Daily Papers

Pretrained Foundation Models (PFMs) are regarded as the foundation for various downstream tasks with different data modalities. A PFM (e.g., BERT, ChatGPT, and GPT-4) is trained on large-scale data which provides a reasonable parameter initialization for a wide range of downstream applications. BERT learns bidirectional encoder representations from Transformers, which are trained on large datasets as contextual language models. Similarly, the generative pretrained transformer (GPT) method employs Transformers as the feature extractor and is trained using an autoregressive paradigm on large datasets. Recently, ChatGPT shows promising success on large language models, which applies an autoregressive language model with zero shot or few shot prompting. The remarkable achievements of PFM have brought significant breakthroughs to various fields of AI. Numerous studies have proposed different methods, raising the demand for an updated survey. This study provides a comprehensive review of recent research advancements, challenges, and opportunities for PFMs in text, image, graph, as well as other data modalities. The review covers the basic components and existing pretraining methods used in natural language processing, computer vision, and graph learning. Additionally, it explores advanced PFMs used for different data modalities and unified PFMs that consider data quality and quantity. The review also discusses research related to the fundamentals of PFMs, such as model efficiency and compression, security, and privacy. Finally, the study provides key implications, future research directions, challenges, and open problems in the field of PFMs. Overall, this survey aims to shed light on the research of the PFMs on scalability, security, logical reasoning ability, cross-domain learning ability, and the user-friendly interactive ability for artificial general intelligence.

We present Game-TARS, a generalist game agent trained with a unified, scalable action space anchored to human-aligned native keyboard-mouse inputs. Unlike API- or GUI-based approaches, this paradigm enables large-scale continual pre-training across heterogeneous domains, including OS, web, and simulation games. Game-TARS is pre-trained on over 500B tokens with diverse trajectories and multimodal data. Key techniques include a decaying continual loss to reduce causal confusion and an efficient Sparse-Thinking strategy that balances reasoning depth and inference cost. Experiments show that Game-TARS achieves about 2 times the success rate over the previous sota model on open-world Minecraft tasks, is close to the generality of fresh humans in unseen web 3d games, and outperforms GPT-5, Gemini-2.5-Pro, and Claude-4-Sonnet in FPS benchmarks. Scaling results on training-time and test-time confirm that the unified action space sustains improvements when scaled to cross-game and multimodal data. Our results demonstrate that simple, scalable action representations combined with large-scale pre-training provide a promising path toward generalist agents with broad computer-use abilities.

Financial risk prediction plays a crucial role in the financial sector. Machine learning methods have been widely applied for automatically detecting potential risks and thus saving the cost of labor. However, the development in this field is lagging behind in recent years by the following two facts: 1) the algorithms used are somewhat outdated, especially in the context of the fast advance of generative AI and large language models (LLMs); 2) the lack of a unified and open-sourced financial benchmark has impeded the related research for years. To tackle these issues, we propose FinPT and FinBench: the former is a novel approach for financial risk prediction that conduct Profile Tuning on large pretrained foundation models, and the latter is a set of high-quality datasets on financial risks such as default, fraud, and churn. In FinPT, we fill the financial tabular data into the pre-defined instruction template, obtain natural-language customer profiles by prompting LLMs, and fine-tune large foundation models with the profile text to make predictions. We demonstrate the effectiveness of the proposed FinPT by experimenting with a range of representative strong baselines on FinBench. The analytical studies further deepen the understanding of LLMs for financial risk prediction.

We survey applications of pretrained foundation models in robotics. Traditional deep learning models in robotics are trained on small datasets tailored for specific tasks, which limits their adaptability across diverse applications. In contrast, foundation models pretrained on internet-scale data appear to have superior generalization capabilities, and in some instances display an emergent ability to find zero-shot solutions to problems that are not present in the training data. Foundation models may hold the potential to enhance various components of the robot autonomy stack, from perception to decision-making and control. For example, large language models can generate code or provide common sense reasoning, while vision-language models enable open-vocabulary visual recognition. However, significant open research challenges remain, particularly around the scarcity of robot-relevant training data, safety guarantees and uncertainty quantification, and real-time execution. In this survey, we study recent papers that have used or built foundation models to solve robotics problems. We explore how foundation models contribute to improving robot capabilities in the domains of perception, decision-making, and control. We discuss the challenges hindering the adoption of foundation models in robot autonomy and provide opportunities and potential pathways for future advancements. The GitHub project corresponding to this paper (Preliminary release. We are committed to further enhancing and updating this work to ensure its quality and relevance) can be found here: https://github.com/robotics-survey/Awesome-Robotics-Foundation-Models

Exploring large-scale pretrained foundation models is of significant interest in computer vision because these models can be quickly transferred to many downstream tasks. This paper presents Contrastive Captioner (CoCa), a minimalist design to pretrain an image-text encoder-decoder foundation model jointly with contrastive loss and captioning loss, thereby subsuming model capabilities from contrastive approaches like CLIP and generative methods like SimVLM. In contrast to standard encoder-decoder transformers where all decoder layers attend to encoder outputs, CoCa omits cross-attention in the first half of decoder layers to encode unimodal text representations, and cascades the remaining decoder layers which cross-attend to the image encoder for multimodal image-text representations. We apply a contrastive loss between unimodal image and text embeddings, in addition to a captioning loss on the multimodal decoder outputs which predicts text tokens autoregressively. By sharing the same computational graph, the two training objectives are computed efficiently with minimal overhead. CoCa is pretrained end-to-end and from scratch on both web-scale alt-text data and annotated images by treating all labels simply as text, seamlessly unifying natural language supervision for representation learning. Empirically, CoCa achieves state-of-the-art performance with zero-shot transfer or minimal task-specific adaptation on a broad range of downstream tasks, spanning visual recognition (ImageNet, Kinetics-400/600/700, Moments-in-Time), crossmodal retrieval (MSCOCO, Flickr30K, MSR-VTT), multimodal understanding (VQA, SNLI-VE, NLVR2), and image captioning (MSCOCO, NoCaps). Notably on ImageNet classification, CoCa obtains 86.3% zero-shot top-1 accuracy, 90.6% with a frozen encoder and learned classification head, and new state-of-the-art 91.0% top-1 accuracy on ImageNet with a finetuned encoder.

Recent studies have explored pretrained (foundation) models for vision-based robotic navigation, aiming to achieve generalizable navigation and positive transfer across diverse environments while enhancing zero-shot performance in unseen settings. In this work, we introduce PIG-Nav (Pretrained Image-Goal Navigation), a new approach that further investigates pretraining strategies for vision-based navigation models and contributes in two key areas. Model-wise, we identify two critical design choices that consistently improve the performance of pretrained navigation models: (1) integrating an early-fusion network structure to combine visual observations and goal images via appropriately pretrained Vision Transformer (ViT) image encoder, and (2) introducing suitable auxiliary tasks to enhance global navigation representation learning, thus further improving navigation performance. Dataset-wise, we propose a novel data preprocessing pipeline for efficiently labeling large-scale game video datasets for navigation model training. We demonstrate that augmenting existing open navigation datasets with diverse gameplay videos improves model performance. Our model achieves an average improvement of 22.6% in zero-shot settings and a 37.5% improvement in fine-tuning settings over existing visual navigation foundation models in two complex simulated environments and one real-world environment. These results advance the state-of-the-art in pretrained image-goal navigation models. Notably, our model maintains competitive performance while requiring significantly less fine-tuning data, highlighting its potential for real-world deployment with minimal labeled supervision.

We present a joint Speech and Language Model (SLM), a multitask, multilingual, and dual-modal model that takes advantage of pretrained foundational speech and language models. SLM freezes the pretrained foundation models to maximally preserves their capabilities, and only trains a simple adapter with just 1\% (156M) of the foundation models' parameters. This adaptation not only leads SLM to achieve strong performance on conventional tasks such as speech recognition (ASR) and speech translation (AST), but also introduces the novel capability of zero-shot instruction-following for more diverse tasks: given a speech input and a text instruction, SLM is able to perform unseen generation tasks including contextual biasing ASR using real-time context, dialog generation, speech continuation, and question answering, etc. Our approach demonstrates that the representational gap between pretrained speech and language models might be narrower than one would expect, and can be bridged by a simple adaptation mechanism. As a result, SLM is not only efficient to train, but also inherits strong capabilities already acquired in foundation models of different modalities.

Cell instance segmentation is a fundamental task in digital pathology with broad clinical applications. Recently, vision foundation models, which are predominantly based on Vision Transformers (ViTs), have achieved remarkable success in pathology image analysis. However, their improvements in cell instance segmentation remain limited. A key challenge arises from the tokenization process in ViTs, which substantially reduces the spatial resolution of input images, leading to suboptimal segmentation quality, especially for small and densely packed cells. To address this problem, we propose CellVTA (Cell Vision Transformer with Adapter), a novel method that improves the performance of vision foundation models for cell instance segmentation by incorporating a CNN-based adapter module. This adapter extracts high-resolution spatial information from input images and injects it into the ViT through a cross-attention mechanism. Our method preserves the core architecture of ViT, ensuring seamless integration with pretrained foundation models. Extensive experiments show that CellVTA achieves 0.538 mPQ on the CoNIC dataset and 0.506 mPQ on the PanNuke dataset, which significantly outperforms the state-of-the-art cell segmentation methods. Ablation studies confirm the superiority of our approach over other fine-tuning strategies, including decoder-only fine-tuning and full fine-tuning. Our code and models are publicly available at https://github.com/JieZheng-ShanghaiTech/CellVTA.

We propose a conceptually simple and lightweight framework for improving the robustness of vision models through the combination of knowledge distillation and data augmentation. We address the conjecture that larger models do not make for better teachers by showing strong gains in out-of-distribution robustness when distilling from pretrained foundation models. Following this finding, we propose Discrete Adversarial Distillation (DAD), which leverages a robust teacher to generate adversarial examples and a VQGAN to discretize them, creating more informative samples than standard data augmentation techniques. We provide a theoretical framework for the use of a robust teacher in the knowledge distillation with data augmentation setting and demonstrate strong gains in out-of-distribution robustness and clean accuracy across different student architectures. Notably, our method adds minor computational overhead compared to similar techniques and can be easily combined with other data augmentations for further improvements.

Foundation models pretrained on extensive datasets, such as GroundingDINO and LAE-DINO, have performed remarkably in the cross-domain few-shot object detection (CD-FSOD) task. Through rigorous few-shot training, we found that the integration of image-based data augmentation techniques and grid-based sub-domain search strategy significantly enhances the performance of these foundation models. Building upon GroundingDINO, we employed several widely used image augmentation methods and established optimization objectives to effectively navigate the expansive domain space in search of optimal sub-domains. This approach facilitates efficient few-shot object detection and introduces an approach to solving the CD-FSOD problem by efficiently searching for the optimal parameter configuration from the foundation model. Our findings substantially advance the practical deployment of vision-language models in data-scarce environments, offering critical insights into optimizing their cross-domain generalization capabilities without labor-intensive retraining. Code is available at https://github.com/jaychempan/ETS.

The temperature parameter plays a profound role during training and/or inference with large foundation models (LFMs) such as large language models (LLMs) and CLIP models. Particularly, it adjusts the logits in the softmax function in LLMs, which is crucial for next token generation, and it scales the similarities in the contrastive loss for training CLIP models. A significant question remains: Is it viable to learn a neural network to predict a personalized temperature of any input data for enhancing LFMs"? In this paper, we present a principled framework for learning a small yet generalizable temperature prediction network (TempNet) to improve LFMs. Our solution is composed of a novel learning framework with a robust loss underpinned by constrained distributionally robust optimization (DRO), and a properly designed TempNet with theoretical inspiration. TempNet can be trained together with a large foundation model from scratch or learned separately given a pretrained foundation model. It is not only useful for predicting personalized temperature to promote the training of LFMs but also generalizable and transferable to new tasks. Our experiments on LLMs and CLIP models demonstrate that TempNet greatly improves the performance of existing solutions or models, e.g. Table 1. The code to reproduce the experimental results in this paper can be found at https://github.com/zhqiu/TempNet.

Pretrained foundation models offer substantial benefits for a wide range of downstream tasks, which can be one of the most potential techniques to access artificial general intelligence. However, scaling up foundation transformers for maximal task-agnostic knowledge has brought about computational challenges, especially on resource-limited devices such as mobiles. This work proposes the first Binary Pretrained Foundation Transformer (BiPFT) for natural language understanding (NLU) tasks, which remarkably saves 56 times operations and 28 times memory. In contrast to previous task-specific binary transformers, BiPFT exhibits a substantial enhancement in the learning capabilities of binary neural networks (BNNs), promoting BNNs into the era of pre-training. Benefiting from extensive pretraining data, we further propose a data-driven binarization method. Specifically, we first analyze the binarization error in self-attention operations and derive the polynomials of binarization error. To simulate full-precision self-attention, we define binarization error as binarization residual polynomials, and then introduce low-rank estimators to model these polynomials. Extensive experiments validate the effectiveness of BiPFTs, surpassing task-specific baseline by 15.4% average performance on the GLUE benchmark. BiPFT also demonstrates improved robustness to hyperparameter changes, improved optimization efficiency, and reduced reliance on downstream distillation, which consequently generalize on various NLU tasks and simplify the downstream pipeline of BNNs. Our code and pretrained models are publicly available at https://github.com/Xingrun-Xing/BiPFT.

Generative artificial intelligence (AI) systems based on large-scale pretrained foundation models (PFMs) such as vision-language models, large language models (LLMs), diffusion models and vision-language-action (VLA) models have demonstrated the ability to solve complex and truly non-trivial AI problems in a wide variety of domains and contexts. Multimodal large language models (MLLMs), in particular, learn from vast and diverse data sources, allowing rich and nuanced representations of the world and, thereby, providing extensive capabilities, including the ability to reason, engage in meaningful dialog; collaborate with humans and other agents to jointly solve complex problems; and understand social and emotional aspects of humans. Despite this impressive feat, the cognitive abilities of state-of-the-art LLMs trained on large-scale datasets are still superficial and brittle. Consequently, generic LLMs are severely limited in their generalist capabilities. A number of foundational problems -- embodiment, symbol grounding, causality and memory -- are required to be addressed for LLMs to attain human-level general intelligence. These concepts are more aligned with human cognition and provide LLMs with inherent human-like cognitive properties that support the realization of physically-plausible, semantically meaningful, flexible and more generalizable knowledge and intelligence. In this work, we discuss the aforementioned foundational issues and survey state-of-the art approaches for implementing these concepts in LLMs. Specifically, we discuss how the principles of embodiment, symbol grounding, causality and memory can be leveraged toward the attainment of artificial general intelligence (AGI) in an organic manner.

Broad, open source availability of large pretrained foundation models on the internet through platforms such as HuggingFace has taken the world of practical deep learning by storm. A classical pipeline for neural network training now typically consists of finetuning these pretrained network on a small target dataset instead of training from scratch. In the case of large models this can be done even on modest hardware using a low rank training technique known as Low-Rank Adaptation (LoRA). While Low Rank training has already been studied in the continual learning setting, existing works often consider storing the learned adapter along with the existing model but rarely attempt to modify the weights of the pretrained model by merging the LoRA with the existing weights after finishing the training of each task. In this article we investigate this setting and study the impact of LoRA rank on the forgetting of the pretraining foundation task and on the plasticity and forgetting of subsequent ones. We observe that this rank has an important impact on forgetting of both the pretraining and downstream tasks. We also observe that vision transformers finetuned in that way exhibit a sort of ``contextual'' forgetting, a behaviour that we do not observe for residual networks and that we believe has not been observed yet in previous continual learning works.

Understanding and reasoning about complex 3D environments requires structured scene representations that capture not only objects but also their semantic and spatial relationships. While recent works on 3D scene graph generation have leveraged pretrained VLMs without task-specific fine-tuning, they are largely confined to single-view settings, fail to support incremental updates as new observations arrive and lack explicit geometric grounding in 3D space, all of which are essential for embodied scenarios. In this paper, we propose, ZING-3D, a framework that leverages the vast knowledge of pretrained foundation models to enable open-vocabulary recognition and generate a rich semantic representation of the scene in a zero-shot manner while also enabling incremental updates and geometric grounding in 3D space, making it suitable for downstream robotics applications. Our approach leverages VLM reasoning to generate a rich 2D scene graph, which is grounded in 3D using depth information. Nodes represent open-vocabulary objects with features, 3D locations, and semantic context, while edges capture spatial and semantic relations with inter-object distances. Our experiments on scenes from the Replica and HM3D dataset show that ZING-3D is effective at capturing spatial and relational knowledge without the need of task-specific training.

