question stringlengths 30 149 | options stringlengths 60 338 | explanation stringlengths 114 541 | question_type stringclasses 11
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What pregnancy category does Thiacetazone + Isoniazid belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Thiacetazone + Isoniazid belongs to pregnancy category C. This means that either studies in animals have revealed adverse effects on the fetus and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only if the potential benefit justifies t... | pregnancy_category_mcq | medium | pregnancy_category | C |
When should Bromocriptine NOT be used? | {"A": "In patients with ischaemic heart disease", "B": "In women with toxaemia of pregnancy", "C": "In postpartum women with hypertension", "D": "In patients with hypersensitivity to ergot alkaloids", "E": "All of the above"} | Bromocriptine is contraindicated in all the mentioned conditions. It should not be used in patients with ischaemic heart disease, women with toxaemia of pregnancy, postpartum women with hypertension, and in patients with hypersensitivity to bromocriptine or other ergot alkaloids. These contraindications are due to the ... | contraindications_mcq | medium | contraindications | E |
What is the recommended oral dose of Omeprazole for treating benign gastric ulcers? | {"A": "10 mg once daily for 4 weeks", "B": "20 mg once daily for 8 weeks", "C": "40 mg once daily for 4 weeks", "D": "60 mg once daily for 8 weeks", "E": "None of the above"} | The recommended oral dose of Omeprazole for treating benign gastric ulcers is 20 mg once daily for 8 weeks. This dosage is specifically indicated in the National Formulary of India for gastric ulcers. In severe cases, the dose may be increased to 40 mg, but 20 mg is the standard initial dose. | dose_mcq | medium | dose | B |
What pregnancy category does Ibuprofen belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Ibuprofen belongs to pregnancy category C. This means that either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Ibuprofen should be given only if the potential benefit j... | pregnancy_category_mcq | medium | pregnancy_category | C |
In which condition should Zolpidem be avoided? | {"A": "Severe hepatic insufficiency", "B": "Mild insomnia", "C": "Anxiety disorders", "D": "Chronic pain", "E": "None of the above"} | Zolpidem should be avoided in patients with severe hepatic insufficiency. This is because the liver plays a crucial role in metabolizing Zolpidem, and severe liver impairment can lead to excessive accumulation of the drug, potentially causing serious side effects or toxicity. | contraindications_mcq | medium | contraindications | A |
What is the maximum dose of Dopamine that can be given to an adult patient with cardiogenic shock? | {"A": "10 \u00b5g/kg/min", "B": "20 \u00b5g/kg/min", "C": "30 \u00b5g/kg/min", "D": "50 \u00b5g/kg/min", "E": "100 \u00b5g/kg/min"} | For adult patients with cardiogenic shock, Dopamine can be administered intravenously with a maximum dose of 50 µg/kg/min in seriously ill patients. The dose is typically started at 2 to 5 µg/kg/min and gradually increased according to blood pressure, cardiac output, and urine output. | dose_mcq | medium | dose | D |
What pregnancy category does Benzathine Benzyl Penicillin belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Benzathine Benzyl Penicillin belongs to pregnancy Category B. This means that either animal studies have not demonstrated a risk to the fetus and there are no adequate studies in pregnant women, or animal studies have shown an adverse effect that was not confirmed in controlled studies in women in the first trimester. | pregnancy_category_mcq | medium | pregnancy_category | B |
When should Cetrimide NOT be used? | {"A": "In patients with hypersensitivity to Cetrimide", "B": "In patients with open wounds", "C": "In patients with respiratory infections", "D": "In patients with skin rashes", "E": "None of the above"} | Cetrimide is contraindicated in patients with hypersensitivity to the drug. Hypersensitivity reactions can lead to severe allergic responses, potentially causing anaphylaxis. It is crucial to avoid using Cetrimide in patients with known hypersensitivity to ensure patient safety. | contraindications_mcq | medium | contraindications | A |
What is the recommended dose of 50% glucose solution for treating hypoglycemia in adults? | {"A": "10 ml", "B": "25 ml", "C": "50 ml", "D": "100 ml", "E": "None of the above"} | For the treatment of hypoglycemia in adults, the recommended dose of 50% glucose solution is 25 ml, infused into a large vein. This provides a rapid increase in blood glucose levels to counteract hypoglycemia. | dose_mcq | medium | dose | B |
What pregnancy category does Dapsone belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Dapsone belongs to Pregnancy Category C. This means that either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only if the potentia... | pregnancy_category_mcq | medium | pregnancy_category | C |
When should Benzyl Penicillin NOT be used? | {"A": "In patients with hypersensitivity to penicillins", "B": "In patients with neurosyphilis", "C": "In patients with streptococcal infections", "D": "In patients with pneumococcal meningitis", "E": "None of the above"} | Benzyl Penicillin is contraindicated in patients with hypersensitivity to penicillins. This is due to the risk of severe allergic reactions, including anaphylaxis. Neurosyphilis, streptococcal infections, and pneumococcal meningitis are actually indications for Benzyl Penicillin use, not contraindications. | contraindications_mcq | medium | contraindications | A |
