacity of 5MW is needed. 18 GWh thermal energy Turner Valley field is produc", "label": "poster"}
{"text": "Application PHOTO\u2013SENS Project \uf0d8 EU-funded project of the program Horizon 2020 \uf0d8 New generic tool with integrated optical sensing circuits for ultra-sensitive detection \uf0d8 Wafer scale fabrication for cost-effective disposable bio-sensor \uf0d8 Microfluidics cartridge enabling sample treatment & transfer of various water\u2013based samples \uf0d8 Functional and easy-to-use read-out device for use with disposable bio-sensing cartridge \uf0d8 Identification of aquaculture-specific pathogens and respective biomarkers & serving as testing hub for fish farms Disposable cartridge: \uf0d8 Microfluidic system \uf0d8 Integrated buffers \uf0d8 Integrated sensor chip Device Design: \uf0d8 Cartridge handling \uf0d8 Sample application \uf0d8 Cartridge processing \uf0d8 Final Product (Future): \uf0d8 Industrial design \uf0d8 User guidance \uf0d8 Full automation \uf0d8 Six sensor channels \uf0d8 Two channels for process control Sensor chip: \uf0d8 Miniature optical system \uf0d8 Interference based on laser with modulated wavelength Assay development: \uf0d8 Pathogen detection \uf0d8 Early sturgeon sex detection \uf0d8 Based on double stranded DNA Device Concepts: \uf0d8 Liquid control \uf0d8 Temperature control \uf0d8 Sensor read-out Chip Development Device Development Optimization Surface coating: \uf0d8 Anti-fouling \uf0d8 Biofunctionalization for DNA detection This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement No 965643. See www.photo-sens.eu for more information.", "label": "poster"}
{"text": "Visualising the Student Journey Designed as an aid to examiners at Higher Education institutions, the Student Journey tool shows individual student\u2019s progress throughout their programme. Three co-ordinated views [1] allows an overview, with detail of individual modules on demand. The tool also builds-in institutional regulations to make recommendations for the student\u2019s outcome. Repeat Year / Semester 3 2:2 2:1 1 Start Semester 1 Semester 2 Semester 3 Semester 4 Semester 5 Semester 6 Final 3 2:2 2:1 1 SC2 3rd Year (Award) \uf2f9 Year Group (2017/18) Computer Science \uf2f9 Programme Student A \uf2f9 Student 0 10 20 30 40 50 60 70 80 90 100 110 120 >= 40% < 30% Supp. Work Pass Number of Credits Step 1: Select a Student to see the overview. The Regulations view shows, in one bar plot, the possibility of a student progressing or receiving their award. Under most regulations if the red column is present, the student is unable to progress. Otherwise the must meet or exceed the Pass or Supplementary Work levels. Step 2: Click on the timeline to focus on an academic year. Figure 1: Timeline View Figure 3: Regulations View Cameron Gray Dave Perkins m Special Circumstances are highlighted by severity and shown in the appropriate semester. IED-3064 0% ICP-3036 7% ICP-3099 8% Figure 2: Module Detail View Semester 5 Semester 6 UXS-3071 65% @ Student achievement is shown as a coloured gauge. Red represents a failing result. . The Module Header block is proportional to the credit weighting. @ For each student, the tool produces a recommended action based on applicable regulations. 2 Orange coloured gauge lines represent a condonable result under institutional regulations. @ Green coloured gauges represent a passing result. The Module Detail view is a modi\ufb01ed Sankey Diagram [2] to show both structure and achievement for the student. The inclusion of coloured gauges provides Pre-Cognitive Processing [3] by viewers. [1] Roberts, J.C. \u201cState of the art: Coordinated & multiple views in exploratory visualization\u201d. In: Coordinated and Multiple Views in Exploratory Visualization, 2007. CMV\u201907. Fifth International Conference on, pp. 61\u201371. IEEE. [2] P. Riehmann, M. Han\ufb02er and B. Froehlich, \"Interactive Sankey diagrams\", IEEE Symposium on Information Visualization, 2005. IEEE. This tool was trialled during the 2017/\u201918 Final Award Board of Examiners\u2019 meeting within Bangor\u2019s School of Computer Science. It met with general approval and scored 79.65/100 using the Software Usability Scale. ICP-3042 80% [3] Ware, C., 2012. Information visualization: perception for design. Elsevier. School of Computer Science & Electronic Engineering UXS-3041 33%", "label": "poster"}
{"text": "VINEYARD INNOVATIVE TOOLS BASED ON THE INTEGRATION OF EARTH OBSERVATION SERVICES AND IN-FIELD SENSORS A single-entry point solution for wine producers aiming to boost vineyards\u2019 sustainability The project is developing innovative vineyard management solutions, integrating and improving existing solutions coupling satellite imagery with in-field sensors to increase the resolution and reliability of satellite information applied to the viticulture sector and specific wine-business operations. VitiGEOSS uses European Open Earth Observation Services (EOS) for the improvement of agriculture business operations at an economic, environmental and local level. VitiGEOSS goal is to contribute to a responsible production of wine, minimising the use of chemicals and offering tools for a better management and a greater sustainability www.vitigeoss.eu @vitigeoss_EU info@vitigeoss.eu CONTACT US: Rosa Araujo Eurecat, Spain Project Coordinator Phenological monitoring Automated system to better plan and organise the whole vineyard management. Weather & climate forecast Robust weather & climate forecast for decision making processes in the wine sector. Business & sustainability Resource optimiser and planner service capable to plan best timing for field operations. Disease management Forecasting the disease evolution to optimise the treatments and resources used. Crop status Satellite imagery for optimising irrigation, sampling or selective harvesting. This project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement No. 862192 Consortium", "label": "poster"}
{"text": "The Echelle Visualization Tool (Working Title) Bryson Stemock (bstemock@nmsu.edu), New Mexico State University Purpose Status This project is inspired by the Keck Observatory HIRES Echelle Format Simulator. Community Survey to get YOUR input The Echelle Visualization Tool (EVT) will allow ARCES users to visualize their raw data before and during observing runs. The EVT will accurately display the position of each echelle order and each spectral line of interest as it will appear on the CCD. This will provide an intuitive visual aid as observers check their incoming data as the night wears on; an important asset when our brains our tired at odd hours of the night and morning. Source: Sarah Kovac and Candace Gray \u25cfCode foundation written using gratings; will be adapted to mimic ARCES as development progresses \u25cfDisplays blaze wavelength and free spectral range for each echelle order \u25cfCan identify unique wavelength ranges vs. wavelengths that are contained in multiple orders \u25cfTakes an input spectral line list and displays the locations of each given line everywhere it is present in the echelle exposure \u25cfCode written to allow for relatively simple adaptation if/when ARCES is replaced someday The purpose of this poster is to gather input from the APO community to inform the direction of the EVT\u2019s development. Does this seem like a tool that you would use? What features would make the EVT a tool that you would use regularly? If you have any thoughts on how to make the EVT more useful to ARCES users, please take 3-5 minutes to \ufb01ll out a survey using this link: https://forms.gle/K3iGauGrBq6amY8X9. Keck Observatory HIRES Echelle Format Simulator (link below)", "label": "poster"}
{"text": "Explore, observe, design Put three or four elastic bands around a tub, box or jar. Now explore ways to make different sounds. You could compare wide bands and thin bands \u2013 which produces a higher pitched note? What happens to the note when you stretch a band? Organise your selection of elastic bands into order \u2013 from high pitched to low to create a musical instrument. Hint \u2013 a tub often works better than a box because a box crumples. Draw a diagram and write instructions so that someone else can make an instrument that produces the same notes. Dogs can hear sounds that humans can\u2019t. A dog whistle produces a whistling sound that is too high pitched for human ears. Elephants communicate with each other using \u2018rumbles\u2019. These are sounds that are too low pitched for our ears to pick up! Can you make Can you make music with elastic music with elastic bands? bands?", "label": "poster"}