3D object part segmentation is essential in computer vision applications. While substantial progress has been made in 2D object part segmentation, the 3D counterpart has received less attention, in part due to the scarcity of annotated 3D datasets, which are expensive to collect. In this work, we propose to leverage a few annotated 3D shapes or richly annotated 2D datasets to perform 3D object part segmentation. We present our novel approach, termed 3-By-2 that achieves SOTA performance on different benchmarks with various granularity levels. By using features from pretrained foundation models and exploiting semantic and geometric correspondences, we are able to overcome the challenges of limited 3D annotations. Our approach leverages available 2D labels, enabling effective 3D object part segmentation. Our method 3-By-2 can accommodate various part taxonomies and granularities, demonstrating interesting part label transfer ability across different object categories. Project website: https://ngailapdi.github.io/projects/3by2/.

Large-scale pretrained foundation models have been an emerging paradigm for building artificial intelligence (AI) systems, which can be quickly adapted to a wide range of downstream tasks. This paper presents mPLUG, a new vision-language foundation model for both cross-modal understanding and generation. Most existing pre-trained models suffer from the problems of low computational efficiency and information asymmetry brought by the long visual sequence in cross-modal alignment. To address these problems, mPLUG introduces an effective and efficient vision-language architecture with novel cross-modal skip-connections, which creates inter-layer shortcuts that skip a certain number of layers for time-consuming full self-attention on the vision side. mPLUG is pre-trained end-to-end on large-scale image-text pairs with both discriminative and generative objectives. It achieves state-of-the-art results on a wide range of vision-language downstream tasks, such as image captioning, image-text retrieval, visual grounding and visual question answering. mPLUG also demonstrates strong zero-shot transferability when directly transferred to multiple video-language tasks.

Transformers, particularly Vision Transformers (ViTs), have achieved state-of-the-art performance in large-scale image classification. However, they often require large amounts of data and can exhibit biases that limit their robustness and generalizability. This paper introduces ForAug, a novel data augmentation scheme that addresses these challenges and explicitly includes inductive biases, which commonly are part of the neural network architecture, into the training data. ForAug is constructed by using pretrained foundation models to separate and recombine foreground objects with different backgrounds, enabling fine-grained control over image composition during training. It thus increases the data diversity and effective number of training samples. We demonstrate that training on ForNet, the application of ForAug to ImageNet, significantly improves the accuracy of ViTs and other architectures by up to 4.5 percentage points (p.p.) on ImageNet and 7.3 p.p. on downstream tasks. Importantly, ForAug enables novel ways of analyzing model behavior and quantifying biases. Namely, we introduce metrics for background robustness, foreground focus, center bias, and size bias and show that training on ForNet substantially reduces these biases compared to training on ImageNet. In summary, ForAug provides a valuable tool for analyzing and mitigating biases, enabling the development of more robust and reliable computer vision models. Our code and dataset are publicly available at https://github.com/tobna/ForAug.

This paper identifies OpenSDI, a challenge for spotting diffusion-generated images in open-world settings. In response to this challenge, we define a new benchmark, the OpenSDI dataset (OpenSDID), which stands out from existing datasets due to its diverse use of large vision-language models that simulate open-world diffusion-based manipulations. Another outstanding feature of OpenSDID is its inclusion of both detection and localization tasks for images manipulated globally and locally by diffusion models. To address the OpenSDI challenge, we propose a Synergizing Pretrained Models (SPM) scheme to build up a mixture of foundation models. This approach exploits a collaboration mechanism with multiple pretrained foundation models to enhance generalization in the OpenSDI context, moving beyond traditional training by synergizing multiple pretrained models through prompting and attending strategies. Building on this scheme, we introduce MaskCLIP, an SPM-based model that aligns Contrastive Language-Image Pre-Training (CLIP) with Masked Autoencoder (MAE). Extensive evaluations on OpenSDID show that MaskCLIP significantly outperforms current state-of-the-art methods for the OpenSDI challenge, achieving remarkable relative improvements of 14.23% in IoU (14.11% in F1) and 2.05% in accuracy (2.38% in F1) compared to the second-best model in localization and detection tasks, respectively. Our dataset and code are available at https://github.com/iamwangyabin/OpenSDI.

As instruction-tuned large language models (LLMs) evolve, aligning pretrained foundation models presents increasing challenges. Existing alignment strategies, which typically leverage diverse and high-quality data sources, often overlook the intrinsic uncertainty of tasks, learning all data samples equally. This may lead to suboptimal data efficiency and model performance. In response, we propose uncertainty-aware learning (UAL) to improve the model alignment of different task scenarios, by introducing the sample uncertainty (elicited from more capable LLMs). We implement UAL in a simple fashion -- adaptively setting the label smoothing value of training according to the uncertainty of individual samples. Analysis shows that our UAL indeed facilitates better token clustering in the feature space, validating our hypothesis. Extensive experiments on widely used benchmarks demonstrate that our UAL significantly and consistently outperforms standard supervised fine-tuning. Notably, LLMs aligned in a mixed scenario have achieved an average improvement of 10.62\% on high-entropy tasks (i.e., AlpacaEval leaderboard), and 1.81\% on complex low-entropy tasks (i.e., MetaMath and GSM8K).

Although audio generation has been widely studied over recent years, video-aligned audio generation still remains a relatively unexplored frontier. To address this gap, we introduce StereoSync, a novel and efficient model designed to generate audio that is both temporally synchronized with a reference video and spatially aligned with its visual context. Moreover, StereoSync also achieves efficiency by leveraging pretrained foundation models, reducing the need for extensive training while maintaining high-quality synthesis. Unlike existing methods that primarily focus on temporal synchronization, StereoSync introduces a significant advancement by incorporating spatial awareness into video-aligned audio generation. Indeed, given an input video, our approach extracts spatial cues from depth maps and bounding boxes, using them as cross-attention conditioning in a diffusion-based audio generation model. Such an approach allows StereoSync to go beyond simple synchronization, producing stereo audio that dynamically adapts to the spatial structure and movement of a video scene. We evaluate StereoSync on Walking The Maps, a curated dataset comprising videos from video games that feature animated characters walking through diverse environments. Experimental results demonstrate the ability of StereoSync to achieve both temporal and spatial alignment, advancing the state of the art in video-to-audio generation and resulting in a significantly more immersive and realistic audio experience.

The objective of this paper is an automatic Audio Description (AD) model that ingests movies and outputs AD in text form. Generating high-quality movie AD is challenging due to the dependency of the descriptions on context, and the limited amount of training data available. In this work, we leverage the power of pretrained foundation models, such as GPT and CLIP, and only train a mapping network that bridges the two models for visually-conditioned text generation. In order to obtain high-quality AD, we make the following four contributions: (i) we incorporate context from the movie clip, AD from previous clips, as well as the subtitles; (ii) we address the lack of training data by pretraining on large-scale datasets, where visual or contextual information is unavailable, e.g. text-only AD without movies or visual captioning datasets without context; (iii) we improve on the currently available AD datasets, by removing label noise in the MAD dataset, and adding character naming information; and (iv) we obtain strong results on the movie AD task compared with previous methods.

Humans and animals have a rich and flexible understanding of the physical world, which enables them to infer the underlying dynamical trajectories of objects and events, plausible future states, and use that to plan and anticipate the consequences of actions. However, the neural mechanisms underlying these computations are unclear. We combine a goal-driven modeling approach with dense neurophysiological data and high-throughput human behavioral readouts to directly impinge on this question. Specifically, we construct and evaluate several classes of sensory-cognitive networks to predict the future state of rich, ethologically-relevant environments, ranging from self-supervised end-to-end models with pixel-wise or object-centric objectives, to models that future predict in the latent space of purely static image-based or dynamic video-based pretrained foundation models. We find strong differentiation across these model classes in their ability to predict neural and behavioral data both within and across diverse environments. In particular, we find that neural responses are currently best predicted by models trained to predict the future state of their environment in the latent space of pretrained foundation models optimized for dynamic scenes in a self-supervised manner. Notably, models that future predict in the latent space of video foundation models that are optimized to support a diverse range of sensorimotor tasks, reasonably match both human behavioral error patterns and neural dynamics across all environmental scenarios that we were able to test. Overall, these findings suggest that the neural mechanisms and behaviors of primate mental simulation are thus far most consistent with being optimized to future predict on dynamic, reusable visual representations that are useful for embodied AI more generally.

REPA and its variants effectively mitigate training challenges in diffusion models by incorporating external visual representations from pretrained models, through alignment between the noisy hidden projections of denoising networks and foundational clean image representations. We argue that the external alignment, which is absent during the entire denoising inference process, falls short of fully harnessing the potential of discriminative representations. In this work, we propose a straightforward method called Representation Entanglement for Generation (REG), which entangles low-level image latents with a single high-level class token from pretrained foundation models for denoising. REG acquires the capability to produce coherent image-class pairs directly from pure noise, substantially improving both generation quality and training efficiency. This is accomplished with negligible additional inference overhead, requiring only one single additional token for denoising (<0.5\% increase in FLOPs and latency). The inference process concurrently reconstructs both image latents and their corresponding global semantics, where the acquired semantic knowledge actively guides and enhances the image generation process. On ImageNet 256times256, SiT-XL/2 + REG demonstrates remarkable convergence acceleration, achieving 63times and 23times faster training than SiT-XL/2 and SiT-XL/2 + REPA, respectively. More impressively, SiT-L/2 + REG trained for merely 400K iterations outperforms SiT-XL/2 + REPA trained for 4M iterations (10times longer). Code is available at: https://github.com/Martinser/REG.

Cloud segmentation is a critical challenge in remote sensing image interpretation, as its accuracy directly impacts the effectiveness of subsequent data processing and analysis. Recently, vision foundation models (VFM) have demonstrated powerful generalization capabilities across various visual tasks. In this paper, we present a parameter-efficient adaptive approach, termed Cloud-Adapter, designed to enhance the accuracy and robustness of cloud segmentation. Our method leverages a VFM pretrained on general domain data, which remains frozen, eliminating the need for additional training. Cloud-Adapter incorporates a lightweight spatial perception module that initially utilizes a convolutional neural network (ConvNet) to extract dense spatial representations. These multi-scale features are then aggregated and serve as contextual inputs to an adapting module, which modulates the frozen transformer layers within the VFM. Experimental results demonstrate that the Cloud-Adapter approach, utilizing only 0.6% of the trainable parameters of the frozen backbone, achieves substantial performance gains. Cloud-Adapter consistently attains state-of-the-art (SOTA) performance across a wide variety of cloud segmentation datasets from multiple satellite sources, sensor series, data processing levels, land cover scenarios, and annotation granularities. We have released the source code and pretrained models at https://github.com/XavierJiezou/Cloud-Adapter to support further research.

Building video-language foundation models is costly and difficult due to the redundant nature of video data and the lack of high-quality video-language datasets. In this paper, we propose an efficient framework to harvest video foundation models from image ones. Our method is intuitively simple by randomly dropping input video patches and masking out input text during the post-pretraining procedure. The patch dropping boosts the training efficiency significantly and text masking enforces the learning of cross-modal fusion. We conduct extensive experiments to validate the effectiveness of our method on a wide range of video-language downstream tasks including various zero-shot tasks, video question answering, and video-text retrieval. Despite its simplicity, our method achieves state-of-the-art performances, which are comparable to some heavily pretrained video foundation models. Our method is extremely efficient and can be trained in less than one day on 8 GPUs, requiring only WebVid-10M as pretraining data. We hope our method can serve as a simple yet strong counterpart for prevalent video foundation models, provide useful insights when building them, and make large pretrained models more accessible and sustainable. This is part of the InternVideo project https://github.com/OpenGVLab/InternVideo.

While the general machine learning (ML) community has benefited from public datasets, tasks, and models, the progress of ML in healthcare has been hampered by a lack of such shared assets. The success of foundation models creates new challenges for healthcare ML by requiring access to shared pretrained models to validate performance benefits. We help address these challenges through three contributions. First, we publish a new dataset, EHRSHOT, which contains deidentified structured data from the electronic health records (EHRs) of 6,739 patients from Stanford Medicine. Unlike MIMIC-III/IV and other popular EHR datasets, EHRSHOT is longitudinal and not restricted to ICU/ED patients. Second, we publish the weights of CLMBR-T-base, a 141M parameter clinical foundation model pretrained on the structured EHR data of 2.57M patients. We are one of the first to fully release such a model for coded EHR data; in contrast, most prior models released for clinical data (e.g. GatorTron, ClinicalBERT) only work with unstructured text and cannot process the rich, structured data within an EHR. We provide an end-to-end pipeline for the community to validate and build upon its performance. Third, we define 15 few-shot clinical prediction tasks, enabling evaluation of foundation models on benefits such as sample efficiency and task adaptation. Our model and dataset are available via a research data use agreement from the Stanford AIMI Center. Code to reproduce our results are available at our Github repo: https://github.com/som-shahlab/ehrshot-benchmark

Pretrained vision foundation models (VFMs) advance robotic learning via rich visual representations, yet individual VFMs typically excel only in specific domains, limiting generality across tasks. Distilling multiple VFMs into a unified representation for policy can mitigate this limitation but often yields inflexible task-specific feature selection and requires costly full re-training to incorporate robot-domain knowledge. We propose VER, a Vision Expert transformer for Robot learning. During pretraining, VER distills multiple VFMs into a vision expert library. It then fine-tunes only a lightweight routing network (fewer than 0.4% of parameters) to dynamically select task-relevant experts from the pretrained library for downstream robot tasks. We further introduce Patchwise Expert Routing with Curriculum Top-K Annealing to improve both flexibility and precision of dynamic expert selection. Moreover, VER supports parameter-efficient finetuning for scalable expert utilization and adaptive robot-domain knowledge integration. Across 17 diverse robotic tasks and multiple policy heads, VER achieves state-of-the-art performance. We find that VER reduces large-norm outliers in task-irrelevant regions (e.g., background) and concentrates on task-critical regions. Visualizations and codes can be found in https://yixiaowang7.github.io/ver_page/.

There has been significant progress in open-source text-only translation large language models (LLMs) with better language coverage and quality. However, these models can be only used in cascaded pipelines for speech translation (ST), performing automatic speech recognition first followed by translation. This introduces additional latency, which is particularly critical in simultaneous ST (SimulST), and prevents the model from exploiting multimodal context, such as images, which can aid disambiguation. Pretrained multimodal foundation models (MMFMs) already possess strong perception and reasoning capabilities across multiple modalities, but generally lack the multilingual coverage and specialized translation performance of dedicated translation LLMs. To build an effective multimodal translation system, we propose an end-to-end approach that fuses MMFMs with translation LLMs. We introduce a novel fusion strategy that connects hidden states from multiple layers of a pretrained MMFM to a translation LLM, enabling joint end-to-end training. The resulting model, OmniFusion, built on Omni 2.5-7B as the MMFM and SeedX PPO-7B as the translation LLM, can perform speech-to-text, speech-and-image-to-text, and text-and-image-to-text translation. Experiments demonstrate that OmniFusion effectively leverages both audio and visual inputs, achieves a 1-second latency reduction in SimulST compared to cascaded pipelines and also improves the overall translation qualityCode is available at https://github.com/saikoneru/OmniFusion.

People say, "A picture is worth a thousand words". Then how can we get the rich information out of the image? We argue that by using visual clues to bridge large pretrained vision foundation models and language models, we can do so without any extra cross-modal training. Thanks to the strong zero-shot capability of foundation models, we start by constructing a rich semantic representation of the image (e.g., image tags, object attributes / locations, captions) as a structured textual prompt, called visual clues, using a vision foundation model. Based on visual clues, we use large language model to produce a series of comprehensive descriptions for the visual content, which is then verified by the vision model again to select the candidate that aligns best with the image. We evaluate the quality of generated descriptions by quantitative and qualitative measurement. The results demonstrate the effectiveness of such a structured semantic representation.