What is the weekly intravenous dose of Vincristine for adults? | {"A": "0.7 mg/m\u00b2 body surface area", "B": "1.4 mg/m\u00b2 body surface area", "C": "2.1 mg/m\u00b2 body surface area", "D": "2.8 mg/m\u00b2 body surface area", "E": "None of the above"} | The weekly intravenous dose of Vincristine for adults is 1.4 mg/m² body surface area. This is the standard dosage recommended in the National Formulary of India for adult patients receiving Vincristine therapy. | dose_mcq | medium | dose | B |
What pregnancy category does Lamivudine + Zidovudine belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Lamivudine + Zidovudine belongs to Pregnancy Category C. This means that either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only... | pregnancy_category_mcq | medium | pregnancy_category | C |
When should Methyldopa NOT be used? | {"A": "In patients with active liver disease", "B": "In patients with depression", "C": "In patients using MAO inhibitors", "D": "In patients with pheochromocytoma", "E": "All of the above"} | Methyldopa is contraindicated in all of these conditions. It should not be used in patients with active liver disease due to the risk of hepatotoxicity. Depression can be worsened by Methyldopa. Concurrent use with MAO inhibitors can lead to hypertensive crisis. Methyldopa can mask the signs of pheochromocytoma and int... | contraindications_mcq | medium | contraindications | E |
What pregnancy category does Omeprazole belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Omeprazole belongs to Pregnancy Category C. This means that either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only if the poten... | pregnancy_category_mcq | medium | pregnancy_category | C |
When should Quinidine NOT be used? | {"A": "In patients with complete heart block", "B": "In patients with myasthenia gravis", "C": "In patients with a history of embolism", "D": "In patients with hypertension", "E": "A, B, and C"} | Quinidine is contraindicated in patients with complete heart block, myasthenia gravis, and a history of embolism. These conditions can be exacerbated by Quinidine, potentially leading to serious complications. Hypertension is not a specific contraindication for Quinidine. | contraindications_mcq | medium | contraindications | E |
What pregnancy category does Calcium Carbonate + Vitamin D3 belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Calcium Carbonate + Vitamin D3 belongs to Pregnancy Category A. This means controlled studies in women have failed to demonstrate a risk to the fetus in the first trimester (and there is no evidence of a risk in later trimesters), and the possibility of fetal harm appears remote. | pregnancy_category_mcq | medium | pregnancy_category | A |
What pregnancy category does Bleomycin belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Bleomycin belongs to pregnancy category D. This means there is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffecti... | pregnancy_category_mcq | medium | pregnancy_category | D |
What pregnancy category does Lorazepam belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Lorazepam belongs to pregnancy category D. This means there is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk in certain situations (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be... | pregnancy_category_mcq | medium | pregnancy_category | D |
What pregnancy category does Ketoconazole belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Ketoconazole belongs to pregnancy category C. This means that either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only if the pot... | pregnancy_category_mcq | medium | pregnancy_category | C |
What pregnancy category does Testosterone belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Testosterone belongs to pregnancy Category X. This means that studies in animals or humans have demonstrated fetal abnormalities, or there is evidence of fetal risk based on human experience. The risk of using Testosterone in pregnant women clearly outweighs any possible benefit. Testosterone is contraindicated in wome... | pregnancy_safety_mcq | medium | pregnancy_category | E |
What pregnancy category does Flunarizine belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Flunarizine belongs to Pregnancy Category C. This means that either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only if the pote... | pregnancy_category_mcq | medium | pregnancy_category | C |
What pregnancy category does Melphalan belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Melphalan belongs to pregnancy category D. This means there is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffecti... | pregnancy_category_mcq | medium | pregnancy_category | D |
What pregnancy category does Esmolol belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Esmolol belongs to Pregnancy Category C. This means that either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only if the potentia... | pregnancy_safety_mcq | medium | pregnancy_category | C |
What pregnancy category does Proguanil belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Proguanil belongs to pregnancy category B. This means that either animal studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women, or animal studies have shown an adverse effect that was not confirmed in controlled studies in women in the first trimester (and there is no evidence... | pregnancy_category_mcq | medium | pregnancy_category | B |
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