{"text": "Which types of terms become more prevalent, persistant, and adapt th e most? Which terms maintain semantic stability and which have multipl e variations? How can topic modelling and word embedding help to identify terms, an d t o analys e narrativ e structure s a nd semantic changes in specialised texts? Besides Latin calques, transliterations, and borrowings, what are othe r method s o f creatin g neologisms ? A re there limits to neology? Research questions Methodology The starting point of the research is the question about the peculiarities of the vocabulary in medieval French in mathematical texts during the Middle Ages. The goal of the study is to identify the mathematical terminology, focusing on the analysis of neologisms, diachronic, diatopic, diaphasic variations, semantic links, lost notions, and hapax legomena. The research relies on a corpus composed of texts from three out of four disciplines of the quadrivium: arithmetics, geometry and astronomy. The texts used are in edited and manuscript forms. MATHEMATICS VOCABULARY IN MIDDLE FRENCH (13th-16th centuries) Summary Results and conclusion IMAGES : NICOLAS DU PUY, PETIT COMPOST EN FRANCOYSS Corpus compilation. It involves the collection of edited and transcripted manuscripts. NLP analysis. We use topic modelling to analyse the narrative structure an d wor d embeddin g t o detec t semant ic peculiarities. Linguistic analysis. By means of the study of identified occurrences in ou r corpus . Dua l approach : linguisti c c o-tex t o f occurrence s an d narrati ve context of their appearance. This research focuses on under-studied elements in medieval linguistics - neology and terminological variations. In addition to the traditional textometric approach, we experiment with the use of computational techniques. Consequently, the novelty of the work lies in the examination of the discipline\u2019s under-studied phenomena through non- traditional methods.", "label": "poster"}
{"text": "Michel Electron Reconstruction Using a Novel Deep-Learning-Based Multi-Level Event Reconstruction in ICARUS Yeon-jae Jwa on behalf of ICARUS Collaboration 1. Muon Decay-at-rest and Michel Electrons 2. Michel electrons in ICARUS Liquid Argon Time Projection Chamber 3. Deep-Learning based event reconstruction 4. Michel electron selection in ICARUS \u25cfMichel electrons, produced by the decay-at-rest of cosmic-ray muons, have a well understood energy spectrum ranging up to ~50 MeV. \u25cfMichel reconstruction demonstrates the detector\u2019s capability in low-energy electron reconstruction. \u25cfICARUS is 600T Liquid Argon Time Projection Chamber (LArTPC) situated on the Fermilab beamline, receives abundant cosmic-ray muons. \u25cfThe energy loss of Michel electrons in argon has two contributing parts; electron ionization and photon radiation. Ionization Radiation Candidate Michel is \u25cfWithin 3 cm distance to a track \u25cfAttached at the end of the track \u25cfAt least 20 reconstructed voxels Candidate Michels are matched to true Michels. Primary ionization is de\ufb01ned after the selection by \ufb01nding the closest cluster to the parent muon (using DBScan.) 5. Michel energy reconstruction MC sample: BNB+Corsika simulation, Data sample: on-beam Run2 6. References [1] Laura Domin\u00e9. (2023), \u201cDeep Learning based LArTPC Event Reconstruction and Nonmagnetic Muon Sign Determination in the ICARUS Detector\u201d, [Doctoral dissertation, Stanford University.], https://searchworks.stanford.edu/view/14656199 [2] Laura Domin\u00e9, Kazu Terao, \u201cScalable deep convolutional neural networks for sparse, locally dense liquid argon time projection chamber data\u201d, Phys. Rev. D (2020), 102, 1, 012005 [3] SPINE github repository, https://github.com/DeepLearnPhysics/spine Figure 3. U-net network structure for voxel reconstruction. Source: [2]. Figure 1. Theoretically calculated Michel energy. Soure: [1]. Figure 2. Electron stopping power in Argon from tabulated ESTAR database. \u25cfSPINE: framework developed for LArTPC 3D reconstruction. \u25cfVoxels are classi\ufb01ed as: shower-like/track-like/Michel-like/Delta-like/low energy-like using semantic segmentation. \u25cfReconstructed voxels are further grouped to fragments/particles/interactions. Figure 4. Full reconstruction chain in SPINE. Source: [3] \u25cfSummed ADC is translated to energy [MeV] after applying calibrations. (See poster #156 for more details on calibrations). \u25cfFractional energy resolution \u25cbEcorr= (Erec-\u03b2)/\u03b1, where \u03b1: slope, \u03b2: y-intercept from linear \ufb01t of (x,y: Etrue, Ereco). \u25cbEres = (Ecorr-Einit)/Einit, Eres is binned by Einit and \ufb01tted to Gaussian. True Michels Candidate Michels Attached to muon 37042 34582 Matched 32460 32460 Selection ef\ufb01ciency/purity: 87.63 %/93.86 % See poster #280 for more details on SPINE. See poster #108, #156 #280, for more analyses using SPINE. ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress ICARUS Work In Progress 7. Acknowledgement This work was supported by the Department of Energy, Contract DE-AC02-765F00515.", "label": "poster"}
{"text": "Heterosynaptic plasticity rules induce small-world network topologies James McAllister, John Wade, Cian O\u2019Donnell Intelligent Systems Research Centre, Ulster University Introduction Heterosynaptic plasticity is a form of \u2018off-target\u2019 synap- tic plasticity where unstimulated synapses change strength. Here we propose that one purpose of heterosynaptic plastic- ity is to encourage small-world connectivity [6, 7]. We com- pare different plasticity rules in abstract weighted graphs, finding that they yield distinct network architectures. Heterosynaptic plasticity Heterosynaptic plasticity is where synapses that were not directly activated undergo weight changes. Figure 1. Illustration of homosynaptic and heterosynaptic plasticity It can assume either a cooperative or competitive role in the alteration of synaptic weights (Figure 2). Cooperative Competitive Figure 2. Cooperative (left) and competitive (right) directions of weight change in heterosynaptic plasticity Heterosynaptic plasticity can operate locally on single den- drites at neighbouring spines, or across neurons and whole networks [4]. Method: Heterosynaptic plasticity network model Figure 3. Cases for weight updates in model Each edge is either (1) between two active nodes , (2) between one active and one inactive node, or (3) between two inactive nodes . Based on these cases, we define the update rules: R1 = \u001a wi,jn+1 = wi,jn + \u03b71(1 \u2212wi,jn) Case (1) wi,jn+1 = \u03b72wi,jn otherwise \u001b R2 = \uf8f1 \uf8f2 \uf8f3 wi,jn+1 = wi,jn + \u03b31(1 \u2212wi,jn) Case (1) wi,jn+1 = \u03b32wi,jn Case (2) wi,jn+1 = \u03b33wi,jn, Case (3) \uf8fc \uf8fd \uf8fe R3 = \uf8f1 \uf8f2 \uf8f3 wi,jn+1 = wi,jn + \u03ba1(1 \u2212wi,jn) Case (1) wi,jn+1 = wi,jn + \u03ba2(1 \u2212wi,jn) Case (2) wi,jn+1 = \u03ba3wi,jn, Case (3) \uf8fc \uf8fd \uf8fe where R1 is a homosynaptic rule, and R2 and R3 are versions of competitive/cooperative heterosynaptic rules. \u03b7i, \u03b3i and \u03bai are learning parameters. We set \u03b71 = \u03b31 = \u03ba1 = 0.2 \u03b72 = 1 \u2212\u03b71 = 0.8 \u03b72 = \u03b33 = \u03ba3 = 0.8 \u03b32 = 1 \u2212\u03b31/2 = 0.9 \u03ba2 = \u03ba1/2 = 0.1 Method: Activity patterns We define the activity patterns of the network based on different Beta distributions (with varying parameters \u03b1, \u03b2). This determines the probability of each node being active. Network synchrony, firing rates, spike bursts and synaptic weights follow a log-normal distribution (Fig 4) [3], which we can partially replicate with beta distributions (Fig 5 blue line), as well as examine other less realistic activity patterns. Figure 4. Log-normal distribution of neural activity (Petersen & Berg, 2016) Figure 5. Example Beta distributions \u03b1 = 1.5, 4, 4; \u03b2 = 4, 1.5, 4 Method: Graph theory measures Weighted clustering coefficient: \u02dcC = Z 1 0 Ct dt where Ct = C(At) for At ij = 1 if wij \u2265t and 0 otherwise. C(i) = |{ejk : vj, vk \u2208Ni, ejk \u2208E}| ki(ki \u22121) Average shortest path length (Dijkstra\u2019s algorithm) L = 1 n(n \u22121) X i,j\u2208V i\u0338=j dij Small-world measure \u2193 Small-world topologies A small-world network [7] has high degrees of clustering & low average shortest path length. \u03c3 = C/Crand L/Lrand > 1 Results Below is a simulation of how the network characteristics evolve under the homosynaptic (R1) and heterosynaptic (R2 & R3) plasticity rules over 100 timesteps. Figure 6. Graph theory measures for the three rules (N = 50 nodes) Given the probability distribution of activity, we can find a closed form solution for the weight matrix, which saves numerical simulations: R1: w\u221e i,j \u2248 \u03b71pij 1 \u2212(pij \u2212pij\u03b71 \u2212pij\u03b72 + \u03b72) R2: w\u221e i,j \u2248 pij\u03b31 1 \u2212(pij(1 \u2212\u03b31 \u22122\u03b32 + \u03b33) + qij(\u03b32 \u2212\u03b33) + \u03b33) R3: w\u221e i,j \u2248 (pij(\u03ba1 \u22122\u03ba2) + qij\u03ba2) 1 \u2212(pij(\u22121 \u2212\u03ba1 + 2\u03ba2 + \u03ba3) + qij(1 \u2212\u03ba2 \u2212\u03ba3) + \u03ba3) where pi,j is the probability of node i and node j being active, and qi,j is the probability of node i or node j being active. Figure 7. Weight matrices for example network of 20 nodes Results continued Small-world measures across network sizes Figure 8. Small-world measures across different sizes of networks Beta distributions activity & small-world measures Figure 9. Average small-world measures across different activity distributions (N=100) Distribution of ", "label": "poster"}
{"text": "Inferring biased allele expression across the genome Kimberly C. Olney1, Line Sko?e2, Ramus Nielsen3, Melissa Wilson Sayres1,4 1School of Life Sciences, Arizona State University, Tempe, Arizona 2Bioinforma PFSAs > PFCAs. Compared to 1% PAC the biochar derived from waste timber (WT-BC) showed 30 to 40% total retention for shorter chain PFAS and 50% for longer chain PFAS. The sludge derived biochar (SL-BC) performed comparable better, with total retention for shorter chain PFAS in the range of 60 to 70% and 70 to 90% for longer chain PFAS. The increase of the amount of biochar mixed into the soil from 1 to 4% led to 5 to 10% higher PFAS retention. Figure 3 \u2013PFAS stabilization [%] compared to the lysimeter amended with 1% PAC. Green shade identifies shorter chain and red shade longer chain PFAS. \u2022 PFAS contaminated hot spots are vulnarable to a changing rainfall and irrigation events. \u2022 Sludge derived biochar showed prom", "label": "poster"}
{"text": "0.0 0.1 0.2 0.3 10 12 14 16 18 20 22 C\"PEAK /pF Time /h Primary drying 0.244 pF \u22612 g water Drying rate (dm/dt) ~ 0.3 g/h DRIED PRODUCT RESISTANCE (RP) DETERMINATION o C\"PEAK from TVIS is proportional to the amount of ice; therefore it is estimated for drying rate (dm/dt) o Partial pressure of ice (PICE) and condenser (PCONDENSER) calculated from temperature of ice (TICE) and condenser (TCONDENSER) by using Clausius- Clapeyron derived equation -70 -60 -50 -40 -30 10 12 14 16 18 20 Temperature/oC Time / h Temperature of ice (TICE) Temperature of condenser (TCONDENSER) Shelf temperature (TSHELF) The Application of Through Vial Impedance Spectroscopy (TVIS) for Optimization Freeze-Drying Process Yowwares Jeeraruangrattana and Bhaskar Pandya Leicester School of Pharmacy, Faculty of Health and Life Sciences, De Montfort University Supervisors: Professor Geoff Smith and Dr Irina Ermolina TVIS TECHNOLOGY In-line monitoring system for the freeze drying process consisting of: oFreeze-drying vial with external electrodes oPass through for cabling oExternal Impedance spectrometer. TVIS TECHNOLOGY PRINCIPLE Process analytical technology based on impedance spectroscopy o Electrical impedance determines the ability of materials to conduct electricity under an applied voltage . o Impedance is a function of dielectric and conductive properties and therefore the physical state of vial and its contents. o Principal parameter effecting measured impedance is resistance/conductivity of sample within the vial. o Changes in electrical parameters mirror the condition of the sample throughout the lyophilisation process. o The capacitance spectrum is related to the resistance/ conductivity and capacitance of the vial contents. o Data viewing software (LyoView \u2122) identifies the peak frequency (FPEAK) and the peak amplitude (C\u02baPEAK) in the imaginary part of the capacitance spectrum o FPEAK can be used to monitor phase behaviour (ice formation, glass transitions) and product temperature o C\u02baPEAK can be used to monitor the amount of ice remaining during primary drying, from which the drying rate and the end point may be determined. TVIS ADVANTAGE 1.Non-invasive, real time full cycle lyophilisation monitoring including : o Cooling rate, Freezing and Annealing o Primary and Secondary Drying end point 2. Optimization of the primary drying process by: o Heat Transfer Coefficient (KV) Determination o Dried Product Resistance (RP) Determination 3. Can be applied in standard freeze dryers 4. Integrated, bench top, single vial, TVIS enabled analytical freeze dryer \u201cNon-invasive, real time lyophilisation process monitoring would increase process understanding and accelerate development of stabilized biopharmaceutical formulations at room temperature.\u201d 101 102 103 104 105 106 -0.5 -0.4 -0.3 -0.2 -0.1 0 Frequency (Hz) C'' / pF Freezing 24.1 oC 12 oC -5.7 oC -24.3 oC 101 102 103 104 105 106 -0.3 -0.2 -0.1 0 0.1 Frequency (Hz) C'' / pF 11 h 12 h 13 h 15 h 14 h 17 h 16 h 18 h 19 h Primary Drying TVIS APPLICATIONS HEAT TRANSFER COEFFICIENT (KV) DETERMINATION o The product temperature (TPRODUCT) derived by TVIS is one of the parameters needed for KV determination o Sublimation rate or drying rate (dm/dt) is estimated by TVIS \ud835\udc3e\ud835\udc3e\ud835\udc49\ud835\udc49= \ud835\udc51\ud835\udc51\ud835\udc5a\ud835\udc5a \ud835\udc51\ud835\udc51\ud835\udc51\ud835\udc51\u00d7 2844 \ud835\udc3d\ud835\udc3d\u0209 \ud835\udc54\ud835\udc54\u22121 0.00045\ud835\udc5a\ud835\udc5a2 \ud835\udc47\ud835\udc47\ud835\udc46\ud835\udc46\ud835\udc46\ud835\udc46\ud835\udc46\ud835\udc46\ud835\udc46\ud835\udc46\ud835\udc46\ud835\udc46\u2212\ud835\udc47\ud835\udc47\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43\ud835\udc43 TPRODUCT and dm/dt from TVIS KV determination 0.00 0.02 0.04 0.06 0.08 0.10 10 12 14 16 18 20 Drying rate (g/h) Time /h RP determination \ud835\udc45\ud835\udc45\ud835\udc5d\ud835\udc5d= \ud835\udc43\ud835\udc43\ud835\udc3c\ud835\udc3c\ud835\udc3c\ud835\udc3c\ud835\udc3c\ud835\udc3c\u2212\ud835\udc43\ud835\udc43\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36\ud835\udc36 \ud835\udc51\ud835\udc51\ud835\udc5a\ud835\udc5a \ud835\udc51\ud835\udc51\ud835\udc51\ud835\udc51 \u0209 3.8 \ud835\udc50\ud835\udc50\ud835\udc50\ud835\udc502 0 10 20 30 40 50 60 70 0 10 20 30 40 50 60 70 80 0 30 60 90 Heat radiation (% of total heat transfer) Over all heat transfer Coefficient (O.H.T.C) (w/m-2k-1) Pressure (Pa) O.H.T.C (water exp.) O.H.T.C (ice exp.) Heat radiation (water exp.) Heat radiation (ice exp.) Kv from TVIS dm/dt from TVIS Figure 2. KV values for 10 mL tubing vials (Br\u00fclls et al. 2002) Kv from TVIS = 37 Figure 3. The ratio of Rp and dry thickness as the function of dry thickness References 1. BR\u00dcLLS, M. and RASMUSON, A.", "label": "poster"}
{"text": "Kontakt Dr. Andrea Beyer Institut f\u00fcr Klassische Philologie daidalos-projekt@hu-berlin.de Mastertitelformat bearbeiten Fachspezifische Methodenkompetenz Digital \u2013 Data \u2013 AI Literacy als Teil von Forschungskompetenz in der Klassischen Philologie User Story: Wie findet man, was nicht explizit im Text genannt wird? (DFG-Heisenberg-Projekt \u201eFormen des ,Vergessens\u2018 in der r\u00f6mischen Literatur\u201c, Prof. Dr. Verena Schulz, KU Eichst\u00e4tt-Ingolstadt) \uf0d8Hintergrund: Geschichtsschreiber erw\u00e4hnen bestimmte Ereignisse nicht, obwohl sie diese aufgrund ihrer Relevanz erw\u00e4hnen sollten, bspw. kommt bei Cassius Dio die Konferenz von Luca 56 v. Chr. nicht vor, Cicero l\u00e4sst bspw. Crassus weg. \uf0d8Konkrete Forschungsfrage: Gibt es eine kanonische Art (Ort, Personal, Thema), diese Konferenz zu erw\u00e4hnen? Welche Kontexte sprechen f\u00fcr eine Erw\u00e4hnung, welche dagegen? \uf0d8Fach- und fallspezifische Digital Literacies: \u2212 Digital Literacy: z. B. Datenformate (DOCX, TXT, HTML) verstehen, Lizenzrechte kennen, Ressourcen nachnutzen \u2212 Data Literacy: z. B. Daten zusammenstellen (Korpusauswahl), Korpussuchwerkzeug nutzen, Umgang mit Datenvisualisierungen \u2212 AI Literacy: z. B. Lemmatisierung und NER kennen, Vektorisierung von Tokens verstehen, Ergebnisse kritisch analysieren und Erkl\u00e4rungen f\u00fcr Ergebnisse finden (Basis: Fachkompetenz) Daidalos: Wie viel Methodenkompetenz braucht ein User? Humboldt-Universit\u00e4t zu Berlin Klassische Philologie, Korpuslinguistik, Computer- und Medienservice Andrea Beyer, Konstantin Schulz \u201eWie soll ich ein Forschungsvorhaben entwickeln, bei dem der Einsatz von NLP- Methoden sinnvoll w\u00e4re, wenn ich diese Methoden gar nicht kenne?