Recent advances in scene understanding have leveraged multimodal large language models (MLLMs) for 3D reasoning by capitalizing on their strong 2D pretraining. However, the lack of explicit 3D data during MLLM pretraining limits 3D representation capability. In this paper, we investigate the 3D-awareness of MLLMs by evaluating multi-view correspondence and reveal a strong positive correlation between the quality of 3D-aware representation and downstream task performance. Motivated by this, we propose 3DRS, a framework that enhances MLLM 3D representation learning by introducing supervision from pretrained 3D foundation models. Our approach aligns MLLM visual features with rich 3D knowledge distilled from 3D models, effectively improving scene understanding. Extensive experiments across multiple benchmarks and MLLMs -- including visual grounding, captioning, and question answering -- demonstrate consistent performance gains. Project page: https://visual-ai.github.io/3drs

Vision-language-action (VLA) models have recently shown strong potential in enabling robots to follow language instructions and execute precise actions. However, most VLAs are built upon vision-language models pretrained solely on 2D data, which lack accurate spatial awareness and hinder their ability to operate in the 3D physical world. Existing solutions attempt to incorporate explicit 3D sensor inputs such as depth maps or point clouds, but these approaches face challenges due to sensor noise, hardware heterogeneity, and incomplete depth coverage in existing datasets. Alternative methods that estimate 3D cues from 2D images also suffer from the limited performance of depth estimators.We propose Spatial Forcing (SF), a simple yet effective alignment strategy that implicitly forces VLA models to develop spatial comprehension capabilities without relying on explicit 3D inputs or depth estimators. SF aligns intermediate visual embeddings of VLAs with geometric representations produced by pretrained 3D foundation models. By enforcing alignment at intermediate layers, SF guides VLAs to encode richer spatial representations that enhance action precision.Extensive experiments in simulation and real-world environments demonstrate that SF achieves state-of-the-art results, surpassing both 2D- and 3D-based VLAs. SF further accelerates training by up to 3.8x and improves data efficiency across diverse robotic tasks. Project page is at https://spatial-forcing.github.io/

Predicting future dynamics is crucial for applications like autonomous driving and robotics, where understanding the environment is key. Existing pixel-level methods are computationally expensive and often focus on irrelevant details. To address these challenges, we introduce DINO-Foresight, a novel framework that operates in the semantic feature space of pretrained Vision Foundation Models (VFMs). Our approach trains a masked feature transformer in a self-supervised manner to predict the evolution of VFM features over time. By forecasting these features, we can apply off-the-shelf, task-specific heads for various scene understanding tasks. In this framework, VFM features are treated as a latent space, to which different heads attach to perform specific tasks for future-frame analysis. Extensive experiments show that our framework outperforms existing methods, demonstrating its robustness and scalability. Additionally, we highlight how intermediate transformer representations in DINO-Foresight improve downstream task performance, offering a promising path for the self-supervised enhancement of VFM features. We provide the implementation code at https://github.com/Sta8is/DINO-Foresight .

Instance segmentation demands costly per-pixel annotations and large models. We introduce CAST, a semi-supervised knowledge distillation (SSKD) framework that compresses pretrained vision foundation models (VFM) into compact experts using limited labeled and abundant unlabeled data. CAST unfolds in three stages: (1) domain adaptation of the VFM teacher(s) via self-training with contrastive pixel calibration, (2) distillation into a compact student via a unified multi-objective loss that couples standard supervision and pseudo-labels with our instance-aware pixel-wise contrastive term, and (3) fine-tuning on labeled data to remove residual pseudo-label bias. Central to CAST is an instance-aware pixel-wise contrastive loss that fuses mask and class scores to mine informative negatives and enforce clear inter-instance margins. By maintaining this contrastive signal across both adaptation and distillation, we align teacher and student embeddings and fully leverage unlabeled images. On Cityscapes and ADE20K, our ~11X smaller student surpasses its adapted VFM teacher(s) by +3.4 AP (33.9 vs. 30.5) and +1.5 AP (16.7 vs. 15.2) and outperforms state-of-the-art semi-supervised approaches.

Training native 3D texture generative models remains a fundamental yet challenging problem, largely due to the limited availability of large-scale, high-quality 3D texture datasets. This scarcity hinders generalization to real-world scenarios. To address this, most existing methods finetune foundation image generative models to exploit their learned visual priors. However, these approaches typically generate only multi-view images and rely on post-processing to produce UV texture maps -- an essential representation in modern graphics pipelines. Such two-stage pipelines often suffer from error accumulation and spatial inconsistencies across the 3D surface. In this paper, we introduce SeqTex, a novel end-to-end framework that leverages the visual knowledge encoded in pretrained video foundation models to directly generate complete UV texture maps. Unlike previous methods that model the distribution of UV textures in isolation, SeqTex reformulates the task as a sequence generation problem, enabling the model to learn the joint distribution of multi-view renderings and UV textures. This design effectively transfers the consistent image-space priors from video foundation models into the UV domain. To further enhance performance, we propose several architectural innovations: a decoupled multi-view and UV branch design, geometry-informed attention to guide cross-domain feature alignment, and adaptive token resolution to preserve fine texture details while maintaining computational efficiency. Together, these components allow SeqTex to fully utilize pretrained video priors and synthesize high-fidelity UV texture maps without the need for post-processing. Extensive experiments show that SeqTex achieves state-of-the-art performance on both image-conditioned and text-conditioned 3D texture generation tasks, with superior 3D consistency, texture-geometry alignment, and real-world generalization.

Multimodal models have demonstrated powerful capabilities in complex tasks requiring multimodal alignment including zero-shot classification and cross-modal retrieval. However, existing models typically rely on millions of paired multimodal samples, which are prohibitively expensive or infeasible to obtain in many domains. In this work, we explore the feasibility of building multimodal models with limited amount of paired data by aligning pretrained unimodal foundation models. We show that high-quality alignment is possible with as few as tens of thousands of paired samplesx2013less than 1% of the data typically used in the field. To achieve this, we introduce STRUCTURE, an effective regularization technique that preserves the neighborhood geometry of the latent space of unimodal encoders. Additionally, we show that aligning last layers is often suboptimal and demonstrate the benefits of aligning the layers with the highest representational similarity across modalities. These two components can be readily incorporated into existing alignment methods, yielding substantial gains across 24 zero-shot image classification and retrieval benchmarks, with average relative improvement of 51.6% in classification and 91.8% in retrieval tasks. Our results highlight the effectiveness and broad applicability of our framework for limited-sample multimodal learning and offer a promising path forward for resource-constrained domains.

For equitable deployment of AI tools in hospitals and healthcare facilities, we need Deep Segmentation Networks that offer high performance and can be trained on cost-effective GPUs with limited memory and large batch sizes. In this work, we propose Wave-GMS, a lightweight and efficient multi-scale generative model for medical image segmentation. Wave-GMS has a substantially smaller number of trainable parameters, does not require loading memory-intensive pretrained vision foundation models, and supports training with large batch sizes on GPUs with limited memory. We conducted extensive experiments on four publicly available datasets (BUS, BUSI, Kvasir-Instrument, and HAM10000), demonstrating that Wave-GMS achieves state-of-the-art segmentation performance with superior cross-domain generalizability, while requiring only ~2.6M trainable parameters. Code is available at https://github.com/ATPLab-LUMS/Wave-GMS.

In the context of imitation learning, visuomotor-based diffusion policy learning is one of the main directions in robotic manipulation. Most of these approaches rely on point clouds as observation inputs and construct scene representations through point clouds feature learning, which enables them to achieve remarkable accuracy. However, the existing literature lacks an in-depth exploration of vision-only solutions that have significant potential. In this paper, we propose a Vision-Only and single-view Diffusion Policy learning method (VO-DP) that leverages pretrained visual foundation models to achieve effective fusion of semantic and geometric features. We utilize intermediate features from VGGT incorporating semantic features from DINOv2 and geometric features from Alternating Attention blocks. Features are fused via cross-attention and spatially compressed with a CNN to form the input to the policy head. Extensive experiments demonstrate that VO-DP not only outperforms the vision-only baseline DP significantly but also exhibits distinct performance trends against the point cloud-based method DP3: in simulation tasks, VO-DP achieves an average success rate of 64.6% on par with DP3 64.0% and far higher than DP 34.8%, while in real-world tasks, it reaches 87.9%, outperforming both DP3 67.5% and DP 11.2% by a notable margin. Further robustness evaluations confirm that VO-DP remains highly stable under varying conditions including color, size, background, and lighting. Lastly, we open-source a training library for robotic manipulation. Built on Accelerate, this library supports multi-machine and multi-GPU parallel training, as well as mixed precision training. It is compatible with visuomotor policies such as DP, DP3 and VO-DP, and also supports the RoboTwin simulator.

Anomaly detection in medical images is an important yet challenging task due to the diversity of possible anomalies and the practical impossibility of collecting comprehensively annotated data sets. In this work, we tackle unsupervised medical anomaly detection proposing a modernized autoencoder-based framework, the Q-Former Autoencoder, that leverages state-of-the-art pretrained vision foundation models, such as DINO, DINOv2 and Masked Autoencoder. Instead of training encoders from scratch, we directly utilize frozen vision foundation models as feature extractors, enabling rich, multi-stage, high-level representations without domain-specific fine-tuning. We propose the usage of the Q-Former architecture as the bottleneck, which enables the control of the length of the reconstruction sequence, while efficiently aggregating multiscale features. Additionally, we incorporate a perceptual loss computed using features from a pretrained Masked Autoencoder, guiding the reconstruction towards semantically meaningful structures. Our framework is evaluated on four diverse medical anomaly detection benchmarks, achieving state-of-the-art results on BraTS2021, RESC, and RSNA. Our results highlight the potential of vision foundation model encoders, pretrained on natural images, to generalize effectively to medical image analysis tasks without further fine-tuning. We release the code and models at https://github.com/emirhanbayar/QFAE.

Pretraining with large-scale 3D volumes has a potential for improving the segmentation performance on a target medical image dataset where the training images and annotations are limited. Due to the high cost of acquiring pixel-level segmentation annotations on the large-scale pretraining dataset, pretraining with unannotated images is highly desirable. In this work, we propose a novel self-supervised learning strategy named Volume Fusion (VF) for pretraining 3D segmentation models. It fuses several random patches from a foreground sub-volume to a background sub-volume based on a predefined set of discrete fusion coefficients, and forces the model to predict the fusion coefficient of each voxel, which is formulated as a self-supervised segmentation task without manual annotations. Additionally, we propose a novel network architecture based on parallel convolution and transformer blocks that is suitable to be transferred to different downstream segmentation tasks with various scales of organs and lesions. The proposed model was pretrained with 110k unannotated 3D CT volumes, and experiments with different downstream segmentation targets including head and neck organs, thoracic/abdominal organs showed that our pretrained model largely outperformed training from scratch and several state-of-the-art self-supervised training methods and segmentation models. The code and pretrained model are available at https://github.com/openmedlab/MIS-FM.

Foundation models are predominantly trained in an unsupervised or self-supervised manner on highly diverse and large-scale datasets, making them broadly applicable to various downstream tasks. In this work, we investigate for the first time whether such models are suitable for the specific domain of face recognition. We further propose and demonstrate the adaptation of these models for face recognition across different levels of data availability. Extensive experiments are conducted on multiple foundation models and datasets of varying scales for training and fine-tuning, with evaluation on a wide range of benchmarks. Our results indicate that, despite their versatility, pre-trained foundation models underperform in face recognition compared to similar architectures trained specifically for this task. However, fine-tuning foundation models yields promising results, often surpassing models trained from scratch when training data is limited. Even with access to large-scale face recognition training datasets, fine-tuned foundation models perform comparably to models trained from scratch, but with lower training computational costs and without relying on the assumption of extensive data availability. Our analysis also explores bias in face recognition, with slightly higher bias observed in some settings when using foundation models.

Foundation models pretrained on diverse data at scale have demonstrated extraordinary capabilities in a wide range of vision and language tasks. When such models are deployed in real world environments, they inevitably interface with other entities and agents. For example, language models are often used to interact with human beings through dialogue, and visual perception models are used to autonomously navigate neighborhood streets. In response to these developments, new paradigms are emerging for training foundation models to interact with other agents and perform long-term reasoning. These paradigms leverage the existence of ever-larger datasets curated for multimodal, multitask, and generalist interaction. Research at the intersection of foundation models and decision making holds tremendous promise for creating powerful new systems that can interact effectively across a diverse range of applications such as dialogue, autonomous driving, healthcare, education, and robotics. In this manuscript, we examine the scope of foundation models for decision making, and provide conceptual tools and technical background for understanding the problem space and exploring new research directions. We review recent approaches that ground foundation models in practical decision making applications through a variety of methods such as prompting, conditional generative modeling, planning, optimal control, and reinforcement learning, and discuss common challenges and open problems in the field.

A central challenge towards developing robots that can relate human language to their perception and actions is the scarcity of natural language annotations in diverse robot datasets. Moreover, robot policies that follow natural language instructions are typically trained on either templated language or expensive human-labeled instructions, hindering their scalability. To this end, we introduce NILS: Natural language Instruction Labeling for Scalability. NILS automatically labels uncurated, long-horizon robot data at scale in a zero-shot manner without any human intervention. NILS combines pretrained vision-language foundation models in order to detect objects in a scene, detect object-centric changes, segment tasks from large datasets of unlabelled interaction data and ultimately label behavior datasets. Evaluations on BridgeV2, Fractal, and a kitchen play dataset show that NILS can autonomously annotate diverse robot demonstrations of unlabeled and unstructured datasets while alleviating several shortcomings of crowdsourced human annotations, such as low data quality and diversity. We use NILS to label over 115k trajectories obtained from over 430 hours of robot data. We open-source our auto-labeling code and generated annotations on our website: http://robottasklabeling.github.io.

Time series anomaly detection forms a very crucial area in several domains but poses substantial challenges. Due to time series data possessing seasonality, trends, noise, and evolving patterns (concept drift), it becomes very difficult to set a general notion of what constitutes normal behavior. Anomalies themselves could be varied, ranging from a single outlier to contextual or collective anomalies, and are normally very rare; hence, the dataset is largely imbalanced. Additional layers of complexities arise due to the problems of increased dimensionality of modern time series, real-time detection criteria, setting up appropriate detection thresholds, and arriving at results that are interpretable. To embrace these multifaceted challenges, very strong, flexible, and interpretable approaches are required. This paper presents THEMIS, a new framework for time series anomaly detection that exploits pretrained knowledge from foundation models. THEMIS extracts embeddings from the encoder of the Chronos time series foundation model and applies outlier detection techniques like Local Outlier Factor and Spectral Decomposition on the self-similarity matrix, to spot anomalies in the data. Our experiments show that this modular method achieves SOTA results on the MSL dataset and performs quite competitively on the SMAP and SWAT^* datasets. Notably, THEMIS exceeds models trained specifically for anomaly detection, presenting hyperparameter robustness and interpretability by default. This paper advocates for pretrained representations from foundation models for performing efficient and adaptable anomaly detection for time series data.

Respiratory audio, such as coughing and breathing sounds, has predictive power for a wide range of healthcare applications, yet is currently under-explored. The main problem for those applications arises from the difficulty in collecting large labeled task-specific data for model development. Generalizable respiratory acoustic foundation models pretrained with unlabeled data would offer appealing advantages and possibly unlock this impasse. However, given the safety-critical nature of healthcare applications, it is pivotal to also ensure openness and replicability for any proposed foundation model solution. To this end, we introduce OPERA, an OPEn Respiratory Acoustic foundation model pretraining and benchmarking system, as the first approach answering this need. We curate large-scale respiratory audio datasets (~136K samples, 440 hours), pretrain three pioneering foundation models, and build a benchmark consisting of 19 downstream respiratory health tasks for evaluation. Our pretrained models demonstrate superior performance (against existing acoustic models pretrained with general audio on 16 out of 19 tasks) and generalizability (to unseen datasets and new respiratory audio modalities). This highlights the great promise of respiratory acoustic foundation models and encourages more studies using OPERA as an open resource to accelerate research on respiratory audio for health. The system is accessible from https://github.com/evelyn0414/OPERA.

Vision-driven field monitoring is central to digital agriculture, yet models built on general-domain pretrained backbones often fail to generalize across tasks, owing to the interaction of fine, variable canopy structures with fluctuating field conditions. We present FoMo4Wheat, one of the first crop-domain vision foundation model pretrained with self-supervision on ImAg4Wheat, the largest and most diverse wheat image dataset to date (2.5 million high-resolution images collected over a decade at 30 global sites, spanning >2,000 genotypes and >500 environmental conditions). This wheat-specific pretraining yields representations that are robust for wheat and transferable to other crops and weeds. Across ten in-field vision tasks at canopy and organ levels, FoMo4Wheat models consistently outperform state-of-the-art models pretrained on general-domain dataset. These results demonstrate the value of crop-specific foundation models for reliable in-field perception and chart a path toward a universal crop foundation model with cross-species and cross-task capabilities. FoMo4Wheat models and the ImAg4Wheat dataset are publicly available online: https://github.com/PheniX-Lab/FoMo4Wheat and https://huggingface.co/PheniX-Lab/FoMo4Wheat. The demonstration website is: https://fomo4wheat.phenix-lab.com/.

