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Prokaryotic Genome CDS Annotation Summary

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In this repository, we present the evaluation datasets for prokaryotic genome annotation tasked. Through comprehensive evaluations, GENERanno-cds-annotator achieves superior accuracy compared to traditional HMM-based methods (e.g., GLIMMER3, GeneMarkS2, Prodigal) and recent LLM-based approaches (e.g., GeneLM), while demonstrating exceptional generalization ability on archaeal genomes.

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