\u201c Forschungskompetenz Verstehen Anwenden Bewerten Gestalten Digital Literacy Unterschied DOCX & TXT DOCX in TXT umwandeln Problemstellen in TXT identifizieren TXT fallspezifisch modifizieren Data Literacy Annotationen einordnen Annotationen interpretieren Fehlerhafte Annotationen reflektieren Annotationen in HTML ver\u00e4ndern AI Literacy Konzept NER: mehrere Tagger pro Sprache NER-Ergebnisse vergleichen NER-Fehler systematisch auswerten NER-Tagger durch Feedback weiterentwickeln Fallspezifische Umsetzung eines Kompetenzstufenmodells mit Kompetenzdeskriptoren f\u00fcr die digitalen Teilkompetenzen von klassisch-philologischer Forschungskompetenz Texte Kritische Editionen Literatur Sprach- erwerb \u00dcber- setzungen Kom- mentare Kultur: Interdepen- denz, Modelle Literatur: Intertextua- lit\u00e4t, Wirkung Text: Autor, Genre Sprache: Stil, Klang Forschungsfelder der Klassischen Philologie Sprachen: Latein und Altgriechisch NER Sentiment Topics Embeddings \u2026 POS Preprocessing orange = Forscher oder Forscherin, blau = Daidalos 1. Kontaktaufnahme & Basisinfos, 2. Erstgespr\u00e4ch Forschungsfrage, 3. Forschungsmaterial, 4. NLP & Ergebnisse, 5. Zweitgespr\u00e4ch Ergebnisdiskussion, 6. ggf. Iteration 3-5, 7. Kooperative Publikation 1. 2. 3. 4. 1. 5. 4. 7. 6. Ablauf eines Forschungstandems Designentwurf der Daidalos-Benutzeroberfl\u00e4che f\u00fcr NLP-gest\u00fctzte Forschung: User spezifizieren ihre Forschungsfrage, w\u00e4hlen ein Textkorpus und planen dessen Verarbeitung. Forschen ohne Code Exemplarisches Jupyter-Notebook mit Programmiercode zur Implementierung von Lemmatisierung und Named Entity Recognition f\u00fcr altgriechische Literatur Forschen mit Code & Lernen anhand eines kuratierten Workflows Interaktive \u00dcbungen mit automatischem Feedback zum Kompetenzaufbau im Sinne der AI Literacy als Teil der angestrebten Digital Literacies, implementiert mit H5P Lernen zum Ausbau der Forschungskompetenz Workshops & Colloquia", "label": "poster"}
{"text": "Sensitivity of a middle atmosphere GCM to consistent scale-interaction of parameterized orographic gravity waves Benjamin Wolf, Erich Becker \u2013 Leibniz-Institut of Atmospheric Physics e.V. at Rostock University, email: wolf@iap-kborn.de Summary We find that the circulation in the middle atmosphere is significantly sensitive to the details of the OGW scheme. In particular, the vertical diffusion induced by saturation of OGWs has a considerable impact on the polar night jet during northern hemispheric winter, both by the diffusivity itself and by the secondary effect due to an upward shift of the breaking levels of NGWs. In turn, these changes affect the summer mesopause region by the interhemispheric coupling mechanism. A strong sensitivity of the mesosphere to GWs has also been found in the simulations of sudden stratospheric warmings (McLandress et al. [2012]). The damping of OGWs by boundary layer turbulence and the energy deposition by OGWs are found to be of minor importance. Model Description Difference to conventional parametrizations Classical OGW scheme and extensions \uf06c Excitation with subgrid scale orographic perturbation field and resolved near-surface wind \uf06c + Wave equations allow long vertical wavelengths \uf06c Lindzen saturation hypothesis (Lindzen [1981]): convective instability leads to turbulent vertical heat and momentum diffusion of OGWs \uf06c + Wave propagation according to WKB-Approximation: total turbulent vertical diffusion affects OGWs \uf06c Momentum deposition, drag, by OGWs (OGWD) affects the resolved flow \uf06c + Turbulent diffusion due to saturation of OGWs affects all other scales (resolved large-scale flow, NGWs) \uf06c + Energy deposition by OGWs Zonal-mean model climatology from December to February (DJF). (a) Temperature (K, colors) and residual mass streamfunction (contours for -100, -10, -1, +0.001, +0.01, +0.1, +1, +10 +100 Mt s-1) . (b) Zonal wind (m s-1, colors) and complete Eliassen-Palm-Flux (EPF) divergence, including resolved waves and parameterized GWs (contours for -60, -40, -20, -10, -5, 5, 10, 20, 40, 60, 80 m s-1d-1) References M.J. Alexander et al., A Review of Recent Developments on Gravity Wave Effects in Climate Models and the Global Distribution of Gravity Wave Momentum Flux, Quarterly Journal of the Royal Meteorological Society, 2009 E. Becker and U. Burkhardt, Nonlinear Horizontal Diffusion for GCMs, Monthly Weather Review, 2007 E. Becker and C. McLandress, Consistent scale interaction of gravity waves in the Doppler-spread parameterization, Journal of the Atmospheric Sciences, 2009. R. Kn\u00f6pfel and E. Becker, An idealized radiative transfer scheme for use in a mechanistic general circulation model from the surface up to the menopause region, Journal of Quantitative Spectroscopy Radiativ Transfer, 2011 H. K\u00f6rnich and E. Becker, A simple model for the interhemispheric coupling of the middle atmosphere circulation, Advances in Space Research, 2010 R.S. Lindzen, Turbulence and Stress Owing to Gravity Wave and Tidal Breakdown; Journal of Geophysical Research, 1981 N.A. McFarlane, The Effect of Orographically Excited Gravity Wave Drag on the General Circulation of the Lower Stratosphere and Troposphere, Journal of the Atmospheric Sciences, 1987 C. McLandress et al., Dynamical control of the mesosphere by orographic and non-orographic gravity wave drag during extended northern winters of 2006 and 2009, Journal of the Atmospheric Sciences, 2012 General influence of parameterized orographic gravity waves Zonal-mean model climatology from December to February (DJF). (a) differences in the orographic wave drag, OGWD (m s-1d-1, colors) between the new and the conventional parametrisation and OGW- induced vertical diffusion coefficient in the control run (contours for 1, 4, 8, 15, 30 m-2s-1d-1) for DJF. (b) Differences in the complete Eliassen-Palm-Flux (EPF) divergence (m s-1d-1, colors) and complete EPF divergence in the control run (contours for - 60, -40, -20, -10, -5, 5, 10, 20, 40, 60, 80 m s-1d-1). OGW", "label": "poster"}
{"text": "European XFEL Data Analysis Workflows for SFX and beyond Oleksii Turkot, Fabio Dall\u2019Antonia, Richard J. Bean, Juncheng E, Hans Fangohr, Danilo E. Ferreira de Lima, Sravya Kantamneni, Henry J. Kirkwood, Faisal H. M. Koua, Adrian P. Mancuso, Diogo V. M. Melo, Adam Round, Michael Schuh, Egor Sobolev, Thomas A. White*, Raphae\u0308l de Wijn, James J. Wrigley, and Luca Gelisio European X-ray Free Electron Laser, Schenefeld, Germany. European XFEL GmbH, Fabio Dall\u2019Antonia, Holzkoppel 4, 22869 Schenefeld, Germany, Phone +49 40 8998-6411, fabio.dall.antonia@xfel.eu www.xfel.eu The SPB/SFX instrument [1] at the European XFEL (EuXFEL) provides a portfolio of experiment techniques for the structural elucidation of biomolecules, relevant to the life science domain - among those single particle imaging (SPI), small-angle X-ray scattering (SAXS) and serial femtosecond crystallography (SFX). All of these can exploit the MHz repetition rate of both the FEL accelerator and synchronised megapixel detectors in order to capture dynamic processes in the nanosecond time regime. Due to the ultra-short, ultra-brilliant laser pulses combined with rapid sample re-supply in e.g. liquid jets, SFX can be applied to micrometer-sized crystals, producing millions of almost damage-free single-shot diffraction images. Conclusions and Outlook References [1] A. Mancuso et al. (2019). J. Synchrotron Radiat. 26, 660. DOI: 10.1107/S1600577519003308 [2] T. A. White et al. (2012). J. Appl. Cryst. 