Hyperspectral object tracking using snapshot mosaic cameras is emerging as it provides enhanced spectral information alongside spatial data, contributing to a more comprehensive understanding of material properties. Using transformers, which have consistently outperformed convolutional neural networks (CNNs) in learning better feature representations, would be expected to be effective for Hyperspectral object tracking. However, training large transformers necessitates extensive datasets and prolonged training periods. This is particularly critical for complex tasks like object tracking, and the scarcity of large datasets in the hyperspectral domain acts as a bottleneck in achieving the full potential of powerful transformer models. This paper proposes an effective methodology that adapts large pretrained transformer-based foundation models for hyperspectral object tracking. We propose an adaptive, learnable spatial-spectral token fusion module that can be extended to any transformer-based backbone for learning inherent spatial-spectral features in hyperspectral data. Furthermore, our model incorporates a cross-modality training pipeline that facilitates effective learning across hyperspectral datasets collected with different sensor modalities. This enables the extraction of complementary knowledge from additional modalities, whether or not they are present during testing. Our proposed model also achieves superior performance with minimal training iterations.

Radiology plays an integral role in modern medicine, yet rising imaging volumes have far outpaced workforce growth. Foundation models offer a path toward assisting with the full spectrum of radiology tasks, but existing medical models remain limited: they process volumetric CT and MRI as low-fidelity 2D slices, discard critical grayscale contrast information, and lack evaluation frameworks that reflect real clinical practice. We introduce Pillar-0, a radiology foundation model pretrained on 42,990 abdomen-pelvis CTs, 86,411 chest CTs, 14,348 head CTs, and 11,543 breast MRIs from a large academic center, together with RATE, a scalable framework that extracts structured labels for 366 radiologic findings with near-perfect accuracy using LLMs. Across internal test sets of 14,230 abdomen-pelvis CTs, 10,646 chest CTs, 4,906 head CTs, and 1,585 breast MRIs, Pillar-0 establishes a new performance frontier, achieving mean AUROCs of 86.4, 88.0, 90.1, and 82.9, outperforming MedGemma (Google), MedImageInsight (Microsoft), Lingshu (Alibaba), and Merlin (Stanford) by 7.8-15.8 AUROC points and ranking best in 87.2\% (319/366) tasks. Pillar-0 similarly outperforms all baselines in an external validation on the Stanford Abdominal CT dataset, including Merlin (82.2 vs 80.6 AUROC). Pillar-0 extends to tasks beyond its pretraining, such as long-horizon lung cancer risk prediction, where it improves upon the state-of-the-art Sybil by 3.0 C-index points on NLST, and generalizes with gains of 5.9 (MGH) and 1.9 (CGMH). In brain hemorrhage detection, Pillar-0 obtained a >95 AUROC when using only 1/20th of the data of the next most sample efficient baseline. Pillar-0 and RATE together provide an open, clinically rigorous foundation for building high-performance radiology systems, enabling applications that were previously infeasible due to computational, data, and evaluation constraints.

Due to the limited scale and quality of video-text training corpus, most vision-language foundation models employ image-text datasets for pretraining and primarily focus on modeling visually semantic representations while disregarding temporal semantic representations and correlations. To address this issue, we propose COSA, a COncatenated SAmple pretrained vision-language foundation model. COSA jointly models visual contents and event-level temporal cues using only image-text corpora. We achieve this by sequentially concatenating multiple image-text pairs as inputs for pretraining. This transformation effectively converts existing image-text corpora into a pseudo long-form video-paragraph corpus, enabling richer scene transformations and explicit event-description correspondence. Extensive experiments demonstrate that COSA consistently improves performance across a broad range of downstream tasks, including long-form/short-form video-text tasks and image-text tasks such as retrieval, captioning, and question answering. Notably, COSA achieves state-of-the-art results on various competitive benchmarks. Code and model are released at https://github.com/TXH-mercury/COSA.

Foundation models pretrained on large-scale datasets are revolutionizing the field of computational pathology (CPath). The generalization ability of foundation models is crucial for the success in various downstream clinical tasks. However, current foundation models have only been evaluated on a limited type and number of tasks, leaving their generalization ability and overall performance unclear. To address this gap, we established a most comprehensive benchmark to evaluate the performance of off-the-shelf foundation models across six distinct clinical task types, encompassing a total of 39 specific tasks. Our findings reveal that existing foundation models excel at certain task types but struggle to effectively handle the full breadth of clinical tasks. To improve the generalization of pathology foundation models, we propose a unified knowledge distillation framework consisting of both expert and self knowledge distillation, where the former allows the model to learn from the knowledge of multiple expert models, while the latter leverages self-distillation to enable image representation learning via local-global alignment. Based on this framework, a Generalizable Pathology Foundation Model (GPFM) is pretrained on a large-scale dataset consisting of 190 million images from around 86,000 public H&E whole slides across 34 major tissue types. Evaluated on the established benchmark, GPFM achieves an impressive average rank of 1.36, with 29 tasks ranked 1st, while the the second-best model, UNI, attains an average rank of 2.96, with only 4 tasks ranked 1st. The superior generalization of GPFM demonstrates its exceptional modeling capabilities across a wide range of clinical tasks, positioning it as a new cornerstone for feature representation in CPath.

Rapid progress in computational pathology is increasingly driven by vision foundation models pretrained on vast histopathology datasets. While recent efforts have prioritized training on an ever-larger amount of patches, we take an alternative approach focused on data diversity. Our foundation model, Athena, was initialized from a pretrained model and trained on just 115 million tissue patches, several times fewer than recent histopathology foundation models. Rather than relying on patch volume or complex sampling heuristics, we maximize data diversity by randomly selecting only a moderate number of patches per whole-slide image from our diverse internal repository, which spans multiple countries, institutions, and scanner types. Evaluated on a single patch-level benchmark and four slide-level downstream tasks (two molecular and two morphological), Athena approaches the state-of-the-art and even surpasses several models trained on substantially larger datasets. This indicates that diversity across whole-slide images, rather than patch quantity alone, drives learning in histopathology foundation models.

Cytology is essential for cancer diagnostics and screening due to its minimally invasive nature. However, the development of robust deep learning models for digital cytology is challenging due to the heterogeneity in staining and preparation methods of samples, differences across organs, and the limited availability of large, diverse, annotated datasets. Developing a task-specific model for every cytology application is impractical and non-cytology-specific foundation models struggle to generalize to tasks in this domain where the emphasis is on cell morphology. To address these challenges, we introduce CytoFM, the first cytology self-supervised foundation model. Using iBOT, a self-supervised Vision Transformer (ViT) training framework incorporating masked image modeling and self-distillation, we pretrain CytoFM on a diverse collection of cytology datasets to learn robust, transferable representations. We evaluate CytoFM on multiple downstream cytology tasks, including breast cancer classification and cell type identification, using an attention-based multiple instance learning framework. Our results demonstrate that CytoFM performs better on two out of three downstream tasks than existing foundation models pretrained on histopathology (UNI) or natural images (iBOT-Imagenet). Visualizations of learned representations demonstrate our model is able to attend to cytologically relevant features. Despite a small pre-training dataset, CytoFM's promising results highlight the ability of task-agnostic pre-training approaches to learn robust and generalizable features from cytology data.

Large foundation models pretrained on raw web-scale data are not readily deployable without additional step of extensive alignment to human preferences. Such alignment is typically done by collecting large amounts of pairwise comparisons from humans ("Do you prefer output A or B?") and learning a reward model or a policy with the Bradley-Terry-Luce (BTL) model as a proxy for a human's underlying implicit preferences. These methods generally suffer from assuming a universal preference shared by all humans, which lacks the flexibility of adapting to plurality of opinions and preferences. In this work, we propose PAL, a framework to model human preference complementary to existing pretraining strategies, which incorporates plurality from the ground up. We propose using the ideal point model as a lens to view alignment using preference comparisons. Together with our novel reformulation and using mixture modeling, our framework captures the plurality of population preferences while simultaneously learning a common preference latent space across different preferences, which can few-shot generalize to new, unseen users. Our approach enables us to use the penultimate-layer representation of large foundation models and simple MLP layers to learn reward functions that are on-par with the existing large state-of-the-art reward models, thereby enhancing efficiency of reward modeling significantly. We show that PAL achieves competitive reward model accuracy compared to strong baselines on 1) Language models with Summary dataset ; 2) Image Generative models with Pick-a-Pic dataset ; 3) A new semisynthetic heterogeneous dataset generated using Anthropic Personas. Finally, our experiments also highlight the shortcoming of current preference datasets that are created using rigid rubrics which wash away heterogeneity, and call for more nuanced data collection approaches.

Predicting mortality-related outcomes from images offers the prospect of accessible, noninvasive, and scalable health screening. We present a method that leverages pretrained vision transformer foundation models to estimate remaining lifespan from facial and whole-body images, alongside robust uncertainty quantification. We show that predictive uncertainty varies systematically with the true remaining lifespan, and that this uncertainty can be effectively modeled by learning a Gaussian distribution for each sample. Our approach achieves state-of-the-art mean absolute error (MAE) of 7.48 years on an established Dataset, and further improves to 4.79 and 5.07 years MAE on two new, higher-quality datasets curated and published in this work. Importantly, our models provide well-calibrated uncertainty estimates, as demonstrated by a bucketed expected calibration error of 0.62 years. While not intended for clinical deployment, these results highlight the potential of extracting medically relevant signals from images. We make all code and datasets available to facilitate further research.

We study the problem of posterior sampling using pretrained discrete diffusion foundation models, aiming to recover images from noisy measurements without retraining task-specific models. While diffusion models have achieved remarkable success in generative modeling, most advances rely on continuous Gaussian diffusion. In contrast, discrete diffusion offers a unified framework for jointly modeling categorical data such as text and images. Beyond unification, discrete diffusion provides faster inference, finer control, and principled training-free Bayesian inference, making it particularly well-suited for posterior sampling. However, existing approaches to discrete diffusion posterior sampling face severe challenges: derivative-free guidance yields sparse signals, continuous relaxations limit applicability, and split Gibbs samplers suffer from the curse of dimensionality. To overcome these limitations, we introduce Anchored Posterior Sampling (APS) for masked diffusion foundation models, built on two key innovations -- quantized expectation for gradient-like guidance in discrete embedding space, and anchored remasking for adaptive decoding. Our approach achieves state-of-the-art performance among discrete diffusion samplers across linear and nonlinear inverse problems on the standard benchmarks. We further demonstrate the benefits of our approach in training-free stylization and text-guided editing.

In this paper, we propose VidLA, an approach for video-language alignment at scale. There are two major limitations of previous video-language alignment approaches. First, they do not capture both short-range and long-range temporal dependencies and typically employ complex hierarchical deep network architectures that are hard to integrate with existing pretrained image-text foundation models. To effectively address this limitation, we instead keep the network architecture simple and use a set of data tokens that operate at different temporal resolutions in a hierarchical manner, accounting for the temporally hierarchical nature of videos. By employing a simple two-tower architecture, we are able to initialize our video-language model with pretrained image-text foundation models, thereby boosting the final performance. Second, existing video-language alignment works struggle due to the lack of semantically aligned large-scale training data. To overcome it, we leverage recent LLMs to curate the largest video-language dataset to date with better visual grounding. Furthermore, unlike existing video-text datasets which only contain short clips, our dataset is enriched with video clips of varying durations to aid our temporally hierarchical data tokens in extracting better representations at varying temporal scales. Overall, empirical results show that our proposed approach surpasses state-of-the-art methods on multiple retrieval benchmarks, especially on longer videos, and performs competitively on classification benchmarks.

Designing de-novo molecules with desired property profiles requires efficient exploration of the vast chemical space ranging from 10^{23} to 10^{60} possible synthesizable candidates. While various deep generative models have been developed to design small molecules using diverse input representations, Molecular Large Language Models (Mol-LLMs) based on string representations have emerged as a scalable approach capable of exploring billions of molecules. However, there remains limited understanding regarding how standard language modeling practices such as textual representations, tokenization strategies, model size, and dataset scale impact molecular generation performance. In this work, we systematically investigate these critical aspects by introducing NovoMolGen, a family of transformer-based foundation models pretrained on 1.5 billion molecules for de-novo molecule generation. Through extensive empirical analyses, we identify a weak correlation between performance metrics measured during pretraining and actual downstream performance, revealing important distinctions between molecular and general NLP training dynamics. NovoMolGen establishes new state-of-the-art results, substantially outperforming prior Mol-LLMs and specialized generative models in both unconstrained and goal-directed molecular generation tasks, thus providing a robust foundation for advancing efficient and effective molecular modeling strategies.

Time series forecasting is a foundational task across domains, such as finance, healthcare, and environmental monitoring. While recent advances in Time Series Foundation Models (TSFMs) have demonstrated strong generalisation through large-scale pretraining, existing models operate predominantly in a unimodal setting, ignoring the rich multimodal context, such as visual and textual signals, that often accompanies time series data in real-world scenarios. This paper introduces a novel parameter-efficient multimodal framework, UniCast, that extends TSFMs to jointly leverage time series, vision, and text modalities for enhanced forecasting performance. Our method integrates modality-specific embeddings from pretrained Vision and Text Encoders with a frozen TSFM via soft prompt tuning, enabling efficient adaptation with minimal parameter updates. This design not only preserves the generalisation strength of the foundation model but also enables effective cross-modal interaction. Extensive experiments across diverse time-series forecasting benchmarks demonstrate that UniCast consistently and significantly outperforms all existing TSFM baselines. The findings highlight the critical role of multimodal context in advancing the next generation of general-purpose time series forecasters.

Referring video object segmentation (RVOS) aims to segment target objects throughout a video based on a text description. Despite notable progress in recent years, current RVOS models remain struggle to handle complicated object descriptions due to their limited video-language understanding. To address this limitation, we present ReferDINO, an end-to-end RVOS model that inherits strong vision-language understanding from the pretrained visual grounding foundation models, and is further endowed with effective temporal understanding and object segmentation capabilities. In ReferDINO, we contribute three technical innovations for effectively adapting the foundation models to RVOS: 1) an object-consistent temporal enhancer that capitalizes on the pretrained object-text representations to enhance temporal understanding and object consistency; 2) a grounding-guided deformable mask decoder that integrates text and grounding conditions to generate accurate object masks; 3) a confidence-aware query pruning strategy that significantly improves the object decoding efficiency without compromising performance. We conduct extensive experiments on five public RVOS benchmarks to demonstrate that our proposed ReferDINO outperforms state-of-the-art methods significantly. Project page: https://isee-laboratory.github.io/ReferDINO

3D geometric information is essential for manipulation tasks, as robots need to perceive the 3D environment, reason about spatial relationships, and interact with intricate spatial configurations. Recent research has increasingly focused on the explicit extraction of 3D features, while still facing challenges such as the lack of large-scale robotic 3D data and the potential loss of spatial geometry. To address these limitations, we propose the Lift3D framework, which progressively enhances 2D foundation models with implicit and explicit 3D robotic representations to construct a robust 3D manipulation policy. Specifically, we first design a task-aware masked autoencoder that masks task-relevant affordance patches and reconstructs depth information, enhancing the 2D foundation model's implicit 3D robotic representation. After self-supervised fine-tuning, we introduce a 2D model-lifting strategy that establishes a positional mapping between the input 3D points and the positional embeddings of the 2D model. Based on the mapping, Lift3D utilizes the 2D foundation model to directly encode point cloud data, leveraging large-scale pretrained knowledge to construct explicit 3D robotic representations while minimizing spatial information loss. In experiments, Lift3D consistently outperforms previous state-of-the-art methods across several simulation benchmarks and real-world scenarios.

Time series foundation models (TSFMs) have recently gained significant attention due to their strong zero-shot capabilities and widespread real-world applications. Such models typically require a computationally costly pretraining on large-scale, carefully curated collections of real-world sequences. To allow for a sample-efficient pretraining of TSFMs, we propose CauKer, a novel algorithm designed to generate diverse, causally coherent synthetic time series with realistic trends, seasonality, and nonlinear interactions. CauKer combines Gaussian Process (GP) kernel composition with Structural Causal Models (SCM) to produce data for sample-efficient pretraining of state-of-the-art classification TSFMs having different architectures and following different pretraining approaches. Additionally, our experiments reveal that CauKer-generated datasets exhibit clear scaling laws for both dataset size (10K to 10M samples) and model capacity (1M to 783M parameters), unlike real-world datasets, which display irregular scaling behavior.

Accurate segmentation of organs and tumors in CT and MRI scans is essential for diagnosis, treatment planning, and disease monitoring. While deep learning has advanced automated segmentation, most models remain task-specific, lacking generalizability across modalities and institutions. Vision foundation models (FMs) pretrained on billion-scale natural images offer powerful and transferable representations. However, adapting them to medical imaging faces two key challenges: (1) the ViT backbone of most foundation models still underperform specialized CNNs on medical image segmentation, and (2) the large domain gap between natural and medical images limits transferability. We introduce MedDINOv3, a simple and effective framework for adapting DINOv3 to medical segmentation. We first revisit plain ViTs and design a simple and effective architecture with multi-scale token aggregation. Then, we perform domain-adaptive pretraining on CT-3M, a curated collection of 3.87M axial CT slices, using a multi-stage DINOv3 recipe to learn robust dense features. MedDINOv3 matches or exceeds state-of-the-art performance across four segmentation benchmarks, demonstrating the potential of vision foundation models as unified backbones for medical image segmentation. The code is available at https://github.com/ricklisz/MedDINOv3.

Large pretrained models such as GPT-3 have had tremendous impact on modern natural language processing by leveraging self-supervised learning to learn salient representations that can be used to readily finetune on a wide variety of downstream tasks. We investigate the possibility of transferring such advances to molecular machine learning by building a chemical foundation model, ChemBERTa-2, using the language of SMILES. While labeled data for molecular prediction tasks is typically scarce, libraries of SMILES strings are readily available. In this work, we build upon ChemBERTa by optimizing the pretraining process. We compare multi-task and self-supervised pretraining by varying hyperparameters and pretraining dataset size, up to 77M compounds from PubChem. To our knowledge, the 77M set constitutes one of the largest datasets used for molecular pretraining to date. We find that with these pretraining improvements, we are competitive with existing state-of-the-art architectures on the MoleculeNet benchmark suite. We analyze the degree to which improvements in pretraining translate to improvement on downstream tasks.

We introduce Poseidon, a foundation model for learning the solution operators of PDEs. It is based on a multiscale operator transformer, with time-conditioned layer norms that enable continuous-in-time evaluations. A novel training strategy leveraging the semi-group property of time-dependent PDEs to allow for significant scaling-up of the training data is also proposed. Poseidon is pretrained on a diverse, large scale dataset for the governing equations of fluid dynamics. It is then evaluated on a suite of 15 challenging downstream tasks that include a wide variety of PDE types and operators. We show that Poseidon exhibits excellent performance across the board by outperforming baselines significantly, both in terms of sample efficiency and accuracy. Poseidon also generalizes very well to new physics that is not seen during pretraining. Moreover, Poseidon scales with respect to model and data size, both for pretraining and for downstream tasks. Taken together, our results showcase the surprising ability of Poseidon to learn effective representations from a very small set of PDEs during pretraining in order to generalize well to unseen and unrelated PDEs downstream, demonstrating its potential as an effective, general purpose PDE foundation model. Finally, the Poseidon model as well as underlying pretraining and downstream datasets are open sourced, with code being available at https://github.com/camlab-ethz/poseidon and pretrained models and datasets at https://huggingface.co/camlab-ethz.

Pretrained transformers readily adapt to new sequence modeling tasks via zero-shot prompting, but relational domains still lack architectures that transfer across datasets and tasks. The core challenge is the diversity of relational data, with varying heterogeneous schemas, graph structures and functional dependencies. In this paper, we present the Relational Transformer (RT) architecture, which can be pretrained on diverse relational databases and directly applied to unseen datasets and tasks without task- or dataset-specific fine-tuning, or retrieval of in-context examples. RT (i) tokenizes cells with table/column metadata, (ii) is pretrained via masked token prediction, and (iii) utilizes a novel Relational Attention mechanism over columns, rows, and primary-foreign key links. Pretrained on RelBench datasets spanning tasks such as churn and sales forecasting, RT attains strong zero-shot performance, averaging 94% of fully supervised AUROC on binary classification tasks with a single forward pass of a 22M parameter model, as opposed to 84% for a 27B LLM. Fine-tuning yields state-of-the-art results with high sample efficiency. Our experiments show that RT's zero-shot transfer harnesses task-table context, relational attention patterns and schema semantics. Overall, RT provides a practical path toward foundation models for relational data.

Hospitals and healthcare systems rely on operational decisions that determine patient flow, cost, and quality of care. Despite strong performance on medical knowledge and conversational benchmarks, foundation models trained on general text may lack the specialized knowledge required for these operational decisions. We introduce Lang1, a family of models (100M-7B parameters) pretrained on a specialized corpus blending 80B clinical tokens from NYU Langone Health's EHRs and 627B tokens from the internet. To rigorously evaluate Lang1 in real-world settings, we developed the REalistic Medical Evaluation (ReMedE), a benchmark derived from 668,331 EHR notes that evaluates five critical tasks: 30-day readmission prediction, 30-day mortality prediction, length of stay, comorbidity coding, and predicting insurance claims denial. In zero-shot settings, both general-purpose and specialized models underperform on four of five tasks (36.6%-71.7% AUROC), with mortality prediction being an exception. After finetuning, Lang1-1B outperforms finetuned generalist models up to 70x larger and zero-shot models up to 671x larger, improving AUROC by 3.64%-6.75% and 1.66%-23.66% respectively. We also observed cross-task scaling with joint finetuning on multiple tasks leading to improvement on other tasks. Lang1-1B effectively transfers to out-of-distribution settings, including other clinical tasks and an external health system. Our findings suggest that predictive capabilities for hospital operations require explicit supervised finetuning, and that this finetuning process is made more efficient by in-domain pretraining on EHR. Our findings support the emerging view that specialized LLMs can compete with generalist models in specialized tasks, and show that effective healthcare systems AI requires the combination of in-domain pretraining, supervised finetuning, and real-world evaluation beyond proxy benchmarks.

We introduce the Yi model family, a series of language and multimodal models that demonstrate strong multi-dimensional capabilities. The Yi model family is based on 6B and 34B pretrained language models, then we extend them to chat models, 200K long context models, depth-upscaled models, and vision-language models. Our base models achieve strong performance on a wide range of benchmarks like MMLU, and our finetuned chat models deliver strong human preference rate on major evaluation platforms like AlpacaEval and Chatbot Arena. Building upon our scalable super-computing infrastructure and the classical transformer architecture, we attribute the performance of Yi models primarily to its data quality resulting from our data-engineering efforts. For pretraining, we construct 3.1 trillion tokens of English and Chinese corpora using a cascaded data deduplication and quality filtering pipeline. For finetuning, we polish a small scale (less than 10K) instruction dataset over multiple iterations such that every single instance has been verified directly by our machine learning engineers. For vision-language, we combine the chat language model with a vision transformer encoder and train the model to align visual representations to the semantic space of the language model. We further extend the context length to 200K through lightweight continual pretraining and demonstrate strong needle-in-a-haystack retrieval performance. We show that extending the depth of the pretrained checkpoint through continual pretraining further improves performance. We believe that given our current results, continuing to scale up model parameters using thoroughly optimized data will lead to even stronger frontier models.

Over the past years, foundation models have caused a paradigm shift in machine learning due to their unprecedented capabilities for zero-shot and few-shot generalization. However, despite the success of foundation models in modalities such as natural language processing and computer vision, the development of foundation models for time series forecasting has lagged behind. We present Lag-Llama, a general-purpose foundation model for univariate probabilistic time series forecasting based on a decoder-only transformer architecture that uses lags as covariates. Lag-Llama is pretrained on a large corpus of diverse time series data from several domains, and demonstrates strong zero-shot generalization capabilities compared to a wide range of forecasting models on downstream datasets across domains. Moreover, when fine-tuned on relatively small fractions of such previously unseen datasets, Lag-Llama achieves state-of-the-art performance, outperforming prior deep learning approaches, emerging as the best general-purpose model on average. Lag-Llama serves as a strong contender to the current state-of-art in time series forecasting and paves the way for future advancements in foundation models tailored to time series data.

Recent advances in self-supervised learning for Vision Transformers (ViTs) have fueled breakthroughs in remote sensing (RS) foundation models. However, the quadratic complexity of self-attention poses a significant barrier to scalability, particularly for large models and high-resolution images. While the linear-complexity Mamba architecture offers a promising alternative, existing RS applications of Mamba remain limited to supervised tasks on small, domain-specific datasets. To address these challenges, we propose RoMA, a framework that enables scalable self-supervised pretraining of Mamba-based RS foundation models using large-scale, diverse, unlabeled data. RoMA enhances scalability for high-resolution images through a tailored auto-regressive learning strategy, incorporating two key innovations: 1) a rotation-aware pretraining mechanism combining adaptive cropping with angular embeddings to handle sparsely distributed objects with arbitrary orientations, and 2) multi-scale token prediction objectives that address the extreme variations in object scales inherent to RS imagery. Systematic empirical studies validate that Mamba adheres to RS data and parameter scaling laws, with performance scaling reliably as model and data size increase. Furthermore, experiments across scene classification, object detection, and semantic segmentation tasks demonstrate that RoMA-pretrained Mamba models consistently outperform ViT-based counterparts in both accuracy and computational efficiency. The source code and pretrained models will be released at https://github.com/MiliLab/RoMA.

To tackle the prevalence of pseudo changes, the scarcity of labeled samples, and the difficulty of cross-domain generalization in multi-temporal and multi-source remote sensing imagery, we propose PeftCD, a change detection framework built upon Vision Foundation Models (VFMs) with Parameter-Efficient Fine-Tuning (PEFT). At its core, PeftCD employs a weight-sharing Siamese encoder derived from a VFM, into which LoRA and Adapter modules are seamlessly integrated. This design enables highly efficient task adaptation by training only a minimal set of additional parameters. To fully unlock the potential of VFMs, we investigate two leading backbones: the Segment Anything Model v2 (SAM2), renowned for its strong segmentation priors, and DINOv3, a state-of-the-art self-supervised representation learner. The framework is complemented by a deliberately lightweight decoder, ensuring the focus remains on the powerful feature representations from the backbones. Extensive experiments demonstrate that PeftCD achieves state-of-the-art performance across multiple public datasets, including SYSU-CD (IoU 73.81%), WHUCD (92.05%), MSRSCD (64.07%), MLCD (76.89%), CDD (97.01%), S2Looking (52.25%) and LEVIR-CD (85.62%), with notably precise boundary delineation and strong suppression of pseudo-changes. In summary, PeftCD presents an optimal balance of accuracy, efficiency, and generalization. It offers a powerful and scalable paradigm for adapting large-scale VFMs to real-world remote sensing change detection applications. The code and pretrained models will be released at https://github.com/dyzy41/PeftCD.

Humans effortlessly interpret images by parsing them into part-whole hierarchies; deep learning excels in learning multi-level feature spaces, but they often lack explicit coding of part-whole relations, a prominent property of medical imaging. To overcome this limitation, we introduce Adam-v2, a new self-supervised learning framework extending Adam [79] by explicitly incorporating part-whole hierarchies into its learning objectives through three key branches: (1) Localizability, acquiring discriminative representations to distinguish different anatomical patterns; (2) Composability, learning each anatomical structure in a parts-to-whole manner; and (3) Decomposability, comprehending each anatomical structure in a whole-to-parts manner. Experimental results across 10 tasks, compared to 11 baselines in zero-shot, few-shot transfer, and full fine-tuning settings, showcase Adam-v2's superior performance over large-scale medical models and existing SSL methods across diverse downstream tasks. The higher generality and robustness of Adam-v2's representations originate from its explicit construction of hierarchies for distinct anatomical structures from unlabeled medical images. Adam-v2 preserves a semantic balance of anatomical diversity and harmony in its embedding, yielding representations that are both generic and semantically meaningful, yet overlooked in existing SSL methods. All code and pretrained models are available at https://github.com/JLiangLab/Eden.

We investigate how both the adaptation of a generic foundation model via transfer learning and the integration of complementary modalities from the operating room (OR) can support surgical data science. To this end, we use V-JEPA as the single-modality foundation of a multimodal model for minimally invasive surgery support. We analyze how the model's downstream performance can benefit (a) from finetuning on unlabeled surgical video data and (b) from providing additional time-resolved data streams from the OR in a multimodal setup. In an in-house dataset of liver surgery videos, we analyze the tasks of predicting hospital length of stay and postoperative complications. In videos of the public HeiCo dataset, we analyze the task of surgical phase recognition. As a baseline, we apply pretrained V-JEPA to all tasks. We then finetune it on unlabeled, held-out videos to investigate its change in performance after domain adaptation. Following the idea of modular decision support networks, we integrate additional data streams from the OR by training a separate encoder to form a shared representation space with V-JEPA's embeddings. Our experiments show that finetuning on domain-specific data increases model performance. On the in-house data, integrating additional time-resolved data likewise benefits the model. On the HeiCo data, accuracy of the pretrained video-only, single-modality baseline setup is on par with the top-performing submissions of the EndoVis2017 challenge, while finetuning on domain-specific data increases accuracy further. Our results thus demonstrate how surgical data science can leverage public, generic foundation models. Likewise, they indicate the potential of domain adaptation and of integrating suitable complementary data streams from the OR. To support further research, we release our code and model weights at https://github.com/DigitalSurgeryLab-Basel/ML-CDS-2025.

Foundation multi-modal models are often designed by stitching of multiple existing pretrained uni-modal models: for example, an image classifier with an text model. This stitching process is performed by training a connector module that aims to align the representation spaces of these uni-modal models towards a multi-modal objective. However, given the complexity of training such connectors on large scale web-based datasets coupled with the ever-increasing number of available pretrained uni-modal models, the task of uni-modal models selection and subsequent connector module training becomes computationally demanding. To address this under-studied critical problem, we propose Hypernetwork Model Alignment (Hyma), a novel all-in-one solution for optimal uni-modal model selection and connector training by leveraging hypernetworks. Specifically, our framework utilizes the parameter prediction capability of a hypernetwork to obtain jointly trained connector modules for N times M combinations of uni-modal models. In our experiments, Hyma reduces the cost of searching for the best performing uni-modal model pair by 10times, while matching the ranking and trained connector performance obtained via grid search across a suite of diverse multi-modal benchmarks.

Earth observation (EO) data, collected from diverse sensors with varying imaging principles, present significant challenges in creating unified analytical frameworks. We present GeoLangBind, a novel agglomerative vision--language foundation model that bridges the gap between heterogeneous EO data modalities using language as a unifying medium. Our approach aligns different EO data types into a shared language embedding space, enabling seamless integration and complementary feature learning from diverse sensor data. To achieve this, we construct a large-scale multimodal image--text dataset, GeoLangBind-2M, encompassing six data modalities. GeoLangBind leverages this dataset to develop a zero-shot foundation model capable of processing arbitrary numbers of EO data channels as input. Through our designed Modality-aware Knowledge Agglomeration (MaKA) module and progressive multimodal weight merging strategy, we create a powerful agglomerative foundation model that excels in both zero-shot vision--language comprehension and fine-grained visual understanding. Extensive evaluation across 23 datasets covering multiple tasks demonstrates GeoLangBind's superior performance and versatility in EO applications, offering a robust framework for various environmental monitoring and analysis tasks. The dataset and pretrained models will be publicly available.

With the exacerbation of the biodiversity and climate crises, macroecological pursuits such as global biodiversity mapping become more urgent. Remote sensing offers a wealth of Earth observation data for ecological studies, but the scarcity of labeled datasets remains a major challenge. Recently, self-supervised learning has enabled learning representations from unlabeled data, triggering the development of pretrained geospatial models with generalizable features. However, these models are often trained on datasets biased toward areas of high human activity, leaving entire ecological regions underrepresented. Additionally, while some datasets attempt to address seasonality through multi-date imagery, they typically follow calendar seasons rather than local phenological cycles. To better capture vegetation seasonality at a global scale, we propose a simple phenology-informed sampling strategy and introduce corresponding SSL4Eco, a multi-date Sentinel-2 dataset, on which we train an existing model with a season-contrastive objective. We compare representations learned from SSL4Eco against other datasets on diverse ecological downstream tasks and demonstrate that our straightforward sampling method consistently improves representation quality, highlighting the importance of dataset construction. The model pretrained on SSL4Eco reaches state of the art performance on 7 out of 8 downstream tasks spanning (multi-label) classification and regression. We release our code, data, and model weights to support macroecological and computer vision research at https://github.com/PlekhanovaElena/ssl4eco.