45, 335. DOI: 10.1107/S0021889812002312 [3] O. Turkot et al. (2023). Crystals 13 (11). DOI: 10.3390/cryst13111533 [4] https://github.com/European-XFEL/DAMNIT Acknowledgements This work was partially supported by the consortium DAPHNE4NFDI in association with the German National Research Data Infrastructure (NFDI) e.V. NFDI is financed by the Federal Republic of Germany and the 16 federal states and the consortium is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) - project number 460248799. You are most welcome to contact the EuXFEL Data Analysis Group at da@xfel.eu. HALRIC Meeting 2024 Due to the peculiar pulse structure, a vast number of data sources and specifics of custom- built MHz pixel detectors, EuXFEL data are both large and complex. Accessible and reproducible data analysis workflows require software that can manage the complexity of data and provide low-barrier entry points for scientists. EXtra-Xwiz is a SFX-workflow-specific pipeline tool to interface CrystFEL with the preprocessing of EuXFEL data and distributed computing on HPC clusters. Other pipelines at EuXFEL, such as for X-ray photon correlation spectroscopy (XPCS), exist. DAMNIT follows a generic philosophy for data extraction from primary experiment sources as well as embedded processing software, and can be used for any experiment technique at EuXFEL, including SFX, SAXS and SPI. We are working on better support for the NeXus data standard, which will further enhance interoperability between software as well as between photon science facilities CrystFEL [2] is a widely used software suite that specialises on SFX data processing. EXtra-Xwiz [3] is a tool that manages data processing pipelines using CrystFEL, streamlining aspects such as the ingestion of EuXFEL-format data files and the scheduling of distributed computing on the HPC cluster. It can be integrated to the DAMNIT software [4] for metadata extraction and data analysis workflow management. B SFX at EuXFEL \u2013 i. p. the SFB/SFX upstream interaction region in vacuum \u2013 exploits a huge number of \u201cshots\u201d at the sample which is delivered in a jet. The X-ray probe exhibits a discontinuous 10 Hz train structure with MHz pulse repetition. The crystal hit rate is mostly below 10%. Peak finding and indexing with indexamajig (right, step 2) allows to distinguish between Bragg diffraction images and useless image frames. DAMNIT is driven by high level Python code and presents run-based primary metadata as well as processing results", "label": "poster"}
{"text": "Start Here: On Ramps for the VIVO Project Mike Conlon, mconlon@duraspace.org; Julia Trimmer, julia.trimmer@duke.edu; Graham Triggs, gtriggs@duraspace.org Project Managers Ask Questions Join bit.ly/vivo-community and ask away! Read the Implementation Guide VIVO has a guide to implementation. See bit.ly/vivo-planning Work with Data Providers Speak with data providers about VIVO and your project. Share your interest in research discovery, open scholarship, and linked data Join Outreach and Engagement Calls Monthly calls for sharing outreach and engagement experiences bit.ly/vivo-oaeig Help us Grow The VIVO Registry bit.ly/vivo- registry lists all VIVO sites. Add your site. Developers Install VIVO github.com/vivo-project Read the Documentation bit.ly/vivo-docs Ask Questions Join bit.ly/vivo-tech and ask away! Join Developer Calls See bit.ly/vivo-dig Develop Ontology Ontologies used by VIVO are developed using open source processes. See github.com/openrif Review/Open JIRA tickets See bit.ly/vivo-jira Become a Committer See bit.ly/vivo-committers Faculty Learn about VIVO The VIVO Book is available here: bit.ly/vivo-book Join All Group Get VIVO Updates, a weekly summary of the VIVO news. bit.ly/vivo-all Advocate for VIVO Talk to fellow faculty members and administrators about VIVO and the case for open scholarship, research discovery, and linked data Participate in your VIVO Work with your local VIVO project to generate value for faculty. Ask us about your local project. mconlon@duraspace.org gtriggs@duraspace.org Participate in the VIVO Project The VIVO wiki bit.ly/vivo-wiki has more info Members Consider membership Financial support for VIVO comes from VIVO membership in Duraspace. See vivoweb.org/membership Become a member Not a member? Becoming a member is simple. See bit.ly/dura-join Join All Group Get VIVO Updates, a weekly summary of the VIVO news. bit.ly/vivo-all Attend the Summit Premium members are invited to the Duraspace Summit held in Washington DC each March. See bit.ly/dura-summit Participate in Governance Serve on Leadership and/or Steering. See VIVO charter bit.ly/vivo-charter Service Providers Learn About Registered Service Provider (RSP) Program See bit.ly/dura-rsp Join All Group Get VIVO Updates, a weekly summary of the VIVO news. bit.ly/vivo-all Become an RSP Questions? Contact Jonathan Markow (jjmarkow@duraspace.org) Help us Grow The VIVO Registry bit.ly/vivo-registry lists all VIVO sites. Add your sites. Ask Questions We want to hear from you. Drop us a note mconlon@duraspace.org, gtriggs@duraspace.org Participate in the VIVO Project The VIVO wiki bit.ly/vivo-wiki has more info VIVO has many on-line resources. Here are some suggestions to help you get started.", "label": "poster"}
{"text": "Double-Active Membranes for a sustainable CO2 cycle DAM4CO\u2082 develops a novel membrane technology for the simultaneous CO\u2082 separation and its photocatalytic conversion to C4-C9 molecules, as renewable fuels. The project will deliver a prototype, designed using the design-build-test-learn approach, for a proof-of-concept validation that will be tested in lab-conditions. The DBTL approach is inherent in each scientific/technological WP of the project. Our objective: Partners: This project has received funding from the European Union\u2019s Horizon Europe research and innovation programme under grant agreement No 101115488. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or European Innovation Council and SMEs Executive Agency (EISMEA). Neither the European Union nor the granting authority can be held responsible for them. WP1: Coordination & Management WP2: Materials Synthesis WP3: Materials Characterization WP4: Membrane preparation & Characterization WP5: Capture with Membranes WP6: Conversion with Membranes WP7: Multiscale Modelling & Life Cycle Assessment WP8: Dissemination & Communication & Exploitation WP9: Portfolio Activities Contacts PROJECT COORDINATOR Dr. Alessio Fuoco, CNR \u2013 ITM E-mail: alessio.fuoco@cnr.it Website: www.dam4co2.eu E-mail: dam4co2@itm.cnr.it Project number: 101115488 Project title: Double-Active Membranes for a sustainable CO2 cycle Project Acronym: DAM4CO2 Granting authority: EISMEA and UKRI Start date: 01/11/2023 Duration: 36 months EU Contribution: 2 975 275.00 \u20ac UK Contribution: 823 176.00 \u00a3 \u2022 Use of non-critical raw materials at any stage of the project \u2022 Greener material and protocols for membrane production \u2022 Development of the next generation membranes for CO2 capture using advanced polymers and MOFs \u2022 Development of photocatalytic membranes using mono and bi-functional catalysts for CO2 conversion into C4-C9 molecules \u2022 Integration of the CO2 management and valorisation processes into a single device \u2022 Design of novel membrane modules CNR (IT) INSTM (IT) ME-SEP (PL) UEdin (UK) PRIMALCHIT (ES) UPV-ITQ (ES) USwan (UK) DAM4CO\u2082, responding to the call \"EIC Pathfinder Challenge: Carbon dioxide and nitrogen management and valorisation\", aims at changing the existing paradigm within separation and utilization of CO\u2082 by coupling membrane and catalytic technologies. https://www.instagram.com/dam4co2/ https://www.linkedin.com/company/dam4co2 https://www.youtube.com/@DAM4CO2_EIC https://twitter.com/dam4co2", "label": "poster"}