We introduce [Cosmos-Predict2.5], the latest generation of the Cosmos World Foundation Models for Physical AI. Built on a flow-based architecture, [Cosmos-Predict2.5] unifies Text2World, Image2World, and Video2World generation in a single model and leverages [Cosmos-Reason1], a Physical AI vision-language model, to provide richer text grounding and finer control of world simulation. Trained on 200M curated video clips and refined with reinforcement learning-based post-training, [Cosmos-Predict2.5] achieves substantial improvements over [Cosmos-Predict1] in video quality and instruction alignment, with models released at 2B and 14B scales. These capabilities enable more reliable synthetic data generation, policy evaluation, and closed-loop simulation for robotics and autonomous systems. We further extend the family with [Cosmos-Transfer2.5], a control-net style framework for Sim2Real and Real2Real world translation. Despite being 3.5times smaller than [Cosmos-Transfer1], it delivers higher fidelity and robust long-horizon video generation. Together, these advances establish [Cosmos-Predict2.5] and [Cosmos-Transfer2.5] as versatile tools for scaling embodied intelligence. To accelerate research and deployment in Physical AI, we release source code, pretrained checkpoints, and curated benchmarks under the NVIDIA Open Model License at https://github.com/nvidia-cosmos/cosmos-predict2.5 and https://github.com/nvidia-cosmos/cosmos-transfer2.5. We hope these open resources lower the barrier to adoption and foster innovation in building the next generation of embodied intelligence.

We present NovaCOMET, an open commonsense knowledge model, that combines the best aspects of knowledge and general task models. Compared to previous knowledge models, NovaCOMET allows open-format relations enabling direct application to reasoning tasks; compared to general task models like Flan-T5, it explicitly centers knowledge, enabling superior performance for commonsense reasoning. NovaCOMET leverages the knowledge of opaque proprietary models to create an open knowledge pipeline. First, knowledge is symbolically distilled into NovATOMIC, a publicly-released discrete knowledge graph which can be audited, critiqued, and filtered. Next, we train NovaCOMET on NovATOMIC by fine-tuning an open-source pretrained model. NovaCOMET uses an open-format training objective, replacing the fixed relation sets of past knowledge models, enabling arbitrary structures within the data to serve as inputs or outputs. The resulting generation model, optionally augmented with human annotation, matches or exceeds comparable open task models like Flan-T5 on a range of commonsense generation tasks. NovaCOMET serves as a counterexample to the contemporary focus on instruction tuning only, demonstrating a distinct advantage to explicitly modeling commonsense knowledge as well.

In this paper, we propose VideoLLaMA3, a more advanced multimodal foundation model for image and video understanding. The core design philosophy of VideoLLaMA3 is vision-centric. The meaning of "vision-centric" is two-fold: the vision-centric training paradigm and vision-centric framework design. The key insight of our vision-centric training paradigm is that high-quality image-text data is crucial for both image and video understanding. Instead of preparing massive video-text datasets, we focus on constructing large-scale and high-quality image-text datasets. VideoLLaMA3 has four training stages: 1) vision-centric alignment stage, which warms up the vision encoder and projector; 2) vision-language pretraining stage, which jointly tunes the vision encoder, projector, and LLM with large-scale image-text data covering multiple types (including scene images, documents, charts) as well as text-only data. 3) multi-task fine-tuning stage, which incorporates image-text SFT data for downstream tasks and video-text data to establish a foundation for video understanding. 4) video-centric fine-tuning, which further improves the model's capability in video understanding. As for the framework design, to better capture fine-grained details in images, the pretrained vision encoder is adapted to encode images of varying sizes into vision tokens with corresponding numbers, rather than a fixed number of tokens. For video inputs, we reduce the number of vision tokens according to their similarity so that the representation of videos will be more precise and compact. Benefit from vision-centric designs, VideoLLaMA3 achieves compelling performances in both image and video understanding benchmarks.

We explore the impact of parameter sparsity on the scaling behavior of Transformers trained on massive datasets (i.e., "foundation models"), in both vision and language domains. In this setting, we identify the first scaling law describing the relationship between weight sparsity, number of non-zero parameters, and amount of training data, which we validate empirically across model and data scales; on ViT/JFT-4B and T5/C4. These results allow us to characterize the "optimal sparsity", the sparsity level which yields the best performance for a given effective model size and training budget. For a fixed number of non-zero parameters, we identify that the optimal sparsity increases with the amount of data used for training. We also extend our study to different sparsity structures (such as the hardware-friendly n:m pattern) and strategies (such as starting from a pretrained dense model). Our findings shed light on the power and limitations of weight sparsity across various parameter and computational settings, offering both theoretical understanding and practical implications for leveraging sparsity towards computational efficiency improvements.

Complex 3D scene understanding has gained increasing attention, with scene encoding strategies playing a crucial role in this success. However, the optimal scene encoding strategies for various scenarios remain unclear, particularly compared to their image-based counterparts. To address this issue, we present a comprehensive study that probes various visual encoding models for 3D scene understanding, identifying the strengths and limitations of each model across different scenarios. Our evaluation spans seven vision foundation encoders, including image-based, video-based, and 3D foundation models. We evaluate these models in four tasks: Vision-Language Scene Reasoning, Visual Grounding, Segmentation, and Registration, each focusing on different aspects of scene understanding. Our evaluations yield key findings: DINOv2 demonstrates superior performance, video models excel in object-level tasks, diffusion models benefit geometric tasks, and language-pretrained models show unexpected limitations in language-related tasks. These insights challenge some conventional understandings, provide novel perspectives on leveraging visual foundation models, and highlight the need for more flexible encoder selection in future vision-language and scene-understanding tasks.

Since the seminal work of TabPFN, research on tabular foundation models (TFMs) based on in-context learning (ICL) has challenged long-standing paradigms in machine learning. Without seeing any real-world data, models pretrained on purely synthetic datasets generalize remarkably well across diverse datasets, often using only a moderate number of in-context examples. This shifts the focus in tabular machine learning from model architecture design to the design of synthetic datasets, or, more precisely, to the prior distributions that generate them. Yet the guiding principles for prior design remain poorly understood. This work marks the first attempt to address the gap. We systematically investigate and identify key properties of synthetic priors that allow pretrained TFMs to generalize well. Based on these insights, we introduce Mitra, a TFM trained on a curated mixture of synthetic priors selected for their diversity, distinctiveness, and performance on real-world tabular data. Mitra consistently outperforms state-of-the-art TFMs, such as TabPFNv2 and TabICL, across both classification and regression benchmarks, with better sample efficiency.

Transcriptomic foundation models (TFMs) have recently emerged as powerful tools for analyzing gene expression in cells and tissues, supporting key tasks such as cell-type annotation, batch correction, and perturbation prediction. However, the diversity of model implementations and training strategies across recent TFMs, though promising, makes it challenging to isolate the contribution of individual design choices or evaluate their potential synergies. This hinders the field's ability to converge on best practices and limits the reproducibility of insights across studies. We present BMFM-RNA, an open-source, modular software package that unifies diverse TFM pretraining and fine-tuning objectives within a single framework. Leveraging this capability, we introduce a novel training objective, whole cell expression decoder (WCED), which captures global expression patterns using an autoencoder-like CLS bottleneck representation. In this paper, we describe the framework, supported input representations, and training objectives. We evaluated four model checkpoints pretrained on CELLxGENE using combinations of masked language modeling (MLM), WCED and multitask learning. Using the benchmarking capabilities of BMFM-RNA, we show that WCED-based models achieve performance that matches or exceeds state-of-the-art approaches like scGPT across more than a dozen datasets in both zero-shot and fine-tuning tasks. BMFM-RNA, available as part of the biomed-multi-omics project ( https://github.com/BiomedSciAI/biomed-multi-omic ), offers a reproducible foundation for systematic benchmarking and community-driven exploration of optimal TFM training strategies, enabling the development of more effective tools to leverage the latest advances in AI for understanding cell biology.

Foundation models have emerged as a powerful tool for many AI problems. Despite the tremendous success of foundation models, effective adaptation to new tasks, particularly those with limited labels, remains an open question and lacks theoretical understanding. An emerging solution with recent success in vision and NLP involves finetuning a foundation model on a selection of relevant tasks, before its adaptation to a target task with limited labeled samples. In this paper, we study the theoretical justification of this multitask finetuning approach. Our theoretical analysis reveals that with a diverse set of related tasks, this multitask finetuning leads to reduced error in the target task, in comparison to directly adapting the same pretrained model. We quantify the relationship between finetuning tasks and target tasks by diversity and consistency metrics, and further propose a practical task selection algorithm. We substantiate our theoretical claims with extensive empirical evidence. Further, we present results affirming our task selection algorithm adeptly chooses related finetuning tasks, providing advantages to the model performance on target tasks. We believe our study shed new light on the effective adaptation of foundation models to new tasks that lack abundant labels. Our code is available at https://github.com/OliverXUZY/Foudation-Model_Multitask.

Humans can perceive and reason about spatial relationships from sequential visual observations, such as egocentric video streams. However, how pretrained models acquire such abilities, especially high-level reasoning, remains unclear. This paper introduces Embodied-R, a collaborative framework combining large-scale Vision-Language Models (VLMs) for perception and small-scale Language Models (LMs) for reasoning. Using Reinforcement Learning (RL) with a novel reward system considering think-answer logical consistency, the model achieves slow-thinking capabilities with limited computational resources. After training on only 5k embodied video samples, Embodied-R with a 3B LM matches state-of-the-art multimodal reasoning models (OpenAI-o1, Gemini-2.5-pro) on both in-distribution and out-of-distribution embodied spatial reasoning tasks. Embodied-R also exhibits emergent thinking patterns such as systematic analysis and contextual integration. We further explore research questions including response length, training on VLM, strategies for reward design, and differences in model generalization after SFT (Supervised Fine-Tuning) and RL training.

Agglomerative models have recently emerged as a powerful approach to training vision foundation models, leveraging multi-teacher distillation from existing models such as CLIP, DINO, and SAM. This strategy enables the efficient creation of robust models, combining the strengths of individual teachers while significantly reducing computational and resource demands. In this paper, we thoroughly analyze state-of-the-art agglomerative models, identifying critical challenges including resolution mode shifts, teacher imbalance, idiosyncratic teacher artifacts, and an excessive number of output tokens. To address these issues, we propose several novel solutions: multi-resolution training, mosaic augmentation, and improved balancing of teacher loss functions. Specifically, in the context of Vision Language Models, we introduce a token compression technique to maintain high-resolution information within a fixed token count. We release our top-performing models, available in multiple scales (-B, -L, -H, and -g), alongside inference code and pretrained weights.

Building artificial intelligence (AI) systems on top of a set of foundation models (FMs) is becoming a new paradigm in AI research. Their representative and generative abilities learnt from vast amounts of data can be easily adapted and transferred to a wide range of downstream tasks without extra training from scratch. However, leveraging FMs in cross-modal generation remains under-researched when audio modality is involved. On the other hand, automatically generating semantically-relevant sound from visual input is an important problem in cross-modal generation studies. To solve this vision-to-audio (V2A) generation problem, existing methods tend to design and build complex systems from scratch using modestly sized datasets. In this paper, we propose a lightweight solution to this problem by leveraging foundation models, specifically CLIP, CLAP, and AudioLDM. We first investigate the domain gap between the latent space of the visual CLIP and the auditory CLAP models. Then we propose a simple yet effective mapper mechanism (V2A-Mapper) to bridge the domain gap by translating the visual input between CLIP and CLAP spaces. Conditioned on the translated CLAP embedding, pretrained audio generative FM AudioLDM is adopted to produce high-fidelity and visually-aligned sound. Compared to previous approaches, our method only requires a quick training of the V2A-Mapper. We further analyze and conduct extensive experiments on the choice of the V2A-Mapper and show that a generative mapper is better at fidelity and variability (FD) while a regression mapper is slightly better at relevance (CS). Both objective and subjective evaluation on two V2A datasets demonstrate the superiority of our proposed method compared to current state-of-the-art approaches - trained with 86% fewer parameters but achieving 53% and 19% improvement in FD and CS, respectively.

Foundation models pre-trained on large-scale natural image datasets offer a powerful paradigm for medical image segmentation. However, effectively transferring their learned representations for precise clinical applications remains a challenge. In this work, we propose Dino U-Net, a novel encoder-decoder architecture designed to exploit the high-fidelity dense features of the DINOv3 vision foundation model. Our architecture introduces an encoder built upon a frozen DINOv3 backbone, which employs a specialized adapter to fuse the model's rich semantic features with low-level spatial details. To preserve the quality of these representations during dimensionality reduction, we design a new fidelity-aware projection module (FAPM) that effectively refines and projects the features for the decoder. We conducted extensive experiments on seven diverse public medical image segmentation datasets. Our results show that Dino U-Net achieves state-of-the-art performance, consistently outperforming previous methods across various imaging modalities. Our framework proves to be highly scalable, with segmentation accuracy consistently improving as the backbone model size increases up to the 7-billion-parameter variant. The findings demonstrate that leveraging the superior, dense-pretrained features from a general-purpose foundation model provides a highly effective and parameter-efficient approach to advance the accuracy of medical image segmentation. The code is available at https://github.com/yifangao112/DinoUNet.

Vision foundation models (FMs) are accelerating the development of digital pathology algorithms and transforming biomedical research. These models learn, in a self-supervised manner, to represent histological features in highly heterogeneous tiles extracted from whole-slide images (WSIs) of real-world patient samples. The performance of these FMs is significantly influenced by the size, diversity, and balance of the pre-training data. However, data selection has been primarily guided by expert knowledge at the WSI level, focusing on factors such as disease classification and tissue types, while largely overlooking the granular details available at the tile level. In this paper, we investigate the potential of unsupervised automatic data curation at the tile-level, taking into account 350 million tiles. Specifically, we apply hierarchical clustering trees to pre-extracted tile embeddings, allowing us to sample balanced datasets uniformly across the embedding space of the pretrained FM. We further identify these datasets are subject to a trade-off between size and balance, potentially compromising the quality of representations learned by FMs, and propose tailored batch sampling strategies to mitigate this effect. We demonstrate the effectiveness of our method through improved performance on a diverse range of clinically relevant downstream tasks.

In this work, we discuss evaluating video foundation models in a fair and robust manner. Unlike language or image foundation models, many video foundation models are evaluated with differing parameters (such as sampling rate, number of frames, pretraining steps, etc.), making fair and robust comparisons challenging. Therefore, we present a carefully designed evaluation framework for measuring two core capabilities of video comprehension: appearance and motion understanding. Our findings reveal that existing video foundation models, whether text-supervised like UMT or InternVideo2, or self-supervised like V-JEPA, exhibit limitations in at least one of these capabilities. As an alternative, we introduce TWLV-I, a new video foundation model that constructs robust visual representations for both motion- and appearance-based videos. Based on the average top-1 accuracy of linear probing on five action recognition benchmarks, pretrained only on publicly accessible datasets, our model shows a 4.6%p improvement compared to V-JEPA (ViT-L) and a 7.7%p improvement compared to UMT (ViT-L). Even when compared to much larger models, our model demonstrates a 7.2%p improvement compared to DFN (ViT-H), a 2.7%p improvement compared to V-JEPA~(ViT-H) and a 2.8%p improvement compared to InternVideo2 (ViT-g). We provide embedding vectors obtained by TWLV-I from videos of several commonly used video benchmarks, along with evaluation source code that can directly utilize these embeddings. The code is available on "https://github.com/twelvelabs-io/video-embeddings-evaluation-framework".