{"text": "Introduction \u2022 Radiation oncology physicists spend a lot of time performing and analysing pre- treatment patient-specific QA checks. Given this, we should ensure that our processes are fit for purpose. \u2022 Statistical control methods are suggested best practice for establishing, monitoring and retrospective review of QA processes and results1. These include histograms, control charts and control limits. \u2022 Our department used the installation of two new systems (the Varian Edge & Accuray Radixact) as an opportunity to reflect on and plan our future patient- specific QA processes, with control charts. Data SPC-derived control limit Modality points 2%/2mm 3%/2mm 3%/3mm VMAT (per beam) 61 93.3% 96.9% 99.1% VMAT (composite) 60 95.6% 98.4% 99.5% Tomotherapy 30 84.7% 96.0% 99.0% Radixact 35 98.1% 99.5% 99.8% Application of statistical process control methods in the retrospective review and design of patient-specific quality assurance processes Scott Crowe,1,2,3 Liting Yu,1,3 Samuel Peet,1,2,3 Tanya Kairn,1,2,3 1Royal Brisbane & Women\u2019s Hospital; 2University of Queensland; 3Queensland University of Technology Conclusions \u2022 Control charts allow quantitative review of historical QA data and allow departments to determine tolerance limits specific to their planning, treatment and QA processes. This recommended by TG-2181 as best practice. \u2022 Consider how you record QA data and associated plan and dose information, to facilitate review, and in the future, potentially allow that data to be processed by machine- learning QA prediction tools. \u2022 Specificity and sensitivity testing in detection of simulated errors will be used to identify appropriate action limits. 90 92 94 96 98 100 0 10 20 30 40 50 60 2%/2mm gamma pass rate Quality assurance test case Individual control chart for VMAT QA results Background \u2022 Control charts are used to plot individual QA data points or differences between consecutive data (MR, moving range). \u2022 Control limits can be calculated from the QA data: Control limit = \u0d24x \u22122.66 MR \u2022 Typically calculated for a build phase, e.g., initial 30 results. \u2022 Control limits are tolerance limits and describe expected system performance. QA results beyond limits are assumed to have an assignable cause. Tolerances are distinct from action limits, which are defined by potential clinical impact. References 1.Miften M, et al. Med Phys. 2018;45:53\u201383. 10.1002/mp.12810 Disclosures The authors have nothing to disclose. The study was exempted from ethical review (EX/2021/QRBW/82062). scott.crowe@health.qld.gov.au Poster presented at EPSM 2022. Questions? Ask me! Calculated limit of 95.6% Out of control QA results Average result of 99.1% Methods Results \u2022 Build phase data was not entirely in control for some data, suggesting that there are assignable causes for QA failure. \u2022 For simplicity and conformity between modalities, tolerance limits of 95% (and action level of 90%) using 2%/2mm gamma criteria were preferred by the physics team for future VMAT composite and Radixact QA evaluations. \u2022 Process performance metrics indicate that our planning, dose calculation, delivery and QA processes should reliably produce plans that are able to meet these tolerance limits. Octavius 1500 data collected for 30+ VMAT, Tomo & Radixact plans. Pass rates calculated for multiple sets of gamma criteria pairs. Charts, limits, and process performance characterised for calculated data. Results and plans for ongoing QA discussed in physics team meeting.", "label": "poster"}
{"text": "IN VITRO REGENERATION PROTOCOLS FROM IMMATURE MALE FLOWER BUDS OF BANANA CV. KARPURA CHAKKARAKELI (AAB) AND ASSESSMENT OF GENETIC FIDELITY WITH SSR & ISSR MARKERS M. Viswanath 1* B. V. K. Bhagavan2 K. Ravindra Kumar3 P. Subbaramamma4 M. GirijaRani5 *1 Ph.D Scholar, Department of Fruit Science, College of Horticulture, V.R. Gudem, 2 Principal scientist & Head, 3Scientist, 4Associate professor, 5Senior Scientist & Head Dr. Y.S.R. Horticultural University, Venkataramannagudem \u2013 534101, Andhra Pradesh, India. *Corresponding author\u2019s email:viswahorti123@gmail.com An efficient in vitro propagation protocol has been developed for the first time on direct differentiation of shoot buds from immature male flower buds of banana cv. Karpura Chakkarakeli (AAB). MS media supplemented with 1.0 mgL-1 TDZ + 0.5 mgL-1 IAA + 2 mgL-1 CH was found optimal for per -cent cauliflower-like bodies (CLBs) formation (75.04%), maximum number of CLBs (15.01) explant-1 and minimum number of days (43.54d) taken for CLBs induction. The highest per cent (75.37%) and maximum number (12.78) of shoots proliferated explant-1 within 120 days after culture initiation. The regenerated plantlets rooted better in half MS media supplemented with 0.5 mgL-1 IBA and hardened with 97% survival rate. SSR & ISSR markers were employed to assess the genetic stability of in vitro regenerated and multiplied plantlets of banana cv. Karpura Chakkarakeli (AAB) recorded 100% monomorphic across all the regenerated plants with the mother plant. Plate 1. Different stages of in vitro regeneration in banana cv. Karpura Chakkarakeli (AAB). a Mother plant bearing fruits and male flower bud. b Excised male flower bud. c Reduced male floral bud (6-7cm). d A group of male flowers (hands) used for culture. e Floral explants initiated on MS basal medium supplemented with 1 mgL-1 TDZ + 0.5 mgL-1 IAA + 2 CH. f Clusters of Cauliflower-like-bodies (CLBs). g CLBs converting to shoots. h In vitro shoot clusters i Plantlets ready for hardening. Secondary hardened plantlets. . ur s Plate 2. Morphogenic responses from the immature male flower explants of banana cv Karpura Chakkarakeli (AAB) in T14 treatment A. Responded explant (7 DAI) B. Green colo swollen base (15 DAI) C. Perianth necrosis (20 DAI) D. Formation of Cauliflower-like-bodie (CLBs) (30 DAI) E. Formation of shoot buds (60 DAI) F. Shoot clusters(90 DAI). \uf076Murashige and Skoog\u2019s (MS) media supplemented with 1.0 mgL-1 TDZ + 0.5 mgL-1 IAA + 2 mgL-1 casein hydrolysate was found optimal for per cent cauliflower- like bodies (CLBs) formation (75.04%), maximum number of CLBs (15.01) explant-1 and minimum number of days (43.54d) taken for CLBs induction. \uf076The highest per cent (75.37%) and maximum number (12.78) of shoots proliferated explant-1 within 120 days after culture initiation.The regenerated plantlets rooted better in half MS media supplemented with 0.5 mgL-1 IBA and hardened with 97% survival rate. SSR & ISSR amplified products were 100% monomorphic across all the regenerated plants and mother plant. RESULTS & DISCUSSION \uf0fcMS media supplemented with 1.0 mgL-1 TDZ + 0.5 mgL-1 IAA + 2 mgL-1 CH in 0.25% gel-rite was found optimum for mass production of this commercially important banana cv. Karpura Chakkarakeli (AAB) from IMF buds. CONCLUSION Amplification with SSR & ISSR primers A) Ma-SSR-230 B) UBC 868 300 bp B ABSTRACT INTRODUCTION \uf0d8Karpura Chakkarakeli (AAB), the choicest table cultivar of banana belongs to Mysore subgroup commercially grown in the coastal districts of Andhra Pradesh. \uf0d8Due to its highly recalcitrant nature, excessive phenol compounds, biotic contamination and poor multiplication rate causing the major hindrances for its commercial multiplication through shoot tip explants. \uf0d8Keeping in this view, this study was aimed to examine the potential of male flower explants as an alternate source material for culture establishment, morphogenetic responses and direct organogenesis with different combinations and concentrations of plant ", "label": "poster"}
{"text": "support IL layer metal particle/center Improved electrochemical perfor- mance of Fe-N-C catalysts through ionic liquid modification in alkaline media Thomas Wolker, Ioanna Martinaiou, Ali Shahraei, Gui-Rong Zhang, A. Jan\u00dfen, Stephan Wagner, Natascha Weidler, Robert W. Stark, Bastian J.M. Etzold*, Ulrike I. Kramm Electrochemistry 2018, 24.-26.09.2018, Ulm correspondence: Prof. Dr.-Ing. B.J.M. Etzold email: etzold@tu-darmstadt.de Ernst-Berl-Institut phone: +49 (0) 6151 / 16-29984 Alarich-Weiss-Str. 8 fax: +49 (0) 6151 / 16-29982 D-64287 Darmstadt http: www.etzoldlab.de literature: [1] Y. Nie, L. Li, Z. Wei, Chem. Soc. Rev. 44 (2015) [2] G.R. Zhang, M. Munoz, B.J.M. Etzold, ACS Appl. Mater. Interfaces 7 (2015) [3] G.R. Zhang, M. Munoz, B.J.M. Etzold, Angew. Chem. Int. Ed. 55 (2016) [4] I. Martinaiou, T. Wolker, B.J.M. Etzold, et al., J. Power Sources 375 (2018) Highly active oxygen reduction reaction (ORR) electrocatalysts that are stable under operating conditions are needed in order to enable a widespread commercialization of the fuel cell technology. State-of-the-art ORR catalysts are mostly based on platinum. Due to their high price noble-metal-free alternatives are highly desirable [1]. Carbon-based materials emerge as one of the promising candidates due to their remarkable advantages of low cost, abundant structural variety, tailorable surface chemistry, and good conductivity. Transition metal-nitrogen-carbon catalysts (e.g. Fe-N-C) are considered as one of the most promising representatives of this catalyst class. However, these systems often show a poor stability during electrochemical cycling and therefore still need to be improved in order to replace state-of-the- art noble metal catalysts. Quite recently we have demonstrated that filling the pores of Pt/C catalysts by a minor amount of Ionic Liquid ([BMIM][NTf2], [MTBD][NTf2]) would significantly boost the catalytic activity of Pt/C for ORR [2,3]. This was explained by the fact that the modification led to a new microenvironment around active centers that would prevent the poisoning with oxygenated species. Inspired by this work, herein we transfer this strategy to the Fe-N-C catalysts [4]. \u00a7 Fe-N-C catalysts with and without sulfur were prepared \u00a7 Sulfur addition led to a slightly increased micropore volume \u00a7 Modification of sulfur free catalysts with [BMMIM][NTf2] increased the catalytic ORR- activity in a similar range as sulfur addition \u00a7 The different behavior of the sulfur containing catalyst could be explained by pore blocking effects \u00a7 IL modification could thus be an interesting way to obtain highly active and stable noble- metal free electrocatalysts for fuel cell aplications Introduction Oxygen Reduction Reaction Solid Catalysts with Ionic Liquid Layer (SCILL concept) \u03b1 = 0 \u03b1 = 10% \u03b1: pore filling degree \u03b1 = VIL/Vpore,0 The pores of a catalyst are partially filled with Ionic Liquid to create a new microenvironment around active centers Highly active catalyst needed to overcome sluggish kinetics Selectivity towards 4 e- - pathway desired Conclusions O2 OH- HO2- O2 OH- HO2- 2e- 2e- 4e- O2 H2O H2O2 2e- 2e- 4e- Alkaline Acidic Dicyandiamide Iron acetate Phenanthroline Thermal decomposition 800 \u00b0C Acid leaching 2nd heat treatment Fe-(S)-N-C Sulfur ( ) ( ) Catalyst Synthesis and Modification Fe-(S)-N-C-SCILL Unreactive species Textural Characterization SBET /m2 g-1 SMicropore /m2 g-1 SMesopore /m2 g-1 VPore /cm3 g-1 -S 416 218 201 0.49 +S 442 299 165 0.44 Nitrogen sorption revealed similar textural properties Electrocatalytic Performance IL Modification can cause similar boosting as sulfur Stability can also be improved by IL addition [BMMIM][NTf2] TW, GRZ and BE acknowledge funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement n\u00b0 681719) Acknowledgment + IL", "label": "poster"}
{"text": "CO-CREATING EXERGAMES WITH PARKINSON\u2019S DISEASE PATIENTS T. Savvidis*, E. Konstantinidis*, S. Dias**, V. Zilidou*, E. Romanopoulou*, L. Hadjileontiadis***, P. Bamidis* *Lab of Medical Physics, School of Health Sciences, Aristotle University of Thessaloniki **Faculdade de Motricidade Humana Universidade de Lisboa Lisbon, Portugal ***Faculty of Technology, Aristotle University of Thessaloniki teo.savvidi@gmail.com, evdokimosk@gmail.com, sbalula@fmh.ulisboa.pt, vickyzilidou@gmail.com, evangeliaromanopoulou@gmail.com, leontios@auth.gr, pdbamidis@gmail.com Introduction In this study, the Minimum Viable Product (MVP) model was applied with regards to \u201cMeasure-develop- learn\u201d circle along with its impact on the decision for the development tools and technologies. An example of designing exergames for Parkinson\u2019s disease (PD) patients by considering their valuable feedback [1] and how this influenced low-level technical decisions (changing game engine from 2D Exergames to 3D) are thoroughly discussed. PD Patients feedback Develop Learn/Design Methodology The designing procedure inluded the ivolvement of PD patients in a discussion in which a draft version of the games was presented through storyboards (Figure 1) [1] and followed by a questionnaire. The feedback collected through this process led the developers to design the first game in 2D as part of the wFitForAll web based platform [2][3]. The first 2D prototype game (Figure 2) was presented to the PD patients in an open discussion and a questionnaire has been utilised for the feedback acquisition. The most remarkable point was that although in the design thinking phase the PD patients had reported that they would prefer 2D simple graphics, they were not so enthusiastic but prefered more realistic 3D games. Results The results from the first MVP circle showed that 7/10 patients asked about storyboards/2D would like the abstract/animated design. The second MVP circle leaded to the creation of the Unity 3D prototype. The third MVP circle showed that 3/4 patients asked about the 3D prototype, they liked it more from the 2D. The evaluation process of the second 3D prototype lead us to create more games, 14 in total. Conclusion Using the MVP circles in a spiral way helped us to understand the needs of the PD patients regarding the exergames and develop them more efficiently. The 14 games will be evaluated again in the future during the pilot tests. References 1.S. B. Dias, E. Konstantinidis, J. A. Diniz, P. Bamidis et al., On supporting Parkinson's Disease patients: The i-PROGNOSIS Personalized Game Suite design approach. Computer-Based Medical Systems - IEEE CBMS, Thessaloniki Greece, 2017 2.WebFitForAll platform (www.fitforall.gr). 3.Konstantinidis E, Bamparopoulos G and Bamidis P. Moving Real Exergaming Engines on the Web: The webFitForAll case study in an active and healthy ageing living lab environment, IEEE Journal of Biomedical and Health Informatics, 2016 Acknowledgement The work has been partially supported by the EU H2020-PHC21-2015 \u2018i-PROGNOSIS\u2019 Project (N\u00b0 690494), as well as, the LLM Care (www.llmcare.gr) self-funded initiative that emerged as the business exploitation of the Long Lasting Memories Project originally funded by the ICT-CIP-PSP programme. We thank Parkinson\u2019s disease association (Thessaloniki, Greece) for their support and their contribution on this study. Figure 1. Storyboard Using the Unity3D, the game was re-developed in 3D with realistic graphics and physics in high resolution (Figure 3) . The realistic physics and the high resolution graphics couldn\u2019t be supported by the Android depth sensor, while the \u201cLow Poly\u201d design adopted, which offers faster rendering because of the small amount of polygons of the model. The final 3D prototype (Figure 4) developed following this new and modern style and improves the Frame per second (FPS) and the gameplay. Figure 2. 2D Prototype Figure 3. First 3D Realistic Graphics Figure 4. Final 3D Design Figure 5. Three out of f", "label": "poster"}
{"text": "ORIENTACI\u00d3N Y DECORACIONES ASTRON\u00d3MICAS DE H\u00d3RREOS DEL SUR DE GALICIA Las poblaciones de Beade y Vilaboa Cintia Cabada (1,2), Marta Gonz\u00e1lez (1,3), Ana Ulla-Miguel (1,2), F\u00e1tima Bra\u00f1a (1), Esther P\u00e9rez (1,4), Beatriz Mart\u00ednez (1,5) 1: Grupo de Astronom\u00eda, Astrof\u00edsica, Antropolog\u00eda Cultura y Educaci\u00f3n (A3CE - Universidade de Vigo), 2: Centro de Investigaci\u00f3n Mari\u00f1a (CIM \u2013 GEOMA, Universidade de Vigo), 3: Universidad Internacional Valenciana, 4: IES de Beade, Vigo 5: CPI O Toural de Vilaboa e-mail: marta.gonzalezg@professor.universidadviu.com 5- AGRADECIMIENTOS: Un especial agradecimiento al alumnado colaborador del colegio CIP O Toural de Vilaboa y el instituto IES Beade de Vigo. Tambi\u00e9n agradecemos el apoyo del Servicio P\u00fablico de Empleo Estatal (SEPE) y de la Universidad de Vigo, bajo el contrato E-36-2023-0072917 1- RESUMEN: Los h\u00f3rreos son construcciones elevadas para conservar el grano caracter\u00edsticas del Norte de Espa\u00f1a. Actualmente, su inter\u00e9s trasciende su objetivo original y est\u00e1n considerados bienes de inter\u00e9s cultural en Galicia. Esto ha supuesto su protecci\u00f3n e inclusi\u00f3n en cat\u00e1logos oficiales, lo que permite recabar informaci\u00f3n para su estudio. Por desgracia, los cat\u00e1logos est\u00e1n dispersos en diferentes entidades, y presentan formatos que dificultan un tratamiento automatizado y robusto de los datos. Este trabajo extiende estudios etnoastron\u00f3micos previos de dos parroquias del Concello de Vilaboa. Se presentan muestras consistentes, obtenidas in situ y enfocadas a la decoraci\u00f3n astron\u00f3mica, en las parroquias de Vilaboa y Beade, adem\u00e1s de una muestra limpia y homog\u00e9nea de m\u00e1s de 200 h\u00f3rreos en la parroquia de Beade procedente del cat\u00e1logo del Concello de Vigo. En ambas poblaciones, podemos encontrar h\u00f3rreos que presentan decoraci\u00f3n astron\u00f3mica tanto en adornos sobre el tejado (relojes de sol) como tallados en las paredes de piedra (lunas y estrellas). Por ello, adem\u00e1s de caracterizar los datos, se comparan ambas poblaciones desde la perspectiva de la astronom\u00eda cultural. 