Low-Rank Adaptation (LoRA) is a popular technique for efficient fine-tuning of foundation models. However, applying LoRA in federated learning environments, where data is distributed across multiple clients, presents unique challenges. Existing methods rely on traditional federated averaging of LoRA adapters, resulting in inexact updates. To address this, we propose Federated Exact LoRA, or FedEx-LoRA, which adds a residual error term to the pretrained frozen weight matrix. Our approach achieves exact updates with minimal computational and communication overhead, preserving LoRA's efficiency. We evaluate the method on various models across arithmetic reasoning, commonsense reasoning, natural language understanding and natural language generation tasks, showing consistent performance gains over state-of-the-art methods across multiple settings. Through extensive analysis, we quantify that the deviations in updates from the ideal solution are significant, highlighting the need for exact aggregation. Our method's simplicity, efficiency, and broad applicability position it as a promising solution for accurate and effective federated fine-tuning of foundation models. Our code is publicly available at https://github.com/RaghavSinghal10/fedex-lora.

The success of large pretrained models in natural language processing (NLP) and computer vision (CV) has opened new avenues for constructing foundation models for time series forecasting (TSF). Traditional TSF foundation models rely heavily on numerical data fitting. In contrast, the human brain is inherently skilled at processing visual information, prefer predicting future trends by observing visualized sequences. From a biomimetic perspective, utilizing models to directly process numerical sequences might not be the most effective route to achieving Artificial General Intelligence (AGI). This paper proposes ViTime, a novel Visual Intelligence-based foundation model for TSF. ViTime overcomes the limitations of numerical time series data fitting by utilizing visual data processing paradigms and employs a innovative data synthesis method during training, called Real Time Series (RealTS). Experiments on a diverse set of previously unseen forecasting datasets demonstrate that ViTime achieves state-of-the-art zero-shot performance, even surpassing the best individually trained supervised models in some situations. These findings suggest that visual intelligence can significantly enhance time series analysis and forecasting, paving the way for more advanced and versatile models in the field. The code for our framework is accessible at https://github.com/IkeYang/ViTime.

Large pretrained (e.g., "foundation") models exhibit distinct capabilities depending on the domain of data they are trained on. While these domains are generic, they may only barely overlap. For example, visual-language models (VLMs) are trained on Internet-scale image captions, but large language models (LMs) are further trained on Internet-scale text with no images (e.g., spreadsheets, SAT questions, code). As a result, these models store different forms of commonsense knowledge across different domains. In this work, we show that this diversity is symbiotic, and can be leveraged through Socratic Models (SMs): a modular framework in which multiple pretrained models may be composed zero-shot i.e., via multimodal-informed prompting, to exchange information with each other and capture new multimodal capabilities, without requiring finetuning. With minimal engineering, SMs are not only competitive with state-of-the-art zero-shot image captioning and video-to-text retrieval, but also enable new applications such as (i) answering free-form questions about egocentric video, (ii) engaging in multimodal assistive dialogue with people (e.g., for cooking recipes) by interfacing with external APIs and databases (e.g., web search), and (iii) robot perception and planning.

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology Foundation Models (PFMs), pretrained on large-scale histopathology data, have significantly enhanced both the extractor and aggregator, but they lack a systematic analysis framework. In this survey, we present a hierarchical taxonomy organizing PFMs through a top-down philosophy applicable to foundation model analysis in any domain: model scope, model pretraining, and model design. Additionally, we systematically categorize PFM evaluation tasks into slide-level, patch-level, multimodal, and biological tasks, providing comprehensive benchmarking criteria. Our analysis identifies critical challenges in both PFM development (pathology-specific methodology, end-to-end pretraining, data-model scalability) and utilization (effective adaptation, model maintenance), paving the way for future directions in this promising field. Resources referenced in this survey are available at https://github.com/BearCleverProud/AwesomeWSI.

Is bigger always better for time series foundation models? With the question in mind, we explore an alternative to training a single, large monolithic model: building a portfolio of smaller, pretrained forecasting models. By applying ensembling or model selection over these portfolios, we achieve competitive performance on large-scale benchmarks using much fewer parameters. We explore strategies for designing such portfolios and find that collections of specialist models consistently outperform portfolios of independently trained generalists. Remarkably, we demonstrate that post-training a base model is a compute-effective approach for creating sufficiently diverse specialists, and provide evidences that ensembling and model selection are more compute-efficient than test-time fine-tuning.

We present a joint forecasting framework for time series prediction that contrasts with traditional direct or recursive methods. This framework achieves state-of-the-art performance for our designed foundation model, YingLong, and reveals a novel scaling effect: longer outputs significantly enhance model accuracy due to delayed chain-of-thought reasoning in our non-causal approach. YingLong is a non-causal, bidirectional attention encoder-only transformer trained through masked token recovery, aligning more effectively with language understanding tasks than with generation tasks. Additionally, we boost performance by tackling output variance with a multi-input ensemble. We release four foundation models ranging from 6M to 300M parameters, demonstrating superior results in zero-shot tasks on the ETT and Weather datasets. YingLong achieves more than 60% best performance. To ensure generalizability, we assessed the models using the GIFT-Eval benchmark, which comprises 23 time series datasets across 7 domains. Yinglong significantly outperformed the best time-series foundation models, end-to-end trained models by 14% and 44% in rank respectively.The pretrained 300M model is available at https://huggingface.co/qcw1314/YingLong_300m

Chaotic systems are intrinsically sensitive to small errors, challenging efforts to construct predictive data-driven models of real-world dynamical systems such as fluid flows or neuronal activity. Prior efforts comprise either specialized models trained separately on individual time series, or foundation models trained on vast time series databases with little underlying dynamical structure. Motivated by dynamical systems theory, we present Panda, Patched Attention for Nonlinear DynAmics. We train Panda on a novel synthetic, extensible dataset of 2 times 10^4 chaotic dynamical systems that we discover using an evolutionary algorithm. Trained purely on simulated data, Panda exhibits emergent properties: zero-shot forecasting of unseen real world chaotic systems, and nonlinear resonance patterns in cross-channel attention heads. Despite having been trained only on low-dimensional ordinary differential equations, Panda spontaneously develops the ability to predict partial differential equations without retraining. We demonstrate a neural scaling law for differential equations, underscoring the potential of pretrained models for probing abstract mathematical domains like nonlinear dynamics.

Vision-language-action (VLA) models have emerged as the next generation of models in robotics. However, despite leveraging powerful pre-trained Vision-Language Models (VLMs), existing end-to-end VLA systems often lose key capabilities during fine-tuning as the model adapts to specific robotic tasks. We argue that a generalizable VLA model should retain and expand upon the VLM's core competencies: 1) Open-world embodied reasoning - the VLA should inherit the knowledge from VLM, i.e., recognize anything that the VLM can recognize, be capable of solving math problems, and possess visual-spatial intelligence, 2) Reasoning following - effectively translating the open-world reasoning into actionable steps for the robot. In this work, we introduce ChatVLA-2, a novel mixture-of-expert VLA model coupled with a specialized two-stage training pipeline designed to preserve the VLM's original strengths while enabling actionable reasoning. To validate our approach, we design a math-matching task wherein a robot interprets math problems written on a whiteboard and picks corresponding number cards from a table to solve equations. Remarkably, our method exhibits exceptional mathematical reasoning and OCR capabilities, despite these abilities not being explicitly trained within the VLA. Furthermore, we demonstrate that the VLA possesses strong spatial reasoning skills, enabling it to interpret novel directional instructions involving previously unseen objects. Overall, our method showcases reasoning and comprehension abilities that significantly surpass state-of-the-art imitation learning methods such as OpenVLA, DexVLA, and pi-zero. This work represents a substantial advancement toward developing truly generalizable robotic foundation models endowed with robust reasoning capacities.

Vision language model (VLM) has been designed for large scale image-text alignment as a pretrained foundation model. For downstream few shot classification tasks, parameter efficient fine-tuning (PEFT) VLM has gained much popularity in the computer vision community. PEFT methods like prompt tuning and linear adapter have been studied for fine-tuning VLM while low rank adaptation (LoRA) algorithm has rarely been considered for few shot fine-tuning VLM. The main obstacle to use LoRA for few shot fine-tuning is the catastrophic forgetting problem. Because the visual language alignment knowledge is important for the generality in few shot learning, whereas low rank adaptation interferes with the most informative direction of the pretrained weight matrix. We propose the complementary subspace low rank adaptation (Comp-LoRA) method to regularize the catastrophic forgetting problem in few shot VLM finetuning. In detail, we optimize the low rank matrix in the complementary subspace, thus preserving the general vision language alignment ability of VLM when learning the novel few shot information. We conduct comparison experiments of the proposed Comp-LoRA method and other PEFT methods on fine-tuning VLM for few shot classification. And we also present the suppression on the catastrophic forgetting problem of our proposed method against directly applying LoRA to VLM. The results show that the proposed method surpasses the baseline method by about +1.0\% Top-1 accuracy and preserves the VLM zero-shot performance over the baseline method by about +1.3\% Top-1 accuracy.

Pre-trained large language models demonstrate potential in extracting information from DNA sequences, yet adapting to a variety of tasks and data modalities remains a challenge. To address this, we propose DNAGPT, a generalized DNA pre-training model trained on over 200 billion base pairs from all mammals. By enhancing the classic GPT model with a binary classification task (DNA sequence order), a numerical regression task (guanine-cytosine content prediction), and a comprehensive token language, DNAGPT can handle versatile DNA analysis tasks while processing both sequence and numerical data. Our evaluation of genomic signal and region recognition, mRNA abundance regression, and artificial genomes generation tasks demonstrates DNAGPT's superior performance compared to existing models designed for specific downstream tasks, benefiting from pre-training using the newly designed model structure.

Time series classification is a fundamental task in healthcare and industry, yet the development of time series foundation models (TSFMs) remains limited by the scarcity of publicly available time series datasets. In this work, we propose Time Vision Transformer (TiViT), a framework that converts time series into images to leverage the representational power of frozen Vision Transformers (ViTs) pretrained on large-scale image datasets. First, we theoretically motivate our approach by analyzing the 2D patching of ViTs for time series, showing that it can increase the number of label-relevant tokens and reduce the sample complexity. Second, we empirically demonstrate that TiViT achieves state-of-the-art performance on standard time series classification benchmarks by utilizing the hidden representations of large OpenCLIP models. We explore the structure of TiViT representations and find that intermediate layers with high intrinsic dimension are the most effective for time series classification. Finally, we assess the alignment between TiViT and TSFM representation spaces and identify a strong complementarity, with further performance gains achieved by combining their features. Our findings reveal a new direction for reusing vision representations in a non-visual domain. Code is available at https://github.com/ExplainableML/TiViT.

This paper provides a simplification on OpenVision's architecture and loss design for enhancing its training efficiency. Following the prior vision-language pretraining works CapPa and AIMv2, as well as modern multimodal designs like LLaVA, our changes are straightforward: we remove the text encoder (and therefore the contrastive loss), retaining only the captioning loss as a purely generative training signal. We name this new version OpenVision 2. The initial results are promising: despite this simplification, OpenVision 2 competitively matches the original model's performance on a broad set of multimodal benchmarks while substantially cutting both training time and memory consumption. For example, with ViT-L/14, it reduces training time by about 1.5x (from 83h to 57h), and memory usage by about 1.8x (from 24.5GB to 13.8GB, equivalently allowing the maximum batch size to grow from 2k to 8k). This superior training efficiency also allows us to scale far beyond the largest vision encoder used in OpenVision, reaching more than 1 billion parameters. We hold a strong belief that this lightweight, generative-only paradigm is compelling for future vision encoder development in multimodal foundation models.

Time series foundation models (TSFMs) pretrained on data from multiple domains have shown strong performance on diverse modeling tasks. Various efforts have been made to develop foundation models specific to electroencephalography (EEG) data, which records brain electrical activity as time series. However, no comparative analysis of EEG-specific foundation models (EEGFMs) versus general TSFMs has been performed on EEG-specific tasks. We introduce a novel Spatial-Temporal Adapter with Multi-Head Pooling (STAMP), which leverages univariate embeddings produced by a general TSFM, implicitly models spatial-temporal characteristics of EEG data, and achieves performance comparable to state-of-the-art EEGFMs. A comprehensive analysis is performed on 8 benchmark datasets of clinical tasks using EEG for classification, along with ablation studies. Our proposed adapter is lightweight in trainable parameters and flexible in the inputs it can accommodate, supporting easy modeling of EEG data using TSFMs.

This paper revisits the standard pretrain-then-finetune paradigm used in computer vision for visual recognition tasks. Typically, state-of-the-art foundation models are pretrained using large scale (weakly) supervised datasets with billions of images. We introduce an additional pre-pretraining stage that is simple and uses the self-supervised MAE technique to initialize the model. While MAE has only been shown to scale with the size of models, we find that it scales with the size of the training dataset as well. Thus, our MAE-based pre-pretraining scales with both model and data size making it applicable for training foundation models. Pre-pretraining consistently improves both the model convergence and the downstream transfer performance across a range of model scales (millions to billions of parameters), and dataset sizes (millions to billions of images). We measure the effectiveness of pre-pretraining on 10 different visual recognition tasks spanning image classification, video recognition, object detection, low-shot classification and zero-shot recognition. Our largest model achieves new state-of-the-art results on iNaturalist-18 (91.3%), 1-shot ImageNet-1k (62.1%), and zero-shot transfer on Food-101 (96.0%). Our study reveals that model initialization plays a significant role, even for web-scale pretraining with billions of images.

Mimicking human behavior to actively learning from general experience and achieve artificial general intelligence has always been a human dream. Recent reinforcement learning (RL) based large-thinking models demonstrate impressive expert-level abilities, i.e., software and math, but still rely heavily on verifiable rewards in specific domains, placing a significant bottleneck to extend the performance boundary of general reasoning capabilities. In this work, we propose PretrainZero, a reinforcement active learning framework built on the pretraining corpus to extend RL from domain-specific post-training to general pretraining. PretrainZero features the following characteristics: 1) Active pretraining: inspired by the active learning ability of humans, PretrainZero learns a unified reasoning policy to actively identify reasonable and informative contents from pretraining corpus, and reason to predict these contents by RL. 2) Self-supervised learning: without any verifiable labels, pretrained reward models, or supervised fine-tuning, we directly pretrain reasoners from 3 to 30B base models on the general Wikipedia corpus using RL, significantly breaking the verification data-wall for general reasoning. 3) Verification scaling: by tackling increasingly challenging masked spans, PretrainZero substantially enhances the general reasoning abilities of pretrained base models. In reinforcement pretraining, PretrainZero improves Qwen3-4B-Base for 8.43, 5.96 and 10.60 on MMLU-Pro, SuperGPQA and math average benchmarks. In post-training, the pretrained models can also serve as reasoning foundation models for downstream RLVR tasks.

Understanding the semantics of individual regions or patches within unconstrained images, such as in open-world object detection, represents a critical yet challenging task in computer vision. Building on the success of powerful image-level vision-language (ViL) foundation models like CLIP, recent efforts have sought to harness their capabilities by either training a contrastive model from scratch with an extensive collection of region-label pairs or aligning the outputs of a detection model with image-level representations of region proposals. Despite notable progress, these approaches are plagued by computationally intensive training requirements, susceptibility to data noise, and deficiency in contextual information. To address these limitations, we explore the synergistic potential of off-the-shelf foundation models, leveraging their respective strengths in localization and semantics. We introduce a novel, generic, and efficient region recognition architecture, named RegionSpot, designed to integrate position-aware localization knowledge from a localization foundation model (e.g., SAM) with semantic information extracted from a ViL model (e.g., CLIP). To fully exploit pretrained knowledge while minimizing training overhead, we keep both foundation models frozen, focusing optimization efforts solely on a lightweight attention-based knowledge integration module. Through extensive experiments in the context of open-world object recognition, our RegionSpot demonstrates significant performance improvements over prior alternatives, while also providing substantial computational savings. For instance, training our model with 3 million data in a single day using 8 V100 GPUs. Our model outperforms GLIP by 6.5 % in mean average precision (mAP), with an even larger margin by 14.8 % for more challenging and rare categories.

Camouflaged object detection (COD) aims to segment camouflaged objects which exhibit very similar patterns with the surrounding environment. Recent research works have shown that enhancing the feature representation via the frequency information can greatly alleviate the ambiguity problem between the foreground objects and the background.With the emergence of vision foundation models, like InternImage, Segment Anything Model etc, adapting the pretrained model on COD tasks with a lightweight adapter module shows a novel and promising research direction. Existing adapter modules mainly care about the feature adaptation in the spatial domain. In this paper, we propose a novel frequency-guided spatial adaptation method for COD task. Specifically, we transform the input features of the adapter into frequency domain. By grouping and interacting with frequency components located within non overlapping circles in the spectrogram, different frequency components are dynamically enhanced or weakened, making the intensity of image details and contour features adaptively adjusted. At the same time, the features that are conducive to distinguishing object and background are highlighted, indirectly implying the position and shape of camouflaged object. We conduct extensive experiments on four widely adopted benchmark datasets and the proposed method outperforms 26 state-of-the-art methods with large margins. Code will be released.

Deep neural networks have achieved success across a wide range of applications, including as models of human behavior in vision tasks. However, neural network training and human learning differ in fundamental ways, and neural networks often fail to generalize as robustly as humans do, raising questions regarding the similarity of their underlying representations. What is missing for modern learning systems to exhibit more human-like behavior? We highlight a key misalignment between vision models and humans: whereas human conceptual knowledge is hierarchically organized from fine- to coarse-scale distinctions, model representations do not accurately capture all these levels of abstraction. To address this misalignment, we first train a teacher model to imitate human judgments, then transfer human-like structure from its representations into pretrained state-of-the-art vision foundation models. These human-aligned models more accurately approximate human behavior and uncertainty across a wide range of similarity tasks, including a new dataset of human judgments spanning multiple levels of semantic abstractions. They also perform better on a diverse set of machine learning tasks, increasing generalization and out-of-distribution robustness. Thus, infusing neural networks with additional human knowledge yields a best-of-both-worlds representation that is both more consistent with human cognition and more practically useful, thus paving the way toward more robust, interpretable, and human-like artificial intelligence systems.

Recent unified multi-modal encoders align a wide range of modalities into a shared representation space, enabling diverse cross-modal tasks. Despite their impressive capabilities, the robustness of these models under adversarial perturbations remains underexplored, which is a critical concern for safety-sensitive applications. In this work, we present the first comprehensive study of adversarial vulnerability in unified multi-modal encoders. We find that even mild adversarial perturbations lead to substantial performance drops across all modalities. Non-visual inputs, such as audio and point clouds, are especially fragile, while visual inputs like images and videos also degrade significantly. To address this, we propose an efficient adversarial calibration framework that improves robustness across modalities without modifying pretrained encoders or semantic centers, ensuring compatibility with existing foundation models. Our method introduces modality-specific projection heads trained solely on adversarial examples, while keeping the backbone and embeddings frozen. We explore three training objectives: fixed-center cross-entropy, clean-to-adversarial L2 alignment, and clean-adversarial InfoNCE, and we introduce a regularization strategy to ensure modality-consistent alignment under attack. Experiments on six modalities and three Bind-style models show that our method improves adversarial robustness by up to 47.3 percent at epsilon = 4/255, while preserving or even improving clean zero-shot and retrieval performance with less than 1 percent trainable parameters.

Markov jump processes are continuous-time stochastic processes which describe dynamical systems evolving in discrete state spaces. These processes find wide application in the natural sciences and machine learning, but their inference is known to be far from trivial. In this work we introduce a methodology for zero-shot inference of Markov jump processes (MJPs), on bounded state spaces, from noisy and sparse observations, which consists of two components. First, a broad probability distribution over families of MJPs, as well as over possible observation times and noise mechanisms, with which we simulate a synthetic dataset of hidden MJPs and their noisy observation process. Second, a neural network model that processes subsets of the simulated observations, and that is trained to output the initial condition and rate matrix of the target MJP in a supervised way. We empirically demonstrate that one and the same (pretrained) model can infer, in a zero-shot fashion, hidden MJPs evolving in state spaces of different dimensionalities. Specifically, we infer MJPs which describe (i) discrete flashing ratchet systems, which are a type of Brownian motors, and the conformational dynamics in (ii) molecular simulations, (iii) experimental ion channel data and (iv) simple protein folding models. What is more, we show that our model performs on par with state-of-the-art models which are finetuned to the target datasets.

We present Gyan AI Paramanu ("atom"), a family of novel language models for Indian languages. It is a collection of auto-regressive monolingual, bilingual, and multilingual Indic language models pretrained from scratch on a single GPU for 10 Indian languages (Assamese, Bangla, Hindi, Konkani, Maithili, Marathi, Odia, Sanskrit, Tamil, Telugu) across 5 scripts (Bangla, Devanagari, Odia, Tamil, Telugu) of varying sizes ranging from 13.29M to 367.5M.The models are pretrained with a context size of 1024 on a single GPU. The models are very efficient, small, fast, and powerful. We have also developed an efficient most advanced Indic tokenizer that can even tokenize unseen languages. In order to avoid the "curse of multi-linguality" in our multilingual mParamanu model, we pretrained on comparable corpora by typological grouping using the same script. We performed human evaluation of our pretrained models for open end text generation on grammar, coherence, creativity, and factuality metrics for Bangla, Hindi, and Sanskrit. Our Bangla, Hindi, and Sanskrit models outperformed GPT-3.5-Turbo (ChatGPT), Bloom 7B, LLaMa-2 7B, OPT 6.7B, GPT-J 6B, GPTNeo 1.3B, GPT2-XL large language models (LLMs) by a large margin despite being smaller in size by 66 to 20 times compared to standard 7B LLMs. To run inference on our pretrained models, CPU is enough, and GPU is not needed. We also instruction-tuned our pretrained Bangla, Hindi, Marathi, Tamil, and Telugu models on 23k instructions in respective languages. Our pretrained and instruction-tuned models which are first of its kind, most powerful efficient small generative language models ever developed for Indic languages, and the various results lead to the conclusion that high quality generative language models are possible without high amount of compute power and humongous number of parameters. We plan to release our models at https://www.bharatgpts.com.

Machine learning has demonstrated remarkable performance over finite datasets, yet whether the scores over the fixed benchmarks can sufficiently indicate the model's performance in the real world is still in discussion. In reality, an ideal robust model will probably behave similarly to the oracle (e.g., the human users), thus a good evaluation protocol is probably to evaluate the models' behaviors in comparison to the oracle. In this paper, we introduce a new robustness measurement that directly measures the image classification model's performance compared with a surrogate oracle (i.e., a foundation model). Besides, we design a simple method that can accomplish the evaluation beyond the scope of the benchmarks. Our method extends the image datasets with new samples that are sufficiently perturbed to be distinct from the ones in the original sets, but are still bounded within the same image-label structure the original test image represents, constrained by a foundation model pretrained with a large amount of samples. As a result, our new method will offer us a new way to evaluate the models' robustness performance, free of limitations of fixed benchmarks or constrained perturbations, although scoped by the power of the oracle. In addition to the evaluation results, we also leverage our generated data to understand the behaviors of the model and our new evaluation strategies.

Cardiac biosignals, such as electrocardiograms (ECG) and photoplethysmograms (PPG), are of paramount importance for the diagnosis, prevention, and management of cardiovascular diseases, and have been extensively used in a variety of clinical tasks. Conventional deep learning approaches for analyzing these signals typically rely on homogeneous datasets and static bespoke models, limiting their robustness and generalizability across diverse clinical settings and acquisition protocols. In this study, we present a cardiac sensing foundation model (CSFM) that leverages advanced transformer architectures and a generative, masked pretraining strategy to learn unified representations from vast, heterogeneous health records. Our model is pretrained on an innovative multi-modal integration of data from multiple large-scale datasets (including MIMIC-III-WDB, MIMIC-IV-ECG, and CODE), comprising cardiac signals and the corresponding clinical or machine-generated text reports from approximately 1.7 million individuals. We demonstrate that the embeddings derived from our CSFM not only serve as effective feature extractors across diverse cardiac sensing scenarios, but also enable seamless transfer learning across varying input configurations and sensor modalities. Extensive evaluations across diagnostic tasks, demographic information recognition, vital sign measurement, clinical outcome prediction, and ECG question answering reveal that CSFM consistently outperforms traditional one-modal-one-task approaches. Notably, CSFM exhibits robust performance across multiple ECG lead configurations from standard 12-lead systems to single-lead setups, and in scenarios where only ECG, only PPG, or a combination thereof is available. These findings highlight the potential of CSFM as a versatile and scalable solution, for comprehensive cardiac monitoring.

Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer diagnosis from dermoscopic images, they struggle to meet the complex, multimodal requirements of clinical practice. Here, we introduce PanDerm, a multimodal dermatology foundation model pretrained through self-supervised learning on over 2 million real-world skin disease images from 11 clinical institutions across 4 imaging modalities. We evaluated PanDerm on 28 diverse benchmarks, including skin cancer screening, risk stratification, differential diagnosis of common and rare skin conditions, lesion segmentation, longitudinal monitoring, and metastasis prediction and prognosis. PanDerm achieved state-of-the-art performance across all evaluated tasks, often outperforming existing models when using only 10% of labeled data. We conducted three reader studies to assess PanDerm's potential clinical utility. PanDerm outperformed clinicians by 10.2% in early-stage melanoma detection through longitudinal analysis, improved clinicians' skin cancer diagnostic accuracy by 11% on dermoscopy images, and enhanced non-dermatologist healthcare providers' differential diagnosis by 16.5% across 128 skin conditions on clinical photographs. These results demonstrate PanDerm's potential to improve patient care across diverse clinical scenarios and serve as a model for developing multimodal foundation models in other medical specialties, potentially accelerating the integration of AI support in healthcare. The code can be found at https://github.com/SiyuanYan1/PanDerm.

Conventional task-specific electrocardiogram (ECG) analysis models require large annotated datasets to train. Foundation models mitigate this burden by leveraging self-supervised pretraining; however, the scarcity of open-weight ECG foundation models hinders adoption and cross-study comparability. We present ECG-FM, an open foundation model for ECG analysis, and conduct a study using a dataset of 1.5 million ECGs. ECG-FM is a transformer-based model pretrained using a hybrid contrastive and generative self-supervised learning approach. Our downstream tasks include predicting reduced left ventricular ejection fraction (LVEF) and ECG interpretation labels, where we release a benchmark task on the MIMIC-IV-ECG dataset. We affirm that ECG-FM is robust, label-efficient, and functionally discriminative by showcasing data scaling experiments, performing a latent space analysis, and generating saliency maps. ECG-FM markedly outperforms task-specific models in the small-to-medium-scale data regime and demonstrates cross-dataset generalizability, achieving high AUROC on many clinically salient labels such as atrial fibrillation (0.996) and LVEF<=40% (0.929). We release our code, model weights, and benchmark task at https://github.com/bowang-lab/ECG-FM/.

The growing success of Vision-Language-Action (VLA) models stems from the promise that pretrained Vision-Language Models (VLMs) can endow agents with transferable world knowledge and vision-language (VL) grounding, laying a foundation for action models with broader generalization. Yet when these VLMs are adapted to the action modality, it remains unclear to what extent their original VL representations and knowledge are preserved. In this work, we conduct a systematic study of representation retention during VLA fine-tuning, showing that naive action fine-tuning leads to degradation of visual representations. To characterize and measure these effects, we probe VLA's hidden representations and analyze attention maps, further, we design a set of targeted tasks and methods that contrast VLA models with their counterpart VLMs, isolating changes in VL capabilities induced by action fine-tuning. We further evaluate a range of strategies for aligning visual representations and introduce a simple yet effective method that mitigates degradation and yields improved generalization to out-of-distribution (OOD) scenarios. Taken together, our analysis clarifies the trade-off between action fine-tuning and the degradation of VL representations and highlights practical approaches to recover inherited VL capabilities. Code is publicly available: https://blind-vla-paper.github.io

Genomic (DNA) sequences encode an enormous amount of information for gene regulation and protein synthesis. Similar to natural language models, researchers have proposed foundation models in genomics to learn generalizable features from unlabeled genome data that can then be fine-tuned for downstream tasks such as identifying regulatory elements. Due to the quadratic scaling of attention, previous Transformer-based genomic models have used 512 to 4k tokens as context (<0.001% of the human genome), significantly limiting the modeling of long-range interactions in DNA. In addition, these methods rely on tokenizers to aggregate meaningful DNA units, losing single nucleotide resolution where subtle genetic variations can completely alter protein function via single nucleotide polymorphisms (SNPs). Recently, Hyena, a large language model based on implicit convolutions was shown to match attention in quality while allowing longer context lengths and lower time complexity. Leveraging Hyenas new long-range capabilities, we present HyenaDNA, a genomic foundation model pretrained on the human reference genome with context lengths of up to 1 million tokens at the single nucleotide-level, an up to 500x increase over previous dense attention-based models. HyenaDNA scales sub-quadratically in sequence length (training up to 160x faster than Transformer), uses single nucleotide tokens, and has full global context at each layer. We explore what longer context enables - including the first use of in-context learning in genomics for simple adaptation to novel tasks without updating pretrained model weights. On fine-tuned benchmarks from the Nucleotide Transformer, HyenaDNA reaches state-of-the-art (SotA) on 12 of 17 datasets using a model with orders of magnitude less parameters and pretraining data. On the GenomicBenchmarks, HyenaDNA surpasses SotA on all 8 datasets on average by +9 accuracy points.

In this work, we propose aligning pretrained visual encoders to serve as tokenizers for latent diffusion models in image generation. Unlike training a variational autoencoder (VAE) from scratch, which primarily emphasizes low-level details, our approach leverages the rich semantic structure of foundation encoders. We introduce a three-stage alignment strategy: (1) freeze the encoder and train an adapter and a decoder to establish a semantic latent space; (2) jointly optimize all components with an additional semantic preservation loss, enabling the encoder to capture perceptual details while retaining high-level semantics; and (3) refine the decoder for improved reconstruction quality. This alignment yields semantically rich image tokenizers that benefit diffusion models. On ImageNet 256times256, our tokenizer accelerates the convergence of diffusion models, reaching a gFID of 1.90 within just 64 epochs, and improves generation both with and without classifier-free guidance. Scaling to LAION, a 2B-parameter text-to-image model trained with our tokenizer consistently outperforms FLUX VAE under the same training steps. Overall, our method is simple, scalable, and establishes a semantically grounded paradigm for continuous tokenizer design.

We present Sapiens, a family of models for four fundamental human-centric vision tasks - 2D pose estimation, body-part segmentation, depth estimation, and surface normal prediction. Our models natively support 1K high-resolution inference and are extremely easy to adapt for individual tasks by simply fine-tuning models pretrained on over 300 million in-the-wild human images. We observe that, given the same computational budget, self-supervised pretraining on a curated dataset of human images significantly boosts the performance for a diverse set of human-centric tasks. The resulting models exhibit remarkable generalization to in-the-wild data, even when labeled data is scarce or entirely synthetic. Our simple model design also brings scalability - model performance across tasks improves as we scale the number of parameters from 0.3 to 2 billion. Sapiens consistently surpasses existing baselines across various human-centric benchmarks. We achieve significant improvements over the prior state-of-the-art on Humans-5K (pose) by 7.6 mAP, Humans-2K (part-seg) by 17.1 mIoU, Hi4D (depth) by 22.4% relative RMSE, and THuman2 (normal) by 53.5% relative angular error.

We introduce CogVLM, a powerful open-source visual language foundation model. Different from the popular shallow alignment method which maps image features into the input space of language model, CogVLM bridges the gap between the frozen pretrained language model and image encoder by a trainable visual expert module in the attention and FFN layers. As a result, CogVLM enables deep fusion of vision language features without sacrificing any performance on NLP tasks. CogVLM-17B achieves state-of-the-art performance on 10 classic cross-modal benchmarks, including NoCaps, Flicker30k captioning, RefCOCO, RefCOCO+, RefCOCOg, Visual7W, GQA, ScienceQA, VizWiz VQA and TDIUC, and ranks the 2nd on VQAv2, OKVQA, TextVQA, COCO captioning, etc., surpassing or matching PaLI-X 55B. Codes and checkpoints are available at https://github.com/THUDM/CogVLM.

We introduce Jais and Jais-chat, new state-of-the-art Arabic-centric foundation and instruction-tuned open generative large language models (LLMs). The models are based on the GPT-3 decoder-only architecture and are pretrained on a mixture of Arabic and English texts, including source code in various programming languages. With 13 billion parameters, they demonstrate better knowledge and reasoning capabilities in Arabic than any existing open Arabic and multilingual models by a sizable margin, based on extensive evaluation. Moreover, the models are competitive in English compared to English-centric open models of similar size, despite being trained on much less English data. We provide a detailed description of the training, the tuning, the safety alignment, and the evaluation of the models. We release two open versions of the model -- the foundation Jais model, and an instruction-tuned Jais-chat variant -- with the aim of promoting research on Arabic LLMs. Available at https://huggingface.co/inception-mbzuai/jais-13b-chat