3- METODOLOGIA: 2- OBJETIVOS: \u2756Actualizar el registro de los h\u00f3rreos en dos ubicaciones diferentes (ayuntamiento Vilaboa y parroquia Beade, Vigo). \u2756Comparar caracteres cuantitativos y cualitativos entre ambas poblaciones con un enfoque etnoastron\u00f3mico. \u2756Buscar si existe alguna relaci\u00f3n entre alguno de los caracteres (principalmente el azimut) y la presencia de decoraci\u00f3n con motivos astron\u00f3micos. Figura 2 - H\u00f3rreos del ayuntamiento de Vilaboa: a- H\u00f3rreo de piedra con una estrella de cinco puntas tallada. b- Decoraci\u00f3n tallada en piedra de dos rosas hexap\u00e9talas. c- Estrella decorativa de cuatro puntas. d- H\u00f3rreo de piedra con 3 estrellas de cuatro puntas talladas y un \u201crespiradero\u201d en forma de media luna. Figura 4 - Histogramas de azimut, medidos entre 0 y 180 grados: a- Ayuntamiento de Vilaboa b- Parroquia de Beade Figura 6 - Diagramas sectoriales para los caracteres cualitativos estudiados: a- Parroquia de Beade. b- Ayuntamiento de Vilaboa. 4- CONCLUSIONES: \u2756Este estudio ha permitido crear una base de datos de los h\u00f3rreos en las poblaciones estudiadas y el registro de sus ubicaciones en mapas. \u2756La prueba de Kolmogorov-Smirnov (a un 5% de significaci\u00f3n) no rechaza la hip\u00f3tesis nula de que ambas muestras provengan de la misma distribuci\u00f3n de azimuts o anchos, pero s\u00ed en longitudes. \u2756La peque\u00f1a concentraci\u00f3n en longitudes bajas en la muestra de Beade no est\u00e1 presente en la de Vilaboa, donde ambas dimensiones muestran distribuciones m\u00e1s uniformes. \u2756La mayor\u00eda (~3/4) de los h\u00f3rreos en Beade est\u00e1n compuestos de materiales mixtos, mientras que la mayor\u00eda (>50%) de los h\u00f3rreos en Vilaboa est\u00e1n hechos de piedra. \u2756La mayor\u00eda de las muestras en Vilaboa muestran decoraciones en las paredes, en comparaci\u00f3n con ~15% en Beade. En ambos casos, la mayor\u00eda tiene motivos astron\u00f3micos. Si incluimos relojes de sol, casi un tercio de los h\u00f3rreos de Beade tienen un elemento astron\u00f3mico. \u2756El uso actual de los h\u00f3rreos puede haberse visto alterado desde la fecha de recogida ", "label": "poster"}
{"text": "Introduction Discussion Selected references Rayner (1998). Psych Bull, 124(3), 372\u2013422. Vitu (2011). In : The Oxford handbook of eye movements (pp. 731\u2013749). Rayner (1979). Perception, 8(1), 21\u201330. McConkie et al. (1989). Percept Psychophys, 46(3), 245\u2013 253. Vitu et al. (2001). Vis Res, 41(25-26), 3513\u20133531. Henderson (1993). Can J Exp Psychol, 47(1), 79-98. van der Linden et al. (2015). J Vis, 15(5), 1\u201318. van der Linden et al. (2015). Att Percept Psychophys, 1\u2013 16. Nazir et al., (1991). Bull Psychon Soc, 29(2), 171\u2013174. Nuthmann et al. (2007). Vis Res, 47(7), 990\u20131002. Vitu et al. (1995). Percept Psychophys, 57(3), 352\u2013364. Adeli et al., (2015), VSS. [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] Away from center Away from center Away from center Away from center 3\u00b0 5\u00b0 PVL e\ufb00ects Away from center Away from center versus PVL OVP I-OVP PVL OVP I-OVP Real objects Meaningless non-objects Methods + 3\u00b0 + + + + Stimulus type (between blocks) Eccentricity (within blocks) 3\u00b0 5\u00b0 5\u00b0 Manipulations Real objects Stimuli Non-objects Hemera objects Width 0.85-2.10\u00b0 Normalized on px Texture synthesis Width constant 0.85\u00b0 Normalized on px + Task Saccade towards the object as fast as possible Landing positions Normalized x coordinates -0.5 0 0.5 on-object o\ufb00-object o\ufb00-object -1 1 Laboratoire de Psychologie Cognitive Lotje van der Linden1, Gregory J. Zelinsky2 and Fran\u00e7oise Vitu1 Aix Marseille universit\u00e9 cnrs l.vanderlinden@cogsci.nl www.cogsci.nl/lvanderlinden 1. Aix Marseille Universit\u00e9, CNRS, Laboratoire de Psychologie Cognitive UMR 7290, Marseille, France 2. Department of Psychology, Stony Brook University, New York, United States Viewing-position e\ufb00ects in meaningless object viewing PVL OVP v\u00eatements v\u00eatements v\u00eatements I-OVP Frequency Re\ufb01xation probability Initial-\ufb01xation duration Eye movements during object viewing \u2192 same regularities [6-8] The center of a stimulus is optimal for visual extraction [9] 20\u00b0 10\u00b0 0\u00b0 10\u00b0 20\u00b0 40\u00b0 60\u00b0 0.0 0.2 0.4 0.6 0.8 1.0 Fovea Relative visual acuity v\u00eatements Degrees from fovea Eye movements during reading \u2192 regularities [1, 2] Eyes land near the center of words \u2192 preferred viewing location (PVL) e\ufb00ect [3] Central landing positions result in less re\ufb01xations \u2192 optimal viewing position (OVP) e\ufb00ect [4] and longer initial \ufb01xation durations \u2192 inverted OVP (I-OVP) e\ufb00ect[5] We know that... Several nocturnal animals were observed. Normal condition Zzzzzzz zzzzzzzzz zzzzzzz zzzz zzzzzzzz. Z-reading condition versus Di\ufb00erences \u2192 cognitive processing Similarities \u2192 visuomotor processing Real objects Meaningless non-objects versus Are PVL, OVP and I-OVP e\ufb00ects Directly caused by these visual-processing advantages? e.g. PVL = strategy to aim at center to optimize visual-information uptake All e\ufb00ects generalize to mindless reading e.g. 10, 11] Is the same true for mindless object viewing? Or are they visuomotor processes? e.g. PVL = automatic center-of-gravity e\ufb00ect Research question: Regularities during reading re\ufb02ect visuomotor constraints PVL, OVP and I-OVP generalized \u2192 The eyes prefer to land at, and stay at, the center of stimuli We found that... regardless of stimulus content This suggests that... PVL, OVP and I-OVP e\ufb00ects re\ufb02ect low-level visuomotor processing and not higher-level ongoing processing such as object recognition This is important for... models on eye guidance in scenes increased predictive power whenimplementing visuomotor constraints [12] Results", "label": "poster"}
{"text": "GND in a Nutshell Ein Normdatensatz beschreibt regel- basiert eine bestimmte Entit\u00e4t. Die Datens\u00e4tze enthalten Informationen, die die entsprechende Entit\u00e4ten ex- plizit charakterisieren und so identifizieren. Die Gemeinsame Normdatei (GND) ist ein Dienst, um Normdaten kooperativ nutzen und verwalten zu k\u00f6nnen. Diese Normdaten repr\u00e4- sentieren und beschreiben Entit\u00e4ten, wie Personen, K\u00f6rperschaften, Kon- ferenzen, Geografika, Sachbegriffe und Werke, die in Bezug zu Kulturgut sowie kulturellen und wissenschaft- lichen Sammlungen stehen. Anforderungen sammeln Auf der Grundlage vorliegender Erfahrungen aus der Text+ Community, die zum Beispiel \u00fcber die zahlreich eingereichten User Stories gesammelt wurden, werden Bedarfe an eine GND- Agentur ermittelt. Diese Aufgabe f\u00fchren wir im Rahmen verschiedener Formate wie dem GND-Forum weiter, wobei ein Ergebnisbericht zum Dezember 2023 vorliegen wird. In Case Studies \u00fcberf\u00fchren Die ermittelten Bedarfe werden in Case Studies \u00fcberf\u00fchrt. In der Datendom\u00e4ne Editions schauen wir anhand von drei Editions- projekten an der SUB G\u00f6ttingen, wie die Bedarfe an GND-Norm- datens\u00e4tzen in konkreten Work- flows umgesetzt werden k\u00f6nnen. \u00c4hnlich werden wir f\u00fcr die Datendom\u00e4nen Collections und Lexical Resources verfahren. Die Workflows aus den Case Studies sollen in allgemeine, skalierbare Workflows bis April 2024 \u00fcbertragen werden. Prototypische Strukturen testen Wir m\u00f6chten die bereits vorhandenen und in Planung befindlichen Strukturen testen. Damit wollen wir gew\u00e4hrleisten, dass die technischen, administrativen und daten- theoretischen Strukturen der Agentur f\u00fcr die Text+ Community ad\u00e4quat sind. Die Produktivnahme ist zum Juni 2025 geplant. Das NFDI-Konsortium Text+ wird gef\u00f6rdert durch die Deutsche Forschungsgemeinschaft (DFG) unter der Projektnummer 460033370. Text+ ist Teil der Hintergrund: \u201eFrankfurt am Main\u201c im GND-Explorer. DNB 2022. CC BY-SA 3.0 Icon Nutshell: Tatyana. Noun Project. Icon Road: Sergey Krivoy. Noun Project. beide CC BY 3.0 https://gnd.network/Webs/gnd/DE/UeberGND/FAQ/faq_node.html Agenturaufgabenbaum. J\u00fcrgen Kett, DNB, Mai 2022. CC BY-SA 3.0 Task Area Infrastructure/Operations Ein Baum in der Roadmap Kontakt: gnd-info@dnb.de Poster: \u201eEin Baum in der GND \u2013 Gemeinsame Normdatei\u201c Inhalt: Text+ Infrastructure/Operations Verantwortlich: Marie Annisius , Barbara Fischer , Alexander Steckel Event: Text+ Plenary, 12-13. September 2022, Mannheim", "label": "poster"}
{"text": "An Exploration of